Curriculum Vitae

Name : Professor Sayed Mohamed Ahmed Date of birth : Nov. 25, 1954. Place of birth : Minya, Egypt Nationality : Egyptian. Marital Status : Married, 5 children Mailing address: Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt. Phone # Home: (088) 2146046 /(088) 2146044 Work: (088) 2411855 (Secretary) / (088) 2411306 Mobile # 01009682004 Fax # (088) 2312564 / (088) 2332776 E-Mail: smaa54@yahoo.com

Positions, fellowships, research grants (national and international) - 9/2011 ll now: Head of the department of industrial pharmacy. - 3/2008-9/2011 : Professor in Department of Industrial Pharmacy, Assiut University. - 10/2007-3/2008: Vice Dean of the student affairs, Faculty of Pharmacy, Assiut Univ. - 1/2005-10/2007: Head of the department of Industrial Pharmacy, Assiut University.. - 9/1998 – 3/1999 : Professor in Department of Industrial Pharmacy, Assiut Univ. - 1/1998 - 9/1998 : Head of the Department of Industrial Pharmacy, Assiut Univ. - 7/1993 -1/1998 : Associate professor, Dept. of Industrial Pharmacy, Assiut Univ. -1/ 1992 -1/ 1994 : Research Inves gator 1, The Popula on Council, Center of Biomedical Research, New York, N.Y., USA. -7/ 1987 -7/ 1993 : Lecturer, Faculty of Pharmacy, Assiut University. - 8/1989 -1/1990: Postdoctoral peace Fellow, Dept. Pharmaceutics, College of Pharmacy, University of Florida, JHMHC, Gainesville, USA -2/ 1990 -1/1991: Third World Academy of sciences Postdoctoral fellow, Institute "G.Ronzoni" for Chemical and Biochemical research, Milan (Italy). -2/19 91 -6/ 1991: Research fellow for Crinos Pharm. Co., Viale Guardi, Milan (Italy). -10/1984-10/1986: Graduate research assistant, Pharmacy, Bradford Univ., England -7/ 1982 -7/ 1987: Assistant lecturer, Dept of Industrial Pharmacy, Assiut University. -10/1977-7/1982: Teaching assistant, Dept of Industrial Pharmacy, Assiut University.

Education - Professor: Pharmaceu cal Technology and Industrial Pharmacy, September/1998. - Associate professor: Pharm. Technology and Industrial Pharmacy, June /1993. - Ph. D: Industrial Pharmacy (Joint project/ Channel system…College of pharmacy, Bradford University – United kingdom), July 1987 - M. Sc.: Industrial Pharmacy, Assiut University, Egypt, July/1982. - Postgraduate Courses studied during Master degree, ( general grade "Excellent"). - B.Sc.: Pharmacy, May 1977, Assiut Univ. General grade "Very good/Degree honour"

Teaching Experience and fields of interest

- Teaching undergraduate and postgraduate students in Universities of Assiut, Alazhar, Miser International & Nahda university in Egypt.

- Industrial Pharmacy and Pharmaceutics (Pharm. calculations, Solutions, Biopharmaceutics, Dispersion systems, Solid dosage forms, Design and formulation of various dosage forms, Physical pharmacy, Pharmacy regulations, Hospital pharmacy, Stability, Advanced Industrial Pharmacy, Solution technology, Tablet technology, Solid state stability, Modern drug delivery systems, Research planning,Drug design, Modern Pharmaceutics, Quality control, GMP…….).

- Preformulation & formulation technology. - Thermal Techniques: DSC and DTA. - Chemical analysis: Various spectrophotometric and chromatographic methods

(I.R., U.V., Fluorometric analysis, preparative TLC and HPLC)., inclusion Complexation.

- Physicochemical incompatibility testing: Drug-drug, and drug-excipient interactions.

- Solubilization: Micellar, hydrotropy, neosomes, and cosolvency. - Dissolution technology. - Solid dispersions, Polymorphism, Phase

diagrams. - Ultrafiltration techniques. - Stability of drugs in solution and solid state. - Formulation and evaluation of subdermal Implants for controlled release of

drugs. - Interaction of lipids and peptides with cyclodextrins - Purification of lipids and peptides from natural contaminants. -

Thermodynamics. - Quality control. – cGMP - Sterile product production

technology

Prizes -National Research Prize in Pharm. & Medical Science, 1996 -The Na onal Medal of Excellence in Science 1998 -Excellence in Pharm. science, 2006 (Assiut university)

International research awards and Grants: Third World Academy of Science (TWAS) Award for Training in Italian

Laboratories, 1991-1992. Population Council Postdoctoral Research Award, New York, USA, 1992-1994. Crinos Pharmaco Biological Pharm. Company Research Grant, December 1990. Peace Fellowship Award, USA, Bradford University, August, 1989-January, 1991

Patents registered in the National Academy of sciences, Egy )3(مستند

Arab Republic of Egypt

Ministry of State for Scientific Research and Technology Academy of Scientific Research and Technology

Egyptian Patent Office

(22) (21) (44) (45) (11)

Int. Cl.6

1.

2. 3.

Prof. Ahmed Faak Ameen

Prof. Sayed Mohamed Ahmed Ahmed

Prof. Sayed Hassan Sayed Khidr

براءة أصلیة (12)

Combination of N-acetyl cysteine (NAC) and folic acid in the form of tablets for the treatment of unexplained relapsed pregnancy loss" The abstract in English Language (Not more than 100 words)

Title: "Combination of N-acetyl cysteine (NAC) and folic acid in the form of tablets for the treatment of unexplained relapsed pregnancy loss"

English abstract:

Patent

Conferences and workshops attendance:

1. 2nd Int, Sokhna, Egypt, . Conference in basic and applied sciences, April 2014. 2. First workshop on Pham. Manufacturing and GMP, Nahda University, Feb 2014 3. Future Interna onal conference on Pharm. Sci. Cairo, Egypt, February, 2013. 4. Future International workshop on tablet manufacturing, Cairo, Egypt, April,

2013. 5. International conference on basic&applied science, Hurghada, Egypt, 2012 6. Egyptian association of viral hepatitis conference, Assiut, Egypt, 2012. 7. International Conference of Pharm.Sci, Alzaytoonah & Tolido univ.,Jordan, 2012. 8. 8th Intrna onal conference of pharmaceu cal science..Assiut, March 2012. 9. 13th sci. Conference of gastroenterology&liver disease, March 2012.

10. 32nd conference of Pharm. Sci. of Egyp an Pharm. Society, Dec. 2011. 11. 13th conference of Arabic Na on Society, MUST, Cairo, Egypt, May, 2010 12. The first international conference in biotechnology, KSU, Saudia, Feb. 2009. 13. ASIDA conference on infec ous diseases, Cairo, Egypt, April 2007. 14. Jordanian Interna onal Conference of Pharm. Sci., Alzaytoonah Univ., 2006. 15. Al-Azhar Interna onal Conference for pharmaceu cal Sciences, Egypt, 2006. 16. 5th international Saudi pharmacy conference, Saudi Arabia, Riyadh, 1999. 17. 1 st Scien fic conference for Phar. Sci. Assiut Univ. Assiut, Egypt, March 1998. 18. 37th Scien fic mee ng of Syria, Damascus,1997. 19. First Interna onal Conference on Sci. & Advanced Technology, Egypt, 1996. 20. XXV International conference of pharmaceu cal sciences, Cairo, Egypt, 1996. 21. 1st International conference of Faculty of science, Assiut, Egypt, Nov. 1996. 22. Na onal Conference for the control of Schistosomiasis, Assiut, Egypt, 1995. 23. Egyptian-German Conference on Medicinal Plants, Assiut, Egypt, 1995. 24. AAPS Ninth Annual Mee ng and Exposi on, San Deigo, California, USA, 1994. 25. The Second International Conference on Pharmaceutical Science and 26. Technology of the Fine Par cle Society, East Brunswick, NJ, USA, 1994. 27. AAPS Eastern Regional Mee ng, New Brunswick, New Jersey, USA, 1994. 28. International Contraceptive Research Meetings, New York, USA, 1993-1994. 29. 23rd Egyp an Pharmaceu cal Conference, Cairo, Egypt, 1993. 30. 20th International Symposium on Controlled Release, Washington, USA, 1993. 31. Third Conference of Hospital Pharmacy, Assiut, Egypt, 1992. 32. First Egyptian-Italian Symposium on Biotechnology, Assiut, Egypt, 1992. 33. The First Na onal Symposium on Herbal Medicine, Assuit, Egypt. 1992. 34. Egyptian Pharmaceutical Conference of Pharm. Society, Cairo, Egypt, 1991. 35. Second Anglo-Egyptian Pharmaceutical Conference, Alexandria- Egypt, 1991. 36. VIth European Symposium (Carbohydrate Chem.) Scotland, England, Sep. 1991..

International published books

Training Courses Attended:

1) GMP and pharm. manufacturing: UK and USA. 2) Training course in chromatographic methods , Cairo Univ., Egypt, 1998. 3) An oxidants workshop, Assiut, Egypt, 1996. 4) 1st Workshop on Environmental Pollu on, Egypt, 1996. 5) Training Course in Electron Microscope, Assiut, Egypt 1996. 6) Training in animal Science lab., Rockefeller univ., New York, USA, 1993.

Society memberships: 1. Egyp an Pharmaceu cal associa on, 1991-now. 2. American Associa on for the Advancement of Science (AAAS), 1993, 1994. 3. Controlled Release Society (CRS) , 1993, 1994. 4. American Associa on of Pharmaceu cal Scien st, (AAPS), 1989 - 1995. 5. ASIDA infectious disease society, Cairo, Egypt. 6. Pharmacy Syndicate in Egypt.

Theses Supervision - Evaluation of novel biodegradable polymers, Ph.D., Hesham Mohamed. Joint project:Liverpool John University, UK, Graduated. - Preparation and evaluation of sustained release tablets containing either Nitrofurantoin or Phanazopyridine hydrochloride:Ph.D., Adel. Ali, Egypt, Graduated. - Interaction of Clonazepam with Macromolecules : M.sc., Gamal M. R., Egypt, Graduated. - Pharmaceutical studies on the interaction of some diuretics with macromolecules: M.sc., Amal Kamal Hussein, Egypt, Graduated. - New approaches for loratidine formulation: M.Sc, Ahmed M. El-Badwy, Graduted. - M.Sc. and Ph.D. thesis going on under my supervision: Ommya Ali, Mahmoud Omar, Neveen Elgendy, Amany Abdel-Kader, Eman Ismail, May Saleh.

Theses Examination Member of the Jury Committee for so many Msc. and Ph.D. theses Exams as e.g.: - Interaction of Ibuprofen, Phenytoin and paracetamol with cyclodextrin, M. Ahmed, Damascus, Syria, 1998. - Interac on of clonazepam with macrmolecules. Gamal M.R., Egypt, 1999. - Preparation and evaluation of sustained release tablets containing either Nitrofurantoin or Phanazopyridine hydrochloride , Adel M. Ali, Assiut, Egypt, 1992.

Memberships and other activities: - Biomedical Research, The Popula on Council, N.Y., USA, 1994. - Member in organizing committee for 1st Egyptian-Italian symposium,Egypt. - Member of Assiut university Staff Club. - Member of the Egyptian Syndicate in Cairo. - Member of ASIDA for infectious diseases, Cairo, Egypt.

LIST OF PUBLICATION

1. Ehab Elzayat , Ali A Abdel-Rahman, Sayed M Ahmed, Fars K Alanazi, Walid A

Habib, Adel Sakr, Studying the impact of formulation and processing parameters on the release characteristics from hydroxypropyl methylcellulose matrix tablets of diclofenac, Acta Poloniae Pharmaceutica 2, 2016….accepted for publication (Ref # 173-14)

2. Ehab M. Elzayat, Mohamed F. Ibrahim, Ali A. Abdel-Rahman, Sayed M. Ahmed, Fars K. Alanazi, Walid A. Habib, A validated stability-indicating UPLC method for determination of diclofenac sodium in its pure form and matrix formulations, Arabian Journal of Chemistry, 1-10 (2014)

3. H F Salem, M M Omar, S. M. Ahmed. Nanotheranostic liposomes for ocular delivery, J. controlled release, 2014.

4. S.M.Ahmed, Adel, A .Ali, Ahmed M. A. Ali, and Omiya, A. Hasan, Compatibility of Itopride HCl with certain formulation excipients, Unique J. pharm. Biolog. Sci. 1(3), 34-39 (2013).

5. S.M.Ahmed, Gamal Zayed, Contraceptive dosage forms, present and future, Unique J. pharm. Biolog. Sci. 1 (3): 1-10 (2013).

6. H M Tawfeek , S H Khidr, E M Samy, S M Ahmed, E E Gaskell, G A Hutcheon, Evaluation of biodegradable polyester-co-lactone micropar cles for protein delivery, Drug Dev. Ind. Pharm., 1-10, (2013).

7. H M Tawfeek and S.M.Ahmed, Molecular encapsulation of biologically activeglycolipids, Alex. J. Pharm. Sci. 26 (2), 67-74 (2012).

8. H M Tawfeek, S H Khidr, E M Samy, S M Ahmed, K Akram, A R Mohammed, G A Hutcheon, I Y Saleem, Pulmonary delivery of α-chymotrypsin via novel polyester microparticles. Journal of Pharmacy and Pharmacology, 62, (10), 1294-1295 (2012).

9. H M Tawfeek, S H Khidr, E M Samy, S M Ahmed, M. Murphy, A. Mohammed, A. Shabir, G A Hutcheon, I Saleem, Poly (glycerol adipate-co-ω-pentadecalactone) spray dried microparticles as sustained release carriers for pulmonary delivery. Pharm Research 28: 2086-2097 (2011).

10. H M Tawfeek, S H Khidr, E M Samy, S M Ahmed, G A Hutcheon, I Y Saleem, Effect of PEGylation on spray dried PGA-co-PDL pulmonary carrier microparticles. Journal of Aerosol Medicine and Pulmonary Drug Delivery, 24(6): 327 (2011).

11. H M Tawfeek , S H Khidr, E M Samy, S M Ahmed, A. Evans,E E Gaskell, G A Hutcheon, Encapsulation, release, bioactivity and cytotoxicity of lysozyme loaded microparticles. J. Pharm. and Pharmacol., 62, (10), , 1431-1432 (2010).

12. H M Tawfeek , S H Khidr, E M Samy, S M Ahmed, A. Evans,E E Gaskell, G A Hutcheon, Encapsulation, release, bioactivity and cytotoxicity of lysozyme loaded poly(glycerol adipte-co-ω-pentadecalactone) micropar cles. J. Pharm. and Pharmacol., 62, (10), , 1431-1432. (2010).

13. H M Tawfeek, S H Khidr, E M Samy, S M Ahmed, K Akram, A R Mohammed, E E Gaskell, G A Hutcheon, I Y Saleem, Optimisation of polyester based poly (glycerol adipte-co-ω-pentadecalactone) microparticles as carriers for pulmonary drug delivery. J. of Aerosol Medicine and Pulmonary Drug Delivery, 23(6): 430 (2010).

14. Ibrahim Alsara, Fars K. Alanazy, S.M. Ahmed, A. Bosela, Suliman Alhamad, Hammam Mowafy, and steven H. Neau, Comparative study of itraconazole- cyclodextrin inclusion complex and its commercial product, Arch Pharm. Res., 33 (7):1009-1017 (2010).

15. Fars K. Alanazy, S.M. Ahmed, S. Alhamad, and H. A. Mowafy, Ibrahim A. Alsarra, Mohsen A. Bayomi: Inclusion complexation of itraconazole with cyclodextrin derivatives: Phase solubility and physicochemical characterization. Mansura. J. of Pharm. Sci. 23 (2) 177-194 (2007).

16. I. Alsarra, F. Alanazy, S. Alhamad, S.M. Ahmed and H. Mowafy: Preparation and evaluation of itraconazole-cyclodextrin complexes in solid state. Alex. J. Pharm., 21 (1) 47- 59 (2007).

17. I. Alsara, M.O.Ahmed, M.Elbadry, F.Alanazy, A. Al-Mohizea, and S.M. Ahmed: Effect of β-cyclodextrin derivatives on the kinetics of degradation of cefotaxime sodium in solution state. J. drug Delivery Science &Technology, 17 (5) 353 (2007).

18. Fars K. Alanazi, S.M. Ahmed, Suliman S. Alhamed, Hammam A. Mowafy, I.A. Alsarra and Mohsen A. Bayomi: Inclusion complexation of itraconazole with cyclodextrin derivatives: Phase solubility and physicochemical characterization Mansoura J. Pharm. Sci.23, (2), 177 (2007).

19. S.M. Ahmed, H.A. Sarhan, M.A. Ibrahim and M.A. Amin: Formulation and characterization of biodegredable chitosan films for topical application of terbinafine HCL, Bull. Pharm. Sci. (Assiut Univ.) 30 (2), 111-129 (2007).

20. I.A. Alsarra, A.A. Bosela, S.M. Ahmed, G.M. Mahrous: Proneosomes as a drug carrier for transdermal delivery of ketrolac, Eur. J. Pharm and biopharmaceutics, 59, 485 (2005).

21. S. I. Saleh, S. H. Khidr, S. M. Ahmed, Theodore M. Jackniez, H.A. Nash; Estradiole/progesterone interaction during the preparation of vaginal rings, J. Pharm. Sci. 92 (2), 258 (2003).

22. E. Gadkariem, H. El-Obeid, M. Abounassif, S.M.Ahmed, K.Ibrahim: Effects of alkali and simulated gastric and intestinal fluids on danazole stability. J. Pharm. Biomed. Analysis, 31, 743 (2003).

23. M.I. Abdel-Rahman, M.O. Ahmed, S.M. Ahmed, T. Aboul- Fadl, A. El- Shaboury; Kinetics of solid state stability of glycine derivatives as a model for peptides using differen al scanning calorimetry, Biophysical Chemistry, 97,1, (2002).

24. S.A. Elkheshen, S.M. Ahmed, B.T. Al- Quadeib; Preparation and physicochemical characterization of piroxicam inclusion complexes with dimethyl and hydroxypropyl β-cyclodextrin in comparison with parent β-cyclodextrin, Die Pharm. Ind., 64(6), 612 (2002).

25. S.A. Elkheshen, S.M. Ahmed, B.T.Al- Quadeib; Inclusion complexes of piroxicam with β-CD deivatives in comparison with natural β-cyclodextrin, II- In-vitro and in-vivo drug availability. Die Pharm. Ind. 64 (6), 708 (2002).

26. A. Abdel Rahman; S.M Ahmed; and Mahrous G. Investigation of inclusion complexation for clonazepam with β- cyclodextrin and hydroxypropyl β-cyclodextrin in aqueous solutions and in solid states, Bull. Pharm. Sci., (2001).

27. M. O. Ahmed, I. El-Gebaly, S.M. Ahmed ; Effect of cyclodextrins on the physicochemical properties and antimycotic activity of clotrimazole, Int. J. Pharm. 171, 111 (1998).

28. S.M. Ahmed ; In vitro transfer, permeability and molecular complexation of a potent synthetic androgen, methyl nortestosterone acetate, compared with testosterone. Bull. Pharm. Sci. (Assiut Univ.). 20 (2), 169 (1997).

29. S.M. Ahmed; Effect of cyclodextrins on the chemical stability of ST1435, a contraceptive steroid progestin, in aqueous solution, J. Inclusion Phenomena, 27, 85 (1997).

28. S.M. Ahmed; Improvement of solubility and dissolu on of 19-norprogesterone, a potential contraceptive steroid, by inclusion complexation, J. Inclusion Phenomena, 30, 1 (1997).

29. L. Zhu; S.M. Ahmed; A.J. Moo-Young; C.W. Bardin, Comparative effects of LHRH agonist, Histrelin and LHRH antagonist, Azaline B on testicular function Proceedings-10th Int. Congress of Endocrinology, San Francisco, USA, (1996).

30. Mahrous O.; S.M. Ahmed; Saleh I. S.; Abdel Rahman, S.I., Complexation of hydrochlorothiazide and bendrofluazide with β-Cyclodextrin ground mixtures Saudi Pharm. J. 4(1), 23 (1996).

31. S.M. Ahmed; Arcuri, F.; Fang Li; Moo-Young, A.J.; Monder, C., Accelerated stability studies on 16-methylene- 17- acetoxy-19-nor-pregn-4- ene 3,20-dione (Nesterone), Steroids, 60, 534 (1995).

32. S.M. Ahmed; Casu, B.; Cedro, A.; Guerrini, M.; Lanzarotti, E.; Moltrasio, D.; Naggi, A; Torri, G., Disruption of micellar aggregates of ganglioside GM-1 by α-CD, Int. J. Pharm. 109, 99 (1994).

33. Saleh, S. I.; S.M. Ahmed; Mahrous O., Temazepam-cyclodextrin and temazepam-microcrystaline cellulose ground mixtures formulated into tablets, capsules and suppositories, Bull. Pharm. Sci. Assiut University, 17, 67 (1994).

34. S.M. Ahmed; A.E.; Abdel Rahman; Saleh, S. I.; Mahrous O., Comparative dissolution characteristics of bropirimine- β -cyclodextrin inclusion complex and its solid dispersion with PEG 6000. Int. J. Pharm. 96, 5(1993).

35. AM Aly, SI Saleh, SM Ahmed, SI Abdel-Rahman. Microencapsulation of nitrofurantion by coacervation using certain polymeric materials Bulletin of Pharmaceutical sciences, (1993).

36. AM Aly, S.M. Ahmed, SI Abdel-Rahman, SI Saleh - Sustained Release Formulations of Phenazopyridine Hydrochloride with Cellulose Acetate Phthalate Bulliten Pharm. Sc. (Assiut univ.) , (1993).

37. SM Ahmed, SI Saleh, SI Abdel-Rahman, SH Khidr: Preparation and release kinetics of ethylcellulose walled microcapsules containing phenazopyridine HCL dispersed in polymethymethacrylate matrices, STP Pharma sciences, (1992).

38. S.M Ahmed, Drug excipient physicochemical incompatibility studies involving temazepam, medazepam & lorazepam., Alex. Bull. Pharm. Sci., 6(2) 117, (1992).

39. S.M Ahmed ; Saleh, S.M. and Aboutaleb, A.E., Evaluation of tableted cinnarizine- microcrystalline cellulose ground mixtures. Bull. Pharm. Sci., (1992).

40. Prankerd, J.R. and S.M Ahmed , A study on physico-chemical interactions

involving praziquantel, oxamniquine and tablet excipients. J. Pharm. Pharmacol., 44, 259 (1992).

41. Prankerd, J.R. and S.M Ahmed , Physicochemical properties of oxamniquine indicate a new polymorphic form. J. Pharm. Pharmacol., 44, 261 (1992).

42. S.M Ahmed ; Saleh, S.I.; Abdel-Rahman, S.I.; Khidr, S.H.; Aboutaleb, A.E. and Ali, A.M.,Preparation and release kinetics of ethyl cellulose walled microcapsules containing phenazopyridine hydrochloride. STP-Pharma. Sci., 2 (2), 205 (1992).

43. Mulley, B.A.; Aboutaleb, A.E.; Abdel Rahman, A.A. and S.M Ahmed, Interactionof temazepam with hydro philic macromolecules.VIII- Effect of polyethylene glycol molecular weight and polysorbate 80 on temazepam dissolu on from solid dispersions. J. Pharm. Belg. 47, 141(1992)

44. S.M Ahmed ; Naggi, A.; Guerrini, M. and Focher, B., Inclusion complexes of bropirimine with β-cyclodextrin in solu on and the solid state. Int. J. Pharm.,77, 247 247 (1991).

45. Ali A. Abdel Rahman; Khidr, S.H.; S.M Ahmed and Aboutaleb, A.E., Evaluation of chloramphenicol -β- cyclodextrin inclusion complexes. Eur. J. Pharm. Biopharm. 37, 34 (1991).,,,,,,,,,,,,

46. Saleh, S.I.; S.M Ahmed and Aiache, J.M., Improvement of dissolution behavior of temazepam., Bull. Pharm. Sci., Assiut Univ., 14 (1,2) 95, (1991).

47. A. Abdel Rahman; Saleh, S.I.; S.M Ahmed; and Mahrous G. Preparation and evalua on of clonazepam solid dispersions. Bull. Pharm. Sci., Assiut Univ., 14, 49,(1991).

48. Saleh, S.I.; S.M Ahmed, and Aboutaleb, A.E., Dissolution behavior of cinnarizine from its ground mixtures with microcrystalline cellulose. S.T.P. Pharma, 5, 745 (1989).

49. Mulley, B.A.; Aboutaleb, A.E.; Abdel Rahman, A.A. and S.M Ahmed, Interaction of temazepam with certain macromolecules. VI- Preparation, dissolution characteristics and aging of temazepam solid dispersions. Bull. Pharm. Sci., Assiut Univ., 12, 175 (1989).

50. Mulley, B.A.; Aboutaleb, A.E.; Abdel Rahman, A.A. and S.M Ahmed, Interaction of temazepam with certain macromolecules.VII- Formulation of tablets containing temazepam solid dispersions. Bull. Pharm. Sci., (1989).

51. Mulley, B.A.; Aboutaleb, A.E.; Abdel Rahman, A.A. and S.M Ahmed, Interaction of temazepam with certain macromolecules. IV-Phase diagram of temazepam PEG binary systems. Bull. Pharm. Sci.(Assiut Univ.), 11, 50 (1988).

52. Mulley, B.A.; Aboutaleb, A.E.; Abdel Rahman, A.A. and S.M Ahmed, Interaction of temazepam with certain macromolecules. V- Thermodynamics of temazepam solubiliza on. Bull. Pharm. Sci., Assiut Univ., 11, 70 (1988).

53. Mulley, B.A.; Aboutaleb, A.E.; Abdel Rahman, A.A. and S.M Ahmed, Interaction of 1,4 benzodiazepines with certain macromolecules III- Wettability of modified temazepam crystals. Bull. Pharm. Sci., Assiut Univ., 9, 157 (1986).

54. Mulley, B.A.; Aboutaleb, A.E.; Abdel Rahman, A.A. and S.M Ahmed, Preformulation studies of directly compressed temazepam tablets, Bull. Pharm Sci., Assiut Univ. 9(2), 172(1986).

55. Aboutaleb, A.E.; Mulley, B.A.; Abdel Rahman, A.A. and S. M. Ahmed. Interac on of 1,4 benzodiazepines with macromolecules: I- Effect of non-ionic surfactants on the dissolution rate of temazepam. Bull. Pharm. Sci., Assiut Univ, 8(2), 158 (1985).

56. Mulley, B.A.; Aboutaleb, A.E.; Abdel Rahman, A.A. and S.M. Ahmed, Interac on of 1,4 benzodiazepines with certain macromolecules II- Crystallization of temazepam in presence of different hydrophilic macromolecules. Bull. Pharm. Sci., Assiut Univ., 8, 171 (1985).

57. Aboutaleb, A.E. and S.M. Ahmed, Solubilization of carbamazepine using cosolvents. Bull. Pharm. Sci., Assiut Univ., 6 (2), 310 (1983).

58. Aboutaleb, A.E. and S.M. Ahmed, Effect of temperature, pH and certain additives on the solubilization of carbamazepine by selected non-ionic surfactant solutions. Bull. Pharm. Sci., Assiut Univ., 6 (2), 123 (1983).

59. Aboutaleb, A.E. and S.M. Ahmed, A study on certain solubilized systems containing carbamazepine. Bull. Pharm. Sci., Assiut Univ., 6 (2), 335 (1983).

60. Aboutaleb, A.E. and , S. M. Ahmed. Solubilization of carbamazepine using hydrotropic agents. Bull. Pharm. Sci., Assiut Univ., 6 (2), 373 (1983).

Presentations and Abstracts in International and National conferences:

1. 2nd Int, Sokhna, Egypt, . Conference in basic and applied sciences, April 2014. 2. First workshop on Pham. Manufacturing and GMP, Nahda University, Feb 2014. 3. GMP, FUE international conference on pharm. sci , 2013, Cairo, Egypt. 4. QC/QA, FUE International workshop on modern tablet manufacturing,

Sci., 2013, Cairo, Egypt. 5. Use of natural products as poten al agents for fer lity control, 1 st

Int. conference on basic & applied science, 2013, Hurghada, Egypt. 6. Contraceptive methods present and future, ZTIPC conference in

pharm and clinical science, 2012, Al-Zaytoona Univ. Amman, Jordan. 7. H Tawfeek, S Khidr, E Samy, S.M. Ahmed, G Hutcheon, I Y Saleem, Effect of

PEGylation on spray dried PGA-co-PDL pulmonary carrier microparticles Drug Delivery to the lungs, DDL21, 2010, Int. Conf. Centre, Edinburgh, Scotland, UK.

8. H Tawfeek, S Khidr, E Samy, S.M. Ahmed, G Hutcheon, I Y Saleem, Enhancing the Aerosolisation Proprieties of poly(glycerol adipate-co-ω-pentadecalactone)

Microparticles as Novel Carriers for Dry Powder Inhalation. 37th Annual Meeting & Exposition of Controlled Release Soc.,2010, Oregon Convention, Portland, U.S. 1

9. H M Tawfeek, S H Khidr, E M Samy, S M Ahmed, E E Gaskell, G A Hutcheon Effect of different emulsifiers on the α-chymotrypsin loaded poly (propandioladipate-co-ω-pentadecalactone) microparticle characteristics. Institute for Health Research Annual Conference, 2010 , Albert Dock, Liverpool, UK.

10. H M Tawfeek, S H Khidr, E M Samy, S M Ahmed, E E Gaskell, G A Hutcheon, I. Saleem,PGA-co-PDL as a novel carrier for pulmonary drug delivery.The 7th World Meeting Pharmaceutical Technology, 2 010,MCC, La Valletta, Malta.

11. H M Tawfeek , S H Khidr, E M Samy, S M Ahmed, K Akram, A R Mohammed, E E Gaskell, G A Hutcheon, I Y Saleem, Optimisation of polyester based microparticles as carriers for pulmonary drug delivery. Drug Delivery to the lungs, DDL20, 2009, International Conference Centre, Edinburgh, Scotland, UK.

12. H M Tawfeek, S H Khidr, E M Samy, S M Ahmed, E E Gaskell, G A Hutcheon, Encapsulation and release of α-chymotrypsin using novel biodegradable polyesters, Institute H.R. Annual Conf. Liverpool, UK, 2009.

13. Hesham Tawfeek, Sayed Khidr, Eman Samy, , S M Ahmed Encapsulation and release of alpha-chemotrypsin in poly (glycerol adipate-co-omega- prentadeclactone) microparticles, 42nd IUPAC, 2009,Galsgow, Scotland, UK.

14. Formulation and development of gastroretentive drug delivery for sulpiride, 6th interna onal conf. of faculty of pharmacy, Assiut, Egypt, 2008.

15. Pharmaceutical applications of thermal analysis: Jordanian International Conference of Pharm. Sci., Alzaytoonah Univ. Jordan, 2006.

16. S. I. Abdel Rahman, S.M. Ahmed , E. M. Samy, A. Badawy, Improved formulation of lora dine tablets, 26 th Int. conf. of pharm. sciences, Cairo, Egypt, 1998.

17. Interac on of Quinidine with cyclodextrins, 26 th Int. conference of pharm. sciences, Cairo, Egypt, 1998.

18. Use of cyclodextrins to improve pharmaceutical properties of contracep ve steroids: The 37th mee ng of Syria, Damascus, Nov., 1997.

19. Improvement of solubility and dissolu on of 19-norprogesterone, a poten al contracep ve steroid, by inclusion complexa on, 1st International

20. Conference on Basic Sciences and Advanced Technology, Assiut, Egypt, 1996. 21. Preformulation studies on two antischistosomal drugs commonly used in Egypt,

1st Int. Conf. on Basic Sci. and Technology, Assiut, Egypt, 1996. 22. Sayed I. Abdel-Rahman, S.M. Ahmed; M. O. Ahmed, Improvement of solubility and dissolution of acetazolamide by inclusion complexation with different

cyclodextrins, XXV Interna onal conf. of pharm. sciences, Cairo,Egypt, 1996. 23. Molecular Encapsulation of biologically active glycolipids, XXV International

conference of pharm. sciences, Cairo, Egypt, 1996. 24. Comparative dissolution characteristics of bropirimine- β-cyclodextrin inclusion

complex and its solid dispersion with PEG 6000. 23rd Egyptian Pharm.conference, Cairo, Egypt, 1993.

25. S.M. Ahmed; and Aiache, Improvement of dissolution behavior of temazepam by cogrinding with β- cyclodextrin, hydroxypropyl-β-cyclodextrin, and microcrystalline cellulose. 23 rd Egyp an Pharm conf., Cairo, Egypt, 1993.

26. Modification of dissolu on of clonazepam. 23 rd Egyp an Pharm. conference, Cairo, Egypt, 1993.

27. Abdel Rahman, S.I.; S.M Ahmed ; Saleh, S.I.; Aboutaleb, A.E. and Aly, A.M.,Bioavailability of sustained release nitrofurantoin tablets prepared by 2 methods. 2nd Anglo-Egyp an conf. of Pharm. Sci., Alexandria, Egypt, (1992).

28. Sustained release formulations of phenazopyridine hydrochloride with cellulose acetate phthalate. Egyptian-Italian Symp. on Biotech., Assiut, Egypt, (1992).

29. Evaluation of tableted cinnarizine- microcrystalline cellulose ground mixtures. Presented at the second Anglo-Egyptian conference of Pharmaceutical sciences, Alexandria, Egypt (1991).

30. Drug excipient physicochemical incompatibility studies involving temazepam, medazepam and lorazepam., Presented at the second Anglo-Egyptian conference of Pharmaceu cal sciences, Alexandria, Egypt (1991).

31. Preparation and release characteristics of directly compressed sustained release tablets containing nitrofurantoin or phenazopyridine hydrochloride. 2nd Anglo-Egyp an conference of Pharmaceu cal sciences, Alex. , Egypt (1991).

32. Bioavailability of sustained release nitrofurantoin tablets prepared by two different methods. 2nd Anglo-Egyptian conference of Pharm. sci., Alexandria, Egypt (1991).

33. Formulation and release characteristics of some sustained release formulations of nitrofurantoin. 2nd Anglo-Egypt. Conf. of Pharm., Alexandria, Egypt (1991).

34. Naggi, A. ; S.M Ahmed; Cosentino, C. ; Focher, B. ; Guerrini, M. and Torri,G. Interactions of N-dodecyl--D-Maltoside and N-dodecyl- - D- Glucopyranoside with α-cyclodextrin in aqueous system. 6th European symposium on Carbohydrate, Edinburgh (Scotland), Sept. 1991, the Royal Society of Chemistry

35. S.M Ahmed; Casu, B. ; Cedro, A. ; Guerrini, M. ; Lanzarotti, E.; Naggi, A. and Torri, G., Monosialoganglioside -cyclodextrin inclusion complexes: Preparation and Characterization.The 6th European Symposium on Carbohydrate Chemistry, Edinburgh (Scotland), September 1991, Royal Society of Chemist. Ed.

36. Hesham Tawfeek, Sayed Khidr, Eman Samy, S.M. Ahmed, Encapsulation and release of alpha-chemotrypsin in poly (glycerol adipate-co-omega-prentadeclactone) micropar cles, 42nd IUPAC congress, Scotland UK, 2009.

References - Prof. Mahrous Osman: Vice dean of the faculty of pharmacy, Assiut University, Egypt. - Prof. Dr. Fathy Salama: Azhar University, Cairo, Egypt.

- Prof. Ahmed Bosela: Russian University, Cairo, Egypt.

- Dr. Hesham Tawfeek: Assiut university, Assiut, Egypt.

-Dr. Gamal Sultan: Azhar University, Cairo, Egypt.

- Dr. R. Prankerd: Senior Lecturer, Faculty of Pharmacy, Monash University, Australia.

- Prof. Dr. Ahmed Talat Nouh: Delta University, Mansoura, Egypt.