curriculum vitae robert c. burghardt, ph.d. june, … · curriculum vitae robert c. burghardt, ......
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CURRICULUM VITAE Robert C. Burghardt, Ph.D. June, 2016 PRESENT POSITION AND ADDRESS: Title: Professor of Veterinary Integrative Biosciences, Toxicology, Reproductive Biology, and Biotechnology Associate Dean for Research and Graduate Studies
Office: B.8E Vet. Med. Admin. Bldg. Phone: 979-847-8555 Email: [email protected]
EDUCATION: Degree/Training Conferring Institution Field Year B.S. University of Michigan Zoology 1969 M.S. Wayne State University Biology 1973 Ph.D. Wayne State University Biology 1976 Postdoctoral Harvard Medical School Reproductive Biology 1976-78 PROFESSIONAL EXPERIENCE AND ACADEMIC APPOINTMENTS:
2013 - Associate Dean for Research and Graduate Studies, College of Veterinary Medicine & Biomedical Sciences (CVM), Texas A&M University (TAMU)
1991 - Professor, Department of Veterinary Integrative Biosciences, TAMU, 1987 - Director, Image Analysis Laboratory, CVM, TAMU 1990- Member, Graduate Faculty, Texas A&M Health Science Center 1991 - Member, Interdisciplinary Faculty of Toxicology 2005 - 2010 Chair, Interdisciplinary Faculty of Toxicology 2010 - 2014 Vice chair, Interdisciplinary Faculty of Toxicology 1992 - Faculty, Center for Animal Biotechnology and Genomics 1998 - Member, Interdisciplinary Faculty of Reproductive Biology 2010 - 2012 Chair, Interdisciplinary Faculty of Reproductive Biology 2012 - Vice chair, Interdisciplinary Faculty of Reproductive Biology 2001 - Member, Interdisciplinary Faculty of Biotechnology 1999 - 2007 Associate Director, Center for Environmental and Rural Health, TAMU 1987 - 1991 Associate Professor, Department of Veterinary Anatomy and Public Health, TAMU 1984 - 1987 Associate Professor, Department of Biology, TAMU 1982 - 1987 Director, Electron Microscopy Center, TAMU 1978 - 1984 Assistant Professor, Department of Biology, TAMU 1977 - 1978 Instructor, Department of Anatomy, Harvard Medical School
AWARDS AND HONORS:
Ford Foundation Postdoctoral Fellowship, Laboratory of Reproduction and Reproductive Biology, Harvard Medical School, 1976-1978
Carrington Veterinary Medical Division Faculty Research Award in Cell Biology and Immunology, College of Veterinary Medicine, 1994
Association of Former Students, College of Veterinary Medicine Distinguished Teaching Award, 1995 Wiley Distinguished Teaching Professorship in Veterinary Medicine, 2000-2003 Vice Chancellor's Award in Excellence for Team Research in Uterine Biology and Pregnancy, 2005,
(Fuller Bazer, Robert Burghardt, Greg Johnson, Thomas Spencer and Guoyao Wu). Society for the Study of Reproduction Distinguished Service Award, 2010.
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EDITORIAL BOARDS:
Associate Editor, Biology of Reproduction, 1992-1995 Editorial Board Member, Cells, Tissues, Organs, 2004-present Editorial Board Member, Journal of Applied Toxicology, 2006-present Referring Editor, Biology of Reproduction: Responsible for editorial oversight for appeals to Editor-in-
Chief for contested decisions, 2001-2004.
GRANT REVIEW COMMITTEES:
National Science Foundation - Cell Biology Program, Ad hoc reviewer, March, 1986 - Physiological Processes Program, Ad hoc reviewer, March, 1991 - Signal Transduction and Regulation Program, Ad hoc reviewer, August, 1995. - Integrative Animal Biology Program, Ad hoc reviewer, September, 2001; October 2002;
March 2003 National Institutes of Health - Program Project Grant Review, Maternal and Child Health Research Committee,
National Institute of Child Health and Human Development, 9/26-28, 1990. Re-review of same Program Project Grant, 5/26/91.
- Biochemical Endocrinology Study Section, Child Health and Human Development, Pathophysiology of Endometriosis and Leiomyomata Uteri, Bethesda, MD, September 2-4, 1992.
- National Institute of General Medical Sciences, Special Emphasis Panel, MBRS Supplemental Instrumentation Grant Applications, Gaithersburg MD, April 30, 1996 - Temporary Member, Human Embryology and Development (HED-1) Study Section, October
21-22, 2002. - Temporary Member, Human Embryology and Development (HED-1) Study Section,
February 9-10, 2004. - Member, NIEHS Environmental Health Sciences Review Committee, site-visit team reviewing
NIEHS Center Grant Application, May 2-4, 2004. - Member, NIH/NIGMS MBRS ES SEP Review Committee, June 17-18, 2004. - Member, NIH, Special Study Section, Pregnancy & Perinatology, November, 2007 - Ad hoc reviewer, NIH/NIGMS, SCORE proposals, February 25-26, 2008. - Member, NIH/USDA PAR Study Section, Research Using Agriculturally Important Domestic
Species, March 21, 2011; March 27, 2012; March 26, 2013
National Cancer Institute, Role of the Microenvironment in Breast Cancer. February, 1994. Louisiana Education Quality Support Fund Research and Development Program. Ad hoc reviewer for
Board of Regents, January, 1992. Veterans Health Administration - Department of Veterans Affairs, Medical Research Service, Ad hoc reviewer, January, 1992. - Environmental Hazards Research Centers Review Committee, November-December, 1999. March of Dimes Birth Defects Foundation, Ad hoc reviewer, February, 1996. United States Department of Agriculture
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- Animal Reproductive Efficiency Program, National Research Initiative Competitive Grants Program, Ad hoc reviewer, April, 1994.
- Binational Agricultural Research Development (BARD) Program, Ad hoc reviewer, January, 1998
- Animal Reproductive Efficiency Program, USDA –CSREES National Research Initiative, Ad hoc reviewer, March, 1998, 1999, 2000, 2004
- Animal Reproductive Program, USDA –CSREES National Research Initiative, Ad hoc reviewer, January, 2008
Israel Science Foundation, administered by the Israel Academy of Sciences and Humanities, Ad hoc
reviewer, March 1993; April, 1998 Natural Sciences and Engineering Research Council of Canada, September, 2001 March of Dimes Central Texas Chapter, Grants Review Committee, 1999, 2000, 2001, 2002 Wellcome Trust, Joint Infrastructure Fund, UK. November, 1999. South Plains Foundation, July, 2002 Grant review for Pilot Interdisciplinary Research Projects from The BIO5 Institute, University of
Arizona, May, 2006. Internal reviews for TAMU Division of Research involving Limited Submission Proposals, 2013-2016
TEACHING EXPERIENCE: Since joining Texas A&M University in 1978, formal teaching responsibilities have been primarily at the graduate level and focused in areas of Cell Biology and evolving technologies associated with analytical electron and optical microscopy. From 1978 to 1987 my academic appointment was in the Department of Biology in the College of Science with an additional appointment from 1982 to 1987, as Director of the Electron Microscopy Center (Microscopy and Imaging Center) From 1978-1987 course responsibilities included: BIOL 602 Transmission Electron Microscopy BIOL 628 Scanning Electron Microscopy and X-ray Microanalysis BIOL 430 Biological Imaging BIOL 617 Cell Biology, Cell Signaling In 1987, I was appointed Associate Professor of Veterinary Anatomy and Director of the College of Veterinary Medicine Image Analysis Laboratory (IAL). Development of the IAL as a state-of-the-art optical microscopy laboratory with instrument and applications training in non-invasive cellular imaging has been a part of my teaching emphasis. Since 1987, I have also focused formal course offerings in Cell Biology (Cellular Signaling/Signal Transduction) and Optical Microscopy and Live Cell Imaging. Regular contributions are made to other team taught courses. Graduate Teaching responsibilities: Credit % of Formal Contact Hr Course Title Institution Hr Course Dates VIBS 617 Cell Signaling TAMU 1 hr 100% 15 1 hr lectures Every Fall
Semester 87-15
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ANSC 689 Reproductive Biology II TAMU 4 hr 6% 4hr Spring, 2004 BIOT 689 TAMU 1 hr 8% 1.5 hr lecture/lab Summer, 2002 PHEO/VAPH 605 Chemical Hazards Assessment TAMU 3 hr 5% 4 hr lecture/lab Fall, 2000, 2002, 2004, 2006, 2008 VMID 686 Scientific Ethics TAMU 2 hr 5% 2 hr Spring, 98-16 “Ethics of Scientific Imaging” VIBS 689/VIBS 627 Optical Microscopy & Live Cell Imaging 3 hr 100% 15 1.5 hr lectures Fall, 2009,
30 2 hr labs Every Spring 2010-16
Graduate Students*†: Advisor or Name Degree Institution Committee Member Dates Theodore Wing D.V.M. M.S. Chair 2013
Huajun He M.S Chair 2009 Dana Dean Ph.D. Co-Chair w CJ Welsh 2009 Lauri Willingham-RockyPh.D. Chair 2008 Zara Berg M.S Chair 2008 Saeed Al-Ramadan D.V.M., Ph.D. Chair 2007 Mindy Wiles Ph.D. Co-Chair w TD Phillips 2004 Jane Garlow M.S. Co-Chair w FW Bazer 2002 William Day Ph.D. Chair 1999 Richard Hutchinson D.V.M., Ph.D. Chair 1998
Catharine Schwab D.V.M., Ph.D. candidate. Chair (Deceased, 1996) Jeff Bowen Ph.D. Chair 1996 Jana Echols M.S. Chair 1995 Hugh Dookwah D.V.M., Ph.D. Chair 1993 Anton Hoffman, D.V.M., Ph.D. Chair 1992 Adelaide Brady Ph.D. Chair 1992 Michelle Aucoin D.V.M., Ph.D. Chair 1992
Lisa Stein Ph.D. Chair 1990 Mary L. Treat M.S. Chair 1986 Ruth E. Lewis Ph.D. Co-Chair 1985 Dana Gaddy M.S. Chair 1985 Philip A. Mitchell M.S. Chair 1985 Leslie L. McKenzie-Graham M.S. Chair 1982
†Current service as Committee Member on 3 active M.S. and 25 Ph.D. programs (9 different departments/interdisciplinary degrees):
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Name Department Degree Sought Sichao Jia Animal Science Ph.D. Candidate Rui Xu Biochemistry & Biophys. Ph.D. Candidate Kristina Najjar Biochemistry & Biophys. Ph.D. Candidate Helena Kondow Biochemistry & Biophys. Ph.D. Candidate William A. Cromwell Biomedical Sciences M.S. Candidate Richard Chang Biomedical Sciences Ph.D. Candidate Yang Gao Biomedical Sciences Ph.D. Candidate Cheng-An Chang Biomedical Sciences Ph.D. Candidate Shruti Gandhy Biomedical Sciences M.D., Ph.D. Candidate Benjamin Schwarz Biomedical Sciences Ph.D. Candidate Julia Popp Biomedical Sciences Ph.D. Candidate Ya-An Chang Biomedical Sciences Ph.D. Candidate Sarah M. Lane Chemistry M.S. Candidate Amanda David Chemistry Ph.D. Candidate Sayan Saha Chemistry Ph.D. Candidate Aaron Clubb Chemistry Ph.D. Candidate Dmitriy Verhhoturov Chemistry Ph.D. Candidate Camille Duran Genetics Ph.D. Candidate Yang Lee Medical Physiology Ph.D. Candidate Radhakrishna Pulikanti Physiol Reprod Ph.D. Candidate Jing Xu Physiol Reprod M.S.. Candidate Kirthiram Sivakumar Toxicology Ph.D. Candidate Leung Alvin Tang Toxicology Ph.D. Candidate Matthew Nemec Toxicology Ph.D. Candidate Robert Fuentes Toxicology Ph.D. Candidate Erik Hedrick Toxicology Ph.D. Candidate Sabrina Clark Veterinary Pathobiology Ph.D. Candidate Omar Khalaf Veterinary Pathobiology Ph.D. Candidate
*Additional service on over 260 completed Ph.D. and M.S. Degrees since 1979 (see page.38-43) Postdoctoral Fellows: Advisor or Name Committee Member Dates Michelle Aucoin Advisor NRSA 90-92 Tommy Sewall Advisor 96-98 Richard Hutchinson Advisor 97-98 Greg Johnson Co-Advisor 98-00 Igbal Awooda Advisor 00-02 Frankie White Co-Advisor 04-05 Jeffrey Catania Advisor 06-07 David Erikson Co-Advisor 07-10 Bryan White Co-Advisor 10-12 RESEARCH/SCHOLARLY ACTIVITIES: Current Research Support USDA, “The Role of Intraluteal Prostaglandins in Luteolysis and Luteal Protection in Sheep.” J.A. Arosh, PI, R.C. Burghardt, Collaborator, 9/1/13 to 8/31/17, $499,986, 5% effort. NIH/NIEHS, “Center for Translational Environmental Health Research,” C. Walker, PI, R.C. Burghardt,
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Advanced Imaging Core Director; Career Development Program Director, 04/01/14 to 3/31/17, $2,100,000, 10% effort. NIH/NIEHS, “Circadian Regulation of BaP Metabolism,” W. Porter, PI, R.C. Burghardt, Collaborator, 5/1/15 to 3/31/20, $1,739,169, 5% effort NIH/NICHD, “Role of miR15a and miR34c in PGE2 Signaling in the Pathogenesis of Endometriosis,” J.A. Arosh, PI, SK Banu, Co-PI, R..C. Burghardt, 5/1/15 to 3/31/20, $1,610,780, 5% effort DOD, “A New Paradigm for Ovarian Sex Cord-Stromal Tumor Development,” Q. Li, PI, R.C. Burghardt, Co-I, 4/15/15 to 4/14/17, $327,375, 5% effort NIH R21, “Characterization of a Novel Mouse Model with Enhanced TGF-Beta Signaling in the Ovary.” Q. Li, PI, R.C. Burghardt, Co-I, 7/1/15 to 6/30/17, $141,515, 5% effort. NSF-– Major Research Instrumentation, “MRI: Development of a Microfluidic Flow Cytometer for High-Throughput Noninvasive Single-Cell Physio-Chemical Analysis.” V.Yakovlev, PI, P. de Figueiredo, A. Han, M. Pishko, R. Burghardt, Co-PIs, 08/15/15-07/31/18, $710,564, 5% effort. Previous Support Federal Agencies
1. National Institutes of Health, Child Health and Human Development. (HD-14781). Intercellular Communication in the Mammalian Ovary. PI. 12/1/80 to 11/30/84. $228,468.
2. National Institutes of Health. Child Health and Human Development. (HD-26182). Structural and Functional Studies of Uterine Smooth Muscle Cells. PI. 9/1/89 to 8/30/93. $275,882.
3. United States Department of Agriculture. “Studies of Maternal Recognition of Pregnancy.” R.C. Burghardt, PI. 9/1/92 to 8/31/94, $165,950; - First Renewal of “Studies of Maternal Recognition of Pregnancy.” 9/1/94 to 8/31/97, $183,000; - Second Renewal of “Studies of Maternal Recognition of Pregnancy.” 9/1/98 to 8/31/02, $200,000. 4. United States Department of Agriculture. “Interferon Tau-induced Uterine Proteins Affect Peri-implantation Conceptuses.” F.W. Bazer, PI, R.C. Burghardt, Co-PI, 9/1/98 to 8/31/00, $233,000. 5. National Institutes of Environmental Health Science. "Center for Environmental and Rural Health" S.H. Safe, PI, R.C. Burghardt Associate Director. 04/01/02-03/31/07 $4,922,023 Total Center direct costs. R.C. Burghardt, Director of Image Analysis Core, 10% effort, annual funding for Image Analysis Core, $100,922. 6. United States Department of Agriculture, "Biological Functions of Galectin-15 in the Ovine Uterus." T.E. Spencer, PI, R.C. Burghardt, Co-PI, 10% effort, 7/01/05 to 6/30/08, $340,000. 7. NIH, “Age-Dependent Loss of N-Cadherin in Rat Proximal Tubules. Alan R. Parrish, PI, R.C. Burghardt and S.H. Safe, Co-Investigators, 5% effort, 6/1/05-4/30/08, $300,000. 8. National Institutes of Health. "Diet, Apoptosis and Colon Carcinogenesis." J.R. Lupton, PI, R. Chapkin, Co-PI, R.C. Burghardt, R. Carroll and N Turner, Co-Investigators, 5% effort, 4/01/01 to 1/30/06. $1,436,832. 9. National Institutes of Health, NIEHS. "Procedures to Assess the Hazards of a Superfund Site."
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Renewal: S.H. Safe, Director, R.C. Burghardt, Associate Director and Image Analysis Core Leader. 4/01/05 to 3/31/09, $3,400,000 Annual funding for Image Analysis Core, $65,000. 10. NIH, Bridges to the Doctorate in Reproductive Biology (BDRB) R25 GM075300. F.W. Bazer, PI; R.C. Burghardt and others, participating BDRB faculty. 9/01/06 to 8/31/09, $207,832 annual direct costs. 11. USDA, "Biological Functions of Galectin-15 in the Ovine Uterus." T.E. Spencer, PI, R.C. Burghardt, Co-I, 10% effort 7/01/05 to 6/30/09, $340,000. 12. NIH, “N-3 Fatty Acids Alter T-Cell Activation and Signaling.” R.S. Chapkin, PI, R.C. Burghardt, Co-I, 09/01/06 to 8/31/11, $1,250,000, 5% effort. 13. USDA, “Cellular Transport of Prostaglandins in Ovine Uterus. J. Arosh, PI, R.C. Burghardt, Collaborator, 01/06/2008 to 05/30/2011, $350,000, 5% effort. 14. NIH, “Effects of Lactational Exposure to Chromium VI on Ovarian Development,” Sakhila Banu, PI, RC Burghardt, Collaborator, 05/01/09 to 4/30/11, 5% effort. 15. NIH, “Endogenous Retroviruses in Conceptus Development and Placental Morphogenesis. T.E. Spencer, PI, R.C. Burghardt, Collaborator, 04/27/07 to 2/29/12, $1,250,000 direct, 5% effort 16. USDA, “Physiological Role of Prostaglandins and Interferon Tau in Conceptus Elongation and Endometrial Epithelial Function.” T.E. Spencer, PD, F.W. Bazer and R.C. Burghardt, Co-PDs. 10/7/09 to 10/6/12, $350,000, 5% effort. 17. NIH NICHD, “Molecular Basis of Treating Endometriosis by Prostaglandin E2 Receptor Inhibitors,” J. Arosh, PI, R.C. Burghardt, Collaborator, 9/25/2011 to 8/24/2013, $402,875. 18. NIH NICHD, “Prostaglandin E2 Signaling in Growth and Pains of Endometriosis.” J.A. Arosh, PI, R.C. Burghardt, Collaborator, 10/01/11 to 9/30/13, $402,875. 19. NIH NIEHS “Chromium VI-induced Toxicity on Female Reproductive Function.” S.K. Banu, PI, R.C. Burghardt, Collaborator, 8/6/11 to 7/31/13, $402,875. 20. NIH NCI, “MicroRNAs as Targets for Colon Cancer Chemotherapy.” S.H. Safe, PI, R.C. Burghardt, CoI, 6/30/09 to 4/30/14, $1,500,000, 5% effort. 21. NIH NIA, “Age-Dependent Nephrotoxicity Involves Loss of the N-cadherin/α-catenin Complex.” A.R. Parrish, PI, R.C. Burghardt, Co-I, 04/15/10 to 03/31/14,10% effort. 22. NIH NCI, “Molecular Mechanisms and Applications of Ah Receptor-MicroRNA Interactions,” S.H. Safe, PI, R.C. Burghardt, Co-I, 7/1/10 to 5/31/15, $1,609,735, 5% effort 23. DOD, (HBCU/MI), Partnership Training Award, Mandip Singh Sachdeva (Florida A&M University) and S.H.Safe, PIs, "The Role of Novel Substituted Diindolylmethane Analogues in the Treatment of Triple-Negative and ErbB2-Positive Breast Cancer" R.C. Burghardt and W. Porter Co-Mentors, 9/1/10 to 8/30/15, $1,400,000. 24. NIH NICHD, “Incorporation of Endothelial Progenitor Cells into Placental Vasculature.” G.A. Johnson, PI, R.C. Burghardt, Co-I, 2/1/13 to 1/31/15, $395,018, 5% effort.
Other Extramural Grant Support
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1. March of Dimes Birth Defects Foundation. Studies on the Cellular Basis for the Induction of Labor. Principal Investigator. 7/1/87 to 6/30/91. $90,000.
2. American Heart Association - Texas Affiliate. Cell-to-cell Communication Between Endothelial Cells. Principal Investigator. 7/1/89 to 12/30/90. $27,500.
3. NASA - Prairie View A&M Laboratory for Radiation Studies. “Effects of Ionizing Radiation on Cellular Toxicity of Caprine Uterine Epithelial Cells. G.R. Newton, PI, R.C. Burghardt & M. Walker, Co-PIs. 11/1/93 to 4/12/96. Subcontract to RCB, $20,000.
4. March of Dimes Birth Defects Foundation. Basic Research Grant, “Structural and Functional Analysis of Myometrial Gap Junctions.” R.C. Burghardt, PI. 7/1/95 to 6/30/99. $201,601.
5. Texas Equine Research Fund. “Persistent Endometritis and Myometrial Dysfunction in the Mare.” R.C. Burghardt and D.D. Varner, Co-PIs. 1/1/98 to 12/31/99. $47,940.
6. USDA Animal Health, “Myometrial Defects and Infectious Endometritis in Mares.” RC Burghardt, PI, 9/98 to 8/01. $48,900. 7. Bio-Arts and Research Corporation. “Cloning Adult Dogs by Nuclear Transfer.” M. Westhusin, PI, D.C. Kraemer and R.C. Burghardt, Co-PIs. 4/1/98 to 8/31/01. $3,513,684. 8. Grayson-Jockey Club and Research Foundation. “Myometrial Ca2+ Signaling in Mares with Persistent Endometritis. RC Burghardt, PI 4/1/99 to 3/31/01, $93,310.
Internal Research Support
1. Research Enhancement Funds, College of Veterinary Medicine. Analysis of a Cellular Oncogene and Cell-Cell Communication in Several Transformed Ovarian Cell Lines. Principal Investigator. 12/1/87 to 8/1/89. $6,936.
2. Texas Agricultural Experiment Station, Expanded Research Program. Cell-to-Cell Communication in Epithelial Cells: An In Vitro Assay for Cellular Toxicity. Principal Investigator. 8/1/89 to 7/31/91. $53,000.
3. Research Enhancement Funds, College of Veterinary Medicine. Multistep Carcinogenesis in Ovarian Cells. PI. 9/1/91 to 8/30/92. $18,500.
4. Institute of Equine Science and Technology Administered Research Enhancement Program Funds. A Model System for Studies of Maternal Recognition of Pregnancy in the Mare. PI. 12/1/91 to 8/31/93. $19,500.
5. USDA Animal Health Formula Funding. “The Cellular Basis for Antifertility Effects of Gossypol.” R.C. Burghardt, PI. 4/1/93 to 8/30/94. $35,000. 6. Texas Agricultural Experiment Station, Research Enhancement Program. “Mycotoxin-Induced Cellular Damage: Analysis of the Molecular Mechanisms of Damage and the Efficacy of Remediation by Chemisorbents. R.C. Burghardt, PI. 9/1/93 to 8/31/95. $79,804. 7. TAMU Associate Provost for Research and Graduate Studies, Interdisciplinary Research Initiatives. “The GT1 GnRH Neuronal Cell Line: A Model for Studying Calcium Involvement in GnRH Secretion.” Paul Harms, PI, R.C. Burghardt, Co-PI. 6/1/95 to 5/30/96. $25,000.
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8. Texas Racing Commission. “Reduced Uterine Muscle Contractility in Mares Susceptible to Persistent, Post Mating Endometritis - Is There a Structural Component to the Contractile Defect.” Sherri L. Rigby, PI, R.C. Burghardt and others Co-I. 9/00 to 8/01. $10,800 9. CVM Signature Program. “Implantation in Domestic Animals: Role of Integrins.” Laurie A. Jaeger, SP Brinsko, SL Rigby, RC Burghardt, FW Bazer, Co-PIs. 6/00 to 5/01. $54,000. 10. LSTF Proposal: “Genomic Basis of Human Environmental Disease.” S.H. Safe, PI, R.C. Burghardt, Image Analysis Core Director. 1/01/03 to 12/31/04, $467,320 for year 1; $39,000 for Image Analysis Core.
Equipment Grants
1. National Science Foundation. Biological Instrumentation Program. The Application of Transmission Electron Microscopy to Studies in Developmental and Cellular Biology. E.L. Thurston, PI, R.C. Burghardt, Co-PI. 10/15/79 to 1/31/81. $100,000.
2. Funding through Office of University Research Services for President's research incentive funding. Operational and equipment needs including upgrade of analytical microprobe and multi-personal computerization of the Texas A&M University Electron Microscopy Center operations. 3/28/83 to 8/31/83. $80,000.
3. Funding through Texas Agricultural Experiment Station for Program Development Funds. Contribution towards upgrade of light microscopy and image analysis capabilities of the Texas A&M University Electron Microscopy Center. 12/15/83 to 8/31/83. $15,000.
4. Funding through the Office of University Research Services, Texas Engineering Experiment Station, Texas Agricultural Experiment Station, College of Science, Department of Biology and Institute of Developmental Biology for the purchase of a SEM-IPS image analysis unit for the Electron Microscopy Center. 9/1/84 to 6/1/85, $60,000. 5. Center for Energy and Mineral Resources, Texas A&M University. Image Analysis System for Electron Microscopy. Principal Investigator. 5/16/84 to 5/31/85. $10,000.
6. Research Enhancement Funds, College of Veterinary Medicine. Application of Laser Cytometry for the Molecular Analysis of Cellular Regulation. Principal Investigator. 9/1/89 to 8/30/91. $150,000. This funding plus an additional $195,000 generated from other University sources was used to purchase a Meridian ACAS 570 Interactive Laser Cytometer for shared use in the College of Veterinary Medicine Image Analysis Laboratory.
7. NIH BRSG Small Instrumentation Grant Program. “Microinjection/Micromanipulator for Interactive Laser Cytometry Studies.” 9/1/91 to 8/31/92. $12,674. Institutional matching support Office of University Research, $8,600.
8. NIH Small Instrumentation Grants Program, “A Fluorescence Deconvolution Workstation.” 9/1/93 to 8/30/94. $39,802. Additional Institutional matching support obtained from the Texas Agricultural Experiment Station ($15,000), Office of University Research ($10,000), Department of Veterinary Anatomy & Public Health ($5,000), and College of Veterinary Medicine ($5,000).
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9. Institutional matching support for the purchase of Meridian Instruments, Inc. InSight Point video-rate fluorescence/confocal microscope. 3/1/96. $207,000. Contributions from Departments of Veterinary Anatomy & Public Health, Physiology & Pharmacology, Pathobiology, the College of Veterinary Medicine, Office of University Research, and Image Analysis Laboratory.
10. Texas Agricultural Experiment Station Faculty Research Development Program Infrastructure Award. “Image Analysis Workstation.” R.C. Burghardt, PI, 12/17/97 to 8/31/98. $40,000 plus $75,000 in matching support from Departments of Veterinary Anatomy & Public Health, Animal Science, and Image Analysis Laboratory.
11. College of Veterinary Medicine Signature Programs Enhancement Initiative. “Cellular and Tissue Imaging by Multiphoton Microscopy.” R.C. Burghardt and others. 3/99 to 4/01, $75,000. An additional $365,000 in matching support including funding provided from a grant thought the Dunn Foundation and contributions from 6 departments, the Office of Sponsored Programs, and the Texas Agricultural Experiment Station, Center for Environmental & Rural Health, Image Analysis Laboratory, and BioArts Research Corporation. 12. Institutional matching support for the purchase of a Zeiss - Stallion DDI high speed FRET and emission ratio calcium imaging system with Zeiss Apotome optical sectioning system. 2/15/05, $202,000. 13. Texas Agricultural Experiment Station, PUF Funds. 11/30/05. Acquisition of DIC for digital imaging workstation. $8,000 14. Center for Environmental and Rural Health. 3/31/06. Addition of lenses and heated stage for Zeiss Stallion DDI system. $26,000. 15. Various Institutional Funds totaling $198,723 to purchase Veritas Microdissection Instrument as trade-in/replacement of Arcturus Pixcell II Laser Capture Microdissection instrumentation. Quoted price $247,405 discounted to $198,723. Matching funds of $75,000 obtained from CVM Dean’s Office, CVM Departments VIBS, VTPP, VTPB, the Texas Agricultural Experiment Station, and Texas A&M Health Science Center and individual investigators (G Adams, FW Bazer, RC Burghardt, GA Johnson, WE Porter and TE Spencer). Balance of $123,723 provided by the Vice President for Research, 2007 16. National Institutes of Health, NCRR, 1S10RR22532-0, "Acquisition of a Confocal/ Multiphoton Microscopy System." R.C. Burghardt, PI, 6/1/06-5/30/07, $499,137. Additional institutional matching support of $231,000. 17. Texas Agricultural Experiment Station, PUF Funds. 12/06/07. Motorized stage for Zeiss 510 META NLO confocal microscope. $18,554, 2008 18. Various Institutional Funds totaling $284,000 for a Morgani 268 digital transmission electron microscope cost shared among CVM Departments VIBS $80K, VTPB $80K, CVM Deans Office $68K, VTPP $20K, LACS $10K, SACS $10K, Texas A&M Health Sciences Center, $10K, and the Animal Science Department $6K, and Image Analysis Laboratory, 2008 19. Various Institutional Funds totaling $258,184 for a Zeiss TIRF3 Microscope system, cost shared among VTPB, VIBS, ANSC, Texas AgriLife, IAL, CVM, and multiple individual investigators, 2009. 20. Texas A&M University, Office of the Vice President for Research totaling $1 million for a Zeiss Elyra S.1 super resolution microscope & Zeiss 789 NLO multiphoton microscope 34 channel spectral detection system, 2014.
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Teaching Grants
1. Center for Teaching Excellence, Incentive Grant, “Computer Based Self-instructional Aids for Microscopy and the Theory of Image Formation.” 4/1/00 to 3/31/01, $1,000.
2. Wiley Distinguished Teaching Professorship in Veterinary Medicine, 2000-2003 Basic Science Teaching Award, 9/1/00 to 8/30/03, $15,000. 3. AAA Outreach grant, Increasing Awareness and Use of Microscopy and Imaging by Veterinary Scientists,” American Association of Anatomists. LA Jaeger, PI, RC Burghardt, Co-PI, 2003-2004, $3,000.
PUBLICATIONS Refereed Journals: Google Scholar (all publications) https://scholar.google.com/citations?user=xDX1O9cAAAAJ&hl=en&oi=ao Scopus (1976-present) orcid ID http://orcid.org/0000-0003-1021-8444 Scopus ID: 7006709739; 9,263 citations, h-index 54 1. Burghardt RC, WE Foor (1975) Rapid morphological transformation of spermatozoa in the uterus of Brugia
pahangi (Nematoda, Filarioidea). J Parasit 61:343-350. 2. Burghardt RC, WE Foor (1978) Membrane fusion during spermiogenesis in Ascaris. J Ultrastruct Res
62:190-202. 3. Burghardt RC, E Anderson (1979) Hormonal modulation of ovarian interstitial cells with particular
reference to gap junctions. J Cell Biol 81:104-114. 4. Rizzo PJ, RC Burghardt (1980) Chromatin structure in the unicellular algae Olisthodiscus luteus,
Crypthecondinium cohnii and Peridinium balticum. Chromosoma 76:162-172. 5. Burghardt RC (1980) Intercellular junctions and exocytosis in the vas deferens of Ascaris. J Ultrastruct Res
71:162-172. 6. Burghardt RC, E Anderson (1981) Hormonal modulation of gap junctions in rat ovarian follicles. Cell
Tissue Res 214:181-193. 7. Lueking DR, TB Campbell, RC Burghardt (1981) Light induced division and genomic synchrony in
phototrophically growing cultures of Rhodopseudomanas sphaeroides. J Bact 146:790-797. 8. Rizzo PJ, RC Burghardt (1982) Histone-like protein and chromatin structure in the wall-less dinoflagellate
Gymnodinium nelsoni. BioSystems 15:27-34. 9. Burghardt RC, RL Matheson (1982) Gap junction amplification in rat ovarian granulosa cells. I. A direct
response to follicle stimulating hormone. Develop Biol 94:206-215. 10. Rizzo PJ, RC Burghardt (1983) Isolation of nuclei from the unicellular alga Olisthodiscus luteus
(Chloromonadophyceae). J Phycol 19:348-351. 11. Doucette GJ, RC Burghardt, GA Fryxell (1984) The genus Thalassiosira: Protoplast ultrastructure of the
bipolar diatom T. Antarctica Comber. Can J Bot 62:1513-1522. 12. Burghardt RC, R Matheson, D Gaddy (1984) Gap junction modulation in rat uterus. I. Effects of estrogens
on myometrial and serosal cells. Biol Reprod 30:239-248. 13. Burghardt RC, PA Mitchell, R. Kurten (1984) Gap junction modulation in rat uterus. II. Effects of
antiestrogens on myometrial and serosal cells. Biol Reprod 30:249-255. 14. Kurten RC, D Gaddy-Kurten, RC Burghardt (1985) Demonstration of occupied calcium- binding sites
associated with gap junction membrane by energy dispersive x-ray microanalysis. J Trace and Microprobe Techniques 3(4):303-325.
15. Mitchell PA, RC Burghardt (1986) The ontogeny of nexuses (gap junctions) in the ovary of the fetal mouse. Anat Rec 214(3):283-288.
16. Burghardt RC, D Gaddy-Kurten, RL Burghardt, RC Kurten, PA Mitchell (1987) Gap junction modulation in rat uterus. III. Structure-activity relationships of estrogen receptor-binding ligands on myometrial and serosal cells. Biol Reprod 36:741-751.
17. Stein LS, KA Neck, MS Frey, RC Burghardt (1989) Variable immunolabelling patterns of T-ag and p53 in a variety of SV40 transformed cell lines. TSEM Journal 20:13-15.
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18. Vempati RK, RH Loeppert, H Sittertz-Bhatkar, RC Burghardt (1990) Factors affecting infrared vibrations of hematite formed from aqueous- and dry-thermal incubations of Si-containing ferrihydrites. Clays and Clay Minerals 38:294-298.
19. Burghardt RC, JM Ehrman, TC Stephens, MF Hibbs, WL Bradley (1991) Measurement of microscopic displacements in graphite/epoxy composite materials using SEM-generated fiducial markers. Scanning 13:23-29.
20. Kim YR, DN Little, RC Burghardt (1991) SEM analysis on fracture and healing of sand-asphalt mixtures. J Materials in Civil Engineering 3:140-153.
21. Stein LS, G Stoica, R Tilley, RC Burghardt (1991) Rat ovarian granulosa cell culture: A model system for the study of cell-cell communication during multistep transformation. Cancer Res 51:696-706.
22. Pruitt JA, DW Forrest, RC Burghardt, JW Evans, DC Kraemer (1991) Viability and ultrastructure of equine embryos following culture in a static or dynamic system. J Reprod Fert, Suppl. 44:405-410.
23. Stein LS, JG Boonstra, RC Burghardt (1992) Reduced cell-cell communication between mitotic and nonmitotic coupled cells. Exp Cell Res 198:1-7.
24. Burghardt RC, R Barhoumi, EH Lewis, RH Bailey, KA Pyle, BA Clement, TD Phillips (1992) Patulin induced cellular toxicity: A vital fluorescence study. Tox Appl Pharmacol 112:235-244.
25. Stein LS, TH Welsh, Jr, VG Wilson, RC Burghardt (1992) Cell-cell communication competence in SV40 transfected rat ovarian granulosa cells (SV-GC) is reduced following tumor progression. In Vitro Cell Dev Biol 28A:436-444.
26. Dookwah HD, R Barhoumi, TK Narasimhan, SH Safe, RC Burghardt (1992) Gap junctions in myometrial cell cultures: Evidence for modulation by cAMP. Biol Reprod 47:397-406.
27. Brady HA, RC Burghardt, JW Evans, TL Blanchard, DD Varner (1992) Intercellular communication in mare endometrial epithelium isolated during estrus and diestrus. J Equine Vet Sci 12:227-232.
28. Ellington JE, DD Varner, RC Burghardt, VN Meyers-Wallen, R Barhoumi, SP Brinsko, BA Ball (1993) Cell-to-cell communication of equine uterine tube (oviduct) cells as determined by anchored cell analysis and sorting in culture. Anim Reprod Sci 30:313-324.
29. Legare ME, R Barhoumi, RC Burghardt, E Tiffany-Castiglioni (1993) Sensitive measurements of lead toxicity in cultured astroglia by interactive laser cytometry. Neurotoxicol 14:267-272.
30. Hoffman AG, RC Burghardt, R Tilley, N Auersperg (1993) An in vitro model of ovarian epithelial carcinogenesis: changes in cell-cell communication and adhesion occurring during neoplastic progression. Internat J Cancer 54:828-838.
31. Brady HA, RC Burghardt, JW Evans, TL Blanchard, DD Varner, JE Bruemmer (1993) Model system for the study of uterine/trophoblast interactions in the mare. J Equine Vet Sci 13(9):506-511.
32. Barhoumi R, JA Bowen, LS Stein, J Echols, RC Burghardt (1993) Concurrent analysis of intracellular glutathione content and gap junctional intercellular communication. Cytometry 14:747-756.
33. Burghardt RC, R Barhoumi, HD Dookwah (1993) Endocrine control of myometrial gap junctions and their control during parturition. Semin Reprod Endocrinol 11:250-260.
34. Stein LS, DWJ Stein, JE Echols, RC Burghardt (1993) Concomitant alteration of desmosomes, adhesiveness, and diffusion through gap junction channels in a rat ovarian transformation model system. Exp Cell Res 207:19-32.
35. Hanneman W, M Legare, R Barhoumi, R Burghardt, E Tiffany-Castiglioni, S Safe (1993) 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced elevation of intracellular calcium ions in cultured hippocampal neurons and astroglia. Organohalogen Compounds 13:353-356.
36. Fernandez P, R Burghardt, R Smith, K Nodland, S Safe (1994) High passage T47D human breast cancer cells: altered endocrine and 2,3,7,8-tetrachlorodibenzo-p-dioxin responsiveness. Eur J Pharmacol 270:53-65.
37. Moore M, X Wang, Y-F Lu, M Wormke, A Craig, JH Gerlach, R Burghardt, R Barhoumi, SH Safe (1994) Benzo[a]pyrene-resistant MCF-7 human breast cancer cells. J Biol Chem 269:11751-11759.
38. Danave IR, E Tiffany-Castiglioni, E Zenger, R Barhoumi, RC Burghardt, EW Collisson (1994) Feline immunodeficiency virus decreases cell-cell communication and mitochondrial membrane potential. J Virol 68:6745-6750.
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39. Sadhu DN, MS Lundberg, RC Burghardt, KS Ramos (1994) c-Ha-rasEJ transfection of rat aortic smooth muscle cells induces epidermal growth factor responsiveness and characteristics of a malignant phenotype. J Cell Physiol 161:490-500.
40. Zenger E, EW Collisson, R Barhoumi, RC Burghardt, E Tiffany-Castiglioni (1995) Laser cytometric analysis of FIV-induced injury in astroglia. Glia 13:92-100.
41. Barhoumi R, RH Bailey, RW Hutchinson, JA Bowen, RC Burghardt (1995) Enhancement of melphalan toxicity by octanol in ovarian adenocarcinoma cell lines: Effects of altered cell-cell communication, glutathione levels and plasma membrane fluidity. Fund Appl Toxicol 25:70-79.
42. Barhoumi R, RH Bailey, RC Burghardt (1995) Kinetic analysis of glutathione in anchored cells with monochlorobimane. Cytometry 19:226-234.
43. Aucoin MM, R Barhoumi, DT Kochevar, HJ Granger, RC Burghardt (1995) Oxidative injury of coronary venular endothelial cells depletes intracellular glutathione and induces HSP70 mRNA. Am J Physiol 268 (Heart Circ Physiol 37):H1651-1658.
44. Hutchinson RW, R Barhoumi, RC Burghardt (1995) Laser cytometric analysis of gossypol-induced cytotoxicity. Toxic Substance Mech 14:169-184.
45. Zhao F, K Mayura, RW Hutchinson, RP Lewis, RC Burghardt, TD Phillips (1995) Developmental toxicity and structure-activity relationships of chlorophenols using human embryonic palatal mesenchymal cells. Toxicology Letters 78:35-42.
46. Bao B, MG Thomas, MK Griffith, RC Burghardt, GL Williams (1995) Steroidogenic activity, insulin-like growth factor-1 production, and proliferation of granulosa and theca cells obtained from dominant preovulatory and non-ovulatory follicles during the bovine estrous cycle: effects of low-density and high-density lipoproteins. Biol Reprod 53:1271-1279.
47. Santos ECFD, DD Varner, RC Burghardt, DW Forrest, TL Blanchard (1995) Electrophoretic analysis of glycosaminoglycans from ovarian follicular fluid of mares. Biol Reprod Monograph 1:507-514.
48. Brady HA, TL Blanchard, JW Evans, DD Varner, W Day, CA Schwab, B Risek, NB Gilula, RC Burghardt (1995) Gap junction expression in equine endometrium. Biol Reprod Mono1:393-402.
49. Burghardt RC, Barhoumi R, Sewall T, Bowen J (1995) Cyclic AMP-induces rapid increases in gap junctional permeability and changes in the cellular distribution of connexin43. J Membr Biol 148:243-253.
50. Barhoumi R, RC Burghardt (1996) Kinetic analysis of the chronology of patulin- and gossypol-induced cytotoxicity in vitro. Fundam Appl Toxicol 30:290-297.
52. Burghardt RC, R Barhoumi, M Stickney, BM Sanborn, M Monga, CY Ku (1996) Correlation between connexin43 expression, cell-cell communication, and oxytocin-induced Ca2+-responses in an immortalized human myometrial cell line. Biol Reprod 55:433-438.
53. Bowen JA, GR Newton, DW Weise, F Bazer, RC Burghardt (1996) Characterization of a polarized porcine uterine epithelial cell model system. Biol Reprod 55:613-619.
54. Bowen JA, FW Bazer, RC Burghardt (1996) Spatial and temporal analyses of integrin and Muc-1 expression in porcine uterine epithelium and trophectoderm in vivo. Biol Reprod 55:1098-1106.
55. Hanneman WH, ME Legare, R Barhoumi, RC Burghardt, SH Safe, E Tiffany-Castiglioni (1996) Induction of calcium uptake in cultured rat hippocampal neurons by 2,3,7,8-tetrachlorodibenxo-p-dioxin (TCDD). Toxicology 112:19-28.
56. Barhoumi R, Y Mouneimne, TD Phillips, SH Safe, RC Burghardt (1996) Alteration of oxytocin-induced calcium oscillations in Clone 9 cells by toxin-exposure. Fundam Appl Toxicol 33:220-228.
57. Wang WL, W Porter, RC Burghardt, SH Safe (1997) Mechanism of inhibition of MDA-MB-468 cell growth by 2,3,7,8,-tetrachlorodibenzo-p-dioxin. Carcinogenesis 18:925-933.
58. Bowen JA, FW Bazer, RC Burghardt (1997) Spatial and temporal analyses of integrin and Muc-1 expression in porcine uterine epithelium and trophectoderm in vitro. Biol Reprod 56:409-415.
59. Zoran DL, R Barhoumi, RC Burghardt, RS Chapkin, JR Lupton (1997) Diet and carcinogen alter luminal butyrate concentration and intracellular pH of isolated rat colonocytes. Nutr &Cancer 27:222-230
60. Meola S, R Meola, R Barhoumi, J Miles, RC Burghardt (1997) Laser cytometric analysis of permethrin toxicity in insect and mammalian cells. Toxic Substance Mech 16:237-249.
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61. Wang WL, R Smith III, R Burghardt, SH Safe (1997) 17-estradiol-mediated growth inhibition of MDA-MB-468 cells stably transfected with the estrogen receptor: Cell cycle effects. Molec Cell Endocrinol 133:49-62.
62. Burghardt RC, JA Bowen, GR Newton, FW Bazer (1997) Extracellular matrix and the implantation cascade in pigs. J Reprod Fert Suppl 52:151-164.
63. Hoivik D, C Wilson, W Wang, K Willett, R Barhoumi, R Burghardt, S Safe (1997) Studies on the relationship between estrogen receptor content, glutathione S-transferase pi expression, and induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin and drug resistance in human breast cancer cells. Arch Biochem Biophys 348:174-182.
64. Thompson DC, R Barhoumi, RC Burghardt (1998) Comparative toxicity of eugenol and its quinone methide metabolite in cultured liver cells using kinetic fluorescence bioassays. Toxicol Appl Pharmacol 149: 55-63.
65. Day WE, JA Bowen, R Barhoumi, FW Bazer, RC Burghardt (1998) Endometrial connexin expression in the mare and pig: evidence for the suppression of cell-cell communication in uterine luminal epithelium. Anat Record 251:277-285.
66. Newton GR, DW Weise, JA Bowen, S Woldesenbet, RC Burghardt (1998) Regulation of protein and prostaglandin secretion in polarized primary cultures of caprine uterine epithelial cells. In Vitro Cell & Develop Biol 34:578-584.
67. Hutchinson RW, R Barhoumi, JM Miles, RC Burghardt (1998) Attenuation of gossypol cytotoxicity by cyclic AMP in a rat liver cell line. Toxicol Appl Pharmacol 151:311-318.
68. Ott TL, J Yin, AA Wiley, H-T Kim, B Gerami-Naini, TE Spencer, FF Bartol, RC Burghardt, FW Bazer (1998) Effects of the estrous cycle and early pregnancy on uterine expression of MX protein in sheep. Biol Reprod 59:784-794.
69. Parrish AR, RL Fisher, CM Bral, RC Burghardt, AJ Gandolfi, K Brendel, K Ramos (1998) Benzo(a)pyrene-induced alterations in growth-related gene expression and signaling in precision-cut adult rat liver slices. Toxicol Appl Pharmacol 152:302-308.
70. Legare, ME, R Barhoumi, E Hebert, GR Bratton, RC Burghardt, E Tiffany-Castiglioni (1998) Analysis of Pb2+ entry into cultured astroglia. Toxicol Sci 46:90-100.
71. Hutchinson RW, NH Ing, RC Burghardt (1998) Induction of c-fos and cytochrome C oxidase subunits I and II by gossypol acetic acid in a rat liver cell line. Cell Biol Toxicol 14:391-399.
72. Burghardt RC, R Barhoumi, BM Sanborn, J Andersen (1999) Oxytocin-induced Ca2+ responses in human myometrial cells. Biol Reprod 60:777-782.
73. Johnson GA, TE Spencer, TR Hansen, KJ Austin, RC Burghardt, FW Bazer (1999) Expression of the interferon tau inducible ubiquitin cross-reactive protein in the ovine uterus. Biol Reprod 61:312-318.
74. Mealey, KL R Barhoumi, RC Burghardt, BS McIntyre, PW Sylvester, H Hosick, DT Kochevar (1999) Immunosuppressant inhibition of P-glycoprotein function is independent of drug-induced suppression of peptide-prolyl isomerase and calcineurin activity. Cancer Chemotherapy and Pharmacology 44:152-158.
75. Fan YY, J Zhang, R Barhoumi, RC Burghardt, ND Turner, JR Lupton, RS Chapkin (1999) Antagonism of CD95 (APO-1/Fas) signaling blocks butyrate induction of apoptosis is colonic cells. Am J Physiol 277 (Cell Physiol 46) C310-319.
76. Johnson GA, TE Spencer, RC Burghardt, FW Bazer (1999) Ovine osteopontin I. Cloning and expression of ovine osteopontin mRNA in the uterus during the peri-implantation period. Biol Reprod 61:884-891.
77. Johnson GA, RC Burghardt, TE Spencer, GR Newton, TL Ott, FW Bazer (1999) Ovine osteopontin II. Osteopontin and v3 integrin expression in the ovine uterus and conceptus during the peri-implantation period. Biol Reprod 61:892-899.
78. Johnson GA, RC Burghardt, J-AGW Flemming, KM Taylor, GR Newton, FW Bazer, TE Spencer (1999) Development and characterization of immortalized ovine endometrial cell lines. Biol Reprod 61:1324-1330.
79. Gauntt C, D Busbee, HJ Wood, S Reyna, R Barhoumi, R Burghardt, B McAnalley, HR McDaniel (1999) A glyconutritional mixture (AmbrotoseR) provides some amelioration to mice with coxsackievirus-induced pancreatitis. Age 22:149-158.
80. Busbee D, C Gauntt, R Barhoumi, RC Burghardt, B McAnalley, HR McDaniel (1999) Protection from glutathione depletion by a glyconutritional mixture of saccharides. Age 22:159-165.
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81. Herrera P, RC Burghardt, TD Phillips (2000) Adsorption of Salmonella enteritidis by cetyl peridinium exchanged montmorillonite clays. Vet Microbiol 74:259-272.
82. Powell JK, SR Glasser, S Woldesenbet, RC Burghardt, GR Newton (2000) Expression of carbohydrate antigens in the goat uterus during early pregnancy and on steroid treated polarized uterine epithelial cells in vitro. Biol Reprod 62: 277-284.
83. Barhoumi R, Y Mouneimne, KS Ramos, SH Safe, TD Phillips, VE Centonze, C Ainley, MS Gupta, RC Burghardt (2000) Analysis of benzo[a]pyrene partitioning and cellular homeostasis in a rat liver cell line. Toxicol Sci 53:264-270.
84. Johnson GA, TE Spencer, RC Burghardt, MM Joyce, FW Bazer (2000) Interferon-tau and progesterone regulate expression of ubiquitin cross-reactive protein in the ovine uterus. Biol Reprod 62:622-627.
85. Alejandro NF, AR Parrish, RC Bowes III, RC Burghardt, KS Ramos (2000) Phenotypic profiles of cultured glomerular cells following repeated cycles of hydrocarbon injury. Kidney Internatl 57:1571-1580.
86. Johnson GA, TE Spencer, RC Burghardt, KM Taylor, CA Gray, FW Bazer (2000) Progesterone modulation of osteopontin gene expression in ovine uterus. Biol Reprod 62:1135-1140.
87. Stewart MD, GA Johnson, AG Gray, LA Schuler, RC Burghardt, FW Bazer, TE Spencer (2000) Prolactin receptor and UTMP expression in the ovine endometrium during the estrous cycle and pregnancy. Biol Reprod 62: 779-17789.
88. Bowen JA, RC Burghardt (2000) Cellular mechanisms of implantation in domestic farm animals. Semin Cell Develop Biol 11:93-104.
89. Hill JR, RC Burghardt, K Jones, CR Long, CR Looney, J Prior, T-Y Shin, TE Shin, TE Spencer, JA Thompson, QA Winger, ME Westhusin (2000). Evidence for placental abnormality as the major cause of mortality in first-trimester somatic cell cloned bovine fetuses Biol Reprod 63:1787-1794.
90. Combes GB, DD Varner, F Schroeder, RC Burghardt, TL Blanchard (2000) Effect of supplemental cholesterol on post-thaw motility and plasma membrane integrity of equine spermatozoa. J Reprod Fert Suppl 56:127-132.
91. Legare ME, WH Hanneman, R Barhoumi, RC Burghardt, E Tiffany-Castiglioni (2000) 2,3,7,8-tetrachlorodibenzo-p-dioxin alters hippocampal astroglia-neuronal gap junctional communication. Neurotoxicology 21:1109-1116.
92. Stewart DM, GA Johnson, CA Vyhlidal, RC Burghardt, SH Safe, L-Y Yu-Lee, FW Bazer, TE Spencer (2001) Interferon tau activates multiple STAT proteins and has complex effects on interferon-responsive gene transcription in ovine endometrial epithelial cells. Endocrinology 142:98-107.
93. Samudio I, C Vyhlidal, F Wang, M Stone, I Chen, M Kladde, R Barhoumi, R Burghardt S Safe (2001) Transcriptional activation of deoxyribonucleic acid polymerase alpha gene expression in MCF-7 cells by 17beta-estradiol Endocrinology 142:1000-1008.
94. Duan R, W Xie, R Burghardt, S Safe (2001) Estrogen receptor-mediated activation of the serum response element in MCF-7 cells through MAPK-dependent phosphorylation of Elk-1. J Biol Chem 276:11590-11598.
95. Johnson GA, D Stewart, CA Gray, Y Choi, RC Burghardt, L-Y Yu-Lee, J Chebath, FW Bazer, TE Spencer (2001) Effects of the estrous cycle, pregnancy and interferon tau on 2',5'-oligoadenylate synthetase expression in the ovine uterus. Biol Reprod 64:1392-1399.
96. Reeves WR, R Barhoumi, R Burghardt, SL Lemke, K Mayura, TD Phillips, KC Donnelly (2001) Evaluation of methods for predicting the toxicity of polycyclic aromatic hydrocarbon mixtures. Environ Sci Technol 35:1630-1636.
97. Westhusin ME, RC Burghardt, JN Rugila, LA Willingham, L Liu, T Shin, LM Howe (2001) Potential for cloning dogs. J Reprod Fert Suppl 57:287-293.
98. Hill JR, QA Winger, RC Burghardt, ME Westhusin (2001) Bovine nuclear transfer embryo development using cells derived from a cloned fetus. Animal Reprod Sci 67:17-26.
99. Rigby, SL, R Barhoumi, RC Burghardt, P Culleran, MK Wilkerson, DD Varner, TL Blanchard, SP Brinsko, T Taylor, MD Delp. (2001) Mares with delayed uterine clearance have an intrinsic defect in myometrial function. Biol Reprod 65:740-747.
100. Johnson GA, FW Bazer, LA Jaeger, H Ka, JE Garlow, C Pfarrer, TE Spencer, RC Burghardt (2001) Muc-1, integrin and osteopontin expression during the implantation cascade in sheep. Biol Reprod 65:820-828.
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101. Choi Y, GA Johnson, RC Burghardt, LR Berghman, MM Joyce, KM Taylor MD Stewart, FW Bazer, TE Spencer (2001) Epithelial expression of interferon regulatory factor two restricts expression of interferon-stimulated genes to the endometrial stroma and glandular epithelium of the ovine uterus. Biol Reprod 65: 1038-1049.
102. Washburn, KS, KC Donnelly, HJ Huebner, RC Burghardt, TC Sewall, LD Claxton. (2001) A study of 2,4,6-trinitrotoluene inhibition of benzo(a)pyrene uptake and activation in a microbial assay. Chemosphere.44:1703-1709.
103. Jaeger LA, GA Johnson, H Ka, JE Garlow, RC Burghardt, TE Spencer, FW Bazer (2001) Functional analysis of autocrine and paracrine signaling at the porcine uterine-conceptus interface. Reproduction Suppl., 58:191-207.
104. Mealey KL, R Barhoumi, RC Burghardt, S Safe, DT Kochevar (2002) Doxycycline-induced expression of P-glycoprotein in MCF-7 breast carcinoma cells. Antimicrob Agents Chemother 46:755-761.
105. Garlow JE, H Ka, GA Johnson, RC Burghardt, LA Jaeger, FW Bazer (2002) Analysis of osteopontin at the maternal-placental interface in pigs. Biol Reprod 66:718-725.
106. Cossio-Bayguar R, R Barhoumi, RC Burghardt, GG Wagner, PJ Holman (2002) Basal cellular alterations of esterase, glutathione, glutathione S-transferase, intracellular calcium and membrane potentials in Coumaphos resistant Boophilus microplus (Acari: Ixodidae) cell lines. Pesticide Biochem Physiol 72:1-9.
107. Chapkin R, MY Hong MY, Y-Y Fan, LA Davidson, LM Sanders, CE Henderson, R Barhoumi, RC Burghardt, ND Turner, JR Lupton (2002) Dietary n-3 polyunsaturated fatty acids alter colonocyte mitochondrial membrane composition and function. Lipids 37:193-199.
108. Choi YH, CC Love, YG Chung, DD Varner, ME Westhusin, RC Burghardt, K Hinrichs (2002) Production of nuclear transfer horse embryos by piezo-driven injection of somatic cell nuclei and activation with stallion sperm cytosolic extract. Biol Reprod 67:561-567.
109. Gray CA, RC Burghardt, GA Johnson, FW Bazer, TE Spencer (2002) Evidence that an absence of endometrial gland secretions in uterine gland knockout ewes compromises conceptus survival and elongation. Reproduction,124:289-300.
110. Qin C, T Nguyen, J Stewart, R Burghardt, S Safe (2002) Estrogen Up-regulation of p53 gene expression in MCF-7 breast cancer cells is mediated by calmodulin kinase IV-dependent activation of a nuclear factor kappaB/CCAAT-binding transcription factor-1 complex. Mol Endocrinol, 16:1793-809.
111. Barhoumi R, Y Mouneimne, I Awooda, SH Safe, KC Donnelly, RC Burghardt (2002) Characterization of calcium oscillations in normal and benzo[a]pyrene-treated Clone 9 cells. Tox Sci, 68: 444-450.
112. Abdelrahim M, I Samudio, R Smith, III, R Burghardt, S Safe (2002) Small inhibitory RNA duplexes for Sp1 mRNA block basal and estrogen-induced gene expression and cell cycle progression in MCF-7 breast cancer cells. J Biol Chem, 277:28815-28822.
113. Botos J, R Barhoumi, RC Burghardt, DT Kochevar (2002) Localization and kinetics of cell cycle-regulated RB phosphorylation in breast adenocarcinoma cells. Vitro Cell & Develop Biol, 38-235-241.
114. Stoner M, B Saville, M Wormke, D Dean, R Burghardt, S Safe (2002) Hypoxia induces proteasome-dependent degradation of estrogen receptor alpha in ZR-75 breast cancer cells. Mol Endocrinol, 16:2231-2242.
115. Hong MY, RS Chapkin, R Barhoumi, RC Burghardt, ND Turner, CE Henderson, LM Sanders, Y-Y Fan, LA Davidson, ME Murphy, CM Spinka, RJ Carroll, JR Lupton. (2002) Fish oil increases the mitochondrial phospholipid unsaturation, upregulating reactive oxygen species generation and apoptosis in rat colonocytes. Carcinogenesis, 23:1919-1925.
116. Burghardt RC, GA Johnson, LA Jaeger, H Ka, JE Garlow, TE Spencer, FW Bazer (2002) Integrins and extracellular matrix proteins at the maternal-fetal interface in domestic animals. Cells, Tissues, Organs 172:202-217.
117. Hong MS, SJ Hong, R Barhoumi, R Burghardt, KC Donnelly, JR Wild, V Venkatraj , E Tiffany-Castiglioni (2003) Neurotoxicity induced in differentiated SK-N-SH-SY5Y human neuroblastoma cells by organophosphorus compounds. Toxicol Appl Pharmacol, 186:110-118.
118. Wormke M, M Stoner, B Saville, K Walker, M Abdelrahim, R Burghardt, S Safe (2003) The aryl hydrocarbon receptor mediates degradation of estrogen receptor alpha through activation of proteasomes.
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Mol Cell Biol 23:1843-1855. 119. Qin C, R Burghardt, R Smith, M Wormke, J Stewart, S Safe (2003) Peroxisome proliferator-activated
receptor gamma agonists induce proteasome-dependent degradation of cyclin D1 and estrogen receptor alpha in MCF-7 breast cancer cells. Cancer Res 63:958-964.
120. Johnson GA, RC Burghardt, TE Spencer, FW Bazer, MM Joyce, C Pfarrer, CA Gray (2003) Osteopontin expression in uterine stroma indicates a decidualization-like differentiation during ovine pregnancy. Biol Reprod 68:1951-1958.
121. Johnson GA, RC Burghardt, MM Joyce, TE Spencer, FW Bazer, CA Gray, C Pfarrer (2003) Osteopontin is synthesized by uterine glands and a 45-kDa cleavage fragment is localized at the uterine-placental interface throughout ovine pregnancy. Biol Reprod 69:92-98.
122. Cizmas L, R Barhoumi, R Burghardt, W Reeves, L He, T McDonald, KC Donnelly (2003) A comparison of two methods for fractionating complex mixtures in preparation for toxicity analysis. J Toxicol Environ Health A. 66:1351-1370.
123. Johnson GA, RC Burghardt, FW Bazer, TE Spencer (2003) Osteopontin: Roles in implantation and placentation. Biol Reprod. 69:1458-1471.
124. Herrera P, R Burghardt, HJ Huebner, TD Phillips (2004) The efficacy of sand-immobilized organoclays as filtration materials for bacteria. Food Microbiol 21:1-10.
125. Spencer TE, GA Johnson, RC Burghardt, FW Bazer (2004) Progesterone and placental hormone actions on the uterus: Insights from domestic animals. Biol Reprod 71:2-10.
126. Sanders LM, CE Henderson, MY Hong, R Barhoumi, RC Burghardt, RJ Carroll, ND Turner, RS Chapkin, JR Lupton (2004) Pro-oxidant environment of the colon compared to the small intestine may contribute to greater cancer susceptibility. Cancer Letters 208:155-161.
127. Jiang J, D Dean, RC Burghardt, AR Parrish (2004) Disruption of cadherin/catenin expression, localization and interactions during HgCl2-induced acute renal failure. Toxicol Sci, 80:170-182.
128. Jung K-Y, D Dean, J Jiang, S Gaylor, RC Burghardt, WH Griffith, AR Parrish (2004) Selective loss of N Cadherin expression in proximal tubules in aging male Fischer 344 kidneys. Mech Ageing Dev 125:445-453.
129. Gray CA, DL Adelson, FW Bazer, RC Burghardt, EN Meeusen, TE Spencer (2004) Discovery and characterization of a novel epithelial-specific galectin in endometrium that forms crystals in trophectoderm. Proc Natl Acad Sci USA 101:7982-7987.
130. Li X, C Qin, R Burghardt, S Safe (2004) Hormonal regulation of lactate dehydrogenase-A through activation of protein kinase C pathways in MCF-7 breast cancer cells. Biochem Biophys Res Commun 320:625-634.
131. Spencer TE, RC Burghardt, GA Johnson, FW Bazer (2004) Conceptus signals for establishment and maintenance of pregnancy. Anim Reprod Sci 82-83:537-550.
132. Abdelrahim M, R Smith 3rd, R Burghardt, S Safe (2004) Role of Sp proteins in regulation of vascular endothelial growth factor expression and proliferation of pancreatic cancer cells. Cancer Res.64:6740-6749.
133. Sanders LM, CE Henderson, MY Hong, R Barhoumi, RC Burghardt, N Wang, CM Spinks, RJ Carroll, ND Turner, RS Chapkin, JR Lupton (2004) Enhancement of reactive oxygen species by dietary fish oil and attenuation of antioxidant defenses by dietary pectin coordinately heighten apoptosis in rat colonocytes. J Nutrition 134:3233-3238.
134. Spencer TE, GA Johnson, FW Bazer, RC Burghardt (2004) Implantation Mechanisms: Insights from the sheep. Reproduction 128:657-668.
135. Wu Q, R Burghardt, S Safe (2004) Vitamin D-interacting protein 205 (DRIP205) coactivation of estrogen receptor alpha (ERα) involves multiple domains of both proteins. J Biol Chem 279:53602-53612.
136. Joyce MM, FJ White, RC Burghardt, JJ Muniz, TE Spencer, FW Bazer, GA Johnson (2005) ISG15 conjugates to cytosolic proteins during the peri-implantation period and is expressed at the uterine-placental interface throughout pregnancy in sheep. Endocrinology 146:675-684.
137. Joyce MM, JF Gonzaleza, S Lewis, S Woldesenbet, RC Burghardt, GR Newton, GA Johnson (2005) Caprine uterine and placental osteopontin expression is distinct among epitheliochorial implanting
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species. Placenta 26:160-170. 138. Hayashi K, KD Carpenter, TH Welsh, Jr., RC Burghardt, LJ Spicer, TE Spencer (2005) The IGF system
in the developing neonatal ovine uterus. Reproduction 129:337-347. 139. Kim K, R Barhoumi, R Burghardt, S Safe (2005) Analysis of estrogen receptor α-SP1 interactions in
breast cancer cells by fluorescence resonance energy transfer. Mol Endocrinol 19:843-854. 140.Chintharlapalli S, R Burghardt, S Papineni, S Ramaiah, K Yoon, S Safe (2005) Activation of Nur77 by
selected 1,1-Bis(3'-indolyl)-1-(p-substitutedphenyl) methanes induces apoptosis through nuclear pathways. J Biol Chem 280:24903-24914.
141. Ottinger S, R. Barhoumi, K S McKenzie, T McDonald,R. Burghardt, TD Phillips (2005) FIA/MS analysis of temporally ozonated benzo[a]pyrene and pyrene and their reaction products inhibition of gap junction-mediated intercellular communication. Chemosphere 60:1025-1033.
142. Covington MD, KJ Bayless, RC Burghardt, GE Davis, AR Parrish (2005) Ischemia-induced cleavage of cadherins in NRK cells: evidence for a role of metalloproteinases. Am J Physiol Renal Physiol 289:280-288.
143. Gray CA, KA Dunlap, RC Burghardt, TE Spencer (2005) Galectin-15 in ovine uteroplacental tissues. Reproduction 130:231-240.
144. Jaeger LA, AK Spiegel, NH Ing, GA Johnson, FW Bazer, RC Burghardt (2005) Functional effects of transforming growth factor beta on adhesive properties of porcine trophectoderm. Endocrinology, 146:3933-3942.
145. White FW, JW Ross, MM Joyce, RD Geisert, RC Burghardt, GA Johnson (2005) Steroid regulation of cell specific osteopontin expression in the pregnant porcine uterus. Biol Reprod 73:1294-1301.
146. Zhang S, X Li, R Burghardt, R Smith 3rd, SH Safe (2005) Role of estrogen receptor (ER)α in insulin-like growth factor (IGF)-I-induced responses in MCF-7 breast cancer cells. J Mol Endocrinol 35:433-447.
147. Covington MD, RC Burghardt, AR Parrish (2005) Ischemia-induced cleavage of cadherins in NRK cells requires MT-1-MMP (MMP-14). Am J Physiol Renal Physiol, 290:F43-51.
148. Vanderlaag K, I Samudio, R Burghardt, R Barhoumi, S Safe (2005) Inhibition of breast cancer cell growth and induction of cell death by 1,1-bis(3'-indolyl)methane (DIM) and 5,5'-dibromoDIM. Cancer Lett 236:198-212.
149. Abdelrahim M, E Ariazi, K Kim, S Khan, R Barhoumi, R Burghardt, S Liu, D Hill, R Finnell, B Wlodarczyk, VC Jordan, S Safe (2006) 3-Methylcholanthrene and other aryl hydrocarbon receptor agonists directly activate estrogen receptor α. Cancer Res 66:2459-2467.
150. Muñiz JJ, MM Joyce, JD Taylor II, JR Burghardt, RC Burghardt, GA Johnson (2006) Glycosylation dependent cell adhesion molecule 1 (GLYCAM-1) and L-selectin expression in sheep interplacentomal and placentomal endometrium. Reproduction, 131:751-761.
151. Barhoumi R, I Awooda, Y Mouneimne, S Safe, RC Burghardt (2006) Effects of benzo-a-pyrene on oxytocin-induced Ca2+ oscillations in myometrial cells. Toxicol Lett 165:133-141.
152. Banerjee A, RC Burghardt, GA Johnson, FJ White, SK Ramaiah.(2006) The temporal expression of osteopontin (SPP-1) in the rodent model of alcoholic steatohepatitis: a potential biomarker. Toxicol Pathol 34:373-384.
153. Khan S, R Barhoumi, R Burghardt, S Liu, K Kim, S Safe (2006) Molecular mechanism of inhibitory aryl hydrocarbon receptor - estrogen receptor/Sp1 crosstalk in breast cancer cells. Mol Endocrinol 20:2199-2214.
154. Willingham-Rocky LA, MC Golding, JM Wright, DC Kraemer, ME Westhusin, RC Burghardt (2007) Cloning of GJA1 (Connexin43) and its expression in canine ovarian follicles throughout the estrous cycle. Gene Expression Patterns 7:66-71.
155. Dunlap KA, M Palmarini, M Verela, RC Burghardt, K Hayashi, JL Farmer, TE Spencer (2006) Endogenous retroviruses regulate peri-implantation placental growth and differentiation. Proc Natl Acad Sci U S A. 103:14390-14395.
156. White FJ, RC Burghardt, J Hu, MM Joyce, TE Spencer, GA Johnson (2006) Secreted phosphoprotein 1 (osteopontin) is induced by estrogen in mouse uterine lumenal epithelium during conceptus attachment for implantation. Reproduction 132:919-929.
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157. Spencer TE, GA Johnson, FW Bazer, RC Burghardt, M Palmarini (2007) Pregnancy recognition and conceptus implantation in domestic ruminants: roles of progesterone, interferons and endogenous retroviruses. Reprod Fertil Dev 19:65-78.
158. Westhusin ME, T Shin, JW Templeton, RC Burghardt, LG Adams (2007) Rescuing valuable genomes by animal cloning: A case for natural disease resistance in cattle. J Anim Sci 85:138-142.
159. Spencer TE, GA Johnson, FW Bazer, RC Burghardt (2007) Fetal-maternal interactions during the establishment of pregnancy in ruminants. Soc Reprod Fertil Suppl 64:379-396.
160. Barhoumi R, RC Burghardt, E Tiffany-Castiglioni (2007) Effects of propofol on intracellular Ca2+ homeostasis in human astrocytoma cells. Brain Res 1145:11-18.
161. Ka H, S Al-Ramadan, DW Erikson, GA Johnson, RC Burghardt, TE Spencer, LA Jaeger, FW Bazer (2007) Regulation of fibroblast growth factor-7 expression in the pig uterine endometrium by progesterone and estradiol. Biol Reprod 77:172-180.
162. Hayashi K, RC Burghardt, FW Bazer, TE Spencer (2007) WNTs in the Ovine uterus: potential regulation of peri-implantation ovine conceptus development. Endocrinology, 148:3496-3506.
163. Satterfield MC, KA Dunlap, K Hayashi, RC Burghardt, TE Spencer, FW Bazer (2007) Tight and adherens junctions in the ovine uterus: differential regulation by pregnancy and progesterone. Endocrinology 148:3922-3931.
164. Joyce MM, JR Burghardt, RC Burghardt, RN Hooper, LA Jaeger, TE Spencer, FW Bazer, GA Johnson (2007) Pig conceptuses increase uterine interferon regulatory factor-1 (IRF1), but restrict expression to the stroma through estrogen-induced IRF-2 in the luminal epithelium. Biol Reprod, 77:292-302.
165. Joyce MM, RD Geisert, JR Burghardt, RN Hooper, JW Ross, MD Ashworth, GA Johnson (2007) Pig conceptuses secrete estrogen and interferons to differentially regulate uterine STAT1 in a temporal and cell-type specific manner. Endocrinology, 148:4420-4431.
166. Chen G, EA Bridenbaugh, JM Catania, VS Vaidya, JV Bonventre, DC Zawieja, R.C. Burghardt, A.R. Parrish (2007) Increased susceptibility of aging kidney to ischemic injury: Identification of candidate genes changed during aging, but corrected by caloric restriction. Am J Physiol Renal Physiol, 293:F1272-F1281.
167. Chen G, Akintola A, Covington MD, Dean DD, Burghardt RC, Parrish AR (2007) Ischemia-induced cleavage of cadherins in NRK cells is not sufficient for beta-catenin transcriptional activity. Cell Commun Adhes 14:111-123.
168. Lewis SK, JL Farmer, RC Burghardt, GR Newton, GA Johnson, DL Adelson, FW Bazer, TE Spencer (2007). Galectin-15 (LGALS15): A gene uniquely expressed in the uterus of sheep and goats. Biol Reprod 77:127-1036.
169. Farmer JL, RC Burghardt, FD Jousan, PJ Hansen, FW Bazer, TE Spencer (2007) Galectin 15 (LGALS15) functions to promote trophectoderm migration and attachment. FASEB J 22:548-560.
170. Akintola AD, Z Crislip, JM Catania, G Chen, WE Zimmer R Burghardt, AR Parrish (2007) Promoter methylation is associated with the age-dependent loss of N-cadherin in the rat kidney. Am J Physiol Renal Physiol 294:F170-F176.
171. Laffin B, E Wellberg, H-I Kwak, RC Burghardt, RP Metz, T Gustafson, P Schedlin, WW Porter (2008) Loss of Single-minded-2s in the mouse mammary gland induces an epithelial mesenchymal transition associated with upregulation of SLUG and MMP2. Molec Cell Biol 26:1936-1946.
172. Kim J, G Song, H Gao, JL Farmer, MC Satterfield, RC Burghardt, G Wu, GA Johnson, TE Spencer, FW Bazer (2008) Insulin-like growth factor 2 (IGF2) activates PI3K-AKT1 and MAPK cell signaling pathways and stimulates proliferation and migration of ovine trophectoderm cells. Endocrinol 149:3085-3094.
173. Wu F, S Khan, Q Wu, R Barhoumi, R Burghardt, S Safe (2008) Ligand structure-dependent activation of estrogen receptor α / Sp by estrogens and xenoestrogens. J Ster Biochem Mol Biol 110:104-115.
174. Bruce E, R Autenrieth, R Burghardt, KC Donnelly, T McDonald (2008) Using quantitative structure-activity relationships (QSAR) to predict toxic endpoints for polycyclic aromatic hydrocarbons (PAH). J Toxicol Environ Health. A. 71:1073-1084.
175. Bridger PS, S Haupt, R Leiser, GA Johnson, RC Burghardt, H-R Tinneberg, C Pfarrer (2008) Integrin
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activation in bovine placentomes and in caruncular epithelial cells isolated from pregnant cows. Biol Reprod 79:274-282.
176. Banu SK, JB Samuel, JA Arosh, RC Burghardt, MM Aruldhas (2008) Lactational exposure to hexavalent chromium delays puberty by impairing ovarian development, steroidogenesis and pituitary hormone synthesis in developing Wistar rats. Toxicol Appl Pharmacol, 232:180-189.
177. Joyce MM, JR Burghardt, RC Burghardt, RN Hooper, FW Bazer, GA Johnson (2008) Uterine major histocompatibility Class I molecules and Beta 2 Microglobulin are regulated by progesterone and conceptus interferons during pig pregnancy. J Immunol, 181:2494–2505.
178. Dunlap KA, DW Erikson, RC Burghardt, FJ White, KM Reed, JL Farmer, TE Spencer, RR Magness, FW. Bazer, KJ Bayless, GA Johnson (2008) Progesterone and placentation increase secreted phosphoprotein one (SPP1 or osteopontin) in uterine glands and stroma for histotrophic and hematotrophic support of ovine pregnancy. Biol Reprod, 79:983-990.
179. Loudet A, J Han, R Barhoumi, J-P Pellois, RC Burghardt, K Burgess (2008) Non-covalent delivery of proteins into mammalian cells. Org Biomol Chem 6(24):4516-4522.
180. Song G, KA Dunlap, J Kim, DW Bailey, TE Spencer, RC Burghardt, GA Johnson, FW Bazer (2009) Stanniocalcin 1 is a luminal epithelial marker for implantation in pigs regulated by progesterone and estrogen. Endocrinology 150:936-950.
181. Bazer FW, RC Burghardt, GA Johnson, TE Spencer, G Wu (2008) Interferons and progesterone for establishment and maintenance of pregnancy: interactions among novel cell signaling pathways. Reprod Biol, 8:179-211.
182. Burghardt RC, JR Burghardt, JD Taylor II, AT Reeder, BT Nguen, GA Johnson (2009) Enhanced focal adhesion assembly reflects increased mechanosensation and mechanotransduction at the maternal/conceptus interface and uterine wall during pregnancy in sheep. Reproduction, 137:567-582.
183. Han J, A Loudet, RB Mouneimne, RC Burghardt, K Burgess (2009) A ratiometric pH reporter for observing protein-dye conjugates in living cells. J Am Chem Soc 131:1642-1643.
184. Barhoumi R, JM Catania, AR Parrish, I Awooda, E Tiffany-Castiglioni, S Safe, RC Burghardt (2009) Multiphoton spectral analysis of benzo[a]pyrene uptake and metabolism in breast epithelial cell lines. J Tox Sci 34:13-25.
185. Bruce E, R Autenrieth, R Burghardt, KC Donnelly, T McDonald (2009) Modeling toxic endpoints for improving human health risk assessment of polycyclic aromatic hydrocarbons (PAH) - parent compounds and simple mixtures. Toxicol Environ Chem.91:137-156.
186. Parrish AR, G Chen, RC Burghardt, T Watanabe, C Morisseau, BD Hammock (2009) Attenuation of cisplatin nephrotoxicity by an inhibitor of soluble epoxide hydrolase. Cell Biol Toxicol, 25:217-225.
187. Banu, SK, A Starzinski-Powitz, VO Speights, RC Burghardt, JA Arosh (2009) Induction of peritoneal endometriosis in nude mice using human immortalized endometriosis epithelial and stromal cells: A potential experimental tool to study molecular pathogenesis of endometriosis in human. Fertil Steril 91(5 Suppl):2199-2209.
188. Liu J, M Westhusin, G Johnson, T Raudsepp, B Chowdhary, R Burghardt, C Long, D Kraemer (2009) Evaluation of culture systems for attachment and proliferation of epithelial cells cultured from ovine semen. Animal Reprod Sci 115:49-57.
189. Banerjee A, R Rose, GA Johnson, RC Burghardt, SK Ramaiah (2009) The influence of estrogen on hepatobiliary osteopontin expression in a female rodent model of alcoholic steatohepatitis. J Toxicol Pathol 37:492-501.
190. Wu L, A Loudet, R Barhoumi, R Burghardt, K Burgess (2009) Fluorescent cassettes for monitoring three-component interactions in vitro and ex vivo. J Am Chem Soc 131: 9156-9157.
191. Papineni S, S Chintharlapalli, M Abdelrahim, SO Lee, R Burghardt, A Abudayyeh, C Bake, L Herrera, S Safe (2009) Tolfenamic acid inhibits esophageal cancer through repression of specificity proteins and c-met. Carcinogenesis 30: 1193-1201.
192. Figueriredo J, R Barhoumi, M Raffatellu, SD Lawhon, B Rousseau, RC Burghardt, RM Tsolis, AJ Bäumler, LG Adams (2009) Salmonella enterica serovar Typhimurium-induced internalization and IL-8 expression in HeLa cells does not have a direct relationship with intracellular Ca2+ levels. Microbes Infect
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11: 850-858. 193. Simmons RM, D Erikson, J Kim, RC Burghardt, FW. Bazer, GA Johnson, TE Spencer (2009) IGFBP1 is
a universal endometrial marker of conceptus elongation in the ruminant uterus and stimulates trophectoderm migration and attachment. Endocrinology 150: 4295-4305.
194. Bazer F, T Spencer, G Johnson, R Burghardt, G Wu (2009). Comparative aspects of implantation. Reproduction 138:195-209.
195. Barhoumi R, Y Qian, RC Burghardt, E Tiffany-Castiglioni (2010) Image analysis of Ca2+ signals as a basis for neurotoxicity assays: Promises and challenges. Neurotoxicol Teratol 32:16-24.
196. Erikson DW, RC. Burghardt, KJ Bayless, GA Johnson. (2009) Secreted phosphoprotein I (SPP1, osteopontin) binds to integrin alphavbeta6 on trophectoderm cells and integrin alphavbeta3 on uterine epithelial cells and promotes trophectoderm cell adhesion and migration. Biol Reprod 81:814-825.
197. Johnson GA, FW Bazer, RC Burghardt, TE Spencer, G Wu, KJ Bayless (2009) Conceptus-uterus interactions in pigs: endometrial gene expression in response to conceptus estrogen and interferons from conceptuses. Soc Reprod Fertil Suppl 66:321-332.
198. Bazer FW, H Gao, GA Johnson, G Wu, DW Bailey, RC Burghardt (2009) Select nutrients and glucose transporters in pig uteri and conceptuses. Soc Reprod Fertil Suppl 66:335-336.
199. Martinez JG, J Huang, RC Burghardt, R Barhoumi, RJ Carroll (2010) Use of multiple singular value decompositions to analyze complex intracellular calcium ion signals. Annal Appl Stat 3:1467-1492
200. Bazer FW, G Wu, TE Spencer, GA Johnson, RC Burghardt, K Bayless (2010) Novel pathways for implantation and establishment and maintenance of pregnancy in mammals. Mol Human Reprod 16:135-152.
201. Massuto DA, EC Kneese, GA Johnson, RC Burghardt, RN Hooper, NH Ing, LA Jaeger. (2010) Transforming growth factor beta (TGFB) signaling is activated during porcine implantation: Proposed role for latency associated peptide with integrins at the conceptus-maternal interface. Reproduction 139:465-478.
202. Wu G, FW Bazer, RC Burghardt, GA Johnson, SW Kim, X L Li, MC Satterfield, TE Spencer (2010) Impacts of amino acid nutrition on pregnancy outcome in pigs: mechanisms and implications for swine production. J An Sci 88(E.Suppl.) E195-204.
203. Dunlap KA, H-I Kwak, RC Burghardt, FW Bazer, RR Magness, GA Johnson, KJ Bayless (2010) The sphingosine-1-phosphate (S1P) signaling pathway is regulated during pregnancy in sheep. Biol Reprod 82:876-887.
204. Song G, DW Bailey, K Dunlap, RC Burghardt, TE Spencer, FW Bazer, GA Johnson (2010) Cathepsin B, cathepsin L and cystatin C in the porcine uterus and placenta: potential roles in endometrial/placental remodeling and in fluid-phase transport of proteins secreted by uterine epithelia, across placental areolae and neonatal gut. Biol Reprod 82:854-864.
205. Nunes J, SD Lawhon, CA Rossetti, S Khare, JF Figueiredo, T Gull, RC Burghardt, AJ Bäumler, RM Tsolis, HL Andrews-Polymenis, LG Adams (2010) Morphologic and cytokine profile characterization of Salmonella typhimurium infection in calves with bovine leukocyte adhesion deficiency. Vet Pathol 47:322-333.
206. Jose J, A Loudet, Y Ueno, R Barhoumi, RC Burghardt, K Burgess (2010) Intracellular imaging of organelles with new water-soluble benzophenoxazine dyes. Org Biomol Chem 8:2052-2059.
207. Li X, FW Bazer, GA Johnson, RC Burghardt, DW Erikson, JW Frank, TE Spencer, I Shinzato, G Wu (2010) Dietary supplementation with 0.8% L-arginine between days 0 and 25 of gestation reduces litter size in gilts. J Nutr 140:1111-1116.
208. Kim J, DW Erikson, RC Burghardt, TE Spencer, G Wu, KJ Bayless, GA Johnson, FW Bazer (2010) Secreted phosphoprotein 1 binds integrins to initiate multiple cell signaling pathways, including FRAP1/mTOR, to support attachment and force-generated migration of trophectoderm cells. Matrix Biol 29:369-382.
209. Chadalapaka G, I Jutooru, R Burghardt, S Safe (2010) Drugs that target specificity proteins downregulate epidermal growth factor receptor in bladder cancer cells. Mol Cancer Res 8:739-750.
210. Jutooru I, G Ghadalapaka, S Sreevslsan, P Lei, R Barhoumi, R Burghardt, S Safe (2010) Arsenic trioxide
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downregulation of specificity protein (Sp) transcription factors and inhibits bladder cancer cell and tumor growth. Exp Cell Res 316:2174-2188.
211. Black S, F Arnaud, RC Burghardt, MC Satterfield, JGW Fleming, C Long, C Hanna, L Murphy, R Biek, M Palmarini, TE Spencer (2010) Viral particles of endogenous betaretroviruses (enJSRVs) are released in the sheep uterus and potentially infect the conceptus trophectoderm in a trans-species embryo transfer model. J Virol 84;9078-9085.
212. Liu J, M Westhusin, C Long, G Johnson, R Burghardt, D Kraemer (2010) Embryo production and possible species preservation by nucleus transfer of somatic cells isolated from bovine semen. Theriogeniology 74:1629-1635.
213. Bailey DW, KA Dunlap, DW Erikson, A Patel, FW Bazer, RC Burghardt, GA Johnson (2010) Effects of long-term progesterone on developmental and functional aspects of porcine uterine epithelia and vasculature: progesterone alone does not support development of uterine glands comparable to that of pregnancy. Reproduction, 140:583-594.
214. Wu G, FW Bazer, RC Burghardt, GA Johnson, SW Kim, DA Knabe, P Li, XL Li, JR McKnight, MC Satterfield, TE Spencer (2011) Proline and hydroxyproline metabolism: implications for animal and human nutrition. Amino Acids 40:1053-1063.
215. Kim J, RC Burghardt, G Wu, GA Johnson, TE Spencer, FW Bazer (2011) Select nutrients in the ovine uterine lumen: VII. Effects of arginine, leucine, glutamine and glucose on cell signaling, proliferation and migration. Biol Reprod 84:62-69.
216. Kim J, RC Burghardt, G Wu, GA Johnson, TE Spencer, FW Bazer (2011) Select nutrients in the ovine uterine lumen: VIII. Arginine stimulates proliferation of ovine trophectoderm cells through mTOR-RPS6K-RPS6 signaling cascade and synthesis of nitric oxide and polyamines. Biol Reprod 84:70-78.
217. Vanderlaag K, Y Su, AE Frankel, RC Burghardt, R Barhoumi, G Chadalapaka, I Jutooru, S Safe (2010) 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes induce autophagic cell death in estrogen receptor negative breast cancer. BMC Cancer 2010, 10:669.
218. Bazer FW, TE Spencer, GA Johnson, RC Burghardt (2011) Uterine receptivity to implantation of blastocysts in mammals. Frontiers in Bioscience, S3:745-767, January 1, 2011.
219. Wu G, FW Bazer, GA Johnson, DA Knabe, RC Burghardt, TE Spencer, XL Li, JJ Wang (2011) Triennial Growth Symposium: Important roles for L-glutamine in swine nutrition and production. J An Sci 89:2017-2030.
220. Kim K, RC Burghardt, R. Barhoumi, S-O Lee, X Liu, S Safe (2011) Mdm2 regulates estrogen receptor alpha and estrogen-responsiveness in breast cancer cells. J Molec Endo 46:67-79.
221. Banu SK, JA Stanley, J Lee, SD Stephen, JA Arosh, PB Hoyer, RC Burghardt (2011) Hexavalent chromium-induced apoptosis of granulosa cells involves selective sub-cellular translocation of Bcl-2 members, ERK and p53. Toxicol Appl Pharmacol 251:253-266.
221. Kim J, RC Burghardt, G Wu, GA Johnson, TE Spencer, FW Bazer (2011) Select nutrients in the ovine uterine lumen: IX. Differential effects of arginine, leucine, glutamine, and glucose on interferon tau, ornithine decarboxylase and nitric oxide synthase in the ovine conceptus. Biol Reprod 84:1139-1147.
223. Loudet A, Y Ueno, L Wu, R Barhoumi, R Burghardt, K Burgess (2011) Organelle-selective energy transfer: as an indicator of intracellular environment. Bioorg Med Chem 21:1859-1851.
224. Barhoumi R, Y Mouneimne, E Ramos, C Morisseau, BD Hammock, S Safe, AR Parrish, RC Burghardt (2011) Multiphoton spectral analysis of benzo[a]pyrene uptake and metabolism in living cells. Toxicol Appl Pharmacol 253:45-56.
225. Jose J, A Loudet, Y Ueno, L Wu, H-Y Chen, DH Son R Barhoumi, R Burghardt, K Burgess (2011) Energy transfer cassettes in silica nanoparticles target intracellular organelles. Org Biomol Chem 9 3871-3877.
226. Stanley J, J Lee, TK Nithy, JA Arosh, RC Burghardt, SK Banu (2011) Chromium-VI arrests cell cycle and decreases granulosa cell proliferation by down-regulating cyclin-dependent kinases (CDK) and cyclins and up-regulating CDK-Inhibitors. Reprod Toxicol 32:112-123.
227. Kamkaew A, R Barhoumi, RC Burghardt, K Burgess (2011) Cationic polyfluorenes for intracellular delivery of proteins. Org Biomol Chem 9:6513-6518.
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228. Bazer FW, G Song, J Kim, D Erikson, GA Johnson, RC Burghardt, H Gao, MC Satterfirld, TE Spencer, G Wu (2011) Mechanistic Mammalian Target of Rapamycin (MTOR) cell signaling: Effects of select nutrients and secreted phosphoprotein 1 on development of mammalian conceptuses. Molec Cell Endocrinol 354:22-33.
229. Gardiner L, A Akintola, G Chen, J Catania, J Bonventre, V Vaidya, RC Burghardt, J Trzeciakowski, A Parrish (2012) Structural equation modeling (SEM) highlights kidney injury molecule (KIM-1) as a biomarker for chronic kidney disease. Am J Nephrol 35:152-163.
230. Kim K, I Jutooru, G Chadalapaka, G Johnson, J Frank, R Burghardt, S Safe (2012) HOTAIR is a negative prognostic factor and exhibits pro-oncogenic activity in pancreatic cancer. Oncogene. 32:1616-1625
231. Bazer FW, G Song, J Kim, KA Dunlap, MC Satterfield, GA Johnson, RC Burghardt, G Wu (2012) Uterine biology in pigs and sheep. J Anim Sci Biotech, 3:23 doi:10.1186/2049-1891-2-23.
232. Lee J, SK Banu, RC Burghardt, A Starzinski-Powitz, JA Arosh (2013) Selective inhibition of prostaglandin E2 receptors EP2 and EP4 inhibits adhesion of human endometriotic epithelial and stromal cells through suppression of integrin-mediated mechanisms. Biol Reprod, 88(3):77,1-11.
233. Stanley JA, KK Sivakumar, TK Nithy, JA Arosh, PB Hoyer, RC Burghardt, SK Banu (2013) Postnatal exposure to chromium through mother's milk accelerates follicular atresia in F1 offspring through increased oxidative stress and depletion of antioxidant enzymes. Free Radic Biol Med 61C:179-196.
234. Wu G, FW Bazer, MC Satterfield, X Li, X Wang, GA Johnson, RC Burghardt, Z Dai, J Wang, Z WU (2013) Impacts of arginine nutrition on embryonic and fetal development in mammals. Amino Acids 45: 241-256
235. Wu G, FW Bazer, GA Johnson, RC Burghardt, X Li, Z Dai, J Wang, G Wu (2013) Maternal and fetal amino acid metabolism in gestating sows. Soc Reprod Fertil Suppl 68:185-198.
236. Oelusarz A, LA Nichols, EA Grunz-Borgmann, G Chen, AD Akintola, JM Catania, RC Burghardt, JP Trzeciakowski, AR Parrish (2013) Overexpression of MMP-7 increases collagen 1A2 in the aging kidney. Physiol Rep, 1 (5), 2013, e00090, doi: 10.1002/phy2.90
237. Li X, FW Bazer, GA Johnson, RC Burghardt, X Li, JW Frank, Z Dai, J Wang, Z Wu, I Shinzato, G Wu (2013) Dietary supplementation with L-arginine between days 14 and 25 of gestation enhances embryonic development and survival in gilts. Amino Acids, 46:375-384.
238. Sivakumar KK, JA Stanley, JA Arosh, ME Pepling, RC Burghardt, SK Banu (2014) Prenatal exposure to chromium induces early reproductive senescence by increasing germ cell apoptosis and advancing germ cell cyst breakdown in the F1 offspring. Develop Biol 388:22-34.
239. Wang X, JW Frank, DR Little, KA Dunlap, MC Satterfield, RC Burghardt, TR Hansen, G Wu, FW Bazer (2014) Functional role of arginine during the peri-implantation period of pregnancy. I. Consequences of loss of function of arginine transporter SLC7A1 mRNA in ovine conceptus trophectoderm. FASEB J. 28:2852-2863.
240. Wang X, W Ying, KA Dunlap, G Lin, MC Satterfield, RC Burghardt, G Wu FW Bazer (2014) Arginine decarboxylase and agmatinase: an alternative pathway for de novo biosynthesis of polyamines for development of mammalian conceptuses. Biol Reprod 90(4):84,1-15.
241. Barhoumi R, Y Mouneimne, RS Chapkin, RC Burghardt (2014) Effects of fatty acids on benzo[a]pyrene uptake and metabolism in human lung adenocarcinoma A549 cells. PLoS One, 9(3):e90908. doi: 10.1371/journal.pone.0090908.
242. Jutooru I, AS Guthrie, G Chadalapaka, S Pathi, K Kim, R Burghardt, UH Jin (2014) Mechanism of action of phenethylisothiocyanate and other ROS-inducing anticancer agents. Mol Cell Biol 34:2382-2395.
243. Stanley JA, KK Sivakumar, JA Arosh, RC Burghardt, SK Banu (2014) Edaravone mitigates CRVI-induced oxidative stress and depletion of antioxidant enzymes while estrogen restores antioxidant enzymes in the ovary in F1 offspring. Biol Reprod, 91(1):12, 1–12.
244. Peña B, R Barhoumi, RC Burghardt, C Turro, KR Dunbar (2014) Confocal fluorescence microscopy studies of a fluorophore-labeled dirhodium compound: visualizing metal-metal bonded molecules in lung cancer (A549) cells. J Am Chem Soc 136:7861-7864.
245. Wang X, JW Frank, J Xu, KA Dunlap, MC Satterfield, RC Burghardt, TR Hansen, G Wu, FW Bazer (2014) Functional role of arginine during the peri-implantation period of pregnancy. II. Consequences of
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loss of function of nitric oxide synthase NOS3 mRNA in ovine conceptus trophectoderm. Biol Reprod 91(3):59,1-10.
246. Johnson GA, Burghardt RC, Bazer FW (2014) Osteopontin: A leading candidate adhesion molecule for implantation in pigs and sheep. J Anim Sci Biotechnol 2014 Dec 17;5(1):56.
247. Zhu C, Z Jiang, FW Bazer, GA Johnson, RC Burghardt, G Wu (2015) Aquaporins in the female reproductive system of mammals. Front Biosci (Landmark Ed). 20:838-871.
248. Gao Y, S Duran, JP Lydon, FJ DeMayo, RC Burghardt, KJ Bayless, L Bartholin, Q Li (2015) Constitutive activation of transforming growth factor beta receptor 1 in the mouse uterus impairs uterine morphology and function. Biol Reprod 92(2):34 1–13.
249. Ruiz-Gonzalez I, J Xu, X Wang, RC Burghardt, KA Dunalp, FW Bazer (2015) Exosomes, endogenous retroviruses and toll-like receptors: Pregnancy recognition in ewes. Reproduction, 149(3):281-291.
250. Wang X, GA Johnson, RC Burghardt, G Wu, FW Bazer (2015) Uterine histotroph and conceptus development. I. Cooperative effects of arginine and secreted phosphoprotein 1 on proliferation of ovine trophectoderm cells via activation of the PDK1-Akt/PKB-TSC2-MTORC1 signaling cascade. Biol Reprod 92(2):51, 1–10.
251. Banu SK, JA Stanley, KK Sivakumar, JA Arosh, R Barhoumi, RC Burghardt (2015) Identifying a novel role for X-prolyl Aminopeptidase (Xpnpep)2 in CrVI-induced adverse effects on germ cell nest breakdown and follicle development. Biol Reprod 92(3):67, 1-18.
252. Wang X, RC Burghardt, JJ Romero, TR Hansen, G Wu, FW Bazer (2015) Functional roles of arginine during the peri-implantation period of pregnancy. III. Arginine stimulates proliferation and interferon tau production by ovine trophectoderm cells via nitric oxide and polyamine-TSC2-MTOR signaling pathways. Biol Reprod 92(3):75, 1–17
253. Ma X, S. Dahanayaka, MC Satterfield, R Burghardt, FW Bazer, G Wu (2015) Technical note: Isolation and characterization of ovine brown adipocyte precursor cells. J An Sci 93(5):2094-2099.
254. Arosh J, J Lee, D Balasubbramanian, JA Stanley, CR Long, M Meagher, KG Osteen4 KL Bruner-Tran, RC Burghardt, A Starzinski-Powitz, SK Banu (2015) Molecular and preclinical basis to inhibit PGE2 receptors EP2 and EP4 as a novel nonsteroidal therapy for endometriosis. Proc Natl Acad Sci U S A. 112(31):9716-9721.
255. Stanley JA, JA Arosh, RC Burghardt, SK Banu (2015) A fetal whole ovarian culture model for the evaluation of CrVI-induced developmental toxicity during germ cell nest breakdown. Toxicol Appl Pharmacol 289:58-69.
256. Geisert RD, GA Johnson, RC Burghardt (2015) Implantation and establishment of pregnancy in the pig. Adv Anat Embryol Cell Biol. 2015;216:137-163.
257. Dahanayaka S, R Rezaei, WW Porter, GA Johnson, RC Burghardt, FW Bazer, YQ Wu, G Wu (2015) Technical note: Isolation and characterization of porcine mammary epithelial cells. J An Sci, 93(5):2094-2099.
258. Banu SK, Stanley JA, Sivakumar KK, Arosh JA, Burghardt RC (2016) Resveratrol protects the ovary against chromium-toxicity by enhancing endogenous antioxidant enzymes and inhibiting metabolic clearance of estradiol. Toxicol Appl Pharmacol 303:65-78.
Book Chapters:
1. Burghardt RC, WH Fletcher (1990) Physiologic roles of gap junctional communication in reproduction. In: UTERINE FUNCTION: Molecular and Cellular Aspects (M. Carsden and R. Miller eds.), Plenum Publ., New York. pp. 277-313.
2. Burghardt RC, R Barhoumi, D Doolitte, TD Phillips (1994) Application of Cellular Fluorescence Imaging for In Vitro Toxicology Testing. In: Principles and Methods of Toxicology, 3rd Edition, AW Hayes, Ed. Raven Press, New York. pp 1231-1259.
3. Tiffany-Castiglioni E, ME Legare, LA Schneider, ED Harris, R Barhoumi, J Zmudzki, Y Qian, RC Burghardt (1996) Heavy Metal Effects in Glia. In: Paradigms of Neural Injury (J R Perez-Polo, Ed. Methods in Neurosciences, Volume 30, Academic Press, San Diego. pp 135-166.
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4. Burghardt RC, J Bowen, FW Bazer (1998) Endocrine Control of Trophoblast-Uterine Epithelial Cell Interactions. In: Contemporary Endocrinology: Endocrinology of Pregnancy. FW Bazer, ed., Humana Press pp. 199-228.
5. Burghardt RC, R Droleskey (2006) Transmission Electron Microscopy. In: Current Protocols in Microbiology, John Wiley and Sons, Inc., 2.0.1-2.0.2. 39 pp.
6. Spencer TE, FW Bazer, GA Johnson, M Palmarini, RC Burghardt (2007) Fetal-maternal interactions during the establishment of pregnancy in ruminants. In: Reproduction in Domestic Ruminants VI. pp 379-396. Edited by JI Juengel, JF Murray and MF Smith. Nottingham University Press, Nottingham, UK.
7. Wu G, FW Bazer, RC Burghardt GA Johnson, SW Kim, DA Knabe, Xilong Li, MC Satterfield, SB Smith, TE Spencer (2010) Functional amino acids in swine nutrition and production. In: Dynamics in Animal Nutrition, (J. Doppenberg and P. van der Aar, eds.) Wageningemn Academic Publishers, pp 69-98.
8. Geisert RD, GA Johnson, RC Burghardt (2015) Implantation and establishment of pregnancy in the pig. In: Regulation of Implantation and Establishment of Pregnancy in Mammals. Tribute to 45 Year Anniversary of Roger V. Short's "Maternal Recognition of Pregnancy" Springer International Publishing. Adv Anat Embryol Cell Biol. 2015;216:137-163.
Refereed Proceedings/Monographs:
1. Fitz TA, RC Burghardt, MM Marr, TL Walden, CA Winkel (1989) Intercellular communication among SV40-transformed rat granulosa cells may be an index of differentiation. In: Eicosanoids and Other Bioactive Lipids in Cancer and Radiation Injury. (KV Honn, LJ Marnett, S Nigam, TL Walden, Jr, eds,), Kluwer Publ., Boston. pp. 363-367.
2. Burghardt RC, JM Ehrman, TC Stephens, and MF Hibbs (1990) Measurement of microscopic displacements in graphite/epoxy composite materials using a SEM-generated surface map. Proceedings of the XIIth International Congress for Electron Microscopy. Vol. IV, pp. 430-431.
3. Tuttle KL, JW Evans, DW Forrest, RC Burghardt (1991) Immunohistochemical localization of luteinizing hormone receptors in equine ovarian follicles. J. Reprod. Fert. Proceedings of the 5th International Symposium on Equine Reproduction. p. 635-636.
4. Pruitt JA, DW Forrest, RC Burghardt, JW Evans, DC Kraemer (1991) Viability and ultrastructure of equine embryos following culture in a static or dynamic system. J. Reprod. Fert. Proceedings of the 5th International Symposium on Equine Reproduction. pp 405-410.
5. Santos ECFD, DD Varner, RC Burghardt, DW Forrest, TL Blanchard (1995) Electrophoretic analysis of glycosaminoglycans from ovarian follicular fluid of mares. Biol Reprod Monograph 1:507-514.
6. Brady HA, TL Blanchard, JW Evans, DD Varner, W Day, CA Schwab, B Risek, NB Gilula, RC Burghardt (1995) Gap junction expression in equine endometrium. Biol Reprod Mono 1:393-402.
7. Burghardt RC, R Barhoumi Mouneimne, MA Walker, GR Newton (1996) Development of laser cytometric approaches to analyze cellular toxicity mechanisms induced by ionizing radiation. Radiation Studies Conference Proceedings, RADSCON’96, pp 82-86.
8. Burghardt RC, R Barhoumi (1997) Analysis of mechanisms of cellular injury on the micrometer scale. Microscopy and Microanalysis, Vol 3, Suppl 2, Proceedings: Microscopy and Microanalysis ‘97, pp 37-38.
9. Barhoumi R, RC Burghardt, DL Busbee, HR McDaniel (1997) Enhancement of glutathione levels and protection from chemically initiated glutathione depletion in rat liver cells by glyconutritionals. Proceedings of the Fisher Institute for Medical Research, Vol 1, No 1, November 1997. 5 pp.
10. Wilson CL, R Barhoumi, R Burghardt, A Miladi, A Jung (2000) Effects of JP-8 jet fuel on homeostasis of Clone 9 rat liver cells. JANNAF 18th Safety and Environmental Protection Subcommittee Meeting, 123-129. NASA Technical Reports Server.
11. Al-Ramadan S, SP Brinsko, LA Jaeger, SL Rigby, RC Burghardt (2002) Analysis of MUC-1 and integrin subunit expression in equine uterine epithelium and trophectoderm. Theriogenology, 58(2-4):829-832. Equine Reproduction VIII - Proceedings of the Eighth International Symposium on Equine Reproduction, Fort Collins, USA, July 2002
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12. Bazer FW, GA Johnson, RC Burghardt (2004) “Implantation” In: Encyclopedia of Animal Science, Marcel Dekker, Inc., Print Published: 11/10/2004; Online Published: 10/29/2004, pages: 555 - 558 DOI: 10.1081/E-EAS-120019690.
Non-Refereed Publications: 1. Fitz TA, RC Burghardt, MM Marr, TL Walden, CA Winkel (1989) Intercellular communication among
SV40-transformed rat granulosa cells may be an index of differentiation. In: Eicosanoids and Other Bioactive Lipids in Cancer and Radiation Injury. (KV Honn, LJ Marnett, S Nigam, TL Walden, Jr, eds,), Kluwer Publ., Boston. pp. 363-367.
2. Burghardt RC, JM Ehrman, TC Stephens, and MF Hibbs (1990) Measurement of microscopic displacements in graphite/epoxy composite materials using a SEM-generated surface map. Proceedings of the XIIth International Congress for Electron Microscopy. Volume IV, pp. 430-431.
3. Tuttle KL, JW Evans, DW Forrest, RC Burghardt (1991) Immunohistochemical localization of luteinizing hormone receptors in equine ovarian follicles. J. Reprod. Fert. Proceedings of the 5th International Symposium on Equine Reproduction. p. 635-636.
4. Burghardt RC, R Barhoumi Mouneimne, MA Walker, GR Newton (1996) Development of laser cytometric approaches to analyze cellular toxicity mechanisms induced by ionizing radiation. Radiation Studies Conference Proceedings, RADSCON'96, pp82-86.
5. Burghardt RC, R Barhoumi (1997) Analysis of mechanisms of cellular injury on the micrometer scale. Microscopy and Microanalysis, Vol 3, Suppl 2, Proceedings: Microscopy and Microanalysis ‘97, pp 37-38.
Abstracts: Selected Published Abstracts (since 2005 only) in addition to 196 earlier published abstracts:
197. Barhoumi R, A Awooda, SH Safe, RC Burghardt. Reversal of benzo-[a]-pyrene on oxytocin-induced Ca2+ oscillations in human myometrial PHM1-41 cells. 44th Annual Meeting of the Society of Toxicology, New Orleans, LA, March 6-10, 2005
198. Pulido M, K Bayless, R Burghardt, G Davis, AR Parrish. Ischemia-induced cleavage of cadherins in NRK cells: evidence for the role of MT1-MMP. 44th Annual Meeting of the Society of Toxicology, New Orleans, LA, March 6-10, 2005
199. Chintharlapalli S, S Papineni, R Burghardt, S Safe. Identification of Nur77 agonists that induce apoptosis and inhibit cancer survival through nuclear pathways. 44th Annual Meeting of the Society of Toxicology, New Orleans, LA, March 6-10, 2005
200. Joyce MM, RD Geisert, RC Burghardt, GA Johnson. Stat 1 is differentially regulated by conceptus estrogen and proteins in the porcine uterus. 38th Annual Meeting of the Society for the Study of Reproduction, Québec, Canada, July 24-27, 2005
201. White FJ, RC Burghardt, BA Croy, GA Johnson. Osteopontin is expressed by endometrial macrophages and decidual natural killer cells during mouse pregnancy. 38th Annual Meeting of the Society for the Study of Reproduction, Québec, Canada, July 24-27, 2005
202. Johnson GA, FJ White, JW Ross, MM Joyce, RD Geisert, RC Burghardt. Steroid regulation of cell specific osteopontin expression in the pregnant porcine uterus. 38th Annual Meeting of the Society for the Study of Reproduction, Québec, Canada, July 24-27, 2005
203. Burghardt RC, FJ White, SJ Gregg, MM Joyce, TE Spencer, GA Johnson. The induction of osteopontin in ovine endometrial stroma requires conceptus attachment. 38th Annual Meeting of the Society for the Study of Reproduction, Québec, Canada, July 24-27, 2005
204. Banerjee A, RC Burghardt, GA Johnson, FJ White, SK Ramaiah. Temporal expression and localization of osteopontin mRNA and protein in the rat alcoholic steatohepatitis model. American College of Toxicology annual meeting, Williamsburg, VA, November 6-9, 2005
205. Johnson GA, RC Burghardt. Secreted Phosphoprotein-1 (Osteopontin) Contributes to Conceptus Attachment and Decidual Angiogenesis in Mice. Gordon Research Conference on Small Integrin-Binding Proteins, Big Sky, MT, September 11-16, 2005
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206. Barhoumi R, I Awooda, RC Burghardt. Changes in Ca2+ Oscillations in Human Myometrial Cells Associated with Toxicant Exposure. 45th Annual Meeting, Society of Toxicology, San Diego, CA, March 5-9, 2006
207. Liu S, S Khan, R Barhoumi, R Burghardt, K Kim, S Safe. Mechanisms of Inhibitory Aryl Hydrocarbon Receptor-Estrogen Receptor α/SP1 Crosstalk in Breast Cancer Cells. 45th Annual Meeting, Society of Toxicology, San Diego, CA, March 5-9, 2006
208. Abdelrahim M, E Ariazi, K Kim, S Khan, R Barhoumi, R Burghardt, S Liu, B Wlodarczyk, D Hill, R Finnell, V Jordan, S Safe. 3-methylcholanthrene and Other Aryl Hydrocarbon Receptor Agonists Directly Activate Estrogen Receptor Alpha . 45th Annual Meeting, Society of Toxicology, San Diego, CA, March 5-9, 2006
209. Hayashi K, RC Burghardt, MC Satterfield, FW Bazer TE Spencer. Wnt Signaling in the Ovine Uterus: Potential Regulation of Conceptus Growth and Differentiation 39th Annual Meeting of the Society for the Study of Reproduction, Omaha, NB, July 29-Aug 1, 2006
210. Farmer JL, KA Dunlap, K Hayashi, TE Spencer, RC Burghardt. Establishment and Initial Characterization of an Ovine Trophectoderm Cell Line. 39th Annual Meeting of the Society for the Study of Reproduction, Omaha, NB, July 29-Aug 1, 2006
211. Joyce MM, JR Burghardt, RC Burghardt, RN Hooper, LA Jaeger, GA Johnson. Pig Conceptus Interferon (IFN) Gamma May Ablate Uterine Major Histocompatibility Complex (MHC) Class I and Beta-2 Microglobulin (B2) Expression at the Maternal-placental Interface. 39th Annual Meeting of the Society for the Study of Reproduction, Omaha, NB, July 29-Aug 1, 2006
212. Burghardt RC, FJ White, J Hu, MM Joyce, TE Spencer, GA Johnson. Secreted Phosphoprotein 1 (Spp1, Osteopontin) is Induced by Estrogen in Mouse Uterine Lumenal Epithelium During Conceptus Attachment for Implantation. 39th Annual Meeting of the Society for the Study of Reproduction, Omaha, NB, July 29-Aug 1, 2006
213. Al-Ramadan, H Ka, GA Johnson, LA Jaeger, RC Burghardt, TE Spencer, FW Bazer. Regulation of Fibroblast Growth Factor 7 (FGF7) in the Pig Uterine Endometrium by Progesterone (P4) and Estradiol (E2). 39th Annual Meeting of the Society for the Study of Reproduction, Omaha, NB, July 29-Aug 1, 2006
214. Johnson GA, JR Burghardt, JD Taylor, II, AT Reeder, BT Nguyen, RC Burghardt. Evidence for Integrin Activation (Focal Adhesion Formation) in at the Conceptus-maternal Interface of Pregnant Sheep. 39th Annual Meeting of the Society for the Study of Reproduction, Omaha, NB, July 29-Aug 1, 2006
215. Spencer TE, FW Bazer, GA Johnson, M Palmarini, RC Burghardt. Fetal-maternal interactions during the establishment of pregnancy. 7th International Ruminant Reproduction Symposium, Wellington, New Zealand, Aug 13-17, 2006.
216. Burghardt RC, AT Reeder, BT Nguyen, JR Burghardt, JD Taylor II, TE Spence, GA Johnson Focal adhesions assemble between ovine myometrial cells during pregnancy in response to mechanosensation/mechanotransduction and are dismantled after parturition. 40th Annual meeting of the Society for the Study of Reproduction, San Antonio, TX, July 21-25, 2007
217. Johnson GA, Dunlap KA, Erikson DW, Reed KM, White FJ, Burghardt RC and Bayless KJ. The sheep conceptus differentially regulates uterine secreted phosphoprotein 1 for increased histotrophic and hematotrophic support of pregnancy. 40th Annual meeting of the Society for the Study of Reproduction, San Antonio, TX, July 21-25, 2007
218. Erikson DW, Burghardt RC, Jaeger LA, Bayless KJ, Johnson GA Secreted Phosphoprotein 1 isolated from uterine secretions promotes integrin-mediated adhesion of porcine trophectoderm cells. 40th Annual meeting of the Society for the Study of Reproduction, San Antonio, TX, July 21-25, 2007
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219. Dunlap KA, EA Mendoza, RC Burghardt, TE Spencer, FW Bazer, KJ Bayless, GA Johnson. Involvement of sphingosine-1-phosphate (S1P) and secreted phosphoprotein 1 (SPP1, or osteopontin) in regulating uterine angiogenesis for pregnancy. 40th Annual meeting of the Society for the Study of Reproduction, San Antonio, TX, July 21-25, 2007
220. Farmer JL, RC Burghardt, D Jousan, PJ Hansen, FW Bazer, TE Spencer. Biological functions of Galectin 15 (LGALS15) in the ovine uterus. 40th Annual meeting of the Society for the Study of Reproduction, San Antonio, TX, July 21-25, 2007
221. Lewis SK, JL Farmer, RC Burghardt, GR Newton, DL Adelson, FW Bazer, TE Spencer.Galectin-15 (LGALS15): A gene confined to sheep and goats? 40th Annual meeting of the Society for the Study of Reproduction, San Antonio, TX, July 21-25, 2007
222. Massuto D, RN Hooper, E Kneese, GA Johnson, RC Burghardt, LA Jaeger. Intrauterine infusion of recombinant transforming growth factor beta latency associated peptide disrupts porcine conceptus development. 40th Annual meeting of the Society for the Study of Reproduction, San Antonio, TX, July 21-25, 2007
223. Spencer TE, RC Burghardt, GA Johnson, G Wu, FW Bazer. Pathways regulating conceptus-endometrial interactions: Insights from the sheep. Second International Meeting on Mammalian Embryogenomics, Oct 17-20, 2007, Paris, France
224. Dunlap KA, H-I Kwak, S-C Su, EA Mendoza, RC Burghardt, FW Bazer, RR Magness, GA Johnson, KJ Bayless. Involvement of the sphingosine-1-phosphate cell signaling pathway in regulating ovine endometrial angiogenesis during pregnancy. Society for the Study of Reproduction, 41st Annual Meeting May 27-30, 2008, Kailua-Kona, HI
225. Bailey D, KA Dunlap, G Song, Ha Gao, DW Erikson, FW Bazer, G Wu, RC Burghardt, GA Johnson. Prolonged progesterone exposure in the absence of conceptus factors has predicted effects on uterine physiology, but does not support uterine gland development or Spp1 and FGF7 expression in pigs. Society for the Study of Reproduction, 41st Annual Meeting, May 27-30, 2008, Kailua-Kona, HI
226. Erikson DW, RC Burghardt, LA Jaeger, KJ Bayless, GA Johnson. Secreted Phosphoprotein 1 (SPP1, Osteopontin) mediates porcine conceptus adhesion through specific integrin receptors on conceptus trophectoderm and uterine luminal epithelium. Society for the Study of Reproduction, 41st Annual Meeting, May 27-30, 2008, Kailua-Kona, HI
227. DA Massuto, EC Kneese, RN Hooper, NH Ing, GA Johnson, RC Burghardt, LA Jaeger Differential expression of integrins and latency associated peptide (LAP) implicate functional roles in conceptus-maternal communication during porcine periimplantation. Society for the Study of Reproduction, 41st Annual Meeting, May 27-30, 2008, Kailua-Kona, HI
228. J Kim, TE Spencer, G Song, RC Burghardt, G Wu, GA Johnson, FW Bazer. Arginine, leucine, glutamine, and glucose stimulate on PI3K-AKT1 and FRAP1-RPS6K signaling cascades in ovine conceptuses. Society for the Study of Reproduction, 41st Annual Meeting, May 27-30, 2008, Kailua-Kona, HI
229. GA Johnson, J Kim, DW Erikson, G Song, TE Spencer, KJ Bayless, G Wu, RC Burghardt, FW Bazer Secreted Phosphoprotein One (SPP1 or Osteopontin) binds αvβ3 and α5β1 integrins on ovine trophectoderm to mediate cell attachment and stimulate the FRAP1/mTOR Pathway. Society for the Study of Reproduction, 41st Annual Meeting, May 27-30, 2008, Kailua-Kona, HI
230. RC Burghardt, TE Spencer, KJ Bayless, JR Burghardt, GA Johnson. Enhanced focal adhesion assembly reflects increased mechanosensation and mechanotransduction along the uterine wall during pregnancy in sheep. Society for the Study of Reproduction, 41st Annual Meeting, May 27-30, 2008, Kailua-Kona, HI
231. S Black, RC Burghardt, MC Satterfield, C Long, C Hanna, M Palmarini, TE. Spencer. Evidence for in vivo transduction of endogenous Jaagsiekte sheep retrovirus in the uterus. International Federation of Placenta Associations Meeting, Sept 10-13, 2008, Seggau Castle, Austria
232. DD Dean, A Steelman, A Arenas-Gambon, A Rice-Ficht, C Young, F Bazer, R Burghardt, CJ Welsh. Immunomodulation of Theiler’s virus-induced demyelination [TVID] using encapsulated ovine interferon-tau [IFNT]: The novel administration of a novel type I IFN in an animal model of multiple
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sclerosis (MS]. 9th International Congress of Neuroimmunology, October 26-30, 2008, Fort Worth, TX 233. TE Spencer, GA Johnson, RC. Burghardt, G Wu, FW Bazer. Conceptus-endometrial interactions in
ruminants. 6th International Congress on Farm Animal Endocrinology, November 14-16, 2008, Roanoke, VA
234. AR Parrish, RC Burghardt. N-cadherin expression dictates acute injury in response to mercuric chloride and simulated ischemia. Society of Toxicology, 48th Annual Meeting, March 15-19, 2009, Baltimore, MD
235. GA Johnson, G Song, DW Bailey, KA Dunlap, RC Burghardt, TE Spencer FW Bazer. Cathepsin B, cathepsin l and cystatin c in the porcine uterus and placenta: a model for fluid-phase transport of proteins across uterine epithelia, areolae and neonatal gut. Biol Reprod, July 2009; 81: 403. Society for the Study of Reproduction, 42nd Annual Meeting, Pittsburgh, PA, July 18-23, 2009
236. KA Dunlap, X Li, MC Satterfield, RC Burghardt, DW Erikson, ML Halverson, G Wu, TE Spencer, RR Magness, KJ Bayless, and GA Johnson. Antagonism of the sphingosine-1-phosphate (S1P) signaling pathway in pregnant ewes alters placentome architecture, amino acid transport and fetal growth. Biol Reprod, July 2009; 81: 427. Society for the Study of Reproduction, 42nd Annual Meeting, Pittsburgh, PA, July 18-23, 2009
237. H Gao, GA. Johnson, G Wu, DW Bailey, RC. Burghardt, FW Bazer. Glucose and glucose transporters in pig uteri and conceptuses. Biol Reprod, July 2009; 81: 402. Society for the Study of Reproduction, 42nd Annual Meeting, Pittsburgh, PA, July 18-23, 2009
238. J Kim, TE Spencer, RC Burghardt, G Wu, GA Johnson, FW Bazer. Arginine stimulates proliferation of ovine trophectoderm cells through FRAP1-RPS6K-RPS6 signaling cascade and synthesis of nitric oxide and polyamines. Biol Reprod, July 2009; 81: 488. Society for the Study of Reproduction, 42nd Annual Meeting, Pittsburgh, PA, July 18-23, 2009
239. S Black, RC Burghardt, MC Satterfield, C Long, C Hanna, K Tessane, M Palmarini, TE Spencer. Evidence for transmission of endogenous betaretroviruses from the maternal uterus to the conceptus in sheep. Biol Reprod, July 2009; 81: 180. Society for the Study of Reproduction, 42nd Annual Meeting, Pittsburgh, PA, July 18-23, 2009
240. DW Erikson, RC Burghardt, FW Bazer, GA Johnson, KJ Bayless. Secreted phosphoprotein 1 (SPP1, osteopontin) stimulates adhesion and migration of circulating endothelial cells in pigs. Society for the Study of Reproduction, 42nd Annual Meeting, Pittsburgh, PA, July 18-23, 2009
241. RM Simmons, DW Erikson, J Kim, RC Burghardt, GA Johnson, FW Bazer, TE Spencer. IGFBP1, HSD11B1, and prostaglandins in the ovine uterus during early pregnancy. Biol Reprod, July 2009; 81: 181. Society for the Study of Reproduction, 42nd Annual Meeting, Pittsburgh, PA, July 18-23, 2009
242. Indira D. Jutooru, G. Chadalapaka, S. Sreevalsan, P. Lei, R. Barhoumi, R. Burghardt, S.H. Safe. Arsenic trioxide downregulation of specificity protein (SP) transcription factors in bladder cancer cells is dependent on reactive oxygen species (ROS). Society of Toxicology, 49th Annual Meeting, March 7-11, 2010, Salt Lake City, UT
243. Lesley A. Gardiner, RC Burghardt, AR Parrish. Comparative nephrotoxicity of low-osmolar and iso-osmolar iodinated contrast agents. Society of Toxicology, 49th Annual Meeting, March 7-11, 2010, Salt Lake City, UT
244. X Li, FW Bazer, RC Burghardt, GA Johnson, I Shinzato, TE Spencer, G Wu. Impacts of dietary supplementation with L-arginine between days 0 and 25 of gestation on the reproductive performance of gilts. Experimental Biology Meeting, 2010, April 24-28, 2010, Anaheim, CA
245. G Wu, FW Bazer, RC Burghardt, GA Johnson, DA Knabe, X Li, TE Spencer, JJ Wang. Important roles for L-glutamine in swine nutrition, growth and production. American Society of Animal Science, 2010, July 11-15, 2010
246. J Kim, RC Burghardt, G Wu, GA Johnson, TE Spencer, FW Bazer. Arginine stimulates migration of ovine trophectoderm cells through mTOR-RPS6-RPS6K signaling cascade and synthesis of nitric oxide, polyamines and interferon tau. Society for the Study of Reproduction, 43rd Annual Meeting, July 30-Aug.3, 2010, Milwaukee, WI.
247. GA. Johnson, H Gao, X Li, ML Halvorsen, G Wu, RC Burghardt, FW Bazer. Glucose, amino acids and their transporters in pig uteri, conceptuses and placentae. Society for the Study of Reproduction, 43rd
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Annual Meeting, July 30-Aug.3, 2010, Milwaukee, WI. 248. KJ Bayless, DW Erikson, JW Frank, MM Joyce, RC Burghardt, FW Bazer, GA Johnson. Recruitment
and modulation of porcine endothelial progenitor cells by secreted phosphoprotein 1 (SPP1, Osteopontin). Society for the Study of Reproduction, 43rd Annual Meeting, July 30-Aug.3, 2010, Milwaukee, WI.
249. DW Erikson, Y-H Hsieh, K Hayashi, RC Burghardt, KJ Bayless, P-L Chang, GA Johnson. SPP1 (Osteopontin) and SPARC (Osteonectin) may interact developmentally during mouse pregnancy. Society for the Study of Reproduction, 43rd Annual Meeting, July 30-Aug.3, 2010, Milwaukee, WI.
250. SK. Banu, JA Stanley, J Lee, TK Nithy, JA Arosh, PB Hoyer, MM Aruldhas, RC Burghardt. Gestational exposure to chromium (VI) impairs pregnancy outcome and fetal development. Society for the Study of Reproduction, 43rd Annual Meeting, July 30-Aug.3, 2010, Milwaukee, WI.
251. J Kim, RC Burghardt, G Wu, GA Johnson, TE Spencer, FW Bazer. Differential effects of arginine, leucine, glutamine and glucose on expression of interferon tau, orinithine decarboxylase and nitric oxide synthase by explant cultures of ovine conceptuses. 8th International Ruminant Reproduction Symposium, Sept 3-7, 2010 Anchorage, AL.
252. JA Arosh JA, J Lee, RC Burghardt, SK Banu. Selective inhibition of prostaglandin E2 receptors EP2 and EP4 inhibits adhesion, migration, and invasion of human endometriotic epithelial and stromal cells through suppression of integrins and metalloproteinases-mediated mechanisms. American Society for Reproductive Medicine, 66th Annual Meeting, October 23-27, Denver, CO.
253. Frank JW, X Li, DW Erikson, BG White, G Wu, F. Bazer, RC Burghardt, KJ. Bayless, GA Johnson. Integrin Av (ITGAV) is necessary for the attachment of trophoblast cells to SPP1 (osteopontin) to mediate adhesion of the conceptus to the uterus during implantation in pigs. Society for the Study of Reproduction, 44rd Annual Meeting, July 31-August 4, 2011, Portland, OR. * Selected as a Finalist for the Trainee Research Award Competition.
254. Li X, FW Bazer, GS Johnson, RC Burghardt, DW Erikson, JW Frank, J Wang, Guoyao Wu. Impacts of dietary supplementation with L-arginine between days 14 and 25 of gestation on the reproductive performance of gilts. Society for the Study of Reproduction, 44rd Annual Meeting, July 31-August 4, 2011, Portland, OR.
255. Banu SK, JA Stanley, JH Lee, SD Stephen, JA. Arosh, PB Hoyer, RC Burghardt. Lactational exposure to hexavalent chromium Induced follicular atresia in pre-pubertal F1 offspring: molecular signaling integration of granulosa cell apoptosis. Society for the Study of Reproduction, 44rd Annual Meeting, July 31-August 4, 2011, Portland, OR.
256. Stanley JA, JH Lee, JA Arosh, PB Hoyer, RC Burghardt, SK Banu. Hexavalent chromium through lactational exposure delayed follicular development in pre-pubertal F1 offspring: mechanistic insights into cell cycle regulation of granulosa cells. Society for the Study of Reproduction, 44rd Annual Meeting, July 31-August 4, 2011, Portland, OR.
257. Andrews T, GA Johnson, G Wu, R Burghardt, T Spencer, FW Bazer. Effects of mTORC2 on ovine conceptus elongation and implantation. Society for the Study of Reproduction, 44rd Annual Meeting, July 31-August 4, 2011, Portland, OR.
258. Chang G, B White, EM Black, J. Frank, R Burghardt, G Johnson. Expression of alpha-2-beta-1 and claudin-4 protein at the uterine-placental interface suggests roles in the transport of proteins and nutrients from the mother to fetus in pigs. Society for the Study of Reproduction, 44rd Annual Meeting, July 31-August 4, 2011, Portland, OR.
259. White BG, KA Dunlap, JW. Frank, MC Satterfield, RC Burghardt, FW Bazer, GA Johnson, KJ Bayless. Manipulation of the Sphingosine-1-Phospate signaling pathway decreases placental and fetal development. International Federation of Placenta Association Meeting, Sept 14-17, 2011, Geilo, Norway.
260. Ying W, X Wang, K Dunlap, J Short, MC Satterfield, R Burghardt, G Johnson, I Ruiz-Gonzalez, AQ Antoniazzi, TM Nett, TR Hansen, FW Bazer. Regulation of expression and consequences of silencing translation of toll-like receptors 7 and 8 messenger RNAs in the ovine uterus. Society for the Study of Reproduction, 45th Annual Meeting, August 12-15, 2012, State College, PA.
261. Johnson GA, JW Frank, RC Burghardt, FW Bazer, G Wu. A role for osteopontin and integrins in nutrient
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transport by placentae. Society for the Study of Reproduction, 45th Annual Meeting, August 12-15, 2012, State College, PA.
262. White BG, JW Frank, MC Satterfield, FW Bazer, GA Johnson, KJ Bayless. Antagonism of the S1P pathway affects placental and fetal development. Society for the Study of Reproduction, 45th Annual Meeting, August 12-15, 2012, State College, PA.
263. Wang X, K Dunlap, MC Satterfield, X Li, W Ying, R Burghardt, GA Johnson, G Wu, AQ Antoniazzi, TM Nett, TR Hansen, FW Bazer. Effects of in vivo knockdown of translation of arginine-associated gene transcripts in conceptus trophectoderm on growth, development, and gene expression by ovine conceptuses. Society for the Study of Reproduction, 45th Annual Meeting, August 12-15, 2012, State College, PA.
264. Nithy T, J Lee, SK Banu, RC Burghardt, JA Arosh. Inhibition of prostaglandin E2 receptors EP2 and EP4 inhibits adhesion of human endometriotic epithelial and stromal cells through deregulated integrin-mediated mechanisms. Society for the Study of Reproduction, 45th Annual Meeting, August 12-15, 2012, State College, PA.
265. Frank JW, MM Joyce, RC Burghardt, GA Johnson. Temporal and spatial expression of interferon-stimulated gene 15 and Mx1 during pregnancy in the pig. Society for the Study of Reproduction, 45th Annual Meeting, August 12-15, 2012, State College, PA.
266. Wing T, H Gao, X Li, RC Burghardt, G Wu, FW Bazer, GA Johnson. Expression and regulation of genes for glucose and arginine transporters in pig uteri, conceptuses, and placentae. Society for the Study of Reproduction, 45th Annual Meeting, August 12-15, 2012, State College, PA.
267. Wing T, DE Erikson, FW Bazer, RC Burghardt, GA Johnson, KJ Bayless. Osteopontin binds to the αv integrin promoting porcine endothelial progenitor cell (EPC) incorporation into developing vasculature. Society for the Study of Reproduction, 46th Annual Meeting, July 22-26, 2013, Montreal, Quebec.
268. Wang X, K Dunlap, M Satterfield, R Burghardt, GA Johnson, G Wu, FW Bazer. Arginine and secreted phosphoprotein 1 act synergistically to stimulate MTORC1/MTORC2 cell signaling and cytoskeletal organization for proliferation, adhesion and migration of ovine trophectoderm cells. Society for the Study of Reproduction, 46th Annual Meeting, July 22-26, 2013, Montreal, Quebec.
269. Ying W, X Wang, K Dunlap, G Wu, M Satterfield, M Uzelac, A Keith, R Burghardt, G Johnson, F Bazer. Arginine decarboxylase/agmatinase: An alternative pathway for synthesis of polyamines in the ovine conceptus and uterus. Society for the Study of Reproduction, 46th Annual Meeting, July 22-26, 2013, Montreal, Quebec.
270. Burroughs C, J Vallet, G Wu, R Burghardt, F Bazer, G Johnson. Possible role of transporters: Possible roles of transporters SLC2A5 and SLC2A8 in fructose movement between maternal and fetal tissues during pig pregnancy. Society for the Study of Reproduction, 46th Annual Meeting, July 22-26, 2013, Montreal, Quebec.
271. Frank JW, RC Burghardt, C Satterfield, FW Bazer, GA Johnson. Loss of integrin subunit β3 during the peri-implantation period leads to fetal growth retardation in the sheep. Society for the Study of Reproduction, 46th Annual Meeting, July 22-26, 2013, Montreal, Quebec.
272. Banu SK, JA Stanley, JA Arosh, KK Sivakumar, RC Burghardt. Synergistic effects of resveratrol and curcumin on chromium-induced reproductive toxicity in female rats. Society for the Study of Reproduction, 46th Annual Meeting, July 22-26, 2013, Montreal, Quebec.
273. Rezaei R, S Dahanayaka, WW Porter, RC Burghardt, GA Johnson, Y Tian, FW Bazer, G Wu Preparation and culture of porcine mammary epithelial cells. 13th International Congress on Amino Acids, Peptides and Proteins (ICAPP), Oct. 5-7, 2013 Galveston, TX
274. Burroughs CA, M Landers, H Gao, JL Vallet, G Wu, RC Burghardt, FW Bazer, GA Johnson. Cell localization of SLC2 glucose transporter family member mRNA in endometria and placentae from pregnant pigs. Society for the Study of Reproduction, 47th Annual Meeting, July 19-23, Grand Rapids, MI.
275. Wang X, W Ying, KA Dunlap, G Lin, MC Satterfield, RC Burghardt, G Wu, FW Bazer. Arginine decarboxylase and agmatinase: an alternative pathway for de novo biosynthesis of polyamines for development of mammalian conceptuses. Society for the Study of Reproduction, 47th Annual Meeting,
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July 19-23, Grand Rapids, MI. 276. Steinhauser CB, Landers M, Myatt L, Burghardt RC, Wu G, Vallet J, Bazer FW, Johnson GA.
Localization of the polyol pathway enzymes to the porcine uterine luminal epithelium and placental chorion provides a pathway for conversion of glucose to fructose. Society for the Study of Reproduction, 48th Annual Meeting, July 18-22, 2015, San Juan, Puerto Rico.
277. Seo H, Li X, Bazer FW, Burghardt RC, Wu G, Bayless KJ, Johnson GA. Mechanotransduction drives morphogenesis to develop folding at the uterine-placental interface of pigs. Society for the Study of Reproduction, 48th Annual Meeting, July 18-22, 2015, San Juan, Puerto Rico.
278. Gao Y, Kang B, Davis AJ, Burghardt R, Bayless KJ, Li Q. Dysregulation of TGF-beta signaling alters uterine fibroblast cell function. Society for the Study of Reproduction, 48th Annual Meeting, July 18-22, 2015, San Juan, Puerto Rico.
279. Seo H, Bazer FW, Burghardt RC, Johnson GA. Syncytial trophoblast fusion and breaching of uterine luminal epithelium during implantation in sheep. Society for the Study of Reproduction, 49th Annual Meeting, July 16-20, 2016, San Diego, CA.
280. Satterfield MC, Brown JD, Miller AL, Levy M, Burghardt RC, Johnson GA, Bazer FW, Wu G, Zhang R. Growth and development of rat pups with gestational exposure to sulfur based particulate matter. Society for the Study of Reproduction, 49th Annual Meeting, July 16-20, 2016, San Diego, CA.
281. Zhu C, Li X, Bazer FW, Johnson GA, Burghardt RC, Jiang Z, Wu G. Dietary L-arginine supplementation between days 14 and 25 of gestation enhances placental aquaporin-1 protein expression and water transport by the pig placenta. Society for the Study of Reproduction, 49th Annual Meeting, July 16-20, 2016, San Diego, CA.
282. Johnson GA, Frank JWA, Steinhauser CB, Wang X, Seo H, Wu G, Burghardt R, Bazer FW. Functional loss of ITGB3 (beta 3 integrin) in ovine conceptuses slows conceptus development and decreases conceptus expression of nitric oxide synthase 3 and secreted phosphoprotein 1 (OPN). Society for the Study of Reproduction, 49th Annual Meeting, July 16-20, 2016, San Diego, CA.
PATENTS AND RELATED DISCOVERY ACTIVITIES Patents:
U.S. Patent #6521402, Cryopreservation of Tissues for Use in Nuclear Transfer, Issue date 2/18/2003, RC
Burghardt, ME Westhusin, D Dean. Discovery Activities: Invention disclosure #3549 TAMUS Office of Technology Commercialization, 2011, Spontaneously Immortalized
Granulosa Cell Line Derived from the Rat Ovary. G Stoica and RC Burghardt. Invention disclosure #1158 TAMU System Technology Licensing Office, 1997, Micro Electroporation Electrodes
Y. Mouneimne, R. Barhoumi Mouneimne, R.C. Burghardt. Invention disclosure #1220 TAMU System Technology Licensing Office, 1997, Signal Analysis Microscopy. R.
Barhoumi Mouneimne, Y. Mouneimne, R.C. Burghardt. Invention disclosure TAMU System Technology Licensing Office, 1997, Disposable Cell Culture Electroporation
Chamber and Chamber Holder Y. Mouneimne, R. Barhoumi Mouneimne, R.C. Burghardt. Invention disclosure: Universal binding system for diagnosis and therapy. Y Mouneimne, R Mouneimne, RC
Burghardt, Submitted June 13, 2000. Invention disclosure: #3237 TAMU System Office of Technology Commercialization, 2010, Multiphoton
microscopy spectral analysis for identification and quantification of fluorescent environmental toxicants and their genotoxic and nongenotixic metabolites in living cells. R. Barhoumi Mouneimne and R.C Burghardt, September 24, 2010.
Invention disclosure #3459. TAMU System Office of Technology Commercialization, Spontaneously immortalized granulosa cell line derived from rat. G. Stoica and RC. Burghardt, June 29, 2011.
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SERVICE ACTIVITIES: Professional Organizations and Service: Professional Organizations:
American Society for Cell Biology, Member, 1979-1998 American Association for Cancer Research, Member, 1992-1998 American Association for the Advancement of Science, Member, 1991- Society for the Study of Reproduction, Member, 1984- Society of Toxicology, Member, 1999- Professional Service: Editorial Board Member, Cells Tissues Organs, 2004-present Editorial Board Member, Journal of Applied Toxicology, 2006-present Service to the Society for the Study of Reproduction (SSR): Associate Editor, Biology of Reproduction, 1992-1995. Referring Editor, Biology of Reproduction. Responsible for editorial oversight for appeals to Editor-in-Chief
for contested decisions, 2001-2004. Member, Local Arrangements Committee, 1998 SSR, 31st Annual Meeting, College Station, TX. Chair, Publications Committee, SSR, 1996-2000. Co-Chair 2005-2008. Responsible for developing proposal
and selecting HighWire Press for production of Biology of Reproduction on the World Wide Web beginning July, 1998. Responsible for selection of Editor-in-Chief and Associate Editors for the term, 1999-2004 and for selection of Editors-in-Chief for the term beginning July, 2009 through 2013.
Director (Elected), Board of Directors, SSR, 2000-2003 Secretary (Elected), Member, Finance Committee, Executive Committee and Board of Directors, SSR, 2010-
2013 Member, Awards Committee, SSR, 2003-2004. Chair, Awards Committee, SSR, 2004-2005. Responsible for oversight of selection of individuals for major
awards of the society including the Carl G. Hartman Award, The SSR Research Award, The SSR Distinguished Service Award, The New Investigator Award, Trainee Research Competition Awards (3 platform and 3 poster), and Trainee Travel Awards (about 40). Also developed with counterpart from the American Association for Reproductive Medicine (ASRM), a Speaker Exchange program recognizing the SSR Research Award and corresponding research award winner from ASRM at each other’s annual meeting.
Chair, Ad hoc Committee appointed by SSR President to develop recommendations for upgrading SSR
website, 2005-2006. Member, SSR Strategic Planning Committee, 2003-2004. Chair, Strategic Planning Subcommittee for the Society’s journal, Biology of Reproduction, 2003-2004. Chair, SSR Strategic Planning Committee, SSR, 2008-2009. Member, Strategic Planning Implementation Committee, SSR, 2010-2014
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Service to Other Organizations Coordinator, Texas Women’s Reproductive Health Consortium, 2000-2004. Member, Steering Committee, Texas Forum for Reproductive Sciences, 2000-2008; 2010-present Member, Gulf Coast Society of Toxicology, 1997 Program Committee. External reviewer, Academic Program Review, Physiological Sciences Graduate Interdisciplinary Program,
University of Arizona, Tucson, Arizona, April 13-14, 2010. Guest Editor, Domestic Animal Endocrinology, Responsible for oversight of peer review of manuscripts
submitted by members of Domestic Animal Endocrinology Editorial Office, 2001. External reviewer, Graduate Program Review, Veterinary Biomedical Sciences Program, University of
Saskatchewan, Saskatoon, Saskatchewan, March 3-4, 2016.
Manuscript Review for Journals: Ad hoc reviewer (55 journals):
Acta Anatomica; American Journal of Obstetrics and Gynecology; American Journal of Physiology: Cell Physiology; American Journal of Physiology: Heart and Circulatory Physiology; American Journal of Physiology: Endocrinology and Metabolism; American Journal of Physiology: Regulatory, Integrative and Comparative Physiology; American Journal of Veterinary Research; Animal Reproduction Science; Birth Defects Research Part A: Clinical and Molecular Teratolog; Biochemical Pharmacology; Biology of Reproduction; Bioorganic & Medicinal Chemistry Letters; BioTechnique; Cancer Chemotherapy and Pharmacology; Cancer Letters; Cancer Prevention Research; Cell and Tissue Research; Cells Tissues Organs; Cereal Chemistry; Comparative Biochemistry and Physiology; Differentiation; Domestic Animal Endocrinology; Endocrinology; European Journal of Obstetrics & Gynecology and Reproductive Biology; Experimental Cell Research; Food Additives and Contaminants; Human Reproduction; In Vitro Cellular and Developmental Biology; Journal of the American Aging Association; Journal of Animal Science; Journal of Animal Science and Biotechnology; Journal of Applied Toxicology; Journal of Cardiovascular Pharmacology; Journal of Endocrinology; Journal of Pharmacology and Experimental Therapeutics; Journal of Reproduction and Fertility; Life Sciences; Manual of Environmental Microbiology; Molecular and Cellular Biochemistry; Molecular Carcinogenesis; Molecular Human Reproduction; Molecular Reproduction and Development; Neurotoxicology; Placenta; PLOS ONE; Reproduction; Reproductive Biology and Endocrinology; Science of the Total Environment; Society for Experimental Biology and Medicine; Theriogenology; Trends in Endocrinology & Metabolism; Toxicology & Environmental Chemistry; Toxicology Letters; Toxicological Sciences (54)
Ad hoc reviewer for professional publishers: Elsevier Science Ltd. American Society for Microbiology Press Books
Major Committee Assignments: Departmental:
Member, Search Committee, Developmental Biologist, 1990. Member, Search Committee, Cell Biology/Histology Position, 1993 Member, Search Committee, Microscopic Anatomy, Fall 1993 Chair, Promotion and Tenure Committee, 1993-2005
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Member, Promotion and Tenure Committee, 2005-present Member, Department of Veterinary Anatomy & Public Health Executive Committee, 2000-present Member, Search Committee, Microscopic Anatomy, 2000-2001 Chair, Search Committee, Gross Anatomy, Reproductive Biology, 2003 Member, Search Committee, Reproductive Biology, 2009-2010 Member, VIBS Strategic Planning Committee 2009-2010
College: Director, Image Analysis Laboratory, 1987-present, College of Veterinary Medicine. Coordinated the
development of a centralized analytical microscopy research laboratory for the College via consolidation of departmental resources and acquisition of new technologies. Responsible for purchase and subsequent upgrade of an ACAS 570 Interactive Laser Cytometer (upgraded to a Meridian Ultima Confocal System), a JEOL JSM 25-SII scanning electron microscope, a Balzers Freeze Fracture Device, a Zeiss PM III photomicroscope, a Scanalytics fluorescence deconvolution workstation, PTI ratiometric fluorescence workstation, a Meridian InSIGHT Point video rate scanning laser confocal microscope, an image analysis workstation (Axiophot, 3 chip color camera, power Mac, digital printer, scanner), a Hacker Cryostat, a Bio-Tek Fluorescence/Absorbance Reader, Eppendorf micromanipulator/ microinjection system, Quantix, Orca DMX-1200, and Axiocam digital cameras, Bio-Rad MP 2000 Multiphoton microscope, Applied Spectral Imaging system, Stallion Dual Detection System, Olympus live cell imaging workstation, Zeiss 510 Meta NLO multiphoton confocal microscope, Veritas Laser Capture Dissection system, FEI Company Morgani TEM, Zeiss TIRF3 microscope, Zeiss Elyra S.1 super resolution microscope, Zeiss 780 NLO multispectral microscope and others. Responsible for acquisition of support equipment including computers, film recorder, microtomes, cell culture facilities, photographic and gold sputtering equipment. Developed renovation plan and managed $300K laboratory renovation, 1998-1999. Developed laboratory policies and procedures and equipment instructional materials.
Media Resources Committee, 1988-1991. College of Veterinary Medicine. Member, Building and Remodeling Committee, 1994-1995 Member, Imaging Symposium Committee, 1989. Member, CVM Promotion and Tenure Committee, 1993-2005 Chair, CVM Promotion and Tenure Committee, 1997-1998 Member, Department Head Search Advisory Committee, 1998-1999 Member, CVM - Graduate Student Association, Travel Awards Committee, 1998-2000 Member, Search Committee, Chair in Stallion Reproduction, 2000-2001 Member, Signature Program Searches in Reproductive Biology, 2004-2005 Member, Cell Biologist Search Committee, Veterinary Pathobiology, 2007-2008 Member, Toxicologist Search Committee, Veterinary Physiology & Pharmacology, 2008-2009. Advisor, CVM Postdoctoral Association, 2009-present Member, Graduate Recruitment Task Force, 2010-2011 Member, CVM Strategic Planning Committee, 2010-2012
University: Graduate Council Representative on Ph.D. examining committees, 1978-2003. Member, Institutional Self-Study preparing for Southern Association of Colleges and Schools review.
Section IX. Special Activities 1982-1983. Member, Selection Committee, Faculty Distinguished Achievement Awards, 1987. Member (ex officio), Electron Microscopy Advisory Committee, 1982-1987. Member, Electron Microscopy Users Committee, 1987-1988. Director, Texas A&M University Electron Microscopy Center, 1982-1987. Supervision of research
operations for the campus electron microscope, electron microprobe research facility; coordinate teaching activities (3 graduate and 2 undergraduate courses); coordinate equipment proposals;
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responsible for acquisition of 3 electron microscopes (Philips 400T-NSF equipment grant, Zeiss 10C and JEOL JSM 35 through proposals for President's research incentive funds); obtained funding for Zeiss Photomicroscope III, an EDAX Energy-dispersive x-ray microanalyzer and a Zeiss SEM-IPS image memory/image processor-image analysis unit; verify equipment competence of new equipment users; provide consulting to University life- and physical sciences personnel.
Member, Search Committee for molecular biology/genetics/biochemistry position, Department of Animal Science, 1991-1992.
Member, Planning Committee, 1994 TAES Science Conference, 1993. Member, National Science Board and Government University Industry Research Round table study,
Individual Scholar Task Force Committee, 1994. Member, Center for Food Safety Program and Scheduling Committee, 1995. Chair, Research Assistantship Selection Committee, Faculty of Reproductive Biology, 1995-present Member, Imaging and Visualization Resources Committee, 1996-1997 Member, Executive Committee, Center for Environmental and Rural Health, 1999-present Member, Search Committee, E.M. Center Director, 1998-2000 Member, Search Committee, Physiological Genomics position, Department of Animal Science, 2001 Member, Search Committee, Reproductive Biology Signature Program Searches, 2004-2005 (two positions
filled in 2004). Member, Search Committee, Molecular Endocrinology position, Department of Animal Science, 2005 Member, Interdisciplinary Life Sciences Building Committee, 2005 Member, Research Roadmap Committee, 2009 Member, Working Group on Interdisciplinary Research Groups (IRGs) and Interdisciplinary Research
Programs (IRPs), 2010-2011 University (Interdisciplinary Faculty Programs, Interdisciplinary Research Groups): Member, Executive Committee, Faculty of Toxicology, 1998-present Member, Faculty of Toxicology External Review Steering Committee, 1998-1999 Member, Executive Committee, Faculty of Reproductive Biology, 1999-2004; 2006-present Member, Faculty of Reproductive Biology, Graduate Programs Committee, 2003-2005 Chair, Faculty of Toxicology, 2005-2010 Duties include: a) oversight of administrative activities of faculty (i.e., IFT administrative office
(telephone, computer and software, supplies and small equipment) and staff salaries. Staff include a Program Assistant (100% effort), a Business Coordinator (15% effort) and a student worker); b) administrative oversight of applications/admissions of graduate students to Toxicology Program; c) administrative oversight of funding for Toxicology Seminar Series, Travel Awards (including 18 students to Society of Toxicology, Society of Environmental Toxicology and Chemistry, American Association for Cancer Research, Endocrine Society and Teratology Society, Keystone Conferences as well as attendance of 12 students to the Gulf Coast Chapter-Society of Toxicology); d) preparation of Annual Report of IFT to the Dean of Graduate Studies and Council of Participating Deans; e) Toxicology Seminar Series; g) Organization and scheduling of Annual Toxicology Graduate Student Forum (Dr. Weston Porter and Kim Daniel coordinate scheduling of venue and graduate student presentations;
Additional one-time duties: a) Preparation of 394 page Self-Study for External Review of the Toxicology Program in 2007; b) Organization and scheduling of Academic Program Review scheduled for May 6-9, 2007; c) Development of Outcomes Assessment Instrument and Core Competencies for the Interdisciplinary Faculty of Toxicology; d) Provide formal response to findings Academic Program Review to Office of Graduate Studies; e) Meet with Executive Vice President and Provost, Executive Associate Vice President for Research, Dean of Undergraduate Programs, Participating Deans, Assistant Dean of Graduate Studies and Dean, Office of Graduate Studies to review Academic Program Review; f) Obtained 2 new graduate student stipends through the Office of the Executive Vice President and Provost for IFT beginning Fall, 2007.
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Vice-Chair, Faculty of Toxicology, 2010-2014 Chair, Interdisciplinary Faculty of Reproductive Biology, 2010-2013
Duties include: a) Oversight of administrative activities of faculty and IFRB Standing and ad hoc Committees; b) Administrative oversight of funding for Reproductive Biology Seminar Series, Travel Awards to national and international meetings, and other trainee-focused enrichment activities; c) Preparation of Annual Report of IFRB to the Dean of Graduate Studies and Council of Participating Deans; d) Organization and scheduling of Annual Reproductive Biology Retreat, Retreat venue and catering; e) Assist with organization and scheduling of annual Dr. Raymond O. Berry Memorial Lecture; f) Collect information and prepare Spring and Fall IFRB Newsletters
Member, Faculty of Reproductive Biology, Seminar Committee, 2010-present Editor, IFRB Newsletter, 2010 - present Invited Presentations, Symposia, Colloquia and Named Lectures (since 2000 only).
“Animal Cloning with Somatic Cells.” Texas Tech University College of Agricultural Sciences and Natural Resources Symposium. February 23, 2000, Lubbock, TX.
“Animal Biotechnology on the Micrometer Scale.” Department of Animal Science and Food Technology, Texas Tech University, February 23, 2000, Lubbock, TX.
“Advances in Non-invasive Micrometer and Nanometer Scale Cellular/Tissue Vital Imaging.” CE Course Chairperson, Society of Toxicology Annual Meeting, March 19-23, 2000, Philadelphia, PA. Included in the CE course is “Real Time Statistical Analysis of Frequency Encoded Ca2+ Signals.”
“Automation in PC-based Vision Applications: Real-Time Data Acquisition and Analysis.” Center for Environmental and Rural Health, Texas A&M University, Second Annual Scientific Symposium, “Genomics and Proteomics: Innovations in Environmental Health Research.” May 23, 2000.
“Integrins and Extracellular Matrix Proteins at the Maternal/fetal Interface in Domestic Animals.” Molecular Approaches in Cell-Cell Adhesion Symposium, January 27, 2001, Institut für Anatomie, Universität GH Essen, Germany.
“Eavesdropping on Endometrial and Myometrial Cells at the Micrometer Scale.” 42nd Annual T.F. Bunkley Lectureship/14th Annual Resident Research Day/11th Annual Baker Society Meeting for 2001. Texas A&M University System Health Science Center, March 23-24, 2001, Temple, TX.
“Espying Cellular Injury on the Micrometer Scale.” Southwest Environmental Health Sciences Center, University of Arizona, May 16-18, 2001.
“Regulation of Intracellular Calcium Signaling in Myometrial Cells.” Center for Reproductive Biology, Washington State University and University of Idaho, June 14-17, 2001.
“Extracellular Matrix Proteins at the Maternal/Conceptus Interface in Domestic Animals.” Reproduction and Development Workshop, Baylor College of Medicine, March 21, 2002.
“Espying Cellular Injury Caused by Food-borne Toxins and Toxicants on the Micrometer Scale.” Texas Science Partnership (TSP) program of the Institute of Food Science and Engineering, March 27, 2002.
“Integrin-ECM Interactions and the Implantation Adhesion Cascade in Domestic Animals.” Department of Cell Biology & Biochemistry, and Reproductive Biology Seminar Series, Texas Tech University Health Sciences Center, April 24, 2002.
“Comparative Biology of Implantation in Sheep and Pigs,” Gordon Research Conference, Reproductive Tract Biology, June 30 - July 5, 2002, Connecticut College, New London, CT.
“Enhanced Focal Adhesion Assembly Reflects Increased Mechanosensation/mechanotransduction along the Maternal/conceptus Interface During Pregnancy in Sheep.” 8th International Conference on Extracellular Matrix of the Female Reproductive Tract. November 11-13, 2006, Maui, HI.
“Enhanced Focal Adhesion Assembly (3D Matrix Adhesions) Reflects Increased Mechanosensation/ Mechanotransduction along the Maternal/Conceptus Interface During Pregnancy in Sheep.” Institute of Biosciences & Technology, Houston, TX, April 5, 2007.
“Integration of Cellular Responses to Mechanical Forces of Pregnancy,” Reproductive Biology Forum, TAMU, October 26, 2007
“Integrating Advances in Optical Microscopy to Study Mechanisms of Cellular Injury and Mechanobiology of Pregnancy.” Department of Environmental and Radiological Health Sciences, Colorado State University,
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March 10, 2008. “Integration of Cellular Responses to Mechanical Forces of Pregnancy,” Gordon Research Conference on
Reproductive Tract Biology, Andover, NH, August 3-8, 2008. “Mechanobiology of Pregnancy,” Department of Physiology and Biomedical Engineering, Mayo Clinic College of
Medicine, September 26, 2008. “Integration of Cellular Responses to Mechanical Forces of Pregnancy,” Toxicology Seminar Series, TAMU
Interdisciplinary Faculty of Toxicology, September 14, 2009. “Mechanical Force-induced Cell Signaling in the Uterus,” Reproductive Biology Seminar Series, TAMU
Interdisciplinary Faculty of Reproductive Biology, February 5, 2010. “Mechanobiology of Pregnancy,” Keynote speaker for the Center for Reproductive Biology and Health Annual
Retreat, Penn State University, May 24-25, 2010. “Mechanical Signals Impact the Function and Effectiveness of Hormones, Growth Factors & Nutrition in the
Pregnant Uterus,” Exercise Physiology Seminar Series, TAMU, February 28, 2011. “Mechanical Signals Impact the Function and Effectiveness of Hormones, Growth Factors & Nutrition in the
Pregnant Uterus,” The 4th Special Biomodulation Symposium, Seoul National University, Seoul, Korea, May 16, 2011.
“Integrin Signaling in Pregnancy,” International Symposium on Maternal Nutrition and Fetal Development, China Agricultural University, Beijing, China, May 21, 2011.
“Integrating Advances in Optical Microscopy to Study Mechanisms of Cellular Injury and Mechanobiology of Pregnancy/Parturition, Wuhan Polytechnic University, Wuhan, China, May 24, 2011
“Mechanisms of Cellular Injury: a Cellulomics Approach,” Guangdong Institute of Animal Science, Changsha, China, May 26, 2011
“Integrating Advances in Optical Microscopy to Study Mechanisms of Cellular Injury and Mechanobiology of Pregnancy/Parturition, South China Agricultural University & Guangdong Academy of Agricultural Sciences, Ghangzhou, China, May 27, 2011.
“Integrating Advances in Optical Microscopy for Interdisciplinary Research and Education,” University Lecture Series, North Dakota State University, April 26, 2012.
“Eavesdropping on Animal Cells and Tissues at the Micrometer to Nanometer Scale,” Department of Animal Science, Center for Nutrition and Pregnancy and the Advanced Imaging and Microscopy Laboratory, North Dakota State University, April 27, 2012.
“Microscopy and Photonics in Cancer,” College of Pharmacy and Pharmaceutical Sciences, Florida A&M University, January 10, 2013.
Graduate Advisory Committee Service
Ricky Tarlton, M.S., Microbiology, 1979 William Fonzi, Ph.D., Microbiology, 1981 Linda Harper, M.S., Microbiology, 1981 Robert Nordgren, M.S., Veterinary Parasitology, 1981 Thomas Campbell, M.S., Microbiology, 1981 Beverly Engel, M.S., Microbiology, 1981 Kathleen Shupe, Ph.D., Biology, 1982 Leo Bernard, Ph.D., Oceanography, 1982 Gregory Winker, M.S., Geology, 1982 Gregory Doucette, M.S., Oceanography, 1982 Sherry Symank, M.S., Biology, 1982 Yuki Morris, M.S., Biology, 1982 Kathleen Rasmussen, M.S., Biology, 1983 Aaron Waxman, M.S., Biology, 1983 Randolph Fox, M.S., Animal Science, 1983 Steven Boyce, M.S., Microbiology, 1983 Timothy Seay, M.S., Microbiology, 1984 Tom Covington, M.S., Geology, 1984 Gary Burch, M.S., Geology, 1984
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John Morrill, Ph.D., Veterinary Microbiology, 1984 Ajay Rege, Ph.D., Microbiology, 1984 John Huchton, Ph.D., Animal Science, 1984 Ruth E. Lewis, Ph.D., Biology, 1985 Dana Gaddy Kurten, M.S., Biology, 1985 Philip A. Mitchell, M.S., Biology, 1985 Gayle Dienberg, M.S., Zoology, 1985 David Cunningham, M.S., Geology, 1985 Earl Scott Ray, M.S., Geology, 1985 Cynthia Cooper, Ph.D., Microbiology, 1985 Donald Welch, Ph.D., Microbiology, 1985 Lynne M. Divis, Ph.D., Chemistry, 1985 Michael Meyer, Ph.D., Oceanography, 1985 Mary L. Treat, M.S., Microbiology, 1986 Mark Tanner, M.S., Mechanical Engineering, 1986 Robert Jones, M.S., Mechanical Engineering, 1986 Tommy Sewall, Ph.D., Biology, 1987 Flamarion B. Diniz, Ph.D., Chemistry, 1987 Mary Helen Niemann, M.S., Geology, 1987 E. Gail Guynn, M.S., Mechanical Engineering, 1987 Felix D. Guerrero, Ph.D., Biochemistry, 1988 Thane Wibbels, Ph.D., Biology, 1988 William Kornicker, Ph.D., Oceanography, 1988 Mike Hibbs, Ph.D., Mechanical Engineering, 1988 Jane Ann Pruitt, Ph.D., Animal Science, 1988 Joseph Bennett, Ph.D., Chemistry, 1989 Elizabeth Chakachery, Ph.D., Mechanical Engineering, 1989 Shu Fen Weng, Ph.D., Biology, 1989 Daniel L. Tuttle, M.S., Animal Science, 1989 Lisa Stein, Ph.D., Veterinary Anatomy and Public Health, 1990 Robert Jones, Ph.D., Mechanical Engineering, 1990 Karen Biery, Ph.D., Doctoral candidate, Veterinary Physiology, 1990 Dickson Varner, M.S., Veterinary Anatomy, 1990 Ying Jia-Hsu, M.S., Veterinary Anatomy, 1990 Richard Kurten, Ph.D., Cell Biology, Baylor College of Medicine, 1991 Lori Nemec French, Ph.D., Veterinary Physiology and Pharmacology, 1991 Humberto A. Garces, Ph.D., Wildlife Fisheries Sciences, 1991 Germain Rivard, Ph.D., Veterinary Anatomy and Public Health, 1991 Michelle Aucoin, Ph.D., Veterinary Anatomy and Public Health, 1992 Anton Hoffman, Ph.D., Veterinary Anatomy and Public Health, 1992 Jamie C. Laurenz, Ph.D., Animal Science, 1992 Adelaide Brady, Ph.D., Animal Science, 1992 Lynn Carroll, Ph.D., Entomology, 1992 James R. Hawker, Jr., Ph.D., Veterinary Anatomy and Public Health, 1992 Barbara Johnson, Ph.D., Veterinary Pathobiology, 1992 Kara Fowler, M.S. Animal Science, 1992 Hugh Dookwah, Ph.D., Veterinary Anatomy and Public Health, 1993 John Murphy, Ph.D., Architecture, 1993 Jeanine Sherrier, Ph.D., Biology, 1993 Greg Hall, Ph.D., Veterinary Pathobiology, 1993 Michael Carvan, Ph.D., Veterinary Anatomy and Public Health, 1993 Matthew Schroeder, Ph.D., Veterinary Anatomy and Public Health, 1993 Xiaohong Wang, Ph.D., Veterinary Physiology and Pharmacology, 1993
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Criag Rowlands, Ph.D., Veterinary Physiology and Pharmacology, 1993 Makiko Suzuki, M.S., Animal Science, 1993 Elizabeth Santos, M.S., Veterinary Large Animal Medicine and Surgery, 1993 Charles B. Spainhour, Ph.D., Toxicology, 1994 Russell Bowes, Ph.D., Toxicology, 1994 Patricia Fernandez, Ph.D., Toxicology, 1994 Thomas Weber, Ph.D., Toxicology, 1994 Hong Liu, Ph.D., Toxicology, 1994 R. Hartford Bailey, Ph.D. Toxicology, 1994 Xiaolan Ou, Ph.D., Toxicology, 1994 Linda DeAnne Moore, Ph.D., Veterinary Physiology and Pharmacology, 1994 Ricardo DeAzambuja, Ph.D., Veterinary Physiology and Pharmacology, 1994 Sid Robert Garner, Ed.D., Educational Administration, 1994 Milton Thomas, Ph.D., Animal Science, 1994 Shawn Holt, Ph.D., Medical Microbiology and Immunology, 1994 Kathy Chaloupka, Ph.D., Toxicology, 1994 William H. Hanneman, Ph.D., Toxicology, 1995 Marie Legare, Ph.D., Veterinary Anatomy and Public Health, 1995 Scott Coonrod, Ph.D., Veterinary Physiology and Pharmacology, 1995 Jennifer Lippert, M.S., Animal Science, 1995 Jana Echols, M.S., Veterinary Anatomy and Public Health, 1995 Kathy Nodlin, Ph.D., Veterinary Pathobiology, 1995 Nan L. Wavra, M.S., Physiology of Reproduction, 1995 Michael Moore, Ph.D., Toxicology, 1995 Thomas Spencer, Ph.D., Physiology of Reproduction, 1995 Yufang Lu, Ph.D., Toxicology, 1995 Jill Hiney, Ph.D., Veterinary Anatomy and Public Health, 1996 Susan Miller, Ph.D., Veterinary Anatomy and Public Health, 1996 Yi-Hai Jang, Ph.D., Animal Science, 1996 Yang-Yi Fan, Ph.D., Animal Science, 1996 Robert Drolosky, Ph.D., Veterinary Pathobiology, 1996 Jeff Bowen, Ph.D., Veterinary Anatomy and Public Health, 1996 Wei Zhao, Ph.D., Toxicology, 1996 Kevin Connor, Ph.D., Toxicology, 1996 Yong Zhang, Ph.D., Toxicology, 1996 Westin Porter, Ph.D., Toxicology, 1996 Christopher Dekaney, M.S., Veterinary Anatomy and Public Health, 1996 Elisabeth Zenger, Ph.D., Veterinary Anatomy and Public Health, 1997 Alan Parrish, Ph.D., Toxicology, 1997 Fan Wang, Ph.D., Toxicology, 1997 Olga Leticia Johnson, Ph.D., Toxicology, 1997 Wen-Chi Chang, Ph.D., Animal Science, 1997 Matthew Reed, Ph.D., Medical Pharmacology and Toxicology, 1997 Wendy Dippel, Ph.D., Physiology of Reproduction, 1997 Win-Chi Chen, Ph.D., Animal Science, 1997 Shyh-hwa Liu, Ph.D., Physiology of Reproduction, 1997 Debra L. Zoran, Ph.D., Animal Science, 1997 Gayla Combes, M.S., Veterinary Large Animal Medicine and Surgery, 1997 Richard Hutchinson, D.V.M., 1996; Ph.D., Veterinary Anatomy and Public Health, 1998 Anupama Gupta, Ph.D., Veterinary Anatomy and Public Health, 1998 Kendall Russell DePriest, M.S., Health Physics, 1999 Jeannine Botos, Ph.D., Veterinary Physiology and Pharmacology, 1999 Jonathan Hill, Ph.D., Veterinary Physiology and Pharmacology, 1999
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Nan Kemper Greene, Ph.D., Physiology of Reproduction, 1999 Regina Weaks, M.S., Veterinary Anatomy and Public Health, 1999 Michael Hofle, M.S., Veterinary Pathobiology, 1999 Renqin Duan, Ph.D., Toxicology, 1999 Janida Lanet Rice, Ph.D., Psychology, 1999 Lora Ann Schneider, Ph.D., Veterinary Anatomy and Public Health, 1999 Deepani K. Tennakoon, Ph.D., Veterinary Anatomy and Public Health, 1999 Katherine Springman, Ph.D., Toxicology, 1999 Mona Sethi Gupta, Ph.D., Toxicology, 1999 I-Chen Chen, Ph.D., Toxicology, 1999 Marlene Man-ling Hsieh, Ph.D., Veterinary Pathobiology, 2000 Kim Liu, Ph.D., Toxicology, 2000 Yun-Houng Chen, Ph.D., Toxicology, 2000 Gulan Sun, Ph.D., Toxicology, 2000 Kevin Kerzee, Ph.D., Toxicology, 2000 Allison Gray, M.S., Physiology of Reproduction, 2000 ChangKyu Lee, Ph.D., Physiology of Reproduction, 2000 Sonya Derczo, M.S., Physiology of Reproduction, 2000 Chen Chen, M.S., Physiology of Reproduction, 2000 Carrie Vyhladal, Ph.D., Biochemistry, 2001 Hakhyun Ka, Ph.D., Physiology of Reproduction, 2001 Wen Xie, Ph.D., Toxicology, 2001 Sean Ottinger, Ph.D., Toxicology, 2001 Raquel Cossio-Bayugar, Ph.D., Veterinary Pathobiology, 2001 Carol Hanna, M.S., Veterinary Physiology & Pharmacology, 2001 M. David Stewart, M.S., Physiology of Reproduction, 2001 Russell Depriest, PhD., Nuclear Engineering, 2001 Tae-Hyeon Cho, Ph.D., Toxicology, 2001 Lisa Sanders, M.S. Nutrition, 2001 Cara Everett Henderson, M.S., Nutrition, 2001 Renato de Lima-Santos, Ph.D., Veterinary Pathobiology, 2001 Jane Garlow, M.S., Physiology of Reproduction, 2002 Bharati Hegde, M.S., Biomedical Engineering, 2002 Kimberly Miller, Ph.D., Toxicology, 2002 Youngsok Choi, Ph.D., Physiology of Reproduction, 2002 M. Hadi Falahatpisheh, Ph.D., Toxicology, 2002 Matthew Stoner, Ph.D., Toxicology, 2002 Mark Wormke, Ph.D., Toxicology, 2002 Cara Benjamin, Ph.D., Genetics, 2002 Sekoni Noel, M.S., Physiology of Reproduction, 2002 Kathryn Johnston Brown, Ph.D. Ed Admin. & Human Resource Develop, 2003 Spencer Williams, Ph.D. Toxicology, 2003 Roberto L. Gorena, Ph.D., Entomology, 2003 Steven Holmes, Ph.D., Entomology, 2003 Kelcey Walker, Ph.D., Toxicology, 2004 Joshua Neunuebel, M.S., Biology, 2004 Natalia Medvedeva, Ph.D., Nuclear Engineering, 2004 Jeongmin Seo, Ph.D., Nutrition, 2004 KyoungHyun Kim, Ph.D., Toxicology, 2004 Melinda Wiles, Ph.D., Toxicology, 2004 Jeong-Eun Lee, Ph.D., Toxicology, 2004 Lisa Sanders, Ph.D., Nutrition, 2005 Karen Carpenter, Ph.D., Physiology of Reproduction, 2005
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C. Allison Gray, Ph.D., Physiology of Reproduction, 2005 Vandana Sarin, Ph.D., Medical Physiology, 2005 Marisa Pulido Covington, Ph.D., Medical Pharm & Tox, 2005 Xiangrong Li, Ph.D., Toxicology, 2005 Tamy Frank, Ph.D. Ph.D.,Veterinary Integrative Biosciences, Ph.D., 2005 Shaheen Khan, Ph.D., Genetics, 2005 Charile Partridge, Ph.D., Toxicololgy, 2006 Sudahakar Chintharlapalli, Ph.D., Toxicology, 2006 Katherine Dunlap, Ph.D., Physiology of Reproduction, 2006 George J. Hager, Ph.D., Chemistry, 2006 Lance Roasa, M.S., Veterinary Physiology & Phamacology Wan-Ru Lee, Ph.D., Toxicology, 2006 Hyeong-Il Kwak, Ph.D., Toxicology, 2006 Jiney Jose, M.S., Chemistry, 2006 Chien-Chang Chen, Ph.D., Toxicology, 2006 Leela Kotha, Ph.D. Toxicology, 2006 Wang-Ru Lee, Ph.D., Toxicology, 2006 Gang Chen, Ph.D., Systems Biology & Translational Medicine, 2006 Josely Figueiredo, Ph.D., Veterinary Pathobiology, 2006 Kathryn Vanderlaag, Ph.D., Toxicology, 2007 Melissa York, M.S., Toxicology, 2007 Gwonhwa Song, Ph.D., Physiology of Reproduction, 2007 Erica D. Bruce, Ph.D., Civil Engineering, 2007 Saeed Y. Al-Ramadan, Ph.D. Veterinary Anatomy, 2007 Satya Sree Kolar, Ph.D., Nutrition, 2007 Kimberly Cox, M.S., Biology, 2007 Fei Wu, Ph.D., Toxicology, 2007 Jairo E. dos S. Nunes, Ph.D., Veterinary Pathobiology, 2007 Shu Zhang, Ph.D., Toxicology, 2008 Kimberly Cox, M.S., Biology, 2008 Hyowon Ahn, M.S., Physiology of Reproduction, 2008 Carey Satterfield, Ph.D., Physiology of Reproduction, 2008 Sabitha Papineni, Ph.D., Toxicology, 2008 Ying Xie, Ph.D., Toxicology, 2008 Adebayo Akintola, Ph.D., Medical Sciences, 2008 Jennifer Farmer, Ph.D. Physiology of Reproduction, 2008 Margaret Joyce, Ph.D., Biomedical Sciences (Reproductive Biology), 2008 Hiromi Hosako, Ph.D., Toxicology, 2008 Lauri Willingham-Rocky, Ph.D., Veterinary Anatomy, 2008 Dana Dean, Ph.D., Biomedical Sciences, 2008 Adam Larson, Ph.D., Biomedical Engineering, 2008 Stacy Sherrod, Ph.D., Chemistry, 2008 Arantzazu Lassala, Ph.D., Physiology of Reproduction, 2008 Zara Berg, M.S. Toxicology, 2008 Todd Stroud, M.S., Veterinary Physiology & Pharmacology, 2009 Jeff Burkeen, M.S., Biology, 2009 Yuichiro Ueno, Ph.D., Chemistry, 2009 Haijun Gao, Ph.D. Physiology of Reproduction, 2009 Shaye K. Lewis, Ph.D., Physiology of Reproduction, 2009 Elizabeth Wellberg, Ph.D., Toxicology, 2009 Quynh Tien Ngoc Tran, Ph.D., Veterinary Pathobiology, 2009 Christopher Jagge, Ph.D., Entomology, 2009 Dana Massuto, Ph.D., Biomedical Sciences, 2009
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Jiney Josey, Ph.D., Chemistry, 2009 Ying Xie, Ph.D., Toxicology, 2009 Huajun He, M.S., Biotechnology, 2009 Rebecca Simmons, M.S., Physiology of Reproduction, 2009 Jinyoung Kim, Ph.D., Physiology of Reproduction, 2010 Sarah Black, Ph.D., Physiology of Reproduction, 2010 Nivedita Banerjee, M.S. Toxicology, 2010 Carolyn Allen, M.S., Physiology of Reproduction, 2010 Xilong Li, Ph.D., Nutrition, 2011 Lesley Gardiner, M.D., Ph.D., Syst Biol Transl Med, 2012 Sarah M. Lane, M.S., Chemistry, 2012 Aaron Guthrie, M.S., Toxicology, 2012 Satya Sreehari Pathi, Ph.D., Toxicology, 2012 Harmony Turk, Ph.D., Nutrition, 2012 Michael Eller, Ph.D., Chemistry, 2012 JeHoon Lee, Ph.D., Biomedical Sciences, 2013 Sandeep Sreevalsan, Ph.D., Toxicology, 2013 Gabriel Gomez, Ph.D. Veterinary Pathobiology, 2013 Gregory A. Johnson, Ph.D. Biochemistry, 2013 Amanda H. Vorpahl, M.S., Biotechnology, 2013 Theodore Wing, M.S., Biomedical Sciences, 2013 Kiran Ramchandani, M.S, Biotechnology, 2014 Grace Chang, M.S., Biomdical Sciences, 2014 Bruno Peña, Ph.D., Chemistry, 2014 Atashi Mukherjee, Ph.D., Chemistry, 2014 Xi Li, Ph.D., Medical Physiology, 2014
Vijay Vansanthakumari, Ph.D., Toxicology, 2014 Harini Sreenivasappa, Ph.D., Biomedical Engineering, 2014 David Morris, Ph.D., Veterinary Pathobiology, 2015 Paula Castillo, M.S., Entomology, 2015 James Frank, Ph.D., Biomedical Sciences, 2015 Chelsie Burroughs Steinhouser, Ph.D. Biomedical Sciences, 2015 Xiaoqiu Wang, Ph.D., Physiology of Reproduction, 2015 (262)