CURRICULUM VITAE The Johns Hopkins University School of Medicine

__________________________________ July 23, 2014 Amita Gupta, M.D., M.H.S. DEMOGRAPHIC AND PERSONAL INFORMATION Current Appointments Primary Appointment Associate Professor, Division of Infectious Diseases, Department of Medicine The Johns Hopkins University School of Medicine Secondary Appointment Associate Professor, Department of International Health The Johns Hopkins Bloomberg School of Public Health Personal Data:

Business Address The Johns Hopkins University School of Medicine Division of Infectious Diseases, Department of Medicine

Center for Clinical Global Health Education 600 N. Wolfe Street, Phipps 540 Baltimore, Maryland 21287 Phone: 410-502-7696 Fax: 443-287-6440 Email: agupta25@jhmi.edu

Education and Training

Undergraduate 1987-1991 B.Sc., Materials Science & Engineering

Massachusetts Institute of Technology Cambridge, Massachusetts

Doctoral/graduate

1992-1997 M.D. Harvard Medical School Boston, Massachusetts

Postdoctoral

1997-2000 Internal Medicine-Primary Care/Internship/Residency Medicine, University of California San Francisco San Francisco General Hospital San Francisco, California

2000-2002 Epidemic Intelligence Service Centers for Disease Control and Prevention

Foodborne and Diarrheal Diseases Branch Atlanta, Georgia

Page 1

2004-2005 Post Doctoral Fellowship, Infectious Diseases The Johns Hopkins University School of Medicine Baltimore, Maryland

2005-2006 Masters in Health Sciences, Clinical Investigation Johns Hopkins Bloomberg School of Public Health Baltimore, Maryland

Professional Experience

1988 Research Assistant, Genetic engineering laboratory Ciba-Geigy Basel, Switzerland 1989 Research Assistant, Liquid hydrogen technology division Air Products, Inc. Uxbridge, England

1990 Research Assistant, Polymer division Undergraduate Thesis Project Rohm & Haas European Laboratories, Valbonne, France

1991-1992 Public Health Officer, AIDS Bureau Massachusetts Department of Public Health Boston, Massachusetts

1992-1994 HIV Counselor AIDS Action Committee

Boston, Massachusetts

1993 HIV Women’s Health Policy Consultant The Medical Foundation

Boston, Massachusetts

1993-1994 Health Outreach Worker Rosie’s Place (women’s homeless shelter) Harvard Urban Health Fellowship

Boston, Massachusetts

1995 Primary Care Medical Training Alaskan Native American Health Service (SEARHC) Sitka, Alaska

1996 Perinatal and Early Infant Mortality Research Francisco Marroquin Medical School and Centro CEMI San Juan Sacatepequez, Guatemala 1997 Breast and Cervical Cancer Outcomes Research Department of Health Care Policy Harvard Medical School

Boston, Massachusetts

Page 2

1999-2000 Primary Care Outcomes Research San Francisco General Hospital

San Francisco, California 2000-2002 Medical Epidemiologist Foodborne and Diarrheal Diseases US Centers for Disease Control and Prevention Atlanta, Georgia 2002-2003 Clinical Associate, Division of Infectious Diseases The Johns Hopkins University School of Medicine

Baltimore, Maryland

2003-2004 Instructor, Division of Infectious Diseases Department of Medicine The Johns Hopkins University School of Medicine

Baltimore, Maryland

2004-present Deputy Director Johns Hopkins Center for Clinical Global Health Education The Johns Hopkins University School of Medicine Baltimore, Maryland

2005-2011 Assistant Professor, Division of Infectious Diseases Department of Medicine

The Johns Hopkins University School of Medicine Baltimore, Maryland

2010-2011 Assistant Professor, Department of International Health The Johns Hopkins Bloomberg School of Public Health

Baltimore, Maryland

2011-present Associate Professor, Division of Infectious Diseases Department of Medicine The Johns Hopkins School of Medicine and Department of International Health The Johns Hopkins Bloomberg School of Public Health Baltimore, Maryland

RESEARCH ACTIVITIES Publications: Peer-Reviewed Original Science Research

1. Scharfstein J, Gupta A. Confidentiality of radiologic images. Radiology 1995;195(3):873-4. 2. Gupta A, Kalluri P, Painter J, Zansky S, Wallace B, Schoonmaker-Bopp D, Smith P, Ramsey F. Outbreak

of multidrug resistant Salmonella Newport – United States, January-April 2002. MMWR 51(25), June 28, 2002. Also published in JAMA 2002; 288(8).

3. Gupta A, Crowe, C, Bolstorff B, Fontana J, Stout A, Montgomery S, McGuill M, Matyas B, Johnson B,

Schoenfeld S, Angulo FJ. The Emergence of Newport MDR-AmpC, highly resistant strains of Salmonella Newport in the United States. J Infect Dis 2003; 188:1707-16.

Page 3

4. Bollinger RC, Gupta A. GBV-C: A virus in search of a disease or a role in HIV therapy? Clin Infect Dis 2004; 38(3):410-1.

5. Olsen SJ, Pruckler J, Bibb W, My Thanh NT, My Trinh N, Minh NT, Sivapalasingam S, Gupta A, Phuong

PT, Chinh NT, Chau NV, Cam PD, and Mintz ED. Evaluation of rapid diagnostic tests for typhoid fever. J Clin Micro 2004; 42(5):1885-9.

6. Gupta A, Polyak C, Bishop R, Sobel J, Mintz ED. Shigellosis in the United States, 1989-2002. Clin Infect

Dis 2004; 38:1372-76. 7. Gupta A, Nelson JM, Barrett TJ, Tauxe RV, Rossiter SP, Friedman CR, Joyce KW, Smith KE, Jones TF,

Hawkins MA, Shiferaw B, Beebe JL, Vugia DJ, Rabatsky-Ehr T, Benson JA, Root TP, Angulo FJ. Fluoroquinolone-resistant Campylobacter jejuni infections in the United States, 1997-2001. Emerg Infect Dis 2004; 10(6):1102-09.

8. Gupta A, Hunter SB, Bidol SA, Dietrich S, Kincaid J, Salehi E, Nicholson L, Genese CA, Todd-

Weinstein S, Marengo L, Kimura AC, Brooks JT. Escherichia coli O157 cluster evaluation. Emerg Infect Dis 2004; 10(10):1856-8.

9. Isaacs S, Aramini J, Ceibin B, Farrar J, Ahmed R, Middleton D, Howes M, Chan E, Pichette S, Campell K,

Gupta A, Lior LY, Pearce M, Clark C, Rodgers F, Jamieson F, Brophy I, Ellis A. An international outbreak of salmonellosis associated with raw almonds contaminated with a rare phage type of Salmonella enteriditis. J Food Prot 2005; 68(1):191-8.

10. Eshleman SH, Hudelson S, Gupta A, Bollinger R, Divekar AD, Gangakhedkar RR, Kulkarni SS, Thakar

MR, Paranjape RS, and Tripathy S. Limited evolution in the HIV-1 pol region among acute seroconverters in Pune, India. AIDS Res Hum Retroviruses 2005; 21(1):93-7.

11. Jain S, Gupta A, Glanz B, Dick J, Siberry G. Antimicrobial-resistant Shigella sonnei: Limited

antimicrobial treatment options for children and challenges of interpreting in vitro azithromycin susceptibility. Pediatr Infect Dis J 2005; 24(6):494-7.

12. Sobel J, Mixter CG, Kohle PK, Gupta A, Guarner J, Zaki S, Hoffman NA, Songer JG, Fremont-Smith M,

Fischer M, Killgore G, Britz PH, MacDonald C. Necrotizing enterocolitis associated with Clostridium perfringens type A in previously healthy North-American adults. J Am Coll Surg 2005; 201(1):48-56.

13. Gupta A, Sumner CJ, Castor M, Sobel, J. Adult botulism type F in the United States, 1981-2002.

Neurology 2005; 65(11):1694-700. 14. Mehta S, Gupta A, Sahay S, Godbole SV, Reynolds SJ, Celentano DD, Risbud A, Mehendale SM ,

Bollinger RC. High HIV prevalence among a high-risk subgroup of women attending sexually transmitted infection (STI) clinics in Pune, India. J Acquir Immune Defic Syndr 2006; 41(1)75-80.

15. Mehendale SM, Kishore Kumar B, Ghate MV, Sahay S, Gamble T, Godbole SV, Gupta A, Gangakhedkar

RR, Divekar AD, Risbud AR, Paranjape RS, Bollinger RC. Low HIV-1 Incidence among married serodiscordant couples in Pune, India. J Acquir Immune Defic Syndr 2006; 41(3):371-3.

16. Gupta A, My Thanh NT, My Trinh T, Olsen SJ, Sivapalasingam S, Cam PD, Mintz ED. Evaluation of

serologic screening for identification of chronic Salmonella typhi carriers in Vietnam. Int J Infect Dis 2006; 10(4):309-14.

Page 4

17. Gupta A, Mehta S, Godbole SV, Sahay S, Walshe L, Reynolds SJ, Ghate M, Gangakhedkar RR, Divekar AD, Risbud AR, Mehendale SM, Bollinger RC. Same-sex behavior and high rates of HIV among men attending sexually transmitted infection clinics in Pune, India, 1993 through 2002. J Acquir Immune Defic Syndr 2006; 43(4):483-90.

18. Ramachandani S, Mehta S, Saple DG, Vaidya SB, Pandey VP, Vadrevu R, Rajasekaran S, Bhatia V,

Chowdhary A, Bollinger RC, Gupta A. Knowledge, attitudes, and practices of antiretroviral therapy among adults attending private and public clinics in India. AIDS Patient Care STDs 2007; 21(2):55-68.

19. Polis C, Shah S, Johnson K, Gupta A. Impact of maternal HIV co-infection on the vertical transmission of

Hepatitis C virus: a meta-analysis. Clin Infect Dis 2007; 44(8) 1123-31. 20. Shah B, Walshe L, Saple DG, Ramini R, Kharkar S, Bollinger RC, Gupta A. Adherence to antiretroviral

therapy and virologic suppression among HIV-infected persons receiving care in private clinics in Mumbai, India. Clin Infect Dis 2007; 44(9)1235-44.

21. Sinha G, Choi J, Nayak U, Gupta A, Nair S, Gupte N, Bulakh PM, Sastry J, Deshmukh SD, Khandekar

MM, Bhore AV, Melinkeri RR, Kulkarni VP, Bhosale RA, Naphade PR, Bharucha KE, Phadke MA, Kshirsagar AS, Bollinger RC. Clinically-significant anemia in HIV-infected pregnant women in India is not a major barrier to zidovudine use for prevention of maternal-to-child transmission. J Acquir Immune Defic Syndr 2007; 45:210-7

22. Gupta A, Nayak U, Ram M, Bhosale R, Patil S, Basavraj A, Kakrani A, Phillip S, Desai D, Sastry J,

Bollinger R, for the Byramji Jeejeebhoy Medical College-Johns Hopkins University Study Group. Post-partum TB incidence and mortality among HIV-infected women and their infants in Pune, India 2002-2005. Clin Infect Dis 2007; 45:241-9.

23. Sobhani RM, Basavaraj A, Gupta A, Bhave AS, Kadam DB, Sangle SA, Prasad HB, Choi J, Josephs J,

Gebo KA, Morde SN, Bollinger RC, Kakrani AL. Inpatient mortality, clinical characteristics and length of stay among HIV-infected persons attending a public hospital in Pune, India. Indian J Med Res 2007; 126:112-7.

24. Gupta A, Sastry J, Suryawanshi N, Pisal H, Kulkarni P, Bharucha KE, Bulakh P, Gupte N, Krisagar A,

Tripathy S, Paranjape R, Bhore AV, Ambike N, Choi J, Nayak J, Phadke M, Bollinger RC. Mother-to-child transmission of HIV among women who chose not to exclusively breastfeed their infants in Pune, India. Ind J Med Res 2007; 126(2): 131-4.

25. Gupta A, Gupte N, Bhosale R, Kakrani A, Kulkarni V, Nayak U, Thakar M, Sastry J, Bollinger RC; for

the Byramji Jeejeebhoy Medical College-Johns Hopkins University Study Group. Low sensitivity of total lymphocyte count as a surrogate marker to identify antepartum and postpartum Indian women who require antiretroviral therapy. J Acquir Immune Defic Syndr 2007; 46(3): 338-42.

26. Passaretti C, Gupta A. Selenium and HIV: Hope or hype? Arch Intern Med 2007; 167(22) 2530-31,

(Comment on Hurwitz BE, Arch Intern Med 2007; 167(2):148-54). 27. Six Week Extended-Dose Nevirapine (SWEN) Study Team, Bedri A, Gudetta B, Isehak A, Kumbi S,

Lulseged S, Mengistu Y, Bhore AV, Bhosale R, Varadhrajan V, Gupte N, Sastry J, Suryavanshi N, Tripathy S, Mmiro F, Mubiru M, Onyango C, Taylor A, Musoke P, Nakabiito C, Abashawl A, Adamu R, Antelman G, Bollinger RC, Bright P, Chaudhary MA, Coberly J, Guay L, Fowler MG, Gupta A, Hassen E, Jackson JB, Moulton LH, Nayak U, Omer SB, Propper L, Ram M, Rexroad V, Ruff AJ, Shankar A, Zwerski S. Extended-dose nevirapine to 6 weeks of age for infants to prevent HIV transmission via breastfeeding in Ethiopia, India, and Uganda: an analysis of three randomized controlled trials. Lancet 2008; 372(9635):300-13.

Page 5

28. Fritts M, Crawford CC, Quibell, D, Gupta A, Jonas WB, Coulter ID, Andrade, A. Traditional Indian medicine and homeopathy for HIV/AIDS: a review of the literature. AIDS Res Therapy 2008, 5:25. PMCID: PMC2637286

29. Singh HK, Gupta A, Siberry GK, Gupte N, Sastry J, Kinikar A, Shah I, Gangakhedkar RR, Bollinger RC,

Kulkarni V. The Indian pediatric HIV epidemic: a systematic review. Curr HIV Res 2008; 6:419-32. 30. Gupta A, Anand S, Sastry J, Krisagar A, Basavaraj A, Bhat, SM, Gupte N, Bollinger RC, Kakrani AL.

High risk for occupational exposure to HIV and utilization of post-exposure prophylaxis in a teaching hospital in Pune, India. BMC Infect Dis 2008, 8:142. PMCID:PMC2588594.

31. Moorthy A, Gupta A, Bhosale R, Tripathy S, Sastry J, Kulkarni S, Thakar M, Bharadwaj R, Kagal A,

Bhore AV, Patil S, Kulkarni V, Varadharajan V, Balasubramaniam U, Suryavanshi N, Ziemniak C, Gupte N, Bollinger R, Persaud D. Nevirapine resistance and breast-milk HIV transmission: effects of single and extended-dose nevirapine prophylaxis in subtype C HIV-infected infants. PLoS One 2009:4(1):e4096. PMCID:PMC2606064.

32. Gupta A, Saple D, Nadkarni G, Shah B, Vaidya S, Hingankar N, Chaturbhuj D, Deshmukh P, Walshe L,

Hudelson S, James M, Paranjape R, Eshleman S, Tripathy S. One-, two-, and three-class resistance among HIV-infected patients on antiretroviral therapy in private care clinics: Mumbai, India. AIDS Res Hum Retroviruses 2010; 26(1):25-31.PMCID:PMC2858895.

33. Walshe L, Saple DG, Shah B, Mehta SH, Bollinger RC, Gupta A. Physician estimate of antiretroviral

adherence: Poor correlation with patient self-report and viral load. AIDS Patient Care STDs 2010; 24(3):189-95.PMCID: PMC2864050.

34. Marais B, Gupta A, Starke JR, El Sony A. Tuberculosis in women and children. Lancet 2010; 375(9731):

2057-9. 35. Gupta A, Sane S, Gurbani A, Bollinger, RC, Mehendale S, Godbole S. Stigmatizing attitudes and low

levels of knowledge but high willingness to participate in HIV management: A community based survey of pharmacies in Pune, India. BMC Public Health 2010; 10:517.PMCID: PMC2939646.

36. Gupta A, Bhosale R, Kinikar A, Gupte N, Bharadwaj R, Kagal A, Joshi S, Khandekhar M, Karmarkar A,

Kulkarni V, Sastry J, Mave V, Suryavanshi N, Thakar M, Kulkarni S, Tripathy S, Sambarey P, Patil S, Paranjape R, Bollinger RC and Jamkar A, for the SWEN India Study Team. Maternal tuberculosis: a risk factor for HIV mother-to-child transmission. J Infect Dis 2011; 203(3):358-62.PMCID:PMC3071111.

37. Six Week Extended-Dose Nevirapine (SWEN) Study Team, Bedri A, Gudetta B, Isehak A, Kumbi S,

Lulseged S, Mengistu Y, Bhore AV, Bhosale R, Varadhrajan V, Gupte N, Sastry J, Suryavanshi N, Tripathy S, Mmiro F, Mubiru M, Onyango C, Taylor A, Musoke P, Nakabiito C, Abashawl A, Adamu R, Antelman G, Bollinger RC, Bright P, Chaudhary MA, Coberly J, Guay L, Fowler MG, Gupta A, Hassen E, Jackson JB, Moulton LH, Nayak U, Omer SB, Propper L, Ram M, Rexroad V, Ruff AJ, Shankar A, Zwerski S. 12 month follow-up of SWEN RCTs: Differential impact of extended-dose nevirapine on MTCT and infant death by maternal CD4 cell count. AIDS 2011; 25:767-76.

38. Bollinger RC, McKenzie-White J, Gupta A. Building a global health education network for clinical care

and research; the benefits and challenges of distance learning tools; lessons learned from the Hopkins Center for Clinical Global Health Education. Infect Dis Clin of North Am 2011; 25(2)385-98. PMCID:PMC3107515.

Page 6

39. Patil S, Bhosale R, Sambarey P, Gupte N, Suryavanshi N, Sastry J, Bollinger RC, Gupta A, Shankar A. Impact of maternal human immunodeficiency virus infection on pregnancy and birth outcomes in Pune, India. AIDS Care 2011 Dec; 23(12):1562-9.

40. Singh HK, Gupte N, Kinikar A, Bharadwaj R, Sastry J, Suryavanshi N, Nayak U, Tripathy S, Paranjape R,

Jamkar A, Bollinger RC, Gupta A and the SWEN India Study Team. High rates of all-cause and gastroenteritis-related hospitalization morbidity and mortality among HIV-exposed Indian infants. BMC Infect Dis 2011 Jul; 11(1):193. PMCID:PMC3161884.

41. Cohen MS, Chen YQ, McCauley M, Gamble T, Hosseinipour MC, Kumarasamy N, Hakim JG,

Kumwenda J, Grinsztejn B, Pilotto JH, Godbole SV, Mehendale S, Chariyalertsak S, Santos BR, Mayer KH, Hoffman IF, Eshleman SH, Piwowar-Manning E, Wang L, Makhema J, Mills LA, de Bruyn G, Sanne I, Eron J, Gallant J, Havlir D, Swindells S, Ribaudo H, Elharrar V, Burns D, Taha TE, Nielsen-Saines K, Celentano D, Essex M, Fleming TR; HPTN 052 Study Team. Prevention of HIV-1 infection with early antiretroviral therapy. N Engl J Med 2011 Aug; 365(6):493-505.PMCID: PMC3200068

42. Gupta A, Chandrasekhar A, Gupte N, Patil S, Bhosale R, Sambarey P, Ghorpade S, Nayak U, Garde L, Sastry J, Bharadwaj R, Bollinger RC on behalf of the BJ Medical College-Johns Hopkins University Study Group. Symptom screening among HIV-infected pregnant women is acceptable and has high negative predictive value for active tuberculosis. Clin Infect Dis 2011 Nov; 52(10):1015-8. PMCID: PMC193828

43. Gupta A, Nadkarni N, Yang W-T, Chandrasekhar A, Gupte N, Bisson GP, Hosseinipour M, Gummadi N.

Early mortality in adults initiating antiretroviral therapy (ART) in low- and middle-income countries (LMIC): a systematic review and meta-analysis. PLoS ONE Dec 2011; 6(12):e28691. PMCID: PMC3248405

44. Chandrasekhar A, Gupta A. Nutrition and disease progression pre- highly active antiretroviral therapy

(HAART) and post-HAART: Can good nutrition delay time to HAART and affect response to HAART? Invited Review Am J Clin Nutr 2011 Dec; 94(6):1703S-15S. PMCID: PMC3226023

45. Mave V, Kulkarni V, Bharadwaj R, Kandekar M, Gupta A, Gupte N. Determination of a reference

interval in a population. Natl Med J India 2012; Jan-Feb 25(1):33-4.

46. Sahastrabudddhe S, Gupta A, Stuart EA, Godbole S, Ghate M, Sahay S, Gangakhedkar R, Risbud A, Divekar A, Bollinger R, Mehendale SM. Sexually transmitted infections and risk behaviors among transgender persons (Hijras) of Pune, India. J Acquir Immun Def Syndr 2012 Jan; 50(1):72-8.

47. Kinikar AA, Kulkarni RK, Valvi CT, Mave V, Gupte N, Khadse S, Bharadwaj R, Kagal A, Puranik S,

Gupta A, Bollinger R, Jamkar A. Predictors of mortality in hospitalized children with pandemic H1N1 influenza 2009 in Pune, India. Indian J Pediatr 2012; Apr; 79(4):459-66.

48. Dooley KE, Park J-G, Swindells S, Allen R, Haas DW, Aweeka F, Gupta A, Lizak P, Qasba S, Cramer Y,

van Heeswijk R, Flexner C. Safety, tolerability, and pharmacokinetic interactions between single-dose TMC207 and steady-state efavirenz in healthy volunteers: AIDS Clinical Trials Group (ACTG) Study. J Acquir Immune Defic Syndr 2012 Apr; 15; 59(5):455-62. PMCID: PMC3302922

49. Mave V, Shere D, Gupte N, Suryavanshi N, Kulkarni V, Patil S, Khandekar M, Kinikar A, Bharadwaj R,

Bhosale R, Sambarey P, Chandanwale A, Bollinger R, Gupta A. Vitamin D deficiency is common among HIV-infected breastfeeding mothers in Pune, India, but not associated with mother-to-child HIV transmission. HIV Clin Trials 2012; 13(5):278-83.

Page 7

50. Balagopal A, Gama L, Franco V, Russell JN, Smeaton LM, Clements JE, Thomas DL, Gupta A. Detection of microbial translocation in HIV and SIV infection using the limulus amebocyte lysate assay is masked by serum and plasma. PLoS ONE 2012; 7(8):e41258.PMCID:PMC3409852

51. Mathad J, Gupta A. Tuberculosis in pregnant and postpartum women: Epidemiology, management, and

research gaps. Clin Infect Dis 2012 Dec, 55(11):1532-49.PMCID:PMC3491857

52. Arora N, Vadrevu R, Chandrasekhar A, Gupta A. Low tuberculosis knowledge among HIV-infected patients in a high HIV prevalence region within Southeast India. J Int Assoc Phys 2012 Apr, 12(2):84-9.

53. Ram M, Gupte N, Nayak U, Kinikar A, Khandave M, Shankar A, Sastry J, Bollinger R, Gupta A. Growth

patterns among HIV-exposed infants receiving nevirapine prophylaxis in Pune, India. BioMed Central Infect Dis 2012; 12:282, doi: 10.1186/1471-2334-12-282. PMCID:PMC3556061

54. Swindells S, Komarow L, Tripathy S, Cain KP, MacGregor RR, Achkar JM, Gupta A, Veloso VG,

Asmelash A, Omoz-Oarhe AE, Gengiah S, Lalloo U, Allen R, Shiboski C, Anderson J, Qasba SS, Katzenstein DK for the AIDS Clinical Trials Group A5253 Study Team. Screening for pulmonary tuberculosis in HIV-infected individuals: AIDS Clinical Trials Group Protocol A5253. Int J Tuberc Lung Dis 2013;17(4):532-9. PMCID: PMC3923622

55. Sugarman J, Bhan A, Bollinger R, Gupta A. Unintended consequences of a new Indian policy to protect

participants. BMJ 2013 Jul 31;347:f4841.doi:10.1136/bmj.f4841.

56. Pradhan N, Desai S, Kagal A, Dharmashale S, Bharadwaj R, Ghorpade S, Gaikwad S, Kulkarni V, Gupte N, Bollinger RC , Gupta A, Mave V. Patterns of TB drug-resistance in a tertiary care facility in Pune, India. Clin Microbiol 2013; 2:123. doi: 10.4172/2327-5073.100012

57. Jain SK, Ordonez A, Kinikar A, Gupte N, Thakar M, Mave V, Jubulis J, Dharamshale S, Desai S, Hatolkar

S, Kagal A, Lalvani A, Gupta A, Bharadwaj R. Pediatric tuberculosis in young children in India: a prospective study. BioMed Res Int Vol. 2013, Article ID 783698, doi:10.1155/2013/783698. PMCID: PMC3872373

58. Mave V, Suryavanshi N, Kulkarni V, Balasubramanian U, Jadhav A, Bhattacharya D, Patil S, Khandekar

M, Paranjape R, Tripathy S, Kinikar A, Bharadwaj R, Bhosale RA, Sambarey P, Jamkar A, Sastry J, Bollinger RC, Gupta A for the SWEN India Study team. Impact of maternal hepatitis B virus coinfection on mother-to-child transmission of HIV. HIV Med 2014; doi: 10.1111/hiv.12120.

59. Jubulis J, Kinikar A, Ithape M, Khandave M, Dixit S, Hotalkar S, Kulkarni V, Mave V, Gupte N, Kagal A,

Jain S, Bharadwaj R, Gupta A. Modifiable risk factors associated with tuberculosis disease in children in Pune, India. Int J Tuberc Lung Dis 2014, 18(2):198-204; doi: 10.5588/ijtld.13.0314

60. Gupta A, Mathad JS, Yang W-T, Singh HK, Gupte N, Mave V, Bharadwaj R, Zaman K, Roy E, Bollinger

RC, Bhosale R, Steinhoff MC, for the SWEN India Study Team. Maternal pneumococcal capsular IgG antibodies and transplacental transfer are lower in South Asian HIV-infected mother-infant pairs. Vaccine 2014; 32(13):1466-72. PMCID:PMC3975143

61. Nelson GE, Mave V, Gupta A. Biomarkers for sepsis: a review with special attention to India. BioMed

Res International 2014, http://dx.doi.org/10.1155/2014/264351.

62. Havers FP, Detrick B, Cardoso SW, Berendes S, Lama JR, Sugandhavesa P, Mwelase NH, Campbell TB, Gupta A. Change in Vitamin D levels occurs early after antiretroviral therapy initiation and depends on treatment regimen in resource-limited settings. PLoS ONE, April 21, 2014, doi:10.1371/journal.pone.0095164. PMC in process

Page 8

63. Mathad JS, Bhosale R, Sangar V, Mave V, Gupte N, Kanade S, Nangude A, Chopade K, Suryavanshi N,

Deshpande P, Kulkarni V, Glesby MJ, Bharadwaj R, Sambarey P, Gupta A. Pregnancy differentially impacts performance of latent tuberculosis diagnostics in a high-burden setting. PLoS ONE 2014; 9(3):e92308. PMCID:PMC3962385

64. Yang W-T, Gounder CR, AkandeT, De Neve J-W, McIntire K, Chandrasekhar A, de Lima Pereira A,

Gummadi N, Samanta S, Gupta A. Barriers and delays in tuberculosis diagnosis and treatment services: does gender matter. Tuberc Res Treat 2014; Vol 2014, Article ID 461935, doi:10.1155/2014/461935.

65. Krishnan L, Akande T, Shankar A, McIntire K, Gounder CR, Gupta A, Yang W-T. Gender-related barriers and delays in accessing tuberculosis diagnostic and treatment services - Part 2: a systematic review of qualitative studies. Tuberc Res Treat 2014; Vol. 2014, Article ID 215059, doi:10.1155/2014/215059.

66. Havers F, Smeaton L, Gupta N, Detrick B, Bollinger R, Hakim J, Kumarasamy N, Andrade A, Christian P,

Lama J, Campbell TB, Gupta A. 25-hydroxyvitamin D insufficiency and deficiency is associated with HIV disease progression and virological failure post-antiretroviral therapy initiation in diverse multinational settings. J Infect Dis 2014; doi: 10.1093/infdis/jiu259. PMC in process

67. Suryavanshi N, Raval G, Kanade S, Nimkar S, Nadgiri V, Sahu P, Kadam D, Khadse S, Mave V, Gupte N, Gupta A. Challenges to disclosure of HIV status to perinatally infected children: a study of caregiver perspectives in Pune, India. Int J Ped Infect Dis (Accepted June 2013)

68. Suryavanshi N, Mave V, Gupte N, Bhosale R, Sambarey P, Patil S, Sastry G, Bollinger R, Gupta A,

Shankar A. Contraceptive use and factors associated with postpartum surgical sterilization among HIV-infected women in Pune, India. J HIV/AIDS Soc Serv (Accepted September 2013)

69. Sastry J, Deshmukh V, Dhoiphode V, Wele A, Solanki M, Rizwan F, Gupta K, Kentoffio K, Sibi S,

Karandikar N, Gupta A, Shankar A. The teaching of HIV and AIDS by traditional Indian systems of medicine: faculty perspectives. J Homeop Ayurv Med (Accepted October 2013)

70. Gupte N, Kinikar A, McIntire KN, Bhosale R, Patil S, Suryavanshi N, Mave V, Kulkarni V, Bollinger RC, Gupta A for the India SWEN and BJMC-JHU Study Group. Efficacy of six-week extended-dose nevirapine varies by infant birth weight with greatest relative efficacy in low birth weight infants. J Ped Infect Dis Soc (Submitted June 2014).

71. Shivakoti R, Gupte N, Yang W-T, Mwelase N, Kanyama C, Tang A, Pillay S, Samaneka W, Riviere C, Berendes S, Lama JR, Cardoso SW, Sugandhavesa P, Semba RD, Gupta A. Pre-antiretroviral therapy selenium status predicts WHO stages 3, 4 or death but not virologic failure post-antiretroviral therapy. JAIDS (Submitted July 2014)

72. Shivakoti R, Christian P, Yang W-T, Gupte N, Mwelase N, Kanyama C, Pillay S, Samaneka W, Santos B,

Poongulali S, Tripathy S, Riviere C, Berendes S, Lama JR, Cardoso SW, Sugandhavesa P, Tang A, Semba RD, Campbell TB, Gupta A for the NWCS 319 and PEARLS study team. Prevalence and risk factors of micronutrient deficiencies pre- and post-antiretroviral therapy (ART) among a diverse multicountry cohort of HIV-infected adults. (Currently under ACTG review before submission to American Journal of Clinical Nutrition.

73. Balagopal A, Asmuth DM, Yang W-T, Campbell T, Gupte N, Smeaton L, Kanyama C, Grinsztejn B,

Santos B, Supparatpinyo K, Badal-Faesen S, Lama JR, Lalloo U, Zulu F, Pawar JS, Riviere C, Kumarasamy N, Hakim J, Li X-D, Pollard RB, Semba RD, Thomas DL, Bollinger RC, Gupta A. Pre-HAART elevation of CRP and CD4+ T-cell immune activation associated with HIV clinical progression in a multinational case-cohort study. (To be submitted to JID)

Page 9

74. Tenforde M, Gupte N, Dowdy D, Asmuth DM, Balagopal A, Pollard RB, Sugandhavesa P, Lama JR,

Pillay S, Cardoso SW, Pawar J, Santos B, Riviere C, Mwelase N, Kanyama C, Kumwenda J, Hakim JG, Kumarasamy N, Bollinger R, Semba RD, Campbell TB, Gupta A for the ACTG PEARLS and NWCS 319 Study Group. Baseline inflammatory and immune activation markers predict tuberculosis after initiation of antiretroviral therapy in resource-limited settings. J Acquir Immune Defic Syndr (Submitted May 2014)

75. Gupta Nikhil, Gupta A, et al. Efficacy of six-week extended-dose nevirapine varies by infant birth weight

with greatest relative efficacy in low birth weight infants. J Ped Infect Dis Soc (Submitted June 2014)

Inventions, Patents, Copyrights: N/A Extramural Funding Current Grants 04/16/09-3/31/15 Impact of Nutritional Status on Early HIV Treatment Failure in Resource-Limited Settings R01 AI 080417

National Institutes of Health, NIAID $2,299,783 Role: Principal Investigator, 17%

04/01/10-03/31/15 Indo-US Global Health Education and Research Trainees Capacity Building Gilead Foundation $120,000 Role: Principal Investigator, 1% 11/01/12-01/31/18 The Impact of Diabetes on TB Treatment Outcomes

R01AI1096494 National Institutes of Health $446,558 PI: Jonathan Golub Role: Co-Investigator, 11%

01/01/13-12/31/15 Indo-US Clinical Education and Research Capacity Building Ujala Foundation

$200,000 Role: Principal Investigator, 1% 09/01/13-08/31/18 c-TRIUMPh: Cohort for TB Research by the Indo-US Medical Partnership

U.S. Civilian Research and Development Foundation $179,271 Role: Principal Investigator, 19% 09/02/13-09/01/15 COMmunity Home Based INDIA Prevention of Mother-to-Child Transmission

(COMBIND PMTCT) Study Centers for Disease Control and Prevention U01GH000731 CDC

$103,645 PI: Nishi Suryavanshi Role: Co-Investigator, 4% Page 10

12/10/13-12/09/20 BWI Clinical Trials Unit for NIAID Networks National Institutes of Health, NIAID $1,777,018 Role: Co-Principal Investigator, 35%

01/01/14-11/30/14 International Maternal Pediatric Adolescent AIDS Clinical Trials Group (IMPAACT) National Institutes of Health, NIAID UM1AI068632-08 $14,380 PI: Sharon Nachman Role: TB Scientific Committee Vice Chair, 9.16%

01/01/14-11/30/14 AIDS Clinical Trial Group (ACTG) A5274/REMEMBER: Reducing early mortality and early morbidity by empiric tuberculosis treatment regimens and, A5279: A multicenter, randomized, open-label, phase III clinical trial comparing a 4-week daily rifapentine (RPT)/isoniazid (INH) regimen to a standard 9-month daily INH regimen for the prevention of tuberculosis (TB) in HIV-infected participants without evidence of active TB) National Institutes of Health, NIAID 7UM1AI068636-07 $22,236 PI: Daniel Kuritzkes Role: Protocol Vice Chair, 6.4%

01/27/14-01/31/15 Mylan, Inc.

Collaborative Agreement Mylan Pharmaceutical $9,150 Role: Principal Investigator 1%

01/01/14-06/30/14 amFAR, The Foundation for AIDS Research Epidmiology of HIV/AIDS and associated comorbidities in a public antiretroviral

treatment (ART) clinic in Pune, India $21,000 Role: Principal Investigator 1%

Pending Grants 05/01/14-04/30/19 Innovative PK/PD Approaches to Optimize TBM Treatment in Children (PATCH Study) National Institutes of Health, NICHD $515,499 PI: Kelly Dooley Role: Co-Investigator, 10% 07/01/14-06/30/18 Impact of Immune Changes of Pregnancy on Tuberculosis

National Institutes of Health, NICHD $1,769,933 Role: Principal Investigator, 10%

07/01/14-06/30/18 Indoor Air Pollution, Immune Function, and Pediatric TB in India

National Institutes of Health, NICHD $1,861,597 Role: Principal Investigator, 10%

Page 11

01/01/15-12/31/19 Evaluate the Innate Immune Responses of Household Contacts of TB Patients

National Institutes of Health, NIAID $92,550 PI: Ramakrishna Vankayalapati Role: Co-Investigator, 5%

Previous Grants 9/1/99-1/31/08 Prevention of Maternal to Infant HIV Transmission in India

U01-AI045462 National Institutes of Health

$5,447,119 PI: Robert Bollinger Role: Co-Investigator, 15%

7/01/00-1/31/09 HIV Prevention Trial Unit (HPTU) – Pune, India U01 AI47968 National Institutes of Health, NIAID $8,515,370

PI: Robert Bollinger Role: Co-Investigator, 25%

7/16/05-7/1/08 K12 Junior Faculty Award K12RR017627

NIH-Johns Hopkins University $300,000 Role: Principal Investigator, 90% in Yrs 1-2; 25% in Yr 3

4/5/06-4/4/07 Independent Evaluation of NACP II

100003 National AIDS Control Organization $70,618 PI: Shruti Mehta Role: Co-Investigator, 5%

7/1/08-4/15/09 Clinician Scientist Award Johns Hopkins University

$76,625 Role: Principal Investigator, 53%

8/15/07-1/31/14 National AIDS Research Institute, Pune, India: Clinical Trials Unit

U01 AI069417 National Institutes of Health, NIAID $80,026

PI: Sanjay Mehendale Role: Co-Investigator, 10%

7/1/07-6/30/10 Examination of the Role of Traditional Indian Medicine for HIV/AIDS in India 1EA 0000057

Samueli Institute for Information Biology $40,235 (no cost extension pending) Role: Principal Investigator, 8%

Page 12

9/15/09-03/31/13 Diagnosis of Active TB in HIV-Infected and Uninfected Young Children in India R03 HD061059

National Institutes of Health, NICHD $100,000

PI: Sanjay Jain Role: Co-Principal Investigator, 1%

06/01/11-05/31/12 Social and Scientific Systems – Task Order BRS-IMPCT-S-11-00001-001675 $4,956 Role: Principal Investigator 3%

05/02/12-04/30/13 CFAR Development Core Mentoring Award $5,000 Role: Mentor to Vidya Mave, M.D. for CFAR Faculty Award, 2%

4/1/06-11/30/13 Johns Hopkins AIDS Clinical Trial Unit U01 AI069465

National Institutes of Health, NIAID $6,446,398

PI: Charles Flexner Role: Co-Investigator, 5%

09/20/07-1/31/14 Byramjee Jeejeebhoy Medical College (BJMC), Pune India: Clinical Trials Unit U01 AI069497 National Institutes of Health, NIAID $6,748,829 Role: Principal Investigator, 19%

Previous Contracts 10/1/08-9/30/09 Association of Transplacental Pneumococcal, Influenza, and Tetanus Antibodies 104404 Children’s Hospital Medical Center – Cincinnati (Gates Foundation) $180,000 PI: Mark Steinhoff Role: Co-Investigator, 7% Research Program Building/Leadership 2007-present Byramjee Jeejeebhoy Medical College (BJMC) Clinical Trials Unit Pune, India Research capacity building ongoing mentorship of junior and mid-level India based clinical researchers. Mentor several US university students’ research experiences in India. EDUCATIONAL ACTIVITIES Educational Publications Case Reports

1. Gupta A, Khedhar S. Images in clinical medicine. Eye worm. N Engl J Med. 2005; 353(25):e22. Page 13

2. Karakousis P, Sylvester S, Gupta A. Paraplegia caused by invasive spinal aspergillosis. Neurology

2007; 68(2):158

3. Sheth A, Devgan L, Gupta A, Bollinger RC. A traveling farm wife. Am J Med. 2007; 120(1):16-8

4. Bowman NM, Falade O, Gupta A. An unexpected source. Am J Med. 2010; 123(11):993-5.

5. Sharma YK, Virmani NC, Dash KN, Deo KS, Mave V, Gupta A, Kakrani A. Photo Quiz. A 23-year-old man presenting with fluid-filled skin lesions, patchy pigmentation, and skin breakage after trivial trauma. Clin Infect Dis 2013; 56:851-59.

Letters, Correspondence

1. Gupta A, Tauxe RV, Angulo FJ. Authors’ response to Peter Collignon’s EID article. Emerg Infect Dis 2005; 11 (11);1791-92.

2. Gupta A, Bhosale R, Sambarey P, Patil S, Gupte N, Bollinger RC, for the BJ Medical College-Johns Hopkins University Study Group. Authors’ response to Hanrahan et al CID article. Clin Infect Dis 2012 May; 54(9):1378-79. Epub 2012 Mar 14.

Book Chapters/Monographs

1. Gupta A and Green B. Women and Access to Care. In: Searching for Women: A Literature Review on Women and HIV Disease in the United States, University of Massachusetts Press. Boston, 1992.

2. Contributing author to 2002 and 2006 Red Book of the American Academy of Pediatrics. Clostridium Perfringens and Shigella chapters. In Pickering LK, ed. 2002/2006 Red Book: Report of the Committee on Infectious Diseases. 26 and 27th ed. Elk Grove Village, IL. 2003/2006.

3. Gupta A and Bollinger RC. Treatment of Intestinal Parasites. In: Advanced Therapy of Gastrointestinal Diseases 5th Edition. Bayless TM and Diehl AM, Editors. BC Decker, Inc, Hamilton, Ontario, Canada, 2005.

4. Gupta A, Hirschhorn LR, Piliero PJ and Gallant JE. Diagnostic Approach to Common Clinical Syndromes. In: HIV 3rd edition. Libman H and Makadon H, Editors. American College of Physicians. Philadelphia, 2007.

5. Gupta A, Bollinger RC. Combating HIV/AIDS: The Need for Public-Private Health Partnerships, In:

Global Scenario on HIV and AIDS: Is There a Way Out? Naveen Kumar and VV Ramani, Editors. Icfai University Press, Hyderabad, India 2008.

6. Westergaard R, Gupta A. Management of the Patient with HIV Disease. Conn’s Current Therapy 2010 Bope ET, Rakel RD, Kellerman R, Editors. Elsevier Inc. (also updated for 2011 edition).

7. Auwaerter P, Bartlett J, Berkenblit G, Blankson J, Brown T,Cofrancesco J, Dunn J, Ghanem, K,

Gupta A, Harrison D, Hoffman C, Hsu J, Kouba D, Lechtzin N, Levy M, Marinopoulos S, McKenzie R, Melia M, Moore R, Neofytos D, Newsome S, Nuermberger E, Page K, Ratchford J, Rumbaugh J, Sindwani R, Sosnay P, Spacek L, Sterling T, Treisman G, Wagner-Johnston N, Wilgus B, Vinetz J. HIV Guide Titles 2011.

Other Media (films, videos, CD-ROMS, slide sets, etc)

1. Johns Hopkins HIV Poc-IT Guide Page 14

Author of 8 online HIV clinical management modules since 2006 on Blastomycoses, Coccidiomycosis, Cryptococcal disease, Esophageal candidiasis, Histoplasmosis, Oral candidiasis, Post-exposure prophylaxis, Salmonella.

2. Center for Clinical Global Health Education online web courses: content developer for slide sets on HIV

care and treatment course in India 2005-present.

3. HIV Guide Question and Answer Faculty. Answer questions related to HIV-opportunistic infections.

4. Monthly India case discussion with National AIDS Research Institute and BJ Medical College, Pune, India.

5. Center for Clinical Global Health Education online web courses: TB and PMTCT courses instructor, 2009.

Teaching

Clinical Instruction

2002-present Moore Clinic: Attending physician supervision/training of medical students, residents, post-doctoral fellows in the outpatient HIV clinic.

2006-present Frank Polk Unit Service: Attending physician supervision/training, daily teaching

rounds for medical students, residents, post-doctoral fellows in the in-patient HIV unit at Johns Hopkins Hospital

2006-present Infectious Diseases Consultation Service: Attending physician

supervision/training, daily teaching rounds for medical students, residents, post-doctoral fellows with the in-patient infectious diseases consultation service at Johns Hopkins Hospital

CME Instruction

March 14, 2006 Johns Hopkins HIV Clinical Care Conference Baltimore, Maryland

Lecture: “Old Dog, New Tricks: An Update in Opportunistic Infections”

May 21, 2007 Johns Hopkins HIV Clinical Care Conference Baltimore, Maryland

Lecture: “An Update in Opportunistic Infections” May 18, 2008 Johns Hopkins HIV Clinical Care Conference

Baltimore, Maryland Lecture: “An Update in Opportunistic Infections”

January 8, 2008 Medscape Infectious Diseases C. difficile Update: Literature Commentary, with John Bartlett

October 18, 2008 Christiana Hospitals

Wilmington, Delaware Lecture: “An Update in Opportunistic Infections”

May 5, 2009 Johns Hopkins School of Medicine Johns Hopkins HIV Clinical Care Conference Baltimore, Maryland HIV Case Discussion

Page 15

August 3, 2009 Medical Logix

IAS 2009 Conference Highlights. Management of HIV Treatment Highlights Baltimore, Maryland. Webcast for online CME

Mentoring Advisees 2003-2005 Ramona Farid, M.D., Post-doctoral Fellow, Johns Hopkins University School of Medicine, Infectious Diseases, Sinai Hospital, Baltimore, MD. Assisted her in study design and a publication on HIV inpatient mortality in India. 2004-2006 Suneil Ramachandani, M.D. White House Fellow. Mentor for project and publication on HIV care

practices in India. 2003-2004 & Shuchi Anand, M.D., Resident, Brigham & Women’s Hospital, Boston MA. Assisted her on 2006-2007 project and publication of post exposure prophylaxis among health care workers in India. 2005-2007 Bijal Shah, M.D., Resident, Emergency Medicine, University of North Carolina. Mentor for project on HIV treatment in Mumbai resulting in 3 papers. 2006-present Harjot Singh, M.D., New York-Presbyterian Hospital/Weill Cornell Medical Center,

New York, NY. Mentored her during her ID fellowship at JHU in 3 publications related to morbidity in HIV-infected women and children.

2008-present Nick Arora, B.S., Undergraduate, Public Health Major, Johns Hopkins University. Assisted him to be a recipient of Merck Scholarship Award for TB/HIV project in Kakinada, India, which has resulted in a publication. 2009-present Karthik Rao, B.S., Undergraduate, Public Health Major, Johns Hopkins University. Recipient

of Woodrow Wilson Scholarship and assisted him to win the Bander Family Fund Award to conduct a study to assess impact of HIV and smoking in Stellenbosch, South Africa. Mentor for undergraduate thesis.

2009-present Debalina De, B.S., Undergraduate, Public Health Studies, Johns Hopkins University. Assisted her to win the Fulbright award for India to explore health care for children with tuberculosis.

2009-present Nivedita Mohari, M.D. Pediatric resident at Sinai Hospital, Baltimore. Research mentor on impact

of material anemia of infant anemia and outcomes. Helped her win best research project for a pediatric resident.

2009-2011 Naveen Gummadi, M.D. Assisted him in clinical and research clerkship focused on TB in women

systematic review and with an International AIDS Society (IAS) 2010 poster and publication on a systematic review of early mortality in HIV.

2009-present Nikhil Gupte, PhD, BJ CTU, Deputy Director and Data Manager, Pune, India. Junior faculty

mentor for TB/HIV manuscripts and analyses. 2009-2012 Jennifer Jubulis, M.D., Pediatric ID Fellow, Johns Hopkins University. Mentor for project focused

on pediatric TB, malnutrition, and immune-based TB diagnostics in India. October 2012, Faculty, Pediatric Infectious Diseases, University of Maine

2009-present Jyoti Mathad, M.D., Adult ID Fellow, Cornell University. Mentor for project on latent TB

detection in pregnancy in India, resulting in 5 abstracts and 3 publications. Infectious Diseases Page 16

Society of America (IDSA) Fellows Award recipient. KL2 co-mentor. 2009-present Sushant Sahastrabeddhe, M.D., M.P.H. candidate. M.P.H. Capstone Advisor. Study of HIV and

STI risk among hijrahs in India. 2010-present Vidya Mave, M.D., BJ CTU, Clinical Research Site Leader, Pune, India. Provide mentorship for

HIV/TB grants and manuscripts. 2010-present Jonathan Dyal, JHU medical student, Doris Duke Fellowship Awardee; Dean’s Award and Scholarly

Concentration project to do crypotococcal meningitis retrospective review at BJMC, India. 2010-present Benjamin Keleman, JHU medical student, Dean’s Award and Scholarly Concentration project to

do a pediatric TB retrospective review at BJMC, India. 2010-present Naomi Garland, Tufts University School of Medicine, perform an assessment to current status and barriers to optimal integration of TB/HIV services for women, BJMC, India. 2011-2013 Bhavesh Modi, M.P.H. Capstone Advisor (2011-12), Academic Advisor (2012-13) Evaluation of

tobacco cessation intervention for tuberculosis patients under revised National Tuberculosis Control Programme in Rural and Urban areas at Vadodara, Gujarat, INDIA

2011-present Gauri Raval, M.P.H. Capstone Advisor. Challenges to Disclosure of HIV Status to Perinatally

Infected Children: A Study of Caregiver Perspectives in Pune, India 2011-2012 Fiona Havers, M.D. Research mentor for Vitamin D and HIV studies in resource limited settings.

Conference on Retroviruses and Opportunistic Infections (CROI) Young Investigator Award. July 2012, Centers for Disease Control, Epidemic Intelligence Service officer in Flu Branch

2012-present Mark Tenforde, M.D. Research mentor for TB and malnutrition. Received the Center for Global

Health Resident Global Health Travel Grant. Conference on Retroviruses and Opportunistic Infections (CROI) Young Investigator Award 2014. Recipient of the Afya Bora Fellowship 2014.

2012-2013 Nikhilesh Ray-Mazumder, M.P.H., Academic Advisor. Received Dean’s award to travel to Pune,

India to work on antibiotic resistance in patients in the emergency room at the BJ Medical College/Sassoon General Hospital.

2013-present Akshay Gupte, M.D, M.P.H.S., Ph.D. candidate. PhD advisor for project focused on epidemiology

of potentially modifiable risk factors for TB in India. 2013-present Ashish Yadav, M.P.H. candidate. Capstone Advisor. Effect of micronutrient status on incident

tuberculosis among HIV infected patients receiving anti-retroviral therapy in resource limited settings.

2013-present Jayalakshmi Bhat, M.P.H. candidate. Academic Advisor, Capstone Advisor. Increased risk of

perinatal HIV transmission among mothers with HIV and syphilis co-infection. 2013-present Erin Ewald, M.P.H. Candidate. The impact of nutritional and inflammatory biomarkers on

CD4 recovery in an HIV-positive, treatment-naive cohort. 2014-present Samuel Holzman, M.D., Internal Medicine Fellow, Johns Hopkins University. Mentor for the

MDR TB database at Hinduja Hospital in Mumbai, Inida. Recipient of Housestaff Global Health Travel Grant funded by Johns Hopkins Medicine and the Center for Global Health.

Page 17

Thesis Committees 2007-2008 Ajay Gurbani, B.S., Undergraduate, Public Health Major, Johns Hopkins University.

Recipient of Woodrow Wilson Scholarship. Public Health Thesis Advisor (HIV knowledge, attitudes and practices among Pune-based community pharmacies)

2008-2009 Katherine Kentoffio, B.S., Undergraduate senior, Public Health Studies, Kreiger School of Arts and Sciences, "Understandings of HIV/AIDS Among Faculty Members of Traditional Indian Medicine and Homeopathy in Pune, India"

2009-2010 Adrienne Shapiro, PhD, Thesis Committee, Johns Hopkins Bloomberg School of Public Health. Evaluating an Active Case Finding Strategy for TB and HIV in South Africa. 2013-present Cesar Ugarte, PhD, Thesis Committee, Johns Hopkins Bloomberg School of Public Health.

“Tuberculosis and Diabetes in Peru” 2012-present Jessica Elf, M.P.H., Recipient of Fogarty Award, Fogarty Global Health Fellows Training

Program. Co-advisor for project “Assessing the association of indoor air pollution with TB in adult women and children.

Training Grant Participation

National Institutes of Health Title: Research Training in Microbial Diseases 09/01/11-08/31/16 T32AI007291 Principal Investigator: Kelly Gebo Role: Mentor (Training grant, 0% effort, 0% salary support) National Institutes of Health Title: HIV-TB Fogarty Research Training Program 08/09/13-01/31/18 1D43TW009574-01 Principal Investigator: Robert Bollinger Role: Mentor (Training grant, 3% effort, 3% salary support)

Educational Program Building / Leadership 2005-present Deputy Director of Center for Clinical Global Health Education, mission of which is to train

healthcare workers in low-income countries evidence-based clinical prevention and management of infectious diseases

Educational Extramural Funding Current 2005-present Center for Clinical Global Health Education (CCGHE)

Helped to fundraise $250,000 from private donations to date Previous 2007 CME grants to support Infectious Diseases Grand Rounds from

Pfizer $80,000 Tibotec $5,000 Boehringer-Ingelheim $60,000

Page 18

CLINICAL ACTIVITIES Certification

Medical, other state/government licensure 1997-2006 California State Medical License A068481

2003-present Maryland State Medical License D0059333

Boards, other specialty certification 2000 Board Certified, American Board of Internal Medicine 2005 Board Certified, Infectious Diseases Clinical (Service) Responsibilities 2007-present Moore Clinic: HIV primary care provider, outpatient continuity care, HIV primary care,

one afternoon/week 2002-2008 Moore Clinic: Attending physician, supervision/training of medical students, residents,

post-doctoral fellows in the outpatient HIV clinic, one afternoon/week 2005-present Infectious Diseases Consultation Service: Attending physician, supervision/training,

daily teaching rounds for medical students, residents, post-doctoral fellows, 2-3 weeks/year

2005-present Frank Polk Unit: Attending physician, supervision/training, daily teaching rounds for

medical students, residents, post-doctoral fellows in the in-patient HIV unit, 2-3weeks/year

Clinical Program Building/Leadership N/A Clinical Extramural Funding N/A SYSTEM INNOVATION AND QUALITY IMPROVEMENT ACTIVITIES N/A ORGANIZATIONAL ACTIVITIES Institutional Administrative Appointments 2004-present Deputy Director, Center for Clinical Global Health Education The Johns Hopkins Department of Medicine

2007-present Member, Infectious Diseases Fellowship Interviewing Committee

2009-present Member, Infectious Diseases Fellowship Curriculum Committee

2009-present Member, Infectious Diseases Fellowship Recruitment and Selection Committee

2009-present Member, General Internal Medicine Fellowship Interviewer

2011-present Member, Johns Hopkins School of Medicine Women’s Task Force

Page 19

Editorial Activities

Journal Reviewer

2011-present Journal of Obstetrics and Gynaecology Research

2010-present British Medical Journal

2010-present Journal of Infectious Diseases

2010-present BMC Public Health

2009-present BMC Infectious Diseases

2009-present Epidemiologic Reviews

2009-present Canadian Medical Association Journal

2008-present American Academy of HIV Medicine

2007-present Clinical Infectious Diseases

2007-present Drug Discovery Today

2006-present JAIDS

2006-present Pediatric Infectious Diseases Journal

2005-present Emerging Infectious Diseases

2005-present AIDS Patient Care and STDs

2005-present Journal of Clinical Microbiology

2004-present American Journal of Tropical Medicine and Hygiene

2002-present WHO Bulletin

2011-present Journal of Obstetrics and Gynaecology Research

2012-present PLoS One

2014- Lancet

2014- The International Journal of Tuberculosis and Lung Disease

Advisory Committees, Review Groups/Study Sections 2005-2012 Member, Clinical Management Committee (CMC), HIV Prevention Trials Network Study

HPTN 052, A Randomized Trial to Evaluate the Effectiveness of ART plus HIV Primary Care versus HIV Primary Care Alone to Prevent the Sexual Transmission of HIV-1 in Serodiscordant Couples

2006 CFAR Johns Hopkins Pilot Grants Reviewer 2007 Canadian Institutes of Health Research (CIHR) grant reviewer 2007 AMFAR Grant Reviewer 2007-2011 Elected Member, ACTG Optimization of Co-Infection and Co-Morbidity Management

(OPMAN) Committee 2007-2010 Elected Member, ACTG Optimization of Co-Infection and Co-Morbidity Management

(OPMAN) IRIS Working Group

Page 20

2008-2009 Elected Member, ACTG Optimization of Antiretroviral Therapy (OPART) Second Line Drugs Working Group

2008-2010 Elected Member, ACTG Mortality Focus Group of the Optimization of Antiretroviral

Therapy (OPART) 2008 NIH NICHD Study Section Invited RO1 Grant Reviewer

ZHD1 DSR-K (07) 1- Diagnostic and pharmacokinetic research in pediatric HIV/TB and effects of co-infection on the central nervous system 2008 Johns Hopkins Center for Global Health faculty grants reviewer

2009 Invited Member, NIH/NICHD Nutritional Care of HIV infected Adolescents and

Adults (including pregnant and lactating women) Working Group 2010 Johns Hopkins University Center for Global Health Faculty grants reviewer 2011-present Member, Clinical Management Committee (CMC), IMPAACT PROMISE P1077,

Promoting Maternal and Infant Survival Everywhere 2011-2013 Member, WHISC TB Women’s Working Group 2011-2013 Elected Member, ACTG TB Transformative Science Group (TSG) 2011 NIH/NIAID, Special Emphasis Panel

NIH/PEPFAR Collaboration for Implementation Science and Impact Evaluation 2012-present Vice-Chair Elect of IMPAACT TB Scientific Committee 2012 Abstract Reviewer, 2012 43rd Union World Conference on Lung Health 2013 NIH Working Group Chair for advancing the involvement of pregnant women earlier into TB

drug trials 2014-2016 US Co-Chair RePORT India Executive Committee 2014 Invited Member, NIH DAIDS Working Group on TB drug trials in children and

pregnant/lactating women 2014 Abstract Reviewer, 2nd GETHealth Summit (Global Education and Technology) Professional Societies 1997-2006 Member, American Medical Association

2001-present Member, Infectious Disease Society of America

2001-2003 Member, American Society of Tropical Medicine and Hygiene

2006-present Member, International AIDS Society

2008-present Member, AAHIVM

2014 Member, International Union Against Tuberculosis and Lung Disease

Conference Organizer, Session Chair 2006 Samueli Institute and Indian Council of Medical Research. Scientific Coordinator for

“Traditional Indian Medicine for HIV/AIDS: A Research Agenda” Conference New Delhi, India

Page 21

2007, 2009, 2011 HHRF, Mumbai, India. Scientific Coordinator for “HIV Treatment in India” National Conference, Mumbai, India. Coordinated scientific agenda and invitation of 50 speakers in collaboration with HHRF, Mumbai, India

July 29, 2010 NIH Forum to Promote TB Research in Underserved Maternal and Pediatric Populations

with HIV. Invited Session Chair: Drug development for XDR/MDR TB for women and children

Consultantships 2002 U.S. Centers for Disease Control and Prevention

Consultant on food borne pathogens and drug resistance in the United States

2006 Samueli Institute for Information Biology Consultant on traditional Indian medicine and HIV

2006-2007 Indian Ministry of Family Health and Welfare, National AIDS Control Organization,

Consultant on national surveillance for HIV in India 2010-2011 Consultant on systematic review of TB in women, World Health Organization. RECOGNITION

Awards, Honors

1991 MIT Women Studies Writing Prize “Women and AIDS in the United States: Unheard Voices”

1991 MIT Student Humanitarian Award

1991 Sigma Xi Research Honor Society

1993 Harvard Medical School Urban Health Fellowship

1996 Paul Dudley White & Andrew Sellard Traveling Fellowship

2000 IDSA Special Citation for Fellows-in-Training

2001 Reza Gandeji Award (UCSF resident award for medical ethics and compassionate patient care)

2002 Mackel Finalist, Epidemic Intelligence Service Conference, Centers for Disease Control and

Prevention

2002 U.S. Public Health Service Award for Bioterrorism Surveillance Post 9/11

2002 U.S. Public Health Service Award for Foreign Duty Service (cholera in Micronesia)

2007 Clinician Scientist Award, Johns Hopkins University School of Medicine

Invited Talks/Panels (last 3 years)

January 10, 2010 National HIV CART Conference

Chennai, India Lecture: "Early Mortality post HAART initiation in low- and middle-income countries"

January 13, 2010 BJMC Medical Grand Rounds

Pune, India Lecture: "Early mortality post HAART initiation in low- and middle-income countries"

Page 22

January 18, 2010 National AIDS Research Institute

Symposium on Policy, Program and Care for HIV/AIDS in India Pune, India Lecture: "Beyond current first-line antiretrovirals: need for second-line and newer drugs as well as

optimized care” January 22, 2010 National AIDS Research Institute

Pune, India Lecture: "Early mortality post HAART initiation in low- and middle-income countries"

May 26, 2010 Johns Hopkins University School of Medicine

TB Clinical and Epidemiology Noon Conference Baltimore, MD Lecture: “TB/HIV in women and children: research in India and beyond”

June 11, 2010 Johns Hopkins University Center for Tuberculosis Research

Annual Scientific Meeting Baltimore, MD Lecture: “Is TB a risk factor for mother-to-child transmission of HIV?”

June 24, 2010 Foreign Service Institute, US State Department

Arlington, VA Lecture: “South Asia health issues”

July 27, 2010 NIH

Nutrition in Clinical Management of HIV Infected Adolescents (>14 yr) and Adults including Pregnant and Lactating Women: What do we know, what can we do, and where do we go from here? Symposium Lecture: “Nutrition and disease progression Pre- and Post-ART: can good nutrition delay

time to and response to ART?”

July 29-30, 2010 IH Forum to promote TRIUMPH (TB Research in Underserved Maternal and Pediatric Populations

with HIV) Chair: “Scope of the Problem: Epidemiology of co-infection, as it relates to women, especially

pregnant women, and children with HIV and TB” Discussant. “Biomarkers and Diagnostics for women: Influence of pregnancy” Round Table Member: Reaction to Day 1: priorities, synthesis, feedback

September 30, 2010 ICOPA Conference

New Delhi, India Lecture: “TB in HIV-Infected pregnant women”

November 13, 2010 41st Union World Conference on Lung Health

Berlin, Germany Symposium Lecture: “Aspects of congenital/neonatal TB and detection of TB in pregnancy in HIV

infected/uninfected women”

Page 23

January 6, 2011 MCHIP, JHPIEGO

Washington DC Lecture: “Tuberculosis in pregnancy: Impact on maternal and child health”

July 13, 2011 High Risk Obstetrical Conference

Johns Hopkins University School of Medicine Baltimore, MD Lecture: “TB in pregnancy”

October 26, 2011 42nd Union World Conference on Lung Health

Stop TB symposium "Meeting the unmet needs of women and children for TB prevention, diagnosis and care: expanding our horizons" Lille, France Lecture: “Diagnosis and treatment of TB in HIV positive women”

January 5, 2012 University of Pennsylvania School of Medicine

Philadelphia, PA Infectious Diseases Grand Rounds Lecture: “TB in pregnant women “

January 12, 2012 Dr. Y Patil Vidyapeeth, Pune Deemed University

Pune, India Medical Grand Grounds Lecture: “TB in women”

March 8, 2012 CROI 2012

Seattle, WA Moderator: “TB and vaccine preventable diseases”

April 13, 2012 Brazil-Hopkins AIDS Conference

Rio de Janeiro, Brazil Lecture: “Update in TB and IRIS”

July 31, 2012 Johns Hopkins School of Medicine

Baltimore, MD Medical and Educational Perspectives-Medical Design Initiative Seminar Lecture: “Hospitals and Health Care in India”

December 2012 Johns Hopkins Bloomberg School of Public Health

Graduate Training Program in Clinical Research (GTCPI) Lecture: “Conducting International Research”

Page 24

January 2013 Human Healthcare and Research Foundation

4th National Conference on HIV/AIDS Therapy Mumbai, India Lecture: “Update in TB Diagnosis, Treatment and Prevention”

April 19, 2013 Brazil-Hopkins AIDS Conference

Rio de Janeiro, Brazil Lecture: “Update in TB Diagnosis, Treatment and Prevention”

May 16, 2013 Johns Hopkins Center for TB Research Seminar

Baltimore, MD Lecture: “TB in Pregnant and Postpartum Women”

May 22, 2013 National Institute of Allergy and Infectious Diseases (NIAID)

Bethesda, MD Towards Earlier Involvement of Children and Pregnant Women in Trials of New TB Drugs Lecture: “TB in Pregnant Women”

May 23, 2013 National Institute of Allergy and Infectious Diseases (NIAID)

Bethesda, MD Towards Earlier Involvement of Children and Pregnant Women in Trials of New TB Drugs Group Leader of Expert Consensus Panel for Pregnant Women

July 25, 2013 Johns Hopkins School of Medicine

Baltimore, MD Medical and Educational Perspectives (MEP) 2013 Lecture: ME:210.699: “Medical Design Initiative: Low-Cost Solutions to Global Health Challenges”

September 11,2013 Johns Hopkins School of Medicine

Department of Pathology Inaugural Pathology Education Symposium Baltimore, MD Lecture: “Laboratory Capacity Building for International Clinical Research: the JHU-BJMC Pune, India Example”

November 3, 2013 44th Union World Conference on Lung Health

Paris, France Invited speaker for symposium on “Best practices in implementing TB/HIV collaborative activities in maternal and child health settings” Lecture: “Integrating Active Tuberculosis Case Finding and Isoniazid Preventive Therapy with

Antenatal Services”

Page 25

November 4-10, 2013 Johns Hopkins School of Nursing Course

Baltimore, MD Global Tuberculosis (TB) Clinical Management and Research Lectures: “Latent TB in India” and “Example Research Solutions for India”

November 5, 2013 Johns Hopkins School of Medicine

Baltimore, MD Global Health Selective Lecture: “Global Health Opportunities: Conducting International Health Work from the US”

November 12, 2013 Johns Hopkins Bayview Medical Center

Baltimore, MD Department of Medicine Grand Rounds Lecture: “Conducting HIV/TB Research in India: Challenges and Opportunities”

November 18, 2013 ACTG Scientific Retreat

Washington, D.C. Invited plenary speaker Lecture: “Overview of HIV-related Cardiovascular and Metabolic Complications in Non-US Settings”

November 19, 2013 ACTG Scientific Retreat

Washington, D.C. Invited plenary speaker Lecture: “TB in Pregnant Women: Research Priorities”

December 3-4, 2013 Makerere University

Kampala, Uganda IMPAACT P1078 Protocol Training Leader

December 6-7, 2013 Perinatal HIV Research Unit

Chris Hani Barawanath Hospital Johannesburg, South Africa IMPAACT P1078 Protocol Training Leader

January 31, 2014 International Science Symposium on HIV and Infectious Diseases

The Accord Metropolitan Hotel Chennai, India Lecture: “Integrating Prevention and Treatment of HIV/TB in Pregnancy”

February 6, 2014 Delhi Strategy Session of the Global US India BioPharma and Healthcare Summit

Organized by the US-India Chamber of Commerce with McKinsey and Company Oberoi Hotel

Page 26

New Delhi, India Invited Roundtable Discussant

February 19-24, 2014 TIME: Global Health 4 Day Workshop

Lead small group discussions to expand students’ understanding of the global determinants of health

March 3-6, 2014 21st Conference on Retroviruses and Opportunistic Infections (CROI)

Boston, MA Oral Abstract Moderator Topic: “Crucial Issues in Mother-to-Child Transmission (MTCT), Maternal Health, and HIV Treatment in Children”

March 18, 2014 24th Annual Clinical Care of the Patient with HIV Infection

Renaissance Baltimore Harborplace Hotel Baltimore, MD Lecture: “Managing Opportunistic Illnesses in 2014”

April 21, 2014 Medical and Educational Perspectives, Inc.

Johns Hopkins School of Medicine Baltimore, MD Panel participant: “Identifying Global Trends and Gaps”

April 24, 2014 Johns Hopkins School of Medicine

Center for TB Research Baltimore, MD Lecture: “Inflammatory Markers and Incident TB: An International Case-Control Study”

May 10, 2014 Jawaharlal Institute of Postgraduate Medical Education & Research

RePORT Meeting Pondicherry, India Lecture: “Grant Writing: The Clinician Researcher Perspective”

May 12, 2014 Hinduja Hospital

Mumbia, India Lecture: “TB in Pregnancy”

June 11, 2014 ICOHRTA-Fogarty Training Program

Lecture: “Conducting HIV Research Through the US and India HIV Clinical Trials Units”

June 13, 2014 Johns HopkinsTB Research Annual Scientific Meeting

Baltimore, MD Lecture: “Vitamin D and TMEM16J host variants associated with Tb and death in HIV infected and

Page 27

exposed infants”

OTHER PROFESSIONAL ACCOMPLISHMENTS Clinical Research: Clinical Trial Protocol Leadership in NIH-funded International HIV Trials Networks 2007-present Chair, IMPAACT P1078, A Randomized Clinical Trial to Evaluate the Safety of

Immediate (antepartum-initiated) Versus Deferred Reduction in TB Incidence and Mortality Among HIV- Infected Women and Their Infants in High TB Incidence Settings

2008-present Protocol Vice-Chair of ACTG 5274, Reducing Early Mortality Among Patients with

Advanced HIV Disease: A Randomized Strategy Trial Comparing the Safety and Efficacy of an Individualized Patient TB Treatment Approach to a Public Health Pre-emptive TB Treatment Approach in Resource-Limited Settings (REMEMBER)

2008-present Protocol Vice-Chair ACTG 5263, A Randomized Comparison of Three Chemotherapy Regimens as an Adjunct to Antiretroviral Therapy for Treatment of Advanced AIDS-KS in

Resource-Limited Settings 2008-2012 Co-investigator ACTG 5267, A Phase I, Safety, Tolerability, and Pharmacokinetic

Interaction Study of Single-Dose TMC207 and Efavirenz in Health Volunteers 2008-2012 Co-investigator ACTG 5253 Sensitivity and Specificity of Mycobacterium Tuberculosis Screening and Diagnostics in HIV-Infected Individuals 2009-present Protocol Vice Chair ACTG 5279, Phase III Clinical Trial of Short-Course

Rifapentine/Isoniazid for the Prevention of Active Tuberculosis in HIV-Infected Adults with Latent Tuberculosis Infection

2010-2013 Co-investigator IMPAACT P1091 Administration of Polysaccharide or Conjugated

Pneumococcal Vaccines to HIV-Infected Pregnant Women: Safety and Magnitude, Persistence, and Transplacental Transfer of Vaccine-serotype pneumococcal anti-capsular Antibodies

2012-present Co-investigator IMPAACT P1026s, Pharmacokinetic Properties of Antiretroviral Therapy

in Pregnancy. 2012-present Co-Investigator, IMPAACT CS4108 Protocol Team, Diagnosis of Intrathoracic

Tuberculosis in HIV-infected and Uninfected Children Using Novel Sampling Strategies and the GeneXpert® MTB/RIF Assay

Other Dec 1-12, 2010 Invited by NIAID, NIH to be a part of a NIH delegation to assess scope of TB research in

India. Accompanied the Deputy Director of the Division of AIDS, the Associate Director of International Health Programs, NIAID and other NIH delegates on site visits to 15 Indian institutions throughout the country

2011-2012 Selected to participate in the Johns Hopkins School of Medicine’s Office in Science and

Medicine (OWISM) Leadership Program for Women Faculty.

Page 28