curriculum vitae - uaf.edu€¦ · web viewliving in a seasonal world: ... drew kl. 1h-nmr...

Kelly L. Drew, Ph.D. May 9, 2023Curriculum Vitae

CURRICULUM VITAEKelly L. Drew, Ph.D.

Personal:

Born: September 19, 1959

Mailing Address: Department of Chemistry and BiochemistryInstitute of Arctic BiologyBox 757000902 N. Koyukuk DriveUniversity of Alaska FairbanksFairbanks, AK 99775-7000

Fax: 907 474-7666E-Mail: [email protected]: 907 474-7190

Home Address: P.O. Box 81185Fairbanks, AK 99708

Education:

1981 B.S. PsychologyUniversity of Alaska Fairbanks, Fairbanks, AK

1982-1984 Ph.D. Candidate, PharmacologyMount Sinai School of MedicineNew York, New YorkAdvisor: Stanley D. Glick, M.D., Ph.D.

1984-1987 Ph.D. PharmacologyAlbany Medical CollegeAlbany, New YorkAdvisor: Stanley D. Glick, M.D., Ph.D.

Professional Training:

1987-1990 Post-doctoral FellowDepartment of PharmacologyKarolinska InstituteStockholm, SwedenAdvisor: Urban Ungerstedt, M.D., Ph.D.

1990 - 1993 Research AssociateInstitute of Arctic Biology

University of Alaska Fairbanks, Fairbanks, AK

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Professional Appointments:

1993 -1998 Research Assistant ProfessorInstitute of Arctic BiologyUniversity of Alaska Fairbanks, Fairbanks, AK

1998 –July 2002 Assistant ProfessorJuly 2002-2008 Associate Professor (Tenured)July 2008-present Professor

Department of Chemistry and BiochemistryInstitute of Arctic BiologyUniversity of Alaska Fairbanks, Fairbanks, AK

2001 – 2011 Adjunct Assistant Professor Department of PathologyCase Western Reserve University

Teaching:

Honors/Awards/Fellowships:

2000-2001 Outstanding Advisor Award, UAF2000 Laboratory Equipment for Chemistry 103 and 104: Basic Introductory

Chemistry and Beginnings in Biochemistry ($8,400; funded by CSEM)2000 Fellow, Educational Reform Institute, Oshkosh, Wisconsin2001 Fellow, Summer Institute for the Teaching of Ethics, Snowmass, CO2005 Dennis Demmert Award for supporting Native and rural students at UAF2006 Emil Usibelli Distinguished Award for Teaching. 2006 Sven O.E. Ebbesson Neuroscience Award2007 Alumni Achievement Awards for Business and Professional Excellence2015 Sidney McNairy Mentoring Award

Teaching Support:

Funded Research for Undergraduates1998-1999 University of Alaska Fairbanks

Undergraduate Research (Bevin McNally – Neuroscience)$5,000 (1998-1999)

1999 American Heart Association Summer Intern (Margaret Krieg – Undergraduate – Chemistry)$3,000 (Summer 1999)

2000 American Heart Association Summer Intern (Allison Kelliher – Undergraduate - Indigenous Medicine)$3,000 (Summer 2000)

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2001 American Heart Association Summer Intern (Ryan Corrick – Undergraduate - Chemistry)$3,000 (Summer 2001)

2003-2004 Alaska EPSCoRResearch for Undergraduates

Maegan Weltzin – (Undergraduate – Chemistry)$10,000 (Spring and Summer 2003, Summer 2004)Ben Warlick – (Undergraduate – Chemistry)$5,000 (Spring 2003)

NIH Supplement for Underrepresented Minorities(Ben Warlick – Undergraduate – Chemistry)$60,000 (Fall 2003 – Fall 2005)(Adrienne Orr – Postgraduate – Chemistry, BS)$59,000 (Fall 2003 – Fall 2004)

2003-2004 Alaska BRINResearch for Undergraduates

Maegan Weltzin – (Undergraduate – Chemistry&Biochem)$5000 (Summer 2004)Johanna Fritsche –(Undergraduate – Anthropology)$5000 (Summer 2004)

2004-2005 Alaska INBREResearch for Undergraduates

Ben Warlick – (Undergraduate – Chemistry&Biochem)$2500 (Fall 2004)Lonita Lohse –(Undergraduate – Chemistry&Biochem)$2500 (Fall 2004)Shauna Sagmoen –(Undergraduate – Interdisciplinary)$2500 (Summer 2005)

2007-2009 Center for Research ServicesUndergraduate Research Competition

Velva Combs- (Undergraduate – Biology & Wildlife)$2500 (2007/2008) – 2nd placeZac Carlson – (Undergraduate – Chemistry)$2500 (2008/2009)Jasmine (Davis) Olson$2500 (2010/2011)

2009-2011 Center for Research ServicesUndergraduate Research Competition

Colleen Bue- (Undergraduate – Biology & Wildlife)

Alaska Space Grant Program and Alaska INBREUndergraduate Research Competition

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JoAnna Carpluk (Undergraduate – Psychology); co-mentored by Lori Bogren

2011-2012 Alaska Space Grant ProgramUndergraduate Research Competition

Erin Johnson (Undergraduate – Biology); co-mentored by Lori Bogren


Isaac Baily (Undergraduate – Chemistry&Biochemistry)


Katrina Dowell (Undergraduate – Biology)

Teaching Experience and Certification:

Graduate: Neuropharmacology/pharmacokinetics, Nurse Anesthetist Program, Albany Medical CollegePharmacology of Alcohol and Alcoholism, UAF Basal Ganglia, Stroke; WWAMI Medical School, Anchorage Alaska, guest lecturerNeurochemistry, UAF Receptor Pharmacology, UAF

Undergraduate (100-400)/Graduate (600):Chemistry and Society (Chem F100X), UAF, 4 hrsMultiple Intelligences (ED F495), UAF, 3 credit hrs Basic General Chemistry (Chem F103X), UAF, 4 credit hrsBeginnings in Biochemistry, (Chem F104X) UAF, 4 credit hrsBiochemistry (Chem F451), UAF, 3 credit hrsBiochemistry Lab (Chem F456, 3 credit hrs)General Chemistry (Chem F105X, UAF, 4 credit hrs)Neurochemistry (Chem 474 and 696, UAF, 3 credits)Receptor Pharmacology (Chem 493 and 693, 3 credits)Biochemistry Colloquium – Professional development (Chem 688, 1 credit)

Certification: 1997 Alaska State Certification in Secondary Science Education (Chemistry)

Postdoctoral Fellows/Research Associates Mentored (Current Position):1993-1998 Yong Hu, M.D. (Clinical Support Consultant, Solucient, LLC)1998-1999 Peter Osborne, Ph.D. (Asahikawa Medical School, Hokkaido, Japan,

Research Scientist)1996-1998 Oivind Toein, Ph.D. (Research Associate, IAB) 2001-2004 YiLong Ma, Ph.D. (Research Associate Professor, IAB)

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2001-2004 Brian Rasley, Ph.D. (Associate Professor, Dept. Chemistry and Biochemistry, UAF)

2004-2006 Sherri Christian, Ph.D. (Assistant Professor, Memorial University)2007 Sun June, Ph.D. (Retired)2011 Tulasi R. Jinka, Ph.D. (Research Investigator, Department of Emergency

Medicine, University of Michigan)2013-2014 Lori Bogren, Ph.D., Post-doctoral Fellow, University of Colorado2013-present Zeinab Barati, Ph.D.2014-present Bernard Laughlin, D.O.

Graduate Students Trained/Current Position:1997-2001 Rafaella Stimmelmayr, Ph.D. Wildlife Veterinarian and Research Biologist at

North Slope Borough, Research Scientist, IAB1999-2001 Fang Zhou, MS, Technician, NIH2001-2005 Austin Ross, Ph.D., High School Science Teacher, St. Christopher's School,

Richmond, VA.2001-2005 Huiwen Zhao, Ph.D. Post-doctoral fellow, UCSD, laboratory of Dr. Gabbriel

Haddad2001-2005 Bongchu Chi, M.S., Analytical chemist, Flint Hills Petroleum, Alaska 2005-2008 Lesa Hollen, M.S.2008-2010 Joel Vonnahme, M.S. PhD candidate, University of Hawaii2005-2010 Tulasi R. Jinka, PhD. (Research Scientist, U. Michigan)2010-2013 Lori Bogren, PhD (Data Scientist, Verizon)2010-2013 Velva Combs, MS2010-2014 Zac Carlson, MS Technician, (Analytical Sciences Laboratory, University of

Idaho)2011-2017 Saurav Bhowmick, PhD (Post-doctoral Fellow, John F Kennedy Medical

Center)2012-present Carla Frare, PhD2014-present Sarah Rice, PhD2015-2017 Isaac Bailey, MS (PharmD program, Spokane, WA)2014-present Bernard Laughlin, PhD

Graduate and Medical Student Rotations/Training:1997 Kimberly Clapp, Ph.D. Student, Study of ultrastructure around microdialysis

probes (Clapp-Lilly et al., 1999)1997 Zachary Katz, M.S. student, Study of extracellular GABA in hibernating

ground squirrels (Osborne et al., 1999)1999-2000 Carol Stewart, D.V.M. Clotting times during hibernation2005 Bodo Schulenburg, M.S. student Private University Witten/Herdecke, Faculty

for Natural Sciences, Institute for Neurobiochemistry, MAPK signaling in hibernation

2007 Kimberly Iceman, B.S. cardiac arrest in AGS2010 Carla Frare, Inflammatory response following hemorrhagic shock in AGS2013 Lucille A. Moore, Neurochemical pathway of A1AR-induced torpor2018 Yige Huang, space torpor

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Graduate Student Committees:1995-1997 Thesis Committee, Lars Ebbesson, Interdisciplinary Neuroscience, UAF

(M.S.)1996-1997 Thesis Committee, Philip Shelton, Psychology, UAF (M.S.)1997-1999 Thesis Committee, Stephanie Dloniak, Biology, UAF (M.S.)1996-1999 Thesis Committee, Kimberly Clapp, Biochemistry and Molecular Biology,

UAF, (Ph.D.)1997-1999 Thesis Committee, Nancy Matton, Biochemistry and Molecular Biology,

UAA, (Ph.D.)1995-2001 Thesis Committee, Michael Sullivan, M.D., Neuroscience, UAA, (Ph.D.)1998-2001 Thesis Committee, Jo Simmonetti, Biochemistry and Molecular Biology,

UAA, (Ph.D.)1998-2001 Thesis Committee, Zhengyu Wei, Biochemistry and Molecular Biology,

UAF, (Ph.D.)1998-2001 Thesis Committee, Chance Riggins, Chemistry, UAF (M.S.)1998-2005 Thesis Committee, Chris Whittle, Chemistry, UAF, (Ph.D.)2001-2001 Thesis Committee, Shawna Karpovich, Biology and Wildlife, (Ph.D.)1997-2001 Thesis Committee (co-Chair), Rafaella Stimmelmayr, Biology and Wildlife

UAF, (Ph.D.)1999-2001 Thesis Committee (Chair) Fang Zhou, Biochemistry and Molecular Biology

UAF, (M.S.)2000-2002 Thesis Committee, Shelly Stewart, Biochemistry and Molecular Biology,

UAF (M.S.)2003 Thesis Committee, Shawna Karpovich, Biology and Wildlife, UAF (M.S.)2001-2005 Thesis Committee (Chair), Austin Ross, Biochemistry and Molecular Biol.

UAF, (M.A.,Ph.D.) 2001-2005 Thesis Committee (Chair), Huiwen Zhao, Biochem. and Molec. Biol. UAF,

(Ph.D.)2001-2003 Thesis Committee, Anna Godduhn, Interdisciplinary Environmental Science,

UAF (M.S.)2002-2003 Thesis Committee, Sirisha Nerella, PhD in Engineering (PDE)2002-2005 Thesis Committee (Chair), Bongchu Chi, Chemistry, UAF (M.S.)2002-2006 Thesis Committee, Xioaming Zhao, Biochem. and Molec. Biol. UAF, (Ph.D.)2003-2005 Thesis Committee, Sarah Dirschel, Biochem. and Molec. Biol. UAA, (Ph.D.)2003-present Thesis Committee, Elvin Brown, Biochem. and Molec. Biol. UAA, (Ph.D.)2003-2006 Thesis Committee, Yeganeh Ataian, Biochem. and Molec. Biol. UAA,

(Ph.D.)2003-2007 Thesis Committee, Dana Green, Biology and Wildlife, UAF (Ph.D.)2003-2005 Thesis Committee, Kristian Swearingen, Biochem. And Molec. Biol. UAF,

(M.S.)2004-2005 Thesis Committee, Asha Suryanarayanan, Biochem. and Molec. Biol. (Ph.D.)2004-2005 Thesis Committee, Prasad Joshi, Biochem. and Molec. Biol. UAF, (Ph.D.)2005-2008 Thesis Committee (Chair), Lesa Hollen, Interdisciplinary degree in

Neuroscience Visualization (M.S.)2005-present Thesis Committee (Chair), Tulasi Ram Jinka, Interdisciplinary degree in Lab

Animal Neuroscience (PhD; Post-doc University of Michigan)2006-2008 Justin Breuhner (M.S. Biology and Wildlife; RN; Fairbanks Memorial

Hospital)

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2006-2009 Cord Brundage (M.S. Biology and Wildlife; PhD; DVM)2007-2009 Dan Kirschner (Ph.D. interdisciplinary in Analytical Biochemistry2007-present Melony Richter (PhD Biology and Wildlife)2009-2013 Lori Bogren (Chair, PhD Biochem and Molec. Biol)2009-2012 Joel Vonnahme (Chair, MS Biochem and Molec. Biol)2009-2013 Velva Combs (Chair, MS INDS Neuroscience)2009-2014 Zac Carlson (Chair, MS, Chemistry) 2011-2017 Saurav Bhomick (Chair, PhD, B&N)2012-present Carla Frare (Chair, PhD, B&N)2013-2016 Alex Tackett (M.S. B&N)2013-2015 Sarah Johansen (M.S. Biology and Wildlife)2013-2017 Mitch Reed (PhD, Biology and Wildlife)2014-present Sarah Rice (Chair, PhD, B&N)2015-2017 Isaac Bailey (Chair, MS, B&N)2014-present Bernard Laughlin (Chair, PhD, B&N)

High School and Undergraduate Students Trained (undergraduate research), current position or project title:

1991-1995 Terri Fitka,* BS psychology1995-1997 Zachary Katz, BS chemistry, PhD Chemistry 1995-1996 Denise Newman*, BS psychology1995-1996 Alex Dugaqua*, biology, AA fisheries1995-1997 Chena Bryan*, BS biology, Ph.D. Program in Neuroscience, Univ Hawaii1995 Crystal Rublee, BS biology, O.D. 1998 Maggie Kreig, BS chemistry 1995; 1998-1999 Nikoosh Carlo*, psychology, B.S., Ph.D. Neuroscience, UCSD; Arctic Policy

fellow in the Office of Polar Programs, NSF; Senior Advisor for the Arctic Council and Chief of Staff to the Chair of the Senior Arctic Officials, Senior Climate Adviser under Governor Bill Walker

1998-1999 Bevin McNally, neuroscience (interdisciplinary) 1998-2000 Allison Kelliher*, indigenous medicine (interdisciplinary) B.S., MD, Primary

Care Physician, South Central Foundation 1999-2001 Ryan Corrick, chemistry, BS, MD, PhD, University of Alabama2000-2002 Grant Wright, chemistry, BS2000-2002 Zach Hill, Chemistry, BS, PhD, University of Washington, post-doc UCSF2000-2003 Kristian Swearingen, Chemistry, BS, PhD, University of Washington, post-

doc, Institute of Systems Biology 2000-2004 Lesa Hollen, BS biology, MS Neuroscience Visualization, UAF2001-2003 Maegan Weltzin*, BS, BMB PhD, post-doc Barrow Research Institute2001-2002 Charles Peele*, BS political science2002-2004 Adrienne Orr*, Ph.D. Molecular Pharmacology, Stanford University, post-

doc UCSF, Allergan Project Manager2002-2005 Bongchu Chi, BS chemistry, Technician, Flint Hills Petroleum2002-2005 Ben Warlick*, BS chemistry, PhD University of Illinois at Urbana-

Champaign. Sr. Product Development Scientist; Sigma-Aldrich2003-2005 Lonita Loshe*, BS chemistry, Science teacher, Gospel Fellowship

Association missionary

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2004-2005 Johanna Herron, BS anthropology, Technician, UAF CANHR; Alaska State Lead, Farm to School Coordinator, Alaska Division of Agriculture

2005-2006 Shauna Sagmoen*, BS INDS Neurosignaling, degree in progress (co-mentored with Dr. Sherri Christian)

2005-2006 Bianca Zuckerman*, High School Student, MRI measures of blood flow in hibernation, PT program, University of Texas, pediatric physical therapist.

2005-2006 Ann Wilson*, BS chemistry, science teacher2007 Theresa Wallace, high school student, Neuroplasticity in hibernation2007 Velva Combs*4, BS biology, global ischemia in ground squirrels, MS, UAF

(2013), applying to vet schools.2007 Lisbet Norris, CNS regulation of metabolic suppression in ground squirrels.

(mentored by Ph.D. student Tulasi Jinka)2007 Grant Wright, Brain slice energetics using 31P NMR (co-mentored by B.

Rasley), Flint Hills Refinery.2008-2009 Laura Mather, Arctic ground squirrel neural stem cell cultures resist NMDA

excitotoxicity (mentored by PhD student Kim Iceman)2008 Joel Vonnahme, BS biology, Arctic ground squirrel neural stem cell cultures,

University of Hawaii, PhD program2008-2009 Zac Carlson4, adenosine A1 receptor sensitization in energy homeostasis, MS

program, UAF2008-2009 Lindy Smith, Arctic ground squirrel neuralstem cell cultures and energy

homeostasis, UAF research technician2008-2009 Jeff Danielson, high school student, seasonal cycles of food intake in Arctic

ground squirrels2009-2010 Jasmine Davis4, circannual rhythm of resting body temperature predicts

sensitivity to cooling effects of A1 adenosine receptor agonists, UW Dental School, DDS, 2015

2009,2011 Jo Anna Carpluk*2,3, Resistance to multi-organ failure in Arctic ground squirrel – Nursing School, UAF

2009-2011 Levi Wegner*2, iNOS and neuroglobin expression in Arctic ground squirrel in relation to ischemia tolerance, Medical Technologist Program, UAA

2010 Melissa Pietila, Therapeutic hypothermia, BS program UAF, pre-vet2011 Sigourney Walker*2, Adenosine kinase expression in summer and winter

AGS – music therapist 2011 Hassan Kaplan*2, Translating the hibernation phenotype to rats using every

other day feeding, BS program UAF2011 Colleen Bue4, Ambient temperature preference in hibernating AGS2012 Kasie Baker1, iNOS and neuroglobin expression in Arctic ground squirrel in

relation to ischemia tolerance (co-mentored by Saurav Bhowmick)2012 Lucille Moore1, Neurochemical anatomy of torpor onset in AGS, PhD

program OHSU2012 Erin Johnson3, Metabolomic profile of resistance to hemorrhagic shock in

AGS (co-mentored by Lori Bogren) – teaching English as a second language in Japan.

2013 Madison Wilson5, mitigating cardiovascular effects of A1AR agonist-induced cooling

2013 Isaac Bailey*2,3, formulations for lipophilic A1AR agonists, MS program in biochemistry and Neuroscience, UAF

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2013 Paula Martin*, translating therapeutic hypothermia for stroke, BS chemistry, UAF

2014 Katrina Dowell3, cardiac arrhythmias associated with 6N-cyclohexyladenosine-induced cooling of core body temperature. Co-supervised with Bernard Laughlin and Zeinab Barati

2015 Moriah Hunstiger5, Novel object recognition for assessing cognitive effects of aging. Co-supervised with Bernard Laughlin

2016 Sierra Tagaban*5, Novel object recognition for assessing cognitive effects of cooling. Co-supervised with Bernard Laughlin

2016-present Monica Mikes*1,4,6 Metabolomics of wild and free-ranging arctic ground squirrels. Co-supervised with Sarah Rice

2016-2018 Mackenzie Jenkins4,5, Brain regions involved in seasonal sensitivity to drug-induced torpor. Co-supervised with Carla Frare

2017-present Michael Kaden-Hoffman, translating hibernation for targeted temperature management.

*under-represented minority students1INBRE funded2URMA funded3Alaska Space Grant funded4Vice Chancellor for Research or URSA undergraduate research award5Chemistry 4886BLaST

Research:

Honors/Awards/Fellowships:

1982-1984 Predoctoral fellowship; PHS (#5T32-GM07163)1984-1987 Trustee scholarship; Albany Medical College1989-1990 Åke Wiberg Foundation Fellowship, Stockholm, Sweden1987-1990 Visiting Scientist fellowship; Karolinska Institute2002 Outstanding Advisor Award, UAF2005 Dennis Demmert Award from UAF Rural Student Services 2006 Usibelli Teaching Award ($10,000)2006 1st annual Sven Ebbesson Award for Excellence in Neuroscience2007 UAF Alumni award for Business and Professional Excellence 2010, 2011 Nominated for NSF presidential award for mentoring2014 The Sidney A. McNairy, Jr. Mentoring Award 2018 State of Alaska Innovator Hall of Fame

Research Support:

Postdoctoral:

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1988 -1990 National Institutes of Health, Individual National Research Service Award NS08240, Neurochemistry of postural Asymmetries Measured using in vivo Microdialysis

Principal Investigator:1992-1993 National Science Foundation IBN 912-1-221, GABA and Dopamine Release

in Coho Salmon Brain $40,000

1992 – 1995 National Institutes of Health A609483 (Shannon Award), GABA and Dopamine Release in Aged Rat Striatum, $100,000

1995 – 1998 American Heart Association, Natural Tolerance to Cerebral Ischemia and Hypothermia, $120,000

1998 – 2001 American Heart Association, Natural Tolerance to Cerebral Ischemia and Hypothermia, (Competitive Renewal) $145,000

2001-2004 Office of Naval Research, Central Nervous System Regulation of Metabolic Down Regulation During Hibernation: A Microdialysis Study using Capillary Electrophoresis with Laser Induced Fluorescence Detection, $300,000.

2002-2004 Office of Naval Research Supplement, Study of Metabolic and CNS Suppression during Hibernation Using Microdialysis and Capillary Electrophoresis with Laser-Induce Fluorescence Detection $27,416

2002-2004 Defense Advanced Research Projects Agency, Effects of Hibernation on Retention of Active Avoidance Tasks, $100,000

2004-2007 Army Research Office Life Science Division, Central Nervous System Regulation of Metabolic Suppression for Combat Casualty Care, $350,000.

2010-2017 National Institutes of Health (NINDS, R15, R15NS070779, including diversity supplement), Restricted diet and adenosine receptor activation: Therapy for brain ischemia, $910,000.

2012 Bianca M. Zuckerman Academic Excellence/Programmatic ResearchMRI – Endowment to provide programmatic/research support to undergraduate students at UAF (Magnetic Resonance Imaging(MRI) Research within the Institute of Arctic Biology).

2013-2017 National Institutes of Health (NINDS, R03, RO3NS081637), Brain regions involved in seasonally dependent A1AR agonist-induced torpor, $150,000.

2013-2018 National Science Foundation, (IOS-1258179) Cross Talk between Metabolism and the Nervous System via NMDAR Initiates Interbout Arousal In Hibernating Ground Squirrels, $963,029.

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2014-2015 National Institutes of Health (NIH, RO1, R01MH067698), Progestogens’ non-classical effects and mechanisms for social & mood processes, $302,940.

2017 Alaska Space Grant Program (RIS) (Alaska NASA EPSCoR Program (NNX13AB28A), Optimizing safety and efficacy of a drug-induced hibernation-like state in rats, $20,000

2017 National Institutes of Health (NIH, R41, R41HL135964), Development of the first thermolytic to suppress shivering and seizure, $298,871 to Be Cool Pharmaceutics LLC; $129.772 subaward to UAF.

2018-2023 National Institutes of Health (NIGMS) [PAR16-415] - CENTERS OF BIOMEDICAL RESEARCH EXCELLENCE (COBRE) (P20)Mammalian Hibernation Research-A Path Towards a Center for Transformative Research in Metabolism -Submitted

Co- Investigator 2003-2004 CBD/Army Small Business Innovation Research (SBIR) program,

Identification of Compounds to Induce Suspended Animation or Hypometabolism. PI: Karl Johe, Neuralstem Inc., Gaithersberg, MD, $119,419

2000- 2005 National Institutes of Health (NINDS, NIMH, NCRR), Alaskan Basic Neuroscience Program Project leader on “Mechanisms of Neuroprotection During Hibernation and Arousal”, $1,500,000 for project ($7,500,000 for entire program)

2003-2004 National Institutes of Health (NINDS, NIMH, NCRR), Alaskan Basic Neuroscience Program, “Mechanisms of Neuroprotection During Hibernation and Arousal” Research Supplement for Underrepresented Minorities, $109,107

2003-2005 National Institutes of Health (NINDS, NIMH, NCRR), Alaskan Basic Neuroscience Program, “Mechanisms of Neuroprotection During Hibernation and Arousal” Research Supplement for Underrepresented Minorities, $60,198

2004-2007 Research Supplement for Individuals with Disabilities to 1-R15-NS048873-01 $205,215.

2006- 2008 National Institutes of Health (NINDS, NIMH, NCRR), Advancing UAF SNRP. Project leader for “Mechanisms of Neuroprotection in Arctic ground squirrels”, $300,000 for project

2005-2011 US Army Medical Research and Materiel Command grant # 05178001, $9,197,000. Hibernation Genomics: Determination of cellular and molecular basis for preventing cardiac arrhythmias under conditions that produce

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arrhythmias in humans and for protecting the brain from injury due to cardiac arrest or stroke. Project leader ($1,585,040)

2009-2011 US Army Medical Research and Materiel Command grant # 10069001 $1,357,00. Hibernation Genomics: Mechanisms for Metabolic Suppression and Neural Protection (2010 Supplement). Project leader ($187,176).

2016-2018 National Institute of General Medical Sciences of the National Institutes of Health under Award Number U54GM115371, Faculty Pilot Award, Cardiac Arrest Survival Rate & Determinant Factors in Rural Alaska, Co-I ($135,000)

Invited Seminars/Platform Presentations:

S1. Drew K.L., Origin of GABA sampled using microdialysis, Maryland Psychiatric Research Institute, May, 1992.

S2. Drew K.L., Hibernation: A model for studying the brain’s tolerance to stroke. University of Alaska Anchorage, Biology Research and Graduate Seminar Series, Sept. 25, 1998

S3. Drew K.L., Rice M.E., Frerichs K.U. and Hallenbeck J.M., 1999, Stroke therapies from hibernating squirrels, Winter Conference on Brain Research, Snowmass, CO, Jan 23-30.

S4. Drew K.L., Osborne P.G., Hu Y., Stimmelmayr R., Barnes B.M., 1999, Hibernation: a natural model of tolerance to brain trauma. Hibernation and Adaptations to the Cold, Estes Park, CO, May 20-22.

S5. Drew K.L., Osborne P.G., Hu Y., Stimmelmayr R., Barnes B.M., Hibernation and Tolerance to Brain Trauma, 50th Arctic Science Conference, Science in the North: 50 Years of Change. Denali National Park and Preserve, Alaska, Sept. 19-22, 1999.

S6. Duffy L, Drew K, Kuhn T and Bult B, Neuroscience Research at the University of Alaska Fairbanks. May 5, 2000.

S7. Drew K.L., Neuroprotective correlates of hibernation. National Institute of Mental Health, August, 1999.

S8. Drew K.L., Hibernation, a natural model of neuroprotection, National Institute of Deafness and Other Communication Disorders, Sept. 23, 2000.

S9. Drew K.L. Hibernation: A model of neuroprotection, Institute of Pathology, Case Western Reserve University, April 16, 2001

S10. Drew K.L. Hibernation: Microdialysis in hibernating ground squirrels, Dept of Psychiatry, Case Western Reserve University, April 20,, 2001

S11. Drew K.L., Microdialysis, tissue trauma and glutamate in hibernating brains. 9th Annual Meeting On In Vivo Methods For Monitoring Molecules In Neuroscience. Dublin, June 18, 2001.

S12. Drew K.L., Hibernation and Neuroprotection. Alaskan Summer Neuroscience Conference, Fairbanks, July 29, 2001

S13. Drew K.L. Antioxidant Protection in Hibernation. Workshop on comparative aspects of oxidative stress. La Paz, Mexico, October, 2001, Session Chair.

S14. Drew K.L. Neuroprotection in Hibernation. Life Science Seminar Series, Institute of Arctic Biology, University of Alaska Fairbanks, Dec. 9, 2001

S15. Drew K.L. Hypoxia Tolerance in Hibernation. The less you want the more you have. Winter Conference on Brain Research. Snowmass, CO, Jan 27, 2002

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S16. Drew K.L. and Green T.K., Microdialysis: Theory, Application and Coupling to Capillary Electrophoresis with Laser-Induced Fluorescence Detection, Center for Nanosensor technology, University of Alaska Fairbanks, Feb 7, 2002.

S17. Drew K.L. Memory, Learning and Hibernation, PI meeting for Continuous Assisted Performance Program, Defense Advanced Research Projects Agency (DARPA). New Orleans, March 25, 2002.

S18. Drew K.L. Hibernation a Natural Model of Neuroprotection. Alaska Summer Neuroscience Conference. Fairbanks, Alaska, July 14-15, 2002.

S19. Drew K.L., Neuroprotection in Hibernating Arctic Ground Squirrels (Spermophilus parryii): Metabolic Suppression. Advanced Technology Applications for Combat Casualty Care (ATACCC). St. Pete Beach, Florida, Sept. 9-11, 2002

S20. Drew K.L., Learning and Memory in Hibernation. PI meeting for Continuous Assisted Performance Program, Defense Advanced Research Projects Agency (DARPA). Honolulu, Hawaii, Sept 22-26, 2002.

S21. Drew K.L. Neuroprotection in Hibernation: Pacific Biomedical Research Center, University of Hawaii, Sept 27, 2002.

S22. Drew K.L., Neuroprotection in Hibernation: Is it Clinically Relevant? University of Miami, Neurology Grand Rounds. October 31, 2002.

S23. Drew K.L., Neuroprotection in Hibernation: A comparative Perspective. University of Miami School of Marine Biology. October 31, 2002

S24. Drew K.L. JNK activation during arousal from hibernation: a pivotal pathway of regeneration. University of Nebraska Omaha Center for Neurovirology and Neurodegenerative Disorders. August 21, 2003

S25. Drew K.L. Novel therapeutics from hibernating brain? Neuralstem Inc. Gaithersburg, MD. August 23, 2003.

S26. Drew K.L. Hypoxia Tolerance in Mammalian Heterotherms. Journal of Experimental Biology Discussion Meeting, Defenses Against Brain Hypoxia: Molecule to Organism, Organised by R.G. Boutilier and P.L. Lutz, September 13th – September 17th 2003, Cicalino, Italy

S27. Drew K.L. Living without in Hibernation. Winter Conference on Brain Research. Copper Mountain, Colorado, Jan 29, 2004.

S28. Drew K.L. Neuroprotection in Hibernation. Life in the Cold. Vancouver, Canada to Seward, Alaska, July 31, 2004.

S29. Drew K.L. and Edberg R. "Visualizing Chemistry: Tools for the ARSC Discovery Lab", Fairbanks, Alaska, Dec 7, 2004

S30. Drew K.L. Cellular stress and MAPK modulation in Hibernation. Workshop on comparative aspects of oxidative stress. La Paz, Mexico, February 15-19, 2005. Session Chair

S31. Drew K.L. Evidence and Mechanisms of Ischemic Tolerance in Arctic Ground Squirrels. University of Minnesota Duluth Medical School and Department of Biology. Duluth, Minnesota, Oct 7, 2005.

S32. Drew K.L. Neuroprotection in Hibernation and Euthermy. 5th Dutch Endo-Neuro-Psycho meeting Doorwerth, Netherlands, June 7, 2006

S33. Drew K.L. Neuroprotection and Neuronal Plasticity in Hibernation and Arousal. University of Groningen, Groningen, Netherlands, June 15, 2006

S34. Drew K.L. Evidence for and Mechanisms of Tolerance to Global Ischemia In Vivo and Oxygen Glucose Deprivation In Vitro in the Arctic Ground Squirrel. 6th Annual Specialized Programs in Neuroscience Research (SNRP) Conference. Fairbanks, AK, May 31, 2006

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S35. Drew K.L. Super Spermophilus: Neuroprotection in hibernation and euthermy, American Physiological Society, Virginia Beach, VA, Oct. 9, 2006

S36. Drew K.L. Super Spermophilus: Neuroprotection in hibernation and euthermy, EPSCoR Neuroscience/Physiology Seminar series, UAF, Oct. 27, 2006

S37. Warlick B. Rasley B.T. Drew K.L. Some performance characteristics of hand-constructed, low-dead volume, microdialysis probes in: Di Chiara, G., Carboni, E., Valentini, V., Acquas, E., Bassareo, V. & Cadoni, C ed(s). 11th International Conference on In-Vivo Methods, Sardinia, Italy (19-22 May 2006)

S38. Barnes B.M. and Drew K.L. Hibernation Genomics, TATRC Product Line Review, Fredrick, VA, Jan. 9, 2007

S39. Drew K.L. Neuroprotection in Arctic ground squirrels, Stanford University, Feb 6, 2007. S40. Drew K.L. PKC plays a role in neuroprotection in AGS, Institute of Arctic Biology, Oct 19,

2007S41. Drew K.L. Epsilon PKC delays loss of ion homeostasis during oxygen glucose deprivation

in Arctic ground squirrel brain slices. 7th Annual Specialized Programs in Neuroscience Research (SNRP) Conference. New York, NY, August 20-22, 2008

S42. Drew K.L. PKC down regulates ion channels in Arctic ground squirrels during modeled cerebral ischemia. University of Alaska Department of Chemistry and Biochemistry Seminar. Sept. 16, 2008.

S43. Drew K.L. Adenosine an endogenous mediator of torpor in hibernating Arctic ground squirrels. Hypothermia from threat to cure. New York Academy of Sciences. Sept 19, 2008

S44. Drew K.L. Life in the cold breeds tolerance and torpor. Microenvironmentalist group. New York University, Dept of Physiology. Sept. 22, 2008.

S45. Drew K.L. Food for thought: Adenosine, Metabolism, and Brain Activity. Winter Conference on Brain Research. Copper Mountain, CO, Jan 29, 2009.

S46. Drew K.L. Seasonal Sensitization in Purinergic Signaling Permits Adenosine A1 Receptor Activation to Induce Torpor in Hibernating Arctic Ground Squirrels. Metabolic Responses to Extreme Conditions, Big Sky, Montana, April 3, 2011

S47. Drew K.L. Acclimation to cold ambient temperature in the winter season is necessary for adenosine-induced torpor. UA Biomedical Research Conference, Fairbanks, AK May 21, 2012.

S48. Drew K.L. Raising the Dead, UCSD, February 11, 2012S49. Drew K.L. Resistance to cerebral ischemia/reperfusion injury in the arctic ground squirrel

(Urocitellus parryii) does not depend on the hibernation season. 10th International Congress of Neuroethology, College Park, Maryland, August 8, 2012. http://icn2012.umd.edu/

S50. Drew K.L. Potential mechanisms of metabolic suppression downstream of central A1AR activation during onset of torpor. Living in a seasonal world: thermoregulatory and metabolic adaptations. 14th International Hibernation Symposium. Semmering, Austria, August 12, 2012. https://fiwi.vetmeduni.ac.at/?site=symposium3

S51. Drew KL, Jinka TR, Combs V. Translating drug-induced torpor to therapeutic hypothermia. University of Alaska Biomedical Research Conference, Anchorage, Alaska, May 29, 2013

S52. Drew KL, Jinka TR, Combs V. Translating drug-induced torpor to therapeutic hypothermia. IUPS, Birmingham, UK, July 26, 2013

S53. Drew KL, Raising the Dead, Life Sciences Seminar Series, SRI, Menlo Park, CA Feb 6, 2014.

S54. Drew KL, Raising the Dead, Neural Injury and Repair Seminar, UCSF, San Francisco, CA Feb 11, 2014.

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S55. Drew KL, Translating hibernation for therapeutic hypothermia in rural Alaska. Western Alaska Interdisciplinary Science Conference, Kotzebue, AK April 23-25, 2014

S56. Bailey IR, Bogren LK, Drew KL, Targeted temperature management with a novel adenosine agonist. Exp. Biol., San Diego, CA April 26-30, 2014.

S57. Bogren LK, Murphy CJ, Johnston EL, Serkova NJ, Drew KL, 1H-NMR metabolomic biomarkers of poor outcome after hemorrhagic shock are absent in hibernators. Exp. Biol., San Diego, CA April 26-30, 2014.

S58. Bogren LK, Johnston EL, Van Tets IG, LeBlanc AD, Drew KL, Bone density is maintained during forced disuse in hibernators throughout both the active and hibernation seasons. Exp. Biol., San Diego, CA April 26-30, 2014.

S59. Drew KL, Translating CNS control of hibernation for therapeutic hypothermia, in Therapeutic Hypothermia – CNS Regulation and Neurochemical Benefits, K. Drew (Chair), Monitoring Molecules in Neuroscience, Aug. 5, 2014, Los Angeles, CA.

S60. Drew KL, Neuroprotection in Hibernation, One Health Seminar Series, UAF, September 15, 2014.

S61. Drew KL, Translating hibernation for therapeutic hypothermia, European Space Agency Topical Meeting, Frankfurt, Germany, October 15, 2014.

S62. Drew KL, Hibernation and Hypothermia, Thermoregulation and Sleep Seminar Series, Bologna, Italy. Jan. 18, 2015.

S63. Drew KL, Translating Drug-induced hibernation to therapeutic hibernation in Pharmacologically induced hypothermia and clinical implications, Shan Ping Yu (Chair). ASN 2015, Atlanta, GA, March 18, 2015

S64. Drew KL, Central nervous system control of hibernation reveals opportunities for human hibernation. Scandinavian Physiological Society meeting, Aarhus, Denmark, Sept. 19, 2015.

S65. Drew KL, Translating Drug-induced hibernation to therapeutic hibernation, University of Kopasvar, Kopasvar, Hungary, Sept 23, 2015.

S66. Drew KL, Translating CNS control of hibernation to non-hibernating species. 9th meeting of the International Society for Autonomic Neuroscience (ISAN 2015), Stresa, Italy, Sept. 26, 2015.

S67. Drew KL, Translating CNS Control of Hibernation for Treatment of Cardiac Arrest and Stroke, IAB Life Science Hour Seminar Series, University of Alaska Fairbanks, Oct. 2, 2015.

S68. Drew KL, Seasonal influence on A1 adenosine receptor modulation of hibernation in arctic ground squirrels. University of Tromsø. Tromsø, Norway, April 7, 2016

S69. Drew KL, Hibernation for space flight and targeted temperature management. University of Illinois Chicago, Laboratory of Integrative Neuroscience’s Spring Symposium, Chicago, IL, April 14, 2016

S70. Drew KL Seasonal rhythm in adenosine A1 receptor signaling in hibernation. World Sleep 2017, Prague, Czech Republic, Oct. 7-11, 2017.

S71. Drew KL Panelist, Arctic Science & Business / Industry Cooperation breakout session, Arctic Circle, Reykjavik, Iceland, October 15, 2017

S72. Drew KL Thermolytic efficacy and pharmacodynamics of CHA/8SPT in rats and pigs. ESA-Topical Team Workshop on Hibernation and Torpor in Innsbruck, Austria Feb. 10, 2018.

S73. Drew KL Translating CNS regulation of hibernation for targeted temperature management, Department of Cellular & Molecular Physiology, Yale University School of Medicine. New Haven, CT Feb. 22, 2018

S74. Drew KL Seasonal rhythm in A1 adenosine receptor signaling in hibernation. International Conference on Brain Energy Metabolism, Valdivia, Chile, March 10, 2018

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S75. Drew KL Pharmacological and Nutrition-Based Approaches for Sustained Torpor -NASA Ames Space Torpor Workshop, NASA Ames Office of Chief Scientist, Moffett Field, CA, March 13, 2018.

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Publications:

Full-Length Papers:P1. Drew KL, Lyon M, Tietler M, Glick SD, 1986. Asymmetry in D-2 binding in female rat

striata. Brain Res. 363:192-195.P2. Drew, K.L. and Glick, S.D. 1987. Classical conditioning of amphetamine-induced lateralized

and nonlateralized activity in rats. Psychopharmacology. 92:52-57.P3. Glick, S.D., Shapiro, R.M., Drew, K.L., Hinds, P.A. and Carlson, J.N. 1986. Differences in

spontaneous and amphetamine-induced rotational behavior, and in sensitization to amphetamine, among Sprague-Dawley derived rats obtained from different sources. Physiol. Behav. 38:67-70

P4. Drew, K.L. and Glick, S.D. 1988. Characterization of the associative nature of sensitization to amphetamine-induced circling behavior and of the environment dependent placebo-like response. Psychopharmacology. 95:482-487.

P5. Drew, K.L. and Glick, S.D. 1988. Environment dependent sensitization to amphetamine-induced circling behavior. Pharmacology Biochemistry and Behavior 31:705-708.

P6. O’Connor, W.T., Drew, K.L. and Ungerstedt, U. 1989. Differences in dopamine release and metabolism in rat striatal subregions following acute clozapine using in vivo microdialysis. Neurosci. Lett. 98:211-216.

P7. Drew, K.L., O’Connor, W.T., Kehr, J. and Ungerstedt, U. 1989. Characterization of -aminobutyric acid and dopamine overflow following acute implantation of a microdialysis probe. Life Sci. 45(14):1307-1317.

P8. Drew, K.L. and Glick, S.D., 1990. Role of D-1 and D-2 receptor stimulation in sensitization to amphetamine-induced circling behavior and in expression and extinction of the Pavlovian conditioned response. Psychopharmacology. 101:465-471.

P9. Drew, K.L., O’Connor, W.T., Kehr, J. and Ungerstedt, U. 1990. Regional specific effects of clozapine and haloperidol on GABA and dopamine release in rat basal ganglia. Eur. J. Pharm. 187(3):385-397.

P10. Osborne, P.G., O’Connor, W.T., Drew, K.L. and Ungerstedt, U. 1990. An in vivo microdialysis characterization of extracellular dopamine and GABA in dorsolateral striatum of awake freely moving and halothane anesthetized rats. J. Neurosci. Methods. 34:99-105.

P11. Drew, K.L. and Ungerstedt, U. 1991. Pergolide presynaptically inhibits calcium-stimulated release of -aminobutyric acid from rat dorsolateral striatum. J. Neurochem. 57:1927-1930.

P12. O'Connor, W.T., Drew, K.L. and Ungerstedt, U., 1995, Differential cholinergic regulation of dopamine release in the dorsal and ventral neostriatum of the rat. An in vivo microdialysis study. J. Neurosci., 15(12):8353-8361.

P13. Drew, K.L., Fitka T. and Hu, Y. and Ungerstedt, U. 1997, Non-exocytotic -aminobutyric acid efflux in rat striatum inhibits gnawing. Life Sciences, 61(16):1593-1601.

P14. Clapp-Lilly K.L., Roberts R.C., Duffy L.K., Irons K.P., Hu Y., Drew K.L., 1999, An Ultrastructural analysis of tissue surrounding a microdialysis probe. J. Neurosci. Methods, 90(2), 129-142.

P15. Drew, K.L., Osborne, P.G., Frerichs, K.U., Hu, Y., Koren, R.E. Hallenbeck J.M. and Rice, M.E., 1999, Ascorbate and glutathione regulation in hibernating ground squirrels. Brain Research, 851(1-2), 1-8.

P16. Osborne, P.G., Hu, Y., Covey D.N., Barnes, B.M., Katz, Z., and Drew, K.L., 1999, Determination of striatal extracellular -aminobutyric acid in non-hibernating and

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hibernating arctic ground squirrels using quantitative microdialysis. Brain Research, 839, 1-6.

P17. Toien, O., Drew K.L. Chao, M.L., and Rice M.E., 2001, Ascorbate dynamics and oxygen consumption during arousal from hibernation in Arctic ground squirrels. American Journal of Physiology, 281, R572-R583

P18. Zhou, F., Zhu X., Castellani R.J., Stimmelmayr R., Perry G., Smith M.A. and Drew K.L., 2001, Hibernation, a Model of Neuroprotection. American Journal of Pathology, 158, 2145-2151.

P19. Smith MA, Drew KL, Nunomura A, Takeda A, Hirai K, Zhu X, Atwood CS, Raina AK, Rottkamp CA, Sayre LM, Friedland RP, Perry G. Amyloid-, tau alterations and mitochondrial dysfunction in Alzheimer disease: the chickens or the eggs? Neurochem Int. 2002, 40(6), 527-531.

P20. Drew, K.L., Rice, M.E., Kuhn T.B. and Smith M.A., 2001, Neuroprotective adaptations in hibernation: therapeutic implications for ischemia-reperfusion, traumatic brain injury and neurodegenerative diseases. Free Radical Biology and Medicine. 31(5), 563-573

P21. Drew K. L, Tøien Ø., Rivera P..M. Smith M. A. , Perry G. and Rice M. E., 2002, Role of the Antioxidant Ascorbate in Hibernation and Warming from Hibernation. Comparative Physiology and Biochemistry, 133(4):483-92.

P22. Zhou F, Braddock J F, Hu Y, Zhu X, Castellani RJ, Smith MA and Drew KL., 2002, Microbial Origin of Glutamate, Hibernation and Tissue Trauma: An in vivo Microdialysis Study .J. Neuroscience Methods, 119(2), 121-128

P23. Perry G, Taddeo M, Nunomura A, Zhu X, Zenteno-Savin T, Drew KL, Shimohama S, Avila J, Castellani RJ, Smith MA., 2002, Comparative Biology And Pathology Of Oxidative Stress In Alzheimer And Other Neurodegenerative Diseases: Beyond Damage And Response. Comparative Physiology and Biochemistry, 133(4):507-13.

P24. Rice ME, Forman RE, Chen BT, Avshalumov MV, and Drew KL, 2002, Brain antioxidant regulation in mammals and anoxia-tolerant reptiles: balanced for neuroprotection and neuromodulation. Comparative Physiology and Biochemistry, 133(4):515-25.

P25. Clapp-Lilly KL, Smith MA, Perry G, Harris PL, Zhu X, Drew KL, Duffy LK., 2002, Melatonin exhibits antioxidant properties in a mouse brain slice model of excitotoxicity. Int J Circumpolar Health. 61(1):32-40.

P26. Stimmelmayr R, Drew KL, White RG, 2002, The effect of chronic insulin treatment on body mass , body composition, daily food intake and meal patterns in reindeer fed a concentrate diet during early winter. Comp Biochem Physiol B Biochem Mol Biol 133(2):201

P27. Castellani R, Hirai K, Aliev G, Drew KL, Nunomura A, Takeda A, Cash AD, Obrenovich ME, Perry G, Smith MA, 2002.Role of mitochondrial dysfunction in Alzheimer's disease. J Neurosci Res. 70(3):357-60.

P28. Zhao H, Bucci D, Weltzin M, Drew KL., 2004, Effects of aversive stimuli on learning and memory in wild caught Arctic ground Squirrels. Behav. Brain Res., 151(1-2):219-224

P29. Ma YL, Rice ME, Chao ML, Rivera PM, Zhao HW, Ross AP, Zhu X, Smith MA, Drew KL, 2004, Ascorbate Distribution during Hibernation is Independent of Ascorbate Redox State. Free Radical Biology and Medicine, 37(4):511-20.

P30. Drew KL, Pehek EA, Rasley BT, Ma YL, Green TK, 2004, Sampling Glutamate and GABA with Microdialysis: Suggestions on how to get the Dialysis Membrane Closer to the Synapse. J. Neuroscience Methods, 140 (1-2): 127-131.

P31. Drew KL, Harris MB, LaManna JC, Smith MA, Zhu XW, Ma YL, 2004, Hypoxia tolerance in mammalian heterotherms. J. Exp. Biol., 207:3155-62.

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P32. McGill, CM, Swearingen KE, Drew, KL, Rasley BT, Green TK, 2005 Reaction of Napthalene-2,3-dialdehyde with Cyanide; A Unique Oxidative Condensation Product. Journal of Heterocyclic Chemistry, 42(4), 475-481.

P33. Zhu X, Smith MA, Perry G, Wang Y, Ross AP, Zhao HW, LaManna JC, Drew KL, 2005, The MAPK’s Are Differentially Modulated in AGS during Hibernation. J. Neuroscience Research, 80(6):862-8.

P34. Ma YL, Zhu X, Rivera PM, Toien O, Barnes BM, LaManna JC, Smith MA, Drew KL, 2005, Cellular and physiological stress in hibernation and arousal, Am. J. Physiol., 289(5):R1297-306

P35. Weltzin MM, Zhao HW, Drew KL, Bucci D, 2006, Arousal from Hibernation Alters Contextual Learning and Memory. Behavioral Brain Research, 167(1):128-33

P36. Ross AP, Christian SL, Zhao HW and Drew KL, 2006, Persistent tolerance to oxygen and nutrient deprivation and N-methyl-D-aspartate in cultured hippocampal slices from hibernating Arctic ground squirrel. J. Cerebral Blood Flow and Metabolism, 26(9):1148-56.

P37. Dave KR, Prado R, Raval AP, Drew KL, Perez-Pinzon MA, 2006, The Arctic ground squirrel brain is resistant to injury from cardiac arrest during euthermia, Stroke, 37(5):1261-5.

P38. Zhao H, Ross AP, Christian SL, Buchholz JN, Drew KL,. 2006, Decreased NR1 phosphorylation and decreased NMDAR function in hibernating Arctic ground squirrels. J. Neurosci. Res., 84(2), 291-298.

P39. Ross AP, Drew KL, 2006, Potential for discovery of neuroprotective factors in serum and Tissue Isolated from Hibernating Species. Mini Reviews in Medicinal Chemistry, 6, 875-884. PMID: 17097266

P40. Zhao H, Castillo MR, Christian SL, Bult-Ito A, Drew KL., 2006, Distribution of NMDA Receptors in the Arctic Ground Squirrel., J. Neurochem. Anat. 32(2-4):196-207

P41. Drew KL, Buck CL, Barnes BM, Christian SL, Rasley BT, Harris MB, 2007, Central nervous system regulation of mammalian hibernation: implications for metabolic suppression and ischemia tolerance. J. Neurochem. 102, 1713–1726. PMID: 17555547

P42. Duffy L, Bult-Ito A, Castillo M, Drew K, Harris M, Kuhn T, Ma Y, Schulte M, Taylor B, van Muelken M. Arctic Peoples and Beyond: research opportunities in neuroscience and behaviour. Int J Circumpolar Health. 2007 Jun;66(3):264-75.

P43. Su B. Wang X, Drew KL, Perry G, Smith MA, Zhu X, 2008, Physiological Regulation of Tau Phosphorylation during Hibernation. J. Neurochem., 105, 2098-2108. PMID: 18284615

P44. Christian, SL, Ross AP, Zhao, HW, Kristenson H, Zhan X, Rasley BT, Bickler PE, Drew KL Arctic ground squirrel (Spermophilus parryii) hippocampal neurons tolerate prolonged oxygen glucose deprivation and maintain baseline ERK1/2 and JNK activation despite drastic ATP loss., 2008, J. Cerebral Blood Flow & Metabolism, 28(7):1307-19. PMID: 18398417

P45. Chen, C. Drew K.L. Droplet-based Microdialysis – Concept, Theory, and Design Consideration, 2008, J. of Chromatography. A, 1209(1-2):29-36. PMID: 18814875

P46. Kirschner DL, Wilson AL, Drew KL, Green TK, 2009, Simultaneous efflux of endogenous D-ser and L-glu from single acute hippocampus slices during oxygen glucose deprivation. J. Neurosci. Res., May 12. [Epub ahead of print]; 87(12):2812-20. PMID: 19437552

P47. Orr AL, Lohse LA, Drew KL, Hermes-Lima MH, 2009, Physiological oxidative stress after arousal from hibernation in Arctic ground squirrel. Comp Biochem Physiol A Mol Integr Physiol. 153(2):213-21, PMID: 19233307

P48. Dave KR, Anthony Defazio R, Raval AP, Dashkin O, Saul I, Iceman KE, Perez-Pinzon MA, Drew KL., 2009, Protein kinase C epsilon activation delays neuronal depolarization during

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cardiac arrest in the euthermic arctic ground squirrel. J Neurochem. 2009 May 30. [Epub ahead of print]; 110(4):1170-9. PMID: 19493168

P49. Jinka TR, Carlson ZA, Moore JT, Drew KL. 2010, Altered thermoregulation via sensitization of A1 adenosine receptors in dietary-restricted rats. Psychopharmacology (Berl). 209(3):217-24. Epub 2010 Feb 26. PMID:20186398

P50. Drew KL, McGee RC, Wells MS, Kelleher-Andersson JA, 2011. Growth and differentiation of adult hippocampal arctic ground squirrel neural stem cells J Vis Exp 47: e2199 http://www.jove.com/index/details.stp?ID=2199 doi: 10.3791/2199 (2011) http://www.jove.com/resources/php/frontpagearticles.php?id=2199. PMID: 21248701

P51. Jinka TR, Toien O, and Drew KL, 2011, Season primes the brain in an arctic hibernator to facilitate entrance into torpor mediated by adenosine A1 receptors. J. Neurosci., 31(30):10752-8. PMID: 21795527

P52. Dave KR, Christian SL, Perez-Pinson MA, Drew KL. (2012) Neuroprotection: lessons from hibernators. Comp Biochem Physiol B Biochem Mol Biol. 162(1-3):1-9. Epub 2012 Feb 3. PMID: 22326449

P53. Jinka TR, Rasley BT, Drew KL (2012). Inhibition of NMDA type glutamate receptors induces arousal from torpor in hibernating arctic ground squirrels. Journal of Neurochemistry, 162(1-3):1-9. Epub 2012 Feb 3. PMID:22697356

P54. Olson JM, Jinka TR, Larson LK, Danielson JJ, Moore JT, Carpluck J, Drew KL (2013) circannual rhythm in body temperature, torpor, and sensitivity to A1 adenosine receptor agonist in arctic ground squirrels. J. Biological Rhythms, 28(3), 201-207. PMID:23735499

P55. Drew KL (2013) Raising the ‘Dead’ – Reperfusion from torpor. J. Exp. Biol., 216(Pt 6): 927-9. PMID: 23447661.

P56. Bogren LK, Olson JM, Carpluk J, Moore JM, Drew KL. Resistance to systemic inflammation and multi organ damage after global ischemia/reperfusion in the arctic ground squirrel. PLoS One. 2014 Apr 11;9(4):e94225. doi: 10.1371/journal.pone.0094225. Collection 2014. PubMed PMID: 24728042; PubMed Central PMCID: PMC3984146.

P57. Christian SL, Roe T, Rasley BT, Moore JT, Harris MB, Drew KL (2014) Habituation of arctic ground squirrels (Urocitellus parryii) to handling and movement during torpor to prevent artificial arousal. Front. in Physiol. 5:174-180. doi: 10.3389/fphys.2014.00174. eCollection 2014. PubMed PMID: 24847278; PubMed Central PMCID: PMC4023073.

P58. Bogren LK, Murphy CJ, Johnston EL, Sinha N, Serkova NJ, Drew KL. 1H-NMR metabolomic biomarkers of poor outcome after hemorrhagic shock are absent in hibernators. PLoS One. 2014 Sep 11;9(9):e107493. doi: 10.1371/journal.pone.0107493. eCollection 2014. PubMed PMID: 25211248; PubMed Central PMCID: PMC4161479.

P59. Combs VC, Crispell HD, Drew KL D-cycloserine activation (DCS) of N-methyl-D-aspartate receptors (NMDAR) 24 & 48hr after asphyxial cardiac arrest (ACA) has no effect on hippocampal CA1 neuropathology. J. Cerebral Blood Flow & Metabol., 34(10), 135. doi: 0.1038/jcbfm.2014.135. Epub 2014 Aug 6. PubMed PMID: 25099755; PubMed Central PMCID: PMC4269731.

P60. Drew KL, Colescott P, 2014, Pot or not? Alaska Med., 55:3-6. PMID: 26043489.P61. Larson J, Drew KL, Folkow LP, Milton SL, Park TJ. 2014, No oxygen? No problem!

Intrinsic brain tolerance to hypoxia in vertebrates. J Exp Biol., 1;217(Pt 7):1024-39. doi: 10.1242/jeb.085381. Review. PubMed PMID: 24671961; PubMed Central PMCID: PMC3966918.

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P62. Jinka TR, Combs V, Drew KL. Translating drug-induced hibernation to therapeutic hypothermia. ACS Chem Neurosci. 2015 Jun 17;6(6):899-904. doi: 10.1021/acschemneuro.5b00056. Epub 2015 Apr 8.PMID:25812681

P63. Drew KL, Romanovsky AA, Stephen TK, Tupone D, Williams RH. Future approaches to therapeutic hypothermia: a symposium report. Temperature (Austin). 2015 Apr 23;2(2):168-71. doi: 10.4161/23328940.2014.976512. eCollection 2015 Apr-Jun. PubMed PMID: 27227020; PubMed Central PMCID: PMC4843898.

P64. Drew KL, Wells M, McGee R, Ross AP, Kelleher-Andersson J, Arctic ground squirrel neuronal progenitor cells resist oxygen and glucose deprivation-induced death. World Journal of Biological Chemistry, World J Biol Chem. 2016 Feb 26;7(1):168-77. doi: 10.4331/wjbc.v7.i1.168.

P65. Bogren LK, Johnston EL, Barati Z, Martin PA, Wojda SJ, Van Tets IG, LeBlanc AD, Donahue SW, Drew KL. The effects of hibernation and forced disuse (neurectomy) on bone properties in arctic ground squirrels. Physiol Rep. 2016 May;4(10). pii: e12771. doi: 10.14814/phy2.12771. PubMed PMID: 27225624; PubMed Central PMCID: PMC4886160.

P66. Quinones QJ, Zhang Z, Ma Q, Smith MP, Soderblom E, Moseley MA, Bain J, Newgard CB, Muehlbauer MJ, Hirschey M, Drew KL, Barnes BM, Podgoreanu MV. Proteomic Profiling Reveals Adaptive Responses to Surgical Myocardial Ischemia-Reperfusion in Hibernating Arctic Ground Squirrels Compared to Rats. Anesthesiology. 2016 Jun;124(6):1296-310. doi: 10.1097/ALN.0000000000001113. PubMed [citation] PMID: 27187119, PMCID: PMC4874524

P67. Drew KL, Frare C, Rice SA. Neural Signaling Metabolites May Modulate Energy Use in Hibernation. Neurochem Res. 2017 Jan;42(1):141-150. doi:10.1007/s11064-016-2109-4. PubMed PMID: 27878659; PubMed Central PMCID:PMC5284051.

P68. Bhowmick S, Moore JT, Kirschner DL, Curry MC, Westbrook EG, Rasley BT, DrewKL. Acidotoxicity via ASIC1a Mediates Cell Death during Oxygen Glucose Deprivation and Abolishes Excitotoxicity. ACS Chem Neurosci. 2017 Jun 21;8(6):1204-1212. doi: 10.1021/acschemneuro.6b00355. Epub 2017 Mar 1. PubMed PMID: 28117962.

P69. Bhowmick S, Moore JT, Kirschner DL, Drew KL, Arctic ground squirrel hippocampus tolerates oxygen glucose deprivation independent of hibernaotin season even when not hibernating after ATP depletion, acidosis and glutamate efflux. J Neurochem. 2017 Jul;142(1):160-170. doi: 10.1111/jnc.13996. Epub 2017 May 24. PubMed PMID: 28222226; PubMed Central PMCID: PMC5479730.

P70. Drew KL, Rice SA, Frare C, Metabolic pools of neural signaling molecules may modulate energy balance in hibernation, Neurochemical Research, Neurochem Res. 2017 Jan;42(1):141-150. doi: 10.1007/s11064-016-2109-4. Epub 2016 Nov 23

P71. Bailey IR, Laughlin B, Moore LA, Bogren LK, Barati Z, Drew KL, Optimization of thermolytic response to A1 adenosine receptor agonists in rats. J Pharmacol Exp Ther. 2017 Sep;362(3):424-430.

P72. Bhowmick, S and Drew KL, Arctic Ground Squirrel resist peroxynitrite-mediated cell death in response to oxygen glucose deprivation, Free Radic Biol Med., 2017 Dec;113:203-211

P73. Laughlin B, Bailey I, Rice S, Barati Z, Bogren L, Drew K. Precise control of target temperature using N6-cyclohexyladenosine and real time control of surface temperature, Therapeutic hypothermia and temperature management. 2018 Feb 26.

Papers Submitted or in Preparation:

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Book Chapters/Book Reviews/Letters to Editor:C1.Shapiro, R.M., Drew, K.L. and Glick, S.D. 1988, Brain asymmetry, animal. In: Encyclopedia

of Neuroscience. Birkhauser Boston, Inc., Cambridge, Mass. C2.O’Connor, W.T., Drew, K.L., Carlsson, H. and Ungerstedt, U., 1992, Neostigmine enhances

haloperidol-induced increases in acetylcholine release from rat striatal subregions: An in vivo microdialysis study. Current Separations. 10(3):115-116,

C3.Bell M. Drew, K.L., Smith M.A. and Hallenbeck, J.M., 2002, Ischemic tolerance in the Brain – Models and Mechanisms. In Cell and Molecular Responses to Stress. KB Storey and JM Storey (Eds.). Elsevier Press, pp 1-12.

C4.Drew KL, Zhou F, Zhu X, Castellani RJ, Smith MA (2004) Protection from traumatic brain injury during hibernation. Life in the cold, BM Barnes (Ed).

C5.Hermes-Lima M, Ramos-Vasconcelos GR, Cardoso LA, Orr AL, Rivera PM, Drew KL (2004), Animal adaptability to oxidative stress – gastropod estivation and mammalian hibernation. Life in the Cold, BM Barnes (Ed).

C6.Drew KL, Christian SL, Jinka TR, Hollen L, Dehn J, 2009, “Natural” tolerance in hibernators: Can we learn from physiological and preconditioning against ischemic or hypoxic brain? In Ischemic Tolerance of the Brain. BJ Schaller (Ed.), Research Signpost, Kerala, India, pp 1-44.

C7.Chen C-f., Rasley, BT, Warlick BPE, Green TK, Swearingen KE, Drew KL (2013) Review of microdialysis and advances for sampling synaptic and extrasynaptic pools. In, Giuseppe Di Giovanni and Vincenzo Di Matteo (eds.), Microdialysis Techniques in Neuroscience, Neuromethods, vol. 75, pp. 63-88.

C8.Jinka TR, Barrickman ZA, Bogren LK, Lee TM, Olson JM, Richter MM, Salli BM, Stevenson TJ, Tøien Ø, Buck CL, Drew KL (2012) Potential mechanisms of metabolic suppression downstream of central A1AR activation during onset of torpor. In: Ruf T, Bieber C, Arnold W, Millesi E (eds). Living in a seasonal world: thermoregulatory and metabolic adaptations. Springer, Heidelberg.

C9. Drew KL, Jinka TR (2012) The bioenergetic network of adenosine in hibernation, sleep and thermoregulation. In: Adenosine: a Key Link between Metabolism and CNS Activity. Masino SA and Boison D (Eds), Springer, pp. 363-376.

C10. Drew KL, Zuckerman JA, Shenk PE, Bogren LK, Jinka TR, Moore JT (2012) Hibernation: a natural model of tolerance to cerebral ischemia/reperfusion. In Innate Neuroprotection for Stroke, J Gidday, M Perez-Pinzon, J Zhang (Eds.) Springer, New York, NY, 2013 .

AbstractsA1. Drew, K.L., Lyon, R.A., Tietler, M. and Glick, S.D. Right>left asymmetry in D-2 binding

in female rat striatum. Neurosci. Abstr. 1985. 11:870.A2. Drew, K.L. and Glick, S.D. Classical conditioning of amphetamine-induced rotation in

unlesioned rats. Neurosci. Abstr. 1986. 12:1535.A3. Drew, K.L. and Glick, S.D. Environment dependent sensitization to amphetamine-induced

circling behavior in unlesioned female rats. Neurosci. Abstr. 1987.A4. Baird, J.L., Glick, S.D., Carlson, J.N. and Drew, K.L. Epinephrine in rat corpus striatum:

In vivo microdialysis and HPLC analysis. Neurosci. Abstr. 1987.A5. Glick, S.D., Carlson, J.N., Baird, J.L. and Drew, K.L. Asymmetry in striatal dopamine

release and metabolism: Bilateral in vivo dialysis in normal rats. Neurosci. Abstr. 1987.A6. Drew, K.L., O’Connor W.T., Kehr, J. and Ungerstedt, U. GABA overflow in rat globus

pallidus following neuroleptic and apomorphine administration measured by in vivo microdialysis. Neurosci. Abstr. 1988.

22


A7. O’Connor, W.T., Osborne, P.G., Drew, K.L. and Ungerstedt, U. An in vivo microdialysis characterization of extracellular dopamine and GABA in dorsolateral striatum of halothane anaesthetized and conscious rats. The fourth meeting on electrochemical detection, HPLC and in vivo monitoring in the biosciences, Nottingham, U.K. 1989.

A8. O’Connor, W.T., Osborne, P.G., Drew, K.L., Reid, M.S., Tanganelli, S., Fuxe, K. and Ungerstedt, U. Dopamine and neurotensin modulation of GABA release in the striatum. The fourth Nordic neuroscience meeting, , Sweden. 1989.

A9. Drew, K.L., O’Connor, W.T., Kehr, J. and Ungerstedt, U. Regional specific effects of clozapine and haloperidol on GABA release in rat basal ganglia. Neurosci. Abstr. 109.15. 1990.

A10. O’Connor, W.T., Drew, K.L. and Ungerstedt, U. Neostigmine enhances the increase in acetylcholine release following haloperidol in rat striatal subregions. International symposium on microdialysis and allied analytical techniques, Indianapolis, Indiana. 1991.

A11. Drew, K.L. and Ungerstedt, U. D2 receptor stimulation presynaptically inhibits calcium stimulated release of -aminobutyric acid from rat dorsolateral striatum. Monitoring molecules in neuroscience. Proceedings of the 5th International Conference on In Vivo Methods. Noordwijkerhout, The Netherlands. 1991. pg 102.

A12. O’Connor, W.T., Herrera-Marschitz, M., Linderfors, N., Osborne, P.G., Drew, K.L., Reid, M. and Ungerstedt, U. Dopamine-GABA interactions in the neostriatum. Monitoring molecules in neuroscience. Proceedings of the 5th International Conference on In Vivo Methods. Noordwijkerhout, The Netherlands. 1991. pg 93.

A13. Drew, K.L. and Ungerstedt, U. 1992. SKF 89976A increases extracellular GABA in rat dorsolateral striatum in vivo. Neurosci. Abstr., 421.3.

A14. Drew, K.L., Fitka, T. and Hu, Y. 1994. Behavioral effects of microinjections of 3-mercaptopropionic acid in rat striatum using in vivo microdialysis to sample -aminobutyric Acid (GABA). Society for Neurosci. Abstr., 379.9.

A15. Hu, Y., Irons, K. and Drew, K.L. 1995. Electron microscopy of brain tissue surrounding a microdialysis probe in rat striatum. American Association for the Advancement of Science 46th Arctic Division Science Conference, Fairbanks, Alaska.

A16. Jackson, D., Hu, Y., and Drew, K.L., 1996, GABA release from inferior colliculus in awake freely moving rats. Society for Neurosci. Abstr., 350.5.

A17. Drew, K.L., Hu, Y., Koren, R.E., and Rice, M.E., 1997, Stroke therapies from hibernating squirrels. Society for Neurosci. Abstr., 743.7.

A18. Osborne P.G. and Drew K.L., 1997, Arctic ground squirrels - from parkas to post stroke therapy; a medical resource comes to light. AAAS, 48th Arctic Division Science Conference, Valdez, AK.

A19. Drew K.L., Osborne P.G., Hu Y., Covey D.N., Katz, Z. Duffy, L.K. and Barnes B.M., 1998, Determination of extracellular -aminobutyric acid during homeothermy and hibernation in striatum of arctic ground squirrels using quantitative microdialysis. American Society for Neurochemistry, March 1998.

A20. Clapp K.L., Roberts R.C., Duffy L.K., Hu Y., Irons K. and Drew K.L., 1998, Ultrastructural analysis of microdialysis-induced trauma in rat brain. American Society for Neurochemistry, March 1998.

A21. Hu Y., Osborne P.G., Stimmelmayr R. and Drew K.L., 1998, Hibernation: A model of tolerance to brain trauma. Society for Neurosi. Abstr., 676.13.

A22. Clapp K.L., Roberts R.C., Hu Y., Crosby K.M., Duffy L.K. and Drew K.L., 1998, Disruption of ultrastructure in rat striatum following microdialysis. Society for Neurosi. Abstr., 674.1.

23


A23. Drew K.L., Rice M.E., Frerichs K.U. and Hallenbeck J.M., 1999, Stroke therapies from hibernating squirrels, Winter Conference on Brain Research, Snowmass, CO, Jan 23-30.

A24. Drew K.L., Clapp-Lilly K.L, Roberts R.C., Duffy L.K., Irons K.P., and Hu Y., 1999, An Ultrastructural Analysis of Tissue Surrounding a Microdialysis Probe. 8th International Conference on In Vivo Methods: “Monitoring Molecules in Neuroscience.” Stony Brook, NY, June 19-23.

A25. Drew K.L., Osborne P.G., Hu Y., Stimmelmayr R., Barnes B.M., 1999, Hibernation: a natural model of tolerance to brain trauma. Hibernation and Adaptations to the Cold, Estes Park, CO, May 20-22.

A26. Drew K.L., Osborne P.G., Hu Y., Stimmelmayr R., Barnes B.M., 1999, Hibernation and Tolerance to Brain Trauma, 50th Arctic Science Conference, Science in the North: 50 Years of Change. Denali National Park and Preserve, Alaska, Sept. 19-22.

A27. Tøien, Ø. Rice, M.E. Barnes, B. M. and Drew, K.L. 1999, Plasma ascorbate and oxygen consumption during rewarming from hibernation in arctic ground squirrels. Society for Neurosi. Abstr., 736.21

A28. Richardson, C.F., Drew K.L., and Kuhn, T.B., 1999, Reduced Ca2+ changes in response to depolarizing stimuli in neurons during hibernation in arctic ground squirrels. Society for Neurosi. Abstr., 841.7

A29. Zhou, F. Hu, Y., Braddock, J.F. and Drew, K.L., 2000, Microbial origin of glutamate in microdialysis studies of hibernating ground squirrels. Society for Neurosi. Abstr., 188.2

A30. K.L.Drew, F. Zhou, Y. Hu, J.F. Braddock, X. Zhu, R. Castellani, M.A Smith, Microdialysis, tissue trauma and glutamate in hibernating brains. 9th Annual Meeting On In Vivo Methods For Monitoring Molecules In Neuroscience. Dublin, June 2001.

A31. Drew K.L., F. Zhou, X. Zhu, R. Castellani, M.A Smith, Hibernation, a model of neuroprotection. Winter Conference on Brain Research, Steamboat Springs, Colorado, Jan. 2001.

A32. Zhou F., X. Zhu, R.J. Castellani, R.S. Stimmelmayr, G.Perry, M.A. Smith and K.L. Drew, Hibernation, a model of neuroprotection. Cell Death and Aging, Miami Beach, Florida, Feb. 2001.

A33. Drew K.L., Rivera, P.M. Ross A.P. Corrick R. M., Tøien Ø. Zhu X. Chao M.L. Smith M.A. Rice M.E., Antioxidant effects of ascorbate during rewarming from hibernation in arctic ground squirrels. Society for Neurosi. Abstr. San Diego, CA, Nov. 2001

A34. K.L.Drew, F. Zhou, Y. Hu, J.F. Braddock, X. Zhu, R. Castellani, M.A Smith, Microdialysis, tissue trauma and glutamate in hibernating brains. Alaskan Summer Neuroscience Conference, Fairbanks, AK July 29, 2001

A35. Drew KL, Ma Y, Rivera P, Cozad K, Toien O, Arterial Blood Gases During Hibernation in the Arctic Ground Squirrel, Stroke - Molecular, Cellular, Pharmacological and Development of New Therapeutics, March 9 - March 14, 2002, Taos, New Mexico.

A36. Ross A and Drew KL, Neuroprotection during Hypoxia in the Arctic Ground Squirrel Molecular, Cellular, Pharmacological and Development of New Therapeutics, March 9 - March 14, 2002, Taos, New Mexico.

A37. Richardson C, Drew KL, Kuhn TB, Decreased Rise in Free Intracellular Ca2+in Synaptosomes and Slices from Hibernating Arctic Ground Squirrels. 2nd Annual Conference of Specialized Programs in Neuroscience, May 15-17, 2002, San Antonio, Texas

A38. Cozad K, Ma Y, Rivera PM, Zhao H, Drew KL, Mechanisms of Hypoxia Tolerance Compared with Hibernation 2nd Annual Conference of Specialized Programs in Neuroscience, May 15-17, 2002, San Antonio, Texas

A39. Drew KL, Ma Y, Rivera PM, Cozad K, Toien O, Zhu X, Smith MA. Exit from Torpor: A

24


Natural Model of Tolerance to Reperfusion 2nd Annual Conference of Specialized Programs in Neuroscience, May 15-17, 2002, San Antonio, Texas

A40. Rivera PM, Zhu X, Smith MA, Rice ME, Drew KL. Study of Oxidative Stress in CA-1 Region of Hippocampus during Euthermia, Torpor and Arousal from Torpor in Arctic Ground Squirrels (Spermophilus perryii) 2nd Annual Conference of Specialized Programs in Neuroscience, May 15-17, 2002, San Antonio, Texas

A41. Ross A, Drew KL NMDA Tolerance in Organotypic Hippocampal Slices : A Hibernating Versus Non – Hibernating Species 2nd Annual Conference of Specialized Programs in Neuroscience, May 15-17, 2002, San Antonio, Texas

A42. Zhao H, Weltzin M, Drew KL, Effects of Hibernation on Retention of an Active Avoidance Task 2nd Annual Conference of Specialized Programs in Neuroscience, May 15-17, 2002, San Antonio, Texas

A43. Cozad K, Ma Y, Rivera PM, Zhao H, Drew KL, Mechanisms of Hypoxia Tolerance Compared with Hibernation. Alaskan Summer Neuroscience Conference, July 14-15, 2002, Fairbanks, AK

A44. Drew KL, Ma Y, Rivera PM, Cozad K, Toien O, Zhu X, Smith MA. Hibernation: A Natural Model of Tolerance to Reperfusion Alaskan Summer Neuroscience Conference, July 14-15, 2002, Fairbanks, AK

A45. Rivera PM, Zhu X, Smith MA, Rice ME, Drew KL Study of Oxidative Stress in CA1 Region of Hippocampus in Arctic Ground Squirrels (Spermophilus perryii). Alaskan Summer Neuroscience Conference, July 14-15, 2002, Fairbanks, AK

A46. Ross A, Drew KL NMDA Tolerance in Organotypic Hippocampal Slices. Alaskan Summer Neuroscience Conference, July 14-15, 2002, Fairbanks, AK

A47. Zhao H, Weltzin M, Drew KL, Effects of Hibernation on Retention of an Active Avoidance Task. Alaskan Summer Neuroscience Conference, July 14-15, 2002, Fairbanks, AK

A48. Ma Y, Rivera P, Kelliher A, Smith MA, Zhu X, Rice ME, Drew KL. Fate of Ascorbate During Hibernation in Arctic Ground Squirrels. Society for Neuroscience, November 2-7, 2002, Orlando, Florida.

A49. Zhao H, Weltzin M, Bucci D, Drew KL, Effects of Hibernation on Retention of an Active Avoidance Task. Society for Neuroscience, November 2-7, 2002, Orlando, Florida.

A50. Drew KL, Ma Y, Rivera P, Cozad K, Toien O, Zhu X, LaManna J, Smith MA. Arousal from Hibernation: A Natural model of Tolerance to Reperfusion. Society for Neuroscience, November 2-7, 2002, Orlando, Florida.

A51. Rivera P.M. Ma Y.L. Zhu X. Ross A, Castellani R, Smith MA, Rice ME and Drew KL (2003) Study of oxidative stress in CA1 neurons and liver during euthermia, torpor and arousal from torpor in arctic ground squirrels (spermophilus parryii) 3rd Annual Conference of Specialized Programs in Neuroscience, May 28-30, 2003, Honolulu, Hawaii

A52. Green TK, McGill CG, Swearingen KE, Rasley BT, Drew KL, Characterization of Side Products from NDA/NaCN on-column derivatization of amino acid neurotransmitters. Proceedings of the 10th International Conference on In Vivo Methods, J. Kehr, K. Fuxe, U. Ungerstedt, T. Svensson, eds. Karolinska Institute, 2003, p 478.

A53. Rasley BT, Drew KL, Dick E, Swearingen KE, Green TK, In Vivo Monitoring of Glutamate in Hibernating Ground Squirrels: Construction of an On-line Microdialsysis/Capillary Electrophoresis/Laser-induced Fluorescence Instrument. Proceedings of the 10th International Conference on In Vivo Methods, J. Kehr, K. Fuxe, U. Ungerstedt, T. Svensson, eds. Karolinska Institute Stockholm 2003, p 481.

A54. Drew KL, Pehek EA, Rasley BT, Ma Y, Green TK, Sampling Glutamate and GABA with Microdialysis: How to get the Membrane Closer to the Synapse? Proceedings of the 10th

25


International Conference on In Vivo Methods, J. Kehr, K. Fuxe, U. Ungerstedt, T. Svensson, eds. Karolinska Institute Stockholm 2003,

A55. Zhao, H, Castillo MR, Bult-Ito, A, Drew KL, Distribution of NMDA receptors in Arctic ground squirrels. Society for Neuroscience, November 7-13, 2003, New Orleans, LA

A56. Ma YL, Rivera P, Wu SF, Drew KL, Enhanced plasma ascorbate stability in hibernation. Society for Neuroscience, November 7-13, 2003, New Orleans, LA

A57. Weltzin MM, Bucci DJ, Zhao H, Drew KL (2003) Hibernation, Learning and Memory, Cell Biology of the Neuron, November 7, 2003, New Orleans, LA.

A58. Zhao HW, Ross AP, Buchholz JN, Drew KL, Intracellular [Ca2+] in Cultured Hippocampal Slices of Hibernating Arctic Ground Squirrel. American Society for Neurochemistry, New York, NY, August 2004

A59. Ross, AP, Christian, SL, Zhao, HW, and KL Drew, Excitotoxic Tolerance in Hippocampal Slices from a Hibernating Species, Society For Neuroscience 34th Annual Meeting, San Diego, CA, Oct.23-27, 2004

A60. Ma YL, Cozad KD, Rivera PM, Zhao, HW, Drew KL (2004) Differences in hypoxia tolerance between AGS and rats. Society for Neurosci

A61. Dave KR, Prado R, Raval AP, Drew KL, Perez-Pinzon MA (2004) Remarkable ischemic tolerance by the Arctic ground squirrel against cardiac arrest during euthermia. Society for Neurosci. abstract.

A62. Ross AP, Drew KL (2004) Neuroprotection from excitotoxic insult in hippocampal slices from a hibernating species, arctic ground squirrel. 10th International Symposium on Pharmacology of Cerebral Ischemia Marburg, Germany, July 25-28, 2004

A63. Zhao H, Ross AP, Buchholz JN, Drew KL. (2004) Intracellular [Ca2+] in Cultured Hippocampal Slices of Hibernating Arctic Ground Squirrel. Society For Neuroscience 34th Annual Meeting, Oct. 22-26, 2004, San Diego, CA.

A64. Zhao H, Ross AP, Christian SL, Buchholz JN, Drew KL Suppression of NMDA receptor function in hibernating Arctic ground squirrels 36th American Society for Neurochemistry annual meeting, June.24-29, 2005, Madison. WI.

A65. Drew KL, Dave KR, Prado R, Raval AP, and Perez-Pinzon MA, (2006) Euthermic Arctic ground squirrels tolerate global cerebral ischemia. American Society for Neurochemistry, March 11-15, Portland, Oregon. J. Neurochem., 96(Suppl. 1), 120.

A66. Drew KL, Ross AP, Christian SL, Zhao HW, (2006) Tolerance to oxygen and nutrient deprivation and NMDA in hippocampal slices from hibernating arctic ground squirrel. American Society for Neurochemistry, March 11-15, Portland, Oregon. J. Neurochem., 96(Suppl. 1), 120.

A67. Zhao HW, Castillo MR, Christian SL, Bult-Ito A, Drew KL (2006) Distribution of NMDA receptor NR1 in arctic ground squirrel central nervous system. American Society for Neurochemistry, March 11-15, Portland, Oregon. J. Neurochem., 96(Suppl. 1), 101..

A68. Weltzin MM, Zhao HW, Drew KL, Bucci DJ (2006) Arousal from hibernation alters contextual learning and memory. American Society for Neurochemistry, March 11-15, Portland, Oregon. J. Neurochem., 96(Suppl. 1), 22.

A69. Drew KL, Christian SL, Rasley BT, Dave KR Prado R, Raval AP, Perez-Pinzon MA, Neuroprotection in Hibernation and Euthermy. (2006) 5th Dutch Endo-Neuro-Psycho meeting Doorwerth, Netherlands

A70. Jinka TR, Drew KL (2006). MK-801 Induces Arousal in Hibernating Arctic Ground Squirrels. Specialized Neuroscience Research Program 6th Annual Meeting, May 30- June 2, Fairbanks, AK.

A71. Green TK, Kirschner DL, Jaramillo M, Drew KL, Rasley BT (2006) Enantioseparation and

26


Stacking of DL-serine by Capillary Electrophoresis and Laser induced Fluorescence Detection. Specialized Neuroscience Research Program 6th Annual Meeting, May 30- June 2, Fairbanks, AK.

A72. Christian SL, Schulenburg B, Kristenson H, Rasley BT, Ross AP, Zhao HW, Drew KL, 2006 The neuroprotective molecular mechanisms used by the Arctic ground squirrel, Spermophilus parryii, to survive oxygen-glucose deprivation Specialized Neuroscience Research Program 6th Annual Meeting, May 30- June 2, Fairbanks, AK.

A73. Jinka TR, Drew KL (2006). MK-801 Induces Arousal in Hibernating Arctic Ground Squirrels. University of Alaska Biomedical Research Conference 2nd Annual Meeting, May 22-23,2006, Anchorage, AK.

A74. Drew KL, Christian SL, Rasley BT, Ross AP, Zhao HW, Dave KR Prado R, Raval AP, Perez-Pinzon MA (2006) Evidence for and Mechanisms of Tolerance to Global Ischemia In Vivo and Oxygen Glucose Deprivation In Vitro in the Arctic Ground Squirrel. 6th Annual Specialized Programs in Neuroscience Research (SNRP) Conference. May 31-June 2, Fairbanks, AK

A75. C.-f. Chen and K. L. Drew, Interstitial Diffusion and Combined Drifting Motion of Brownian Particles Modeling Toward Miniaturization of Microdialysis Probes,6th Annual Specialized Programs in Neuroscience Research (SNRP) Conference, Fairbanks, Alaska, May 31 - June 2, 2006.

A76. C.-f. Chen and K. L. Drew, Interstitial Diffusion and Combined Drifting Motion of Brownian Particles Modeling Toward Miniaturization of Microdialysis Probes, 7th World Congress on Computational Mechanics, Los Angeles, California, July 16 - 22, 2006.

A77. Drew KL, Christian SL, Schulenburg B, Kristenson H, Rasley BT, Ross AP and Zhao HW, 2006, Mechanisms of tolerance to oxygen glucose deprivation in Arctic ground squirrels. Society for Neurosci. Atlanta, GA Oct. 13-18, 2006

A78. Drew KL, Wells MS, Christian SL, and Kelleher-Andersson JA, Tolerance to Oxygen Glucose Deprivation in Differentiated Adult Hippocampal Neuronal Stem Cells Obtained from Arctic Ground Squirrels (Spermophilus parryii). International Stroke Conference, San Francisco, CA, Feb. 7-9, 2007; Stroke, 38(2), 558.

A79. Green TK, Kirschner DL, Jaramillo M, Rasley BT, Drew KL (2006), Analysis of glutamate and D-serine by reverse polarity capillary electrophoresis using highly-charged, sulfated -cyclodextrin. Proceedings of the 11th International Conference on In Vivo Methods. V. Valentini and G. Di Chiara eds., University of Cagliari, Sardinia, Italy.

A80. C.-F. Chen, K. L. Drew, 2007, Droplet based microdialysis and estimates of saturation times. Microscale Bioseparations. Vancouver, B.C. Canada

A81. B. Su, X. Wang, K. Drew, M. A. Smith, G. Perry, X. Zhu, 2006, Physiological regulation of tau phosphorylation during hibernation-the role of o-GlcNAcylation, Program No. 468.23. Society for Neuroscience. Atlanta GA

A82. L. Hollen, J. Dehn, M. Aoki, K. L. Drew, 2006, Heterogeneous warming from arctic ground squirrels during hibernation monitored by forward looking infrared radiometer, Program No. 489.15. Society for Neuroscience. Atlanta GA

A83. Y. Ma, S. Wu, M. Harris, O. Toien, B. Rasley, K. Drew, 2006, Brain oxygen defense during hypoxic exposure in non-sedated, non-anesthetized Arctic ground squirrels Program No. 760.2. Society for Neuroscience. Atlanta GA

A84. A.L. Wilson, J. Moore, I. Kruman, K.L. Drew UCP-2 Increases OGD Tolerance in Euthermic Arctic Ground Squirrels, Spermophilus parryii. International Society for Neurochemistry, Cancun, Mexico, August 19-24, 2007.

A85. Jinka, TR, Toien, O, Rasley, BT., Drew, KL, MK-801 induces arousal from hibernation

27


through peripheral effects. International Society for Neurochemistry, Cancun, Mexico, August 19-24, 2007.

A86. Jinka, T.R., Toien, O., Rasley, B.T., Drew, K.L (2008) MK-801 Induces Arousal from Hibernation through Peripheral Effects. The Society for Integrative & Comparative Biology (SICB) Annual Meeting, San Antonio, Texas, January 2-6, 2008.

A87. Wilson, A.L. Moore, J.M., Drew, K.L., 2008 Spermophilus parryii Tolerate Ionic Shift During Modeled Ischemia, 7th Annual Specialized Programs in Neuroscience Research (SNRP) Conference. New York, NY, August 20-22, 2008

A88. Jinka, T.R., Toien, O.T., Drew K.L. (2008) A1 receptor activation lowers effective temperature set-point and induces torpor in hibernation. 151.10, Society for Neurosci. Washington DC, Nov 15-19, 2008

A89. McGee, R.C., Drew K.L., Wells M.S., Kelleher-Andersson, J.A., (2008) Neurons derived from Arctic ground squirrel neural stem cells tolerate oxygen-glucose deprivation by enhanced capacity for anaerobic metabolism and neurogenesis, 151.13, Society for Neurosci. Washington DC, Nov 15-19, 2008

A90. Kirschner, D.L., Wilson, A.L., Drew, K.L., Green, T.K. (2008) Microperfusion sampling with offline CE-LIF to study D-ser and L-glu dynamics in single acute hippocampus slices, 750.8, Society for Neurosci. Washington DC, Nov 15-19, 2008.

A91. Iceman, K. and Drew, K.L., Arctic ground squirrel cultured hippocampal neuronal stem cells contain NR1 subunit of NMDA receptor and are resistant to excitotoxic NMDA treatment. University of Alaska Biomedical Research Conference. May 14-15, 2009.

A92. Carlson, Z.A., Jinka, T.J., Moore J.T., Drew, K.L. Adenosine A1 receptor mediated drop in body temperature in response to dietary restriction. University of Alaska Biomedical Research Conference. May 14-15, 2009.

A93. Jinka, T.R., Carlson, Z.A., Toien, O., Drew, K.L., Torpor mediated through endogenous adenosine is specific to A1AR in hibernating Arctic ground squirrels. University of Alaska Biomedical Research Conference. May 14-15, 2009.

A94. Moore JT, Kirschner DL, Wetherell KG, Drew KL, Resistance to modeled cerebral ischemia in arctic ground squirrel (Spermophilus parryii) hippocampal slices studied using a novel, microperfusion device, 332.2, Chicago, Oct. 17-21, 2009.

A95. Carlson ZA, Jinka TR, Moore JT, Drew KL, Eu-GTPγS: A non-radioactive approach to assessing G-Protein Coupled Receptor function. Joint 65th Northwest/22nd Rocky Mountain Regional Meeting of the American Chemical Society, NORM/RMRM 2010, Pullman, Wahington, June 20-23, 2010

A96. Jinka TR, Carlson ZA, Moore JT, Drew KL, Altered thermoregulation via sensitization of A1 adenosine receptors in dietary-restricted rats. 40thAnnual Meeting of the Society for Neuroscience, San Diego, CA, November 13 – 17, 2010

A97. Jinka TR, Rasley BT, Drew KL, Inhibition of NMDA Type Glutamate Receptors Induces Arousal from Torpor in Hibernating Arctic Ground Squirrels. Keystone Symposium, Metabolic Responses to Extreme Conditions, Big Sky, Montana , April 1 - 5, 2011.

A98. Jinka TR, Carlson ZA, Moore JT, Drew KL, Altered thermoregulation via sensitization of A1 adenosine receptors in dietary-restricted rats. Keystone Symposium, Metabolic Responses to Extreme Conditions, Big Sky, Montana , April 1 - 5, 2011.

A99. Drew KL Jinka TR, Tøien Ø, Seasonal Sensitization in Purinergic Signaling Permits Adenosine A1 Receptor Activation to Induce Torpor in Hibernating Arctic Ground Squirrels. Keystone Symposium, Metabolic Responses to Extreme Conditions, Big Sky, Montana , April 1 - 5, 2011.

A100. Bogren LK, Olson JM, Carpluk J, Moore JT, Drew KL, Resistance to multi-organ damage

28


after hemorrhagic shock induced ischemia/reperfusion in arctic ground squirrels. Across Societies – Experimental Biology, San Diego, CA April 22, 2012.

A101. Drew KL, Jinka TR, Olson JM, Acclimation to cold ambient temperature in the winter season is necessary for adenosine-induced torpor in arctic ground squirrels. UA Biomedical Research Conference, Fairbanks, AK May 21-23, 2012.

A102. Jinka TR, Pietila M, Bhowmick S, Drew KL, Central A1AR activation does not decrease metabolic rate or improve outcome following cardiac arrest when body temperature is maintained at 37°C. UA Biomedical Research Conference, Fairbanks, AK May 21-23, 2012.

A103. Bhowmick S, Drew KL, Expression of neuroglobin in rats and arctic ground squirrel brain: a comparative study. UA Biomedical Research Conference, Fairbanks, AK May 21-23, 2012.

A104. Bogren LK, Olson JM, Carpluk J, Moore JT, Drew KL, Resistance to multi-organ damage after hemorrhagic shock induced ischemia/reperfusion in arctic ground squirrels. UA Biomedical Research Conference, Fairbanks, AK May 21-23, 2012.

A105. Frare C., Walf A.A., Power J.M., Drew K.L., Frye C.A., Preliminary observations of neurosteroids in hibernation reflect stress and neuroplasticity associated with interbout arousal in the arctic ground squirrel, University of Alaska Biomedical Research Conference, University of Alaska, Anchorage, AK, May 2013.

A106. Drew KL, Combs VM, Jinka TR, Translating drug-induced hibernation to therapeutic hypothermia. Birmingham, UK, 2013, Proc 37th IUPS.

A107. Frare C., Walf A.A., Power J.M., Drew K.L., Frye C.A., Preliminary observations of neurosteroids in hibernation reflect stress and neuroplasticity associated with interbout arousal in the arctic ground squirrel, International Meeting Steroids and Nervous System, Torino, Italy, February 2013.

A108. Frare C, Drew KL, The role of tanycytes in seasonal response to adenosine-induced hibernation. Society for Neuroscience, San Diego, CA Nov. 9-13, 2014.

A109. Power JM, Frare C, Drew KL, Frye CA, Neurosteroids and neuroplasticisty associated with interbout arousal from hibernation in arctic ground squirrel. Society for Neuroscience, San Diego, CA Nov. 9-13, 2014.

A110. Bailey IR, Bogren LK, Drew KL, Targeted temperature management with a novel adenosine agonist. Exp. Biol., San Diego, CA April 26-30, 2014.

A111. Bogren LK, Murphy CJ, Johnston EL, Serkova NJ, Drew KL, 1H-NMR metabolomic biomarkers of poor outcome after hemorrhagic shock are absent in hibernators. Exp. Biol., San Diego, CA April 26-30, 2014.

A112. Bogren LK, Johnston EL, Van Tets IG, LeBlanc AD, Drew KL, Bone density is maintained during forced disuse in hibernators throughout both the active and hibernation seasons. Exp. Biol., San Diego, CA April 26-30, 2014.

A113. Zeinab Barati, Tulasi Jinka, and Kelly Drew, “ECG of Hibernating Arctic Ground Squirrels”, 2014 Arctic Science Conference, Fairbanks, AK, September 27 – 28, 2014

A114. Bhowmick S, Moore J, Drew KL, Ischemic injury monitored with a novel microperfusion device unveils the role of pH in I/R injury. NIH, NIGMS Fifth Biennial National IDeA Symposium of Biomedical Research Excellence (NISBRE) 2014. June 16-18, Washington, DC

A115. Bhowmick S, Drew KL, Neuroprotective role of neuroglobin via targeting nitric oxide signaling pathway. 46th Annual Society for Neurochemistry (ASN) meeting 2015. March 14-18, Atlanta, Georgia

A116. Bailey IR, Bogren LK, Drew KL, Targeted temperature management with full and partial A1 adenosine agonists. NIGMS Fifth Biennial National IDeA Symposium of Biomedical Research Excellence (NISBRE) 2014. June 16-18, Washington, DC

29


A117. Bailey IR, Murphy CJ, Drew KL, Bogren LK, Targeted temperature management with A1 adenosine agonists in conjunction with ambient temperature control in rats. Brain and PET 2015. June 27-30, Vancouver, Canada

A118. Drew KL, Translating Drug-induced hibernation to therapeutic hibernation in Pharmacologically induced hypothermia and clinical implications, Shan Ping Yu (Chair). ASN 2015, Atlanta, GA, March 14-18, 2015

A119. Drew KL, Central nervous system control of hibernation reveals opportunities for human hibernation. Scandinavian Physiological Society meeting, Aarhus, Denmark, Sept. 18-20, 2015.

A120. Drew KL, Translating CNS control of hibernation to non-hibernating species. 9th meeting of the International Society for Autonomic Neuroscience (ISAN 2015), Stresa, Italy, Sept. 26-29, 2015.

A121. Rice, S., Drew, K. "Preliminary Data: Ammonium Acetate Infusion Impact on Arousal via Temperature, Metabolites and Oxygen Consumption " 15th International Hibernation Symposium 2016 (Las Vegas, NV July 31-August 4th, 2016)

A122. Rice, S., Drew, K. "Preliminary Data: Ammonium Acetate Infusion Impact on Arousal via Temperature and Oxygen Consumption Recordings" University of Alaska Biomedical Research Conference 2016 (Fairbanks, AK May 20-21, 2016)

A123. Barati Z, Jinka T, and Drew K. “ECG of Hibernating Arctic Ground Squirrels”, The 2014 Arctic Science Conference, September 27 – 28, 2014, Fairbanks, AK, United States

A124. Dowell K, Laughlin B, Barati Z, and Drew K. “A Study of Bradycardia During N6Cyclohexyladenosine Induced Cooling in Rats”, Hibernation 3.0 Regional Conference, July 03, 2015, Duluth, Minnesota, United States

A125. Drew K, Jinka T, Barati Z, Rice S, Laughlin B, and Bailey I. “Translating CNS control of hibernation to nonhibernating species”, 9th Meeting of the International Society for Autonomic Neuroscience, September 26, 2015, Stresa, Italy

A126. Dowell K, Barati Z, Laughlin B, and Drew K. “Analysis of Cardiac Arrhythmias in N6 CyclohexyladenosineAssisted Cooling of Rats”, 15th International Hibernation Symposium, July 31 – August 4, 2016, Las Vegas, Nevada, United States

A127. Laughlin B, Bailey I, Rice S, Barati Z, Dowell K, and Drew K. “Targeted Temperature Management by Pharmacologically Inducing a Hibernation Like State”, 15th International Hibernation Symposium, July 31 – August 5, 2016, Las Vegas, Nevada.

A128. Drew KL, Tøien Ø, Kumar MM “Thermolytic efficacy of N6 cyclohexyladenosine in swine”, American Society for Neurochemistry, March 18 – 21, 2017, Little Rock, AR

A129. Rice S, D’Alessandro A., Drew K. “Metabolic Profiling and Physiological Monitoring in Hibernating Arctic Ground Squirrels during Acetate Infusions.” Experimental Biology, April 22 - 26, 2017, Chicago, IL

A130. Laughlin B, Bailey I, Rice S, Barati B, Drew K. “N6Cyclohexyladenosine, an A1 Adenosine receptor agonist as a Novel Thermolytic, Adjunctive Pharmacotherapy for Targeted Temperature Management”. Experimental Biology, April 22 - 26, 2017, Chicago, IL FASEB Journal, Volume 31, Issue 1 supplement April 1, 2017

A131. Frare C., Drew K.L., “Hypothalamic pathways involved in adenosine A1 receptor agonist-induced hibernation in the arctic ground squirrel (Urocitellus paryii)”, Experimental Biology, April 22 - 26, 2017, Chicago, IL

A132. Dowell K, Barati Z, Laughlin B, Drew KL. “Characterization of Cardiac Arrhythmias During N6-Cyclohexyladenosine Assisted Cooling of Rats”, Experimental Biology, April 22 - 26, 2017, Chicago, IL

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A133. Bailey IR, Laughlin B, Moore LA, Bogren LK, Barati Z, Drew KL. “Dynamic Surface Temperature Control Prevents Overcooling with N6-Cyclohexyladenosine in Rats”. Experimental Biology, April 22 - 26, 2017, Chicago, IL. FASEB Journal, volume 31, issue 1_supplement, April 1, 2017

A134. Drew KL, Tøien , Kumar MM, “6N-Cyclohexyladenosine Suppresses Shivering in Anesthetized Swine”. Experimental Biology, April 22 - 26, 2017, Chicago, IL FASAB Journal, Vol. 31, No. 1_supplement April 1, 2017 abstract lb607

A135. Bhowmick S, Barati Z, Shayegh F, Zucker E, Drew K. “Non-convulsive seizure as a potential variable in middle cerebral occlusion injury model”, Annual Meeting of the American Society for Neurochemistry, May 18 – 22, 2017, Little Rock, Arkansas, United States.

A136. Frare C., Lokken E., Drew K.L., Seasonal Changes in the Central Nervous System of the Arctic Ground Squirrel. Experimental Biology 2018, San Diego, CA, April 2018.

A137. Jenkins M.E., Frare C., Drew K.L., Neurochemical pathways involved in A1 adenosine receptor agonist-induced hibernation in the Arctic Ground Squirrel (Urocitellus parryii). Experimental Biology 2018, San Diego, CA, April 2018.

A138. Frare C., Jenkins M.E., Drew K.L., Adenosine A1 receptor agonist – induced hibernation: effects of agonist and seasons on neuronal pathways. American Society of Neurochemistry 2018, Riverside, CA, March 2018.

A139. Frare C., Drew K.L., Sleep-wake hypothalamic pathways characterizing the hibernating species Arctic Ground Squirrel (Urocitellus parryii). World Sleep 2017, Prague, Czech Republic, October 2017

A140. Jenkins M.E., Frare C., Drew K.L., Neurochemical pathways in the brainstem involved in A1 adenosine receptor agonist-induced hibernation in the Arctic Ground Squirrel (Urocitellus paryii). World Sleep 2017, Prague, Czech Republic, October 2017

A141. Laughlin B., Bailey I., Tagaban S., Drew K. Reversal of Peripheral and CNS Mediated A1 Adenosine Receptor Hypotension. American Society of Neurochemistry 2018, Riverside, CA, March 2018.

A142. Laughlin B.,Bailey I., Tagaban S., Drew KL Reversal of Peripheral and CNS Mediated A1 Adenosine Receptor Hypotension. Experimental Biology 2018, San Diego, CA, April 2018. FASEB Journal, Volume 32, Issue 1_supplement, April 1, 2018

A143. Rice SA, Barati Z, D’Alessandro A, Gehrke S, Reisz JA, Drew K Shifting nitrogen balance induces arousal from hibernation in arctic ground squirrels Experimental Biology 2018, San Diego, CA, April 2018.

A144. Mikes M, Rice SA, Bibus D, Drew K Analysis of experimental feed impacts on fatty acid profiles of captive and wild Arctic Ground Squirrels Experimental Biology 2018, San Diego, CA, April 2018.

A145. Rice, SA, Barati Z, D’Alessandro A, Drew, K Physiologic and metabolic consequences of shifting nitrogen balance in hibernating arctic ground squirrels 13 th International Conference on Brain Energy Metabolism (Valdivia, Chile March 7-10, 2018)

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Patents filed:Ma Y and Drew KL, Adapter between microdialysis guide cannula and microsensors. Provisional

Patent, United States Patent Office, filed Aug. 16, 2002 – Not pursued

Chen C-f and Drew KL, Digital microdialysis by operating droplets in a miniaturized probe. Provisional patent pending, United States Patent Office, July 20, 2006. Application number 60/831,924, denied.

Drew KL, Jinka TR, Bailey IR, Olson J, Carlson ZA, Bogren LK, Methods and compositions for the treatment of ischemic injury to tissue using therapeutic hypothermia. United States Patent Office, Application number 14/191,515 (Non-Provisional Utility Application), Filing Date: 2/27/14

Service:

Committee Appointments and Service:

University:

1995-1996 Appointed, Research Advisory Committee, IAB2001-2002 Appointed, Institutional Review Board 2001-2003 Appointed, Center for Nanosensor Technology, Seminar Coordinator2001-2003 Volunteer, Alaska Basic Neuroscience Program Summer Seminar Series

Coordinator2004-2006 Appointed, Research Advisory Committee, Institute of Arctic Biology2004-2006 Appointed, BICS-Central Animal Facility Project Committee2004-2014 Appointed, Institutional Animal Care and Use Committee2005 Appointed, Emergency Services Program Review Committee2005-present Appointed, Interdisciplinary Studies Program (INDS) Steering Committee2005-2006 Appointed, Leader EPSCoR Integrative Physiology Research Focus Area2006-present Appointed, Biomedical Health Sciences Planning Committee2007-2010 Appointed, Associate Director, Institute of Arctic Biology2007-2013 Appointed, Interdisciplinary neuroscience curriculum committee2007-2012 Appointed, Established biomedical scientist search committee2007 Volunteer, University Biomedical Research Conference org. comm..2010-2014 Appointed, Chair, Institutional Animal Care and Use Committee2009-2010 Appointed, Committee for design of research space in the new Life Sciences

Building2010-2011` Appointed, Biomedical Program Planning Group for the University of Alaska2013-present Faculty Advisor, Molecular Imaging Facility2014-2015 Appointed, Unit peer clinical-research-term-faculty committee 2014-2015 Appointed, Large Animal Program Review committee2014-2016 Appointed, INBRE Steering committee, UAF Science representative2014-2016 Appointed, INBRE MAC

Departmental:

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1999-2000 Appointed member, Search Committee (Assist. Professor, Organic Chemist)2000-2001 Appointed member, Search Committee (Laboratory Coordinator)2000-2001 Appointed member, Search Committee (Veterinary Technician)2001-2002 Appointed member, Search Committee (Director, Alaskan Basic

Neuroscience Program)2001-2002 Appointed member, Search Committees (Assistant Professor, Cell/Molecular

Neuroscientist)2001-2002 Appointed member, Search Committee (Assistant Professor, Analytical

Chemist)2003 Appointed Chair, Search Committee (Assistant Professor, Molecular

Physiologist)2009-2011 Appointed Associate Director of Biomedical Research, Institute of Arctic

Biology, UAF2011 Appointed Search Committee (Assistant Professor, Organic Chemistry)2011-present Appointed Coordinator for Biochemistry and Molecular Biology graduate

program (renamed to Biochemistry and Neuroscience in 2014)2011-2012 Appointed UA Biomedical Planning Group2014-2017 Appointed, Chair, Unit Peer Review Committee, Dept. Chemistry and

Biochemistry2015-present Coordinator, Biochemistry and Neuroscience Graduate Program2017 Appointed Chair, Search Committee (Assistant Professor, Biochemist)

Regional/National/International:

(i) Conferences: Organizer, Stroke therapies from hibernating squirrels, Winter Conference on Brain Research, Snowmass, CO, Jan., 1998.

International Organizing Committee, Monitoring Molecules in Neuroscience, Conway Institute of Biomolecular and Biomedical Research, June 16-19 2001, University College Dublin, Ireland.

Organizer, Alaskan Summer Neuroscience Conference, Fairbanks, Alaska, July 29, 2001, Fairbanks, Alaska

Organizer, Hypoxia tolerance; the less you want, the more you have, Winter Conference on Brain Research, Snowmass, CO, Jan., 2002

International Organizing Committee, Monitoring Molecules in Neuroscience, June 2003, Karolinska Institute, Stockholm, Sweden.

Organizer, Alaskan Summer Neuroscience Conference, Fairbanks, Alaska, July 14-15, 2002, Fairbanks, Alaska

Organizing Committee, Living in the Cold, July 2004, Vancouver, BC

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Organizer, Living without in Hibernation. Winter Conference on Brain Research. Copper Mountain, Colorado, Jan 29, 2004.

Organizer, University of Alaska Biomedical Research Conference. Fairbanks, Alaska, May 2012

Scientific Program Committee for the 13th International Conference on Brain Energy Metabolism (ICBEM), "Brain Energy Metabolism: How Energy Metabolism Shapes Brain Function; An Update” to be held March 7-10, 2018, in Valdivia, Chile

(ii) Societies/Agencies: American Heart Association, Alaska Affiliate, Research Committee, Anchorage, Alaska,

1995- 1998American Heart Association, External Reviewer, 1997American Heart Association, Northwest Affiliate, Research Committee, Seattle,

Washington, 1998 – presentAmerican Heart Association, Northwest Affiliate, Summer Science Fellowship Task Force,

1999 – presentAmerican Heart Association, National, Peer Review Steering Committee, 2000-2003Baker Fund Awards Committee, External Reviewer, 2002National Science Foundation, Ad-hoc reviewer, June, 2002National Institute of Deafness and Communication Disorders, Partnership Program

Committee, 1994 – 2005 NIH, Neurological Sciences and Disorders B Study Section, Ad Hoc Member, June, 2002Department of Defense (Army Research Office), External Reviewer, 2004, 2006Maryland Industrial Partnerships, University of Maryland, External Reviewer, 2004NIH, Biological Rhythms and Sleep [BRS] Study Section, Ad Hoc Member, June, 2005Alaska Drug Policy Reform, Board member, June 2003-presentNational Science Foundation, Ad-hoc reviewer, 2007-2017Maryland Industrial Partnerships, University of Maryland, External Reviewer, 2008MDCN-R (86) R15 AREA Applications Ad Hoc Reviewer, 2013NIH, ZRG1 BCMB-A (51) Study Section, Ad Hoc Member, March 2017

(iii) Grant:

Paid-Consultant, NIH Grant (1P50 NS34115), Ascorbate and glutathione in CNS injury, (Chesler, M., PI; Rice M.E., leader project 3), 1997-1998.

Consultant, NIH Grant, 1R01NS053898-01A2, Astrocytes and ischemic brain injury (Giffard, R.G. PI) 2007-2012

Paid-Consultant legal services regarding psychoactive drugs (2000-present)

(iv)Corporations: Consultant, Santa Fe Science & Technology, Inc., Santa Fe, New Mexico, 2000- 2003. Consultant, Space Works Enterprises, Inc., Atlanta, GA 2016-2017

(v) Ad Hoc Journal Reviewer:

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Journal of Neuroscience, Journal of Neurochemistry, Brain Research, Journal of Neuroscience Methods, Life Sciences, Psychopharmacology, Redox Report, Cellular and Molecular Biology, Journal of Experimental Biology, American Journal of Physiology, Hippocampus, Journal of Cerebral Blood Flow and Metabolism, Neurobiology of Aging, Journal of Physiology, Journal of Natural Products, Free Radical Biology and Medicine, Synapse, Journal of Comparative Neurology, Advances in Experimental Biology on Nitric Oxide, Comparative Biochemistry and Physiology, Bioessays, Analytical Chemistry, Neurobiology of Learning and Memory, Obesity, Brains and Behavior, Genes Brains and Behavior, PLoS One, Redox Biology, Temperature, Brain, Behavior and Immunity

(vi)Textbook Reviewer Horton et al., Principles of Biochemistry, 4th edition, Chapters 11-14. Prentice Hall, Upper

Saddle River, NJ

News Reports

1. https://www.nbcnews.com/mach/science/will-mars-colonists-snooze-their-way-red-planet- ncna824991

2. http://news.nationalgeographic.com/2017/10/animals-hibernation-science-nature-biology-sleep/ 3. http://nymag.com/scienceofus/2017/01/scientists-think-humans-may-one-day-be-able-to-

hibernate.html

4. http://www.airspacemag.com/space/hibernation-for-space-voyages-180962394/

5. http://www.wired.co.uk/article/animals-hibernating-treat-diabetes-alzheimers?sf53505317=1

6. https://www.theguardian.com/science/2015/apr/27/hibernation-astronaut-space-travel-mars

7. http://www.scienceforthepeople.ca/episodes/the-big-sleep

8. http://www.smithsonianmag.com/science-nature/can-humans-ever-harness-power-hibernation- 180961835/#7DwVc77mCfWvp3eZ.99

9. http://qz.com/616304/researchers-are-freezing-patients-to-suspend-death-and-bring-them-back-to- life/

10. http://www.livescience.com/54982-why-do-animals-hibernate.html

11. https://www.outerplaces.com/science/item/12004-scientists-say-cryosleep-is-the-only-way-for- humans-to-achieve-interstellar-travel

12. http://motherboard.vice.com/read/a-brief-history-of-cryosleep

13. http://www.newsminer.com/science_and_technology/uaf-researchers-adapt-stanford-method-to- make-transparent-brains/article_3ad152d2-fdfe-11e4-a8c2-17e079ebd0b1.html

14. Therapeutic Hibernation, KTVF Channel 11 Fairbanks https://www.youtube.com/watch?v=X0fIxBU6bW8

15. Washington Post, April 14 by Eric Niilerhttp://www.washingtonpost.com/national/health-science/hibernation-for-humans-may-not-be-a-pipe-dream-forever/2015/04/13/9f60d47c-c440-11e4-9ec2-b418f57a4a99_story.html

16. C&E News – Therapeutic Hypothermia, April 5, 201517. Animals, April 30, 2015, http://modernnotion.com/can-we-make-humans-hibernate/18. http://www.rokepie.com/interstellar/19. Smithsonian.com http://www.smithsonianmag.com/smart-news/scientists-are-trying-figure-out-if-

humans-can-hibernate-180955018/?no-ist

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http://www.newsminer.com/science_and_technology/uaf-researchers-adapt-stanford-method-to-make-transparent-brains/article_3ad152d2-fdfe-11e4-a8c2-17e079ebd0b1.html

http://www.newsminer.com/science_and_technology/uaf-researchers-adapt-stanford-method-to-make-transparent-brains/article_3ad152d2-fdfe-11e4-a8c2-17e079ebd0b1.html

http://motherboard.vice.com/read/a-brief-history-of-cryosleep

https://www.outerplaces.com/science/item/12004-scientists-say-cryosleep-is-the-only-way-for-humans-to-achieve-interstellar-travel

https://www.outerplaces.com/science/item/12004-scientists-say-cryosleep-is-the-only-way-for-humans-to-achieve-interstellar-travel

http://www.livescience.com/54982-why-do-animals-hibernate.html

http://qz.com/616304/researchers-are-freezing-patients-to-suspend-death-and-bring-them-back-to-life/

http://qz.com/616304/researchers-are-freezing-patients-to-suspend-death-and-bring-them-back-to-life/

http://www.smithsonianmag.com/science-nature/can-humans-ever-harness-power-hibernation-180961835/#7DwVc77mCfWvp3eZ.99

http://www.smithsonianmag.com/science-nature/can-humans-ever-harness-power-hibernation-180961835/#7DwVc77mCfWvp3eZ.99

http://www.scienceforthepeople.ca/episodes/the-big-sleep

https://www.theguardian.com/science/2015/apr/27/hibernation-astronaut-space-travel-mars

http://www.wired.co.uk/article/animals-hibernating-treat-diabetes-alzheimers?sf53505317=1

http://www.airspacemag.com/space/hibernation-for-space-voyages-180962394/

http://nymag.com/scienceofus/2017/01/scientists-think-humans-may-one-day-be-able-to-hibernate.html

http://nymag.com/scienceofus/2017/01/scientists-think-humans-may-one-day-be-able-to-hibernate.html

http://news.nationalgeographic.com/2017/10/animals-hibernation-science-nature-biology-sleep/

https://www.nbcnews.com/mach/science/will-mars-colonists-snooze-their-way-red-planet-ncna824991

https://www.nbcnews.com/mach/science/will-mars-colonists-snooze-their-way-red-planet-ncna824991


20. http://rt.com/news/250977-human-hibernation-space-travel/21. http://www.scarysquirrel.org/science/siksik/22. http://www.techtimes.com/articles/47378/20150421/esa-mulls-going-interstellar-style-is-human-

hibernation-possible.htm23. https://www.linkedin.com/pulse/space-crew-hibernation-sonja-van-der-veen24. http://projectavalon.net/forum4/showthread.php?81644-Is-human-hibernation-possible25. http://www.express.co.uk/news/nature/571629/Could-humans-hibernate-Scientists-claim-

astronauts-will-be-put-into-sleep-like-state26. http://www.lifeextensionretail.com/NewsArticleDetails.aspx?

NewsID=23714&Section=AGINGhttp://systemunknown.com/can-humans-hibernate-in-space-9303692/

27. http://www.washingtonpost.com/national/health-science/hibernation-for-humans-may-not-be-a-pipe-dream-forever/2015/04/13/9f60d47c-c440-11e4-9ec2-b418f57a4a99_story.html

28. http://www.theguardian.com/science/2015/apr/10/arctic-ground-squirrel-key-alzheimers-cure29. http://www.popsci.com/science/article/2011-09/scientists-successfully-induce-hibernation-arctic-

ground-squirrels30. http://www.popsci.com/science/article/2011-09/scientists-successfully-induce-hibernation-arctic-

ground-squirrels31. http://www.capitalcityweekly.com/stories/081011/out_869521157.shtml32. http://www.newscientist.com/blogs/shortsharpscience/2011/08/andy-coghlan-reporter-by-

study.html33. http://www.adn.com/life/health/story/8384687p-8279997c.html34. http://www.hhmi.org/bulletin/sept2002/wild/wild2.html35. http://jeb.biologists.org/cgi/content/full/207/18/i36. http://www.alaska.edu/eHealth/VitalSigns/video_productions/episode_2.html37. http://app1.unmc.edu/publicaffairs/todaysite/sitefiles/today_full.cfm?match=116438. http://www.the-scientist.com/article/display/14183/39. http://www.sciamdigital.com/index.cfm?

fa=Products.ViewIssuePreview&ARTICLEID_CHAR=B3AA39F1-2B35-221B-63CD1B9A1E12435140. http://www.sciencenews.org/pages/sn_arc97/12_6_97/bob1.htm41. http://www.usnews.com/usnews/health/articles/050523/23hibernate.htm42. Travis J, Chilled Brains, Science News. 1997 Dec 6.

http://www.sciencenews.org/pages/sn_arc97/12_6_97/bob1.htm43. Roth MB, Nystul T. Buying time in suspended animation. Sci Am. 2005 Jun;292(6):48-55. 44. Hobson K. A winter's sleep. Hibernation's secrets may help treat a host of human afflictions. US

News World Rep. 2005 May 23;138(19):60-1.45. Hannah Guillaume, Scripps Howard Foundation Wire Hannah Guillaume, Scripps Howard

Foundation Wire, picked as full page article by Anchorage Daily News, published Nov. 7, 2006. Secrets of the squirrel Medical implications of rodents' hibernation give Fairbanks researchers something to chew on http://www.adn.com/life/health/story/8384687p-8279997c.html

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Community Service:1990-present Expert Witness, DUI and all aspects of neuropharmacology of drugs affecting

the brain and behavior (marijuana, ritalin, alcohol, cocaine, amphetamine, benzodiazepines etc.)

1997-present Science Potpouri, College of Science, Engineering and Mathematics, UAF 1999-present Science Education, Wood River Elementary School, “Dr. Science”2003 Chilled Brains, Lathrop High School2004 Pharmacology of drugs of abuse, Fairbanks North Star School District -in-

service 2004 Pharmacology of drugs of abuse, North Pole Alternative High School 2004 Channel 11 interview concerning questions on Ballot Measure 22005 Invited testimony for public hearing on Alaska SB 74 and HB 96 2005 Chilled Brains, UAF Museum Lecture Series2005 CNSM Science Potpourri2010-2011 Science for Alaska lecture series (Fairbanks, Anchorage, Juneau)2006-present Expert Witness for civil and criminal cases related to behavioral effects of

psychotropic drugs and pharmacokinetics2011-2013 Hibernation lecture – Murie Learning Center, Denali Park Alaska2014 KOTZ radio interview, Hibernation lecture, Cold Foot Museum2015 Osher Life-Long Learning Institute. Lecture, What Now? Marijuana

Legalization in Alaska2015 Mayor’s working group on Proposition 2

Society Memberships:

1985-present Society for Neuroscience2001-2002 President, local chapter Society for Neuroscience1998-present American Society for Neurochemsitry2000-present International Society for Neurochemistry2000-present International Society of Cerebral Blood Flow and Metabolism

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curriculum vitae - uaf.edu€¦ · web viewliving in a seasonal world: ... drew kl. 1h-nmr...

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