Kozar RA

CURRICULUM VITAE

Rosemary A. Kozar, MD, PhDShock Trauma Center

University of Maryland, Baltimore, MD

Contact Information

Business Address: Shock Trauma Center22 South Green St,Room S4D07Baltimore, MD 21015

Business phone: (410)328-7611Email Rkozar@umm.edu

Education:

1980 B.S., Rehabilitation, Indiana University of PA1982 Post-baccalaureate, University of Pittsburgh1986 M.D., Temple University School of Medicine1992 Ph.D., Molecular Physiology and Biophysics, Baylor College of Medicine, Henry Pownall, thesis advisor

Post Graduate Education and Training

1986-1987 Internship, General Surgery, University of TX Health Science Center at Houston

1987-1988 General Surgery, University of TX Health Science Center at Houston1992-1995 General Surgery, Temple University School of Medicine1999-2000 Fellowship, Surgical Critical Care, University of TX Health Science Center at Houston

Certifications:

1987 Diplomate, American Board of Medical Examiners1996 Diplomate, American Board of Surgery, Recertification 20152000 Certificate of Added Qualifications in Surgical Critical Care, Recertification 2011

Medical Licensures:

Inactive Pennsylvania Active TexasActive Maryland

Kozar RA

Employment History:

Academic Appointments:

1995-1996 Clinical Instructor, Surgery, MCP Hahnemann University 1996-1999 Assistant Professor of Surgery, MCP Hahnemann

University 1999 Interim Director of Trauma and Critical Care, Hahnemann University Hospital1999- 2003 Assistant Professor of Surgery, University of TX Health

Science Center Houston2001-present Faculty Member of the Graduate School of Biomedical Sciences, University of TX Health Science Center Houston2003 –2008 Associate Professor, Surgery, University of TX Health

Science Center Houston2008- present Professor with tenure, Surgery, University of TX Health

Science Center Houston2008- present James “Red” Duke Distinguished Professor in Surgery, 2010-2011 Medical Director, Shock Trauma ICU, Memorial Hermann Hospital; Houston, TX2006-2012 Director of Trauma, Memorial Hermann Hospital, Houston, TX2012-2014 Vice Chair of Research and Academic Development, Surgery, University of TX

Health Science Center Houston2014-present Director of Translational Research, Shock Trauma Center, University of

Maryland, Baltimore, MD2014-present Professor of Surgery with tenure, Department of Surgery, University of

Maryland, Baltimore, MD2015-present Associate Director of the Center for Shock Trauma Anesthesia Research

(STAR), University of Maryland, Baltimore, MD 2016-present Acting Director of the Charles “McC” Mathias National Study Center for Trauma

and EMS Hospital Appointments:

1995-1999 Hahnemann University Hospital; Broad and Vine; Philadelphia, PA 191021995-1999 Medical College of Pennsylvania; 3300 Henry Avenue; Philadelphia, PA 191292013-present Lyndon B. Johnson General Hospital; Houston, TX 770301999-present Memorial Hermann Hospital; 6411 Fannin; Houston, TX 770302014-present Shock Trauma Center, University of Maryland, Baltimore, MD 21015

Professional Society Memberships:

1990 Initiate, American College of Surgeons1991 Member, Association of Academic Surgeons1995 Member, Association of Women Surgeons1998 Fellow, American College of Surgeons1998 Member, Society of Critical Care Medicine

Kozar RA

1999 Member, American Society of Parenteral and Enteral Nutrition2000 Member, Shock Society2002 Member, Society of University Surgeons2004 Member, Western Trauma Association2004 Member, American Association for the Surgery of Trauma2006 Member, American Physiology Society2011 Member, American Surgical Association

Honors and Awards:

1985 Boehringer Ingelheim National Pharmacology Award 1986 The Doctor Herman Brown Award for Excellence in the Study of the Art and Science of Surgery, Temple University School of Medicine1990 Career Development Award (NRSA). NIH. 1994 Delaware Valley Vascular Society Residents Competition, First prize1998 Mary Dewitt Petit Research Fellowship. Medical College of Pennsylvania 2002 Frank Webber Prize for Student Research, Third Place,University of Texas- Houston, Research Mentor for Craig Messick, medical student.2002 Dean’s Teaching Excellence Award, University of Texas-Houston2002 Career Development Award (K08). NIH. 2003 Dean’s Teaching Excellence Award, University of Texas-Houston2004 Research Mentor for Alpha Omega Alpha Student Research Fellowship recipient, Keith Gates, Medical student at the University of Texas-Houston2004 Dean’s Teaching Excellence Award, University of Texas- Houston2005 Research Mentor for the winner of the Dr. Edward S. Reynolds Memorial Award in Pathology, Adam Childs, Medical student, at the 46th Annual National Student Research Forum in Galveston, TX2005 Dean’s Teaching Excellence Award, University of Texas- Houston2005-2006 Master Teachers Research Award, University of Texas-Houston2006-2007 Master Teacher Research Award, University of Texas-Houston2008 T.R.U.E. Research Foundation Endowment Award2010 C. Frank Webber Prize for Student Research, First Place, University of Texas- Houston, Research Mentor for Ryan Brown, medical student 2013 Top Doctors 2013 Houstonia, Houston, TX2014 American Medical Association Seed Grant, Research mentor for Anthony LeBlanc2015 Nina Starr Braunwald Award by the Association of Women Surgeons

Clinical Activities:

Clinical Expertise:

Board certified in general surgeryAdded qualifications in surgical critical careClinical and research focus are in trauma and critical care

Kozar RA

Administrative Service:

University of Maryland: Director of Translational Research, Shock Trauma CenterAssociate Director of Shock Trauma Anesthesia ResearchActing Director of the Charles “McC” Mathias National Study Center for Trauma and EMS

CommitteesDirector Shock Trauma Fellows Research ConferenceFinance Committee Shock TraumaTeaching/EducationLocalATLS 8/18/2016ATOM 11/10/2015 Abdominal Examination Workshop 11/11/15                              Introduction to Clinical Medicine II                              University of Maryland School of Medicine                              1 hours, 20 second-year medical studentsSurgical Bootcamp, Sepsis February 2015

University of Marlyland School of Medicine 1.5 hours, 12 forth-year medical students

Surgical Bootcamp, Sepsis February 2016 University of Marlyland School of Medicine

1 hour, 14 forth-year medical studentsFellows conference, approximately every second month 2 hours

National TeachingAAST Curriculum in Acute Care Surgery- mangled extremity October 2015ACS TQUP Best Practices in the Management of Orthopedic Trauma November 2015AAST Curriculum in Acute Care Surgery- vascular access for REBOA February 2016

National Service:

Editorial Boards2006 -2012 Journal of Surgical Research2003—present American Journal of Surgery2008-2010 Section editor, Up to Date2007-present JPEN2011-present SHOCK2011-present Journal of Trauma of Acute Care Surgery2016-present Trauma Surgery and Acute Care Open

EditorAssociate Editor for In Comprehensive Critical Care: Adult. Roberts PR, Todd SR (Eds). Society of Critical Care Medicine, 2nd edition 2016, in press.

Kozar RA

Study Sections

2007NIH: Special Emphasis Panel, NIGMS. August 2007, reviewer2008-2010American Heart Association Peer Review Committee 2011 April NIH: Special Emphasis Panel, NIGMS April 20112011 October NIH: Ad hoc reviewer, NIA 2013 April NIH: reviewer for loan repayments NIGMS, April 20132013 November NIH: reviewer for NRSA grants, November 20132014 April NIH: reviewer for loan repayments NIGMS, April 20142014 June-July NIH: reviewer for T32 grants NIGMS 2015 NIH/NIGMS RO1 Multi-Center Clinical Trial Special Emphasis Panel, October 20152105 NIH/NIGMS Special Emphasis Panel, November 2015 2106 NIH/NIGMS Special Emphasis Panel, May 20162016 NIH/NIGMS Special Emphasis Panel, August 20162014-present NIH Surgery, Anesthesia, Trauma Study section

National Committee Membership and Leadership Positions

2002 Councilor for the Association of Women Surgeons2002 Education Committee, Association of Academic Surgeons2003 Education Committee, Society of University Surgeons2002 Chair of Education Committee, Association of Academic Surgeons2004 Chair of Membership Committee, Association of Women

Surgeons 2005 American College of Surgeons-South TX Chapter Representative for the Association

of Women Surgeons2005-2007 Chair, Education Committee and Executive Council, Society of University

Surgeons 2005-2014 Member of the American College of Surgeons Resident Curriculum Steering

Committee and chapter author2005 Co-chair, Symposium on Health and Career

Disparities. Shock Society2005-2007 Secretary, Association of Women Surgeons2006-2007 American Association for the Surgery of Trauma-ACS-NIH Scholarship Committee2006-2009 Expert Panel Member for the Texas State Medical Board2007-2013 American College of Surgeons Planning Committee and Core faculty for General Surgery Review Courses 2007 Research Host for Physiology Research Fellowship; American Physiology Society2007-2010 Shock Society Rules Committee2007-2008 Vice President, Association of Women Surgeons2007-2010 American Association for the Surgery of Trauma Multi-institutional Trials Committee2008-present American College of Surgeons Regional Committee on Trauma

Kozar RA

2009- present American College of Surgeons National Committee on Trauma20009-present American College of Surgeons Women in Surgery Portal Editor2008-2010 Western Trauma Association Publications Committee2008-2012 Western Trauma Association Board of Directors2008-present Consultant for in-training exam, American Board of Surgery2008-2009 Association of Women Surgeons, President Elect2009-2010 Association of Women Surgeons, President 2009-2013 American Association for the Surgery of Trauma; Branding Committee2009-2010 Advisory Board for Covidien’s Women in Surgery Platform2009-present American College of Surgeons, Women in Surgery Committee2009-2013 Executive Council, Shock Society2011-present Chair, Multicenter Trials, Western Trauma Association2011-2013 American Association for the Surgery of Trauma, Bylaws Committee2011-present Association of Academic Surgeons Foundation Board2011-present American College of Surgeons Committee on Trauma, Best Practice Committee2012-present American Association for the Surgery of Trauma Acute Care Surgery

Committee2012-present Shock Society Development Committee2013-present American Association for the Surgery of Trauma Geriatrics Committee2013-2016 American Association for the Surgery of Trauma Membership Committee2013-2016 American Association for the Surgery of Trauma Scholarship Committee2013-present National Trauma Institute Board of Directors2013-present American College of Surgeons, Chair, Women in Surgery Committee2013-2016 American Association for the Surgery of Trauma Board of Managers2014 Associate Examiner, American Board of Surgery2014-present Chair, Verification Committee for the ACS Committee on Trauma2014-present Executive Committee, American College of Surgeons Committee on Trauma2014-present Science Committee, National Trauma Institute2014-2105 President-elect, Shock Society2015- 2016 President, Shock Society

Mentoring:

Medical students, research Anthony LeBlance, medical student 2013-presentJeff Gerber, medical student 2010-2011 Christine Haugen medical student 2011-2014 Medical students, summer researchAndrew Kline; Medical student; summer 1998Craig Messick; Medical student; summer 2002Holland Patterson; Medical student; summer 2002Keith Gates; Medical student; summer 2002-2003 AOA grant scholarMarshall Smith; Medical student; summer 2003 Justin Weatherall; Medical student; summer 2003Elizabeth Verner-Cole; Medical student; summer 2003

Kozar RA

Michael Adam Childs; Medical student; summer 2004Colt Melton; Medical student, summer 2005Julie Sprunt, Medical student summer 2007Stephanie Martin, Medical Student summer 2008Ryan Brown, Medical Student summer 2010Aritra Sen, Medical Student summer 2011Adam Gover, Medical student summer 2012Richard Witkov, medical student summer 2013Rick Wawrose, medical student 2013-2014Anthony LeBlance, medical student 2014-2015 Undergraduate students, researchLynelle Thorpe; summer 2001Meschak Mwangi, NIH-funded minority student supplement recipient, summer 2005 Jonhthan Berrout; summer 2006Rick Wawrose: student summer 2012 Residents, research James Cipolla; Surgical Resident; 1998-1999Rachael Santora, Surgical Resident 2008-2009 Post-doctoral fellowsNorio Sato 2004-2006Kechen Ban 2006-2010Zhanglong Peng 2009-2011Ricky Hawood-Watson 2012-2013

FacultyBrittney Williams 2017- present

National mentorship:Women in Surgery Committee of the American College of Surgeons Carrie Sims 2013-2014 Stephanie Bonne 214-2015 Jacinthe Lampron 2015-2016 Susannah Nicholson 2016-2017

Young Fellows mentorship program of the American College of SurgeonsTyler Becker 2015-2106

METS (Mentoring for Excellence in Trauma Surgery) of the American College of Surgeons Katie Wiggins 2015-present

PhD thesis committee Cecilie Jepsen, University of Copenhagen, Denmark 2017-present

Kozar RA

Grant Support

Active Grants:

9/13/2013 – 5/31/2017 Rosemary Kozar, PI, 25% effortSyndecan shedding after trauma and hemorrhagic shockNIH RO1 Annual direct costs averages $297,000Total direct costs $800,000

3/15/2016- 8/15-2017 Rosemary Kozar, PI, 3% effortEffect of hypobaria after polytrauma on gut function and its microbiotaAir ForceTotal costs $257,000

Completed Grants:07/1/2013-06/30/2018 Rosemary Kozar, Co-Inv 2%; PI-John HolcombNIH T32 Training grantTranslational Research in Trauma and Hemorrhagic ShockTotal direct costs $1,835,640Associate Director 3/1/2014 to 10/31//2014 Rosemary Kozar, Faculty sponsor 0% effortAmerican Medical Association, peer-reviewedLuminal Tranexamic Acid Abrogates Acute Lung Injury After Hemorrhagic Shock via Syndecan-1Total direct costs $2,443

1/1/2013- 10/31/20114 Rosemary Kozar, Site PI 2% effortNIH R03 multi-center trialA Randomized Trial of Supplemental Parenteral Nutrition in Under and Over Weight Critically Ill Patients: The TOP UP TrialPer diem cost per patient enrolledResponsible for overall study coordination of an ICU-based nutrition study

05/01/2014–4/30/2019 Rosemary Kozar, Co-inv; PI-Kone T35 Training grantShort Term Research TrainingTotal direct costs: $561,606Member of the steering committee

1-2010 to 6-30-2014 Rosemary Kozar, Co-Inv, 25% effort; PI-Bryan CottonDOD Evaluation of lyophilized plasma in models of vascular injury and hemorrhagic shock.Annual direct costs

Kozar RA

Total direct costs $1,500,000

9-2007 to 6-2012 Rosemary Kozar, PI 30% effortNIH RO1 Induction of molecular mediators by enteral nutrients in the postishemic gut.Total direct costs $1,400,000

8-2011 to 7/2013 Rosemary Kozar, Co-Inv 0% effortNational Trauma Institute Multi-center study; peer reviewedSplenic Injury Prospective Outcomes TrialTotal direct costs $21,100Responsible for overall study coordination of a trauma related clinical study

2/2009 to 9/2013 Rosemary Kozar, Pi ?DOD This award was a sub-award under a larger clinical trial Inflammation and Adiposity After Hemorrhagic Shock and Resuscitation. Total direct costs $150,000

3-2011 to 2-2012 Rosemary Kozar, faculty mentor 0% effortAlbert and Ethel Herzstein Charitable Foundation. Peer-reviewedNovel assessment of admission sarcopenia and nutritional adequacy in the injured elderly requiring ICU admission. Total direct costs $11,000.

6-2004 to 5-2009 Rosemary Kozar, Project PI 10% effort; Program PI Fred MooreNIH P50 Impaired Gut Transit and Hypertonic SalineTotal direct costs $1,372,602.

7-2006 to 6/2010 Rosemary Kozar, Mentor 0% effortNIH T-32 Training Grant Role of the gut in postinjury multiple organ failure Mentor. Total direct $1,278,732.

5-2007 to 4-2009 Rosemary Kozar, PIT.R.U.E. Research Foundation. Role of Endothelial and Epithelial Glycocalyx in protection by plasma during hemorrhagic shock. Total direct $109,000..

8-2002 to 7-2007 Rosemary Kozar, PI 75% effortNIH KO8Gut Ischemia/Reperfusion Injury is Modulated by Enteral Nutrients. Total direct costs $596,430

2005-2007 Rosemary Kozar, PI 0% effort

Kozar RA

Master Teacher Education Grant; University of Texas-HoustonAn Intense Tutorial Program for At-Risk Students to Enhance Success on the NBME Surgery Shelf Exam. Total direct costs $30,000.

1990-1992 Rosemary Kozar, PINIH NRSA Free radical-induced alterations in endothelial cell function. Total Direct costs $46,000. 7-1998 to 6-1999 Rosemary Kozar, PI Mary DeWitt Petit Research Fellowship. Antioxidant defense during recovery from acute lung injury. Total direct costs $10,000.7-1998 to 6-1999 Rosemary Kozar, PI

Publications

Peer Reviewed Publications

1. Kozar RA, Pitale M, White JV, McGowen J, Cundy K, Comerota A. Mechanism of direct antibiotic protection of Dacron vascular grafts. Current Surgery 1987; 44(3):214-216.

2. White JV, Freda J, Kozar RA, Serfass D, Cundy K, Comerota AJ, Ritchie WP. Does bacteremia pose a direct threat to synthetic vascular grafts? Surgery 1987;

102(2):402- 408.3. Kozar RA, McKeone BJ, Pownall HJ. Free radical-induced alterations in endothelial

cell function. J Surg Res. 1994;56:32-36.4. Kozar RA, McKeone BJ, Pownall HJ. Mechanism of cellular phospholipid efflux. J

Surg Res. 1993; 55:548-52. 5. Karam JA, Kozar RA. Solitary rupture of an accessory spleen. J Trauma. 1998 Jan;

44(1):220-221. 6. Klein AJP, Kozar RA, Kaplan LJ. Traumatic hematuria and polycystic kidney disease.

The American Surgeon. 1999; 65 (5):464-466.7. Kozar RA, Weibel CJ, Abedin MZ, Cipolla J, Klein D, Haber M, Trooskin SZ.

Antioxidant enzyme induction during recovery from acute lung injury. Crit Care Med. 2000; 28 (7):2486-2491.

8. Hassoun HT, Kone BC, Kozar RA, Lai M, Moore FA. -Melanocyte stimulating hormone augments gut ischemia-reperfusion induced heme oxygenase expression. Surgical Forum. 2001; LII:12-14.

9. Garner GB, Ware DW, Cocanour CS, Duke JH, McKinley BA, Kozar RA, Moore FA. Vacuum assisted wound closure provides early fascial reapproximation in trauma patients with open abdomens. Am J Surg 2001;182(6):630-638.

10. Moore FA, Cocanour CS, McKinley B, Kozar RA, DeSoignie R, VonMaszewski M, Weisbrodt N. MMC’s exist after trauma and predict enteral tolerance. J Trauma 2001;51(6):1075-1082.

11. Kozar RA, Kaplan LJ, Cipolla J, Meija J, Haber M. Laparoscopic repair of traumatic

Kozar RA

diaphragmatic injuries. J Surg Res. 2001;97(2):164-171.12. Hassoun HT, Weisbrodt NW, Kozar RA, Mercer DW, Moody FG, Moore FA. Inducible

nitric oxide synthase mediates gut ischemia/reperfusion-induced ileus only after severe insults. J Surg Res.2001 May 15;97(2):150-154.

13. Fuchs BD, Smull G, Chang B, McMaster J, Getsy J, Kozar RA. Under-appreciation of sleep disorders as a cause of motor vehicle crashes. American Journal of Emergency Medicine. 2001;19 (7):575-578.

14. Nunes LW, Simmons S, Hallowell MJ, Kinback R, Trooskin S, Kozar RA. Diagnostic performance of trauma ultrasound in identifying abdominal/pelvic free fluid and diagnostic performance of ultrasonographic free fluid in identifying significant abdominal/pelvic injury. Academic Radiology. 2001; 8(2):128-136.

15. Nunes LW, Simmins S, Kozar RA, Kinback R, Hallowell MJ, Mulhern C. Feasibility and profitability of a radiology department’s providing a trauma ultrasound examination for abdominal/pelvic free fluid as part of a trauma alert team. Acad Rad. 2001; (1):88-95.

16. Hassoun HT, Kozar RA, Kone BC, Safi HJ, Moore FA. Intraischemic hypothermia differentially modulates oxidative stress proteins during mesenteric ischemia/reperfusion. Surgery 2002 Aug; 132(2): 369-76.

17. McKinley BA, Cocanour CS, Kozar RA, Ware DN, Sailors RM, Marquez A, Moore FA. Normal vs supranormal O2 delivery goals in shock resuscitation: the response is the same. J Trauma. 2002 (53) 825-32.

18. Balogh Z, McKinley BA, Cocanour CS, Kozar RA, Ware DN, Holcomb JB, Moore FA. Secondary compartment syndrome: an elusive complication of shock resuscitation. Am J Surg. 2002; 184 (6) 538-43; discussion 543-4.

19. Kozar RA, Schultz SG, Hassoun HT, DeSoignie R, Weisbrodt NW, Haber MH, Moore FA. The type of sodium-coupled solute modulates small bowel mucosal injury, transport function and ATP after Ischemia/reperfusion injury in rats. Gastroenterology 2002 Sep;123(3):810-6.

20. Kozar RA, Sen H, Hassoun HT, DeSoignie R, Moore FA. Specific enteral nutrients alter mucosal blood flow during gut ischemia/reperfusion. JPEN 2002 Jul-Aug; 26(4): 226-229.

21. Kozar RA, McQuiggan MM, Moore EE, Kudsk K, Jurkovich G, Moore FA. Postinjury enteral tolerance is reliably achieved by a standardized protocol. J Surg Res. 2002; 104(1):70-75.

22. McKinley BA, Kozar RA, Cocanour CS, Marquez A, Sailors RM, Ware DN, Moore FA. Trauma resuscitation: female hearts respond better. Arch of Surgery 2002; 137(5):578-584.

23. Hassoun HT, Zou L, Moore FA, Kozar RA, Weisbrodt NW, Kone C. -melanocyte stimulating hormone protects against mesenteric ischemia/reperfusion injury. Am J Physiol Gastrointest Liver Physiol.2002 Jun; 282(6):G1059-1068.

24. Suliburk JW, Ware DN, Balogh Z, McKinley BA, Cocanour CS, Kozar RA, Moore FA. Vacuum-assisted wound closure achieves early fascial closure of open abdomens after severe trauma. J Trauma. 2003;55 (6):1155-1160; discussion 1160-1161.

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25. Sato N, Kozar RA, Zou L, Moore-Olufemi S, Weisbrodt N, Moore FA. Cyclooxygenase-2 (COX-2) plays a role in mediating impaired intestinal transit after gut ischemia/reperfusion (I/R). J Surg Res. 2003; 114(2),287-288.

26. Balogh Z, McKinley B, Cox C, Allen S, Cocanour S, Kozar RA, Weisbrodt N, Moore FA. Abdominal compartment syndrome: A modifiable link between traumatic shock and multiple organ failure. Shock. 2003;20 (6) :483-492.

27. Balogh Z, McKinley B, Cocanour C, Kozar RA, Cox C, Moore FA. Patients with impending abnormal compartment syndrome do not respond to early volume loading. Amer J Surg. 2003;186:602-608.

28. Balogh Z, McKinley B, Cocanour C, Kozar RA, Valdivia A, Sailors RM, Moore FA.Supra-normal trauma resuscitation causes more cases of abdominal compartment syndrome. Archives Surg. 2003;138 (6) 637-642.

29. Kozar RA, Lucci A, Azzizadeh A, Miller CC, Cocanour CS, Potts J, Fischer C, Brundage SI. A brief intervention by surgeons can influence medical students towards a career in surgery. J Surg Res. 2003; 3 (1) 166-169.

30. Attuwaybi BO, Hassoun H, Kozar RA, Moore FA. Hypothermia protects against gut ischemia-reperfusion (I/R) induced impaired intestinal transit by inducing heme oxygenase-1 (HO-1). J Surg Res. 2003 Nov;115(1):48-55.

31. Mangram A, Kozar RA, Gregoric I, Grant, P, Cocanour CS, Moore FA:Unsuspected blunt cardiac injuries that required operative intervention. J. Trauma. 2003; 54 (2) 286 288.

32. Holcomb JB, McMullin NR, Kozar RA, Lygas MH, Moore FA: Morbidity fromrib fractures increases after age 45. J Am Coll Surg 2003; (196) 549-555.

33. Balogh Z, McKinley BA, Holcomb JB, Miller CC, Cocanour CS, Kozar RA, Moore FA. Bth primary and secondary abdominal compartment syndrome can be predicted early and are harbingers of bad outcome. J Trauma. 2003; 54 (5): 848-59.

34. Marr AB, McQuiggan MM, Kozar RA, Moore FA. Gastric feeding as an extension of an established enteral nutrition protocol. Nutrition in Clinical Practice. 2004; 19(5):504-510.

35. Kozar RA, Schultz SG, Verner-Cole E, Bick R, DeSoignie R, Poindexter B, Moore FA. Enteral arginine, an immune enhancing agent, impair gut barrier function following mesenteric ischemia/reperfusion. J Trauma. 2004; 56:1150-1156.

36. Marr AB, Moore FA, Sailors M, Valdivia A, Selby J, Kozar RA, Cocanour C, McKinley BA. Preload Optimization using. “Starling Curve” Generation during shock resuscitation: Can it be done? Shock 2004; 21(4): 300-305.

37. Attuwaybi BO, Kozar RA, Moore-Olufemi SD, Sato N, Hassoun HT, Weisbrodt NW,Moore FA. Heme Oxygenase-1 Induction by hemin protects against gut ischemia/reperfusion injury. J Surg Res. 2004 May 1;118(1):53-57.

38. Kozar RA, Schultz SG, Bick RJ, Poindexter BJ, DeSoignie R, Moore FA. Enteral glutamine but not alanine maintains small bowel barrier function after ischemia/reperfusion injury in rats. Shock 2004 May; 21(5): 433-437.

39. Kozar RA, Anderson K, Chaves-Escobar S, Theil M, Brundage S. Preclinical students: Who are surgeons? J Surg Res. 2004; 119:113-116.

40. Attuwaybi B, Kozar RA, Gates KS, Moore-Olufemia S, Sato N, Weisbrodt NW, Moore FA. Hypertonic saline prevents inflammation, injury, and impaired intestinal transit

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after gut ischemia/ reperfusion by inducing heme oxygenase 1 (HO-1) enzyme. J Trauma. 2004 Apr; 56(4):749-758.

41. Kozar RA, Holcomb JB, Macatis J, DeSoignie R, Moore FA. Superior mesenteric artery occlusion (SMAO) models shock-induced gut ischemia/reperfusion. J Surg Res. 2004; 116(1):145-150.

42. Kozar RA, Moore FA, Cothren C, Moore EE, Sena M, Bulger E, Miller C, Eastridge B, Acheson E, Brundage S, Tataria M, McCarthy M, Holcomb J. Risk factors for hepatic morbidity following nonoperative management: Multicenter study. Archives of Surgery 2006 May;141(5):451-459.

43. Gonzalez EA, Kozar RA, Suliburk JW, Weisbrodt NW, Mercer DW, Moore FA. Hypertonic saline resuscitation after mesenteric ischemia/reperfusion induces ileal apoptosis. J Trauma 2005 Nov;59(5): 1092-1098.

44. Kozar RA, Moore JB, Niles SE, Moore EE, Cothren CC, Hartwell E, Moore FA. Complications of nonoperative management of high-grade blunt hepatic injuries. J Trauma 2005 Nov;59:1066-1077.

45. Sato N, Kozar RA, Weatherall J, Zou L, Attuwaybi B, Moore-Olufemi SD, Weisbrodt NW, Moore FA. PPAR gamma mediates COX-2 induced gut dysfunction in a rodent model of mesenteric ischemia/reperfusion. Shock 2005;24(5):462-469.

46. Sato N, Moore FA, Smith MA, Zou L, Olufemi-Moore S, Schultz SG, Kozar RA. Differential induction of PPAR{gamma} by luminal glutamine and iNOS by luminal arginine in the rodent post ischemic small bowel. Am J Physiol Gastrointest Liver Physiol. 2006 Apr; 290(4):G616-623. Epub 2005 Oct 27.

47. Kozar RA, Anderson KD. Surgical Education Research. J Surg Res. 2005 Oct;128(2):186-8.

48. Brundage SI, Lucci A, Miller CC, Azizzadeh A, Spain DA, Kozar RA. Potential targets to encourage a surgical career. J Amer Coll Surg. 2005; 200(6):946-953.

49. Tyroch AH, McGuire EL, McLean SF, Kozar RA, Gates K, Kaups KL, Cook C, Griswold JA, Sue LA, Craun M, Price J. The association of Chance Fractures and intra-abdominal injuries revisited: A multicenter review. Amer Surg. 2005;71(5):434-438.

50. Moore-Olufemi S, Kozar RA, Moore FA, Sato N, Hassoun HT, Cox CS, Kone BC. Ischemic preconditioning protects against gut dysfunction and mucosal injury after ischemia/reperfusion injury. Shock. 2005; 23: 258-263.

51. Sato N, Moore FA, Smith MA, Zou L, Moore-Olufemi S, Schultz SG, Kozar RA. Immune enhancing enteral nutrients differentially modulate the early pro-inflammatory transcription factors mediating gut ischemia/reperfusion. J Trauma. 2005 Mar; 58(3):455-461.

52. Todd SR, Kozar RA, Moore FA.Nutrition support in adult trauma patients. Nutrition in Clinical Practice. 2006 Oct; 21(5):421-9.

53. Todd SR, Holcomb JB, Kozar RA, Kao LS, McNally MM, Cocanour CS, Vercruysse GA, Lygas MH, Brasseaux BK, Moore FA. A multidisciplinary clinical pathway decreases rib fracture associated infectious morbidity and mortality in high risk trauma patients. Am J Surg. 2006 Dec;192(6):806-811.

54. Gonzalez EA, Kozar RA, Suliburk JW, Mercer DW, Moore FA. Conventional dose hypertonic-saline provides optimal gut protection and limits remote organ injury after

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gut ischemia/reperfusion. J. Trauma 2006 Jul;61(1):66-74. 55. Kosir R, SR Todd, Selby J, Cocanour C, Kozar RA, Vercruysse GA, Gonzalez E,

Ware N, Moore F. Acute lower extremity compartment syndrome (ALECS) screening. J Trauma. 2007 Aug; 63(2):268-275.

56. Kozar RA, Kao L, Miller CC, Schenarts K. Preclinical predictors of Surgery NBME Performance. J Surg Res. 2007 Jun 15; 140(2):204-207.

57. Gonzalez EA, Hunter R, Kozar RA, Moore FA. Poloxamer 188-Hypertonic saline provides optimal ileal protection after mesenteric ischemia/reperfusion. J Surg Res 2007;137; 337-338

58. Gonzalez EA, Moore FA, Holcomb JB, Miller CC, Kozar RA, Todd SR, Cocanour CS, McKinley BA. Fresh frozen plasma should be given earlier to patients who require massive transfusion. J Trauma. 2007 Jan;62(1):112-119.

59. Todd SR, Gonzalez EA, Turner K, Kozar, RA. Update on postinjury nutrition. Curr Opinions in Crit Care. 2008 Dec; 14(6):690-695.

60. Ban K, Kozar RA. Enteral glutamine: A novel mediator of PPARγ in the postischemic gut. J. Leuk Biol. 2008 Sep; 84(3):595-599.

61. Harting M, Jimenez F, Kozar RA, Moore FA, Mercer DW, Hunter RL, Cox CS, Gonzalez EA. Effects of Poloxamer 188 on human PMN cells. Surgery. 2008 Aug; 144(2);198-203.

62. Robinson EK, Kelly DP, Mercer DW, Kozar RA. Differential effects of luminal arginine and glutamine on metalloproteinase production in the postischemic gut. JPEN. 2008 Jul-Aug; 32(4);433-438.

63. Scott D, Cendan J, Pugh C, Minter R, Dunnington G, Kozar RA. The changing face of surgical education: Simulation as the new paradigm. J Surg Res. 2008 Jun 15; 147(2):189-93.

64. Suliburk J, Kao L, Kozar RA, Mercer DW. Training future surgical scientists: Realities and recommendations. Ann Surg. 2008 May; 247(5):741-9.

65. Kozar RA. Hypothermia hype: Is it worth it? Crit Care Med. 2008 May; 36(5):1676-7.66. Cocanour CS, Dial E, Lichtenberger L, Gonzalez EA, Kozar RA, Moore FA, Mercer

DW. Gastric Alkalinization following major trauma. J Trauma. 2008 Mar; 64(3):681-687.

67. Kozar RA, Shackford S, Cocanour CS. Challenges to the care of the critically ill: novel staffing paradigms. J Trauma. 2008 Feb; 64(2):366-370.

68. McQuigan M, Kozar RA, Moore FA. Enteral glutamine during active shock resuscitation is safe and enhances tolerance. JPEN. 2008 Jan-Feb 32(1):28-35.

69. Bick RJ, Poindexter BJ, Sheikh-Hamad D, Santora RJ, Kozar RA, Klein GA. Changes in the calcium-sensing receptor and stanniocalcin-1 in rat small intestine in response to ischemia-reperfusion injury. Current Trends in Protein and Peptide Research 2009 10:37-43.

70. Pati S , Matijevic N, Doursout MF, Ko T, Cao Y, Deng X, Kozar RA, Hartwell E, Conyers J, Holcomb JB. Protective effects of fresh frozen plasma on vascular endothelial permeability, coagulation, and resuscitation after hemorrhagic shock are time dependent and diminish between days 0 and 5 after thaw. J Trauma; 2010 Jul;69 Suppl 1:S55-63

Kozar RA

71. Santora R , Kozar RA. Molecular mechanisms of pharmaconutrients. J Surg Res. 2010 Jun 15;161(2):288-94. Epub 2009 Jul 17

72. Hunter RL , Luo AZ, Zhang R, Kozar RA, Moore FA. Poloxamer 188 inhibition of ischemia/reperfusion injury: evidence for a novel anti-adhesive mechanism. Ann Clin Lab Sci. 2010 Spring;40(2):115-25.

73. Kozar RA, Moore FA, Moore EE, West M, Cocanour CS, Davis J, Biffl WL, McIntyre RC, Jr. Western Trauma Association Critical Decisions in Trauma: Nonoperative Management of Adult Blunt Hepatic Trauma. J. Trauma; 2009 Dec, Vol 67(6), 1144-1148; discussion 1148-9

74. Biffl, WL, Cothren CC, Moore EE, Kozar RA, Cocanour CS, Davis JW, McIntyre RC, West MA, Moore FA. Western Trauma Association Critical Decisions in Trauma: Screening for and Treatment of Blunt Cerebrovascular Injuries. J. Trauma; 2009 Dec, Vol 67(6), 1150-1153.

75. McKinley BA, Sucher JF, Todd SR, Gonzalez EA, Kozar RA, Sailors RM, Moore FA. Central venous pressure versus pulmonary artery catheter-directed shock resuscitation. Shock. 2009 Nov; 32(5):463-70.

76. Moore-Olufemi SD, Olufemi SE, Lott S, Sato N, Kozar RA, Moore FA, Radhakrishnan RS, Shah S, Jimenez F, Kone BC, Cox CS Jr. Intestinal Ischemic Preconditioning After Ischemia/Reperfusion Injury in Rat Intestine: Profiling Global Gene Expression Patterns. Dig Dis Sci. 2010 Jul 55(7):1866-77. 2009 Sep 25. [Epub ahead of print]

77. Jastrow KM III, Gonzalez EA, McGuire MF, Suliburk JW, Kozar RA, Iyengar S, Motschall DA, McKinley BA, Moore FA, Mercer DW. Early Cytokine Production Risk Stratifies Trauma Patients for Multiple Organ Failure. Am Coll Surg. 2009 Sep; 209(3):320-31

78. Markell KW, Renz EM, White CE, Albrecht ME, Blackbourne LH, Park MS, Barillo DA, Chung KK, Kozar RA, Minei JP, Cohn SA, Herndon DN, Cancio LC, Holcomb JB, Wolf SE. Abdominal complications after severe burns. Am Coll Surg. 2009 May; 208(5):940-7; discussion 947-9.

79. McKinley BA, Sucher JF, Todd SR, Gonzalez EA, Kozar RA, Sailors RM, Moore FA. Central Venous Pressure vs. Pulmonary Artery Catheter Directed Shock Resuscitation. Shock, 2009 Apr15

80. Pati S, Matijevic N, Doursout MF, Ko T, Cao Y, Deng X, Kozar RA, Hartwell E, Conyers J, Holcomb JB. Protective effects of fresh frozen plasma on vascular endothelial permeability, coagulation, and resuscitation after hemorrhagic shock are time dependent and diminish between days 0 and 5 after thaw. 2010 Jul;69 Suppl 1:S55-63

81. Ban K , Santora R, Kozar RA. Enteral arginine modulates inhibition of AP-1/c-Jun by SP600125 in the postischemic gut. Mol Cell Biochem. 2011 347:191-9.2010 Oct 29. [Epub ahead of print]

82. Ban K , Kozar RA. Glutamine protects against apoptosis via down-regulation of Sp3 in intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2010 299:1344-53.2010 Sep 30. [Epub ahead of print]

83. Kozar RA, McNutt MK. Management of adult blunt hepatic trauma. Curr Opin Crit Care. 2010 Dec;16(6):596-601.

Kozar RA

84. Hatch QM , Osterhout LM, Podbielski J, Kozar RA, Wade CE, Holcomb JB, Cotton BA. Impact of closure at the first take back: complication burden and potential overutilization of damage control laparotomy. J Trauma. 2011 Dec;71(6):1503-11. PMID: 22182860

85. Ban K , Peng Z, Lin W, Kozar RA. Arginine decreases peroxisome proliferator-activated receptor-γ activity via c-Jun. Mol Cell Biochem. 2011 Oct 26. [Epub ahead of print] PMID: 22038625

86. Pati S , Gerber MH, Menge TD, Wataha KA, Zhao Y, Baumgartner JA, Zhao J, Letourneau PA, Huby MP, Baer LA, Salsbury JR, Kozar RA, Wade CE, Walker PA, Dash PK, Cox CS Jr, Doursout MF, Holcomb JB. Bone marrow derived mesenchymal stem cells inhibit inflammation and preserve vascular endothelial integrity in the lungs after hemorrhagic shock. PLoS One. 2011;6(9):e25171. Epub 2011 Sep 28. PMCID: PMC3182198.

87. Wade CE , del Junco DJ, Holcomb JB; Trauma Outcomes Group, Holcomb JB, Wade CE, Brasel KJ, Vercruysse G, MacLeod J, Dutton RP, Hess JR, Duchesne JC, McSwain NE, Muskat P, Johannigman J, Cryer HM, Tillou A, Cohen MJ, Pittet JF, Knudson P, De Moya MA, Schreiber MA, Tieu B, Brundage S, Napolitano LM, Brunsvold M, Sihler KC, Beilman G, Peitzman AB, Zenait MS, Sperry J, Alarcon L, Croce MA, Minei JP, Kozar R, Gonzalez EA, Stewart RM, Cohn SM, Mickalek JE, Bulger EM, Cotton BA, Nunez TC, Ivatury R, Meredith JW, Miller P, Pomper GJ, Marin B. Variations between level I trauma centers in 24-hour mortality in severely injured patients requiring a massive transfusion. J Trauma. 2011 Aug;71(2 Suppl 3):S389-93. PMID: [PubMed - in process]

88. Rowell SE , Barbosa RR, Diggs BS, Schreiber MA; Trauma Outcomes Group, Holcomb JB, Wade CE, Brasel KJ, Vercruysse G, MacLeod J, Dutton RP, Hess JR, Duchesne JC, McSwain NE, Muskat P, Johannigamn J, Cryer HM, Tillou A, Cohen MJ, Pittet JF, Knudson P, De Moya MA, Schreiber MA, Tieu B, Brundage S, Napolitano LM, Brunsvold M, Sihler KC, Beilman G, Peitzman AB, Zenait MS, Sperry J, Alarcon L, Croce MA, Minei JP, Kozar R, Gonzalez EA, Stewart RM, Cohn SM, Mickalek JE, Bulger EM, Cotton BA, Nunez TC, Ivatury R, Meredith JW, Miller P, Pomper J, Marin B. Specific abbreviated injury scale values are responsible for the underestimation of mortality in penetrating trauma patients by the injury severity score. J Trauma. 2011 Aug;71(2 Suppl 3):S384-8. PMID: 21814109 [PubMed - in process]

89. Rowell SE , Barbosa RR, Allison CE, Van PY, Schreiber MA; Trauma Outcomes Group, Holcomb JB, Wade CE, Brasel KJ, Vercruysse G, MacLeod J, Dutton RP, Hess JR, Duchesne JC, McSwain NE, Muskat P, Johannigamn J, Cryer HM, Tillou A, Cohen MJ, Pittet JF, Knudson P, De Moya MA, Schreiber MA, Tieu B, Brundage S, Napolitano LM, Brunsvold M, Sihler KC, Beilman G, Peitzman AB, Zenait MS, Sperry J, Alarcon L, Croce MA, Minei JP, Kozar R, Gonzalez EA, Stewart RM, Cohn SM, Mickalek JE, Bulger EM, Cotton BA, Nunez TC, Ivatury R, Meredith JW, Pomper P, Pomper GJ, Marin B. Gender-based differences in mortality in response to high product ratio massive transfusion. J Trauma. 2011 Aug;71(2 Suppl 3):S375-9. PMID: 21814107 [PubMed - in process

90. Barbosa RR , Rowell SE, Sambasivan CN, Diggs BS, Spinella PC, Schreiber MA;

Kozar RA

Trauma Outcomes Group, Holcomb JB, Wade CE, Brasel KJ, Vercruysse G, MacLeod J, Dutton RP, Hess JR, Duchesne JC, McSwain NE, Muskat P, Johannigamn J, Cryer HM, Tillou A, Cohen MJ, Pittet JF, Knudson P, De Moya MA, Schreiber MA, Tieu B, Brundage S, Napolitano LM, Brunsvold M, Sihler KC, Beilman G, Peitzman AB, Zenait MS, Sperry J, Alarcon L, Croce MA, Minei JP, Kozar R, Gonzalez EA, Stewart RM, Cohn SM, Mickalek JE, Bulger EM, Cotton BA, Nunez TC, Ivatury R, Meredith JW, Pomper GJ, Marin B. A predictive model for mortality in massively transfused trauma patients. J Trauma. 2011 Aug;71(2 Suppl 3):S370-4. PMID: 21814106 [PubMed - in process].

91. Barbosa RR , Rowell SE, Diggs BS, Schreiber MA; Trauma Outcomes Group, Holcomb JB, Wade CE, Brasel KJ, Vercruysse G, MacLeod J, Dutton RP, Hess JR, Duchesne JC, McSwain NE, Muskat P, Johannigamn J, Cryer HM, Tillou A, Cohen MJ, Pittet JF, Knudson P, De Moya MA, Schreiber MA, Tieu B, Brundage S, Napolitano LM, Brunsvold M, Sihler KC, Beilman G, Peitzman AB, Zenait MS, Sperry J, Alarcon L, Croce MA, Minei JP, Kozar R, Gonzalez EA, Stewart RM, Cohn SM, Mickalek JE, Bulger EM, Cotton BA, Nunez TC, Ivatury R, Meredith JW, Miller P, Pomper GJ, Marin B. Profoundly abnormal initial physiologic and biochemical data cannot be used to determine futility in massively transfused trauma patients. J Trauma. 2011 Aug;71(2 Suppl 3):S364-9. PMID: 21814105 [PubMed - in process]

92. Brown LM , Aro SO, Cohen MJ; Trauma Outcomes Group, Holcomb JB, Wade CE, Brasel KJ, Vercruysse G, MacLeod J, Dutton RP, Hess JR, Duchesne JC, McSwain NE, Muskat P, Johannigamn J, Cryer HM, Tillou A, Pittet JF, Knudson P, De Moya MA, Schreiber MA, Tieu B, Brundage S, Napolitano LM, Brunsvold M, Sihler KC, Beilman G, Peitzman AB, Zenait MS, Sperry J, Alarcon L, Croce MA, Minei JP, Kozar R, Gonzalez EA, Stewart RM, Cohn SM, Mickalek JE, Bulger EM, Cotton BA, Nunez TC, Ivatury R, Meredith JW, Miller P, Pomper GJ, Marin B. A high fresh frozen plasma: packed red blood cell transfusion ratio decreases mortality in all massively transfused trauma patients regardless of admission international normalized ratio. J Trauma. 2011 Aug;71(2 Suppl 3):S358-63. PMID: 21814104 [PubMed - in process]

93. Rowell SE , Barbosa RR, Diggs BS, Schreiber MA; Trauma Outcomes Group, Holcomb JB, Wade CE, Brasel KJ, Vercruysse G, MacLeod J, Dutton RP, Hess JR, Duchesne JC, McSwain NE, Muskat P, Johannigamn J, Cryer HM, Tillou A, Cohen MJ, Pittet JF, Knudson P, De Moya MA, Schreiber MA, Tieu B, Brundage S, Napolitano LM, Brunsvold M, Sihler KC, Beilman G, Peitzman AB, Zenait MS, Sperry J, Alarcon L, Croce MA, Minei JP, Kozar R, Gonzalez EA, Stewart RM, Cohn SM, Mickalek JE, Bulger EM, Cotton BA, Nunez TC, Ivatury R, Meredith JW, Miller P, Pomper GJ, Marin B. Effect of high product ratio massive transfusion on mortality in blunt and penetrating trauma patients. J Trauma. 2011 Aug;71(2 Suppl 3):S353-7. PMID: 21814103 [PubMed - in process]

94. Brasel KJ , Vercruysse G, Spinella PC, Wade CE, Blackbourne LH, Borgman MA, Zarzabal LA, Du F, Perkins JG, Maegele M, Schreiber M, Hess JR, Jastrow KM 3rd, Gonzalez EA, Holcomb JB, Kozar R; Trauma Outcomes Group, Brasel KJ, Vercruysse G, MacLeod J, Dutton RP, Duchesne JC, McSwain NE, Muskat P, Johannigamn J, Cryer HM, Cryer HM, Pittet JF, Knudson P, De Moya MA, Tieu B, Brundage S, Napolitano LM, Brunsvold M, Sihler KC, Beilman G, Peitzman AB, Zenait

Kozar RA

MS, Sperry J, Alarcon L, Croce MA, Minei JP, Stewart RM, Cohn SM, Mickalek JE, Bulger EM, Cotton BA, Nunez TC, Ivatury R, Meredith JW, Miller P, Pomper GJ, Marin B. The association of blood component use ratios with the survival of massively transfused trauma patients with and without severe brain injury. J Trauma. 2011 Aug;71(2 Suppl 3):S343-52. PMID: 21814102 [PubMed - in process]

95. Brown LM , Call MS, Margaret Knudson M, Cohen MJ; Trauma Outcomes Group, Holcomb JB, Wade CE, Brasel KJ, Vercruysse G, MacLeod J, Dutton RP, Hess JR, Duchesne JC, McSwain NE, Muskat P, Johannigamn J, Cryer HM, Tillou A, Pittet JF, De Moya MA, Schreiber MA, Tieu B, Brundage S, Napolitano LM, Brunsvold M, Brunsvold M, Beilman G, Peitzman AB, Zenait MS, Sperry J, Alarcon L, Croce MA, Minei JP, Kozar R, Gonzalez EA, Stewart RM, Cohn SM, Mickalek JE, Bulger EM, Cotton BA, Nunez TC, Ivatury R, Meredith JW, Miller P, Pomper GJ, Marin B. A normal platelet count may not be enough: the impact of admission platelet count on mortality and transfusion in severely injured trauma patients. J Trauma. 2011 Aug;71(2 Suppl 3):S337-42. PMID: 21814101 [PubMed - in process]

96. Sambasivan CN , Kunio NR, Nair PV, Zink KA, Michalek JE, Holcomb JB, Schreiber MA; Trauma Outcomes Group, Wade CE, Brasel KJ, Vercruysse G, MacLeod J, Dutton RP, Hess JR, Duchesne JC, McSwain NE, Muskat P, Johannigamn J, Cryer HM, Tillou A, Cohen MJ, Pittet JF, Knudson P, De Moya MA, Tieu B, Brundage S, Napolitano LM, Brunsvold M, Sihler KC, Beilman G, Peitzman AB, Zenait MS, Sperry J, Alarcon L, Croce MA, Minei JP, Kozar R, Gonzalez EA, Stewart RM, Cohn SM, Bulger EM, Cotton BA, Nunez TC, Ivatury R, Meredith JW, Miller P, Pomper GJ, Marin B. High ratios of plasma and platelets to packed red blood cells do not affect mortality in nonmassively transfused patients. J Trauma. 2011 Aug;71(2 Suppl 3):S329-36. PMID: 21814100 [PubMed - in process]

97. Holcomb JB , Zarzabal LA, Michalek JE, Kozar RA, Spinella PC, Perkins JG, Matijevic N, Dong JF, Pati S, Wade CE; Trauma Outcomes Group. Increased platelet:RBC ratios are associated with improved survival after massive transfusion. J Trauma. 2011 Aug;71(2 Suppl 3):S318-28. PMID: 21814099 [PubMed - in process]

98. Holcomb JB , Wade CE; Trauma Outcomes Group, Brasel KJ, Vercruysse G, MacLeod J, Dutton RP, Hess JR, Duchesne JC, McSwain NE, Muskat P, Johannigamn J, Cryer HM, Tillou A, Cohen MJ, Pittet JF, Knudson P, De Moya MA, Schreiber MA, Tieu B, Brundage S, Napolitano LM, Brunsvold M, Sihler KC, Beilman G, Peitzman AB, Zenait MS, Sperry J, Alarcon L, Croce MA, Minei JP, Kozar R, Gonzalez EA, Stewart RM, Cohn SM, Mickalek JE, Bulger EM, Cotton BA, Nunez TC, Ivatury R, Meredith JW, Miller P, Pomper GJ, Marin B. Defining present blood component transfusion practices in trauma patients: papers from the Trauma Outcomes Group. J Trauma. 2011 Aug;71(2 Suppl 3):S315-7. PMID: 21814098 [PubMed - in process]

99. Cotton BA , Reddy N, Hatch QM, Lefebvre E, Wade CE, Kozar RA, Gill BS, Albarado R, McNutt MK, Holcomb JB. Damage control resuscitation is associated with a reduction in resuscitation volumes and improvement in survival in 390 damage control laparotomy patients. Ann Surg. 2011 Oct;254(4):598-605. PMID: 21918426 [PubMed - in process]

100. Haywood-Watson RJ, Holcomb JB, Gonzalez EA, Peng Z, Pati S, Park PW, Wang

Kozar RA

WW, Zaske AM, Menge T, Kozar RA. Modulation of Syndecan-1 shedding after hemorrhagic shock and resuscitation. PLoS ONE 2011;6(8):e23530. Epub 2011 Aug 19. PMCID: PMC3158765

101. Cotton BA , Faz G, Hatch QM, Radwan ZA, Podbielski J, Wade C, Kozar RA, Holcomb JB. Rapid thrombelastography delivers real-time results that predict transfusion within 1 hour of admission. J Trauma. 2011 Aug;71(2):407-17. PMID: 21825945 [PubMed - in process]

102. Cotton BA , Kao LS, Kozar R, Holcomb JB. Cost-utility analysis of levetiracetam and phenytoin for posttraumatic seizure prophylaxis. J Trauma. 2011 Aug;71(2):375-9. PMID: 21825941 [PubMed - in process]

103. Kozar RA , Feliciano DV, Moore EE, Moore FA, Cocanour CS, West MA, Davis JW, McIntyre RC Jr. Western Trauma Association/Critical Decisions in Trauma: Operative Management of Adult Blunt Hepatic Trauma. J Trauma. 2011 Jul;71(1):1-5PMID: 21818009 [PubMed - as supplied by publisher]

104. Feliciano DV , Moore FA, Moore EE, West MA, Davis JW, Cocanour CS, Kozar RA, McIntyre RC Jr. Evaluation and Management of Peripheral Vascular Injury. Part 1. Western Trauma Association/Critical Decisions in Trauma. J Trauma. 2011 Jun;70(6):1551-1556. PMID: 21817992 [PubMed - as supplied by publisher]

105. Hatch QM , Osterhout LM, Ashraf A, Podbielski J, Kozar RA, Wade CE, Holcomb JB, Cotton BA. Current use of damage-control laparotomy, closure rates, and predictors of early fascial closure at the first take-back. J Trauma. 2011 Jun;70(6):1429-36. PMID: 21817992 [PubMed - as supplied by publisher]

106. Ban K , Sprunt JM, Martin S, Yang P, Kozar RA. Glutamine activates perxisome proliferator-activated receptor gamma in intestinal epithelial cells via 15-S-HETE and 13-OXO-ODE: A novel mechanism. Am J Physiol Gastrointest Liver Physiol. 2011 Jul 7. [Epub ahead of print]. PMID: 21737777 [PubMed - as supplied by publisher]

107. Zarzaur BL , Kozar RA, Fabian TC, Coimbra R. A survey of American Association for the Surgery of Trauma member practices in the management of blunt splenic injury. J Trauma. 2011 May;70(5):1026-31. PMID: 21610420 [PubMed - indexed for MEDLINE]

108. Duan C , Cao Y, Deng X, Wang W, Yang W, Liu X, Chen Z, Pati S, Kozar RA, Gonzalez EA, Wade CE, Holcomb JB, Ko TC. Increased TGF-β Contributes to Deterioration of Refrigerated Fresh Frozen Plasma's Effects in Vitro on Endothelial Cells. Shock 2011 36(1):54-59, Feb 15. [Epub ahead of print]

109. Kozar RA, Santora RJ, Poindexter BJ, Milner SM, Bick RJ. Alterations in content and localization of defensins in rat ileum and jejunum following ischemia-reperfusion. Specific peptides, in specific places, for specific jobs? ePlasty 2011 Feb 23;11:e8

110. Kozar RA, Peng Z, Zhang R, Holcomb JB, Pati S, Park P, Ko TC, Paredes A. Plasma restoration of endothelial glycocalyx in a rodent model of hemorrhagic shock. Anesth Analg. 2011 112:1289-1295.

111. Adams SD, Cotton BA, McGuire MF, Dipasupil E, Podbielski J, Zaharia A, Jastrow K, Ware DN, Gill BS, Albarado R, Kozar RA, Gonzalez EA, Duke JR, Adams PR, Dyer CB, Holcomb JB. The unique pattern of complications in elderly trauma patients at a Level 1 trauma center. J Trauma 2011 72(1):112-8.

Kozar RA

112. Matijevic N, Kostousov V, Wang YW, Wade CE, Wang W, Letourneau P, Hartwell E, Kozar R, Ko T, Holcomb JB. Multiple levels of degradation diminish hemostatic potential of thawed plasma. J Trauma. 2011 Jan;70(1):71-9; discussion 79-80.

113. Menge T, Zhao Y, Zhao J, Wataha K, Geber M, Zhang J, Letourneau P, Redell J, Shen K, Wang J, Peng Z, Xue H, Kozar R, Cox C, Khakoo AY, Holcomb H, Dash P, Pati S. Mesenchymal stem cells regulate blood brain barrier integrity in traumatic brain injury through production of the soluble factor TIMP3. Science Translational Medicine 2012, 21(4):161):161ra150.

114. Kwiatt ME , Patel MS, Ross SE, Lachant MT, Macnew HG, Ochsner MG, Norwood SH, Speier L, Kozar R, Gerber JA, Rowell S, Krishnakumar S, Livingston DH, Manis G, Haan JM. Is low-molecular-weight heparin safe for venous thromboembolism prophylaxis in patients with traumatic brain injury? A Western Trauma Association multicenter study. J Trauma Acute Care Surg. 2012 Sep;73(3):625-628. PMID: 22929493

115. Holcomb JB , Minei KM, Scerbo ML, Radwan ZA, Wade CE, Kozar RA, Gill BS, Albarado R, McNutt MK, Khan S, Adams PR, McCarthy JJ, Cotton BA. Admission rapid thrombelastography can replace conventional coagulation tests in the emergency department: experience with 1974 consecutive trauma patients. Ann Surg. 2012 Sep;256(3):476-86. PMID: 2286837

116. Ban K, Kozar RA. Protective Role of p70S6K in Intestinal Ischemia/Reperfusion Injury in Mice. PLoS One 2012;7(7):e41584. Epub 2012 Jul 27. PMID: 22848534

117. Peng Z, Ban K, Sen A, Grill R, Park PY, Costantini TW, Lin W, Kozar RA. Syndecan-1 plays a novel role in enteral glutamine’s gut protective effects of the post ischemic gut. Shock 2012 Jul 38(1):57-62. Epub May 2011 PMID: 22575998

118. Cotton BA, Minei KM, Radwan ZA, Matijevic N, Pivalizza E, Podbielski J, Wade CE, Kozar RA, Holcomb JB. Admission rapid thrombelastography predicts development of pulmonary embolism in trauma patients. J Trauma Acute Care Surg. 2012 Jun;72(6):1470-5; discussion 1475-7. PMID: 22695409

119. Michetti CP, Fakhry SM, Ferguson PL, Cook A, Moore FO, Gross R; AAST Ventilator-Associated Pneumonia Investigators. Ventilator-associated pneumonia rates at major trauma centers compared with a national benchmark: a multi-institutional study of the AAST. J Trauma Acute Care Surg. 2012 May;72(5):1165-73. PMID: 22673241

120. Podoll AS, Kozar R, Holcomb JB, Finkel KW. Incidence and outcome of early acute kidney injury in critically-ill trauma patients PLoS One 2013, 2013 Oct 17;8(10):e77376.

121. Ban K, Peng Z, Kozar RA. Inhibition of ERK ½ worsens intestinal ischemia/reperfusion injury. PLoS One 2013, Sep 20;8(9):e76790.

122. Moisey LL, Mourtzakis M, Cotton BA, Premji T, Heyland DK, Wade CE, Bulger E, Kozar RA. Skeletal muscle predicts ventilator-free days, ICU-free days, and mortality in elderly ICU patients. Critical Care 2013, Sep 19;17(5):R206. [Epub ahead of print]

123. Tilquist M, Leung R, Kutsogiannis J, Wischmeyer, P, Karvellas D, Preiser JC, Bird N, Kozar R, Heyland DK. Bedside ultrasound is a practical and reliable measurement tool for assessing quadriceps muscle layer thickness in the critically ill. JPEN J Parenter Enteral Nutr 2013, Oct;258(4):527-33.

Kozar RA

124. McClave SA, Kozar R, Martindale RG, Heyland DK, Braga M, Carli F, Drover JW, Flum D, Gramlich L, et al. Summary points and consensus recommendations from the North American Surgical Nutrition Summit. JPEN 2013, Sept;37(5 Suppl):99S-105S.

125. Pierre JF, Heneghan AF, Lawson SM, Wischmeyer PE, Kozar RA, Kudsk KA. Pharmaconutrition review: physiological mechanisms. JPEN 2013, Sept;37(5 Suppl):51S-65S.

126. Finnerty C Mabvuure N, Ali A, Kozar RA, Herdon D. Nutritional Supplementation of the surgically-induced stress response. JPEN 2013, Sept;37(5 Suppl):21S-9S.

127. Cotton BA, Podbielski J, Camp E, Welch T, Del Junco D, Bai Y, Hobbs R, Scroggins J, Hartwell B, Kozar RA, Wade CE, Holcomb JB. A Randomized Controlled Pilot Trial of Modified Whole Blood versus Component Therapy in Severely Injured Patients Requiring Large Volume Transfusions. Ann Surg. 2013 Oct;258(4):527-33.

128. Peng Z, Pati S, Potter D, Brown R, Holcomb JB, Grill R, Wataha K, Park PW, Xue H, Kozar RA. Fresh frozen plasma lessens pulmonary endothelial inflammation and hyperpermeability after hemorrhagic shock and is associated with loss of syndecan-1. Shock. 2013 40(3):195-202. Jun 25. [Epub ahead of print]

129. Adams SD, Cotton BA, Wade CE, Kozar RA, Dipasupil E, Pdbielski JM, Gill BS, Duke JR, Adams PR, Holcomb JB. Do not resuscitate status, not age, affects outcomes after injury: An evaluation of 15,227 consecutive trauma patients. J Trauma Acute Care Surg 2013, 74(5):1327-30.

130. Wataha K, Menge T, Deng X, Shah A, Bode A, Holcomb JB, Potter D, Kozar RA, Spinella PC, Pati S. Spray-dried plasma and fresh frozen plasma modulate permeability and inflammation in vitro in vascular endothelial cells. Transfusion 2013 53:Suppl 1:80S-90S.

131. Jenkins DH, Rappold JF, Badloe JF, Berséus O, Blackbourne L, Brohi KH, Butler FK, Cap AP, Cohen MJ, Davenport R, Depasquale M, Doughty H, Glassberg E, Hervig T, Hooper TJ, Kozar R, Maegele M, Moore EE, Murdock A, Ness PM, Pati S, Rasmussen T, Sailliol A, Schreiber MA, Sunde GA, van de Watering LM, Ward KR, Weiskopf RB, White NJ, Strandenes G, Spinella PC. THOR Position Paper on Remote Damage Control Resuscitation: Definitions, Current Practice and Knowledge Gaps. Shock. 2014 2014 May;41 Suppl 1:3-12.

132. Shackelford SR, Kahl JE, Calvo RY, Kozar RA, Haugen CE, Kaups KL, Willey M, Tibbs BM, Mutto SM, Rizzo AG, Lormel CS, Shackford MC, Burlew CC, Moore EE, Cogbill TH, Kallies KJ, Haan JM, Ward J. Gunshot wounds and blast injuries to the face are associated with significant morbidity and mortality: Results of an 11-year multi-institutional study of 720 patients. J Trauma Acute Care Surg. 2014 Feb;76(2):347-52.

133. Wade CE, Kozar RA, Dyer CB, Bulger EM, Mourtzakis M, Heyland DK. Evaluation of Nutrition Deficits in Adult and Elderly Trauma Patients. JPEN J Parenter Enteral Nutr. 2014 Feb 21. [Epub ahead of print]

134. Kozar RA, Holcomb JB, Xiong W, Nathens AB. Are all deaths created equally? The impact of hospice care on risk-adjusted mortality. J Trauma Acute Care Surg 2014 Mar;76(3):634-41.

135. Shalhub S, Starnes BW, Brenner ML, Biffl WL, Azizzadeh A, Inaba K, Skiada D, Zarzaur B, Nawaf C, Eriksson EA, Fakhry SM, Paul JS, Kaups KL, Ciesla DJ, Todd

Kozar RA

SR, Seamon MJ, Capano-Wehrle LM, Jurkovich GJ, Kozar RA. Blunt abdominal aortic injury: A Western Trauma Association multicenter study. J Trauma Acute Care Surg. 2014 Dec;77(6):879-85; discussion 885. 

136. Kozar R. What’s new in Shock? Shock. 2014 Dec;42(6):483-4137. Peng Z, Ban K, Wawrose RA, Gover A, Kozar RA. Protection by enteral glutamine is

mediated by intestinal epithelial cell peroxisome proliferator-activated receptor gamma during intestinal ischemia/reperfusion. Shock. 2015 Apr;43(4):327-33

138. McNutt MK, Chinapuvvula NR, Beckmann NM, Camp EA, Laney RW, West OC, Gill BS, Kozar RA, Cotton BA, Wade CE, Adams PR, Holcomb JB. Early Surgical Intervention for Blunt Bowel Injury: The Bowel Injury Prediction Score (BIPS). Journal of Trauma and Acute Care Surgery. 2015 78(1): 105-11.

139. Shrestha B, Holcomb JB, Camp EA, Del Junco DJ, Cotton BA, Albarado R, Gill BS, Kozar RA, Kao LS, McNutt MK, Moore LJ, Love JD, Tyson GH 3rd, Adams PR, Khan S, Wade CE. Damage-control resuscitation increases successful nonoperative management rates and survival after severe blunt liver injury J Trauma Acute Care Surg. 2015 Feb;78(2):336-41

140. Kozar RA, Pati S. Syndecan-1 restitution by plasma after hemorrhagic shock. J Trauma Acute Care Surg. 2015 Jun;78(6 Suppl 1):S83-6.

141. Potter DR, Baimukanova G, Keating SM, Deng X, Chu JA, Gibb SL, Peng Z, Muench MO, Fomin ME, Spinella PC, Kozar R, Pati S.Fresh frozen plasma and spray-dried plasma mitigate pulmonary vascular permeability and inflammation in hemorrhagic shock. J Trauma Acute Care Surg. 2015 Jun;78(6 Suppl 1):S7-S17. 

142. Camazine MN, Hemmila MR, Leonard JC, Jacobs RA, Horst JA, Kozar RA, Bochicchio GV, Nathens AB, Cryer HM, Spinella PC.Massive transfusion policies at trauma centers participating in the American College of Surgeons Trauma Quality Improvement Program. J Trauma Acute Care Surg. 2015 Jun;78(6 Suppl 1):S48-53.

143. Kozar RA, Arbabi S, Stein D, Shackford SR, Barraco RD, Biffl WL, Brasel KJ, Cooper Z, Fakhry SM, Livingston D, Moore FA, Luchette F. Injury in the aged: Geriatric trauma care at the crossroads. J Trauma Acute Care Surg. 2015, Jun;78(6):1197-209

144. Ban K, Peng Z, Pati S, Witkov RB, Park PW, Kozar RA. Plasma-mediated gut protection after hemorrhagic shock is lessened in syndecan-1-/- mice. Shock. 2015 Nov;44(5):452-7Aug 10.

145. Deng X, Cao Y, Huby MP, Duan C, Baer L, Peng Z, Kozar RA, Doursout MF, Holcomb JB, Wade CE, Ko TC. Adiponectin in Fresh Frozen Plasma Contributes to Restoration of Vascular Barrier Function After Hemorrhagic Shock. Shock. January 2016 45(1):5-54. 2015 Aug 10 [Epub ahead of print]

146. Zarzaur BL, Kozar R, Myers JG, Claridge JA, Scalea TM, Neideen TA, Maung AA, Alacon L, Corcos A, Kerwin A, Coimbra R. The splenic injury outcomes trial: An American Association for the Surgery of Trauma multiinstitutional study. J Trauma Acute Care Surg 2015 Sept; 79(3):335-42.

147. Kutcher ME, Weis JJ, Siada SS, Kaups KL, Kozar RA, Summers JI, Eriksson EA, Leon SM, Carrick MM, Mallory G, Sperry JL. The role of computed tomographic scan in ongoing triage of operative hepatic trauma: A Western Trauma Association multicenter retrospective study. J Trauma Acute Care Surg. 2015 76(9):951-6. Sept 2 [Epub ahead of print]

Kozar RA

148. Moore LJ, Brenner M, Kozar R, Pasley J, Wade CE, Baraniuk MS, Scalea T, Holcomb JB. Implementation of resuscitative endovascular balloon occlusion of the aorta as an alternative to resuscitative thoracotomy for noncompressible truncal hemorrhage J Trauma Acute Care Surg. 2015 Oct;79(4):523-32.

149. Matijevic N, Wang YW, Holcomb JB, Kozar R, Cardenas JC, Wade CE. Microvesicle phenotypes are associated with transfusion requirements and mortality in subjects with severe injuries. J Extracell Vesicles. 2015 Dec 17;4:29338. doi: 10.3402/jev.v4.29338. eCollection 2015.

150. Bruns B, Kozar RA. Feeding the Postoperative Patient on Vasopressor Support: Feeding and Pressor Support. Nutr Clin Pract. 2016 Feb;31(1):14-7. doi: 10.1177/0884533615619932. Epub 2015 Dec 24.

151. Paris MT, Mourtzakis M, Day A, Leung R, Watharkar S, Kozar R, Earthman C, Kuchnia A, Dhaliwal R, Moisey L, Compher C, Martin N, Nicolo M, White T, Roosevelt H, Peterson S, Heyland DK. Validation of Bedside Ultrasound of Muscle Layer Thickness of the Quadriceps in the Critically Ill Patient (VALIDUM Study): A Prospective Multicenter Study. JPEN J Parenter Enteral Nutr. 2016 Mar 9.

152. Pusateri AE, Given MB, Schreiber MA, Spinella PC, Pati S, Kozar RA, Khan A, Dacorta JA, Kupferer KR, Prat N, Pidcoke HF, Macdonald VW, Malloy WW, Sailliol A, Cap AP. Dried plasma: state of the science and recent developments. Transfusion. 2016 Apr;56 Suppl 2:S128-39.

153. Bruns BR, Ahmad SA, O’Meara L, Tesoriero R, Lauerman M, Klyushnenkova E, Kozar R, Scalea TM, Diaz JJ. Non-Trauma Open Abdomens: A Prospective Observational Study. J Trauma Acute Care Surg. 2016 Apr;80(4):631-6. 

154. Peng Z, Ban K, LeBlanc A, Kozar RA. Intraluminal Tranexamic Acid Inhibits Intestinal Sheddases and Mitigate Gut and Lung Injury and Inflammation in a Rodent Model of Hemorrhagic Shock. J Trauma Acute Care Surg. 2016 Aug;81(2):358-65.  154.

155. McDonald D, Ackermann G, Khailova L, Baird C, Heyland D, Kozar R, Lemieux M, Derenski K, King J, Vis-Kampen C, Knight R, Wischmeyer PE. Extreme dysbiosis of the microbioime in critical illness. mSphere. 2016 Aug 31;1(4). pii: e00199-16. doi: 10.1128/mSphere.00199-16.

156. Kozar RA, Sanddal ND. Role of level IV trauma centers in an inclusive trauma system: the injured elderly. Am J Surg. 2016 Sep;212(3):377-8.

157. Moisey LL, Mourtzakis M, Kozar RA, Compher C, Heyland DK. Existing equations to estimate lean body mass are not accurate in the critically ill: Results of a multicenter observational study. Clin Nutr. 2016 Sep 23. pii: S0261-5614(16)31251-1.

158. Jenkins DH, Winchell RJ, Coimbra R, Rotondo MF, Weireter LJ, Bulger EM, Kozar RA, Nathens AB, Reilly PM, Henry SM, Jimenez MF, Chang MC, Coburn MC, Dodd J, Neal ML, Rosen J, Clemency J, Hoyt DB, Stewart RM; American College of Surgeons Committee on Trauma. Position statement of the American College of Surgeons Committee on Trauma on the National Academies of Sciences, Engineering and Medicine report, A National Trauma Care System: Integrating Military and Civilian Trauma Systems to Achieve Zero Preventable Deaths after Injury. Trauma Acute Care Surg. 2016 Nov;81(5):819-823. PubMed PMID: 27533902.

159. Peng Z, Pati S, Fontaine MJ, Hall K, Herrera AV, Kozar RA. Lack of Species Specific Difference in Pulmonary Function When Using Mouse Versus Human Plasma in a

Kozar RA

Mouse Model of Hemorrhagic Shock. J Trauma Acute Care Surg. 2016 2016 Nov;81(5 Suppl 2): 171-176.

160. Coimbra R, Kozar RA, Smith JW, Zarzaur BL, Hauser CJ, Moore FA, Bailey JA, Valadka A, Jurkovich GJ, Jenkins DH, Davis KA, Price MA, Maier RV. The Coalition for National Trauma Research (CNTR) Supports the Call for a National Trauma Research Action Plan. J Trauma Acute Care Surg. 2016 Dec 23. [Epub ahead of print]

161. Wu F, Peng Z, Park PW, Kozar RA. Loss of syndecan-1 abrogates the pulmonaryprotective phenotype induced by plasma after hemorrhagic shock. Shock. 2017 Jan 19. [Epub ahead of print]

Book Chapters

1. Kozar RA, Roslyn JJ: Appendix. In Schwartz SI (Ed.): Principles of Surgery, 7th edition. McGraw-Hill, Inc., 1999: 1383-1394.

2. Kozar RA, Cipolla J: Chylothorax. In Plantz S (Ed): Medicine, Ob/Gyn, Psychiatry, and Surgery. On-line reference text. (http://www.emedicine.com). Boston Medical Publishers.

3. Kozar RA, McQuiggan MM, Moore FA. Nutritional Support of Trauma Patients. In Shikora SA, Martindale RG, Schwaitzberg SD (Eds.): Nutritional Considerations in the Intensive Care Unit. Science, Rationale, and Practice. Kendall/Hunt Publishing Co., Dubuque, IO, 2002:229-244.

4. Kozar RA, Moore FA,: Postinjury Multiple Organ Failure. In Moore EE, Feliciano DV, Mattox KL (Eds.): Trauma Handbook, 4th edition. McGraw-Hill, Inc., 2002: (56) 501-506.

5. Kozar RA, Haenel JB, Moore FA. Flail Chest and Pulmonary Contusion. In Parsons PE, Wiener-Kronish JP (Eds.): Critical Care Secrets, 3rd edition, Lippincott, 2003: 403-408 and 4th edition, 2007: 447-451.

6. Kozar RA, McQuiggan MM, Moore FA. Trauma. In Rolandelli R (Ed): Clinical Nutrition (Volume I): Enteral and Tube Feeding, 4th edition, Saunders, 2004:364-372.

7. Kozar RA, McQuiggan MM, Moore FA. Trauma. In Merritt R (Ed): A.S.P.E.N. Nutrition Support Practice Manual, 2nd Edition, ASPEN, 2005:271-276.

8. Kozar RA, McQuiggan MM, Moore FA. Trauma In Cresci G (Ed): Nutrition Support in the Critically Ill Patient: A Guide to Practice, CRC Press, 2005:421-434.

9. Kozar RA, Moore FA. Fluid and Electrolyte Management of the Surgical Patient. In Brunicardi FC (Eds): Schwartz’s Principles of Surgery, 8th edition, McGraw-Hill, 2005;43-59.

10. Kozar RA, McQuiggan MM, Moore FA. Surgical Nutrition. In Miller T (Ed): Modern Surgical Care: Physiologic Foundations and Clinical Applications, 3rd Edition, Informa Healthcare, 2006: 49-64.

11. Kozar RA, Weisbrodt NW, Moore FA. Gut Failure in the Critically Injured Patient. In Feliciano DV, Mattox KL, Moore EE (Eds): Trauma, 6th edition, McGraw-Hill, 2008:1281-1290.

12. Gonzalez EA, Jastrow KM, Holcomb JB, Kozar RA. Hemostasis, Surgical Bleeding, and Transfusion. In Schwartz’s Principles of Surgery, 9th Edition, McGraw-Hill, 2009:67-87

13. Bick1 RJ, Poindexter BJ, Sheikh-Hamad D, Santora RJ, Kozar RA, Klein GL. Changes

Kozar RA

in the calcium-sensing receptor and stanniocalcin-1 in rat small intestine in response to ischemia-reperfusion injury. Current Topics in Peptide & Protein Research. 2010

14. Kozar RA, Moore FA. Gastrointestinal Failure in the Critically Injured Patient. In Feliciano DV, Mattox KL, Moore EE (Eds): Trauma, 7th edition, McGraw-Hill, 2012, 1073-1083.

15. Sixta S, Kozar RA. Management of the Severely Injured Trauma Patient. In Comprehensive Critical Care: Adult. Roberts PR, Todd SR (Eds). Society of Critical Care Medicine, 2012:805-821.

16. Schwartz D, Kozar RA. Nutrition in the Surgical Patient. In Moore LJ, Turner KL. Todd SR (Eds): Common Problems in Acute Care Surgery. Springer, New York, 2013, 119-129.

17. Kozar RA, McNutt MK. Disorders of Calcium and Magnesium Metabolism. In Textbook of Critical Care. 6th edition. Shoemaker. Part 6; 112 page 865. 2012

18. Gordy S, Kozar RA. Metabolism in the Trauma Patient. In Surgical metabolism: the Metabolic Care of the Surgical Patient. Davis K and Rosenbaum S (Eds); Springer, 2014.

19. Cotton B, Holcomb JB, Pommering M, Jastrow KM, Kozar RA. Hemostasis, Surgical Bleeding, and Transfusion. In Schwartz’s Principles of Surgery, 10 th Edition, McGraw-Hill, 2014, page 85-107.

20. Kozar RA, McNutt MK. Liver Injury Severity Score. Encyclopedia of Critical Care Medicine. 2014.

21. Kozar RA, McNutt MK. Disorders of Calcium and Magnesium Metabolism. In Textbook of Critical Care. 7th edition. Shoemaker. Chapter 108, 2016, in press.

22. Bruns B, Kozar RA. Liver and Biliary Tract. In Feliciano DV, Mattox KL, Moore EE (Eds): Trauma, 8th edition, McGraw-Hill, 2015, in press.

23. Berry C, Kozar RA. Solid Organ Injury. In Trauma Geriatrics 2nd edition, 2015, in press.24. Schwartz D, Tannous A, Kozar RA. Nutrition in the Surgical Patient. In Moore LJ,

Turner KL. Todd SR (Eds): Common Problems in Acute Care Surgery, 2nd edition. Springer, New York, 2016, in press.

25. Sixta S, Kozar RA. Management of the Severely Injured Trauma Patient. In Comprehensive Critical Care: Adult. Roberts PR, Todd SR (Eds). Society of Critical Care Medicine, 2nd edition 2016, in press.

Published Abstracts

1. Kozar RA, Abedin ZR, Abedin MZ, Trooskin SZ. Expression of epidermal growth factor in Type II Pneumocytes: A potential mechanism for recovery from acute lung injury. Investigative Medicine. 1998; 463 (3):223A.

2. Hassoun HT, Weisbrodt NW, Kozar RA, Mercer DW, Moody FG, Moore FA. Inducible nitric oxide synthase mediates impaired small intestinal transit after severe gut ischemia/reperfusion. J Surg Res. 2000; 91 (2): 353.

3. Kozar RA, Kaplan LJ, Cipolla J, Meija J, Haber M. Laparoscopic repair of traumatic diaphragmatic injuries. J Surg Res. 2000; 91(2):358-359.

4. Kozar RA, Schultz SG, Weisbrodt N, DeSoignie R, Hassoun HT, Moore FA. Intraluminal nutrients enhance gut ischemia/reperfusion injury. Shock. 2000; 13

Kozar RA

supp;28.5. Kozar RA, Moore EE, Kudsk K, Jurkovich G, Moore FA. Enteral tolerance following

severe trauma is reliably achieved by a standardized protocol. J Surg Res. 2001; 100 (2):292-293.

6. Kozar RA, Schultz SG, Hassoun HT, DeSoignie R, Moore FA. Intraluminal nutrients alter gut permeability following gut ischemia/reperfusion. Shock 2001;15 supp:65.

7. Von Maszewski M, Cocanour CS, McKinley B, Kozar RA, DeSoignie R, Weisbrodt N,Moore FA. MMC’s exist after trauma and predict enteral tolerance. J Trauma 2001; 50 (1):178.

8. Kozar RA, Hu S, Schultz SG, Hassoun HT, Moore FA. Specific enteral nutrients alter mucosal blood flow during gut ischemia/reperfusion. JPEN 2001; 25 (1):S11.

9. Kozar RA, Lucci A, Azzizadeh A, Miller CC, Cocanour CS, Potts J, Fischer C, Brundage SI. A brief intervention by surgeons can influence medical students towards a career in surgery. J Surg Res. 2002; 107 (4): 268.

10.Kozar RA, Holcomb JB, Macatis J, DeSoignie R, Moore FA. Superior mesenteric artery occlusion (SMAO) models shock-induced gut Ischemia/reperfusion. J Surg Res. 2002;107 (P55): 321.

11. Attuwaybi BO, Hassoun H, Kozar RA, Moore FA. Hypothermia protects against gut ischemia-reperfusion (I/R) induced impaired intestinal transit by inducing impaired intestinal transit by inducing heme oxygenase-1 (HO-1). J Surg Res. 2002; 107 (81): 294.

12.Balogh Z, McKinley BA, Holcomb JB, Miller CC, Cocanour CS, Kozar RA, Moore FA. Both primary and secondary abdominal compartment syndrome can be predicted early and are harbingers of bad outcome. J Trauma. 2002;53(1):198.

13.McKinley BA, Cocanour CS, Kozar RA, Ware DN, Sailors RM, Marquez A, Moore FA. Normal vs supranormal O2 delivery goals in shock resuscitation: the response is the same. J Trauma 2002; 53(1): 825-832.

14.Holcomb JB, McMullin NR, Kozar RA, Lygas MH, Macaitis JM, Moore FA. Morbidity from rib fractures increases after age 45. J Trauma. 2002; 52 (1):200.

15.Kozar RA, Anderson K, Chaves-Escobar S, Theil M, Brundage S. Preclinical students who are surgeons? J Surg Res. 2003; 114 (2):259.

16.Attuwaybi B, Kozar RA, Moore-Olufemi S, Sato N, Weisbrodt N, Hassoun H, Moore FA.Heme-oxygenase-1 (HO-1) induction by hemin protects against gut ischemia/reperfusion injury. J Surg Res. 2003; 114 (2):289.

17.Sato N, Kozar RA, Zou L, Moore-Olufemi S, Weisbrodt NW, Moore FA. Cyclooxygenase-2 (COX-2) plays a role in mediating impaired internal transit after gut ischemia/reperfusion (I/R). J Surg Res. 2003; 114 (2):287.

18.Attuwaybi B, Kozar RA, Sato N, Moore-Olufemia S, Weisbrodt NW, Moore FA. Hypertonic saline prevents inflammation and impaired intestinal transit after gut ischemia/reperfusion by inducing heme oxgenase 1(H0-1) enzyme. J Trauma 2003; 55(1): 205.

19.Kozar RA, Schultz SG, Bick R, DeSoignie R, Moore FA. Metabolizable solutes maintain integrity of the actin cytoskeleton and membrane barrier function following mesenteric ischemia/reperfusion. Shock. 2003; (19):217.

Kozar RA

20.Moore-Olufemia S, Kozar RA, DeSoignie R, Attuwaybi B, Gates K, Moore FA. Hypertonic saline enhances mucosal blood flow and lessens mucosal injury following gut ischemia/reperfusion. Shock. 2003; 19: 200.

21.Attuwaybi BO, Kozar RA, Moore-Olufemi S, Gates K, Hassoun HT, Moore FA. Hypertonic saline induces HO-1 expression and abrogates gut inflammation and dysfunction following shock-induced gut ischemia/reperfusion. Shock. 2003; 19:194.

22.Marr AB, McKinley BA, Sailors RM, Valdivia A, Kozar RA, Cocanour CS, Moore FA. Starling curve generation during shock resuscitation: Can it be done? Shock. 2003; 19:78.

23.Cocanour CS, Weisbrodt N, Kozar RA, Messick C, Moore FA. Gastric emptying following traumatic shock. Shock. 2003; 19:18.

24.Cocanour CS, Dial ED, Kozar RA, Lichtenberger LM, Messick C, Moore FA. Gastric Alkalinization following major trauma. J Trauma.2003;54(1):211.

25.Suliburk JW, Ware DN, Balogh Z, McKinley BA, Cocanour CS, Kozar RA, Moore FA. Vacuum assisted wound closure (VAWC) allows for early abdominal fascial closure in severely injured trauma patients requiring aggressive resuscitation. J Trauma. 2003; 54(1):207.

26.Domonoske B, Cocanour C, Valdivia A, Kozar, RA, Pousman R, Moore F.Aggressive Glucose Control: Implementation in an ICU. Critical Care Medicine. 2003;451: A108.

27.Gonzalez EA, Kozar RA, Suliburk JW, Moore FA, Mercer DW. The isomeric composition of Lactated Ringer’s has no differential effect of gastric dysfunction after mesenteric ischemia/reperfusion. J Surg Res. 2004;121:334.

28.Moore-Olufemi, Kozar RA, Moore FA, Hassoun HT, Sato N, Cox CS, Kone BC.Ischemic preconditioning protects against intestinal ischemia/reperfusion injury. Shock. 2004; 21:179.

29.Gonzalez E, Kozar RA, Suliburk J, Mercer D, Moore FA. Presence of D-Lactate increases ileal mucosal injury after mesenteric ischemia/reperfusion. Shock. 2004; 21:172.

30.McKinley B, Gonzalez E, Balldin B, Majid T, Valdivia A Cocanour CS, Kozar RA.Revisiting the “Bloody Vicious Cycle. Shock. 2004; 21:137.

31.Sato N, Kozar RA, Smith M, Zou L, Moore-Olufemi S, Schultz SG, Moore FA. Immune enhancing enteral agents differentially modulate the early pro-inflammatory transcription factors mediating gut ischemia/reperfusion. J Trauma. 2004; 57(2):449.

32.Kozar RA, Schultz SG, Verner-Cole E, Bick R, DeSoignie R, Poindexter B, Moore FA. Enternal arginine, an immune enhancing agent, impair gut barrier function following mesenteric ischemia/reperfusion. J Trauma. 2004; 56 (2):463.

33.Moore FA, Hassoun HT, Kozar RA, Weisbrodt NW. Shock Induced Ileus: Issues and consequences. Shock. 2004; 21:82.

34.Gonzalez EA, Kozar RA, Suliburk JW, Mercer DW, Moore FA. Conventional dose hypertonic-saline provides optimal immunodulation. J. Trauma. 2005;59(2) 532.

35.Gonzalez EA, Kozar RA, Suliburk JW, Mercer DW, Moore FA. Low volume hypertonic saline abrogates mesenteric ischemia/reperfusion induced remote organ injury. J. Trauma. 2005;59(2) 532.

Kozar RA

36.N Sato, Childs MA, Moore FA, Zou L, Kone BC, Schultz SG, Kozar RA. GW9662 inhibition of PPAR abrogates the protective function of enteral glutamine. Shock. 2005;23:51.

37.Sato N, Zou L, Attuwaybi B, Kozar RA, Moore FA, Kone BC. Alpha-melanocyte stimulating hormone preserves HO-1 expression induced by postischemic gut injury in rats. Gastroenterology 2005;4(suppl 2):A658.

38.McKinley BA, Balogh Z, Kozar RA, Valdiva A, Moore FA. GI tonometry is a monitor of onset of ACS. Shock. 2005;23:69.

39.Gonzalez E, Kozar RA, Suliburk J, Mercer D, Moore F. Hypertonic saline abrogates mesenteric ischemia/reperfusion. Shock. 2005 23, suppl 3, 31.

40.Gonzalez EA, Kozar RA, Suliburk JW, Tweardy DJ, Mercer DW, Moore FA. Hypertonic saline resuscitation after mesenteric ischemia/reperfusion induces ileal apoptosis via cytochrome C pathway. J Trauma. 2005;58(1): 215

41.Kozar RA, Moore JB, Miles SE, Holcomb JH, Moore EE, Cothern C, Moore FA. Complications of nonoperative management of high grade blunt hepatic injuries. J Trauma. 2005;58(1):222.

42.Gonzalez EA, Hunter R, Kozar RA, Weisbrodt N, Field E, Moore FA.Poloxamer 188 resuscitation after mesenteric ischemia/reperfusion abrogates neutrophil mediated ileal mucosal injury. Journal of Trauma. 2006;61:514.

43.McKinley B, Gonzalez E, Todd SR, Sucher J, Vercruysee G, Kozar RA, Cocanour C, Ware N, Motschall D, Sailors M, Moore FA. Mis-triage to central venous pressure directed resuscitation is associated with poor outcome. Shock. 2006;25:88.

44.Kozar R, SR Todd, Selby J, Cocanour C, Kozar RA, Vercruysee, Gonzalez E, Ware N, Moore F. Acute lower extremity compartment syndrome (ALECS) screening. J Trauma. 2006 60;251.

45.Moore-Olufemi SD, Lott S, Olufemi S, Sato N, Kozar RA, Moore FA, Radhakrishna RS, Cox CS, Kone BC. Transcriptional profiling of ischemic preconditioning in rat intestine following ischemia/reperfusion injury. JACS. 2006;203(3):S45

46.Gonzalez EA, Moore FA, Holcomb JB, Miller CC, Kozar RA, Todd SR, Cocanour CS, McKinley BA. Fresh frozen plasma should be given earlier to patients who require massive transfusion. J Trauma. 2006; 60:258.

47.Sato N, Moore FA, Zou L, Kozar RA. Reactive Oxygen species promotes TNF-alpha induced cytotoxicity in IEC-6 cells. J Surg Res. 2006;130:330.

48.Ban K, Gonzalez EA, Kone BC, Kozar RA. Enteral arginine modulates the effect of pharmacologic inhibition of AP-1 on iNOS in the postischemic gut. Shock. 2007;27(S1):78.

49.Moore-Olufemi SD, Moore FA, Gonzalez EA, Ban K, Fields E, Kone BC, Kozar RA. Transcriptional profiling of hypertonic saline in rat small intestine. Shock. 2007;27(S1):79.

50.McKinley B, Gonzalez E, Kozar R, Todd R, Ware N, Sailors M, Moore F. Central venous pressure vs pulmonary artery catheter directed shock. Shock. 2007;27(S1):56.

51.Kozar RA, Kao LS, Miller CC, Schenarts KD. Preclinical predictors of surgery shelf exam performance. J Surg Res 2007; 137:(2)159.

52.Gonzalez EA, Hunter R, Kozar RA, Moore FA. Poloxamer 188-Hypertonic saline

Kozar RA

provides optimal ileal protection after mesenteric ischemia/reperfusion. J Surg Res. 2007;137:337.

53.McQuiggan M. Kozar R, Sailors M, McKinley B, Weisbrodt N., Moore F. Techniques for determining gastric residual volume: is never better? JPEN.2008;32:341.

54.Gonzalez EA, Zhang R, Kozar RA, Moore FA, Hunter RL. Poloxamer hypotensive resuscitation. Shock. 2008;28(S1)8-9.

55.Ban K, Sprunt JM, Kozar RA. Glutamine: A novel ligand dependent activator of PPARγ. Shock. 2008;28(S1)56.

56.Harting MT, Jimenez F, Kozar RA, Moore FA, Mercer DW, Hunter R, Cox CS, Gonzalez EA. Direct effects of poloxamer 188 on human PMN cells. J Surg Res. 2008. 144;214.

57.Gonzalez EA, Mercer DW, Kozar RA. Isovolemic plasma resuscitation during shock. J Surg Res. 2008; 144, (2):432

58.Deng X, Cao Y, Pati S, Kozar RA, Holcomb JB, Ko TC. Fresh Frozen Plasma Activates Kinase Pathways in Endothelial Cells. Shock 2009, Vol. 31, (S1), 34.

59.Matijevic N, Wang W, Pati S, Kozar R, Conyers J, Holcomb J. Phenotypic Assessment of Cellular Microparticles in Fresh Frozen Plasma During Storage. Shock 2009, Vol. 31, (S1), 36.

60.Kozar R, R. Zhang, J. Holcomb, J. Sondeen, E. Gonzalez, S. Pati, T. Ko, J.F. Dong, A. Paredes. Plasma Restoration of Endothelial Glycocalyx After Hemorrhagic Shock. Shock 2009 Vol. 31, (S1), 49.

61.Holcomb J, Gerber M, Kozar R, Parthasarthy R, Matijevic N, Doursout MF, Ko T, Hartwell B, Conyers J, Pati S. Protective Effects of Plasma (FFP) on Pulmonary and Lymphatic Endothelial Permeability Diminishes Between Day 0 Through Day 5 After Thaw. Shock 2009 Vol. 31, (S1), 52.

62.E. Gonzalez, S. Pati, R. Kozar, B. Hartwell, J. Conyers, J. Holcomb. Effect of Activated Human Plasma on Syndecan-1 Expression. Shock 2009 Vol. 31, (S1), 55.

63.Y. Cao, X. Deng, X. Liu, S. Pati, R.A. Kozar, E.A. Gonzalez, J.B. Holcomb, T.C. Ko. Standard Storage of Fresh Frozen Plasma Increases TGF-β/SMAD3 Signaling. Shock 2009 Vol. 31, (S1), 56.

64.Ban K, Kozar RA. PPARγ mediates the regulation of INOS expression by C-JUN/AP-1. Shock 2010, Vol 33, (S1), 34.

65.Matijevis N, Wang Y-W W, Kozar RA, Gonzalez EA, Holcomb JB. Low levels of latelet microparticles correlate with poor outcomes in shock patients. Shock 2010, Vol 33, (S1), 45.

66.Deng X, Cao Y, Doursout MF, He G, Kozar RA, Holcomb JB, Ko TC. Standard storage of fresh frozen plasma (FFP) reduces its anti-apoptotic effects during hemorrhagic shock (HS) resuscitation. Shock 2010, Vol 33, (S1), 49.

67.Duan C, Cao Y, Deng X, Yang W, Kozar RA, Gonzalez EA, Holcomb JB, Ko TC. Plasma adiponectin levels decrease after hemorrhagic shock (HS). Shock 2010, Vol 33, (S1), 49.

68.Peng Z, Haywood-Watson, Pati S, Dong J, Vijayan V, Holcomb JB, Ko T, Kozar RA. Restitution of syndecan-1 is modulated by age of fresh frozen plasma (FFP). Shock

Kozar RA

2010, Vol 33, (S1), 61. 69.Haywood-Watson R 2nd, Pati S, Kozar R, Faz G, Holcomb J, Gonzalez E. Human

micro-vascular barrier disruption after hemorrhagic shock. J Surg Res. 2010 Feb;158(2):313.

70.Santora RJ, Medhus KA, Pati S, Holcomb JB, Kozar RA. Fresh plasma reverses hypoxia induced endothelial cell dysfunction. J Surg Res. 2010 Feb;158(2):296

71.Brown RM, Peng Z, Pati S, Holcomb JB, Park P, Kozar RA. Fresh frozen plasma reduces pulmonary Syndecan-1 shedding and inflammation after hemorrhagic shock. Shock 2011 Vol. 35, (S1), 43.

72.Doursout MF, Pati S, Kozar RA, Xiyun D, Ko TC, Holcomb JB. Assessment of endothelium integrity in hemorrhaged and/or resuscitated rats. Shock 2011 Vol. 35, (S1), 124.

73.Deng X, Cao Y, Doursout M, He G, Kozar RA, Wade CE, Holcomb JB, Ko TC. The role of amp-activated protein kinase (AMPK) in mediating fresh frozen plasma (FFP)’s protective effects in endothelial cells (ECS). Shock 2011 Vol. 35, (S1), 179.

74.Kozar RA, Dyer C, Bulger E, Mourtzakis M, Wade CE, Heyland DK. Elderly trauma patients: Highest risk, fewest calories. JPEN 2011, Vol. 35, S26.

75.Peng Z, Ban K, Kozar RA. Prevention of Hypoxia/Reoxygenation induced IEC-6 cell injury by Glutamine via Syndecan-1. JPEN 2011, Vol. 35, S35-3.

76.Ban K, Peng Z, Kozar RA. Arginine decreases peroxisome proliferator-activatd receptor gamma activity via c-Jun in both ligand-dependent and independent fashions. JPEN 2011, Vol. 35, S35-2.

77.Ban K, Sen A, Peng Z, Kozar RA. Syndecan-1 Mediates Gut Protection by Enteral Glutamine in a Rodent Model of Gut Ischemia/Reperfusion. Shock 2012 37(S): 21.

78.Peng Z, Ban K, Kozar RA. Crosstalk between intracellular PPAR gamma and cell surface syndecan-1 in a rodent model of gut ischemia/reperfusion: a novel observation. Shock 2012 37, supplement:32.

79.Peng Z, Ban K, Kozar RA. Glutamine mitigates lung injury induced by gut ischemia/ reperfusion via intestinal PPAR-gamma. Shock 2013 39(Suppl 2),30.

80.Ban K, Peng Z, Kozar RA. Detrimental effects of ERK ½ inhibition on the intestine during ischemia/reperfusion. Shock 2013 39(Suppl 2),30.

81.Lee JC, Kozar RA, Miller CC, Moore LJ. Optimizing Enteral Nutrition Delivery in a Level ITrauma Intensive Care Unit by Using a Physician-Driven Catch-Up Feeding Protocol. JPEN 2015 39(2): 243-244

82.Kozar R, Peng Z, LeBlanc A, Ban K. Oral Tranexamic Acid: A gut protease inhibitor that mitigates local and distant organ injury after hemorrhagic shock. Shock 2015 43(1): S108-109.

83.Kozar R, Peng Z, LeBlanc A, Ban K. Oral Tranexamic Acid: A gut protease inhibitor that mitigates local and distant organ injury after hemorrhagic shock. Shock 2015 43(1): S108-109.

84.Wu F, Kozar R. Plasma activates a novel Syndecan1-Pak1 pathway to enhance endothelial barrier integrity. Shock 2016 45(1):S1 87.

85.Kozar R, Wu F. MiR inhibits Syndecan-1 expression an enhances endothelial barrier

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dysfunction. Shock 2016. 45(1):S1 87.86. Wu F, Pati S, Kozar R. Fibrinogen contributes to stabilization of cell surface Syndecan-

1: A novel mechanism for endothelial protection by plasma. Shock 2016 45(1):S1 116.87. Wischmeyer P, Kozar R, Dhaliwal R, Jiang X, Day A, Heyland D. The TOP-UP Trial: a

randomized trial of supplemental parenteral nutrition in under and overweight ICU patients. Shock 2016. 45(1):S171.

88.Yang S, Li R, Kozar R, Mackensie C, miller C, Parimi N, Stansbury L, Stein D, Scalea T, Hu P. New prehospital vital signs triage threshold for better prediction of emergency blood transfusion in geriatric in geriatric trauma patients. Shock 2016. 45(1):S1 86.

89.Parimi N, Yang S, Hu P, Li H, Mackenzie C, Kozar R, Fontain MJ, Miller C, Scalea T, Stein D. Emergency blood transfusion following trauma- selecting the right patient. Shock 2016. 45(1):S1 90.

Presentations: (Invitation)

International

1. Invited speaker. Endotheliopathy of Trauma. Trauma Hemostasis and Oxygenation Research Network. Bergen, Norway, June 2014.

National

1. Invited speaker. Staying in academics: Learning how to SWIM (surgeon, women, investigator, and mom). 37th annual meeting of the Association of Academic Surgery, Sacramento, CA. November 2003.

2. Invited speaker. Education Research. Fundamentals of Surgical Research Course. 37 th annual meeting of the Association of Academic Surgery, Sacramento, CA, November 2003.

3. Moderator for the Education session at the 37th annual meeting of the Association of Academic Surgery, Sacramento, CA, November 2003.

4. Invited speaker. Nutrition. AACP Critical Care Board Review Course, Phoenix, AZ, August 2003.

5. Invited speaker. Abdominal Infections. AACP Critical Care Board Review Course, Phoenix, AZ, August 2003.

6. Invited speaker. Early goal-directed monitoring of the trauma patient. Postgraduate course: Resuscitation and the immediate care of the trauma patient. American College of Surgeons, April 2003.

7. Invited speaker. Moderator for the Critical Care session at the 64th annual meeting of the Society of University Surgeons, Houston, TX February 2003.

8. Invited speaker. Sodium coupled solutes modulate small bowel function after ischemia/reperfusion injury. 64th annual meeting of the Society of University Surgeons, Houston, TX February 2003.

9. Moderator for Critical Care Oral Poster Session at the 38 th annual meeting of the

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Association of Academic Surgery, Houston, TX, November 2004.10. Invited speaker. Nutrition in the ICU. AACP Critical Care Board Review Course,

Orlando, FL, August 2004.11. Invited speaker. Abdominal Infections. AACP Critical Care Board Review Course,

Orlando, FL, August 2004.12. Invited speaker. Role of the Gut in Multiple Organ Failure. 33rd Critical Care Congress

of the Society of Critical Care Medicine. February 200413. Moderator for Critical Care Session at the 65th Annual Meeting of the Society of

University Surgeons, St. Louis, MO., February 2004.14. Invited speaker. Philadelphia Annual Day of Trauma, December 19 th, 2005.15. Invited speaker. Implications of Pregnancy on a Surgical Career. Career Development

Course sponsored by the Association of Academic Surgeons and held in conjunction with the 91st Annual Clinical Congress of the American College of Surgeons. October 2005.

16. Invited speaker. Education Research. Fundamentals of Surgical Research Course sponsored by the Association of Academic Surgeons and held in conjunction with the 91st Annual Clinical Congress of the American College of Surgeons. October 2005.

17. Invited speaker. Enteral Support in Critically Ill Surgical Patients: Problems, Placement, and Pitfalls. 33rdrdAnnual Meeting of the American College of Surgeons. April 2005.

18. Moderator for general session of the South Texas Chapter of the American College of Surgeons, Houston, TX March 2005.

19. Moderator for the Education Session at the 66th Annual Meeting of the Society of University Surgeons, Nashville, TN, February 2005.

20. Visiting Professor. US Army Institute of Surgical Research, Fort Sam Houston, TX July 2006.

21. Invited speaker. Nutritional Support in Critically Ill Trauma Patients. Translating Evidence-Based Nutrition into Effective Clinical Care. ASPEN’s Clinical Nutrition Week, February 2006.

22. Moderator for Critical Care session and Education session at the first annual Academic Surgical Congress meeting, San Diego, CA February 2006.

23. Invited Speaker, Society of Leukocyte Biology. Glutamine, a novel PPAR gamma agonist, abrogates gut injury and inflammation in the postischemic gut. Boston, MA. October 2007.

24. Invited Speaker, American College of Surgeons, Review Course in General Surgery. Critical Care. New Orleans, October 2007.

25. Visiting Professor and Speaker, 8th Annual Trauma Symposium, Controversies in Fluid Resuscitation, Medical College of Virginia, April 2007.

26. Invited Speaker, Western Trauma Association, Current Challenges in ICU staffing. February 2007.

27. Visiting Professor, Updates and Upheavals in Nutrition Practice in The Critically Ill. University of California- Davis, Sacramento, CA. May 2008.

28. Invited Speaker, Southwestern Surgical Congress. Glutamine as an isolated immunonutrient. Acapulco, Mexico. March 2008.

29. Invited Speaker, Clinical Nutrition Week. Nutrition in the trauma patient. Chicago, IL. January 2008.

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30. Update on Resuscitation Strategies. The Hobert Trauma Symposium, Methodist Health System, Dallas, TX, October 2008.

31. Visiting Professor, Wright State University, Boonshoft School of Medicine. Endowed Lectureship in Trauma Surgery at Miami Valley Hospital, November 11-12, 2009

32. Invited Speaker, Western Trauma critical decisions in trauma: Liver Injury. Mt. Crested Butte, Co. February 2009.

33. Invited Speaker, Academic Surgical Congress. Career advice I wish I’d been given. Fort Meyers, Fl. February 2009.

34. Invited Speaker, Clinical Nutrition Week. Update on antioxidants, glutamine, and the ideal diet in SICU Patients (M25). New Orleans. February 2009.

35. Invited speaker. General Surgery Update: Sea Pines Resort, Hilton Head Island, South Carolina. June 7-10, 2010.

36. Session chair and speaker for critical care topics. American College of Surgeons General Surgery Review Course 2007-2013.

37. Session chair and speaker for trauma.American College of Surgeons free standing General Surgery Review Course 2010 - 2013.

38. Invited speaker. Update in Critical Care Nutrition: Are We Really Changing the Outcome? American Society for Parenteral and Enteral Nutrition. Las Vegas, NV February 8, 2010.

39. Invited speaker. Austin Trauma and Critical Care Conference. Tranexamic acid and Hepatic Trauma. Austin, TX, June 2011.

40. Invited speaker. American Association of Immunologists. Sensing intestinal nutritive signals within the injured gut. San Francisco, CA, May 2011.

41. Session chair, organizer, and speaker ASPEN: Clinical Nutrition Week.. Pharmaconutrients. Vancouver, CA January 2011.

42. Invited speaker. Shock Society. Glutamine: Changing Outcomes in the ICU, but why? Miami, FL June 2012.

43. Invited speaker. American Association for the Surgery of Trauma. Challenging Cases. Koloa, HI, September 2012

44. Visiting Professor. Department of Surgery. The University of British Columbia, Vancouver, Canada. May 2012

45. Visiting Professor. New York University Department of Surgery, December 201146. Invited speaker. ASPEN: Clinical Nutrition Week. Update in critical care nutrition – What

is state of the art? Optimal route and timing of nutrient delivery. Orlando, FL, January 2012.

47. Invited speaker. Trauma Quality Improvement Program. Role of TEG based resuscitation. Phoenix, AR, November 2013.

48. Invited speaker. American Association for the Surgery of Trauma. Hemostatic resuscitation for traumatic hemorrhage: What is the role of TXA, PCC, and fibrinogen in treating acute traumatic coagulopathy. San Francisco, CA, September 2013.

49. Visiting Professor. Department of Surgery. Hofstra North Shore-LIJ School of Medicine. April 2013.

50. Visiting Professor, Department of Surgery, Texas Tech Health Science Center, speaker at the 20th annual Trauma and Critical Care Symposium, November 2014.

51. Invited speaker. Trauma Quality Improvement Program. Changes in Trauma

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Verification. Chicago, IL November 2014. 52. Invited speaker. 22nd Annual Trauma Symposium sponsored by Memorial Healthcare

System. Hollywood, FL February 2015.53. Visiting Professor, Department of Surgery. University of Colorado, Denver Co. May

2015.54. Visiting Scientist, NAMRU, San Antonio, TX, September 201555. Invited speaker, 74th Annual Meeting of the American Association for the Surgery of

Trauma, How to develop and manage a research career and obtain funding, Las Vegas, NV September 2015.

56. Invited speaker, 63rd Annual Detroit Trauma Symposium. Detroit, MI November 2015. 57. Founders Basic Science Lecturer. Western Trauma Association. Squaw Creek, CA

February 2016.58. Invited Speaker. Trauma, Critical Care, and Acute Care Surgery Conference. Las

Vegas, NV March 2016.59. Invited Speaker. Medical Disaster Response Conference. Las Vegas, NV March 2016.60. Invited Speaker. 18th Annual AtlantiCare Trauma Symposium. Atlantic City, NJ May

2016.61. Visiting Professor for the Milton A. Lunda Memorial Lecture. Gunderson Health System,

LaCrosse, Wisconsin. May 201662. Visiting Professor, Medical College of Wisconsin, Milwaukee, Wisconsin May 2016.63. Visiting Professor, East Carolina University, Greenville, NC, May 201664. Key Note Faculty, Harborview Medical Center EMS & Trauma Conference. September

2016.65. Key Note Speaker, Southwest Trauma and Acute Care Symposium; November 2016.

Regional

1. Invited speaker. Nutrition in the Surgical ICU. Texas Society for Parenteral and Enteral Nutrition, Dallas, TX, September, 2003.

2. Invited speaker. Enteral Feeding Protocol, Society for Parenteral and Enteral Nutrition, Houston, Texas, April 2004.

3. Invited speaker. Glutamine, a novel PPAR gamma mediator. Digestive Disease Center, Houston, TX, 2007

4. Invited speaker and moderator. Committee on Women’s Issues, American College of Surgeons. Women in Surgery: Career Development Seminar. Houston, Texas November 19 – 20, 2009

5. Invited speaker. Austin Trauma & Critical Care Conference. Austin, TX, June 2 – 3, 2011.

Local

1. Pancreaticoduodenal Trauma. Surgical Grand Rounds, Allegheny University of the Health Sciences, Philadelphia, PA, October 1996.

2. Abdominal Trauma. Surgical Grand Rounds, Crozier Chester Medical Center, Philadelphia, PA, October 1997.

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3. Pancreatic and Duodenal Trauma. Surgical Grand Rounds, Mercy Catholic Medical Center, Philadelphia, PA, September 1997.

4. Penetrating Trauma. Division of Emergency Medicine, St. Christopher’s Hospital for Children, Philadelphia, PA, February 1998.

5. Gut Absorptive Capacity Following Shock-Induced Gut Ischemia. Red Duke Professorship Day, University of Texas-Houston, Houston, TX, January 2000.

6. Trauma Critical Care Overview. Department of Emergency Medicine,University of Texas-Houston School of Medicine, Houston, TX, May 2001.

7. Effect of Intraluminal Nutrients on Gut Ischemia/Reperfusion. Red Duke Professorship Day, University of Texas-Houston, TX, January 2001.

8. Intraluminal Nutrients Modulate Gut Ischemia/Reperfusion Injury. Red Duke Professorship Day, University of Texas-Houston, Houston, TX, January 2002.

9. Education Research. Grand Rounds. Department of Surgery, University of Texas-Houston, Houston, TX November 2003.

10. ICU considerations of the morbidly obese. Grand Rounds, Department of Surgery, University of Texas-Houston, Houston, TX, January, 2003.

11. Enteral Nutrition. From Bedside to Benchwork. Grand Rounds. Department of Surgery, University of Texas-Houston, Houston, TX, February 2006.

12. Update on Enteral Nutrition. Grand Rounds, Pulmonary and Critical Care, Department of Medicine, University of Texas-Houston, Houston, TX April 2007.

13. Challenges in ICU Staffing. Grand Rounds. Department of Surgery. University of Texas-Houston, Houston, TX 2008

14. Potential therapeutics to mitigate trauma-hemorrhagic shock induced gut and lung dysfunction. Center for Vascular and Inflammatory Diseases, University of Maryland, Baltimore. December 2014.

15. Plasma based resuscitation. Grand Rounds. Department of Surgery. University of Maryland Baltimore. December 2015.

16. Update on nutrition for the critically ill. Grand Rounds. Department of Surgery. University of Maryland. December 2016.

National Research Presentations

1. Kozar RA, Pownall HJ. Cellular phospholipid efflux. Presented at the Aspen Bile Salt Meeting, Aspen, CO, August 1991.

2. Kozar RA, McKeone BJ, Pownall HJ. Free radical-induced alterations in endothelial cell function. Presented at the Resident’s Section of Society of University Surgeons, Cincinnati, OH, February 1992.

3. Kozar RA, McKeone BJ, Pownall HJ. Mechanism of cellular phospholipid efflux. Presented at the Association for Academic Surgery, Montreal, Quebec, Canada, November 1992.

4. Kozar RA, White JV, Pownall HJ. Reverse cholesterol transport: The mechanism of phospholipid exchange between cell membranes and high density lipoprotein. Presented at the Delaware Valley Vascular Society, Philadelphia, PA, September 1994.

5. Kozar RA, Harada R, Jaffe F, Cindrick L, White JV. Carbon dioxide angioscopy: Hemodynamic and hemorrheologic responses to large volume CO2 insufflation of the

Kozar RA

arterial tree. Presented at the Eastern Vascular Society, Montreal, Quebec, Canada, May 1994.

6. Trooskin SZ, Kozar RA, Blank-Reid CA, Santora TA, Talucci, RC, DeSantis D, Townsend RN. Gender issues in trauma admission: The neglected elderly female. Oral Presentation. Philadelphia Academy of Surgery, Philadelphia, PA, September 1996.

7. Fuchs B, Kozar RA, Smull G, Chang B, McMaster J, Getsy J, Talucci RC: Role of Under-Appreciation of Sleep Disorders as a Cause of Motor Vehicle Crashes. Presented at the Pennsylvania Division for the American Trauma Society's Annual Conference, Hershey, PA. April 1997.

8. Kaplan LJ, Kozar RA, Bailey H, Blank-Reid C, Santora TA, Talucci RC, Trooskin SZ. The challenge of pregnant trauma patients: Insight gained from review of a state trauma registry. Presented at the American Association for the Surgery of Trauma. Sept 1998.

9. Kozar RA, Abedin ZR, Abedin MZ, Trooskin SZ. Expression of epidermal growth factor in Type II Pneumocytes: A potential mechanism for recovery from acute lung injury. Presented at Biomedicine '98. May 1-3, 1998.

10.Hassoun HT, Weisbrodt NW, Kozar RA, Mercer DW, Moody FG, Moore FA. Inducible nitric oxide synthase mediates impaired small intestinal transit after severe gut ischemia/reperfusion. Presented at the 34th Annual Meeting of the Association for Academic Surgery, November 2-4, 2000, Tampa, Florida.

11.Kozar RA, Kaplan LJ, Cipolla J, Meija J, Haber M. Laparoscopic repair of traumatic diaphragmatic injuries. Presented at the 34th Annual Meeting of the Association for Academic Surgery, November 2-4, 2000, Tampa, Florida.

12.Kozar RA, Schultz SG, Weisbrodt N, DeSoignie R, Hassoun HT, Moore FA. Intraluminal nutrients enhance gut ischemia/reperfusion injury. Presented at the Shock Society, June 2000, Snowbird, Utah.

13.Cipolla J, Kozar RA, Satz WA, Kaplan LJ. Mass transit strike hits cyclists. Presented at the meeting of the Society of Academic Emergency Medicine, May 2000, San Francisco, CA.

14.Hassoun HT, Weisbrodt N, Moody FA, Kozar R, Grossie VB, Moore FA. Nitric Oxide synthetase II is upregulated in ileus after intraperitoneal lipopolysaccharide but not gut ischemia/reperfusion. Presented at the Society of University Surgeons, February 2000, Toronto, Canada.

15.McKinley BA, Kozar RA, Cocanour CS, Marquez A, Sailors RM, Ware DN, Moore FA. Trauma resuscitation: female hearts respond better. Presented at the annual meeting of the Western Surgical Association, November 2001.

16.Kozar RA, Moore EE, Kudsk K, Jurkovich G, Moore FA. Enteral tolerance following severe trauma is reliably achieved by a standardized protocol. Presented atThe 35th Annual Meeting of the Association of Academic Surgery. November 2001.

17.Hassoun HT, Kone BC, Kozar RA, Lai M, Moore FA. -Melanocyte stimulating hormone augments gut ischemia-reperfusion induced heme oxygenase expression. Presented at the American College of Surgeons, October 2001.

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18.Garner GB, Ware DN, Cocanour CS, Duke JH, McKinley BA, Kozar RA, Moore FA. Vacuum assisted wound closure provides early fascial reapproximation in trauma patients with open abdomens. Presented at the Southwestern Surgical Congress, Cancun, Mexico, April 2001.

19.Kozar RA, Schultz SG, Hassoun HT, DeSoignie R, Moore FA. Intraluminal nutrients alter gut permeability following gut ischemia/reperfusion. Presented at the 24 th Annual Conference on Shock. February 2001.

20.Von Maszewski M, Cocanour CS, McKinley B, Kozar RA, DeSoignie R, Weisbrodt N,Moore FA. MMC’s exist after trauma and predict enteral tolerance. Presented at the 31st Annual Meeting of the Western Trauma Association, Big Sky, Montana, February 2001.

21.Hassoun HT, Kone BC, Kozar RA, Snuggs M, Phan T, Moore FA. -Melanocyte stimulating hormone reduces intestinal NF-B and gut ischemia/reperfusion injury. Presented at the Society of University Surgeons, February 2001.

22.Mangram A, Kozar RA, Gregoric I, Grant P, Moore FA. Unsuspected fracture penetrations of the heart. Presented at the 31st Annual Meeting of the Western Trauma Association, Big Sky, Montana, February 2001.

23.Hassoun HT, Kozar RA, DeSoignie R, Thorpe L, Kone BC, Miller CC, Safi HJ, Moore FA. Intraischemic topical hypothermia prevents intestinal mucosal injury during mesenteric ischemic/reperfusion. Presented at the Southern Association for Vascular Surgery, Puerto Rico, January 2001.

24.Kozar RA, Hu S, Schultz SG, Hassoun HT, Moore FA. Specific enteral nutrients altermucosal blood flow during gut ischemia/reperfusion. Presentation at the 25 th Clinical Congress of the American Society for Parenteral and Enteral Nutrition , January 2001, Chicago, Illinois.

25.Zsolt, B., M.D., McKinley, B., Ph.D., Cocanour, C., M.D., Kozar, RA, Valdivia, A., R.N., Sailors. M., Ph.D., Moore, F., M.D. Supra-Normal Trauma Resuscitation causes more case of abnormal compartment syndrome. Presented at the Western Surgical Association, November 2002.

26.Brundage SI, Lucci A, Miller CC, Azizzadeh A, Kozar RA. Potential targets to encourage a surgical career. Presented at the Western Surgical Association, November 2002.

27.Kozar RA, Lucci A, Azzizadeh A, Miller CC, Cocanour CS, Potts J, Fischer C, Brundage SI. A brief intervention by surgeons can influence medical students towards a career in surgery. Presented at the plenary session of the 2002 Annual meeting of the Association for Academic Surgery, November 2002.

28.Kozar RA, Holcomb JB, Macatis J, DeSoignie R, Moore FA. Superior mesenteric artery occlusion (SMAO) models shock-induced gut Ischemia/reperfusion. Presented at the 2002 Annual meeting of the Association for Academic Surgery, November 2002.

29.Attuwaybi BO, Hassoun H, Kozar RA, Moore FA. Hypothermia protects against gut ischemia-reperfusion (I/R) induced impaired intestinal transit by inducing impaired intestinal transit by inducing heme oxygenase-1 (HO-1). Presented at the 2002 Annual meeting of the Association for Academic Surgery, November 2002.

30.Tyroch A, McGuire E, McLean S, Kozar R, Gates K, Kaups K, Cook C, Griswold J, Sue

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L, Craun M, Prices J. The prognostic significance of Chance fractures and intra-abdominal injuries revisited: a multi-center review. Presented at the 62nd Annual Meeting of the American Association for the Surgery of Trauma, September 2002.

31.Hassoun HT, Kozar RA, Kone BC, Safi H, Moore FA. Hypothermia differentially modulates oxidative stress proteins during gut ischemia/reperfusion. Presented at the 63rd Annual meeting of the Society of University Surgeons, February 2002.

32.Kozar RA, Attuwaybi B, Sato N, Moore-Olufemia S, Weisbrodt NW, Moore FA. Hypertonic saline prevents inflammation and impaired intestinal transit after gut ischemia/reperfusion by inducing heme oxgenase 1(H0-1) enzyme. Presented at the American Association for the Surgery of Trauma, September 2003.

33.Sato N, Kozar RA, Smith M, Zou L, Moore-Olufemi S, Schultz SG, Moore FA. Immune enhancing enteral agents differentially modulate the early pro-inflammatory transcription factors mediating gut ischemia/reperfusion. Presented at the American Association for the Surgery of Trauma. Maui, Hawaii, October 2004.

34.Kozar RA, Sati N, Lei Z, Smith M, Moore FA. Immune enhancing agents differentially modulate gut injury and inflammation. Presented at the 65 th meeting of the Society of The University Surgeons, February 2004.

35.Sato N, Kozar RA, Lei Z, Weatherall J, Attuwaybi B, Moore-Olufemia S, Moore FA.Induction of peroxisome proliferators activated receptor (PPAR) gamma, the Cox-2 inhibitor, NS 398, reverses mesenteric ischemia/reperfusion gut inflammation. Presented at the 65th meeting of The Society of University Surgeons, February 2004.

36.Kozar RA, Schultz SG, Verner-Cole E, Bick R, DeSoignie R, Poindexter B, Moore FA. Enternal arginine, an immune enhancing agent, impair gut barrier function following mesenteric ischemia/reperfusion. 34th Annual Meeting of Western Trauma Association, February 2004.

37.Kozar RA, Moore JB, Miles SE, Holcomb JH, Moore EE, Cothern C, Moore FA. Complications of nonoperative management of high grade blunt hepatic injuries. Presented at the 35th Annual Meeting of the Western Trauma Association, Jackson Hole, WY, March 2005.

38.Gonzalez EA, Hunter R, Kozar RA, Weisbrodt N, Field E, Moore FA. Poloxamer 188 resuscitation after mesenteric ischemia/reperfusion abrogates neutrophil mediated ileal mucosal injury. Presented at the American Association for the Surgery of Trauma Annual Meeting New Orleans, Louisiana, September 2006.

39.Gonzalez EA, Hunter R, Kozar RA, Moore FA. Poloxamer 188-Hypertonic saline provides optimal ileal protection after mesenteric ischemia/reperfusion. Presented at the 2nd Academic Surgical Congress, Phoenix, AZ, February 2007.

40.Ban K, Gonzalez EA, Kone BC, Kozar RA. Enteral arginine modulates the effect of pharmacologic inhibition of AP-1 on iNOS in the postischemic gut. Presented at the 30th annual meeting of the Shock Society, Baltimore, MD, June 2007.

41.Moore-Olufemi SD, Moore FA, Gonzalez EA, Ban K, Fields E, Kone BC, Kozar RA. Transcriptional profiling of hypertonic saline in rat small intestine. Presented at the 30 th annual meeting of the Shock Society, Baltimore, MD, June 2007.

42.Ban K, Peng, Z, Kozar RA. PPAR mediates the regulation of INOS expression by C-JUN/AP-1. Poster presentation at the Shock Society, Portland, OR, June 2010.

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43.Matijevic N, Wang WY-W, Kozar RA, Gonzales E, Holcomb JB, Low levels of platelet microparticles correlate with poor outcomes in shock patients. Presented at the 33 rd Annual Conference on Shock, Portland, OR, June 2010.

44.Duan C, Cao Y, Deng X, Yang W, Kozar RA, Gonzalez EA, Holcomb JB, Ko TC. Plasma adiponectin levels decrease after hemorrhagic shock (HS). Presented at the 33rd Annual Conference on Shock, Portland, OR, June 2010.

45.Peng Z, Haywood-Watson R, Pati S, Dong J, Vijayan V, Holcomb JB, Ko T, Kozar RA. Restitution of syndecan-1 is modulated by age of fresh frozen plasma (FFP). Presented at the 33rd Annual Conference on Shock, Portland, OR, June 2010.

46.Brown RM, Peng Z, Pati S, Holcomb JB, Park P, Kozar RA. Fresh frozen plasma reduces pulmonary Syndecan-1 shedding and inflammation after hemorrhagic shock. Poster presentation at the Shock Society, 2011.

47.Ban K, Sen A, Peng Z, Kozar RA. Syndecan-1 Mediates Gut Protection by Enteral Glutamine in a Rodent Model of Gut Ischemia/Reperfusion. Oral presentation at the Shock Society, 2012.

48.Peng Z, Ban K, Kozar RA. Crosstalk between intracellular PPAR gamma and cell surface syndecan-1 in a rodent model of gut ischemia/reperfusion: a novel observation. Poster presentation at the Shock Society, 2012.

49.Kozar R, Holcomb JB, Nathens A. American Association for the Surgery of Trauma Are all deaths created equally? The impact of hospice care on risk-adjusted mortality. San Francisco, CA, September 2013.

50.Peng Z, Ban K, Kozar RA. Glutamine mitigates lung injury induced by gut ischemia/reperfusion via intestinal PPAR-gamma. Oral presentation at the Shock Society, 2013.

51.Ban K, Peng Z, Kozar RA. Detrimental effects of ERK ½ inhibition on the intestine during ischemia/reperfusion. Poster presentation at the Shock Society, 2013.

52.Shackford SR, Kahl JE, Calvo RY, Kozar RA, Haugen CE, Kaups KL, Willey M, Tibbs BM, Mutto SM, Rizzo AG, Lormel CS, Shackford MC, Burlew CC, Moore EE, Cogbill TH, Kallies KJ, Haan JM, Ward J. Gunshot wounds and blast injuries to the face are associated with significant morbidity and mortality: Results of an 11-year multi-institutional study of 720 patients. Oral presentation at the Western Trauma Association, 2013.

53.Shalhub S, Starnes BW, Brenner ML, Biffl WL, Azizzadeh A, Inaba K, Skiada D, Zarzaur B, Nawaf C, Eriksson EA, Fakhry SM, Paul JS, Kaups KL, Ciesla DJ, Todd SR, Seamon MJ, Capano-Wehrle LM, Jurkovich GJ, Kozar RA. Blunt abdominal aortic injury: A Western Trauma Association multicenter study. Oral presentation at the Western Trauma Association, 2013.

54.Syndecan-1 mediated gut protection by fresh frozen plasma and lyophilized plasma after hemorrhagic shock. Oral presentation at the Military Health System Research Symposium. Fort Lauderdale, FL, August 2014.

55.Kozar RA, Holcomb JB, Xiong W, Nathens AB. Are all deaths created equally? The impact of hospice care on risk-adjusted mortality. Oral presentation at the Annual Association for the Surgery of Trauma, 2014.

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