Robertson Parkman, M.D.CURRICULUM VITAE

A. PERSONAL INFORMATION

Name in Full: Robertson Parkman, MDBusiness Address: PO Box 1537

Pebble Beach, CA 93953Business Phone: (626) 840-1062Business Fax: (831) 626-2668Home Address: P.O. Box 1537

Pebble Beach, CA 93953Home Phone: (831) 626-1010Place of Birth: Pittsburgh, PennsylvaniaCitizenship: U.S.A.E-Mail Address: rparkman@usc.edu

B. EDUCATION

High School: l956 The Hill SchoolPottstown, Penn.

College: l960 AB Organic Chemistry Cum Laude Amherst College Amherst, Mass.

Medical School: l965 MD Yale UniversitySchool of MedicineNew Haven, Conn.

Internship: 1965-66 (Pediatrics)Yale-New Haven HospitalNew Haven, Conn.

Residencies: 1966-67 (Pediatrics)Yale-New Haven HospitalNew Haven, Conn.

1969-70 (Pediatrics)Childrens Hospital Medical CenterBoston, Mass.

Fellowship: 1963-64 USPHS Fellow, Wright-Fleming InstituteSt. Mary's HospitalLondon, England

1967-69 Research AssociateCarcinogenesis Section

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Robertson Parkman, M.D.National Cancer InstituteNational Institutes of HealthBethesda, MD.

Fellowship: 1970-72 Fellow in Medicine(Immunology)Childrens Hospital Medical CenterBoston, Mass.

Honors and Awards: 1971-72 Fellow, Medical Foundation1972-74 Fellow, Leukemia Society of America1974-79 Scholar, Leukemia Society of America2007 Lifetime Achievement Award from the American Society for

Blood and Marrow Transplantation2010 Lifetime Achievement Award from the Pediatric Blood and

Marrow Transplant ConsortiumLicensure: 1983 - California - #G49869

1972 - 83 Massachusetts -#32269 1965 - 67 Connecticut

Board Certification: 1972 American Board of Pediatrics1979 American Board of Allergy and

Immunology1986 Diagnostic Laboratory Immunology

C. PROFESSIONAL BACKGROUND

Academic Appointments: 1969-1971 Teaching Fellow in PediatricsHarvard Medical SchoolBoston, Mass.

1971-1974 Instructor in PediatricsHarvard Medical SchoolBoston, Mass.

1974-1978 Assistant Professor of PediatricsHarvard Medical SchoolBoston, Mass.

1978-1982 Associate Professor of PediatricsHarvard Medical SchoolBoston, Mass.

1983-2014 Professor of Pediatrics, Immunology, and MicrobiologyKeck School of Medicine, University of SouthernCalifornia Los Angeles, Calif.

2014-pres Emeritus, Professor of Pediatrics, Immunology, and Microbiology Keck School of Medicine, University of Southern

California Los Angeles, Calif.

2015-pres Consulting Professor of Pediatrics, Stanford University, Palo Alto, CA

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Robertson Parkman, M.D.

Hospital Appointments: 1972-1976 Assistant in Medicine (Immunology)Childrens Hospital Medical CenterBoston, Mass.

1974-1978 Assistant in Hematology and OncologyChildrens Hospital Medical CenterBoston, Mass.

1974-1982 Senior PhysicianSidney Farber Cancer InstituteBoston, Mass.

1975-1979 Associate in Medicine Childrens Hospital Medical CenterBoston, Mass.

1976-1979 Associate in ImmunologyChildrens Hospital Medical CenterBoston, Mass.

1979-1982 Senior Associate in Medicine and ImmunologyChildrens Hospital Medical CenterBoston, Mass.

1983-2002 Head, Division of Research Immunology/ Bone Marrow TransplantationChildrens Hospital Los AngelesLos Angeles, Calif.

1989-1999 Director, Human Lymphocyte Antigen (HLA) LaboratoryChildrens Hospital Los Angeles

1993-2002 Associate Director for Clinical ResearchChildrens Hospital Research InstituteChildrens Hospital Los AngelesLos Angeles, Calif.

1999-2000 Interim DirectorChildrens Hospital Research InstituteChildrens Hospital Los AngelesLos Angeles, Calif.

2002-2012 Co-director, HLA LabChildrens Hospital Los Angeles

2015-pres Member, Division of Stem Cell Transplantation/ Regenerative Medicine, Lucille Packard Children’s Hospital, Palo Alto, CA

Visiting Appointments: 1981 McLaughlin Visiting ProfessorMedical BranchUnion of TexasGalveston, Texas

2013 Hazen Cherry Lecturer, Mattel Children’s Hospital,

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Robertson Parkman, M.D. Geffen School of Medicine, UCLA, Los Angeles, CA

Military Service: 1967-1979 SurgeonU.S. Public Health Service

D. SO CIETY MEMBERSHIPS

American Association of ImmunologistsInternational Society for Experimental HematologySociety for Pediatric ResearchAmerican Pediatric SocietyAmerican Society of HematologyAssociation of American PhysiciansAmerican Society for Blood and Marrow Transplantation

Founding Treasurer

E. HOSPITAL COMMITTEES

1983-2008 Research Committee,Childrens Hospital Los Angeles

1985-2002 Intern Selection CommitteeChildrens Hospital Los Angeles

1985-1986 Program Priority CommitteeChildrens Hospital Los AngelesChairman

Hospital Committees: 1986-1999 Committee on Clinical Investigation (IRB)Children’s Hospital Los Angeles

1986-1989 Chairman1990-1991 Program Evaluation Committee

Children’s Hospital Los AngelesChairman

1993-1994 Department of Pediatrics Cabinet CommitteeChildren’s Hospital Los Angeles

1993-2008. Research Advisory CommitteeChildren’s Hospital Los Angeles

1994-2002 University Children’s Medical Group Board (Private Practice Plan)

F. EXTRAMURAL COMMITTEES

National Institutes of 1983,1984 Immunological Sciences StudyHealth Section

1987-1991 Gene Therapy Subcommittee ofRecombinant DNA Advisory Committee

1991-1996 Recombinant DNA Advisory Committee

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Robertson Parkman, M.D.1993-1995 Hematology 2 Study Section

American Cancer Society 1987-1991 Immunology Study Section1990-1991 Chairman

American Cancer Society 1996-2002 FAHCT Council CommitteeAmerican Society of 1987-1990 Pediatric Hematology Subcommittee Hematology ChairmanUniversity of Southern 1985-1987 Faculty Innovation and ResearchCalifornia School of Medicine Fund

1989-1991 Scientific Council Telethon (Italy) 1999-2002 Member, Scientific Review Committee, 2002-2004 Chairman, Scientific Review Committee 2004-2014 Member, Scientific Advisory Committee

National Heart, Lung and 1999-2003 Board of External Advisors Blood Institute 2001-Pres Chairman, Data and Safety Monitoring

Board for Gene Transfer and Cellular Therapy 2011-2014 PACT, Scientific Advisory Board 2011-2014 Special Emphasis Review (KO8) Committee Section 2014-pres Mentored Clinical and Basic Science Review Committee National Institute of Diabetes 2002-2009 Scientific Advisory Board, And Digestive and Kidney Stem Cell Genomics Program Disease

Department of Health and 2007-2011 Member, Advisory Committee on Blood Stem Cell Human Services Transplantation (ACBSCT)

Cancer Research Prevention 2014-Pres Member, Scientific Review Committee in Texas

RESEARCH GRANTS

COMPLETED GRANTS1) SCOR in HSC Biology 9/1/1995 – 8/31/2008

NIH HL 54850Project 4 – HSC TransplantationRole: Principal Investigator

Clinical trials of gene therapy for ADA deficiency and X-linked SCID and the transplantation of FACS isolated HSC.

2) SCOR in HSC Biology 9/1/1995 – 8/31/2008NIH HL 54850Administrative CoreRole: Principal Investigator

Administrative oversight of SCOR grant.

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Robertson Parkman, M.D.

3) Rebuilding Immunity for Survival 12/01/03– 11/30/09 NIH/NCI PO1 CA100265-01A1Program Project GrantImmune Assessment Core (Core C)Role: Project Leader (PI: Lee Nadler)

The major goal of this project is to provide immune evaluations of transplant recipients on multi-center or group-wide clinical trials.

PUBLICATIONS

PEER REVIEW1. Glynn AA and Parkman R. Studies with an antibody to rat lysozyme. Immunology 7:724-729,1964.2. Parkman R, Levy JA, Ting RC. Murine sarcoma virus: the question of defectiveness. Science

168:387-389, 1970. 3. Fischer DS, Parkman R, Finch SC. Acute iron poisoning: a survey of the problem with suggestion

regarding therapy. J Am Med Assoc 218:1179-1183, 1971.4. Parkman R. The relationship of gender to hemolytic disease of the newborn. J Pediatr 80:469-471,

1972.5. Colten HR and Parkman R. Biosynthesis of C4 (fourth component of complement) by hybrids of

C4-deficient guinea pig cells and HeLa cells. Science 176:1029-1031, 1972.6. Parkman R, Hagemeier A, Merler E. Selective hybrid cell formation by human lymphoid cells. J Cell

Physiol 81:55-62, 1973.7. Parkman R and Merler E. Discontinuous density gradient and analysis of the developing human thymus.

Cell Immunol 8:328-331, 1973.8. Parkman R and Merler E. Thymus-dependent functions mouse thymocyte-fibroblast hybrid cells. Nature

(New Biol.) 245:114-116, 1973.9. Parkman R, Mosier D, Umansky I, Cochran W, Carpenter CB and Rosen FS: Graft-versus-host disease

following intrauterine and exchange transfusions. N Engl J Med 290:359-363, 1974.10. Camitta BM, Nathan DG, Forman EN, Parkman R, Rappeport JM and Orellana TD. Post-hepatic aplastic

anemia: an indication for early bone marrow transplantation. Blood 43:473-483, 1974.11. Parkman R. Hybrid tumor cells: an immunotherapeutic agent. J Natl Cancer Inst 52:1541-1545, 1974.12. Geha RS, Gatien JG, Parkman R, Crain JD, Rosen FS, Merler E. Discontinuous density gradient analysis

of human bone marrow: presence of alloantigen-responsive, PHA-unresponsive cells in normal bone marrow: absence of B lymphocytes in the bone marrow of patients with X-linked agammaglobulinemia. Clin Immunol Immunopathol 2:404-415, 1974.

13. Jacobson MS, Parkman R, Button LN, Jaeger RJ, Kevy SV. Toxicity of human serum stored in flexible polyvinylchloride containers on human fibroblast cell cultures: An effect of di-2-ethylhexyle phthalate. Res Commun Chem Pathol Pharmacol 9:315-323, 1974.

14. Camitta BM, Rappeport JD, Parkman R, Nathan DG. Selection of patients for bone marrow transplantation in severe aplastic anemia. Blood 45:355-363, 1975.

15. Parkman R, Gelfand EW, Rosen FS, Sanderson A and Hirschhorn R. Severe combined immunodeficiency and adenosine deaminase deficiency. N Engl J Med 292:714-719, 1975.

16. McCaffrey R, Harrison TA, Parkman R, Baltimore D. Terminal transferase activity in leukemic cells and normal thymocytes. N Engl J Med 292:775-779, 1975.

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Robertson Parkman, M.D.17. Gatien JG, Schneeberger EE, Parkman R, Merler E. Isolation on discontinuous gradients of bovine

serum albumin a subpopulation of human lymphocytes exhibiting precursor characteristics. Eur J Immunol 5:306-312, 1975.

18. Hirschhorn R, Berates N, Rosen FS, Parkman R, Polmar SH. Adenosine deaminase deficiency in a child diagnosed prenatally. Lancet 1:73-87, 1975.

19. Parkman R, Rosen FS, Rappeport J, Camitta B, Levey RL, Nathan DG. Detection of histocompatibility antigen differences between HLA identical and MLC non-reactive siblings. Transplantation 21:110-116, 1976.

20. Agarwal RP Crabtree GW, Parks RE Jr, Nelson JA, Keightley R, Parkman R, Rosen FS, Stern RC, Polmar SH. Purine nucleoside metabolism in the erythrocytes of patients with adenosine deaminase deficiency and severe combined immunodeficiency. J Clin Invest 57:1025-1035, 1976.

21. Parkman R and Rosen F. Identification of a subpopulation of lymphocytes in human peripheral blood cytotoxic to autologous fibroblasts. J Exp Med 144:1520-1530, 1976.

22. Yu A, Watts H, Jaffe N, Parkman R. Concomitant presence of tumor specific cytotoxic and inhibitor lymphocytes in patients with osteogenic sarcoma. N Engl J Med 297:121-127, 1977.

23. Camitta BM, Quesenberry PS, Parkman R, Boxer LA, Stossel TP, Cassady JR, Rappeport JM, Nathan DG. Bone marrow transplantation for an infant with neutrophil dysfunction. Exp Hematol 5:109-116, 1977.

24. Levey RH and Parkman R. Whole anti-lymphocyte serum: A potent safe immunosuppressive agent for intravenous use in man. Transplant Proc 9:1019-1022, 1977.

25. Greenberger JS, Campos-Neto A, Parkman R, Moloney WC, Karpas A, Schlossman SF, Rosenthal DS. Immunologic detection of intracellular and cell-surface lysozyme with human and experimental leukemic leukocytes. Clin Immunol Immunopathol 8:318-334, 1977.

26. Pratt DM, Strominger J, Parkman R, Kaplan D, Schwaber J, Rosenberg N, Scher CD. Abelson virus-transformed lymphocytes: Null cells that modulate H-2. Cell 12:683-690, 1977.

27. Littman BH, Rocklin RE, Parkman R and David JR. Transfer factor treatment of chronic mucocutaneous candidiasis: Requirement for donor reactivity to candida antigen. Clin Immunol Immunopathol 9:97-110, 1978.

28. Parkman R, Rappeport J, Camitta B, Levey R, Rosen FS. Prognostic value of antibody techniques to detect presensitization in patients with aplastic anemia. Transplant Proc X:71-73, 1978.

29. Levin MJ, Parkman R, Oxman MN, Rappeport JM, Simpson M, Leary PL. Proliferative and interferon responses by peripheral blood mononuclear cells after bone marrow transplantation in man. Infect Immun 20:678-684, 1978.

30. Parkman R, Rappeport J, Geha R, Belli J, Cassady R, Levey R, Nathan DG, Rosen FS. Complete correction of the Wiskott-Aldrich syndrome by allogeneic bone marrow transplantation. N Engl J Med 298:921-927, 1978.

31. Parkman R, Rappeport J, Camitta B, Levey R, Nathan D. Successful use of multi-agent immunosuppression in the bone marrow transplantation of sensitized patients. Blood 52:1163-1169, 1978.

32. Osband M, Parkman R. The control of autoreactivity. I. Lack of autoreactivity in murine spleens is due to concomitant presence of suppressor and autocytotoxic lymphocytes. J Immunol 121:179-185, 1978.

33. Levey R, Parkman R, Rappeport J, Nathan D, Rosen F. Successful bone marrow transplantation in sensitized recipients. Transplant Proc XI:199-204, 1979.

34. Reinherz E, Parkman R, Rappeport J, Rosen F, Schlossman S. Aberrations of suppressor T cells in human graft-versus-host disease. N Engl J Med 300:1061-1068, 1979.

35. Rappeport J, Mihm M, Reinherz E, Lopansri S, Parkman R. Acute graft-versus-host disease in

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Robertson Parkman, M.D.recipients of bone marrow transplants from identical twin donors. Lancet 2:717-720, 1979.

36. Parkman R, Rappeport J, Rosen F. Human graft-versus-host disease. J Invest Dermatol 74:276-279, 1980.

37. Rappeport J, Parkman R, Newburger P, Camitta B, Chusid M. Correction of infantile agranulocytosis (Kostman's Syndrome) by allogeneic bone marrow transplantation. Amer. J. Med. 68:605-609, 1980.

38. Harmon WE, Grupe WE, Parkman R. Control of autologous immune complex nephritis. I. Suppression of the disease in the presence of T-cell sensitization. J Immunol 124:1034-1038, 1980.

39. Bernhard WF, Colo NA, Wesolowski JS, Szycher M, Fishbein MC, Parkman R, Franzblau CC and Haudenschild CC. Development of collagenous linings on impermeable prosthetic surfaces. J Thoracic Cardiovascular Surg 79:552-564, 1980.

40. Camitta BM, Rappeport JM, Parkman R, Nathan DG. Bone marrow transplantation for severe aplastic anemia in children. Am J Pediatr/Oncol 2:145-153, 1980.

41. Jacobson MS, Kevy SV, Parkman R and Wesolowski JS. An in vitro evaluation of a new plasticizer for polyvinyl chloride medical devices. Transfusion 20:443-447, 1980.

42. Bernhard WF, Colo NA, Szycher M, Wesolowski JS, Haudenschild CC, Franzblau CC, Parkman R, Liss RH. Development of a nonthrombogenic collagenous blood-prosthetic interface. Ann Surg 192:369-381, 1980.

43. Sullivan R, Quesenberry PJ, Parkman R, Zuckerman KS, Levey RH, Rappeport JM, Ryan M. Aplastic anemia. Lack of inhibitory effect of bone marrow lymphocytes on in vitro granulopoiesis. Blood 56:625-632, 1980.

44. Geha R, Twarog F, Rappeport JM, Parkman R, Rosen F. Increased serum IgE levels following allogeneic BMT. J Allergy Clin Immunol 66:78-81, 1980.

45. Osband M, Lipton J, Lavin P, Levey R, Vawter G, Greenberger J, McCaffrey R, Parkman R. Histiocytosis-X: Demonstration of abnormal immunity, T-cell histamine H2 receptor deficiency and successful treatment with thymic extract. N Engl J Med 304:146-153, 1981.

46. Parkman R. Cellular basis of autoimmune hemolytic anemia. Am J Pediatr Hematol/Oncol 3:105-110, 1981.

47. Parkman R, Rappeport JM, Belli JA, Cassady JR, Levey R. Correction of congenital bone marrow disorders by allogeneic bone marrow transplantation following preparation with antihuman thymocyte serum and total body irradiation. Transplant Proc 13:241-244, 1981.

48. Hamilton BL, Bevan MJ and Parkman R. Anti-recipient cytotoxic T-lymphocyte precursors are present in the spleens of mice with acute graft-versus-host disease due to minor histocompatibility antigens. J Immunol 126:621-625, 1981.

49. Sheehey MS, Miller NJ, Rappeport JM, Gozes Y, Parkman R, Strom TB, Yunis EJ. A patient with post-hepatitis B immune deficiency: Non-specific helper factor partially restores the in vitro immune response. Vox Sanguinis 40:346-351, 1981.

50. Parkman R, Remold-O'Donnell E, Kenney DM, Perrine S, Rosen FS. Surface protein abnormalities in the lymphocytes and platelets from patients with the Wiskott-Aldrich syndrome. Lancet ii:1387-1390, 1981.

51. Hamilton BL and Parkman R. Kinetics of the anti-recipient cytotoxic cell response of mice with minor histocompatibility antigen graft-versus-host disease. J Immunol 128:376-379, 1982.

52. Leung DYM, Parkman R, Feller J, Wood N, Geha RS. Cell-mediated cytotoxicity against skin fibroblasts in atopic dermatitis. J Immunol 128:1736-1741, 1982.

53. Harmon WE, Parkman R, Lavin PT, Grupe WE, Ingelfinger JR, Yunis EJ, Levey RH. Comparison of cell-mediated lympholysis and mixed lymphocyte culture in the immunologic evaluation for renal transplantation. J Immunol 129:1573-1577, 1982.

54. Rappeport JM, Newburger PE, Goldblum RM, Goldman AS, Nathan DG, Parkman R. Allogeneic bone

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Robertson Parkman, M.D.marrow transplantation for chronic granulomatous disease. J Pediatr 101:952-955, 1982.

55. Saryan JA, Rappeport JM, Leung DYM, Parkman R, Geha R. Regulation of IgE synthesis in man: Mechanisms of increased IgE synthesis in acute graft versus host disease. J Clin Invest 71:556-564, 1983.

56. Hamilton BL and Parkman R. Acute and chronic graft versus host disease induced by minor histocompatibility antigens in mice. Transplantation 36:150-155, 1983.

57. Rappeport JM, Dunn MJ, Parkman R. Immature T lymphocytes in the peripheral blood of bone marrow transplant recipients. Transplantation 36(6):674-680, 1983.

58. Camitta B, O'Reilly RJ, Sensenbrenner L, Rappeport J, Champlin R, Doney K, August C, Hoffmann RG, Kirkpatrick D, Stuart R, Santos G, Parkman R, Gale RP, Storb R, Nathan D. Antithoracic duct lymphocyte globulin therapy of severe aplastic anemia. Blood 62(4):883-888, 1983.

59. Wesolowski J, Ault K, Houghton R, Parkman R. Heparin inhibition of antibody dependent complement mediated lysis. Exp Hematol 12:700-705, 1984.

60. Parkman R, Rappeport JM, Hellman S, Lipton J, Smith B, Ritz J, Geha R, Nathan DG. Busulfan and total body irradiation as anti-hematopoietic stem cell agents in the preparation of patients with congenital bone marrow disorders. Blood 64(4):852-857, 1984.

61. Parkman R, Remold-O'Donnell E, Cairns L, Rappeport JM, Cowan M, Ammann A, Kenney D, Potter N, Rosen F S. Immune abnormalities in patients lacking a lymphocyte surface glycoprotein. Clin Immunol Immunopathol 33:363-370, 1984.

62. Remold-O'Donnell E, Kenney DM, Parkman R, Cairns L, Savage B, Rosen FS. Characterization of a human lymphocyte surface sialoglycoprotein that is defective in Wiskott-Aldrich syndrome. J Exp Med 159:1705-1723, 1984.

63. First LR, Smith BR, Lipton J, Nathan DG, Parkman R, Rappeport JM Isolated thrombocytopenia after allogeneic bone marrow transplantation: existence of transient and chronic thrombocytopenic syndromes. Blood 65:368-374, 1985.

64. Smith BR, Parkman R, Lipton J, Nathan DG, Rappeport JM. Efficacy of a short course (four doses) of methotrexate following bone marrow transplantation for prevention of graft versus host disease. Transplantation 39(3):326-328, 1985.

65. Smith BR, Guinan EC, Parkman R, Ferrara J, Levey RH, Nathan DG, Rappeport JM. Efficacy of a cyclophosphamide-procarbazine-antithymocyte serum regimen for prevention of graft rejection following bone marrow transplantation for transfused patients with aplastic anemia. Transplantation, Brief Communication. 39(6):671-673, 1985.

66. Jadus MR and Parkman R. The selective growth of murine newborn-derived suppressor cells and their probable mode of action. J Immunol 136:783-792, 1986.

67. Parkman R. Current status of bone marrow transplantation in Pediatric Oncology. Cancer 58:569-572, 1986.

68. Parkman R. Clonal analysis of murine graft versus host disease. I. Phenotypic and functional analysis of T lymphocyte clones. J Immunol 136(10):3543-3548, 1986.

69. DeClerck Y, Draper V, Parkman R. Clonal analysis of murine graft versus host disease. II. Lymphokines that stimulate fibroblast proliferation and collagen synthesis in graft versus host disease. J Immunol 136(10):3549-3552, 1986.

70. Parkman R. The application of bone marrow transplantation to the treatment of genetic diseases. Science 232:1373-1378, 1986.

71. Kenney DM, Cairns L, Neustein H, Remold-O'Donnell E, Peterson JJ, Rosen FS, Parkman R. Morphological abnormalities in the lymphocytes of patients with the Wiskott-Aldrich syndrome. Blood 68(6):1329-1332, 1986.

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Robertson Parkman, M.D.72. Parkman R. Antibody-treated bone marrow transplantation for patients with severe combined immune

deficiency. Clin. Immunol. Immunopathol 40:142-146, 1986.73. Jadus MR, Schmunk G, Djeu JY, Parkman R. Morphology and lytic mechanisms of interleukin

3-dependent natural cytotoxic cells: tumor necrosis factor as a possible mediator. J Immunol 137(9):2774-2783, 1986.

74. Reisinger D and Parkman R. Molecular heterogeneity of a lymphocyte glycoprotein in immunodeficient patients. J. Clin. Invest. 79:595-599, 1987.

75. Parkman R, Champagne J, DeClerck Y, Cooper M, Draper V, Walker S. Cellular Interactions in graft-versus-host-disease. Transplant Proc 19:52-54, 1987.

76. Parkman R. Bone marrow transplantation and intensive care units: A need for integration. J Intensive Care Med 2:297-298, 1987.

77. Lenarsky CL, Weinberg K, Guinan E, Dukes PP, Barak Y, Ortega J, Siegel S, Williams K, Lazerson J, Weinstein H, Parkman R. Bone marrow transplantation for constitutional pure red cell aplasia. Blood 71(1):226-229, 1988.

78. Parkman R. Cyclosporine: GVHD and beyond. N Engl J Med 319:110-111, 1988.79. Lad P, Easton J, Nidzin H, Olson C, Goldberg B, Parkman R, Reisinger D, Learn D. A method for the

preparation of human mononuclear cells devoid of platelet contamination and its application to the evaluation of putative alpha receptors in asthmatic subjects. J. Immunol. Methods 110:193-202, 1988.

80. Avramis VI, Weinberg KI, Sato JK, Lenarsky C, Willoughby ML, Coates T, Ozkaynak MF, Parkman R. Pharmacology studies of 1--Arabinofuranosylcytosine in pediatric patients with leukemia and lymphoma after a biochemically optimal regimen of loading bolus plus continuous infusion of the drug. Cancer Res 249:241-247, 1989.

81. Bortin MM, Atkinson K, van Bekkum DW, Biggs JC, Dicke KA, Gale RP, Gluckman E, Good RA, Hoffmann RG, Horowitz MM, Kay HEM, Kersey JH, Marmont AM, Masaoka T, Jacobsen N, Kolb H-J, Parkman R, Ringden O, Rozman C, van Rood JJ, Zwaan FE. Factors influencing the risk of acute and chronic graft-versus-host disease in humans: a preliminary report from the IBMTR. Bone Marr Transplant 4:(Suppl. 1) 222-224, 1989.

82. Parkman R. Graft versus host disease: an alternative hypothesis. Immunol. Today 10:362-364, 1989.83. Petersen J, Church J, Gomperts E, Parkman R. Lymphocyte phenotype does not predict immune

function in HIV-1 infected pediatric patients. J Pediatr 115:944-948, 1989.84. Parkman R, Weinberg K, Kohn D, Sender L, Lenarsky C. Bone marrow transplantation in primary

disorders of the haematopoietic stem cell. Bone Marr Transplant 4:(Suppl. 4), 137-138, 1989.85. Ozkaynak MF, Nolta J, Parkman R. In vitro purging of human rhabdomyosarcoma cells using 4-

hydroperoxycyclophosphamide. Can Res 50:1455-1458, 1990.86. Weinberg K, Parkman R. Severe combined immune deficiency due to a specific defect in production of

interleukin-2. N Engl J Med 322:1718-1723, 1990.87. Ozkaynak MF, Lenarsky C, Kohn D, Weinberg K, Parkman R. Myobacterium avium-intracellulare

infections after allogeneic bone marrow transplantation in children. Am J Pediatr Hematol-Oncol 12:220-224, 1990.

88. Lenarsky C, Weinberg KI, Petersen J, Nolta J, Brooks J, Annett G, Kohn DB, Parkman R. Autologous bone marrow transplantation with 4-hydroperoxycyclophosphamide for patients with acute non-lymphoblastic leukemia in second remission. Bone Marrow Transplant. 6:425-429, 1990.

89. Lenarsky C and Parkman R. Bone marrow transplantation for the treatment of immune deficiency states. Bone Marrow Transplant. 6:361-369, 1990.

90. Parkman R. Human graft-versus-host disease. Immunodef Rev 2:253-264, 1991.91. Parkman R. Cytokines and T lymphocytes in pediatrics. J Pediatr 18:S21-S23, 1991.92. Piller F, Le Deist F, Weinberg KI, Parkman R, Fukuda M. Altered o-glycan synthesis in lymphocytes

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Robertson Parkman, M.D.from patients with Wiskott-Aldrich syndrome. J Exp Med 173:1501-1510, 1991.

93. Parkman R and Gelfand EW. Severe combined immunodeficiency disease, adenosine deaminase deficiency and gene therapy. Curr Opin Immunol 3:547-551, 1991.

94. Parkman R. Gene Therapy in the 1990s. Southern California Law Review 1991; 65:411-421. 95. Takano K, Kosi M, Thomas D, Fuss I, Srikanth MS, Nio M, Parkman R, and Atkinson J. A Miniature

Swine Model for Intestinal Transplantation. Transplant Proceed 1992; 24(3):1081-1082.96. Peterson M, Weinberg KI, Annett G, Church J, Gomperts E, Parkman R. Correction of Antigen-specific

T-lymphocyte function by recombinant cytokines. Children infected with human immunodeficiency virus type 1. J Ped 1992; 121(4):565-568.

97. Roberts WD, Weinberg KI, Kohn DB, Sender L, Parkman R, Lenarsky C. Granulocyte Recovery in Pediatric Marrow Transplant Recipients Treated With Ganciclovir For Cytomegalovirus Infection. Am J Ped Hem/Onc 15(3);320-323, 1993.

98. Lenarsky C, Weinberg K, Kohn, DB, Parkman R. Unrelated Donor Bone Marrow Transplantation For Wiskott Aldrich Syndrome. Bone Marrow Transplant 1993;12:145-147.

99. Weinberg K, Hershfield MS, Bastian J, Kohn D, Sender L, Parkman R, Lenarsky C. T Lymphocyte Ontogeny in Adenosine Deaminase Deficient Severe Combined Immune Deficiency Following Treatment With Polyethylene Glycol Modified Adenosine Deaminase. J Clin Invest. 1993;92:596-602.

100. Parkman R. Is chronic graft versus host disease an autoimmune disease? Curr Opin Immunol 1993;5:800-803.

101. Parkman R. Bone Marrow Transplantation for Immunodeficiency and Metabolic Diseases. Leukemia 1993;7:1100-1102.

102. Parkman R. Graft-versus-host disease and cytokine. Curr Opinion Hem 1993: 223-227.103. Clark JG, Hansen JA, Gertz MI Parkman R, Jensen L, Peavy HH. NHLBI workshop summary.

Idiopathic pneumonia syndrome after bone marrow transplantation. Am Rev Resp Dis 1993;147:1601-1605.

104. Bacchetta R, Bigler M, Touraine J-L, Parkman R, Tovo P-A, Abrams J, de Waal Malefyt R, de Vries JE. High levels of interleukin 10 Production in vivo are associated with tolerance in SCID patients transplanted with HLA mistmatched hematopoietic stem cells. J Exp Med 1994;179:493-502.

105. Hanley ME, Nolta JA, Parkman R, Kohn DB. Umbilical cord blood cell transduction by retroviral vectors: pre-clinical studies to optimize gene transfer. Blood Cells 20:1-8, 1994.

106. Bacchetta R, Parkman R, McMahon M, Weinberg K, Bigler M, de Vries JE, Grazia-Roncarolo M. Dysfunctional cytokine production by host-reactive T-cell clones isolated from a chimeric severe combined immunodeficiency patient transplanted with haploidentical bone marrow. Blood 85:1944-1953,1995.

107. Przepiorka D and Parkman R. Graft-versus-host disease and the graft-versus-leukemia effect: report of a workshop. BMT 15:S124-S127, 1995.

108. Kohn DB, Weinberg KI, Nolta JA, Heiss LN, Lenarsky C, Crooks GM, Hanley ME, Annett G, Brooks JS, El-Khoureiy A, Lawrence K, Wells S, Moen RC, Bastian J, Williams-Herman DE, Elder M, Wara D, BowenT, Hershfield MS, Mullen CA, Blaese RM, Parkman R. Engraftment of gene-modified umbilical cord blood cells in neonates with adenosine deaminase deficiency. Nat Med 1(10);1017-1023, 1995.

109. Parkman R and Weinberg KI. Age, the thymus, and T lymphocytes. N Eng J Med. 382:182-183, 1995 (Editorial).

110. Weinberg K, Annett G, Kashyap A, Lenarsky C, Forman SJ, Parkman R. The Effect of Thymic Function on Immunocompentence Following bone Marrow Transplantation. Biol Blood Marr Transplant 1:18-23, 1995.

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Robertson Parkman, M.D.111. Kohn DB, Weinberg KI, Parkman R. Gene Therapy for Immune Deficiency Syndromes-The Past, The

Present, The Future. The Immunologist 4(6):199-202, 1996.112. Dunbar C, Kohn DB, Karlsson S, Barton N, Brandy R, Cottler-Fox R, Esplin J, Leitman S, Lenarsky C,

Nolta JA, Parkman R, Pensiero P, Weinberg KI. Retroviral mediated transfer of the cDNA for human glucocerebrosidase into hematopoietic stem cells of patients with gaucher disease. A phase I study. Hum Gene Ther 7:231-253, 1996.

113. Sullivan KM, Walters MC, Patience M, Leisenring W, Buchanan GR, Castro O, Davies SC, Dickerhoff R, Eckman JR, Graham ML, OheneFrempong K, Powars D, Rogers ZR, Scott JP, Styles L, Vchinsky E, Wall DA, Wayne AS, Wiley J, Wingard J, Bunin N, CamittaB, Darbyshire PJ, Dinndorf P, Klingebiel T, McMahon L, Mentzer WC, Olivieri N, Orringer E, Parkman R, Roberts LAR, Sanders JE, Smith FO, Strob R. Collaborative study of marrow transplantation for sickle cell disease: aspects specific for transplantation of hemoglobin disorders. Bone Marrow Transplant 19(2):102-105, 1997.

114. Parkman R and Weinberg KI. Immunological reconstitution following bone marrow transplantation. Immunol Rev. 157:73-78, 1997.

115. Kohn DB and Parkman R. Gene therapy for newborns. FASEB J. 11, 635-639, 1997.116. Parkman R and Weinberg KI. The Di George Syndrome: Still an Enigma. J Ped 132;3-4, 1998.117. Wells WJ, Parkman R, Smogorzewska E, Barr M. Neonatal thymectomy: Does it affect immune function?

J Thorac Cardiovasc Surg 115: 1041-1046, 1998.118. Parkman R. Chronic graft-versus-host disease. Curr Opin Hematol 5(1):22-25, 1998.119. Wells WJ, Parkman R, Smogorzewska E, Barr M. Neonatal thymectomy: Does it affect immune

function? Thorac Cardiovasc Surg 115:1041-1046, 1998.120. Kohn DB, Hershfield MS, Carbonaro D, Shigeoka A, Brooks J, Smogorzewska EM, Barsky LW, Chan R,

Burotto F, Annett G, Nolta JA, Crooks G, Kapoor N, Elder M, Wara D, Bowen T, Madsen E, Snyder FF, Bastian J, Muul L, Blaese RM, Weinberg K, Parkman R. Selective accumulation of T lymphocytes containing a normal ADA gene four years after transplantation of transduced autologous umbilical cord blood CD34+ cells in ADA-deficient SCID neonates. Nat Med 4(7):775-780, 1998.

121. Kapoor N, Crooks G, Kohn DB, Parkman R. Hematopoietic Stem Cell Transplantation for Primary Immunodeficiencies. Semin Hematol 35(4):346-353, 1998.

122. Parkman R. The future of placental-blood transplantation. N Engl J Med 339(22);1628, 1998.123. Kapoor N, Chan R, Weinberg K, Burotto F, Parkman R. Defective Anti-Carbohydrate Antibody

Responses to Naturally Occurring Bacteria following Bone Marrow Transplantation. Biol Blood Marr Transplant 5:46-50, 1999.

124. Bolotin E, Annett G, Parkman R, Weinberg K. Serum levels of IL-7 in patients after bone marrow transplantation: relationship to clinical characteristics and lymphocyte count. Bone Marrow Transplant 23:783-788, 1999.

125. Rawlings SL, Crooks GM, Bockstoce D, Barsky LW, Parkman R, Weinberg KI. Spontaneous apoptosis in lymphocytes from patients with Wiskott-Aldrich Syndrome: correlation of accelerated cell death and attenuated Bcl-2 expression. Blood 94(11):3872-3882, 1999.

126. Parkman R, Weinberg K, Crooks C, Nolta J, Kapoor N, Kohn D. Gene therapy for adenosine deaminase (ADA) deficiency. Ann Rev Med 51:33-47, 2000.

127. Smogorzewska EM, Brooks J, Annett G, Kapoor N, Crooks GM, Kohn DB, Parkman R, Weinberg KI. T cell depleted haploidentical bone marrow transplantation for the treatment of children with severe combined immunodeficiency. Arch Immunol et Therap Exper 48:111-118, 2000.

128. George AA, Franklin J, Kerkof K, Shah A, Price M, Tsark E, Bockstoce D,Yao D, Hart N, Carcich S, Parkman R, Crooks GM, Weinberg K. Detection of leukemic cells in the CD34+, CD38- bone marrow progenitor population in children with ALL. Blood 97: 3925-3930, 2001.

129. Weinberg KI, Kapoor N, Shah AJ, Crooks GM, Kohn DB, Parkman R. Hematopoietic stem cell

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Robertson Parkman, M.D.transplantation for severe combined immune deficiency. Curr Allergy Asthma Rep 1(5):416-420, 2001.

130. Shah AJ, Kapoor N, Weinberg KI, Crooks GM, Kohn DB, Lenarsky C, Kaufman F, Epport K, Wilson K, Parkman R. Second hematopoietic stem cell transplantation in pediatric patients: overall survival and long-term follow-up. Biol Blood Marr Transplant 8(4):221-227, 2002.

131. Parkman R. Antigen-specific immune function after hematopoietic stem cell transplantation. Biol Blood Marr Transplant 9:287-291, 2003.

132. Parkman R. Getting a handle on graft-versus-host disease. N Engl J Med 350(6):614-615, 2004.133. Shah AJ, Lenarsky C, Kapoor N, Crooks GM, Kohn DB, Parkman R, Epport K, Wilson K, Weinberg K.

Busulfan and cyclophosphamide as a conditioning regimen for pediatric acute lymphoblastic leukemia patients undergoing bone marrow transplantation. J Pediatr Hematol Oncol 26(2):91-97, 2004.

134. Shah AJ, Kapoor N, Crooks GM, Parkman R, Weinberg KI, Wilson K, Kohn DB. Successful hematopoietic stem cell transplantation for Niemann-Pick Disease Type B. Pediatrics 116(4):1022-1025, 2005.

135. Chan B, Wara D, Bastian J, Hershfield MS, Bohnsack J, Azen CG, Parkman R, Weinberg K, Kohn DB. Long-term efficacy of enzyme replacement therapy for adenosine deaminase (ADA)-deficient sever combined immunodeficiency (SCID). Clin Immunol 117(2):133-143, 2005.

136. Engel BC, Podsakoff GM, Ireland JL, Smogorzewska EM, Carbonaro DA, Wilson K, Shah AJ, Kapoor N, Sweeeney M, Borchert M, Crooks GM, Weinberg KI, Parkman R, Rosenblatt HM, Wu SQ, Hershfield MS, Candotti F, Kohn DB. Prolonged pancytopenia in a gene therapy patient with ADA-deficient SCIA and Trisomy 8 Mosaicism- a case report. Blood 109(2):503-6. 2006.

137. Parkman R, Cohen G, Carter SL, Weinberg KI, Masinsin B, Guinan E, Kurtzberg J, Wagner JE, Kernan NA. Successful immune reconstitution decreases leukemic relapse and improves survival in recipients of unrelated cord blood transplantation. Biol Blood Marrow Transplant 12(9):919-927, 2006.

138. Cohen G, Carter SL, Weinberg KI, Masinsin B, Guinan E, Kurtzberg J, Wagner JE, Kernan NA, Parkman R. Antigen-specific T-lymphocyte function after cord blood transplantation. Biol Blood Marrow Transplant. 12:1335-42, 2006.

139. Shah AJ, Kapoor N, Crooks GM, Weinberg KI, Azim HA, Killen R, Kuo L, Rushing T, Kohn DB, Parkman R. The effects of Campath 1H upon graft-versus-host disease, infection, relapse, and immune reconstitution in recipients of pediatric unrelated transplants. Biol Blood Marrow Transplant 13:584-593, 2007.

140. Parkman R. Antigen-specific immunity following hematopoietic stem cell transplantation. Blood Cells Mol Dis, 40(1):91-93, 2008.

141. Griffith LM, Cowan MJ, Kohn DB, Notarangelo LD, Puck JM, Schultz KR, Buckley RH, Eapen M, Kamani NR, O'Reilly RJ, Parkman R, Roifman CM, Sullivan KE, Filipovich AH, Fleisher TA, Shearer T. Allogeneic hematopoietic cell transplantation for primary immune deficiency diseases: current status and critical needs. J Allergy Clin Immunol 122(6):1087-96,2008.141. Shah AJ, Kapoor N, Cooper RM, Crooks GM, Lenarsky C, Abdel-Azim H, Wu SQ, Wilson K, Weinberg

KI, Parkman R, Kohn DB. Pre- and post-natal treatment of hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer 52(1):139-142, 2009.

142. Lin M, Epport K, Azen C, Parkman R, Kohn DB, Shah AJ. Long-term neurocognitive function of pediatric patients with severe combined immune deficiency (SCID): pre- and post-hematopoietic stem cell transplant (HSCT). J Clin Immunol 29(2):231-7, 2009.

143. Reiff A, Krogstad P, Moore S, Shaham B, Parkman R, Kitchen C, Weinberg K. Study of thymic size and function in children and adolescents with treatment refractory systemic sclerosis eligible for immunoablative therapy. Clin Immunol 133:295-302, 2009.

144. Rappeport JM, O’Reilly, Kapoor N, Parkman R. Hematopoietic stem cell transplantation for severe combined immune deficiency or what the children have taught us. Immunol Allergy Clin North Am

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Robertson Parkman, M.D.30(1):17-30, 2010.

145. Taylor PL, Barker RA, Blume KG, Cattaneo E, Colman A, Deng H, Edgar H, Fox IJ, Gerstle C, Goldstein LS, High KA, Lyall A, Parkman R, Pitossi FJ, Prentice ED, Rooke HM, Sipp DA, Srivastava A, Stayn S, Steinberg GK, Wagers AJ, Weissman IL. Patients beware: commercialized stem cell treatments on the web. Cell Stem Cell 7(1):43-9, 2010.

146. Reiff A, Shaham B, Weinberg KI, Crooks GM, Parkman R.  Anti-CD52 antibody mediated immune ablation with autologous immune recovery for the treatment of refractory juvenile polymyositis.  J Clin Immunol 31(4):615-22, 2011. PMID:21541793

147. Candotti F, Shaw KL, Muul L, Carbonaro D, Sokolic R, Choi C, Schurman SH, Garabedian E, Kesserwan C, Jagadeesh GJ, Fu PY, Gschweng E, Cooper A, Tisdale JF, Weinberg KI, Crooks GM, Kapoor N, Shah A, Abdel-Azim H, Yu XJ, Smogorzewska M, Wayne AS, Rosenblatt HM, Davis CM, Hanson C, Rishi RG, Wang X, Gjertson D, Yang OO, Balamurugan A, Bauer G, Ireland JA, Engel BC, Podsakoff GM, Hershfield MS, Blaese RM, Parkman R, Kohn DB. Gene therapy for adenosine deaminase-deficient severe combined immune deficiency: clinical comparison of retroviral vectors and treatment plans. Blood 120:3635-3646, 2012. PMID: 22968453.

148. Parkman R. A 2-hit model for chronic GVHD. Blood 122(5):623-624, 2013. PMID:23908441149. Reiff A, Weinberg KI, Triche T, Masinsin B, Mahadeo KM, Lin CH, Brown D, Parkman R. T lymphocyte

abnormalities in juvenile systemic sclerosis patients. Clin Immunol 149(1):146-155, 2013. PMID: 23994768.

150. Parkman R. Mixed Chimerism: Good News or Bad News. Biol Blood Marrow Transplant 20(6) 750-1, 2014. PMID:24732782

151. Mahadeo KM, Masinsin B, Kapoor N, Shah AJ, Abdel-Azim H, Parkman R.  Immunological Resolution of Human Chronic Graft-versus-Host Disease.  Biol Blood Marrow Transplant, 20(10) 1508-15, 2014 PMID:24979733

NOT PEER REVIEWED1. Griffith LM, Cowan MJ, Kohn, DB, Notarangelo LD, Puck JM, Schultz KR, Buckley RH, Eapen M,

Kamani NR, O’Reilly RJ, Parkman R, Roifman CM, Sullivan KE, Filipovich AH, Fleisher FA, Shearer WT. Allogeneic hematopoietic cell transplantation for primary immune deficiency diseases: Current status and critical needs. J Allergy Clin Immunol 122:1087-1096, 2008.

BOOKS, CHAPTERS, INVITED ARTICLES1. Parkman R. Neonatology. In Manual of Pediatric Therapeutics, J. Graef and T. Cone (eds), Little Brown &

Co., pp 99-119, 1974.2. Alper CA and Parkman R. Serum protein and other genetic markers of the blood. In Hematology of

Infancy and Childhood, D.G. Nathan and F.A. Oski (eds), Saunders, Philadelphia, pp 818-849, 1974.3. Gelfand EW, Parkman R and Rosen FS. Transplantation in severe combined immunodeficiency

disease with HL-A identical bone marrow. In Proceedings of the Second International Workshop on Primary Immunodeficiency Disease in Man, D. Gergsma (ed), Birth Defects Institute, National Foundation, pp 409-416, 1975.

2. Gelfand EW, Parkman R and Rosen FS. Immunologic unresponsiveness with the presence of autolymphocytotoxins. In Proceedings of the Second International Workshop on Primary Immunodeficiency Disease in Man, D. Bergsma, (ed), Birth Defects Institute, National Foundation, pp 158-162, 1975.

3. Parkman R, Gelfand EW and Rosen FS. Attempted immunological reconstruction of patients with combined immune deficiency syndrome with bone marrow transplantation from histo-incompatible

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Robertson Parkman, M.D.donors. In Proceedings of the Second International Workshop on Primary Immunodeficiency Disease in Man. D. Bergsma (ed), Birth Defects Institute, National Foundation, pp 417-420, 1975.

6. Littman BH, Rocklin RE, Parkman R and David JR. Combination transfer factor-amphotericin B therapy in a case of chronic mucocutaneous candidiasis: A controlled study. In Transfer Factor. Basic Properties and Clinical Applications. Academic Press, Inc., New York, pp 495-501, 1976.

7. McCaffrey RP, Harrison TA, Kung PC, Parkman R, Silverstone AE and Baltimore D. Terminal deoxynucleotidyl transferase in normal and neoplastic hematopoietic cells. In Modern Trends in Human Leukemia II. R. Neth (ed), J.F. Lehmans Verlag, pp 503-513, 1976.

8. Parkman R. Treatment of immune deficiency states with organ transplantation. In Progress in Clinical Immunology, Vol. 3. (R. Schwartz, editor). Grune and Stratton, New York, pp 85-102, 1976.

9. Parkman R. Immunology. In Diseases of the Newborn. (ed.) M.E. Avery and A. Schaffer, Saunders, Philadelphia, pp 764-773, 1977.

10. Parkman R. The immunopathology of marrow failure. In Clinics in Hematology. E.D. Thomas (ed.), W.B. Saunders Company, Ltd., London, pp 475-486, 1978.

11. Geha R, Twarog F, Rappeport JM, Parkman R. IgE levels following allogeneic bone marrow transplantation. In New Approaches to the Management of Allergic Diseases. L. Lichenstein, G. Glisch, S.S. Krager-AG (ed.). Basal Switzerland Monographs in Allergy, pp 81-85, 1979.

12. Parkman R, Rappeport JM and Rosen FS. Correction of primary immunodeficiencies by allogeneic bone marrow transplantation. In Primary Immunodeficiencies. M. Seligman and W.H. Hitzig (eds.), Elsevier/North-Holland Biomedical Press, pp 413-418, 1980.

13. Parkman R, Rich RR, Slavin S and Strober S. Workshop Report: Suppressor cells and GVHD. In Biology of Bone Marrow Transplantation. R. Gale (ed.) Academic Press, Inc., New York, pp 285-289, 1980.

14. Alter BP, Rappeport JM, Parkman R. The bone marrow failure syndromes. In Hematology of Infancy and Childhood. F.H. Oski and D.G. Nathan (eds.), W.B. Saunders, Philadelphia, pp 168-250, 1981.

15. Parkman R, Geha R, Leung DYM, Keohan ML, Dunn MJ and Rappeport JM. Immunoregulatory abnormalities following bone marrow transplantation. In Regulation of the Immune Response. J.F. Mohn and P.L. Orga. (eds.), S Karger, AG Basel, 355-343, 1982.

16. Parkman R. Treatment of human immunodeficiencies. Clin. Immun. Rev. 1:375-408, 1982.17. Sullivan K and Parkman R. The pathophysiology and treatment of graft versus host disease. In Clinics

in Hematology 12(3):775-789, 1992. 18. Rappeport JM, Smith B, Parkman R and Rosen F. Application of bone marrow transplantation in

genetic diseases. In Clinics in Hematology. 12(3):755-773,1983.19. Parkman R, Rappeport JMR, Rosen FS and Nathan D. Bone marrow transplantation for lymphoid and

immunodeficiencies. UCLA Symposia. In Recent Advances in Bone Marrow Transplantation. R.P. Gale (ed.), A.R. Liss, Inc., New York, Vol. 7, pp 173-183, 1983.

20. Parkman R. Genetic disorders. In Clinical Bone Marrow Transplantation. K.G. Blume, L.D. Petz (eds.), Churchill Livingstone (Pubs.), Chapter 9, 241-270, 1983.

21. Parkman R, Remold-O'Donnell E, Kenney DM and Rosen R.S. A new class of immunodeficiencies. In Birth Defects: Original Article Series. 19:(3):97-99, 1983.

22. Parkman R. Preparation for bone marrow transplantation. In Springer Seminars in Immunopathology. Y. Borel (ed.), Springer-Verlag New York, Inc. (Pubs.), Vol. 7(1):59-67, 1984.

23. Parkman R. Inflammatory and Immunodeficiency Disorders. In Childrens Hospital: Pediatric Therapeutics. Little, Brown and Company (Pubs.), Chapter 18, 463-478, 1984.

24. Rappeport JM and Parkman R. Bone marrow transplantation for genetic diseases. In Bone Marrow and Organ Transplantation. S. Slavin (ed.), Elsevier Science Company, Inc. (Pubs.), Chapter A4, 55-66, 1984.

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Robertson Parkman, M.D.25. Parkman R. T Lymphocyte defects. In Clinics In Immunology and Allergy. F.S. Rosen, (ed.), W.B.

Saunders Company (Pubs.), Chapter 7, 5:325-338, 1985.26. Nyhan WL, Page T, Gruber HE, Parkman R. Bone Marrow Transplantation in Lesch-Nyhan Disease. In

Birth Defects: Original Article Series. W. Krivit, N.W. Paul (eds.), Alan R. Liss (Pub.), 22(1):113-117, 1986.

27. Nyhan WL, Parkman R, Page T, Gruber HE, Pyati J, Jolly D, Friedmann T. Bone marrow transplantation in Lesch-Nyhan disease. In Purine and Pyrimiding Metabolism in Man. V. W. L. Nyhan, L. Thompson and R.W.E. Watts (Eds.), Plenum Publishing Corp., pp. 167-170, 1986.

28. Parkman R. Chronic graft versus host disease is an autoimmune disease. In Progress in Bone Marrow Transplantation. UCLA Symposia on Molecular and Cellular Biology. Vol. 53, pp. 13-18, 1986.

29. Parkman R, Champagne J, Cooper M, Draper V, Walker S. The role of autoreactive T lymphocytes in graft-versus-host-disease (GVHD). In Recent Advances and Future Directions in Bone Marrow Transplantation. S.J. Baum, G.W. Santos, and F. Takaku (eds), Springer-Verlag, New York, pp 158-160, 1987.

29. Parkman R, DeClerck Y, Champagne J, Walker S. Chronic graft-versus-host-disease is an autoimmune disease. In Progress in Bone Marrow Transplantation. R.P. Gale and R. Champlin (eds), Alan R. Liss, Inc., New York, pp 497-504, 1987.

31. Weinberg K, Parkman R. The interface between immunodeficiency and pediatric cancer. In Principles and Practice of Pediatric Oncology. P.A. Pizzo and D.G. Poplack (Eds.), J. B. Lippincott Co., Chapter 4, pp 65-79, 1988.

32. Parkman R. Future perspectives for bone marrow transplantation in pediatrics. In: Contemporary Issues in Pediatric Transfusion Medicine. Sacher, R.A. and Strauss, R. (eds.) American Association of Blood Banks, Arlington, VA., pp. 93-99, 1989.

33. Parkman R. Transplantation immunity. Curr. Opinion Pediatr 1:44-47, 1989.34. Parkman R, Weinberg K. Inherited Immunodeficiency Diseases. In: Hematology, Fourth Edition.

Williams, W.J., Beutler, E., Erslev, A.J., Lichtman, M.A. (eds). McGraw-Hill, Inc, New York, Chapter 111, pp 967-972, 1990.

35. Lenarsky C, Kohn DB, Weinberg KI and Parkman R. Bone marrow transplantation for genetic diseases. In: Hematology/Oncology Clinics of North America. Vol. 4 S. Forman (ed.), W.B. Saunders Company, Philadelphia, PA., pp 589-602, 1990.

36. Parkman R. Clonal analysis of graft-vs.-host disease. In: Hematology/Volume 12 Graft-Vs.-Host Disease. Burakoff, Deeg, Ferrara, Atkinson (eds.), Marcel Dekker, Inc., pp 51-60, 1990.

37. Lenarsky CL, Kohn DB, Parkman R. Bone marrow transplantation for genetic diseases. In: Bone Marrow Transplantation. R. Champlin (ed.). Kluwer Boston, Inc., pp 167-184, 1990.

38. Parkman R, Lenarsky C, Kohn D, Sender L and Weinberg K. Bone marrow transplantation for immunodeficiency states. In: New Strategies in Bone Marrow Transplantation, UCLA Symposia on Molecular & Cellular Biology. Gale, R.P. and Champlin, R. (eds.), Wiley-Liss, Inc., New York, NY, pp 229-235, 1991.

39. Parkman R. Graft-versus-host disease. In: Annual Review of Medicine, Vol. 42. W.P. Creger (ed.), Annual Reviews, Inc., Palo Alto, CA, pp 189-197, 1991.

40. Parkman R. Bone marrow transplantation. In: Encyclopedia of Human Biology. Dulbecco, R. (ed.), Academic Press, Inc., pp. 791-798, 1991.

41. Parkman R. The biology of bone marrow transplantation for severe combined immune deficiency. In: Advances in Immunology, Vol. 49. Dixon, F.J. (ed.), Academic Press, Inc., Orlando, FL, pp. 381-410, 1991.

42. Parkman R. Organ transplantation as therapy for genetic diseases. In: Therapy for Genetic Diseases. T. Friedman (ed.), Oxford University Press, Oxford, UK, pp. 95-104, 1991.

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Robertson Parkman, M.D.43. Parkman R. Bone marrow transplantation for genetic diseases. Pediatric Annals 1991;12(20):677-681.44. Parkman R. Graft-versus-host reaction. In: Encyclopedia of Immunology. I. Roitt and P.J. Delves

(eds.), W.B. Saunders Company, Orlando, FL, 1991.45. Parkman R. Transplantation biology. In: Hematology: Basic Principles and Practices. Benz,

E.J.,Cohen, H.J., Furle, B., Hoffman, R., Shattil, S.J. (eds.), Churchill Livingstone, Inc., New York, NY, 1991.

46. Parkman R. Allergy, immunology, and related disorders. Current Opinion in Peds. Volume 4 pp. 989-990, 1992.

47. Parkman R. Graft Versus Host Disease and Cytokines. Current Opinion in Hem. Adamson, J.W. (ed) CS, UK. pp.223-227, 1993.

48. Parkman R. Immunological reconstitution following bone marrow transplantation. In: Bone Marrow Tansplantation Forman, SJ., Thomas, E.D. and Blume, K.G. (eds) Blackwell Sci. Pub., Inc., Cambridge, MA. Chapter 36 pp 504-512, 1995.

49. Parkman R. Bone marrow transplantation for congenital metabolic disease. In: Clinical Bone Marrow Transplant Atkinson, J. (ed) Cambridge Univ. Press, UK. 1995.

50. Parkman R, Crooks G, Kohn DB, Lenarsky C and Weinberg KI. Bone Marrow Transplantation for Metabolic Diseases. Tech & Biol Components Marr Transplant, 87-96;1995.

51. Parkman R and Crooks G. Bone Marrow Transplantation for Metabolic Diseases. Immunology & Allergy Clinical of North America 16:429-438, 1996.

52. Kohn DB, Crooks G, Nolta J, Kapoor N, Weinberg K and Parkman R. Gene Therapy with Cord Blood Hematopoietic Stem Cells. Cord Blood Transplantation. P. McCurdy (ed), 1998.

53. Parkman R and Weinberg K. Immunological Reconstitution following Hematopoietic Stem Cell Transplantation. Hematopoietic Cell Transplantation, 2nd edition, Thomas, ED, Blume KG and Forman SJ (ed) Blackwell Publishing, Inc., Cambridge, MA. Chapter 60, pp704-711, 1999.

54. Shah A, Kapoor N, Crooks G, Kohn DB, Weinberg KI and Parkman R. Allogeneic hematopoietic stem cell transplantation for metabolic diseases. In: Clinical Bone Marrow and Blood Stem Cell Transplantation. Atkinson K, Champlin R, Ritz J, Fibbe WE, Ljungman P, Brenner MK (eds.), Cambridge University Press, NY. Chapter 63, pp 963-973, 2004.

55. Parkman R and Weinberg K. Immune reconstitution following hematopoietic cell transplantation. In: Thomas’ Hematopoietic Cell Transplantation, 3rd Edition, Blume KG, Forman SJ, Applebaum RF (eds.), Blackwell Publishing, Inc., Cambridge, Massachusetts, 2004.

56. Parkman R. Primary immunodeficiences. In: Measuring Immunity, Lotze MT, Thomson AW (eds.), Elsevier Pub., London, 2005.

57. Parkman R and Weinberg K. Immune reconstitution following hematopoietic cell transplantation. In:Thomas’ Hematopoietic Cell Transplantation, 4th Edition, Appelbaum FR, Forman SJ, Negrin RS, Blume KG (eds.), Blackwell Publishing, Inc., Cambridge, Massachusetts, Chapter 17, pp 222-231, 2009.

58. Shah A, Kapoor N, Abdel-Azim H, Parkman R. Immune reconstitution after haploidentical hematopoietic stem cell transplantation. In: Bone Marrow Transplantation Across Major Genetic Barriers, Reisner Y, Martelli MF (eds.), World Scientific Publishing Co. Pte. Ltd., Singapore, 2010.

59. Rappeport JM, O’Reilly RJ, Kapoor N, Parkman R. Hematopoietic stem cell transplantation for severe combined immune deficiency or what the children have taught us. In: Immunodeficiency, Infection, and Stem Cell Transplantation, Berliner M (ed.), W.B. Saunders, Philadelphia, PA, 2011.

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