curriculum vitae (word).doc

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K.M. Ziada, M.D. curriculum vitae Khaled M. Ziada, MD, FACC, FSCAI Assistant Professor, Division of Cardiovascular Medicine Associate Director, Interventional Cardiology FellowshipProgram Gill Heart Institute, University of Kentucky Director, Cardiac Catheterization Laboratory Lexington VA Medical Center, Lexington, Kentucky Home Address 3136 Hemingway Lane Lexington, KY 40513 Phone: 859-296-5631 Professional Address University of Kentucky Medical Center Gill Heart Institute Division of Cardiovascular Medicine 900 South Limestone Street 326 C.T. Wethington Bldg. Lexington, KY 40536-0200 Office Phone: 859-323-6195 Office Fax: 859-323-6475 E-mail address: [email protected] Place & Date of birth Alexandria, Egypt, on September 5, 1965 Page 1 of 22

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Page 1: Curriculum Vitae (word).doc

K.M. Ziada, M.D. curriculum vitae

Khaled M. Ziada, MD, FACC, FSCAIAssistant Professor, Division of Cardiovascular Medicine

Associate Director, Interventional Cardiology FellowshipProgramGill Heart Institute, University of Kentucky

Director, Cardiac Catheterization LaboratoryLexington VA Medical Center, Lexington, Kentucky

Home Address

3136 Hemingway LaneLexington, KY 40513Phone: 859-296-5631

Professional Address

University of Kentucky Medical CenterGill Heart InstituteDivision of Cardiovascular Medicine900 South Limestone Street326 C.T. Wethington Bldg.Lexington, KY 40536-0200Office Phone: 859-323-6195Office Fax: 859-323-6475E-mail address: [email protected]

Place & Date of birth

Alexandria, Egypt, on September 5, 1965

Marital status

Married since January 1992Spouse: Hala A YacoutChildren: Mahmoud (born 1993) and Nada (born 1997)

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Certifications

US ECFMG

ECFMG # 440-459-6FMGEMS Jul '89 clinical sciences 82%

Jul '91 basic sciences 83%Permanent validation of ECFMG certificate Jan '95USMLE step 2 Oct ’98 84%USMLE step 1 Oct ’99 84%USMLE step 3 Dec ’01 83%

American Board of Internal Medicine Certification

Board certified Internal Medicine Oct ’02Board Certified Cardiovascular Medicine Nov’04Board Certified Interventional Cardiology Nov’05

Medical Licensure

- Permanent license in Egypt - since Mar1990 (license # 98674)- Permanent Ohio license – since Dec 2002 (license # 82065)- Permanent Kentucky license – since June 2004 (license # 38725)

Education

Sep '79 - May '81Port Said High School, Zamalek, Cairo

Jun '81 - Jan '82General Certificate of Education, University of London

Oct '82 - Dec '88M.B. B.ch Degree (with honors), School of Medicine, Cairo University

May '91 - Nov '93Master Degree (with honors) in Cardiovascular Medicine,School of Medicine, Cairo University

Professional Experiences

Mar '89 - Feb '90Flexible internship, Cairo University Hospitals, Cairo

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Mar '90 - Sep '91Resident, Department of Internal Medicine, Helmeya Military Hospital, Cairo

Sep '91 - Sep '94Resident of Cardiovascular Medicine, Cairo University Hospitals, Cairo

Jun ‘95 - Feb ‘98Research fellow, Intravascular Ultrasound Imaging Core Laboratory, Department of Cardiovascular Medicine, The Cleveland Clinic Foundation.

Jul ‘98 - Jun ‘00Fellow, Interventional Cardiology, Department of Cardiovascular Medicine, the Cleveland Clinic Foundation.

Jul ’00 – Jun ‘02Resident, Department of Internal Medicine, The Cleveland Clinic Foundation.

Jul ’02 – Jun ‘04Fellow, Department of Cardiovascular Medicine, The Cleveland Clinic Foundation.

Oct ’04 – -Assistant Professor of Medicine, Division of Cardiovascular Medicine, University of Kentucky, Lexington, KY.-Attending Cardiologist, VA Medical Center, Lexington, KY

Research and Grant Activity

2004 – Current

Site principal investigator at the University of Kentucky and the VA Medical Center for numerous multi-center clinical trials (with emphasis on intravascular ultrasound imaging and percutaneous coronary interventions)

1. A Double-Blind, Randomized Comparator-Controlled Study in subjects with Type II Diabetes Mellitus Comparing the Effects of Pioglitazone HCI versus Glimepiride on the Rate of Progression of Coronary Atheroslerotic Disease as Measured by Intravascular Ultrasound (PERISCOPE)

2. Randomized, multi-center, double-blind, placebo-controlled, two-arm parallel

group trial of rimonabant 20-mg, for inhibition of atheroslerosis progression assessed by IVUS, in overweight patients with clustering risk factors (STRADIVIRIUS).

3. A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety of SCH 530348 in Subjects Undergoing Non-Urgent Percutaneous Coronary Intervention (Thrombin Receptor Antagonist for Clinical Event reduction over standard concomitant therapies in PCI (Transcendence- PCI).

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4. A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of SCH 530348 in Addition to Standard of Care in Subjects With a History of Atherosclerotic Disease: Thrombin Receptor Antagonist in Secondary Prevention of Atherothrombotic Ischemic Events (TRA 2°P - TIMI 50)

5. Randomized, Multinational, Multicenter, Double-Blind, Placebo-Controlled, Two-Arm Parallel Group Trial of Once Daily Rimonabant 20 mg for Reducing the Risk of Major Cardiovascular Events in Abdominally Obese Patients With Clustering Risk Factors (CRESCENDO)

6. Study of Coronary Atheroma by Intravascular Ultrasound: Effect of Rosuvastatin versus Atorvastatin (SATURN)

7. A Prospective, Randomized, Double-Blind, Double-Dummy, Parallel-Group, Multicenter, Event-Driven, Non-Inferiority Study Comparing the Efficacy and Safety of Once-Daily Oral Rivaroxaban (BAY 59-7939) With Adjusted-Dose Oral Warfarin for the Prevention of Stroke and Non-Central Nervous System Systemic Embolism in Subjects With Non-Valvular Atrial Fibrillation (ROCKET-AF).

Principal Investigator for clinical research projects conducted locally

1. Impact of drug-eluting stents on outcomes of patients with end-stage renal disease undergoing percutaneous coronary revascularization.

2. Impact of use of drug-eluting stents versus bare-metal stents in octogenarians

3. Prevalence of major cardiac events in patients undergoing non-cardiac surgery after drug eluting stent implantation

4. Long term cardiovascular outcomes in patients undergoing renal artery stenting

Investigator initiated research funded by the GCRC

1. The Association between Obesity and Peripheral Artery Disease

Jan ’95- Jun ‘98

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Reseearch fellow in the intravascular ultrasound core laboratory at the Cleveland Clinic Foundation, with numerous publications, abstracts, national and international presentations (vide infra)

May '93 - Jan '95Central Office Physician in the Egyptian National Hypertension Project, a joint research conducted by the Cairo University, the Egyptian Ministry of Health, Johns Hopkins Medical School, and NIHLBI.

Nov '91 - Jun '93Master Degree thesis on " Role of transesophageal echocardiography in the diagnosis of infective endocarditis" (abstract presented in the 20th annual meeting of the Egyptian Society of Cardiology, May ‘94)

Editorial Activity

Reviewer for Circulation, Journal of American College of Cardiology, American Journal of Cardiology, American Heart Journal, British Medical Journal, Clinical Cardiology, Atherosclerosis and Clinical Nephrology

Assistant reviewer for Journal of American Medical Association, Lancet, New England Journal of Medicine

Speaking Engagements

1. Introduction to Intravascular Ultrasound Imaging (2 parts). Update on Cardiovascular Technologies. March 1996, Commanche Memorial Hospital, Lawton, OK.

2. The role of intravascular ultrasound imaging in contemporary stenting. Annual meeting of the New Delhi Branch , Indian Society of Cardiology. August 1997, Batra Hospital, Delhi, India.

3. Intravascular utlrasound imaging and coronary stenting: insights in stent restenosis. Cleveland Clinic department of radiation oncology research retreat, June 2000.

4. Role of intravascular ultrasound in diagnosis and follow-up of transplant coronary disease. Heart Failure Summit, October 2000, Cleveland, OH.

5. Carotid stenting: the current state of affairs. Case Western Reserve University, Division of Cardiology Grand Rounds, December 2003, Cleveland, OH.

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6. Diagnosis & Management of Acute Myocardial Infarction. University of Kentucky, Family Medicine, February 2005, Lexington, KY.

7. “Intravascular Ultrasound Imaging: Towards a Better Understanding of Arterial Disease”. University of Kentucky Cardiovascular Seminar Series, December 16, 2005, Lexington, KY.

8. “PCI for the Unprotected Left Main Trunk: Is It Ready for Prime Time?” Dar Al-Fouad Hospital 1st International Cardiology Meeting, April 2006, Cairo, Egypt

9. “Novel Approaches to Vulnerable Plaque Imaging”. Dar Al-Fouad Hospital 1st International Cardiology Meeting, April 2006, Cairo, Egypt

10. Acute Myocardial Infarction: Early Diagnosis and Treatment. University of Kentucky, Family Medicine, May, 2006, Lexington, KY.

11. Cardiology Update 2006. University of Kentucky, Family Medicine, May, 2006, Lexington, KY.

12. Cardiac Cathetherization. University of Kentucky, Internal Medicine Noon Conference, October 3, 2006.

13. Unprotected Left Main PCI Current Status. The Egyptian Society of Cardiology 34th Annual Scientific Meeting, Cairo, Egypt, February 20-23, 2007.

14. Noncardiac Surgery After Recent Drug-Eluting Stent Placement: What Do We Do Now? ACC Annual Meeting, New Orleans, LA, March 24-27, 2007.

15. Luminography and Its Limitations. ACC Annual Meeting, New Orleans, LA, March 24-27, 2007.

16. Antithrombotics and PCI – What you really need to know., Abbott Vascular Fellows Program, Washington, D.C., June 2, 2007.

17. IVUS Basics, Abbott Vascular Fellows Program, Washington, D.C., June 3, 2007.

Publications

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Manuscripts

1. Moliterno DJ, Ziada KM. The safety and efficacy of glycoprotein IIb/IIIa inhibitors for primary angioplasty: more options to choose and more time to decide. J Am Coll Cardiol. Feb 5 2008;51(5):536-537.

2. Weathers LW, Ziada KM. Drug-eluting stents in patients with end-stage renal disease. Minerva Cardioangiol. Feb 2008;56(1):117-125.

3. Nissen, SE, Nicholls SJ, Wolski K, Rodes-Cabau J, Cannon CP, Deanfield JP, Despres JP, Kastelein JJ, Steinhubl SR, Kapadia S. Yasin M, Ruzyllo W, Gaudin C, Job B, Hu B, Bhatt DL, Lincoff AM, Tuzcu EM: STRADIVARIUS investigators. Effect of rimonabant on progression of atherosclerosis in patients with abdominal obesity and coroanry artery disease: the STRADIVARIUS randomized controlled trial. JAMA. 2008 Apr 2;299 (13);1547-60.

4. Nissen SE, Nicholls SJ, Wolski K, Nesto R, Kupfer S, Perz A, Jure H, De Larochelliere R, Staniloae CS, Mavromatis K, Saw J, Hu B, Lincoff AM, Tuzcu EM: PERISCOPE investigators. Comparison of pioglitazone vs glimepiride on progression of coroanry atherosclerosis in patients with type 2 diabetes: the PERISCOPE randomized controlled trial. JAMA. 2008 Apr 2; 299 (13); 1561-73.

5. Ziada KM. Coronary revascularization in end-stage renal disease. Curr Cardiol Rep. Sep 2007;9(5):389-395.

6. Mukherjee D, Topol EJ, Moliterno DJ, et al. Extracardiac vascular disease and effectiveness of sustained clopidogrel treatment. Heart. Jan 2006;92(1):49-51.

7. Ellis K, Ziada KM, Vivekananthan D, et al. Transthoracic echocardiographic predictors of left atrial appendage thrombus. Am J Cardiol. Feb 1 2006;97(3):421-425.

8. Gurm HS, Breitbart Y, Vivekanathan D, et al. Preprocedural statin use is associated with a reduced hazard of postprocedural myonecrosis in patients undergoing rotational atherectomy--a propensity-adjusted analysis. Am Heart J. May 2006;151(5):1031 e1031-1036.

9. Das P, Ziada KM, Steinhubl SR, et al. Heparin-induced thrombocytopenia and cardiovascular diseases. Am Heart J. Jul 2006;152(1):19-26.

10. Das P, Moliterno DJ, Charnigo R, et al. Impact of drug-eluting stents on outcomes of patients with end-stage renal disease undergoing percutaneous coronary revascularization. J Invasive Cardiol. Sep 2006;18(9):405-408.

11. Khan MN, Joseph G, Khaykin Y, et al. Delayed lead perforation: a disturbing trend. Pacing Clin Electrophysiol. Mar 2005;28(3):251-253.

12. Tuzcu EM, Kapadia SR, Sachar R, et al. Intravascular ultrasound evidence of angiographically silent progression in coronary atherosclerosis predicts long-term morbidity and mortality after cardiac transplantation. J Am Coll Cardiol. May 3 2005;45(9):1538-1542.

13. Ziada KM, Yadav JS, Mukherjee D, et al. Comparison of results of carotid stenting followed by open heart surgery versus combined carotid endarterectomy and open heart

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surgery (coronary bypass with or without another procedure). Am J Cardiol. Aug 15 2005;96(4):519-523.

14. Chen MS, Bhatt DL, Mukherjee D, et al. Feasibility of simultaneous bilateral carotid artery stenting. Catheter Cardiovasc Interv. Apr 2004;61(4):437-442.

15. Wazni OM, Martin DO, Marrouche NF, et al. Plasma B-type natriuretic peptide levels predict postoperative atrial fibrillation in patients undergoing cardiac surgery. Circulation. Jul 13 2004;110(2):124-127.

16. Chiu JH, Bhatt DL, Ziada KM, et al. Impact of female sex on outcome after percutaneous coronary intervention. Am Heart J. Dec 2004;148(6):998-1002.

17. Cura FA, Kapadia SR, L'Allier PL, et al. Effect of uncoated stenting versus balloon angioplasty alone of long coronary (>20 mm) versus shorter narrowings on one-year event-free survival. Am J Cardiol. Mar 1 2003;91(5):587-590.

18. Tsutsui H, Schoenhagen P, Ziada KM, et al. Early constriction or expansion of the external elastic membrane area determines the late remodeling response and cumulative lumen loss in transplant vasculopathy: an intravascular ultrasound study with 4-year follow-up. J Heart Lung Transplant. May 2003;22(5):519-525.

19. Berkalp B, Badak O, Schoenhagen P, et al. Influence of various percutaneous coronary interventional devices on postinterventional luminal shape and plaque surface characteristics as determined by intravascular ultrasound. Am J Cardiol. May 15 2003;91(10):1269-1272.

20. Ramasubbu K, Schoenhagen P, Balghith MA, et al. Repeated intravascular ultrasound imaging in cardiac transplant recipients does not accelerate transplant coronary artery disease. J Am Coll Cardiol. May 21 2003;41(10):1739-1743.

21. Yadav JS, Ziada KM, Almany S, et al. Comparison of the QuickSeal Femoral Arterial Closure System with manual compression following diagnostic and interventional catheterization procedures. Am J Cardiol. Jun 15 2003;91(12):1463-1466, A1466.

22. Schoenhagen P, Stone GW, Nissen SE, et al. Coronary plaque morphology and frequency of ulceration distant from culprit lesions in patients with unstable and stable presentation. Arterioscler Thromb Vasc Biol. Oct 1 2003;23(10):1895-1900.

23. Casserly IP, Ziada K, Kapadia S, et al. Impact of nonmeasurable borders and variation in cross-section counts on intravascular ultrasound measurement of atherosclerotic plaque volume. Am J Cardiol. Jan 15 2002;89(2):169-173.

24. Jeremias A, Bhatt DL, Chew DP, et al. Safety of abciximab during percutaneous coronary intervention in patients with chronic renal insufficiency. Am J Cardiol. May 15 2002;89(10):1209-1211.

25. Schoenhagen P, Vince DG, Ziada KM, et al. Relation of matrix-metalloproteinase 3 found in coronary lesion samples retrieved by directional coronary atherectomy to intravascular ultrasound observations on coronary remodeling. Am J Cardiol. Jun 15 2002;89(12):1354-1359.

26. Jeremias A, Albirini A, Ziada KM, et al. Prognostic significance of creatine kinase-MB elevation after percutaneous coronary intervention in patients with chronic renal dysfunction. Am Heart J. Jun 2002;143(6):1040-1045.

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27. Iyisoy A, Schoenhagen P, Balghith M, et al. Remodeling pattern within diseased coronary segments as evidenced by intravascular ultrasound. Am J Cardiol. Sep 15 2002;90(6):636-638.

28. Iyisoy A, Ziada K, Schoenhagen P, et al. Intravascular ultrasound evidence of ostial narrowing in nonatherosclerotic left main coronary arteries. Am J Cardiol. Oct 1 2002;90(7):773-775.

29. Roffi M, Mukherjee D, Chew DP, et al. Lack of benefit from intravenous platelet glycoprotein IIb/IIIa receptor inhibition as adjunctive treatment for percutaneous interventions of aortocoronary bypass grafts: a pooled analysis of five randomized clinical trials. Circulation. Dec 10 2002;106(24):3063-3067.

30. Ziada KM, Roffi M, Yadav JS. Percutaneous stenting of a vertebral artery supplying the entire brain. Circulation. Mar 20 2001;103(11):E61.

31. Ziada KM, Kapadia SR, Belli G, et al. Prognostic value of absolute versus relative measures of the procedural result after successful coronary stenting: importance of vessel size in predicting long-term freedom from target vessel revascularization. Am Heart J. May 2001;141(5):823-831.

32. Mukherjee D, Roffi M, Kapadia SR, et al. Percutaneous intervention for symptomatic vertebral artery stenosis using coronary stents. J Invasive Cardiol. May 2001;13(5):363-366.

33. Ziada KM, Roffi M, Crowe TD, et al. Adventitial hematoma triggering coronary spasm during percutaneous coronary intervention. J Invasive Cardiol. Jun 2001;13(6):464-466.

34. Tuzcu EM, Kapadia SR, Tutar E, et al. High prevalence of coronary atherosclerosis in asymptomatic teenagers and young adults: evidence from intravascular ultrasound. Circulation. Jun 5 2001;103(22):2705-2710.

35. Kapadia SR, Nissen SE, Ziada KM, et al. Impact of lipid abnormalities in development and progression of transplant coronary disease: a serial intravascular ultrasound study. J Am Coll Cardiol. Jul 2001;38(1):206-213.

36. Tsutsui H, Ziada KM, Schoenhagen P, et al. Lumen loss in transplant coronary artery disease is a biphasic process involving early intimal thickening and late constrictive remodeling: results from a 5-year serial intravascular ultrasound study. Circulation. Aug 7 2001;104(6):653-657.

37. Schoenhagen P, Ziada KM, Vince DG, et al. Arterial remodeling and coronary artery disease: the concept of "dilated" versus "obstructive" coronary atherosclerosis. J Am Coll Cardiol. Aug 2001;38(2):297-306.

38. Kapadia SR, Bajzer CT, Ziada KM, et al. Initial experience of platelet glycoprotein IIb/IIIa inhibition with abciximab during carotid stenting: a safe and effective adjunctive therapy. Stroke. Oct 2001;32(10):2328-2332.

39. Schoenhagen P, Vince DG, Ziada KM, et al. Association of arterial expansion (expansive remodeling) of bifurcation lesions determined by intravascular ultrasonography with unstable clinical presentation. Am J Cardiol. Oct 1 2001;88(7):785-787.

40. Mukherjee D, Kalahasti V, Roffi M, et al. Self-expanding stents for carotid interventions: comparison of nitinol versus stainless-steel stents. J Invasive Cardiol. Nov 2001;13(11):732-735.

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41. Bhatt DL, Kapadia SR, Bajzer CT, et al. Dual antiplatelet therapy with clopidogrel and aspirin after carotid artery stenting. J Invasive Cardiol. Dec 2001;13(12):767-771.

42. Schoenhagen P, Ziada KM, Kapadia SR, et al. Extent and direction of arterial remodeling in stable versus unstable coronary syndromes: an intravascular ultrasound study. Circulation. Feb 15 2000;101(6):598-603.

43. Kapadia SR, Ziada KM, L'Allier PL, et al. Intravascular ultrasound imaging after cardiac transplantation: advantage of multi-vessel imaging. J Heart Lung Transplant. Feb 2000;19(2):167-172.

44. Cura FA, Bhatt DL, Lincoff AM, et al. Pronounced benefit of coronary stenting and adjunctive platelet glycoprotein IIb/IIIa inhibition in complex atherosclerotic lesions. Circulation. Jul 4 2000;102(1):28-34.

45. Ziada KM, Kapadia SR, Tuzcu EM, et al. The current status of intravascular ultrasound imaging. Curr Probl Cardiol. Sep 1999;24(9):541-566.

46. Ziada KM, Tuzcu EM, Nissen SE. Application of intravascular ultrasound imaging in understanding and guiding percutaneous therapy for atherosclerotic coronary disease. Cardiol Rev. Sep-Oct 1999;7(5):289-300.

47. Kapadia SR, Nissen SE, Ziada KM, et al. Development of transplantation vasculopathy and progression of donor-transmitted atherosclerosis: comparison by serial intravascular ultrasound imaging. Circulation. Dec 15 1998;98(24):2672-2678.

48. Ziada KM, Tuzcu EM, De Franco AC, et al. Intravascular ultrasound assessment of the prevalence and causes of angiographic "haziness" following high-pressure coronary stenting. Am J Cardiol. Jul 15 1997;80(2):116-121.

Book Chapters

1. De Franco AC, Tuzcu EM, Ziada KM, Nissen SE. Intravascular ultrasound assessment of PTCA results: mechanisms and clinical implications. In: Siegel RJ, editor. Intravascular ultrasound imaging in coronary artery disease. Marcel Dekker, Inc., New York, NY. 1998; 205-43.

2. Nissen SE, Ziada KM, Tuzcu EM. Detection of atherosclerosis and identification of vulnerable plaque: potential role of intravascular ultrasound. In: Fuster V, editor. The vulnerable atherosclerotic plaque: understanding, identification, and modification. Futura Publishing Co., Armonk, NY 1999; 87-109.

3. De Franco AC, Safian RD, Ziada KM, Tuzcu EM, Nissen SE. Intravascular ultrasound. In: Safian RD, Freed MS, editors. The Manual of Interventional Cardiology. Physicians’ Press, Royal Oak, MI. 2001; 693-733.

4. Ziada KM, Bhatt DL. Evaluation of coronary lesions of intermediate severity. In: Deepak L Bhatt, editor. Essential Concepts of Cardiovascualar Intervention. Remdica Publishing, 2003.

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5. Ziada KM, Roffi M. Chest pain with normal coronary arteries. In Marco Roffi, Bernard Meier, Marco Roffi, editors. CMVstat: A Handheld Computer-Based Approach to CardioVascular Medicine (an e-book).

6. Ziada KM, Olin J. Non-invasive evaluation of Arterial Disease. In: Yadav JS, Casserly IP, Sachar R, editors. Manual of Peripheral Vascular Intervention. Lippincott, Williams and Wilkins. Philadelphia, PA 2005; pp8-35.

7. Hamdalla H, Ziada K. Intravascular Ultrasound. In “900 Questions An Interventional Cardiology Board Review.” Moliterno DJ, Mukherjee D, Cho L eds. 1st edition. Lippincott, Williams and Wilkins. Philadelphia, PA 2007; pp 192-201.

8. Ziada KM, Mukherjee D. Periprocedural myocardial infarction and embolism protection devices. In “Textbook of Interventional Cardiology” 5th edition. Topol EJ editor. Saunders Elsevier. Philadelphia, PA, 2008; pp 491-512.

9. Ziada KM. Upper extremity and vertebral angiography and angioplasty. In “Cardiac catheterization and interventional cardiology self-assessment program 3”. Moliterno DL editor. Published by the American College of Cardiology Foundation, 2008.

10. Ziada KM and Nissen SE. intrvascular ultrasound Imaging. In “Cardiac catheterization and interventional cardiology self-assessment program 3”. Moliterno DL editor. Published by the American College of Cardiology Foundation, 2008.

11. Bilkoo P and Ziada K. Management of stent thrombosis and in-stent restenosis. In “Diagnostic Methods in the Catheterization Laboratory”. Lemos, Schoenhagen and Lansky editors. In press.

12. Hammock J, Steinhubl S and Ziada KM. Anti-platelet Therapy. In “Cardiac Intensive Care, 2nd Edition. Jeremias A and Brown DL, editors. In press

Selected Abstracts:

1. Ziada KM, Tuzcu EM, De Franco AC, et al. Angiographic “haziness” following stent deployment: Differential diagnosis using intravascular ultrasound. J Am Coll Cardiol 1996; 2 (27): 224A.

2. De Franco AC, Tuzcu EM, Ziada KM, et al. High-pressure inflations do not insure “adequate” stent deployment: evidence from intravascular ultrasound. J Am Coll Cardiol 1996; 2 (27): 305A.

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3. Ziada KM, Tuzcu EM, De Franco AC, et al. Absolute, not relative, post-stent lumen area is a better predictor of clinical events. Circulation 1996; 94 (8): I-453.

4. Ziada KM, Tuzcu EM, De Franco AC, et al. Does shape of in-stent lumen affect outcome? An intravascular ultrasound analysis. Circulation 1996; 94 (8): I-199.

5. Kim MH, Ziada KM, Crowe TD, et al. Intravascular ultrasound assessment of coronary artery ‘tapering’. Circulation 1996; 94 (8): I-134.

6. Crowe TD, Kim MH, Ziada KM, et al. Reproducibility and sources of variability in intravascular ultrasound imaging. Circulation 1996; 94 (8): I-654.

7. Feldman T, Bersin RM, Levin TN, Magyar WA, Raymond RE, Ziada KM, Nissen SE, Whitlow PL. IVUS results of the STRATAS Trial: vessel dimensions after ‘conventional’ versus ‘stepped-burr’ rotational atherectomy. Circulation 1996; 94 (8): I-317.

8. Ziada KM, Kim MH, Potts W, et al. Predictors of target vessel revascularization following coronary stent deployment. J Am Coll Cardiol 1997; 29 (2): 239A.

9. Kim MH, Ziada KM, De Franco AC, et al. “Step-up” or “step-down” in small stented vessels does not adversely impact clinical outcome. J Am Coll Cardiol 1997; 29 (2): 279A.

10. Kim MH, Nissen SE, Crowe T, Ziada KM, Hobbs RE, Young JB, Tuzcu EM. Time course and magnitude of vascular remodeling in early and advanced coronary atherosclerosis. J Am Coll Cardiol 1997; 29 (2): 178A.

11. Ziada KM, Kapadia SR, Crowe TD, Binak E, Motwani JG, YoungJB, Nissen SE, Tuzcu EM. Three-year ultrasound follow-up of donor transmitted coronary atherosclerosis in transplant recipients. Circulation 1997; 96 (8): I-65.

12. Kapadia SR, Crowe TD, Ziada KM, Kim MH, Guetta V, Hobbs RE, Young JB, Nissen SE, Tuzcu EM. Hypertriglyceridemia is a risk factor for progression of donor transmitted atherosclerosis after heart transplantation. Circulation 1997; 96 (8): I-413.

13. Crowe TD, Magyar WA, Ziada KM, Guetta V, Nissen SE, Tuzcu EM. Reproducibility of site matching and measurements in serial intravascular ultrasound studies. Circulation 1997; 96 (8): I-587.

14. Ziada KM, Kapadia SR, Crowe TD, Rincon G, Goormastic M, Guetta V, Nissen SE, Tuzcu EM. Serial intravascular ultrasound evaluation of remodeling in transplant coronary disease: influence of disease progression. J Am Coll Cardiol 1998; 31: 91A

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15. Kapadia SR, Ziada KM, Crowe TD, Young JB, Starling RC, Silver MJ, Nissen SE, Tuzcu EM. Development and progression of transplant vasculopathy: serial intravascular ultrasound study. J Am Coll Cardiol 1998; 31: 2A

16. Kapadia SR, Ziada KM, Platt L, Boparai N, Starling RE, Nissen SE, Tuzcu EM. Donor disease does not predict clinical outcome in patients surviving first year after transplantation. Circulation 1998; 17: I-546.

17. Kapadia SR, Ziada KM, Boparai N, Platt L, Ozduran V, Crowe TD, Young JB, Hobbs RE, Nissen SE, Tuzcu EM. Coronary artery intimal thickening during the first year of cardiac transplantation predicts late clinical outcome: a serial intravascular ultrasound study. J Am Coll Cardiol 1999; 33: 218A.

18. Kapadia SR, Ziada KM, Ozduran V, Magyar WA, Young JB, Starling RE, Nissen SE, Tuzcu EM. Does single vessel intravascular ultrasound imaging adequately reflect the prevalence and severity of transplant vasculopathy? J Am Coll Cardiol 1999; 33: 68A..

19. Ziada KM, Kapadia SR, Crowe TD, Steinhubl SR, Horner S, Nissen SE, Tuzcu EM. Remodeling does not prevent lumen loss in early stages of transplant vasculopathy: a serial intravascular ultrasound study. J Am Coll Cardiol 1999; 33: 218A.

20. Ziada KM, Kapadia SR, Crowe TD, Bajzer CT, Rodkey SM, Ozduran V, Nissen SE, Tuzcu EM. Adaptive coronary remodeling is evident in later stages of transplant vasculopathy: a serial intravascular ultrasound study. J Am Coll Cardiol 1999; 33: 90A.

21. Ziada KM, Kapadia SR, Goormastic M, Ertas FS, Crowe TD, Gustavo Rincon, Nissen SE, Tuzcu EM. Impact of Remodeling on Coronary Lumen Loss in Transplant Vasculopathy: A Serial Intravascular Ultrasound Study. J Am Coll Cardiol 2000; 35(2): 239A.

22. Ziada KM, Kapadia SR, Belli G, Houghtaling PL, Whitlow PL, Franco I, Ellis SG, Nissen SE, Tuzcu EM. Impact of The Vessel Size And Procedural Result on The Long Term Outcome Following Coronary Stenting. J Am Coll Cardiol 2000; 35(2): 17A.

23. Ziada KM, Amrik Shah, Kapadia SR, Crowe TD, Rai M, Casserly I, Nissen SE, Tuzcu EM. Intravascular Ultrasound Measurement of Plaque Volume: Validation of a Method for Serial Regression-Progression Studies. J Am Coll Cardiol 2000; 35(2): 47A.

24. Kapadia SR, Ziada KM, Wazni OM, Tutar E, Rai M, Casserly I, Lutton SR, Nissen SE, Tuzcu EM. Normal Intimal Thickness is an Age Dependent Phenomenon: An Intravascular Ultrasound Study in Asymptomatic Individuals J Am Coll Cardiol 2000; 35(2): 94A.

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K.M. Ziada, M.D. curriculum vitae

25. Ziada KM, Kapadia SR, Bhatt DL, et al. Approach to Carotid Stenosis in Patients Undergoing Open Heart Surgery: Stenting or Endarterectomy? J Am Coll Cardiol 2001; 37 (2): 39A.

26. Jeremias A, Albirini A, Ziada KM, et al. Creatine Kinase-MB Elevation After Percutaneous Coronary Intervention is a Predictor of Long-Term Mortality in Patients With Renal Dysfunction. J Am Coll Cardiol 2001; 37 (2): 75A.

27. Roffi M, Häfeli UO, Ziada KM, Kapadia SR, Ciezki JP. Delayed Healing of the Vessel Wall Persists at 6 Months Following Endovascular Radiation. J Am Coll Cardiol 2001; 37 (2): 55A.

28. Sachar R, Kapadia SR, Ziada KM, et al. Intimal Thickness One Year After Cardiac Transplantation Is a Strong Predictor of Long Term Clinical Outcome: A Serial Intravascular Ultrasound Study. J Am Coll Cardiol 2001; 37 (2): 182A

29. Ellis K, Ziada KM, Vivekanathan D, et al. The negative predictive value of transthoracic echocardiography for left atrial appendage thrombus. Circulation 2003; 108 (17): IV-482.

30. Ziada KM, Yadav JS, Lauer MS, et al. Improved outcomes with carotid stenting prior to open heart surgery compared to combined carotid endarterectomy and open heart surgery. Circulation 2003; 108 (17): IV-632.

31. Das P, Moliterno DJ, Sneed D, Charnigo R, Mukherjee D, Steinhubl SR, Booth DC, Ziada KM. Impact of drug-eluting stents on outcomes of patients with end-stage renal disease undergoing percutaneous coronary revascularization. J Am Coll Cardiol 2006; 47 (4): 28B.

32. Gurm HS, Breitbart Y, Vivekanathan D, Yen MH, Fathi R, Ziada KM, Whitlow PL, Ellis SG. Preprocedural statin use is associated with a reduced hazard of postprocedural myonecrosis in patients undergoing rotational atherectomy—a propensity-adjusted analysis. Am Heart J. 2006 May;151(5):1038.e-1-6.

33. Das P, Ziada K, Hanna E, Falluji N, Booth D, Moliterno D, Mukherjee D. Do octogenarians benefit from drug-eluting stents? Am J Cardiol 2006; 171M.

34. Bhatheja, R, Mukherjee, D, Minion, Da., Sorial, E, Dhaliwal, G, Charnigo, R, Ziada, K. Long Term Major Adverse Cardiac and Vascular Evantas Following Renal Artery Stenting. The American Journal of Cardiology 2007;202L.

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K.M. Ziada, M.D. curriculum vitae

Honors and Awards

Graduated with honors from School of Medicine, Cairo University (top 1% of students throughout his school years)

Recognized by the Egyptian Hypertension League as a founding member and for organizing the 1st scientific meeting for the League members held in 1994.

Recognized by the National Hypertension Project of Egypt, a collaborative effort between Cairo University, Egyptian Ministry of Health, Johns Hopkins Medical School, and the NHLBI

Clinical Research Award 2003, Cleveland Clinic Cardiovascular Department (paper on carotid stenting in patients undergoing open heart surgery)

Finalist, Astra-Zeneca Cardiovascular Forum Young Investigator Award, 2003 (same paper on carotid stenting in patients undergoing open heart surgery)

Professional Society Memberships

Fellow, American College of Cardiology (since 1998), Fellow of the College since 2006 Member, American Collage of Physicians (since 2001) Member, American Heart Association – Council on Clinical Cardiology (since 2003) Member, Society of Cardiac Angiography and Interventions (since 2005), Fellow of the

Society since 2006 Founding member, the Egyptian Hypertension League (since 1994) Member, the Egyptian Society of Cardiology (since 1993)

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