Curriculum Vitae

Name: Pawel S. Ciborowski

Campus Address:Department of Pharmacology and Experimental NeuroscienceUniversity of Nebraska Medical Center985800 Nebraska Medical CenterOmaha, NE, 68198-5800

Place of Birth: Warszawa, Poland

Education:1977 Master of Science, Biochemistry, University of Warsaw, Warsaw, Poland.1983 Doctor of Philosophy, Biochemistry and Bacteriology, National Institute of Hygiene, Warsaw, Poland.

Post-Degree Training:

1984-1986 Alexander von Humboldt Foundation Fellow, Institute of Hygiene, University of Cologne, Cologne, Germany.

Academic Appointments:

2014 - present Professor with tenure, Department of Pharmacology and Experimental Neuroscience (primary) and Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE

2012-2014 Associate Professor with tenure, Department of Pharmacology and Experimental Neuroscience (primary), Department of Biochemistry and Molecular Biology, and Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE

2009-2014 Associate Professor, Department of Pharmacology and Experimental Neuroscience (primary), Department of Biochemistry and Molecular Biology, and Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE

2006-2017 Director, Mass Spectrometry and Proteomics Core Facility, University of Nebraska Medical Center, Omaha, NE

2004-2009 Assistant Professor, Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, primary since 2007.

2004-2009 Assistant Professor, Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE

2003-present Director of Proteomics Program, Center for Neurovirology and Neurodegenerative Disorders, University of Nebraska Medical Center, Omaha, NE, primary until 2007.

2003-2009 Assistant Professor, Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE

2001-2003 Senior Staff Scientist, GlycoTech Corp., Rockville, MD1998-2001 Research Instructor, School of Medicine, Department of Molecular Genetics & Biochemistry,

University of Pittsburgh, Pittsburgh, PA1997-1998 Core Facility Manager, Protein Chemistry, Department of Molecular Genetics & Biochemistry,

University of Pittsburgh, Pittsburgh, PA.1994- 1998 Senior Research Associate, School of Medicine, Department of Molecular Genetics &

Biochemistry, University of Pittsburgh, Pittsburgh, PA1991-1994 Research Associate, University of Pittsburgh, School of Dental Medicine, Pittsburgh, PA1989-1990 Visiting Scientist, Institute for Medical Microbiology University of Lund, Lund, Sweden1986-1989 Assistant Professor, Department of Bacteriology, National Institute of Hygiene, Warsaw, Poland

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Continuing Education

1995 Good Manufacturing Practice Course (3 days), GMP Institute Good Laboratory Practice, University of Pittsburgh, Pittsburgh, PA.

1995 Course in mass spectrometric analysis of glycoconjugates (1 week), Complex Carbohydrate Research Center, University of Georgia, Athens, GA.

Grant and Contract Support:

Active:1. 1 R01 DA043258-01, “Macrophage, Meth, HIV and Histones: An Interplay” (DHHS/NIH/NIDA, $624,647),

Multiple PIs: P. Ciborowski (contact) and H.Fox, 09/1/16-06/30/21, 40% effort. 2. 5 P30 MH062261-12, "Chronic HIV Infection and Ageing in NeuroAIDS (CHAIN) Center" (Fox/Buch)

(DHHS/NIH/NIMH, $1,371,907), P.I. H. Fox, Phenomics Core, Core Director:  P. Ciborowski 03/01/2011 – 02/29/2016, 20% effort.

3. University of Nebraska Collaboration Initiative Seed Grant “Dynamical Modeling as a Method for Integrating Multi-Level Data for Translational Science in Innate Immunity” P.I. J Rogers, Co-I P. Ciborowski. Duration 07/01/2017 to 06/30/2019. Total amount $ 161,154.00 (no faculty salary allowed).

Pending:

1. 1 R21 AI135931-01 “Role of placenta macrophages in mother to child transmission of Zika virus” P.I. L. Melendez, Sub-contract P. Ciborowski.

Past:

1. 5R01DA030962-02, “Transcriptional regulation, the nuclear proteome, and HIV/Meth/cART: From profiling to biological function” (DHHS/NIH/NIDA, $500,000), Multiple PIs: H.Fox and P.Ciborowski, 09/17/10-09/16/15, 15% effort.

2. 5 P30 MH062261-12, "Chronic HIV Infection and Ageing in NeuroAIDS (CHAIN) Center" (Fox) (DHHS/NIH/NIMH, $1,371,907), P.I. H. Fox, Phenomics Core, Core Director: P. Ciborowski 03/01/2011 – 02/29/2016, 6% effort.

3. 5R01DA030962-02, “Transcriptional regulation, the nuclear proteome, and HIV/Meth/cART: From profiling to biological function” (DHHS/NIH/NIDA, $500,000), Multiple PIs: H.Fox and P.Ciborowski, 09/17/10-09/16/15, 15% effort.

4. 5 P30 MH062261-12, "Chronic HIV Infection and Ageing in NeuroAIDS (CHAIN) Center" (Fox) (DHHS/NIH/NIMH, $1,371,907), P.I. H. Fox, Phenomics Core, Core Director: P. Ciborowski 03/01/2011 – 02/29/2016, 6% effort.

5. 1R01AI080348-01, “A Proteomic and Biochemical Study of HIV-1 Nucleoprotein Complexes” (DHHD/NIH/NIAID, $40,000), PI: M. Belshan, Subcontract, P.I: P. Ciborowski, (05/01/2010 – 04/30/2015), 3% effort.

6. R01 NS063878 “Macrophages, NR2B-containing NMDA receptors and HIV dementia” (DHHS/NIH/NINDS, $250,000), PI: H. Xiong, Co-I: P. Ciborowski, 02/01/09–01/31/14, 5% effort.

7. P20RR16469, “Nebraska Research Network in Functional Genomics”, (DHHS/NIH/NCRR) PI: J.B. Turpen, Mass Spectrometry and Proteomics Core Director: P. Ciborowski, (05/01/2009-04/30/2014), 10% effort.

8. 1 R01 MH081780-01A1, “Blood Brain Barrier Immune Compromise in NeuroAID” (DHHS/NIH/NIMH, $250,000), PI: G. Kanmogne, Co-I: P. Ciborowski, 4/1/08-3/31/13, 3% effort.

9. 1 R01 NS061642-01A1, “SDF-1 and Neurogenesis in HIV-1 Associated Dementia” (DHHS/NIH/NINDS, $250,000), PI: J. Zheng, Co-I: P. Ciborowski, 12/01/08–11/30/11, 5% effort.

10. 2 P01NS043985-06A1, “Neural Immunity in HIV Dementia” (DHHS/NIH/NINDS, $800,000), PI: H.E. Gendelman, Core C: Proteomics Core, Core C Leader: P. Ciborowski, 3/1/09-2/28/13, 15% effort.

11. 2 R01 NS034239-13A1, “Neuroprotective Immunity and HIV Dementia” (DHHS/NIH/NINDS, $250,000) PI: H.E. Gendelman, Co-I: P. Ciborowski, 7/1/08-6/30/12, 10% effort.

12. 1 P20DA026146-01, “Proteomic Strategies for AIDS and Drug Abuse – HIV and METH CNS Synergy” (DHHS/NIH/NIDA, $700,000), PI: H. Fox, Project 3 P.I.: P.Ciborowski, 10/1/08-9/30/11.

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13. 5 R01 HL085061-02, “Role of Ryanodine Receptor in Diabetic Cardiomyopathy“(DHHS/NIH/NHLBI, $250,000), PI: K. Bidasee, Co-I: P. Ciborowski, 02/01/08–1/31/11.

14. 1 R21 MH075662-01, “Macrophage Protein Fingerprints in HIV-1 Dementia” (DHHS/NIH/NIMH, $150,000), P.I.: P. Ciborowski, 08/01/2005 – 07/31/2007.

15. P20 RR 15635-02, “Cellular Mechanisms for HIV-1 Induced Neuronal Injury” (DHHS/NIH/NCRR, $200,000), PI: C. Wood (COBRE and NCV Center Director), Project leader: P. Ciborowski, 09/01/2003-06/30/2005.

16. U54 NS43011-07, “Immunopathogenesis of HIV Neurological Disorders: Project 2: Monocyte Immunity and HIV-1 Induced Dementia” (DHHS/NIH/NINDS to University of Puerto Rico, $85,000), PI: H.E. Gendelman, Co-I: P. Ciborowski, 9/29/06-8/31/08.

17. 1F33CA073214-01A1, “Breast cancer MUC-1 in cell adhesion and metastasis” (DHHD/NIH/NCI, $32,000), P.I.: P. Ciborowski, (02/03/1998 – 01/31/2000), 100% effort (senior post-doctoral fellowship).

Other activities involving service or scholarly activity:

National and International Review Panels:

1. ZDA1 SXM-M (09) R Mechanisms of Immune Activation and Inflammation: HIV Infection, ART, and Drugs of Abuse (R01), reviewer, 2017

2. “NIDA’s Avenir Award Program for Genetics or Epigenetics of Substance Use Disorders” Phase I reviewer, 2017

3. Deutsche Forschungsgemeinschaft (DFG), Individual grant review – mail in, ad hock reviewer, 2016 4. ZDE1 LC (10), NIH, “Oral Immune System Plasticity in Chronic HIV Infection Under Treatment and Oral

co-infections” reviewer, 20165. ZAI PA-I (S1) 1 NIH, “Human Immunology Project Consortium (U19)” reviewer, 20166. ZRG1 F04B-D (20) L fellowship review panel, reviewer, 20167. ZRG1 AARR-K (58), NIH, Multidisciplinary Studies of HIV/AIDS and Aging, reviewer, 20158. ZDE1 CF (10), NIH/NIDCR Oral HIV Reservoirs (RO1), reviewer, 20159. Polish Science Council, ad hock grant reviewer, 201510. ZRG1 F04B-D (20), NIH, F04B fellowship review panel, reviewer, 201511. ZRG1 AARR-C 04, NIH, Special Emphasis Panel for NAED Study Section, reviewer, 201512. ZDA1 NXR-B-03, NIH, P30 center grants review panel, reviewer, 201513. ZDA1 NXR-B-04, NIH, P50 center grants review panel, reviewer, 201514. ZAI1 LGR-I(M1), NIH, Human Immunology Project Consortium (U19)” reviewer, 201515. ZRG1 F04B-D (20), NIH, F04B fellowship review panel, reviewer, 201416. ZRG1 BST A 50 R, NIH, Exceptionally Innovative tools and Technologies for Single Cell Analysis and

Validation and Advanced Development of Technologies for the Study of Biological Properties of Single Cells, reviewer, 2014

17. ZAI1-ZL-I (J1), NIH, Immune Mechanisms of Virus Control (U19), reviewer, 2013 18. ZRG1 BST-N(40), NIH, Proteomics Research Center for Integrative Biology (P41), Battelle National

Laboratories, reviewer with site visit, 201319. ZRG1 CB D51 R, NIH, Exceptionally Innovative Tools and Technologies for Single Cell Analysis

(R21), reviewer, 201220. ZRG1 BCMB-D Mass Spectrometry Shared Instruments NIH/NCRR study section, reviewer, 200921. Health Research Board Clinician Scientists Award, Ireland22. Member of International Scientific Review Panel for Polish Leading National Scientific Centers (LNSC)

Program, Ministry of Science and Higher Education of the Republic of Poland.23. Division of Molecular and Cellular Biosciences, National Science Foundation, 201124. UNMC Graduate Student Fellowship Reviewer, 2008, 2009, 2010, 2011, 2012, 201325. Ad hoc grant reviewer for the Department of the Army, US Army Research, 2004 and 200726. Ad hoc grant reviewer for University of Puerto Rico Medical Sciences Campus, Minority Biomedical

Research Support Program (MBRS), Support of Competitive Research (SCORE), 200727. Ad hoc grant reviewer for National Health Laboratory Services Research Trust Grants, Republic of

South Africa, 2007 and 200828. Ad hoc grant reviewer for Kentucky Science & Engineering Foundation, 200629. Ad hoc grant reviewer for Veterans Administration, Office of External Reviews, 200630. Ad hoc grant reviewer for the Veterans Administration, Office of External Reviews, 2001

Consulting (corporate and academic):

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1. Consultant on NIH grant, P.I. Patrick Swanson, Creighton University, Omaha, NE2. Transgenomic, Inc. Omaha, NE3. Proventa International, Inc. London, UK

Peer-review services:1. Editorial Boards:

a. International Journal of Clinical and Experimental Medicine – member since 2011b. International Journal of Analytical Chemistry – member since 2012

2. Multiple reviews:a. Journal of Proteome Research (2006 - present)b. Proteome Science (2008, 2009, 2010, 2014)c. Proteomics (2007, 2008, 2009, 2010, 2011)d. PLoSOne (2009, 2010, 2011, 2013)e. Expert Review in Proteomics (2013, 2014, 2015)f. Journal of Neuroimmune Pharmacology (2008, 2009)g. Libertas Academica (2008, 2009, 2010, 2011, 2013, 2014)h. Medical Science Monitor (2008, 2010, 2011)

3. Ad hoc reviewer: a. Nature Methods (2014)b. Nature Protocols (2015)c. Molecular and Cellular Proteomicsd. Journal of Proteomicse. Molecular and Cellular Biochemistryf. Analytical Chemistryg. Biochemistryh. Advances in Medical Sciencesi. Neuroplasia (2015)j. Nanomedicine (2015)k. Journal of Separation Sciencel. Spectrochimica Acta Part Am. Neurochemistry Internationaln. European Journal of Neurologyo. Biomedical Chromatographyp. Medical Chemistry Reviewsq. Analytical Chemistry Insightsr. Acta Biochemica and Biophysica Sinica (2014)s. Indian Journal of Virologyt. The Open Virology Journalu. Drug Discovery Todayv. BoldFace Editors, Inc.w. Cancer Immunology Immunotherapyx. Cancer Researchy. Clinical Cancer Researchz. Clinical and Diagnostic Laboratory Immunologyaa. European Journal of Cancerbb. Molecular Biology Reportscc. Tumor Biology

4. Guest Associate Editor of “Cellular Immunity and Immunotherapy of Cancer”, Supplement to Clinical Cancer Research, 2001, 7(3 Suppl).

Honors and Awards:1. Distinguished Scientist, University of Nebraska Medical Center, 20122. University of Pittsburgh Cancer Institute, Scientific Retreat, Poster Competition, Third Place. – 19953. European Society for Clinical Microbiology and Infectious Diseases Travel Grant Awards, for the 70 th

International Association for Dental Research General Session, Glasgow, Scotland. – July, 1-4, 19924. European Society for Clinical Microbiology and Infectious Diseases Travel Grant Awards, for the 6th

Mediterranean Congress of Chemotherapy, Taormina-Giardini Naxos, Italy. – May 22-27,1988

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5. Upjohn Co. Travel Grant Award, the Third European Congress of Clinical Microbiology, The Hague, The Netherlands. - 1986

6. Post-doctoral fellowship from Alexander von Humboldt Foundation. – 19847. Group award of the President of the University of Warsaw for an outstanding completion of research project -

diploma work for M.S. degree was a part of this project.- 19838. Award of the Chairman of Scientific Advisory Council of Department of Health and Social Welfare for an

outstanding Ph.D. thesis. - 1983

Professional Societies:1. American Society for Mass Spectrometry (ASMS)2. Association of Biomolecular Resource Facilities (ABRF)3. Society for Neuroscience (SfN)4. US Human Proteome Organization (USHUPO)5. World Human Proteome Organization (HUPO)6. American Society for Biochemistry and Molecular Biology (ASBMB)7. American Chemical Society (ACS)8. International Society for NeuroVirology (ISNV)9. Society for Nauroimmune Pharmacology (SNIP)

Committee Assignments:1. INBRE Steering Committee, UNMC – member (2007 – 2014).2. Protein Structure Core Facility Internal Advisory Committee – member (2003 – 2010).3. Biochemistry and Molecular Biology Faculty Search Committee, UNMC (2004-2007).

Bibliography:Articles in Scholarly Journals:

1. P. Ciborowski, B. Wilkomirski, W. Zdrojewski and Z .Kasprzyk. Biosynthesis of oleanolic acid glycosides in Calendula officicnalis inflorescens. Phytochemistry 1983, 22:107-110.

2. S. Tyski, P. Ciborowski, W. Hryniewicz and J. Jeljaszewicz. Lipolytic and proteolytic character of staphylococcal human isolates. Zbl. Bakt. Hyg. I Abt. Orig.A, 1983, 745:452-458.

3. P.Ciborowski. Isolation and purification of Clostridium butyricum M 55 proteolytic enzymes. Experimental Medicine and Microbiology (Polish) 1983, 35:199-213.

4. S. Tyski, W. Hryniewicz and P. Ciborowski. Determination of lipolytic properties of human Staphylococcal strains. Experimental Medicine and Microbiology (Polish) 1983, 35:9-14.

5. P. Ciborowski, S. Tyski and W. Hryniewicz. Production of proteolytic enzymes by Staphylococci isolated from human infections. Experimental Medicine and Microbiology (Polish) 1983, 35:15-20.

6. J. Jeljaszewicz, P. Ciborowski, L.M. Switalski, S. Tyski and E. Zajdel. Extracellular enzymes. In: Staphylokokken und Staphylokokkenerkrankungen bei Mensch und Tier. (W. Mayer ed.) 1984, Gustav Fisher Verlag, Jena, pp. 105-130.

7. S. Tylewska, S. Tyski, W. Hryniewicz, P. Ciborowski and J. Jeljaszewicz. Effect of staphylococcal lipase on chemotactic activity of human neutrophils. In: The Staphylococci. Proceedings of the V-th International Symposium on Staphylococci and Staphylococcal Infections. (J.Jeljaszewicz ed.) Zbl. Bakt. Hyg. Suppl 14, 1985, Gustav Fisher Verlag, Stuttgart, New York, pp. 311-313.

8. W. Roszkowski, P. Ciborowski, H.L. Ko, F. Schumacher-Perdreau, K. Roszkowski, J. Jeljaszewicz and G. Pulverer. The effects of subinhibitory concentration of selected antibiotics on bacteria-phagocyte interaction. In: The influence of antibiotics on the host-parasite relationships II. (H.V.Eickenberg, H.Hahn and W.Opferkuch eds.), 1986, Springer Verlag, Berlin, Heidelberg, New York, pp. 98-112.

9. A. Przondo-Hessek, H. L. Ko, P. Ciborowski, W. Roszkowski and G. Pulverer. Interaction of Klebsiella strains with human polymorphonuclear leucocytes. Zbl. Bakt. Mikrobiol. Hyg. I Abt. Orig. A., 1986, 262:522-530.

10. W. Roszkowski, H.L. Ko, K. Roszkowski, P. Ciborowski, J. Jeljaszewicz and G. Pulverer. Effect of ciprofloxacin on the humoral and cellular immune response in Balb/c-mice. Zbl. Bakt. Hyg. I Abt. Orig. A, 1986, 262:396-402.

11. M. Tashiro, P. Ciborowski, H-D. Klenk, G. Pulverer and R. Rott. Role of staphylococcal protease in development of influenza pneumonia. Nature 1987, 325:536-537.

12. M. Tashiro, P. Ciborowski, M. Reinacher, G. Pulverer, H-D. Klenk and R. Rott. Synergistic role of staphylococcal proteases in the induction of influenza virus pathogenicity. Virology 1987, 157:421-427.

13. P. Ciborowski, W. Hryniewicz and J. Jeljaszewicz. Purification and partial characterization of two proteinases from Clostridium butyricum M 55. Zbl. Bakt. Hyg. I Abt. Orig. A, 1988, 268:180-192.

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14. J. Miedzobrodzki, A.S. Naidu, J.L. Watts, P. Ciborowski, K. Palm and T. Wadstrom. Effect of milk on fibronectin and collagen type I binding to Staphylococcus aureus and coagulase-negative staphylococci isolated from bovine mastitis. J. Clin. Microbiol. 1989, 27:540-544.

15. W. Roszkowski, B. Wesolowska, H.L. Ko, K. Roszkowski, P. Ciborowski, J. Jeljaszewicz and G. Pulverer. Influence of mezlocillin administration to pregnant mice on the immune system of their offspring. In: The Influence of Antibiotics on the Host-Parasite Relationship III. (G. Gillisen, W. Opferkuch, G. Peters and G. Pulverer, eds.) 1989, Springer-Verlag, Berlin, Heidelberg, pp. 231-236.

16. P. Garlinski, S. Tyski, P. Ciborowski, W Roszkowski and J.Jeljaszewicz. Influence of staphylococcal lipase on chemiluminescence of human granulocytes. In: The Staphylococci Proceedings of the VI-th International Symposium on Staphylococci and Staphylococcal Infections. (J. Jeljaszewicz and P. Ciborowski, eds.) Zbl. Bakt. Hyg. Suppl 21, 1991, Gustav Fisher Verlag, Stuttgart, New York, pp.317-318.

17. P. Ciborowski, J-I. Flock and T. Wadstrom. Immunological response to staphylococcal fibronectin binding protein. J. Med. Microbiol. 1992, 37:376-381

18. M.S. Lantz, R.D. Allen, P. Ciborowski, and S.C. Holt. Purification and immunolocalization of a cysteine protease from Porphyromonas gingivalis. J. Periodont. Res. 1993, 28:467-469.

19. M.S. Lantz and P. Ciborowski. Zymographic techniques for detection and characterization of microbial proteases. In: Methods in Enzymology. (V.L. Clark and P.M. Bavoil eds.) 1994, Academic Press, San Diego, New York, Boston, London, Sydney, Tokyo and Toronto, pp.563-594.

20. P. Ciborowski, M. Nishikata, R.D. Allen, and M.S. Lantz. Purification and characterization of two form of a high molecular weight cysteine proteases (porphypain) from Porphyromonas gingivalis. J. Bact. 1994, 176:4549-4557.

21. P. Ciborowski and O.J. Finn. Recombinant epithelial cell mucin (MUC-1) expressed in baculovirus resembles antigenically tumor associated mucin, target for cancer immunotherapy. Biomedical Peptides, Proteins and Nucleic Acids 1995, 1:193-198.

22. P. Ciborowski, W.M. Konitzki, J. Magarian-Blander, and O.J. Finn. Screening of the workshop anti-MUC-1 antibodies for reactivity with native (ascites) and recombinant (baculovirus) MUC-1 and for blocking MUC-1-specific CTL. Tumor Biology 1998, 19(suppl. 1):147-151.

23. J. Magarian-Blander, P. Ciborowski, S. Watkins, S. Hsia, and O.J. Finn. Intercellular and intracellular events following the MHC-unrestricted TCR recognition of a tumor-specific peptide epitope on the epithelial antigen MUC1. J. Immunol. 1998, 160:3111-3120.

24. E. M. Hiltbold, P. Ciborowski, and O.J. Finn. Naturally processed class II epitope from the tumor antigen MUC1 primes human CD+T cells. Cancer Research 1998, 58:5066-5070.

25. P. Ciborowski, E. M. Hiltbold, S.M. Barrat-Boyes, and O.J. Finn. MUC1 Mucin as a Tumor Antigen in Breast Cancer. In: Breast Cancer: Molecular Genetisc, Pathogenesis, and Therapeutics (A. M. Bowcock ed.) 1998, Humana Press Inc., Totowa, NJ, pp. 453-468.

26. E. M. Hiltbold, M. D. Alter, P. Ciborowski and O. J. Finn. Presentation of MUC1 tumor antigen by class I MHC and CTL function correlate with the glycosylation state of the protein taken up by dendritic cells. Cellular Immunology 1999, 194:143-149.

27. P. Ciborowski and O.J.Finn. Expression of MUC-1 mucin in insect cells using baculovirus vectors. In: Glycoproteins Methods and Protocols, The Mucins; Methods in Molecular Biology, v. 125, (Tony Corfield ed.) 2000, Humana Press, Totowa, NJ, pp. 471-486.

28. E. M. Hiltbold, A. M. Vlad, P. Ciborowski, Simon C. Watkins, and O. J. Finn. Mechanism of unresponsiveness to circulating antigen MUC1 is a block in intracellular sorting and processing by dendritic cells. J. Immunol. 2000, 165:3730-3741.

29. P. Beatty, F-G. Hanisch, D. Beer Stolz, O.J. Finn, and P. Ciborowski. Biochemical characterization of the soluble form of tumor antigen MUC1 isolated from sera and ascites fluid of breast and pancreatic cancer patients. Clin. Canc. Res. 2001, 7:781s-787s.

30. H. Kao, A. A. Amoscato, P. Ciborowski, and O. J. Finn. A new strategy for tumor antigen discovery on in vitro priming of naïve T cells with dendritic cells. Clin. Canc. Res. 2001, 7:773s-780s.

31. M. Soares, F-G. Hanisch, O.J.Finn, and P. Ciborowski. Recombinant human tumor antigen MUC1 expressed in insect cells: structure and immunogenicity. Prot. Expr. Purif. 2001, 22:92-100.

32. P. Ciborowski and O.J. Finn. Non-glycosylated tandem repeats of MUC1 facilitate attachment of breast tumor cells to normal human lung tissue and immobilized extracellular matrix proteins (ECM) in vitro: potential role in metastasis. Clin & Exp. Metastasis 2002, 19:339-345.

33. K.A. Carlson, P. Ciborowski, C. Schellpeper, T. M. Biskup, R.F. Shen, X. Luo, C. J. Destache, and H.E. Gendelman, Proteomic fingerprinting of HIV-1-infected human monocyte-derived macrophages: A preliminary report. J. Neuroimmunol. 2004, 147:35-42.

34. P. Ciborowski*, Y. Enose, A. Mack, M. Fladseth, and H. Gendelman. Diminished matrix metalloproteinase 9 secretion in human immunodeficiency virus infected mononuclear phagocytes:

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modulation of innate immunity and implications for neurological disease. J. Neuroimmunol. 2004, 157:11-16. *- corresponding author

35. Y. Enose, C. Destache, A. Mack, J. Anderson, F. Ullrich, P. Ciborowski, and H. Gendelman. Proteomic Fingerprints Distinguish Microglia, Bone Marrow and Spleen Macrophage Populations. Glia. 2005, 51:161-172.

36. P. Ciborowski* and H.E. Gendelman. Human Immunodeficiency Virus – Mononuclear Phagocyte Interactions: Emerging Avenues of Biomarker Discovery Modes of Viral Persistence and Disease Pahtogenesis. Curr HIV Res. 2006, 4:279-91. *- corresponding author.

37. M. Ricardo-Dukelow, I. Kadiu-Kieken, W. Rozek, J. Schlautman, Y. Persidsky, P. Ciborowski, G. D. Kanmogne, H. E. Gendelman. HIV-1 infected monocyte-derived macrophages affect the human brain microvascular endothelial cell proteome: New insights into blood-brain barrier dysfunction for HIV-1-associated dementia. J. Neuroimmunol., 2007,185:37-46

38. P. Ciborowski*, I. Kadiu, W. Rozek, K. Bernhardt, M. Fladseth, M. Ricardo-Dukelow, and H.E. Gendelman. The Human Immunodeficiency Type One-Infected Monocyte-Derived Macrophage Secretome. Virology. 2007, 363:198-209, *- corresponding author.

39. J. G. Glanzner, E. Enose, T. Wang, I. Kadiu, N. Gong, W. Rozek, J. Liu, J. D. Shlautman, P. Ciborowski, M.P. Thomas, and H.E. Gendelman. Genomic and Proteomic Microglial Profiling: Pathways for Neuroprotective Inflammatory Responses Following Nerve Fragment Clearance and Activation, J. Neurochem., 2007, 102:627-645.

40. I. Kadiu, M. Ricardo-Dukelow, P. Ciborowski, and H. E. Gendelman. Cytoskeletal protein transformation in HIV-1 infected macrophage giant cells. J. Immunol., 2007, 178:6404-15.

41. W. Rozek, M. Ricardo-Dukelow, S. Holloway, V. Wojna, L. Melendez, and P. Ciborowski. Cerebrospinal fluid proteomic profiling of HIV-1-infected patients with or at risk for cognitive impairments. J. Proteome Res. 2007, 6:4189-99.

42. J. Perez Laspiur, E. Anderson, P. Ciborowski, V. Wojna. F. Duai, R. Mayo, E. Rodriguez, M. Plaud-Valentin, J. Rodriguez-Orengo, H.E. Gendelman, L.M. Melendez. CSF Proteomic Fingerprints for HIV-associated Cognitive Impairment. J. Neuroimmun. 2007, 192:157-70.

43. A. Reynolds, J. Glanzer, I. Kadiu, M. Ricardo-Dukelow, A. Chaudhuri, P. Ciborowski, R. Cerny, B. Gelman, M. P. Thomas, R. L. Mosley, and H. E. Gendelman. Nitrated alpha synuclein-activated microglial profiling for Parkinson’s disease. J Neurochem. 2008, 104:1504-25.

44. C. C. Caswell, R. Han, K. M. Hovis, P. Ciborowski, D. R. Keene, R. T. Marconi and S. Lukomski. Scl1 protein of M6-type group A Streptococcus binds the human complement regulatory protein, factor H, and inhibits the alternative pathway of complement. Mol Microbiol. 2008, 67:584-96.

45. E.J. Benner, R. Banerjee, A.D. Reynolds, S. Sherman, V.M. Pisarev, V. Tsiperson V, C. Nemachek, P. Ciborowski, S. Przedborski, R.L. Mosley, H.E. Gendelman. Nitrated alpha-Synuclein Immunity Accelerates Degeneration of Nigral Dopaminergic Neurons. PLoS ONE. 2008, 3(1):e1376.

46. A.D. Reynolds, I. Kadiu, S.K. Grag J. G. Glanzer, T. Nordgren, P. Ciborowski, R. Banerjee, and H.E. Gendelman. Nitrated Aplha-Synuclein and microglial neuroregulatory activities. J. Neuroimmune Pharmacol. 2008, 3:59-74.

47. T. Wang, N. Gong, J. Liu, I. Kadiu, S. D. Kraft-Terry, R. L. Mosley, D. J. Volsky, P. Ciborowski, and H. E. Gendelman. Proteomic Modeling for HIV-1 Infected Microglia-Astrocyte Crosstalk. PLoS ONE. 2008, 3(6):e2507.

48. T. Wang, N. Gong, J. Liu, I. Kadiu, S. D. Kraft-Terry, J. D. Schlautman, P. Ciborowski, D. J. Volsky, and H. E. Gendelman. HIV-1 infected astrocytes and the microglial proteome. J. Neuroimmune Pharmacol. 2008, 3(3):173-86.

49. C. Luciano-Montalvo, P. Ciborowski, F. Duan, H. E. Gendelman, L. M. Meléndez. Proteomic analyses associate cystatin B with restricted HIV-1 replication in placental macrophages. Placenta, 2008, 29:1016-1023.

50. S. Sato, J. Xu, S. Okuyama, L. B. Martinez, S. M. Walsh, M. T. Jacobsen, R. J. Swan, J. D Schlautman, P. Ciborowski, and T. Ikezu. Spatial learning impairment, enhanced CDK5/p35 activity, and down-regulation of NMDA receptor expression in transgenic mice expressing tau-tubulin kinase 1. J. Neuroscience, 2008, 28:14511-14521.

51. W. Rozek, J. Horning, J. Anderson, and P. Ciborowski. Sera Proteomic Biomarker Profiling in HIV-1 Infected Subjects with Cognitive Impairment. Proteomics – Clinical Applications, 2008, 2:1484-1507. Publication was accepted before April 7, 2008.

52. J. D. Schlautman, W. Rozek, R.L. Mosley, R. Stettler, H. E. Gendelman, and P. Ciborowski. Multidimensional Protein Fractionation Using ProteomeLab PF2D for Profiling Amyotrophic Lateral Sclerosis Immunity: A Preliminary Report. Proteome Science, 2008, 12, 6:26-38. PMCID: PMC2543004

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53. D.M. Toro-Nieves, Y. Rodriguez, M. Plaud, P. Ciborowski, F. Duan, J. Pérez-Laspiur, V. Wojna, and L. Meléndez. Proteomic analyses of monocyte-derived macrophages infected with HIV-1 primary isolates from Hispanic women with and without cognitive impairment. J. Neurovirology, 2009, 15:36-50. PMCID: PMC2947716.

54. L. B. Martinez, S. M. Walsh, M. T. Jacobsen, S. Sato, J. Wiederin, P. Ciborowski and T. Ikezu. Calpain and Proteasomal Regulation of Antiretroviral Zinc Finger Protein OTK18 in Human Macrophages: Visualization in Live Cells by Intramolecular FRET. J. Neuroimmune Pharmacology, 2009, 4:116-128. PMCID: PMC2644346.

55. J. Wiederin, F. Duan, W.Rozek and P. Ciborowski. Biomarkers of HIV-1 Associated Neurocognitive Disorders: Proteomic Investigation of Sera, Proteome Science, 2009, 7:8. PMCID: PMC2666658

56. I. Kadiu, T. Wang, J.D. Shlautman, L. Dubrosky, P. Ciborowski, M. Bukrinsky and H.E. Gendelman. HIV-1 transforms the monocyte plasma membrane proteome, Cell. Immunol. 2009, 258:44-58. PMCID: PMC2746502.

57. P. Ciborowski. Biomarkers of HIV-1 Associated Neurocognitive Disorders: Challenges of Proteomic Approaches. Biomarkers in Medicine. 2009, 3:771-785. PMC Journal - in Process

58. J. Silberring and P. Ciborowski. Biomarker discovery and clinical proteomics, Trends in Analytical Chemistry, 2010, 29:128-140. PMCID: PMC2822390.

59. S. Kraft-Terry, Y. Rodriguez, M. Plaud, P. Ciborowski, F. Duan, J. Pérez-Laspiur, V. Wojna, H.E. Gendelman and L. Meléndez. Proteomic analyses of monocytes obtained from Hispanic women with HIV-associated dementia show depressed antioxidants", Proteomics - Clinical Applications, 2010, 4:706-714. PMCID: PMC3098323.

60. G. Pottiez, N. Haverland and P. Ciborowski. Mass spectrometry characterization of gelsolin isoforms. Rapid Communications in Mass Spectrometry, 2010, 24:2620-2624. PMCID: PMC3286873.

61. J. Wiederin, R. Donahoe, J. Anderson, F. Yu, H. Fox, H.E. Gendelman, and P. Ciborowski. Plasma Proteomic Fingerprinting Reflects Simian Immunodeficiency Virus Infection in Rhesus Macaques. J. Proteome Res., 2010, 9:4721-4731. PMCID: PMC3285256.

62. X-M. Liu, L-d. Quan, J. Tian, F.C. Laquer, P. Ciborowski and D. Wang. The Syntheses of Click PEG – Dexamethasone Conjugates for the Treatment of Rheumatoid Arthritis. Biomacromolecules, 2010, 11:2621-2628. PMCID: PMC2966310.

63. N. Haverland, G. Pottiez, J. Wiederin, and P. Ciborowski. Immunoreactivity of anti-gelsolin antibody: Implications for biomarker validation. Journal of Translational Medicine, 2010, 8:137. PMCID: PMC3019187.

64. S.D. Kraft-Terry, I. L. Engebretsen, D. K. Bastola, H. S. Fox, P. Ciborowski, and H. E. Gendelman Pulsed stable isotope labeling of amino acids in cell culture demonstrate dynamic interactions between HIV-1 and the monocyte-derived macrophage. J. Proteome Res. 2011, 3:2852-2862. PMCID: PMC3108467.

65. J. Wiederin, R. Donahoe, J. Anderson, F. Yu, H. Fox, P. Ciborowski* and H.E. Gendelman. Changes in the Plasma Proteome Follows Chronic Opiate Administration In Simian Immunodeficiency Virus Infected Rhesus Macaques. Drug and Alcohol Dependence, 2012, 120:105-12, PMCID: PMC3245805. *- corresponding author.

66. G. Pottiez and P. Ciborowski. Elucidating gelsolin interacting domains using chemical cross-linking and MALDI-TOF/TOF mass spectrometry. Analytical Biochemistry 2012, 421:712-8. PMCID:PMC3287059.

67. P. Swanson, M. Kassmeier, K. Mondal, V. Palmer, P. Raval, S. Kumar, G. Perry, D. Anderson, P. Ciborowski, S. Jackson, and Y. Xiong. "VprBP binds full-length RAG1 and is required for B cell development and V(D)J recombination fidelity" EMBOJ, 2011, 31:945-58. PMCID: PMC3280554.

68. G. Pottiez, T. Jagadish, F. Yu, S. Letendre, R. Ellis, N.A. Duarte, I. Grant, H.E. Gendelman, H.S. Fox and P. Ciborowski. Plasma Proteomic Profiling in HIV-1 Infected Methamphetamine Abusers. PLoS One. 2012; 7:e31031, G. Pottiez, T. Jagadish, F. Yu, S. Letendre, R. Ellis, N.A. Duarte, I. Grant, H.E. Gendelman, H.S. Fox and P. Ciborowski. Plasma Proteomic Profiling in HIV-1 Infected Methamphetamine Abusers. PLoS One. 2012; 7:e31031, PMCID: PMC3281056.

69. T. Jagadish, G. Pottiez, H.S. Fox and P. Ciborowski. Plasma gelsolin accumulates in macrophage nodules in brains of Simian Immunodeficiency Virus infected rhesus macaques. J Neurovirol. 2012, 18(2):113-9, PMCID: PMC 3796665.

70. Pottiez G, Wiederin JL, Fox H, Ciborowski P. Comparison of 4-plex to 8-plex iTRAQ® quantitative measurements of proteins in human plasma samples. J Proteome Res. 2012 11:3774-81 PMCID: PMC3390908.

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71. C. C. Caswell, J. M. Gaines, P. Ciborowski, D. Smith, C. H. Borchers, C. M. Roux, P. M. Dunman, and R. M. Roop. Identification and characterization of two small regulatory RNAs linked to virulence in Brucella abortus 2308. Molecular Microbiology – 2012, 85:345-60, PMCID: PMC3391331.

72. H. Peng, Y. Wu Y, Z. Duan, P. Ciborowski, J.C. Zheng. Proteolytic processing of SDF-1α by matrix metalloproteinase-2 impairs CXCR4 signaling and reduces neural progenitor cell migration. Protein Cell. 2012 Nov; 3(11):875-82. PMCID: PMC3973535.

73. C.J. Schweitzer, T. Jagadish T, N. Haverland, P. Ciborowski, M. Belshan M. Proteomic analysis of early nucleoprotein complexes. J Proteome Res. 2013, (2):559-72, PMCID: PMC3564510.

74. P. Olszowy, A. Burns and P. Ciborowski. Pressure-assisted sample preparation for proteomic analysis. Analytical Biochemistry. 2013, 438:67-72, PMCID: PMC3761939.

75. A. Drabik, A. Bodzoń-Kułakowska, P. Suder, P. Ciborowski and J. Silberring. iTRAQ analysis with Paul ion trap - obstacle solved. J Proteome Res. 2013, 12:4607-11. Aug 31. PMC Journal - in Process.

76. N. Haverland, H. Fox and P. Ciborowski. Quantitative proteomics by SWATH-MS reveals altered expression of nucleic acid binding and regulatory proteins in HIV-1-infected macrophages. J Proteome Res. 2014, 13:2409 - 19. PMCID: PMC3993959.

77. J. Wooden and P. Ciborowski. Chromatin Immunoprecipitation for Human Monocyte Derived Macrophages. Methods 2014, 70:89-96. PMCID: PMC4268110.

78. J. DeBoer, T. Jagadish, N.A. Haverland, Ch. Madson, P. Ciborowski, M. Belshan. Alterations in the nuclear proteome of HIV-1 infected T-cells. Virology, 2014, 18:468-470. PMCID: PMC4253593.

79. M. Arainga, D. Guo, J. L.Wiederin, P. Ciborowski, J-E. McMillan, and H. E. Gendelman. Opposing Regulation of Endolysosomal Pathways by Long-Acting Nanoformulated Antiretroviral Therapy and HIV-1 in Human Macrophages – Retrovirology, 2015, Jan 22;12:5. doi: 10.1186/s12977-014-0133-5. PMCID: PMC4307176.

80. MR. Donelly and P. Ciborowski. HIV, Proteomics and Biomarkers: Current perspective. Proteomics – Clinical Applications, 2015, Jun 1. doi:10.1002/prca.201500002. [Epub ahead of print].

81. A. Burns and P. Ciborowski. Acute exposure to methamphetamine alters TLR9 mediated cytokine expression in human macrophage. Immunobiology – in press.

82. Y. Li, K. M. Frederick, N. A. Haverland, P. Ciborowski, and Michael Belshan. Investigation of the HIV-1 Matrix interactome during virus replication. Proteomics – Clinical Applications, 2015, accepted.

83. P. Olszowy and P. Ciborowski. Profiling Post-translational Modifications of Histones in Human Monocyte-derived Macrophages. Proteome Science, 2015, in press.

84. G. Zhang, D. Guo, P. K. Dash, M. Araínga, J. L. Wiederin, N. A Haverland, J. Knibbe-Hollinger, A. Martinez-Skinner, P. Ciborowski, V. S. Goodfellow, T. A. Wysocki, B. J. Wysocki, L. Y. Poluektova, X-M. Liu, J-E. M. McMillan, S. Gorantla, H. A. Gelbard and H. E. Gendelman. The Mixed Lineage Kinase-3 Inhibitor URMC-099 Improves Therapeutic Outcomes for Long-Acting Antiretroviral Therapy, Nanomedicine, 2015 – accepted.

85. Ricaurte M, Schizas NV, Ciborowski P, Boukli NM. Proteomic analysis of bleached and unbleached Acropora palmata, a threatened coral species of the Caribbean. Mar Pollut Bull. 2016 Jun 15;107(1):224-32. doi: 10.1016/j.marpolbul.2016.03.068. PMID:2710572. 

86. Bachert BA, Choi SJ, LaSala PR, Harper TI, McNitt DH, Boehm DT, Caswell CC, Ciborowski P, Keene DR, Flores AR, Musser JM, Squeglia F, Marasco D, Berisio R, and Lukomski S. Unique Footprint in the scl1.3 Locus Affects Adhesion and Biofilm Formation of the Invasive M3-Type Group A Streptococcus. Front Cell Infect Microbiol. 2016 Aug 31;6:90. doi: 10.3389/fcimb.2016.00090. PMID: 27630827 

87. Embury CM, Dyavarshetty  B, Lu Y, Wiederin JL, Ciborowski P, Gendelman HE and Kiyota T. Cathepsin B Improves -Amyloidosis and Learning and Memory in Models of Alzheimer’s Disease. J Neuroimmune Pharmacol. 2016 – accepted.

88. Ciborowski P, Fox HS. Proteomics and HIV. Proteomics Clin Appl. 2016 Feb;10(2):109. doi: 10.1002/prca.201670023.

89. Ubaida-Mohien, Ceereena; Lamberty, Benjamin; Dickens, Alex M.; Mielke, Michelle M.; Marcotte, Thomas; Sacktor, Ned; Grant, Igor; Letendre, Scott; Franklin, Donald; Ciborowski, Pawel; Tharakan, Ravi; McArthur, Justin C.; Fox, Howard; Haughey, N.J. Modifications in acute phase and complement systems predict shifts in cognitive status of HIV-infected patients. AIDS. 31(10):1365-1378, June 19, 2017.

90. Sharma, Anup; Horning, Jayme; Uz, Metin; Ciborowski, Pawel; Mallapragada, Surya; Gendelman, Howard; Sakaguchi, Donald S. Proteomic Analysis of Mesenchymal to Shwann cell trans differentiation. Journal of Proteomics, 2017.

Book Chapters:

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1. K. Pawlak, E. Harwood, F. Yu and P. Ciborowski. “Multidimensional data analysis based on mass spectra” in: “Mass spectrometry for graduates: A user oriented approach” P. Suder, M. Smoluch, G. Grasso and J. Silberring eds. Wiley, Inc. 2018

2. P. Ciborowski and Jerzy Silberring. Co-editors. The cross-roads of proteomics and analytical chemistry. Second Edition, Elsevier, Inc. 2016.

3. N. A. Haverland, L. M. Villeneuve, P. Ciborowski, and H. S. Fox. The proteomic characterization of plasma or serum from HIV-infected patients. HIV Protocols: Third Edition. V. R. Prasad and G. V. Kalpana eds. Humana Press, Inc. 2015.

4. P. Ciborowski and Jerzy Silberring. Co-editors. The cross-roads of proteomics and analytical chemistry. First Edition, Elsevier, Inc. 2013.

5. M. Wojtkiewicz, K. Barnett and P. Ciborowski. Protein identification by mass spectrometry: Proteomics. In:Current Laboratory Methods in Neuroscience Research. Huangui Xiong, and Howard E. Gendelman, eds. Springer, Inc. 2012.

6. G, Pottiez, and P. Ciborowski. Proteomic Profiling of Cerebrospinal Fluid. In: Expression Profiling in Neuroscience. (Y. Karamanos, ed.) Humana Press, Inc. 2011.

7. N, Haverland, and P. Ciborowski. Protein Profiling of the Brain: Proteomics of Isolated Tissues and Cells. In: Expression Profiling in Neuroscience. (Y. Karamanos, ed.) Humana Press, Inc. 2011.

8. M. Wojtkiewicz, and P. Ciborowski. Profiling of HIV proteins in Cerebrospinal Fluid. In: Expression Profiling in Neuroscience. (Y. Karamanos, ed.) Humana press, Inc. 2011.

9. P. Ciborowski and J. Jeljaszewicz. Staphylococcal enzymes and virulence. In: Bacterial Enzymes and Virulence. (I.A. Holder ed.) 1985, CRC Press Inc. Boca Raton, Florida, pp.145-184.

10. W. Hryniewicz and P. Ciborowski. Cerebrospinal fluid. In: Material for bacteriological, parasitological and virological diagnostics. (W. Kantoch ed.) 1987, Polish Medical Publishers, Warsaw, pp. 23-27.

Manuscripts submitted:

1. K. L. Stauch, P. Ciborowski, and H. S. Fox. Comparison of Super-SILAC and SWATH-MS Techniques: Application for Quantifying the Mouse Synaptic Mitochondrial Proteome. Analytical Chemistry – submitted.

2. E. Harwood, F. Yu, N. A. Haverland and P. Ciborowski. Outlier removal in SWATH-MS data processing reduces variability. BMC Systems Biology – submitted.

Patents:1. “Biomarkers for the Diagnosis of Cognitive Impairment” H.E. Gendelman, W. Rozek and P. Ciborowski,

Docket No. 08014P, Serial No. 61/068,171, Filing Date: March 5, 2008.

Abstracts (since joining UNMC in 2003):1. Y. Enose, M.Thomas, A. Mack, P. Ciborowski and H. Gendelman. Microglial fingerprintings, potential

links to neurodegeneration. SNIP Conference, New Mexico, March 2004.2. D.M. Toro-Nievas, E. R. Anderson, M. Plaud, E. Rodriguez, V. Wojna, P. Ciborowski, H. E. Gendelman,

and L. M. Meléndez-Guerrero. HIV primary isolates and monocyte proteome in women with cognitive impairment. 2004.

3. P. Ciborowski, Y. Enose, I. Kadiu,. M. Fladseth, and H.E. Gendelman. Secretome of HIV-1 Infected Monocyte Derived Macrophages: Links to the Neuropathogenesis of HIV Infection. Keystone Symposium, Snow Bird, Utah, February 2005.

4. P. Ciborowski, Y. Enose, and H. E. Gendelman. Defining the mononuclear phagocyte proteome in health and disease. 1st USHUPO, Washington, D.C. March 2005.

5. I. Kadiu, H. E. Gendelman, and P. Ciborowski. Proteomic Analysis of HIV-1 Infected Macrophages: Links to Biomarker Discovery for HIV-1 Associated Dementia. SfN Annual Meeting, Washington, D.C. November 2005.

6. P. Ciborowski, I. Kadiu, M. Ricardo-Dukelow, K. Bernhardt, M. Fladseth, and H.E. Gendelman. Definign the HIV-1 Infected macrophage Proteome, CROI, Denver, CO, February 2006.

7. P. Ciborowski, I. Kadiu, M. Ricardo-Dukelow, K. Bernhardt, M. Fladseth, and H.E. Gendelman. Defining the HIV-1 Infected Macrophage Proteome. 13th CROI, Denver, CO, February 5-8, 2006.

8. W. Rozek and P. Ciborowski. Proteomic profiling of cerebrospinal fluids from individuals with HIV-1 Associated Dementia. 2US HUPO, Boston, MA, March 12-15, 2006.

9. P. Ciborowski, I. Kadiu, M. Ricardo-Dukelow, K. Bernhardt, M. Fladseth, and H.E. Gendelman. Defining The HIV-1 Infected Macrophage Proteome. 2US HUPO, Boston, MA, March 12-15, 2006. – oral presentation.

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10. M.Ricardo-Dukelow, P.Ciborowski, B. Mosley, Y. Persidsky, W. Rozek, I. Kadiu, H.E.Gendelman, G. Kanmogne. A proteomic fingerprint of brain microvascular endothelial cells (BMVEC) and HIV-1 infected macrophage secretions: a model for blood brain barrier (BBB) dysfunction in neuroAIDS. 12th SNIP Conference, Santa Fe, NM, April 5-9, 2006.

11. J. Pérez Laspiur, E. R. Anderson, P. Ciborowski, H. E. Gendelman, V. Wojna, J. Rodríguez-Orengo, E. Rodríguez, J. Anderson, and L. M. Meléndez-Guerrero. CSF Biomarkers for HIV-1 Associated Dementia in Hispanic Women. 12th SNIP Conference, Santa Fe, NM, April 5-9, 2006.

12. W. Rozek, M. Ricardo-Dukelow, H. E. Gendelman, L. Melendez, P. Ciborowski. Proteomic fingerprints for HIV-1 cognitive impairments. 8th International Symposium on NeuroVirology, San Diego, CA, October 29-Nov 2, 2007.

13. I. Velasquez, M. Plaud, J. Perez Laspiur, V. Wojna, R. Skolasky, P. Ciborowski, H.E. Gendelman, L M. Meléndez. Dysregulation of Cu/Zn Superoxide Dismutase-1 in the CSF and monocytes of Hispanic women with cognitive impairment. 8th International Symposium on NeuroVirology, San Diego, CA, October 29-Nov 2, 2007.

14. T. Wang, N. Gong, I. Kadiu, J. Liu, J. D. Schlautman, D. J. Volsky, P. Ciborowski, and H. E. Gendelman. Microglia-astrocyte crosstalk and the neuropathogenesis of HIV-1 infection. 37th SfN Neuroscience, San Diego, CA, November 3 – 7, 2007.

15. W. Rozek, J. Horning, J. Anderson, and P. Ciborowski. Proteomic profiling of sera from patients with HIV-1 Associated Dementia. 4th USHUPO, Bethesda, MD, March 16-19, 2008.

16. H. Peng, Y. Wu, P. Ciborowski, and J. Zheng. Matrix metalloproteinase-2 proteolysis regulates SDF-1 signaling and function on neural progenitor cell: relevance to HIV-1-associated dementia SfN Annual Meeting, Washington D.C., November 15-19, 2008.

17. L.M. Melendez, M. Plaud, P. Ciborowski, J. Perez Laspiur, E. Rodriguez, F. Duan, V. Wojna, and H.E. Gendelman. Novel Mechanisms of HIV Associated Neurological Disorders and Biomarker Discovery Using Proteomics. 7th Conference of the Specialized Neuroscience Research Programs, New York, NY, August 19-22, 2008.

18. L.M. Melendez, M. Plaud, S. Kraft, P. Ciborowski, J. Perez Laspiur, E. Rodriguez, F. Duan , V. Wojna, and H.E. Gendelman. Biomarker Proteomics Discovery Uncovers Novel Mechanisms for HIV-1 Associated Neurocognitive Disorders. 7th Conference of the Specialized Neuroscience Research Programs, New York, NY, August 19-22, 2008.

19. A. D. Reynolds, D. K. Stone, R. Banerjee, P. Ciborowski, R. L. Mosley, and H. E. Gendelman. Mechanisms for Regulatory T-cell Neuroprotection During Nitrated Alpha Synuclein Microglial Neurotoxic Responses. NV Conference, Fort Worth TX, 2008.

20. S. Kraft-Terry, Y. Gerena, J. Pérez-Laspiur, M. Plaud-Valentin, P. Ciborowski, V. Wojna, F. Duan, H. Gendelman and L. M. Meléndez. Monocyte proteomics reveals depressed antioxidant system in Hispanic women with HIV-cognitive impairment. 11th RCMI International Symposium on Health Disparities, Honolulu, Hawaii, December 1-4, 2008.

21. J. Wiederin, F. Duan, W. Rozek, and P. Ciborowski. HIV-infected patients with neurocognitive impairments: Proteomic fingerprints of serum/plasma and CSF. 57th ASMS Conference on Mass Spectrometry, Philadelphia, Pennsylvania, May 30 – June 4, 2009

22. J. Wiederin, W. Rozek, H. Pan, T. Jagadish, S. Banerjee, F. Vaida, S. Letendre, R. Ellis, I. Grant, H. Fox, H.E. Gendelman and P. Ciborowski. Proteomic fingerprints in CSF and blood of HIV-infected patients with neurocognitive disorders. The 9th International Symposium on NeuroVirology, Miami Beach, Florida, June 2-6, 2009.

23. G. Pendyala, S.A. Trauger, E. Kalisiak, R. Ellis, P. Ciborowski, H.E. Gendelman, G. Siuzdak, H.S. Fox. Proteomic profiling of cerebrospinal fluid reveals potential neuropathogenic changes in neuroAIDS. The 9th International Symposium on NeuroVirology, Miami Beach, Florida, June 2-6, 2009.

24. G. Pendyala, S.A. Trauger, P. Ciborowski, H.E. Gendelman, G. Siuzdak, H.S. Fox. Organelle based proteomics of the caudate nucleus in a SIV/METH monkey model. HUPO, Toronto, Canada, September 23-25, 2009.

25. G. Pottiez, T. Jagadish, I. Grant, R. Ellis, S. Letendre, J.Wiederin, H.S. Fox, P. Ciborowski. Short and long term effect of methamphetamine withdrawal: Proteomic profiling of plasma from HIV-infected patients. USHUPO, Denver, CO, March 7-10.2010.

26. J. Wiederin, R. Donahoe, H.S. Fox, H.E. Gendelman, P. Ciborowski. Plasma proteomics analysis of acute and chronic phase of simian immunodeficiency virus infection of Rhesus macaques. USHUPO, Denver, CO, March 7-10.2010.

27. M. Wojtkiewicz (Fittje), P. Ciborowski. Mass Spectrometry and Proteomics Core Facility. ABRF 2010, Sacramento, CA, March 20-23, 2010.

11

28. C. C. Caswell, J. M. Gaines, P. Ciborowski and R. M. Roop II. . The RNA chaperone HFQ represses the production of a putative periplasmic protein of unknown function in Brucella abortus 2308. 54th Annual Wind River Conference on Procaryotic Biology, Estes Park, CO, June 2-6, 2010.

29. M. Wojtkiewicz, S. Wolfe, and P. Ciborowski. UNMC Mass Spectrometry and Proteomics Core Facility. NIH, NCRR Third Biennial National IDeA Symposium of Biomedical Research Excellence (NISBRE) Bethesda, MD, June 16 - 18, 2010.

30. G. Pottiez, J. Wiederin, R. Donahoe, H.S. Fox, H.E. Gendelman, P. Ciborowski. Plasma and Cerebrospinal Fluid Profiling for HIV-Associated Neurocognitive Disorders. HUPO 2010, Sydney, Australia, September 19-24, 2010.

31. G. Pottiez, T. Jagadish, I. Grant, R. Ellis, S. Letendre, H. Fox and P. Ciborowski Short and long term effect of methamphetamine withdrawal: Proteomic profiling of plasma from HIV-infected patients. 10 th

International Symposium on NeuroVirology. Milan, Italy, 12-16 October, 2010.32. G. Pottiez and P. Ciborowski. Characterization of gelsolin-fibronectin interaction by MALDI-TOF/TOF

mass spectrometry. ASMS Sanibel Conference “From Fragmentation Mechanisms to Sequencing:  Tandem Mass Spectrometry Based Peptide and Protein Identification. St. Pete Beach, FL. January 21 - 24, 2011.

33. G. Pottiez, A. Burns, N. Haverland, W. Rozek and P. Ciborowski. Mass spectrometric characterization of gelsolin and its interacting domains. ASMS Conference on Mass Spectrometry and Allied Topics. Denver, CO, June 5 - 9, 2011.

34. P. Ciborowski, C. Schweitzer, T. Jagadish, R. Dominic Savio and Mike Belshan. Mass spectrometric characterization of the HIV-1 preintegration complex. ASMS Conference on Mass Spectrometry and Allied Topics. Denver, CO, June 5 - 9, 2011.

35. M. Wojtkiewicz and P. Ciborowski. Mass Spectrometry and Proteomics Core Facility. ABRF 2011, San Antonio, TX, February 19 - 22, 2011.

36. P. Ciborowski, M. Wojtkiewicz and K. Barnett. University of Nebraska Medical Center, Mass Spectrometry and Proteomics Core Facility. The Midwest Association of Core Directors (Chapter of ABRF) Second Annual Meeting. Chicago, IL, October 27 – 30, 2011.

37. Pottiez G, Burns A, Haverland N, Rozek W and Ciborowski P. Mass spectrometric characterization of gelsolin and its interacting domains. The 59th American Society of Mass Spectrometry Conference on Mass Spectrometry and Allied Topics in Denver, CO. June 2011.

38. Haverland N and Ciborowski P. A systems biology approach for understanding the host response in macrophagesfollowing HIV-1 infection. The 7th Annual International Student Research Forum in Tokyo, Japan. October 2011.

39. Haverland N, Burns A, Pottiez G and Ciborowski P. Exposing Alterations in the Nuclear Proteome in HIV-infected Human Monocyte-derived Macrophages. International Conference & Exhibition in Virology-2011 hosted by the Omics Group in Baltimore, MD. September 2011.

40. G. Pottiez, M. Wojtkiewicz and P. Ciborowski. Chemical cross-linking and MALDI-TOF/TOF to investigate protein interacting domain. ABRF 2012, Orlando, FL, March 17 - 20, 2012.

41. G. Pottiez, J. Wiederin, H. Fox and P. Ciborowski. Comparisons of 4-plex to 8-plex iTRAQ® quantitative measurements of proteins in human plasma. Vancouver, Canada, May 20 - 24, 2012.

42. T. Jagadish, N. Haverland, G. Pottiez, J. Wiederin, H. Fox and P. Ciborowski. Plasma Gelsolin and HIV-1 Infected Macrophage: Implications for Chronic Neuroinflammation. 11th International Symposium on NeuroVirology. New York, NY, May 29 – June 2, 2012.

43. P. Olszowy and P. Ciborowski. HIV, methamphetamine and combination antiretroviral therapy: Profiling of histones modification, 2nd World Congress on Virology, Las Vegas, NV, August 20-22, 2012.

44. A. Burns and P. Ciborowski. Expression of histone deacetylases and acetyltransferases in HIV 1 infected monocyte-derived macrophages. 2nd World Congress on Virology, Las Vegas, NV, August 20-22, 2012.

45. P. Olszowy, A. Burns and P. Ciborowski. Pressure assisted digestion of histones for proteomic analysis. 29th International Symposium on Chromatography ISC 2012, September 9-13, 2012, Torun, Poland.

46. N. Haverland and P. Ciborowski. A holistic approach for understanding the host response in macrophages following HIV-1 infection. The Gordon Conference for Cellular Systems Biology. Davidson, NC. July 2011.

47. N. Haverland and P. Ciborowski. Elucidating the host response in monocyte-derived Macrophages following HIV infection: a systems biology-based approach. The 8th International Workshop for HIV, Cells of Macrophage / Dendritic Lineage, and other Reservoirs: Pathogenic and Therapeutic Implications in Stresa, Italy. May 10-12, 2012.

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48. G. Zhang, P. Dash, J. Wiederin, P. Ciborowski, V. S. Goodfellow, J-E McMillan, S. Gorantla, L. Poluektova, H. Gelbard and H. E. Gendelman. URMC-099: A New Drug Formulation With Early But Substantive Antiretroviral and Immune Preservative Functions for HIV/AIDS. CROI 2013.

49. P. Olszowy, M. Wojtkiewicz, J. Wiederin, P. Ciborowski. Comparison of software packages for analysis of phosphoproteome. ABRF 2013 Conference, Palm Springs, CA, March 2 – 5, 2013.

50. P. Olszowy, A. Burns and P. Ciborowski. Post-translational modifications of Histone H4 in Human Immunodeficiency Virus-1 infected human macrophages exposed to methamphetamine and antiretroviral drugs. 19th SNIP Scientific Conference, Puerto Rico, PR, April 3 – 6, 2013.

51. P. Olszowy and P. Ciborowski. CID and ETD based profiling of posttranslational modifications of histones in human monocyte derived macrophages. 61st ASMS Annual Conference, Minneapolis, MN, June 9 – 13, 2013.

52. J. Wiederin, M. Wojtkiewicz, P. Olszowy and P. Ciborowski. Maximizing Phosphoproteome Profiling Using Mascot, PEAKS Studio, Proteome Discoverer and OMSSA Software Packages. 61st ASMS Annual Conference, Minneapolis, MN, June 9 – 13, 2013.

53. M. Wojtkiewicz, J. Winkler, J. Wiederin, L. Villeneuve, K. Stauch, H. S. Fox and P. Ciborowski. Developing Peptide Library for SWATH™ Based Proteomic Profiling. 61st ASMS Annual Conference, Minneapolis, MN, June 9 – 13, 2013.

54. P. Olszowy and P. Ciborowski. Profiling of posttranslational modifications of histones in human monocyte derived macrophages exposed to LPS and/or methamphetamine. Gordon Research Conference, Hong Kong, China, July 28 – Aug 2, 2013.

55. N. Haverland and P. Ciborowski. Global analysis of transcription regulator proteins reveals novel insights into altered cell signaling cascades in HIV-1-infected macrophages. Gordon Research Conference, Hong Kong, China, July 28 – Aug 2, 2013.

56. N. Haverland and P. Ciborowski. Targeted quantitative proteomics (SWATH-MS) reveals novel insights for reprogramming of transcription regulator proteins in HIV-1-infected macrophages. 12th International Symposium on NeuroVirology, Washington DC, October 29 – Nov 2, 2013.

57. G. Zhang, P. K. Dash, D. Guo J. L. Wiederin, P. Ciborowski, V. S. Goodfellow, J-E. McMillan, S. Gorantla, H. A. Gelbard and H. E. Gendelman. NanoART Facilitated HIV-1 Clearance by a Mixed-Lineage Kinase 3 Inhibitor. CROI 2014 March 3 - 6, 2014, Boston, MA.

58. G. Zhang, P. K. Dash, J. L. Wiederin, P. Ciborowski, V. S. Goodfellow, J-E. McMillan, S. Gorantla, L. Poluektova, H. A. Gelbard and H. E. Gendelman. URMC-099: A New Drug Formulation With Early But Substantive Antiretroviral and Immune Preservative Functions for HIV/AIDS. CROI 2014 March 3 - 6, 2014, Boston, MA.

59. K. L. Stauch, P. Ciborowski and H. S. Fox. Comparison of Super-SILAC and SWATH-MS Techniques: Application for Quantifying the Mouse Synaptic Mitochondrial Proteome. HUPO 2014, October 5 – 8 2014, Madrid, Spain.

60. N. A. Haverland, H. S. Fox and P. Ciborowski. SWATH-MS for quantitative proteomics of nucleic acid binding and regulatory proteins. HUPO 2014, October 5 – 8 2014, Madrid, Spain.

61. S. McMillan, K. Reinsvold, J. Wiederin, M. Wojtkiewicz, W. Li, H. E. Gendelman, L. Poluektova and P. Ciborowski. SWATH-MS Profiling of FFPE Tissue Sections. 63st ASMS Annual Conference on Mass Spectrometry and Allied Topics, St. Louis, MO, May 31 - June 4, 2015.

62. Kristin Frederick, Nicole Haverland, Mahbubul Majumder, P. Ciborowski. Visualization of proteomics data for bioinformatics analyses. The International Chemical Congress of Pacific Basin Societies – Pacifichem 2015, Honolulu, HI, USA, December 15 -20, 2015.

63. Toews, M.L., Schulte, N.A., Dodmane, P.R. Tian, G., Ciborowski, P.S., Bennett, R.G., Hamel, F.G., Heires, A.J., Nordgren, T.M., and Romberger, D.J. The ProS Peptide of Porcine Cathelicidins Is an Active Component of Swine Concentrated Animal Feeding Operations (CAFOs) Dust and a Novel Activator of EGF Receptor Signaling. Submitted for American Thoracic Society Meeting, Washington, DC, May 2017.

Invited Lectures, Seminars, and Participation at Meetings/Conferences/Symposia:

Workshops and conferences invited speaker (Since joining UNMC in 2003):

1. Puerto Rico INBRE and COBRE Symposium. San Juan, Puerto Rico, May 19 – 20, 2017. Invited Speaker2. Department of Chemistry, Polytechnic University of Gdansk, Gdansk, Poland. Invited lecturer for a block of 15

lectures for Interdepartmental Graduate Program. “Mass Spectrometry Based Proteomics” April 11-15, 2016 (fifth invitation since 2011).

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3. The International Chemical Congress of Pacific Basin Societies – Pacifichem 2015, Honolulu, HI, USA, Invited Speaker

4. IV International Conference on Analytical Proteomics – ICAP2015, Lisbon, Portugal 2015, Keynote Speaker5. International symposium NANO Ostrava, Check Republic 20156. Department of Chemistry, Polytechnic University of Gdansk, Gdansk, Poland. Invited lecturer for a block of 15

lectures for Interdepartmental Graduate Program. “Mass Spectrometry Based Proteomics” May 11-15, 20157. Department of Chemistry, Polytechnic University of Gdansk, Gdansk, Poland. Invited lecturer for a block of 15

lectures for Interdepartmental Graduate Program. “Mass Spectrometry Based Proteomics” March 10-14, 2014.

8. Nebraska Symposium on Mass Spectrometry 2013, Invited Speaker9. Department of Chemistry, Polytechnic University of Gdansk, Gdansk, Poland. Invited lecturer for a block of 15

lectures for Interdepartmental Graduate Program. “Mass Spectrometry of Proteins and Peptides” April 15-19, 2013.

10. Invited Speaker, Biomarker Mini-symposium, Omaha, NE, June 5, 2012.11. Chair of Organizing Committee, 2nd World Congress on Virology, Las Vegas, NV, August 20-22, 2012.12. Member of Advisory Board Member of Program Committee, Invited Speaker and Session Chair AnalytiX 2012,

Beijing, March 23 – 25, 2012.13. Invited Speaker, 10th Workshop “Biomolecules – Identifications and Functions” AGH University of Science and

technology, Krakow, Poland, October 20-21, 2011.14. Keynote Speaker , Session Chair and Chair of Organizing Committee, International Conference and Exhibition

on Virology, Baltimore, MD, September 5-7, 2011.15. Department of Chemistry, Polytechnic University of Gdansk, Gdansk, Poland. Invited lecturer for a block of 25

lectures for Interdepartmental Graduate Program. “Cross-roads of Proteomics and Analytical Chemistry” March 7-11, 2011.

16. VIII Polish Conference on Analytical Chemistry “Analytical Chemistry for 21st Century Society” Krakow, Poland, July 4-9, 2010.

17. X International Seminar - Biomolecules – Identifications and Functions. Jagiellonian University, Krakow, Poland, October 15-16, 2009

18. Organizer and co-Chair of session at the 8th Annual Conference of World Human Proteome Organization, Toronto, Canada, September 28-30, 2009.

19. The 9th International Symposium on NeuroVirology, Speaker, Miami Beach, Florida, June 2-6, 2009.20. The Center for Workshops in Chemical Sciences, Georgia State University, Principles of Mass Spectrometry

Based Proteomics, Workshop, San Juan, PR, June 21-26, 200921. IX International Seminar - Biomolecules – Identifications and Functions. “Proteomics: Power of Technology,

Expectations and Reality”, Jagiellonian University, Krakow, Poland, October 16-17, 200822. Cambridge Healthtech Institute, GOT Summit, Proteomic Sample Preparation, Boston, MA, May, 19-21, 200823. The Center for Workshops in Chemical Sciences, Georgia State University, Principles of Proteomics

Workshop, San Juan, PR, July 2-4, 200624. 1st Biennial IDeA Conference, Proteomics Workshop, Washington, D.C., July 20-22, 200625. 2nd USHUPO (United States Human Proteome Organization) Conference, Speaker, Boston, MA, March 12-15,

2006.

Invited lectureships (Since joining UNMC in 2003):

1. Worldwide Webinar, ABSciex Inc. “SWATH-MS for Quantitative Proteomics of Nucleic Acid Binding and Regulatory Proteins” May 6th, 2014.

2. University of Puerto Rico Medical Center, San Juan, PR, USA, “Intersection of analytical chemistry and proteomics: Implications for experimental design, measurements and data interpretation." April, 2012.

3. George Mason University, Monassas, VA, December 2011.4. Creighton University, Omaha, NE, “HIV-1 and Mononuclear Phagocytes: Proteomic Approach to Investigate

Functions of Structural Proteins”, November, 2009.5. University of Nebraska Medical Center, Omaha, NE, Cellular & Integrative Physiology Forum "Proteomics and

Its Application to Questions of Biological Importance", November, 2008.6. Jagiellonian University, Krakow, Poland, “HIV-1 and Mononuclear Phagocytes: Proteomic Approach to

Investigate Their Coexistence”, January, 2008.7. National Veterinary Research Institute, Pulawy, Poland, “HIV-1 and Mononuclear Phagocytes: Proteomic

Approach to Investigate Their Coexistence”, January, 2008.8. University of Puerto Rico Medical Sciences Minisymposium, San Juan, PR, USA, “HIV-1-associated Cognitive

Impairment: Proteomic Approach”, August, 2007.

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9. Jagiellonian University, Krakow, Poland, “HIV Associated dementia: Proteomics Approach”, January, 2007.10. University of Cologne, Cologne, Germany, “HIV Associated dementia: Proteomics Approach”, January, 2007.11. University of Puerto Rico Medical Center, San Juan, PR, USA, “Proteomic Fingerprints of Mononuclear

Phagocytes: Unique Insights into Cellular Diversity and Function in Health and Disease”, July, 2006. 12. Universidad Central del Caribe, Bayamon, Puerto Rico, USA, “Proteomics: a new approach in studying global

protein make-up”, May, 2005.13. National Veterinary Institute, Pulawy, Poland, “Proteomics: a new approach in studying global protein make-

up”, January, 2005.

Before joining UNMC in 2003

1. Georgetown University, Washington, D.C., USA 20032. University of Las Palmas, Las Palmas, Canary Islands, Spain 20013. University of Kiel, Kiel, Germany 19984. University of Cologne, Cologne, Germany 19985. National Laboratory of Vaccines, Warsaw, Poland 19976. National Institute of Hygiene, Warsaw, Poland 19967. University of Las Palmas, Las Palmas, Canary Islands, Spain 19958. Postgraduate Medical Training Center, Warsaw, Poland 1994

University of Nebraska seminars:

1. Department of Biochemistry and Molecular Biology, UNMC 20142. Immunology Interest Group, UNMC 20143. Nebraska Center for Virology, UNL 20134. Nebraska Center for the Molecular Biology of Neurosensory Systems,

COBRE, UNMC 20135. Immunology Interest Group, UNMC 20116. Department of Biochemistry and Molecular Biology, UNMC 20097. Department of Cellular and Integrative Physiology, UNMC 20088. Nebraska Center for Virology, UNL 2008

Graduate Student Recruitment Seminars (BRTP, INBRE) and other activities:

1. University of Northern Colorado – Greely, CO 20112. Drake University – Des Moines, IA 20103. Doane College – Crete, NE 20074. Iowa State University, Ames, IA 20075. 2 lectures and MSPCF tours for undergraduate students,

Nebraska Wesleyan University 20076. Missouri State University, Springfield, Missouri, USA 20067. University of Nebraska Lincoln, Lincoln, Nebraska, USA 20058. St. Olaf College, Northfield, Minnesota, USA 2005

Teaching:Current (since joining UMNC):

1. Molecular Structure and Function, Biomedical Research Training Program (BRTP 821), University of Nebraska Medical Center

a. Course co-director (2005 – present)b. Protein Folding I and II – 2 hours (2005 -present)c. Protein – protein interactions – 1 hour (2011 – present)d. Tools for Protein Analysis, Introduction – 1 hour (2007 - present)

2. Receptors and Cell Signaling (PHARM 901), Proteomics and its application to questions of biological importance – 2 hours (2006 - 2012) 4 hours planned starting 2009.

3. Pharmacology for 2nd year medical and pharmacy students, University of Nebraska Medical Centera. Gene Therapy – 1 hour (2007 - present)b. Pharmacogenomics – 1 hour (2007 - present)c. Hematopoietics – 1 hour (2007 - present)

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d. Anticoagulants – 1 hour (2007 - 2011) 2 hours assigned for 20094. Pharmacology for Physician Assistants Students (Pharm 507), University of Nebraska Medical Center

a. 2 hours from 2006 - 2011.5. Pharmacology for Healthcare Professionals (Pharm 470/570), University of Nebraska Medical Center

a. Antiviral agents – 2 hours (2007 – 2011)6. Reproductive Endocrinology, Cellular and Integrative Physiology, University of Nebraska Medical Center

a. Proteomics and its application to questions of biological importance – 2 hours (2008).7. Neuroimmunology (PHAR 930), Proteomics and its application to questions of biological importance – 2

hours (2005, 2010).8. Current methods in Neuroscience (PHAR 820), Proteomics in Neuroscience: lecture and lab exercise – 2

hours (2009).9. Protein Mass Spectrometry and Proteomics (PAMM 950), Proteomic applications in neurodegenerative

diseases – 2 hours (2009)

Past:1. Microbiology (30 lectures and 30 laboratories per semester) - Penn State University, New Kensington

Campus 1994 - 1998.2. Biochemistry Foundation Course – Graduate Program, School of Medicine, University of Pittsburgh,

Pittsburgh - course contributed to.3. Microbial Pathogenesis Course – Graduate Program, School of Medicine, University of Pittsburgh,

Pittsburgh - course contributed to.4. Microbiology, Immunology, Bacterial Pathogenesis - Graduate Periodontics Program, School of Dental

Medicine, University of Pittsburgh, Pittsburgh - course contributed to.

Supervisory & Training:2003 – Present Training more than 15 technicians, graduate students and post-doctoral fellows in use of mass

spectrometry2007 – 2016 Training and supervising Melinda Fittje, Researcher in Mass Spectrometry & Proteomics Core

Facility2009 – 2010 Training and supervising Muna Haddad, Technologist I in Mass Spectrometry & proteomics

Core Facility2003 – 2005 Co-mentor Yoshimi Enose, PhD, post-doctoral fellow2004 – 2007 Member, Graduate Student Comprehensive Exam Committee for departments other than PEN

(J. Gardner, H. Li, S. Deb, J. Porta)2005 – 2006 Co-mentor Mary Ricardo-Dukelow, MD, research fellow2005 – 2007 Mentor Wojciech Rozek, Ph.D., post-doctoral fellow2006 Mentor Sondra Holloway, Summer Undergraduate Student Research Program2006 – 2008 Member, PhD committee, Irena Kadiu, H.E. Gendelman, adviser2007 – 2009 Member, PhD committee, Sugato Banerjee, A. Ghorpade and H.E. Gendelman, co-advisors2006 – 2009 Member, PhD committee, Ashley Reynolds, H.E. Gendelman, advisor2006 – 2010 Member, PhD committee, Christopher Conley, R. MacDonald, advisor2006 – 2011 Member, PhD committee, Cameron Shweitzer, M. Belshan, advisor2007 – Present Member, PhD committee, Stephanie Kraft-Terry, H.E. Gendelman, adviser2007 Mentor, Adam Cornish, INBRE Undergraduate Summer Research Program2007 – 2008 Co-mentor, Adam Cornish, INBRE Undergraduate Research Program2008 Mentor, Julie Sawan Summer Undergraduate Student Research Program2009 Mentor, David Sanders Summer Undergraduate Student Research Program2009 – 2011 Mentor Gweanel Pottiez, Ph.D., post-doctoral fellow2010 Mentor, Daniel Podsiadlo Summer Undergraduate Student Research Program2010 – 2011 Training and supervising Stacy Wolfe, Technologist I in Mass Spectrometry & Proteomics

Core Facility2011 – 2012 Training and supervising Kelly Burnett, Technologist I in Mass Spectrometry & Proteomics

Core Facility2010 – 2013 Member, PhD committee, Amrita Datta Chaudhuri, H. Fox, adviser2010 – 2014 Mentor Nicole Haverland, Graduate Student, P. Ciborowski, adviser2010 – 2014 Member, PhD committee, Lance Villeneuve, H. Fox, advisor2010 – 2013 Member, PhD committee, Jessica Winkler, H. Fox, adviser2011 – 2015 Mentor Ariel Burns, Graduate Student, P. Ciborowski, adviser2011 – 2015 Member, PhD committee, Jason DeBoer, M. Belshan, adviser

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2011 – 2013 Mentor Pawel Olszowy, Ph.D., post-doctoral fellow2012 - 2015 Member, PhD committee, Yan Li, M. Belshan, adviser2012 – 2015 Member, PhD committee, Shawna Wollard, G. Kanmogne, adviser2012 Mentor, Shawn West, INBRE Undergraduate Summer Research Program2013 Mentor, Jiayi Yang (Jenny), Asia Pacific Rim Development Program student2014 Mentor, Bridget Mizener, Travis Lewis scholar, High school summer research program2014 – 2017 Member, PhD committee, Brendan Otteman, H. Fox, adviser2014 – 2016 Mentor, Kristin Reinsvold, Graduate Student MD/Ph.D, P. Ciborowski, adviser2014 – Present Member, PhD committee, Martha Ricaurte Chica, N. Schizas, adviser (UPR)2015 Mentor, Alexandra Bradley, Travis Lewis scholar, High school summer research program2015 Mentor, Emma Harwood, Undergraduate Summer Research Program

Textbooks:1. MR. Donelly, W. Rozek and P. Ciborowski. Proteomics and Genomics. In: Neuroimmune Pharmacology,

(H.E.Gendelman and T. Ikezu, eds.), Springer, Inc. 2015.2. G, Pottiez, J. Wiederin and P. Ciborowski. Metabolomics and Proteomics In: NeuroAIDS and Proteomics

and neuroAIDS diagnostics. In: The Neurology of AIDS, 3rd. ed, (H.E.Gendelman and T. Ikezu, eds.), Springer, Inc. 2010.

3. W. Rozek and P. Ciborowski. Bioinformatics – an overview. In: Proteomics and Metabolomics. [in Polish language] A. Kraj and J. Silberring (eds.) Editor: University of Warsaw, Poland, 2010.

4. W. Rozek and P. Ciborowski. Proteomics and Genomics. In: Neuroimmune Pharmacology, (H.E.Gendelman and T. Ikezu, eds.), Springer, Inc. 2008.

5. P. Ciborowski* and H. Ali. Bioinformatics In: Proteomics: Introduction to Methods and Applications. A. Kraj and J. Silberring (eds.) John Wiley & Sons, Inc., 2008. *- corresponding author.

Other UNMC Service:1. Edna Ittner Research Support Fund, Member of Review Panel in 2006.2. Annual Midwest Graduate Student Research Competition – judge (in 2004, 2005, 2008, 2010, 2011, 2012

and 2014).3. Graduate Studies Assistantship Review – UNMC study section member (in 2008, 2009, 2010, 2011, 2012

and 2014).4. Advisory Group in Pharmacogenomics to College of Pharmacy Curriculum Committee, member, 2009.

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