dan lindenmeyer, rph pharmacy mgr. - dillons. 6 main categories ◦ hypertension ◦...
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Dan Lindenmeyer, RPhPharmacy Mgr. - Dillons
6 main categories◦ Hypertension◦ Antidepressants◦ Pain meds◦ Cholesterol Reducers◦ Antibiotics◦ Antacids-Acid Reducers
Company has exclusive rights to market drug for 17 years after a patent has been approved◦ Most of the time patents are obtained while trials
are being run◦ By the time drug hits the market only 8 to 10
years are left on patent AB rated generics must be therapeutically
equal◦ The med must dissolve in the body at the same
rate and produce equivalent levels
Cardiology Hypertension Cholesterol reducers Antibiotics Diabetes Weight Loss Depression and Alzheimer’s Acid Reducers-antacids Herbal Supplements
Strong Narcotics◦ Percocet, Oxycontin, Percodan, Demerol
Mid-Level Narcotics◦ Lortab, Lorcet
Non-Narcotic Controlled◦ Darvocet
NSAIDS◦ Ibuprofen, naproxen, diclofenac, etodolac,
indomethacin, tramadol COX-II Inhibitors
◦ Celebrex◦ Mobic
Anti-arrhythmics Calcium Channel Blockers Ace Inhibitors Angiotensin receptor blockers Beta blockers Diuretics
Lanoxin---Antiarrhythmic
Pacerone—Antiarrhythmic
Mexilitine—Antiarrhythmic
Nitroglycerin—angina agent
Pressure on arterial walls ◦ Blood pressure meds work by blocking
receptors in arterial wall and relaxing the artery
◦ Diuretics remove fluids to decrease fluid volume of the body to lower blood pressure.
Beta blockers◦ Atenolol, metoprolol, propranolol
ACE Inhibitors◦ Lisinopril, enalapril, benazapril
Calcium channel blockers◦ Amlodipine, diltiazem
Angiotensin receptor blockers◦ Cozaar, Hyzaar, Micardis
Diuretics◦ Furosemide, triamterene/HCTZ,
hydrochlorothiazide
Previously d/c blood thinners 10 days before dental extraction or scaling and root planing
Rebound effect after antiplatelet interruption can result in stroke or MI
Minor surgical procedures can be carried out safely without altering antiplatelet therapy◦ Simple extractions <3 teeth
Additional visits for more than 3 teeth◦ Gingival surgery◦ Crowns and bridges◦ Scaling and surgical removal of teeth
Beta lactam antibiotics◦ Penicillins◦ Cephalosporins
Macrolide◦ Erythromycins◦ Zithromax
Quinolones◦ Levaquin◦ Ciprofloxacin
Sulfonamides Tetracyclines
Statins◦ No Generics
Lipitor Zetia Tricor Vytorin(combo of Zetia and Simvastatin)
◦ Generics Mevacor-Lovastatin Zocor-Simvastatin Pravachol-Pravastatin
Niacin
Injectable Insulins◦ Humalog--Novolog◦ Lantus◦ Humulin—N,R,U,70/30
Increase Insulins effect◦ Alcohol, anabolic steroids, beta blockers, MAO
inhibitors, tetracyclines, salicylates
Decrease Insulins effect◦ Oral contrceptives, corticosteroids, niacin,
smoking, thiazide diuretics, thyroid hormones
Metformin
Glyburide and glipizide
Glimepiride
Avandia
Actos
Phentermine
Xenical---Alli
Natural Supplements
How it works: Chemical in brain called serotonin is at higher cellular levels
Most antidepressants block re-uptake of serotonin to produce their effects
Very common condition
Tricyclic◦ Amitriptyline, nortryptyline, imipramine
Tetracyclic◦ Remeron
SSRI◦ Prozac, Zoloft, Lexapro, Celexa
SSRI & Norepinephrine◦ Effexor and Cymbalta
MAO-Inhibitors◦ Parnate, Nardil
H2 antagonists◦ Zantac◦ Tagamet Available OTC and Rx◦ Axid
PPI’s◦ Prevacid◦ Protonix ◦ Aciphex◦ Nexium◦ Prilosec –only one available as an OTC
Namenda
Aricept
Non-Sedating◦ Zyrtec◦ Allegra◦ Clarinex◦ Claritin—OTC
OTC◦ Benadryl◦ Chlorpheniramine◦ Clemastine
Not regulated by FDA◦ No proof of effectiveness◦ Take at own risk◦ Products have been proven safe at
recommended doses Very popular alternative to getting
prescriptions
Resources:◦ Drug information handbook for dentistry-7th
Edition◦ Clinical pharmacology