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CURRICULUM VITAE 11/4/20 Name: Neal L. Weintraub, M.D. MCG Rank(s): Professor of Medicine MCG Title(s): Kupperman Eminent Scholar in Cardiovascular Medicine Office Address:1120 15th Street, CB 3330 Office Telephone: 706-721-6164 Home Address: 2908 Lombardy Court, Augusta, GA 30909 Home Telephone: 706-755-9185 EDUCATION

High School

8/1973-6/1977 Westover High School, Albany GA College (Undergraduate)

8/1977-6/1980 Tulane University, Biology major, no degree Graduate and Professional

8/1980-6/1984 Tulane University, M.D. Degree

Post-Doctoral Training 7/1984-6/1986 Internal Medicine Resident (PGY-1 & 2) Emory

University 7/1986-6/1987 Internal Medicine Resident (PGY-3) University of

Illinois, Urbana-Champaign, Illinois 7/1991-7/1995 Fellow Cardiovascular Diseases, Saint Louis

University 7/1992-6/1994 Postdoctoral Research Fellow, National Research

Service Award, Clinical Pharmacology, Saint Louis University

Board Certification American Board of Internal Medicine, 1987

American Board of Cardiovascular Diseases ,1995; recertified in 2005 and in 2015

Licensure Missouri 3/13/91-1/31/96

Iowa 10/6/95-6/1/07 Ohio 6/30/06-6/30/2013 Georgia 4/05/13-present

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PROFESSIONAL Academic Appointments 7/1987-6/1988 Clinical Instructor of Medicine, University of Illinois College

of Medicine, Urbana-Champaign, Illinois 7/1987-6/1990 Staff Physician, VA Medical Center, Danville, Illinois 7/1988-6/1990 Assistant Clinical Professor of Medicine, University of

Illinois College of Medicine, Urbana-Champaign, Illinois 7/1990-6/1991 Staff Physician, VA Medical Center, St. Louis, Missouri 7/1990-6/1991 Assistant Professor of Clinical Medicine, St. Louis

University 8/1995-6/2006 Staff Physician, VA Medical Center, Iowa City, IA 8/1995-6/1996 Associate, Cardiology Division, University of Iowa College

of Medicine, Iowa City, Iowa 7/1996-6/2001 Assistant Professor of Medicine, Cardiology Division University of Iowa College of Medicine, Iowa City, Iowa 7/2001-6/2005 Associate Professor of Medicine (with tenure), Cardiology

Division University of Iowa College of Medicine, Iowa City, Iowa

7/2002-6/2005 Associate Professor, Free Radical and Radiation Biology Graduate Program with the Department of Radiation Oncology, University of Iowa College of Medicine, Iowa City, Iowa

7/2003-6/2005 Interim Director, Cardiology Division, University of Iowa College of Medicine

7/2005-6/2006 Professor of Medicine (with tenure), Cardiology Division, University of Iowa College of Medicine, Iowa City, Iowa

7/2005-6/2006 Professor, Free Radical and Radiation Biology Graduate Program with the Department of Radiation Oncology, University of Iowa College of Medicine, Iowa City, Iowa

7/2005-5/2006 Medical Director, UI Heart Care, University of Iowa College of Medicine

6/2006-6/2013 Stonehill Professor of Medicine (with tenure) and Director, Cardiovascular Division, University of Cincinnati College of Medicine, Cincinnati, Ohio

7/2008-6/2013 Co-director, Cardiovascular Center of Excellence, University of Cincinnati College of Medicine

6/2013-Present Professor of Medicine (with tenure), Kupperman Eminent Scholar in Cardiovascular Medicine, Augusta University

6/2013-Present Associate Director, Vascular Biology Center, Augusta University

7/2014-2/2017, Interim Chief, Division of Cardiology 12/2019-present Chief, Division of Cardiology Administrative Responsibilities/Appointments (i.e., Editorial Boards, Professional Societies, List positions and dates)

Editorial Board:

1999-2006: American Journal of Physiology Heart and Circulatory Physiology

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1999-present: Arteriosclerosis, Thrombosis and Vascular Biology 2006-2008: Journal of the CardioMetabolic Syndrome 2014-present: Associate Editor, Translational Research 2017-2018: World J Cardiology 2017: Guest Editor, Intern J Mol Sci, Special Issue “Oxidative Stress in Vascular Diseases” 2018-present: Editorial board, Cardiovascular Research 2018-present: Review Editor, Frontiers in Physiology (Integrative Physiology) 2019-present: Review Editor, Frontiers in Cardiovascular Medicine (Cardio-Oncology)

Reviewer (manuscripts): Circulation Research

Am J Physiol Arteriosclerosis, Thrombosis and Vascular Biology Cardiovascular Research Circulation Lipids JPET Hypertension Nature J Am Coll Cardiol J Am Heart Assoc Science Transl Med Comprehensive Physiol

Reviewer (abstracts) American Heart Association American College of Cardiology Central Society for Clinical Research Study Sections, Grant Reviewer: 1999 Ad Hoc reviewer of VA Merit Review grants

1999 NIH ALTX4 4/2001-3/2002 AHA GRA-3B 5/2001 NIH PPG review (Ruderman PPG) 7/2001 NIH CCVS 2/2002 NIH CVB 3/2002-2003 AHA CV Regulation II 2003-2005 NIH VCMB 2004-2005 VA Merit Cardiovascular Studies B 2006 NIH AICS (temporary member) 2008-2013 NIH AICS (charter member) 2011-2013 NIH AICS (Chair) 2014 NIH Special Emphasis Panel 2014 VA Cardiovascular Studies B 2014 NIH AICS 2015 NIH Cardiovascular SBIR/STTR 2016 NIH Special Emphasis Panel 2016 NIH AICS

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2016 NIH CICS 2017 NIH CICS 2017 NIH VCMB 2018 NIH CICS 2018 NASA Space Radiation-Cardiovasc. Panel 2018 NIH Cardiovascular SBIR/STTR (Chair) 2018 NIH CICS 2019 NIH Cardiovascular SBIR/STTR (Chair) 2019 NIH Special Emphasis Panel 2019 NIH Cardiovascular SBIR/STTR (Chair) 2020 NIH Cardiovascular SBIR/STTR (Chair) 2020 NIH CICS

Committee Assignments/Service State/National Committees

2009-2011 Chair, Ohio Mission:Lifeline Public Education Workgroup, American Heart Association

2010-2011 Chair, American Heart Association Writing Committee on emergent management of acute decompensated heart failure

2016-2017 Member, Mid-Atlantic Affiliate Heart & Stroke Quality Summit Planning Committee

Other 2008-2009 PPG External Oversight Committee, Mechanisms

of Abdominal Aortic Aneurysm Formation, HL080100, PI Alan Daugherty, University of Kentucky

Local 1987-90 Resident Recruitment Committee, University of

Illinois College of Medicine 1997 Ad hoc committee member for faculty recruitment,

Department of Internal Medicine 1999 Committee member for resident recruit/resident life,

Department of Internal Medicine 1999 Chairman, ADS work group, Department of Internal

Medicine 2000 Committee Member, Basic Research Future

Planning Group, Department of Medicine 2000 Committee Member, Pilot Intramural Grants

Programs Committee,College of Medicine 2001-06 College of Medicine Research Committee 2002-04 Department of Internal Medicine Promotions

Committee; 2002-06 UIHC Pharmacy and Therapeutics Committee 2004 New Clinical Initiatives Committee, UIHC 2005 Opthalmology Chair Search Committee 2011 Co-chair Strategic Planning Committee for UC

Cardiovascular Institute 2013 Member, MCG Strategic Plan Research Workgroup

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2013 Otolaryngology Chair Search Committee 2013- Vascular Biology Center Search Committee 2013-18 Member, IRB-A, Georgia Regents University 2014- Promotions and Tenure Committee, Department of

Medicine 2014- Mentor, Faculty Mentoring Program, Department of

Medicine 2015- Member, Admissions Committee, Medical College

of Georgia MD/PhD program 2015-18 Chair, Pulmonary Division Chief Recruitment

Committee 2016- Mentor, Leadership Through Ethics Program,

Medical College of Georgia 2017 Member, Gastroenterology Division Chief

Recruitment Committee 2017-18 Member, Cardiothoracic Surgery Chief Recruitment

Committee 2018 Member, Department of Internal Medicine Chair

Recruitment Committee 2018 Chair, Department of Physiology Chair Recruitment

Committee 2019 Chair, Department of Neuroscience and

Regenerative Medicine Chair Recruitment Committee

Research and Training Grants Awarded

Teva protocol CEP-41750 (Weintraub site PI) 3/12/15-6/1/20 Teva Pharmaceutical Industries A Double-blind, Randomized, Sham-procedure-controlled, Parallel-group Efficacy and Safety Study of Allogeneic Mesenchymal Precursor Cells (CEP-41750) in Patients With Chronic Heart Failure Due to Left Ventricular Systolic Dysfunction of Either Ischemic or Nonischemic Etiology R01AR070029 (Weintraub co-PI) 04/01/2016 – 03/31/2021 NIH/NIAMS (Tang contact PI) “Innovative Approaches to Treat Duchenne Muscular Dystrophy Using iPSC-Derived Muscle Progenitors.” Major Goal(s): The proposed studies will develop novel stem cell approaches to treating Duchenne muscular dystrophy. R01HL134354-01 (Weintraub co-PI) 07/01/2016 – 06/30/2021 NIH/NHLBI (Tang contact PI) “Notch1/miR-322 Axis in Stem Cell Mediated Vascular Repair” Major Goal(s): To investigate how Notch-1 and the newly identified Notch-1 target miR-322 sustain and potentiate the beneficial effects of HP on the vascular cell survival and angiogenic activity of stem cells and determine whether harnessing these regulatory mechanisms in stem cells can enhance vessel protection and repair in a mouse model of myocardial infarction (MI).

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R01HL086555-08A1 (Weintraub co-I) 05/01/2016 – 03/31/2020 NIH/NHLBI (Tang PI) “Hypoxia and cardiac stem cell homing” Major goals: The proposed experiments will address critical gaps in our understanding of the roles of chromatin accessibility in stem cell responses to hypoxia, and key stem cell functions in angiogenesis and tissue repair in the elderly. This is an in-depth study to investigate the role of epigenetic remodeling in regulating the function of aged stem cells. R01HL126949 (Weintraub PI) 03/01/2016 – 02/28/2020 NIH/NHLBI “Epigenetic regulation of HDAC9 in obesity and atherosclerosis” Major Goal(s): The proposed studies will provide insight into the role of HDAC9 in adipose tissue biology and atherosclerosis and may also form the basis for development of selective HDAC9 blocking agents to counter DIO. R01HL142097 (Weintraub PI) 05/01/2018-04/30/22 NIH/NHLBI “Mechanisms of myeloperoxidase and Nox4 interactions in abdominal aortic aneurysm” Major Goal(s): We will test the hypothesis that myeloperoxidase cooperates with Nox4 to promote deleterious oxidative stress in abdominal aortic aneurysms, which can be therapeutically modulated by targeting PGD2 receptors and GPR109A. R56AG064895 (MPI: Lu/Weintraub) 09/15/2019 – 06/30/2021 NIH/NIA “HDAC9, aging and Alzheimer’s Disease” Major Goal (s): The purpose of this application is to investigate the role of HDAC9 in the brain and in peripheral adipose tissues in the pathogenesis of age-related cognitive impairment. Role: Co-Principal Investigator R01HL147639 (Weintraub Co-I, Belin PI) 01/01/20-12/31/23 “Leptin in HIV-associated vascular diseases” Major goal(s): identify the molecular mechanisms whereby HIV and cART regulate adiposity and atherogenesis to identify new therapeutic avenue for the prevention and treatment of CVD- associated with HIV. R01HL112640 (Weintraub PI) 07/13/12-11/30/17 NIH/NHLBI “Perivascular adipose tissue and vascular remodeling”. The purpose of this study is to determine the role of fat that surrounds blood vessels (also known as perivascular adipose tissue, or PVAT) in causing vascular disease.

R01DK074932 (Weintraub Co-I) 2/5/11-1/31/16

NIDDK (Hui PI)

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“LDL Receptor Related Protein-1 in Metabolic and Cardiovascular Disease Modulation.” The goal of this project is to test the overall hypothesis that LRP1 suppresses diet-induced tissue dysfunctions and inflammation and protects against injury-induced steatohepatitis via modulation of lysosomal enzyme sorting and receptor cell signaling events.

R01HL076684 (Weintraub PI) 2/01/10 – 1/31/14

NHLBI “Antigotensin II, Oxidative Stress and Aneurysm Formation.” The major goal of this project is to investigate the role of oxidative stress in abdominal aortic aneurysm formation.

R01HL061446 ( Weintraub Co-I) 7/1/10-6/30/14

NHLBI (Sigmund PI) “Significance of Angiotensinogen Variance in Hypertension.” The long term objective of this project is to identify mechanisms of angiotensinogen gene expression in adipose tissue and how this relates to susceptibility to hypertension.

Baxter Protocol (Weintraub site PI) 9/04/12 – 6/01/13

Baxter Healthcare “A prospective, randomized, double-blinded, active-controlled and unblinded standard of care, (SOC) controlled study to determine the efficacy and safety of targeted intramyocardial, delivery of G-CSF mobilized autologous CD34+ cells for the improvement in total exercise time during standardized exercise testing in subjects with refractory angina pectoris and chronic myocardial ischemia (CMI)”. The objective of this study is to assess the efficacy of autologous stem cells injected into the heart to alleviate myocardial ischemia. U01059 (Weintraub PI) 7/1/10 -06/30/11

NIH, Center for Clinical and Translational Science and Training “Using topical capsaicin to limit reperfusion injury.” The purpose of this application is to determine the feasibility of cutaneous TRPV1 channel activation with capsaicin as a potential therapeutic approach to limiting myocardial reperfusion injury in humans.

TECH-07-024 (Weintraub/Jones Co-PI) 11/1/09-4/30/11 Ohio Dept of Dev./Cleveland Clinic Foundation Global Cardiovascular Innovation Center. “Development of CardioPatch for acute MI.” Subcontracted from CardioCeption, LLC. The goal of this project is to advance our work in remote, cutaneous cardioprotection in mice into a pig model of myocardial infarction.

P01 HL014388 (Weintraub Co-I) 7/15/08 – 6/30/13

NHLBI (Abboud PI) “Integrative Neurobiology of Cardiovascular Regulation.” The major goal of this project is to understand the integrative role of adipocytes in hypertension.

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AARG Award (Weintraub PI) 1/1/07-7/1/08 Pfizer Pharmaceuticals “Effects of Atorvastatin on Pro-inflammatory Activity in Human Epicardial Adipocytes.” The goal of this project is to determine the modulatory effects of atorvastatin on inflammatory responses in epicardial adipocytes and how this may influence atherosclerosis. 10. Baxter Protocol (Weintraub Site PI) 12/1/06- 7/1/08 Baxter Healthcare “A double-blind, prospective, randomized, placebo-controlled study to determine the tolerability, efficacy, safety, and dose range of intramyocardial injections of G-CSF mobilized Auto-CD34+ cells for reduction of angina episodes in patients with refractory chronic myocardial ischemia.” The objective of this study is to assess the safety and efficacy of autologous stem cells injected into the heart to alleviate myocardial ischemia. P01 HL062984 (Weintraub Leader Proj.2) 4/1/06 – 3/31/11 NHLBI (Heistad PI) “Vascular Mechanism in Atherogenesis: CD14, Surfactant Proteins, and Vascular Inflammation.” The major role of this project is to determine the role of CD14 and surfactant proteins in the modulating vascular inflammation and atherosclerosis. R01HL076684 (Weintraub PI) 2/10/05 – 1/31/10

NHLBI “Antigotensin II, Oxidative Stress and Aneurysm Formation.” The major goal of this project is to investigate the role of oxidative stress in abdominal aortic aneurysm formation. VA Merit Review (Weintraub PI) 10/1/04-6/30/05 “Oxidative Stress in Abdominal Aortic Aneurysm Formation.” The goal of this project (terminated due to overlap with NIH grant) is to investigate the role of oxidative stress in abdominal aortic aneurysm American Heart Association Grant in Aid 1/1/04-12/31/05 (Weintraub Co-I) “Human Cytomegalovirus Infection in Blood Vessels.” The goal of this project is to investigate the mechanisms whereby cytomegalovirus infects human blood vessels in the setting of atherosclerosis. University of Iowa GCRC (Weintraub PI) 1/1/04-6/30/06 “Oxidative Stress in Aortic Aneurysm.” The purpose of this project is to commence translating the basic science research on aneurysms into human subjects. RO1HL70860 (Weintraub PI) 5/1/03-4/30/08

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NHLBI “Endotoxin, Vascular Inflammation, and Atherosclerosis.” The long-term objective of this project is to investigate the pro-inflammatory effects of endotoxin in human blood vessels and in cultured human vascular cells. P01 HL062984 (Weintraub Leader Proj.3) 6/1/00-5/31/06 NHLBI (Heistad PI) “Vascular Mechanism in Atherogenesis: Role of Reactive Oxygen Species in Smooth Muscle Growth and Viability.” The major role of this project is to determine the role of reactive oxygen species in regulating growth and viability of smooth muscle cells in vascular disease. VA Merit Review (Weintraub Co-I) 4/1/2000-9/30/2004 (PI: Dellsperger) Mechanisms of Coronary Microvascular Regulation. The goal of this project is to determine the mechanisms whereby eicosanoid metabolites of arachidonic acid regulate the coronary microcirculation. P01 HL49264 (Weintraub Leader Proj.4) 9/30/97-9/29/02 NHLBI (Spector PI) “Fatty Acids, Lipoproteins, and Lipid Oxidation: Epoxyeicosatrienoic Acids in the Coronary Circulation.” The purpose of this project is to determine the mechanisms whereby epoxyeicosanoic acid is metabolized by, and incorporated into, coronary arteries, and how this affects arterial function. American Heart Association Clinician-Scientist Award 7/1/96-6/30/01 (Weintraub PI). “Participation of Arachidonic Acid in Endothelium-Mediated Regulation of the Coronary Circulation”. The goal of this project is to support career development while delineating the mechanisms whereby arachidonic acid metabolites regulate the coronary circulation. American Heart Association Grant-in-Aid (Weintraub PI) 7/1/96-9/1/96 “Identification of Endothelium-derived Hyperpolarizing Factor in Porcine Coronary Artery.” The purpose of this project (terminated due to overlap with NIH grant) is to determine the mechanisms whereby epoxyeicosanoic acid is metabolized by, and incorporated into, coronary arteries, and how this affects arterial function.

AWARDS/HONORS 1977-1978 University Scholars Program, Tulane University 1977-1979 Freshman Honor Premedical Society, Tulane

University 1983 Alpha Omega Alpha, Tulane University 1986-1987 Resident of the Year Award, University of Illinois

College of Medicine, Urbana-Champaign

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1987-1988 Raymond B. Allen Instructorship (Golden Apple Teaching Award), University of Illinois College of Medicine

1988-1989 Raymond B. Allen Instructorship (Golden Apple Teaching Award), University of Illinois College of Medicine

1991-1992 Cardiovascular Fellow of the Year Award, Saint Louis University School of Medicine

1994 American College of Cardiology/Bristol-Myers Squibb Affiliate Travel Award, Atlanta, GA

1994-1995 Affiliate-in-Training Representative, Am. Coll. Of Cardiology

1995 Senior Fellow Achievement Award, Cardiology Division, St. Louis University School of Medicine

2002, 2004, 2005 Above and Beyond Award, University of Iowa Hospitals and Clinics

2007-2013 “Best Doctors in America” 2007-2013 “Cincinnati’s Best Doctors” 2013- GRA Herbert S. Kupperman M.D. Eminent Scholar

in Cardiovascular Medicine 2015 Distinguished Faculty Award for Basic Science

Research, Medical College of Georgia 2020 Professionalism Award, Medical College of Georgia 2020 A. Ross McIntyre Award for Advancements in

Medical Science, University of Nebraska Department of Physiology

SCIENTIFIC AND PROFESSIONAL SOCIETIES

National Societies:

1991-present American College of Cardiology 1997-present Central Society for Clinical Research 1998-present American Physiologic Society 1998-present American Heart Association, Council on Arteriosclerosis, Thrombosis, and Vascular Biology 1998-present Fellow, American College of Cardiology 1999-2002 Fellow, American Heart Association Council on

High Blood Pressure Research 2000-2003 Member, American Federation for Medical

Research 2007-2009 Councilor, Central Society for Clinical Research 2009-2010 Vice President, Central Society for Clinical

Research 2010-2011 President Elect, Central Society for Clinical

Research 2012-2013 President, Central Society for Clinical Research

Local Societies:

1994-1995 Missouri Chapter of ACC, Affiliate-in-Training representative

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PRESENTATIONS AT NATIONAL, REGIONAL AND STATE MEETINGS (Last Five Years)

Weintraub, N.L.: “Epigenetic regulation of vascular disease.” Invited speaker, AHA National Meeting, Chicago, IL, November 2018. Weintraub, N.L.: “Partners in crime: myeloperoxidase and Nox4 in abdominal aortic aneurysm,” Southeast Lipid Research Conference, Cincinnati, OH, September 2019. Weintraub, N.L.: “Adipose Tissue and Vascular Perturbation/Atherosclerosis”. Invited speaker, AHA National Meeting, Philadelphia, PA., November 2019.

MEETINGS, VISITING PROFESSORSHIPS, etc. (Last Five Years)

Weintraub, N.L.: “Turning atherosclerosis inside out: role of perivascular adipose tissue.” Invited talk, University of Virginia Division of Cardiology, Charlottesville, VA, May, 2015. Weintraub, N.L.: “Contemporary management of aortic diseases.” Annual Grolman Lecture, University of Virginia Department of Internal Medicine (Medical Grand Rounds), Charlottesville, VA, May, 2015. Weintraub, N.L.: “Role of histone deacetylase-9 in adipocyte differentiation and diet-induced obesity”. Invited talk, Massachusetts General Hospital/Harvard Medical School Cardiovascular Center, Boston, MA, May, 2015. Weintraub, N.L.: “Role of oxidative stress in the pathogenesis of abdominal aortic aneurysms: therapeutic implications.” Invited talk, University of Georgia Physiology/Pharmacology Department, Athens, GA, November, 2015. Weintraub, N.L.: Invited speaker, “Heart Disease & Diabetes: Innovations for Prevention,” Health Connect South annual conference, Atlanta, GA, September 2016. Weintraub, N.L.: “HDAC9, a promising target in obesity-related cardiometabolic disease.” Invited talk, Medical College of Wisconsin Cardiovascular Center, Milwaukee, WI, August 2017. Weintraub, N.L.: “Role of oxidative stress in the pathogenesis of abdominal aortic aneurysm: therapeutic implications.” Invited talk, Loyola University School of Medicine Department of Pharmacology and Molecular Therapeutics, June 2018.

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Weintraub, N.L.: “HDAC9, a promising target in obesity-related cardiometabolic disease.” Invited talk, Yale University School of Medicine Cardiovascular Center, June 2018. Weintraub, N.L.: “Systemic role of perivascular vascular tissue (PVAT) in vascular disease.” Invited talk, Shanghai, China September 2018. Weintraub, N.L.: “Learning from one’s mistakes: the quest to understand abdominal aortic aneurysms.” Invited talk, Department of Internal Medicine Research Seminar, University of Toledo, April 2019. Weintraub, N.L.: “Contemporary management of aortic diseases.” Invited talk, Department of Internal Medicine Grand Rounds, University of Toledo, April 2019. Weintraub, N.L.: “Partners in crime: myeloperoxidase and Nox4 in abdominal aortic aneurysm.” Endowed lecture given in conjunction with receiving the A. Ross McIntyre Award, Department of Physiology, University of Nebraska, March 2020.

PUBLICATIONS IN REFEREED JOURNALS

* = Carried out most experimental protocols, wrote first complete draft of manuscript # = Collaborated in experimental studies, helped write the manuscript + = Guided and coordinated the project, provided key scientific input/direction, oversaw the completion of the manuscript ^ = Participated in clinical studies and/or writing committee leading to publication of the manuscript.

1. Weintraub, N.L. and Chaitman, B.R.: Newer concepts in the medical management of patients with congestive heart failure. Clin. Cardiol. 16:380-390, 1993.*

2. Weintraub, N., Dolan, G., and Stratmann, H.: Hemodynamic and respiratory responses to maximal treadmill and arm ergometry in men with chronic obstructive pulmonary disease. Journal of Cardiopulmonary Rehabilitation 13:25-30, 1993.*

3. Weintraub, N.L., Joshi, S.N., Branch, C.A., Stephenson, A.H., Sprague, R.S., and Lonigro, A.J.: Relaxation of porcine coronary artery to bradykinin: Role of arachidonic acid. Hypertension 23:976-981, 1994.*

4. Lonigro, A.J., Weintraub, N.L., Branch, C.A., Stephenson, A.H., McMurdo, L., and Sprague, R.S.: Endothelium-dependent relaxation to arachidonic acid in porcine coronary artery: Is there a fourth pathway? Polish J. Pharmacol. 46:567-577, 1994.*

5. Sprague, R.S., Stephenson, A.H., Dimmitt, R.A., Weintraub, N.L., Branch, C.A., McMurdo, L., and Lonigro, A.J.: Inhibition of nitric oxide synthesis results in a selective increase in arterial resistance in rabbit lungs. Polish J. Pharmacol. 46:579-585, 1994.#

6. Sprague, R.S., Stephenson, A.H., Dimmitt, R.A., Weintraub, N.L., Branch, C.A., McMurdo, L., Lonigro, A.J.and Weintraub, N.A.: Effect of L-NAME on pressure-

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flow relationships in isolated rabbit lungs: Role of red blood cells. Am. J. Physiol. 269(Heart Circ. Physiol. 38):H1941-H1948, 1995.#

7. Weintraub, N.L., Stephenson, A.H., Sprague, R.S., McMurdo, L., and Lonigro, A.J.: Relationship of arachidonic acid release to porcine coronary artery relaxation. Hypertension 26:684-690, 1995.*

8. Stephenson, A.H., Sprague, R.S., Weintraub, N.L., McMurdo, L., and Lonigro, A.J.: Inhibition of cytochrome P-450 attenuates the hypoxemia of acute lung injury in dogs. Am. J. Physiol. 270(Heart Circ. Physiol.): H1355-H1362, 1996.#

9. Lonigro, A.J., McMurdo, L., Stephenson, A.H., Sprague, R.S., and Weintraub, N.L.: Hypotheses regarding the role of pericytes in regulating movement of fluid, nutrients and hormones across the microcirculatory endothelial barrier. Diabetes 45(Suppl. 1):S38-S43, 1996.#

10. Fang, X., Kaduce, T.L., Weintraub, N.L., VanRollins, M., and Spector, A.A.: Function implications of a newly-characterized pathway of 11,12-epoxyeicosatrienoic acid metabolism in arterial smooth muscle. Circ. Res. 79:784-793, 1996.#

11. Fang, X., Kaduce, T.L., Weintraub, N.L., and Spector, A.A.: Cytochrome P450 metabolites of arachidonic acid: Rapid incorporation and hydration of 14,15-epoxyeicosatrienoic acid in arterial smooth muscle cells. Prostaglandins, Leukotrienes, and Essential Fatty Acids 57:367-371, 1997.#

12. Weintraub, N.L., Fang, X., Kaduce, T.L., VanRollins, M., Chatterjee, P., and Spector, A.A.: Potentiation of endothelium-dependent relaxation by epoxyeicosatrienoic acids. Circ. Res. 81:258-267, 1997.*

13. Widmann, M.D., Weintraub, N.L., Brooks, L.A., and Dellsperger, K.C.: Cytochrome P-450 pathway in acetylcholine-induced canine coronary microvascular vasodilation in vivo. Am. J. Physiol. (Heart Circ. Physiol.)274:H283-H289, 1998.#

14. Fang, X., Weintraub, N.L., Rios, C.D., Chappell, D.A., Zwacka, R.A., Engelhardt, J.F., Oberley, L.W., Yan, T., Heistad, D.D., and Spector, A.A.: Overexpression of human superoxide dismutase inhibits oxidation of low-density lipoprotein by endothelial cells. Circ. Res. 82:1289-1297, 1998.+

15. Oltman, C.L., Weintraub, N.L., VanRollins, M., and Dellsperger, K.C.: Epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids are potent vasodilators in the canine coronary microcirculation. Circ. Res. 83:932-939, 1998.#

16. Fang, X., Moore S.A., Stoll, L.L., Rich, G., Kaduce, T.L., Weintraub, N.L., and Spector, A.A.: 14,15-Epoxyeicosatrienoic acid inhibits prostaglandin E2 production in vascular smooth muscle cells. Am. J. Physiol. 275(Heart Circ. Physiol. 44):H2113-H2121, 1998.#

17. Pesek, C.A., Cooley, R., Narkiewicz, K., Dyken, M., Weintraub, N.L., and Somers V.: Theophylline therapy for near-fatal Cheyne-Stokes respiration. A case report. Ann. Int. Med. 130:427-30, 1999.#

18. Lee, H.L., Lu, T., Weintraub, N.L., VanRollins, M., Spector, A.A., and Shibata, E.F.: Effects of epoxyeicosatrienoic acids on the cardiac sodium channels in isolated rat ventricular myocytes. J. Physiol. (London) 519:153-168, 1999.#

19. Brown, M.R., Miller, Jr., F.J., Li, W.G., Ellingson, A.N., Mozena, J.D., Chatterjee, P., Engelhardt, J.F., Zwacka, R.M., Oberley, L.W., Spector, A.A., and Weintraub, N.L.: Overexpression of human catalase inhibits proliferation and promotes apoptosis in vascular smooth muscle cells. Circ. Res. 85:524-533, 1999.+

20. Weintraub, N.L., Fang, X., Kaduce, T.L., VanRollins, M., Chatterjee, P., and Spector, A.A.: Epoxide hydrolases regulate epoxyeicosatrienoic acid

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incorporation into coronary endothelial phospholipids. Am. J. Physiol. (Heart Circ. Physiol.)277:H2098-H2108, 1999.*

21. Fang, X., Weintraub, N.L., Stoll, L.L., Kaduce, T.L., and Spector, A.A.: Epoxyeicosatrienoic acids increase intracellular calcium concentration in vascular smooth muscle cells. Hypertension 34:1242-1246, 1999.#

22. Fang, X., Kaduce, T.L., VanRollins, M., Weintraub, N.L., and Spector, A.A.: Conversion of epoxyeicosatrienoic acids (EETs) to chain-shortened epoxy fatty acids by human skin fibroblasts. J. Lipid Res. 41:66-74, 2000.#

23. Li, W.G., Miller Jr., F.J., Brown, M.R., Ayslworth, G.R., Spector, A.A., Oberley, L.W., and Weintraub, N.L.: Enhanced H2O2-induced cytotoxicity in "epithelioid" smooth muscle cells: Implications for neointimal regression. Arterioscler. Thromb. Vasc. Biol. 20:1473-1479, 2000.+

24. Fang, X., Moore, S.A., Weintraub, N.L., Oberley, L.W., Synder, G.D., Spector, A.A.: Induction of cyclooxygenase-2 by overexpression of human catalase gene in cerebral microvascular endothelial cells. J. Neurochem. 75:614-623, 2000.#

25. Zink, M.H., Oltman, C., Lu, T., Katakam, P.V.G., Kaduce, T.L., Lee, H.C., Dellsperger, K.C., Spector, A.A., Myers, P.R., and Weintraub, N.L.: 12-Lipoxygenase in the porcine coronary microcirculation: Implications for coronary vasoregulation. Am. J. Physiol. (Heart & Circ. Physiol.) 280:H693-H704, 2001.+

26. Fang, X., Kaduce, T.L., Weintraub, N.L., Harmon, S., Teesch, L,M., Morisseau, C., Thompson, D.A., Hammock, B.D., and Spector, A.A.: Pathways of epoxyeicosatrienoic acid metabolism in endothelial cells: Implications for the vascular effects of soluble epoxide hydrolase inhibition. J. Biol. Chem. 276:14867-14874, 2001.#

27. Faraci, F.M., Sobey, C.G., Chrissobolis, S., Lund, D.D., Heistad, D.D., and Weintraub N.L.: Arachidonate dilates the basilar artery by a lipoxygenase-dependent mechanism and activation of K+ channels. Am. J. Physiol. (Regulatory Physiology) 281:R246-R253, 2001.+

28. Lu, T., Katakam, P.V.G., VanRollins, M., Weintraub, N.L., Spector, A.A., and Lee, H.C.: Dihydroxyeicosatrienoic acids are potent activators of Ca2+-activated K+ channels in isolated coronary arterial myocytes. J. Physiol. (London) 534:651-667, 2001.#

29. Li, W.G., Miller Jr., F.J., Zhang, H.J., Spitz, D.R., Oberley, L.W., and Weintraub, N.L.: H2O2-induced O2

.- production by a non-phagocytic NAD(P)H oxidase causes oxidant injury. J. Biol. Chem. 276:29251-29256, 2001.+

30. Oltman, C.L., Kane, N.L., Fudge, J.L., Weintraub, N.L., and Dellsperger, K.C.: Endothelium-derived hyperpolarizing factor in coronary microcirculation: Responses to arachidonic acid. Am. J. Physiol. (Heart Circ. Physiol.) (Heart Circ. Physiol.) 281:H1553-H1560, 2001.#

31. Lu, T., Weintraub, N.L., Spector, A.A., and Lee, H.C.: Activation of ATP-sensitive K+ channels by epoxyeicosatrienoic acids in rat cardiac ventricular myocytes. J. Physiol. (London) 537:811-827, 2001.#

32. Shihabi, A, Li, W.G., Miller Jr., F.J., and Weintraub, N.L.: Antioxidant therapy for atherosclerotic vascular disease: The promise and the pitfalls. Am. J. Physiol. (Heart Circ. Physiol.)282:H797-H802, 2002.+

33. Weintraub, N.L.: The Nox response to injury (Editorial). Arterioscler. Thromb. Vasc. Biol. 22:4-5,2002.*

34. Miller, Jr., F.J., Sharp, W.J. Fang, X., Oberley, L.W., Oberley, T.D., and Weintraub, N.L.: Oxidative stress in human abdominal aortic aneurysms: A potential mediator of aneurysmal remodeling. Arterioscler. Thromb. Vasc. Biol. 22:560-565, 2002.+

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35. Fang, X., Weintraub, N.L., Oltman, C.L., Stoll, L., Kaduce, T.L., Harmon, S., Dellsperger, K.C., Morisseau, C., Hammock, B.D., and Spector, A.A.: Human coronary endothelial cells convert 14,15-EET to a biologically active chain-shortened epoxide. Am. J. Physiol. (Heart Circ. Physiol.)283:H2306-H2314, 2002.#

36. Miller, A.W., Katakam, P.V.G., Lee, H.C., Tulbert, C.D., Busija, D.W., and Weintraub, N.L.: Arachidonic acid-induced vasodilation of rat small mesenteric arteries is lipoxygenase-dependent. J. Pharm. Exp. Ther. 304:139-144, 2003.+

37. Li, W.G., Stoll, L.L., Rice, J.B., Xu, S.P., Miller Jr., F.J., Chatterjee, P., Hu, L., Oberley, L.W., Spector, A.A., and Weintraub, N.L.: Activation of NAD(P)H oxidase by lipid hydroperoxides: Mechanism of oxidant-mediated smooth muscle cytotoxicity. Free Rad. Biol. Med. 34:937-946, 2003.+

38. Weintraub, N.L.: Impaired hypoxic coronary vasodilation and ATP-sensitive potassium channel function. A manifestation of diabetic microangiopathy in humans? (Editorial). Circ. Res. 92:127-129, 2003.*

39. Fang, X., Weintraub, N.L., and Spector, A.A.: Differences in positional esterification of 14,15-epoxyeicosatrienoic acid in phosphatidylcholine of porcine coronary artery endothelial and smooth muscle cells. Prostag. Oth. Lipid M. 71:33-42, 2003.#

40. He, T., Weintraub, N.L., Goswami, P.C., Chatterjee, P., Domann, F.E., and Oberley, L.W: Redox factor-1 contributes to the regulation of progression from G0/G1 to S by platelet derived growth factor in vascular smooth muscle cells. Am. J. Physiol. (Heart Circ. Physiol.)285:H804-H812, 2003.#

41. Rice, J.B., Stoll, L.L., Li, W.G., Denning, G.M., Weydert, J., Charipar, E., Richenbacher, W.E., Miller, F.J. Jr., and Weintraub, N.L.: Low level endotoxin induces potent inflammatory activation of human blood vessels: Inhibition by statins. Arterioscler. Thromb. Vasc. Biol. 23:1576-1582, 2003.+

42. Oltman, C.L., Kane, N.L., Miller Jr., F.J., Spector, A.A., Weintraub, N.L, and Dellsperger, K.C.: Reactive oxygen species mediate arachidonic acid-induced dilation in porcine coronary microvessels. Am. J. Physiol. (Heart Circ. Physiol.)285:H2309-H2315, 2003.#

43. Spector, A.A., Fang, X., Snyder, G.D., and Weintraub, N.L.: Epoxyeicosatrienoic acids (EETs): Metabolism and biochemical function. Prog. Lipid Res. 43:55-90, 2004.#

44. Chang, L., Ren, Y., Liu, X., Li, W.G., Yang, J., Geng, B., Weintraub, N.L., and Tang, C.: Protective effects of Ghrelin on ischemia-reperfusion injury in the isolated rat heart. J. Cardiovasc. Pharm. 43:165-170, 2004.#

45. Kaduce, T.L., Fang, X., Harmon, S.D., Oltman, C.L., Dellsperger, K.C., Teesch, L.M. Gopal, V.R., Falck, J.R., Campbell, W.B., Weintraub, N.L., and Spector, A.A.: 20-Hydroxyeicosatetraenoic acid (20-HETE) metabolism in coronary endothelial cells. J. Biol. Chem. 279:2648-2656, 2004.#

46. Nerheim, P.L., Meier, J.L., Vasef, M.A., Li, W.G., Hu, L., Rice, J.B., Gavrila D., Richenbacher, W.E., and Weintraub, N.L.: Enhanced cytomegalovirus infection in atherosclerotic human blood vessels. Am. J. Pathol. 164:589-600, 2004.+

47. Stoll, L.L., Denning, G.M., and Weintraub, N.L.: Potential role of endotoxin as a pro-inflammatory mediator of atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 24:2227-2236, 2004.+

48. Stoll, L.L., McCormick, M.L., Denning, G.M., and Weintraub, N.L.: Antioxidant effects of statins. Drugs Today 40:975-990, 2004.+

49. Li, W.G., Gavrila, D. Liu, X., Wang, L., Gunnlaugsson, S., Stoll, L.L., McCormick, M.L., Sigmund, C.D., Tang, C., and Weintraub, N.L. Ghrelin inhibits

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proinflammatory responses and nuclear factor-kB activation in human endothelial cells. Circulation 109:2221-2226, 2004.+

50. Stoll, L.L., Denning, G.M., Li, W-G., Rice, J.B., Harrelson, A.L., Romig, S.A., Jones, A.D., Gunnlaugsson, S.T., Miller, F.J. Jr., and Weintraub N.L. Regulation of endotoxin-induced pro-inflammatory activation in human coronary artery cells: Expression of functional mCD14 by human coronary artery smooth muscle cells. J. Immunology 173:1336-1343, 2004.+

51. Fang, X, Weintraub, N.L., McCaw, R.B., Hua, S., Harmon, S., Rice, J.B., Hammock, B.D., and Spector, A.A. Effect of soluble epoxide hydrolase inhibition on epoxyeicosatrienoic acid metabolism in human blood vessels. Am. J. Physiol. (Heart & Circ. Physiol) 287:H2412-H2420, 2004.#

52. Kabra R., Welke K.F., Kernstine K.H., Field F.J., Thompson B.H., Vats H.S., and Weintraub N.L. Bacterial pericarditis due to group F streptococcus as a complication of esophagomediastinal fistula. Ann. Thoracic Surg. 79:2132-2134, 2005.+

53. Fang, X., Hu, S., Watanabe, T., Weintraub, N.L., Snyder, G.D., Yao, J., Liu, Y., Shyy, J. Y-L., Hammock, B.D., and Spector, A.A.: Activation of peroxisomal proliferator-activated receptor- by substituted urea-derived soluble epoxide hydrolase inhibitors. J Pharmacol Exp Ther. 314:260-270, 2005.#

54. Gavrila, D., Li, W.-G., Daugherty, A., Cassis, L.A., Miller, F.J. Jr,, Oberley, L.W., Dellsperger, K.C., and Weintraub, N.L. Vitamin E inhibits abdominal aortic aneurysm formation in angiotensin II-infused, apolipoproteinE-deficient mice. Arterioscler. Thromb. Vasc. Biol. 25:1671-1677, 2005.+

55. Collins, X.H., Harmon, S.D., Kaduce, T.L., Berst, K.B., Fang, X., Moore, S.A., Raju, T.V., Falck, J.R., Weintraub, N.L., Duester, G., Plapp, B.V., and Spector, A.A.: Omega-oxidation of 20-hydroxyeicosatetraenoic acid (20-HETE) in microvascular smooth muscle and endothelium by alcohol dehydrogenase 4. J. Biol. Chem. 280:33157-33164, 2005.#

56. Stoll LL, McCormick ML, Denning GM, Weintraub NL. Antioxidant effects of statins. Timely Top Med Cardiovasc Dis. 2005 Feb 4;9:E1.+

57. Fang, X., Hu, S., Xu, B., Harmon, S., Yao, J., Liu, Y., Shyy, J., Sangras, B., Falck, J.R., Weintraub, N.L., and Spector, A.A. 14,15-Dihydroxyeicosatrienoic acid activates peroxisome proliferators-activated receptor. Am. J. Physiol. (Heart Circ. Physiol) 290:H55-H63, 2006.#

58. Coyle, C.H., Martinez, L.J., Coleman, M.C., Spitz, D.R., Weintraub, N.L., Kader, K.N. Mechanisms of H2O2-induced oxidative stress In endothelial cells. Free Rad. Biol. Med. 40:2206-2213, 2006.#

59. Thomas M., Gavrila, D., McCormick M.L., Miller, F.J. Jr, Daugherty, A., Cassis, L.A., , Dellsperger, K.C., and Weintraub, N.L. Deletion of p47phox Attenuates Angiotensin II-Induced Abdominal Aortic Aneurysm Formation in Apolipoprotein E-Deficient Mice. Circulation. 114:404-413, 2006.+

60. Fang X, Faraci FM, Kaduce TL, Harmon S, Modrick ML, Hu S, Moore SA, Falck JR, Weintraub NL, and Spector AA. 20-Hydroxyeicosatetraenoic acid (20-HETE) is a potent dilator of mouse basilar artery: Role of cyclooxygenase. Am. J. Physiol. (Heart Circ. Physiol). 291:H2301-H2307, 2006.#

61. Stoll LL, Denning GM, Weintraub NL. Endotoxin, TLR4 signaling and vascular inflammation: potential therapeutic targets in cardiovascular disease. Curr Pharm Des. 12:4229-4245, 2006.+

62. McCormick ML, Gavrila D, Weintraub NL. Role of oxidative stress in the pathogenesis of abdominal aortic aneurysms. Arterioscler Thromb Vasc Biol. 27:461-469, 2007.+

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63. Shaheen M and Weintraub NL. Osteopontin: a bona fide mediator of abdominal aortic aneurysm? (Editorial) Arterioscler Thromb Vasc Biol. 27:439-441, 2007.+

64. Denning GM, Ackermann LW, Barna TJ, Armstrong JG, Stoll LL, Weintraub NL, Dickson EW. Proenkephalin expression and enkephalin release are widely observed in non-neuronal tissues. Peptides. 29:83-92, 2008.#

65. Qin Z, Reszka KJ, Fukai T, Weintraub NL. Extracellular superoxide dismutase (ecSOD) in vascular biology: an update on exogenous gene transfer and endogenous regulators of ecSOD. Transl Res. 2008;151:68-78.+

66. Snyder GD, Oberley-Deegan RE, Goss KL, Romig-Martin SA, Stoll LL, Snyder JM, Weintraub NL. Surfactant Protein D Functions as an Anti-Inflammatory Mediator in Human Coronary Artery Smooth Muscle Cells. Am. J. Physiol. (Heart Circ. Physiol). 2008;294:H2053-H2059.+

67. Heart Failure Executive Committee, Peacock WF, Fonarow GC; Heart Failure Diagnosis Subcommittee, Ander DS, Maisel A, Hollander JE, Januzzi JL Jr, Yancy CW; Heart Failure Risk Stratification Subcommittee, Collins SP, Gheorghiade M, Weintraub NL, Storrow AB, Pang PS, Abraham WT, Hiestand B; Heart Failure Treatment Subcommittee, Kirk JD, Filippatos G, Gheorghiade M, Pang PS, Levy P, Amsterdam EA. Society of Chest Pain Centers Recommendations for the evaluation and management of the observation stay acute heart failure patient: a report from the Society of Chest Pain Centers Acute Heart Failure Committee. Crit Pathw Cardiol. 2008 Jun;7:83-6.^

68. Chatterjee TK, Stoll LL, Denning GM, Harrelson A, Blomkalns AL, Idelman G, Rothenberg FG, Neltner B, Romig-Martin SA, Dickson EW, Rudich S, Weintraub NL. Proinflammatory phenotype of perivascular adipocytes: influence of high-fat feeding. Circ Res. 2009 Feb 27;104:541-549.+

69. Rahman S, Abdul-Waheed M, Helmy T, Huffman LC, Koshal V, Guitron J, Merrill WH, Lewis DF, Dunlap S, Shizukuda Y, Weintraub NL, Meyer C, Cilingiroglu M. Spontaneous left main coronary artery dissection complicated by pseudoaneurysm formation in pregnancy: role of CT coronary angiography. J Cardiothorac Surg. 2009 Apr 1;4:15.#

70. Peacock WF, Fonarow GC, Ander DS, Collins SP,Gheorghiade M, Kirk JD, Filippatos G, Diercks DB, Trupp RJ, Hiestand B, Amsterdam EA, Dodge G, Gaieski DF, Gurney D, Hayes CO, Hollander JE, Holmes K, Januzzi JL Jr, Levy P, Maisel A, Miller CD, Pang PS, Selby E, Storrow AB, Weintraub NL, Yancy CW, Bahr RD, Blomkalns AL, McCord J, Nowak RM and Stomel RJ. Society of Chest Pain Centers recommendations for the evaluation and management of the observation stay acute heart failure patient-part 1. Acute Card Care. 2009;11:3-42.^

71. Singhal S, Yousuf MA, Weintraub NL, Shizukuda Y. Use of bicycle exercise echocardiography for unexplained exertional dyspnea. Clin Cardiol. 2009;32:302-6.#

72. Weintraub, NL. Understanding Abdominal Aortic Aneurysm. N Engl J Med 2009;361:1114-1116.*

73. Jones WK, Fan GC, Liao S, Zhang JM, Wang Y, Weintraub NL, Kranias EG, Schultz JE, Lorenz J and Ren X. Peripheral Nociception Associated With Surgical Incision Elicits Remote Nonischemic Cardioprotection Via Neurogenic Activation of Protein Kinase C Signaling. Circulation.2009;120(11 Suppl):S1-9.#

74. Qin Z, Konaniah ES, Neltner B, Nemenoff RA, Hui DY, Weintraub NL. Participation of ATP7A in macrophage mediated oxidation of low density lipoprotein. J Lipid Res. 2010;51:1471-1477.+

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75. Rajsheker S, Manka D, Blomkalns A, Chatterjee TK, Stoll LL, Weintraub, NL. Crosstalk between perivascular adipose tissue and blood vessels. Curr Opin Pharmacol. 2010 Apr;10:191-196.+

76. Blomkalns AL, Chatterjee T, Weintraub NL. Turning ACS Outside In - Linking Perivascular Adipose Tissue to Acute Coronary Syndromes. (Editorial) Am J Physiol (Heart Circ Physiol). 2010;298:H734-H735.+

77. Weintraub, NL, Jones WK, Manka D. Understanding radiation-induced vascular disease. (Editorial) J Am Coll Cardiol. 2010;55:1237-1239.*

78. Weintraub NL, Collins SP, Pang PS, Levy PD, Anderson AS, Arslanian-Engoren C, Gibler WB, McCord JK, Parshall MB, Francis GS, Gheorghiade M. Acute heart failure syndromes: emergency department presentation, treatment, and disposition; current approaches and future aims; a scientific statement from the American Heart Association. American Heart Association Council on Clinical Cardiology and Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitation. Circulation. 2010;122:1975-1996.^

79. Kim HW, Chan Q, Afton SE, Caruso JA, Lai B, Weintraub NL, Qin Z. Human Macrophage ATP7A is localized in the trans-Golgi Apparatus, Controls Intracellular Copper Levels, and Mediates Macrophage Responses to Dermal Wounds. Inflammation. 2011;35:167-175.#

80. Blomkalns AL, Stoll LL, Shaheen W, Romig-Martin SA, Dickson EW, Weintraub NL, Denning GM. Low level bacterial endotoxin activates two distinct signaling pathways in human peripheral blood mononuclear cells. J Inflamm (Lond). 2011 Feb 25;8:4.#

81. Chatterjee TK, Idelman G, Blanco V, Blomkalns AL, Piegore MG Jr, Weintraub DS, Kumar S, Rajsheker S, Manka D, Rudich SM, Tang Y, Hui DY, Bassel-Duby R, Olson EN, Lingrel JB, Ho SM, Weintraub NL. Histone deacetylase 9 is a negative regulator of adipogenic differentiation. J Biol Chem. 2011 Aug 5;286:27336-27347.+

82. Losordo DW, Henry TD, Davidson C, Sup Lee J, Costa MA, Bass T, Mendelsohn F, Fortuin FD, Pepine CJ, Traverse JH, Amrani D, Ewenstein BM, Riedel N, Story K, Barker K, Povsic TJ, Harrington RA, Schatz RA; ACT34-CMI Investigators. Intramyocardial, autologous CD34+ cell therapy for refractory angina. Circ Res. 2011;109:428-436.^

83. Gao L, Siu KL, Chalupsky K, Nguyen A, Chen P, Weintraub NL, Galis Z, Cai H. Role of uncoupled endothelial nitric oxide synthase in abdominal aortic aneurysm formation: treatment with folic acid. Hypertension. 2012;59:158-166.#

84. Xu S, Shriver AS, Jagadeesha DK, Chamseddine AH, Sz?cs K, Weintraub NL, Griendling KK, Bhalla RC, Miller FJ Jr. Increased Expression of Nox1 in Neointimal Smooth Muscle Cells Promotes Activation of Matrix Metalloproteinase-9. J Vasc Res. 2012;49:242-248.#

85. Collins SP, Lindsell CJ, Storrow AB, Fermann GJ, Levy PD, Pang PS, Weintraub NL, Frank Peacock W, Sawyer DB, Gheorghiade M. Early changes in clinical characteristics after emergency department therapy for acute heart failure syndromes: identifying patients who do not respond to standard therapy. Heart Fail Rev. 2012;17:387-394.#

86. Chen L, Ashraf M, Wang Y, Zhou M, Zhang J, Qin G, Rubinstein J, Weintraub NL, Tang Y. The role of Notch 1 activation in cardiosphere derived cell differentiation. Stem Cells Dev. 2012; 21:2122-2129.#

87. Cash JG, Kuhel DG, Basford JE, Jaeschke A, Chatterjee TK, Weintraub NL, Hui DY. Apolipoprotein E4 Impairs Macrophage Efferocytosis and Potentiates

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Apoptosis by Accelerating Endoplasmic Reticulum Stress. J Biol Chem. 2012;287:27876-27884.#

88. Collins SP, Hart KW, Lindsell CJ, Fermann GJ, Weintraub NL, Miller KF, Roll SN, Sperling MI, Sawyer DB, Storrow AB. Elevated urinary neutrophil gelatinase-associated lipocalcin after acute heart failure treatment is associated with worsening renal function and adverse events. Eur J Heart Fail. 2012; 14:1020-1029.#

89. Henry-Okafor Q, Collins SP, Jenkins CA, Miller KF, Maron DJ, Naftilan AJ, Weintraub N, Fermann GJ, McPherson J, Menon S, Sawyer D, Storrow AB. Soluble ST2 as a Diagnostic and Prognostic Marker for Acute Heart Failure Syndromes. Open Biomarkers J. 2012;5:1-8.#

90. Weintraub NL. The role of inflammation in health and disease: translating discovery into novel therapeutic approaches. Translational research: the journal of laboratory and clinical medicine. 2012;160:97-98. NIHMSID: NIHMS381428 PMID: 23565133 PMCID: PMC3614001

91. Henry-Okafor Q, Collins S, Jenkins C, Miller K, Maron K, Naftilan A, McPherson J, Fermann G, Weintraub N, Menon S, Sawyer D, Storrow AB. Relationship between uric acid levels and diagnostic and prognostic outcomes in acute heart failure. Open Biomarkers J. 2012;5:9-15.#

92. Tang Y, Wang Y, Chen L, Pan Y, Weintraub N. Cross talk between the Notch signaling and noncoding RNA on the fate of stem cells. Prog Mol Biol Transl Sci. 2012;111:175-93.#

93. Kuhel DG, Konaniah ES, Basford JE, McVey C, Goodin CT, Chatterjee TK, Weintraub NL, Hui DY. Apolipoprotein E2 Accentuates Postprandial Inflammation and Diet-Induced Obesity to Promote Hyperinsulinemia in Mice. Diabetes. 2013;62:382-391.#

94. Fermann GJ, Lindsell CJ, Storrow AB, Hart K, Sperling M, Roll S, Weintraub NL, Miller KF, Maron DJ, Naftilan AJ, McPherson JA, Sawyer DB, Christenson R, Collins SP. Galectin 3 complements BNP in risk stratification in acute heart failure. Biomarkers. 2012;17:706-713.#

95. Collins SP, Lindsell CJ, Jenkins CA, Harrell FE, Fermann GJ, Miller KF, Roll SN, Sperling MI, Maron DJ, Naftilan AJ, McPherson JA, Weintraub NL, Sawyer DB, Storrow AB. Risk stratification in acute heart failure: Rationale and design of the STRATIFY and DECIDE studies. Am Heart J. 2012;164:825-834.^

96. Carpenter WE, Lam D, Toney GM, Weintraub NL, Qin Z. Zinc, copper, and blood pressure: Human population studies. Med Sci Monit. 2013;19:1-8.

97. Chen L, Wang Y, Pan Y, Zhang L, Shen C, Qin G, Ashraf M, Weintraub N, Ma G, Tang Y. Cardiac progenitor-derived exosomes protect ischemic myocardium from acute ischemia/reperfusion injury. Biochem Biophys Res Commun. 2013;431:566-571.#

98. Blomkalns AL, Gavrila D, Thomas M, Neltner BS, Blanco VM, Benjamin SB, McCormick ML, Stoll LL, Denning GM, Collins SP, Qin Z, Daugherty A, Cassis LA, Thompson RW, Weiss RM, Lindower PD, Pinney SM, Chatterjee T, Weintraub NL. CD14 directs adventitial macrophage precursor recruitment: role in early abdominal aortic aneurysm formation. J Am Heart Assoc. 2013;2:e000065.+

99. Park S, Lu KT, Liu X, Chatterjee TK, Rudich SM, Weintraub NL, Kwitek AE, Sigmund CD. Allele-specific expression of angiotensinogen in human subcutaneous adipose tissue. Hypertension. 2013;62:41-47.#

100. Wang Y, Zhang L, Pan Y, Chen L, Weintraub N, Tang Y. Identification of stem cells after transplantation. Methods Mol Biol. 2013;1036:89-94.# Tang YL,

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Wang YJ, Chen LJ, Pan YH, Zhang L, Weintraub NL. Cardiac-derived stem cell-based therapy for heart failure: progress and clinical applications. Exp Biol Med (Maywood). 2013;238:294-300.+

101. Weintraub NL, Rubinstein J. Cooling the Fire of Atherosclerosis with Heat Shock Protein 27. J Am Coll Cardiol. 2013; 62(16):1455-1456.+

102. Lynch M, O'Donnell R, Weintraub NL, López-Candales A. Assessment of Mitral Annular and Velocity Vector Imaging in Acute Myopericarditis. Echocardiography. 2013; 30(8):E227-E230.#

103. Chatterjee TK, Aronow BJ, Tong WS, Manka D, Tang Y, Bogdanov VY, Unruh D, Blomkalns AL, Piegore MG Jr, Weintraub DS, Rudich SM, Kuhel DG, Hui DY, Weintraub NL. Human coronary artery perivascular adipocytes over-express genes responsible for regulating vascular morphology, inflammation, and hemostasis. Physiol Genomics. 2013; 45:697-709.+

104. Basford JE, Koch S, Anjak A, Singh VP, Krause EG, Robbins N, Weintraub NL, Hui DY, Rubinstein J. Smooth muscle LDL receptor-related protein-1 deletion induces aortic insufficiency and promotes vascular cardiomyopathy in mice. PLoS One. 2013;8:e82026.#

105. Chatterjee TK, Basford JE, Knoll E, Tong WS, Blanco V, Blomkalns AL, Rudich S, Lentsch AB, Hui DY, Weintraub NL. HDAC9 Knockout Mice Are Protected From Adipose Tissue Dysfunction and Systemic Metabolic Disease During High-Fat Feeding. Diabetes. 2014;63:176-187.+

106. Zhang L, Pan Y, Qin G, Chen L, Chatterjee TK, Weintraub NL, Tang Y. Inhibition of stearoyl-coA desaturase selectively eliminates tumorigenic Nanog-positive cells: Improving the safety of iPS cell transplantation to myocardium. Cell Cycle. 2014;13:762-771.#

107. Zhang L, Zhou M, Qin G, Weintraub NL, Tang Y. MiR-92a regulates viability and angiogenesis of endothelial cells under oxidative stress. Biochem Biophys Res Commun. 2014; 446:952-958.#

108. Zhang L, Zhou M, Wang Y, Huang W, Qin G, Weintraub NL, Tang Y. miR-92a inhibits vascular smooth muscle cell apoptosis: role of the MKK4-JNK pathway. Apoptosis. 2014;16:975-983.#

109. Ranganathan P, Jayakumar C, Mohamed R, Weintraub NL, Ramesh G. Semaphorin 3A inactivation suppresses ischemia/reperfusion-induced inflammation and acute kidney injury. Am J Physiol Renal Physiol. 307:F183-F194, 2014.#

110. Waltmann MD, Basford JE, Konaniah ES, Weintraub NL, Hui DY. Apolipoprotein E receptor-2 deficiency enhances macrophage susceptibility to lipid accumulation and cell death to augment atherosclerotic plaque progression and necrosis. Biochim Biophys Acta. 1842:1395-1405, 2014.#

111. Wang Y, Wang X, Qin G, Weintraub NL, Tang Y. Assessing in vitro stem cell function and tracking engraftment of stem cells in ischemic hearts using novel iRFP gene labeling. J Cell Mol Med. 2014; 18:1889-1894.#

112. Chatterjee TK, Yiew KH, Stepp DW, Hui DY, Weintraub NL. Role of histone deacetylase 9 in regulating adipogenic differentiation and high fat diet-induced metabolic disease. Adipocyte. 2014; 3:333-338.#

113. Omar A, Chatterjee TK, Tang Y, Hui DY, Weintraub NL. Proinflammatory phenotype of perivascular adipocytes. Arterioscl Thromb Vasc Biol. 34: 1631-1636, 2014.+

114. Manka D, Chatterjee TK*, Stoll LL, Basford JE, Konaniah ES, Srinivasan R, Bogdanov VY, Tang Y, Blomkalns AL, Hui DY, Weintraub NL. Transplanted

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perivascular adipose tissue accelerates injury-induced neointimal hyperplasia: role of MCP-1. Arterioscl Thromb Vasc Biol. 34:1723-1730, 2014.+

115. Mohamed R, Ranganathan P, Jayakumar C, Nauta FL, Gansevoort RT, Weintraub NL, Brands M, Ramesh G. Urinary semaphorin 3A correlates with diabetic proteinuria and mediates diabetic nephropathy and associated inflammation in mice. J Mol Med (Berl). 2014;92:1245-1256.#

116. Pan A, Weintraub NL, Tang Y. Enhancing stem cell survival in an ischemic heart by CRISPR-dCas9-based gene regulation. Med Hypotheses. 2014;83:702-705.#

117. Chen L, Phillips MI, Miao HL, Zeng R, Qin G, Kim IM, Weintraub NL, Tang Y. Infrared fluorescent protein 1.4 genetic labeling tracks engrafted cardiac progenitor cells in mouse ischemic hearts. PLoS One. 2014;9:e107841.#

118. Xu J, Donepudi AC, More VR, Kulkarni SR, Li L, Guo L, Yan B, Chatterjee T, Weintraub N, Slitt AL. Deficiency in Nrf2 transcription factor decreases adipose tissue mass and hepatic lipid accumulation in leptin-deficient mice. Obesity (Silver Spring). 2015;23:335-344.#

119. Tung W, Weintraub NL, Berman AE, Tang Y. A novel high throughput approach to screen for cardiac arrhythmic events following stem cell treatment. Med Hypotheses. 2015;84:294-297.#

120. Baban B, Liu JY, Qin X, Weintraub NL, Mozaffari MS. Upregulation of Programmed Death-1 and Its Ligand in Cardiac Injury Models: Interaction with GADD153. PLoS One. 2015;10:e0124059.#

121. Wang Y, Zhang L, Li Y, Chen L, Wang X, Guo W, Zhang X, Qin G, He SH, Zimmerman A, Liu Y, Kim IM, Weintraub NL, Tang Y. Exosomes/microvesicles from induced pluripotent stem cells deliver cardioprotective miRNAs and prevent cardiomyocyte apoptosis in the ischemic myocardium. Int J Cardiol. 2015;192:61-69.#

122. Teoh JP, Park KM, Broskova Z, Jimenez FR, Bayoumi A, Archer K, Su H, Johnson J, Weintraub NL, Tang Y, Kim IM. Identification of gene signatures regulated by carvedilol in mouse heart. Physiol Genomics. 2015; 47:376-385.

123. Yiew KH, Chatterjee TK, Hui DY, Weintraub NL. Histone Deacetylases and Cardiometabolic Diseases. Arterioscler Thromb Vasc Biol. 2015; 35:1914-1919.+

124. Zhou H, Lei X, Benson T, Mintz J, Xu X, Harris RB, Weintraub NL, Wang X, Chen W. Berardinelli-Seip congenital lipodystrophy 2 regulates adipocyte lipolysis, browning, and energy balance in adult animals. J Lipid Res. 2015;56:1912-1925.#

125. Collins SP, Jenkins CA, Harrell FE Jr, Liu D, Miller KF, Lindsell CJ, Naftilan AJ, McPherson JA, Maron DJ, Sawyer DB, Weintraub NL, Fermann GJ, Roll SK, Sperling M, Storrow AB. Identification of Emergency Department Patients With Acute Heart Failure at Low Risk for 30-Day Adverse Events: The STRATIFY Decision Tool. JACC Heart Fail. 2015;3:737-747.^

126. Chen F, Haigh S, Yu Y, Benson T, Wang Y, Li X, Dou H, Bagi Z, Verin AD, Stepp DW, Csanyi G, Chadli A, Weintraub NL, Smith SM, Fulton DJ. Nox5 stability and superoxide production Is regulated by C-terminal binding of Hsp90 and CO-chaperones. Free Radic Biol Med. 2015;89:793-805.#

127. Unruh D, Srinivasan R, Benson T, Haigh S, Coyle D, Batra N, Keil R, Sturm R, Blanco V, Palascak M, Franco RS, Tong W, Chatterjee T, Hui DY, Davidson WS, Aronow BJ, Kalfa T, Manka D, Peairs A, Blomkalns A, Fulton DJ, Brittain JE, Weintraub NL, Bogdanov VY. Red blood cell dysfunction induced by high-fat diet: potential implications for obesity-related atherosclerosis.

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Circulation. 2015;132:1898-1908.+ (Drs. Weintraub and Bogdanov contributed equally).

128. Romero MJ. Lucas R, Doua H, Sridhara S, Czikoraa I, Mosieria E, Ricke FG, Sridhard S, Fulton D, Weintraub NL, Bagi Z, Schally AV. Role of Growth Hormone-Releasing Hormone in dyslipidemia associated with experimental type 1 diabetes. Proc Natl Acad Sci USA. 2016;113:1895-900.#

129. Campbell CR, Berman AE, Weintraub NL, Tang YL. Electrical stimulation to optimize cardioprotective exosomes from cardiac stem cells. Med Hypotheses. 2016;88:6-9.#

130. Zhou H, Black SM, Benson TW, Weintraub NL, Chen W. Berardinelli-Seip Congenital Lipodystrophy 2 (BSCL2)/SEIPIN is not required for Brown Adipogenesis but Regulates Brown Adipose Tissue Development and Function. Mol Cell Biol. 2016; 36(15):2027-38.#

131. Park KM, Teoh JP, Wang Y, Broskova Z, Bayoumi A, Tang Y, Su H, Weintraub NL, Kim IM. Carvedilol-responsive microRNAs, miR-199a-3p and -214 protect cardiomyocytes from simulated ischemia-reperfusion injury. Am J Physiol Heart Circ Physiol. 2016; 311(2):H371-H383.#

132. Chen F, Li X, Aquadro E, Haigh S, Zhou J, Stepp DW, Weintraub NL, Barman SA, Fulton DJ. Inhibition of Histone Deacetylase Reduces Transcription of NADPH Oxidases and ROS production and Ameliorates Pulmonary Arterial Hypertension. Free Radic Biol Med; 2016;99:167-178.#

133. Cuomo JR, Sharma GK, Conger PD, Weintraub NL. Novel Concepts in Radiation-Induced Cardiovascular Disease. World J Cardiol; 2016;8:504-519.+

134. Kim HW, Weintraub NL. Aortic Aneurysm: In Defense of the Vascular Smooth Muscle Cell. Arterioscler Thromb Vasc Biol. 2016;36:2138-2140.+

135. Li J, Ma W, Yue G, Tang Y, Kim IM, Weintraub NL, Wang X, Su H. Cardiac proteasome functional insufficiency plays a pathogenic role in diabetic cardiomyopathy. J Mol Cell Cardiol. 2017;102:53-60. #

136. Yiew NKH, Chatterjee TK, Tang YL, Pellenberg R, Stansfield BK, Bagi Z, Fulton DJ, Stepp DW, Chen W, Patel V, Kamath VM, Litwin SE, Hui DY, Rudich SM, Kim HW, Weintraub NL. A novel role for the Wnt inhibitor APCDD1 in adipocyte differentiation: Implications for diet-induced obesity. J Biol Chem. 2017;292:6312-6324.+

137. Konaniah ES, Kuhel DG, Basford JE, Weintraub NL, Hui DY. Deficiency of LRP1 in Mature Adipocytes Promotes Diet-Induced Inflammation and Atherosclerosis-Brief Report. Arterioscler Thromb Vasc Biol. 2017;37:1046-1049.#

138. Dou H, Feher A, Davila AC, Romero MJ, Patel VS, Kamath VM, Gooz MB, Rudic RD, Lucas R, Fulton DJ, Weintraub NL, Bagi Z. Role of Adipose Tissue Endothelial ADAM17 in Age-Related Coronary Microvascular Dysfunction. Arterioscler Thromb Vasc Biol. 2017;37:1180-1193.#

139. Xu Y, Wang Y, Yan S, Zhou Y, Yang Q, Pan Y, Zeng X, An X, Liu Z, Wang L, Xu J, Cao Y, Fulton DJ, Weintraub NL, Bagi Z, Hoda MN, Wang X, Li Q, Hong M, Jiang X, Boison D, Weber C, Wu C, Huo Y. Intracellular adenosine regulates epigenetic programming in endothelial cells to promote angiogenesis. EMBO Mol Med. 2017; 9:1263-1278.#

140. Bayoumi AS, Teoh J-P, Aonuma T, Yuan Z, Ruan X, Tang Y, Su H, Weintraub NL, Kim I-m. MicroRNA-532 protects the heart in acute myocardial infarction by repressing a positive regulator of endothelial-to-mesenchymal transition, prss23. Cardiovasc Res. 2017;113:1603-1614.#

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141. Chen Z, Li Y, Yu H, Shen Y, Ju C, Ma G, Liu Y, Kim IM, Weintraub NL, Tang Y. Isolation of Extracellular Vesicles from Stem Cells. Methods Mol Biol. 2017;1660:389-394#.

142. Liu Z, Yan S, Wang J, Xu Y, Wang Y, Zhang S, Xu X, Yang Q, Zeng X, Zhou Y, Gu X, Lu S, Fu Z, Fulton D, Weintraub N, Caldwell R, Zhang W, Wu C, Liu X-L, Chen J-F, Ahmad A, Kaddour-Djebbar I, Al-Shabrawey M, Li Q, Jiang X, Sun Y, Sodhi A, Smith L, Hong M, Huo Y. Endothelial adenosine A2a receptor-mediated glycolysis is essential for pathological retinal angiogenesis. Nat Commun. 2017; 8:584.#

143. Xu Y, Wang Y, Yan S, Yang Q, Zhou Y, Zeng X, Liu Z, An X, Toque H, Dong Z, Jiang X, Fulton D, Weintraub N, Li Q, Bagi Z, Hong M, Boison D, Wu C, Huo Y. Regulation of Endothelial Intracellular Adenosine via Adenosine Kinase Epigenetically Modulates Vascular Inflammation. Nat Commun. 2017; 8:943.#

144. Kim HW, Blomkalns AL, Ogbi M, Thomas M, Gavrila D, Neltner BS, Cassis LA, Thompson RW, Weiss RM, Lindower PD, Blanco VM, McCormick ML, Daugherty A, Fu X, Hazen SL, Stansfield BK, Huo Y, Fulton DJ, Chatterjee T, Weintraub NL. Role of myeloperoxidase in abdominal aortic aneurysm formation: mitigation by taurine. Am J Physiol Heart Circ Physiol. 2017;313:H1168-H1179.+

145. Bayoumi AS, Park KM, Wang Y, Teoh JP, Aonuma T, Tang Y, Su H, Weintraub NL, Kim IM. A carvedilol-responsive microRNA, miR-125b-5p protects the heart from acute myocardial infarction by repressing pro-apoptotic bak1 and klf13 in cardiomyocytes. J Mol Cell Cardiol. 2017;114:72-82.#

146. Horimatsu T, Kim HW, Weintraub NL. The Role of Perivascular Adipose Tissue in Non-atherosclerotic Vascular Disease. Front Physiol. 2017;8:969.+

147. Hagan M, Ashraf M, Kim IM, Weintraub NL, Tang Y. Effective regeneration of dystrophic muscle using autologous iPSC-derived progenitors with CRISPR-Cas9 mediated precise correction. Med Hypotheses. 2018;110:97-100. doi: 10.1016/j.mehy.2017.11.009. Epub 2017 Nov 23. PMID: 29317080#

148. Whiteside HL, Jyothisdasa A, Obeidin F, Vyas S, Weintraub N, Sharma GK; Evaluation of Routine Screening Practices for Cardiac Involvement in Patients with Biopsy-Proven Extracardiac Sarcoidosis. Heart Circ 2017; 1:008.#

149. Benson TW, Weintraub DS, Crowe M, Yiew NKH, Popoola O, Pillai A, Joseph J, Archer K, Greenway C, Chatterjee TK, Mintz J, Stepp DW, Stansfield BK, Chen W, Brittain J, Bogdanov VY, Gao Y, Wilson JG, Tang Y, Kim HW, Weintraub NL. Deletion of the Duffy antigen receptor for chemokines (DARC) promotes insulin resistance and adipose tissue inflammation during high fat feeding. Mol Cell Endocrinol. 2018; 15;473:79-88.+

150. Hagan M, Zhou M, Ashraf M, Kim IM, Su H, Weintraub NL, Tang Y. Long noncoding RNAs and their roles in skeletal muscle fate determination. Noncoding RNA Investig. 2017 Dec;1. pii: 24. doi: 10.21037/ncri.2017.12.01. Epub 2017 Dec 13. PMID: 29451560.#

151. Lino Cardenas CL, Kessinger CW, Cheng Y, MacDonald C, MacGillivray T, Ghoshhajra B, Huleihel L, Nuri S, Yeri AS, Jaffer FA, Kaminski N, Ellinor P, Weintraub NL, Malhotra R, Isselbacher EM, Lindsay ME. An HDAC9-MALAT1-BRG1 complex mediates smooth muscle dysfunction in thoracic aortic aneurysm. Nat Commun. 2018 Mar 8;9(1):1009.#

152. Ruan XF, Ju CW, Shen Y, Liu YT, Kim IM, Yu H, Weintraub N, Wang XL, Tang YL. Suxiao Jiuxin pill promotes exosome secretion from mouse cardiac mesenchymal stem cells in vitro. Acta Pharmacol Sin. 2018;39:569-578.#

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153. Ruan XF, Li YJ, Ju CW, Shen Y, Lei W, Chen C, Li Y, Yu H, Liu YT, Kim IM, Wang XL, Weintraub NL, Tang YL. Exosomes from Suxiao Jiuxin Pill-treated cardiac mesenchymal stem cells decrease H3K27 demethylase UTX expression in mouse cardiomyocytes in vitro. Acta Pharmacol Sin. 2018; 39:579-586. #

154. Benson TW, Weintraub NL, Kim HW, Seigler N, Kumar S, Pye J, Horimatsu T, Pellenberg R, Stepp DW, Lucas R, Bogdanov VY, Litwin SE, Brittain JE, Harris RA. A single high-fat meal provokes pathological erythrocyte remodeling and increases myeloperoxidase levels: implications for acute coronary syndrome. Lab Invest. 2018;98:1300-1310.+

155. Teoh JP, Bayoumi AS, Aonuma T, Xu Y, Johnson JA, Su H, Weintraub NL, Tang Y, Kim IM. β-arrestin-biased agonism of β-adrenergic receptor regulates Dicer-mediated microRNA maturation to promote cardioprotective signaling. J Mol Cell Cardiol. 2018;118:225-236.#

156. Zou J, Ma W, Li J, Littlejohn R, Zhou H, Kim IM, Fulton DJR, Chen W, Weintraub NL, Zhou J, Su H. Neddylation mediates ventricular chamber maturation through repression of Hippo signaling. Proc Natl Acad Sci U S A. 2018;115:E4101-E4110.#

157. Cuomo JR, Javaheri SP, Sharma GK, Kapoor D, Berman AE, Weintraub NL. How to prevent and manage radiation-induced coronary artery disease. Heart; 104:1647-1653, 2018.+

158. Zarzour A, Kim HW, Weintraub NL. Understanding obesity-related cardiovascular disease: it’s all about balance. Circulation. 2018;138:64-66.+

159. Wang Z, Su X, Ashraf M, Kim IM, Weintraub NL, Jiang M, Tang Y. Regenerative Therapy for Cardiomyopathies. J Cardiovasc Transl Res. 2018; 11:357-365.#

160. Zhang H, Hudson FZ, Xu Z, Tritz R, Rojas M, Patel C, Haigh SB, Bordán Z, Ingram DA, Fulton DJ, Weintraub NL, Caldwell RB, Stansfield BK. Neurofibromin Deficiency Induces Endothelial Cell Proliferation and Retinal Neovascularization. Invest Ophthalmol Vis Sci. 2018;59:2520-2528.#

161. Masoumy EP, Sawyer AA, Sharma S, Patel JA, Gordon PMK, Regnault TRH, Matushewski B, Weintraub NL, Richardson B, Thompson JA, Stansfield BK. The lifelong impact of fetal growth restriction on cardiac development. Pediatr Res. 2018;84:537-544.#

162. Horimatsu T, Patel AS, Prasad R, Reid LE, Benson TW, Zarzour A, Ogbi M, Bruder do Nascimento T, Belin de Chantemele E, Stansfield BK, Lu XY, Kim HW, Weintraub NL. Remote Effects of Transplanted Perivascular Adipose Tissue on Endothelial Function and Atherosclerosis. Cardiovasc Drugs Ther. 2018;32:503-510.+

163. Su X, Jin Y, Shen Y, Ju C, Cai J, Liu Y, Kim IM, Wang Y, Yu H, Weintraub NL, Jiang M, Tang Y. Exosome-Derived Dystrophin from Allograft Myogenic Progenitors Improves Cardiac Function in Duchenne Muscular Dystrophic Mice. J Cardiovasc Transl Res. 2018;11:412-419.#

164. Ju C, Shen Y, Ma G, Liu Y, Cai J, Kim IM, Weintraub NL, Liu N, Tang Y. Transplantation of Cardiac Mesenchymal Stem Cell-Derived Exosomes Promotes Repair in Ischemic Myocardium. J Cardiovasc Transl Res. 2018; 11:420-428.#

165. Yang Q, Xu J, Ma Q, Liu Z, Sudhahar V, Cao Y, Wang L, Zeng X, Zhou Y, Zhang M, Xu Y, Wang Y, Weintraub NL, Zhang C, Fukai T, Wu C, Huang L, Han Z, Wang T, Fulton DJ, Hong M, Huo Y. PRKAA1/AMPKα1-driven glycolysis in endothelial cells exposed to disturbed flow protects against atherosclerosis. Nat Commun. 2018;9:4667.#

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166. Zhang M, Zeng X, Yang Q, Xu J, Liu Z, Zhou Y, Cao Y, Zhang X, An X, Xu Y, Huang L, Han Z, Wang T, Wu C, Fulton DJ, Weintraub NL, Hong M, Huo Y. Ablation of Myeloid ADK (Adenosine Kinase) Epigenetically Suppresses Atherosclerosis in ApoE-/- (Apolipoprotein E Deficient) Mice. Arterioscler Thromb Vasc Biol. 2018;38:2780-2792.#

167. Ren X, Roessler AE, Lynch TL 4th, Haar L, Mallick F, Liu Y, Tranter M, Ren M, Rui Xie W, Fan GC, Zhang JM, Kranias E, Anjak A, Koch SE, Jiang M, Dass S, Cohen A, Rubinstein J, Weintraub NL, Jones WK. Cardioprotection via the skin; Nociceptor-Induced Conditioning Against Cardiac MI, in the NIC of time. Am J Physiol Heart Circ Physiol. 2018 ;316(3):H543-H553. #

168. Lino Cardenas CL, Kessinger CW, Chou EL, Ghoshhajra B, Yeri AS, Das S, Weintraub NL, Malhotra R, Jaffer FA, Lindsay ME. HDAC9 complex inhibition improves smooth muscle-dependent stenotic vascular disease. JCI Insight. 2019 Jan 24;4(2). pii: 124706. doi: 10.1172/jci.insight.124706. [Epub ahead of print].#

169. Campia U, Moslehi JJ, Amiri-Kordestani L, Barac A, Beckman JA, Chism DD, Cohen P, Groarke JD, Herrmann J, Reilly CM, Weintraub NL; American Heart Association Council on Peripheral Vascular Disease; Council on Arteriosclerosis, Thrombosis and Vascular Biology; and Council on Cardiovascular and Stroke Nursing. Cardio-Oncology: Vascular and Metabolic Perspectives: A Scientific Statement From the American Heart Association. Circulation. 2019; 139(13):e579-e602.^

170. Atawia RT, Toque HA, Meghil MM, Benson TW, Yiew NKH, Cutler CW, Weintraub NL, Caldwell RB, Caldwell RW. Role of Arginase 2 in Systemic Metabolic Activity and Adipose Tissue Fatty Acid Metabolism in Diet-Induced Obese Mice. Int J Mol Sci. 2019 Mar 22;20(6).#

171. Zou J, Ma W, Littlejohn R, Li J, Stansfield BK, Kim IM, Liu J, Zhou J, Weintraub NL, Su H. Transient inhibition of neddylation at neonatal stage evokes reversible cardiomyopathy and predisposes the heart to isoproterenol-induced heart failure. Am J Physiol Heart Circ Physiol. 2019; 316(6):H1406-H1416. #

172. Sawyer AA, Pollock NK, Gutin B, Weintraub NL, Stansfield BK. Proportionality at birth and left ventricular hypertrophy in healthy adolescents. Early Hum Dev. 2019; 132:24-29.#

173. Yiew NKH, Greenway C, Zarzour A, Ahmadieh S, Goo B, Kim D, Benson TW, Ogbi M, Tang YL, Chen W, Stepp D, Patel V, Hilton R, Lu XY, Hui DY, Kim HW, Weintraub NL. Enhancer of Zeste Homolog 2 (EZH2) regulates adipocyte lipid metabolism independent of adipogenic differentiation: role of apolipoprotein E. J Biol Chem. 2019; 294(21):8577-8591. PMID: 30971429+

174. Su X, Shen Y, Weintraub NL, Tang Y. Imaging and Tracking Stem Cell Engraftment in Ischemic Hearts by Near-Infrared Fluorescent Protein (iRFP) Labeling. Methods Mol Biol. 2019 Apr 26. doi: 10.1007/7651_2019_226. [Epub ahead of print]#

175. Su X, Shen Y, Jin Y, Jiang M, Weintraub N, Tang Y. Purification and Transplantation of Myogenic Progenitor Cell Derived Exosomes to Improve Cardiac Function in Duchenne Muscular Dystrophic Mice. J Vis Exp. 2019 Apr 10;(146).#

176. Zarzour A, Kim HW, Weintraub NL. Epigenetic Regulation of Vascular Diseases. Arterioscler Thromb Vasc Biol. 2019; 39(6):984-990.+

177. Chen Z, Su X, Shen Y, Jin Y, Luo T, Kim IM, Weintraub NL, Tang Y. MiR322 mediates cardioprotection against ischemia/reperfusion injury via FBXW7/notch pathway. J Mol Cell Cardiol. 2019;133:67-74.#

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178. Zhou H, Lei X, Yan Y, Lydic T, Li J, Weintraub NL, Su H, Chen W. Targeting ATGL to rescue BSCL2 lipodystrophy and its associated cardiomyopathy. JCI Insight. 2019 Jun 11;5. pii: 129781.#

179. Cao Y, Zhang X, Wang L, Yang Q, Ma Q, Xu J, Wang J, Kovacs L, Ayon RJ, Liu Z, Zhang M, Zhou Y, Zeng X, Xu Y, Wang Y, Fulton DJ, Weintraub NL, Lucas R, Dong Z, Yuan JX, Sullivan JC, Meadows L, Barman SA, Wu C, Quan J, Hong M, Su Y, Huo Y. PFKFB3-mediated endothelial glycolysis promotes pulmonary hypertension. Proc Natl Acad Sci U S A. 2019;116(27):13394-13403.#

180. Kim HW, Belin de Chantemèle EJ, Weintraub NL. Perivascular Adipocytes in Vascular Disease. Arterioscler Thromb Vasc Biol. Nov;39(11):2220-2227.+

181. Davila A, Tian Y, Czikora I, Li J, Su H, Huo Y, Patel V, Robinson V, Kapuku G, Weintraub N, Bagi Z. Adenosine Kinase Inhibition Augments Conducted Vasodilation and Prevents Left Ventricle Diastolic Dysfunction in Heart Failure With Preserved Ejection Fraction. Circ Heart Fail. 2019 Aug;12(8):e005762.#

182. Sudhahar V, Das A, Horimatsu T, Ash D, Leanhart S, Antipova O, Vogt S, Singla B, Csanyi G, White J, Kaplan JH, Fulton D, Weintraub NL, Won Kim H, Ushio-Fukai M, Fukai T. Copper Transporter ATP7A (Copper-Transporting P-Type ATPase/Menkes ATPase) Limits Vascular Inflammation and Aortic Aneurysm Development: Role of MicroRNA-125b. Arterioscler Thromb Vasc Biol. 2019 Nov;39(11):2320-2337.#

183. Jin Y, Shen Y, Su X, Weintraub N, Tang Y. CRISPR/Cas9 Technology in Restoring Dystrophin Expression in iPSC-Derived Muscle Progenitors. J Vis Exp. 2019 Sep 14;(151).#

184. Su X, Jin Y, Shen Y, Kim IM, Weintraub NL, Tang Y. RNAase III-Type Enzyme Dicer Regulates Mitochondrial Fatty Acid Oxidative Metabolism in Cardiac Mesenchymal Stem Cells. Int J Mol Sci. 2019 Nov 7;20(22).#

185. Horimatsu T, Blomkalns AL, Ogbi M, Moses M, Kim D, Patel S, Gilreath N, Reid L, Benson TW, Pye J, Ahmadieh S, Thompson A, Robbins N, Mann A, Edgell A, Benjamin S, Stansfield BK, Huo Y, Fulton DJ, Agarwal G, Singh N, Offermanns S, Weintraub NL, Kim HW. Niacin protects against abdominal aortic aneurysm formation via GPR109A independent mechanisms: role of NAD+/nicotinamide. Cardiovasc Res. 2019 Nov 9. pii: cvz303. doi: [Epub ahead of print]. Corresponding author;+

186. Saxena R, Weintraub NL, Tang Y. Optimizing cardiac ischemic preconditioning and postconditioning via epitranscriptional regulation. Med Hypotheses. 2020 Feb;135:109451.#

187. Xuan W, Wang L, Xu M, Weintraub NL, Ashraf M. miRNAs in Extracellular Vesicles from iPS-Derived Cardiac Progenitor Cells Effectively Reduce Fibrosis and Promote Angiogenesis in Infarcted Heart. Stem Cells Int. 2019 Nov 11;2019:3726392.#

188. Ahmadieh S, Kim HW, Weintraub NL. Potential role of perivascular adipose tissue in modulating atherosclerosis. Clin Sci (Lond). 2020 Jan 17;134(1):3-13.+

189. Wang Y, Xu Y, Yan S, Cao K, Zeng X, Zhou Y, Liu Z, Yang Q, Pan Y, Wang X, Boison D, Su Y, Jiang X, Patel VS, Fulton D, Weintraub NL, Huo Y. Adenosine kinase is critical for neointima formation after vascular injury by inducing aberrant DNA hypermethylation. Cardiovasc Res. 2020 Feb 17. pii: cvaa040. doi: 10.1093/cvr/cvaa040. [Epub ahead of print]#

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190. Jin Y, Shen Y, Weintraub NL, Tang Y. Using iRFP Genetic Labeling Technology to Track Tumorogenesis of Transplanted CRISPR/Cas9-Edited iPSC in Skeletal Muscle. Methods Mol Biol. 2020;2126:73-83.#

191. Zhang Q, Schwade M, Schafer P, Weintraub N, Young L. Characterization of Sedentary Behavior in Heart Failure Patients With Arthritis. Cardiol Res. 2020 Apr;11(2):97-105.#

192. Jin Y, Shen Y, Su X, Weintraub NL, Tang Y. Effective restoration of dystrophin expression in iPSC Mdx-derived muscle progenitor cells using the CRISPR/Cas9 system and homology-directed repair technology. Comput Struct Biotechnol J. 2020 Mar 25;18:765-773.#

193. Rigger W, Javaheri SP, Sharma GK, Nahman NS Jr, Sheynshteyn M, Weintraub NL. Masked Hypotension due to Elevated Venous Pressure in a Patient with Complex Adult Congenital Heart Disease. Case Rep Cardiol. 2020 Mar 31;2020:7148708.+

194. Jin Y, Shen Y, Su X, Cai J, Liu Y, Weintraub NL, Tang Y. The Small GTPases Rab27b Regulates Mitochondrial Fatty Acid Oxidative Metabolism of Cardiac Mesenchymal Stem Cells. Front Cell Dev Biol. 2020 Apr 15;8:209.#

195. Su X, Shen Y, Jin Y, Weintraub NL, Tang YL. Identification of critical molecular pathways involved in exosome-mediated improvement of cardiac function in a mouse model of muscular dystrophy. Acta Pharmacol Sin. 2020 Jun 29. doi: 10.1038/s41401-020-0446-y. Online ahead of print.#

196. Guha A, Desai NR, Weintraub NL. Assessing cardiovascular risk in cancer patients: opportunities and challenges. Eur J Prev Cardiol. 2020 Jul 27:2047487320943002. doi: 10.1177/2047487320943002. Online ahead of print+

197. Liu Z, Xu J, Ma Q, Zhang X, Yang Q, Wang L, Cao Y, Xu Z, Tawfik A, Sun Y, Weintraub NL, Fulton DJ, Hong M, Dong Z, Smith LEH, Caldwell RB, Sodhi A, Huo Y. Glycolysis links reciprocal activation of myeloid cells and endothelial cells in the retinal angiogenic niche. Sci Transl Med. 2020 Aug 5;12(555):eaay1371.#

198. Tritz R, Benson T, Harris V, Hudson FZ, Mintz J, Zhang H, Kennard S, Chen W, Stepp DW, Csanyi G, de ChantemÈle EJB, Weintraub NL, Stansfield BK. Nf1 heterozygous mice recapitulate the anthropometric and metabolic features of human neurofibromatosis type 1. Transl Res. 2020 Aug 8:S1931-5244(20)30197-3. Online ahead of print.#

199. Won Kim H, Shi H, Winkler MA, Lee R, Weintraub NL. Perivascular Adipose Tissue and Vascular Perturbation/Atherosclerosis. Arterioscler Thromb Vasc Biol. 2020 Sep 3. Online ahead of print.+

200. Young L, Zhang Q, Lian E, Roberts K, Weintraub N, Dong Y, Zhu H, Xu H, Schafer P, Dunlap S. Factors Predicting the Utilization of Center-Based Cardiac Rehabilitation Program. Geriatrics (Basel). 2020 Sep 28;5(4):E66.#

201. Packer M, Anker SD, Butler J, Filippatos G, Pocock SJ, Carson P, Januzzi J, Verma S, Tsutsui H, Brueckmann M, Jamal W, Kimura K, Schnee J, Zeller C, Cotton D, Bocchi E, Böhm M, Choi DJ, Chopra V, Chuquiure E, Giannetti N, Janssens S, Zhang J, Gonzalez Juanatey JR, Kaul S, Brunner-La Rocca HP, Merkely B, Nicholls SJ, Perrone S, Pina I, Ponikowski P, Sattar N, Senni M, Seronde MF, Spinar J, Squire I, Taddei S, Wanner C, Zannad F; EMPEROR-Reduced Trial Investigators. Cardiovascular and Renal Outcomes with Empagliflozin in Heart Failure. N Engl J Med. 2020 Oct 8;383(15):1413-1424.^

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BOOKS AND CHAPTERS 1. Weintraub, N.L., Stephenson, A.H., Sprague, R.S., and Lonigro, A.J.: Role of

phospholipase A2 in EDHF-mediated relaxation of the porcine coronary artery. In: Endothelium-Dependent Hyperpolarizations, P.M. Vanhoutte (Ed.), Canada, Harwood Academic Publishing, pp. 97-108, 1999.*

2. Chu, Y., Weintraub, N., and Heistad, D.D.: Gene therapy and cardiovascular disease. In: Principles of Molecular Cardiology. M.S. Runge, and C. Patterson, (Eds). Totowa, NJ, Humana Press, pp. 57-69, 2005.#

3. Sanchez CE, Kapur S, Weintraub NL. Aneurysms (large and small arteries). In: Hemostasis and Thrombosis: Basic Principles and Clinical Practice (6th Edition). Pp. 870-882. Wolters Kluwer/Lippincott Williams & Wilkins, Philadelphilia, PA, 2012.+

4. Chen L, Pan Y, Zhang L, Wang Y, Weintraub N, Tang Y. Two-step protocol for isolation and culture of cardiospheres. Methods Mol Biol. 2013;1036:75-80.#

5. Chen Z, Li Y, Yu H, Shen Y, Ju C, Ma G, Liu Y, Kim I, Weintraub NL, Tang Y. Isolation of Extracellular Vesicles from Stem Cells. Methods in molecular biology (Clifton, N.J.). 2017; 1660:389-394.#

date of revision - augusta

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