STRATEGY FOR COMBATTING THE

RISE OF DRUG-RESISTANT

BACTERIA IN THE US

David Marash-Whitman11/20/13

KPC(Klebsiella

pneumoniaecarbapenemase)

18 infected patients

6 fatalities

complete drug resistance

persistent presence at

NIH center

THE PROBLEM

increased usage leadsto decreased future effectiveness

antibiotics are being used excessively

development of new antibioticsis expensive

finite source of future antibiotics

THE SOLUTION

promote conservative use of antibiotics

incentive to comply

remove barriers to compliance

THE SOLUTION

bioethical responsibility

timeliness affordability

THE SOLUTION

bioethical responsibility

timeliness affordability

THE SOLUTION

bioethical responsibility

timeliness affordability

THE SOLUTION

promote conservative use of antibiotics

increase incentive to comply

remove barriers to compliance

THE SOLUTION

Prove-It SepsisSeptifast Sepsitest

$50

6 hours

25 species

$75

3.5 hours

70 species

$125

<1 hour

345 species

THE SOLUTION

bioethical responsibility

timeliness affordability

THE SOLUTION

bioethical responsibility

timeliness affordability

OUTCOMES

accessibility of medical technology

reduction of inappropriateantibiotic prescriptions

SHORT TERMPREVENTION LONG TERM

general health

vaccination

development ofnew antibiotics

conservative useof antibiotics(in humans)(in animals)

development ofnew antimicrobial

therapies