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The ASHI Education Committee cordially invites you to attend ASHI’s Regional Education

Workshops this spring. The faculty is excited to have an opportunity to share their

expertise and experiences over a wide range of topics ranging from vaccine design to

opportunities in living organ donation.

The committee encourages you to actively participate in the workshop whether it’s a social

exchange at our Welcome Reception, presenting a case study, or sharing your thoughts in

our question-and-answer sessions. Regardless, our faculty debate is sure to get you

involved.

The host cities will provide a wonderful opportunity for attendees to get away from the

academic environment and kick back and enjoy the surroundings. Take advantage of our

mid-day break to explore the cities and sample the local cuisine. We hope you find the

workshops to be a rewarding and educational experience that you can share with your

colleagues upon your return to the lab.

On behalf of the faculty, I am honored to invite you to be a part of the 2009 Regional

Education Workshops.

Dean Sylvaria, BS, CHS

Chair, ASHI Education Committee

ASHI 2009 Regional Education Workshops

American Board of

Histocompatibility and

Immunogenetics (ABHI)

The American Board of Histocompatibility and Immunogenetics has approved the 2009 Regional Education Workshop content for a maximum of 12.5 contact hours or1.875 continuing education credits (CEC) applicable for Certified HistocompatibilityTechnologist (CHT), Certified Histocompatibility Specialist (CHS), and ABHI Diplomates.

A Syllabus and a list of commercial contributors will be available at the workshops.

Travel Information

Airline

AirTran Airways is the official carrier for the 2009 Regional Education Workshops.Contact Airways EventSavers Desk at (866) 68EVENT to make your reservation. Pleaserefer to the assigned AirTran Airways Discount Code for each city to receive a 10 percentdiscount off the lowest applicable published airfare.

AirTran Airways Discount Codes

New Orleans, LA: MSY031909Los Angeles, CA: LAX042309Baltimore, MD: BWI061109

Rental Car

Avis is the official rental car supplier for the 2009 Regional Education Workshops. Forreservations call Avis directly (800) 331-1600 and refer to the Avis Worldwide Discount(AWD) Number J869090.

Hotel Accommodations

Hotel reservations must be made directly with each hotel by calling the toll-free telephonenumber provided for each workshop. Please mention the ASHI RegionalEducation Workshop to receive the discounted rate. A credit card or onenight’s deposit may be required to guarantee your reservation. Please DO NOT sendyour hotel request to the ASHI Office.

Welcome Reception

On Thursday evening, join fellow meeting participants and national faculty members asASHI kicks off each Regional Education Workshop with refreshments and hors d’oeuvresprovided by ASHI.

Case Study Contest

New this year... audience-awarded Case Studies! Case studies will be accepted into the contest on a first-come, first-served basis. A maximum of eight case studies will be scheduled for presentation, per meeting. The three highest-ranking case studies per meeting will receive a $50 American Express Gift Card. Case studiessubmitted and presented will be peer reviewed and winners will be announced prior to thedebate on Saturday afternoon. Please review the submission deadlines below and submitall case studies via e-mail to Dean Sylvaria at [email protected].

• First-come, first-served entry, maximum of eight case studies accepted per meeting• Winners receive $50 American Express Gift Card• Open to technologists and supervisors• Prepare a 10-minute PowerPoint presentation• Winners will be acknowledged in the ASHI Quarterly

Submission Deadlines

New Orleans: Monday, March 2nd

Los Angeles: Monday, March 30th

Baltimore: Monday, May 18th

DEBATE

Audience participation required! Enjoy a lively debate among this year’s nationalfaculty and do not forget to pick a side! Audience members will be prompted to choose aside as arguments are heard and challenged.

Michael D. Gautreaux, PhD, D(ABHI)

Wake Forest University Health Sciences

Michael D. Gautreaux, PhD, D(ABHI) is an Associate Professor in the Department of General Surgery at Wake Forest UniversitySchool of Medicine. Dr. Gautreaux is currently the director of theHLA/Immunogenetics Laboratory at Wake Forest University/BaptistMedical Center.

Dr. Gautreaux is an active member of the American Society for Histocompatibility andImmunogenetics (ASHI). He served two years as chair of the ASHI Bylaws Committee, as a member of the International Affairs, and is currently the chair of the Director’s AffairsCommittee. In addition, Dr. Gautreaux is a co-chair of the ASHI Accreditation ReviewBoard, which accredits HLA laboratories nationally and internationally. He is a past member of the board of directors for Life Point of South Carolina, the OPO for that state.Currently, he is serving as the Region 11 representative to the UNOS/Organ Procurementand Transplantation Network’s Histocompatibility Committee and is a member of the UNOSRegion 11 Nominating Committee.Dr. Gautreaux has a special interest in studying anti-HLA antibodies and their role in healthand disease. He has given presentations at several national and international symposia andhas published in several peer-reviewed journals, such as Infection and Immunity, Biology ofBlood and Marrow Transplantation, Clinical Orthopaedics and Related Research,Transplantation, and Human Immunology.

Mary S. (Susie) Leffell, PhD,

D(ABHI), D(ABMLI)

Johns Hopkins University

Mary S. (Susie) Leffell, PhD, is Professor of Medicine and Director ofthe Immunogenetics Laboratory of the Johns Hopkins University Schoolof Medicine. Dr. Leffell has been an active participant in clinical histo-compatibility and transplantation for close to 30 years. She has been

involved in numerous ASHI activities, having served as Chair of the AccreditationCommittee, and Vice President and President of the Society. She was a principal player inthe original application to the Centers for Medicare/Medicaid Services (CMS), which ledto ASHI’s Accreditation Program being awarded deemed status and she has continued toserve as a liaison to CMS for ASHI. She received ASHI’s Distinguished Service Award in2003 in recognition of these contributions. She has contributed to the development of trans-plantation policies through her service in various capacities to the national OrganProcurement and Transplantation Network/United Network for Organ Sharing (OPTN/UNOS), which have included two terms on the board of directors, serving as Chair of theHistocompatibility Committee, and as a member on the Kidney Transplant and KidneyAllocation Review committees, which are developing a proposal for a revised, nationalrenal allocation system. For the past four years, she has served as a member of the AdvisoryCommittee on Organ Transplantation to the Secretary of the Department of Health andHuman Services. Her research contributions have been in humoral sensitization andimmunogenetic population studies involving HLA alleles and haplotypes, KIR, cytokine alle-les, and minor histocompatibility antigens.

National Faculty Members

David Senitzer, PhD, D(ABHI),

D(ABMLI)

City of Hope National Cancer Center

David Senitzer has been the HLA Laboratory Director at the City ofHope for more than 14 years. He graduated from the City College ofNew York with a BS in Biology, and Louisiana State University with aPhD in Microbiology. After serving a postdoctoral fellowship in

Immunochemistry at Columbia University College of Physicians and Surgeons he joined thefaculty at the Medical School of Ohio (MCO) as an Assistant Professor of Microbiology. Hestarted the HLA Laboratory at MCO, and was its Director for 13 years. He moved to south-ern California to work at the City of Hope, which is one of the largest hematopoietic celltransplant centers in the country, performing more than 200 allogeneic transplants per year.He has served on the ASHI Director Training Review Committee, both as a member and asthe Chairperson. His clinical research interests are in the development of NK cell interactionsin HCT. In the past few years he has been especially interested in KIR matching, and itseffects on the outcome of HCT.

Anajane Smith, MA

Seattle Cancer Care Alliance

Anajane Smith received her BA and MA in Immunology from theUniversity of California, Berkeley, with departmental honors and PhiBeta Kappa. Anajane joined the Clinical Immunogenetics Laboratory(CIL) at Fred Hutchinson Cancer Research Center to work on HLAmolecular typing prior to the 10th International Histocompatibility

Workshop of 1987, the first of the IHWS that included HLA typing by molecular methods.Anajane oversaw the implementation of DNA-based test technology in the CIL, and man-aged the subsequent evolution in molecular test technology and procedures for clinical HLAtyping and engraftment monitoring. In 1998, Anajane was promoted to Manager of the CILand continues to serve in this capacity. She has presented workshops and abstracts at ASHIannual and regional meetings as well as internationally.

Andrea A. Zachary PhD, D(ABHI)

Johns Hopkins University

Andrea A. Zachary, PhD, D(ABHI), is a charter member of ASHI andhas been active in clinical histocompatibility and immunogenetics formore than 35 years, starting as a technologist and rising to Director ofthe Immunogenetics Laboratory of the Cleveland Clinic Foundation.She is currently Professor of Medicine and Director of the

Immunogenetics Laboratory of the Johns Hopkins University School of Medicine, followingher tenure (1991-94) as Chief of the Transplantation Section of NIAID, NIH. She has servedASHI in many capacities, notably twice having been instrumental in the development andimplementation of the Accreditation Program. She served as the first Chair of Accreditation(1986-88), when the program was revised to facilitate the evaluation of laboratories forUNOS, and then served as the first Program Director of the Accreditation Review Boardwhen the program was revised in 1998. She was a member of the ASHI Council for 10years, holding several offices, including Vice President and President. She was recognizedfor her contributions to ASHI in 2000 with the Distinguished Service Award.

Thursday

6:00 pm – 7:00 pm Registration

8:00 pm – 9:00 pm Welcome Reception

Hors d’oeuvres will be served

Friday

7:30 am – 6:00 pmVendor Room Open

Morning Program

7:00 am – 8:00 am Registration

7:30 am – 8:00 am Continental Breakfast

8:00 am – 9:00 am Immunogenetics Applied to Vaccine Design

Mary S. Leffell, PhD, D(ABHI), D(ABMLI)

Andrea A. Zachary, PhD, D(ABHI)

9:00 am – 10:00 am TRALI

Michael D. Gautreaux, PhD, D(ABHI)

10:00 am – 10:45 am Vendor Innovative Technology Presentations

10:45 am – 11:00 am Beverage Break with Vendors

11:00 am – Noon Somatic Mutations in HLA Genes

Anajane Smith, MA

Noon – 1:30 pm Lunch on Own

Afternoon Program

1:30 pm – 2:30 pm Monitoring Engraftment

Post Hematopoietic Stem Cell Transplantation

David Senitzer, PhD, D(ABHI), D(ABMLI)

2:30 pm – 3:15 pm Vendor Innovative Technology Presentations

3:15 pm – 3:30 pm Beverage Break with Vendors

3:30 pm – 4:30 pm Using Real Data for a Virtual Crossmatch

Mary S. Leffell, PhD, D(ABHI), D(ABMLI)

Andrea A. Zachary, PhD, D(ABHI)

4:30 pm – 5:00 pm Vendor Innovative Technology Presentations

5:00 pm – 5:45 pm Case Study Presentations

ASHI 2009 Regional Education Workshop Preliminary Program

Saturday

8:00 am – 12:30 pmVendor Room Open

Morning Program

7:00 am – 8:00 am Registration

8:00 am – 8:30 am Continental Breakfast

8:30 am – 9:30 am HLA Molecular Typing: Technologies,

Ambiguities, Applications

Anajane Smith, MA

9:30 am – 10:30 am Role of Killer Immunoglobulin-like Receptor Genes

and/or Their Ligands in Hematopoietic Stem Cell

Transplantation

David Senitzer, PhD, D(ABHI), D(ABMLI)

10:30 am – 10:45 am Beverage Break with Vendors

10:45 am –11:45 am Antibodies, What’s New and Clinically Significant

Michael D. Gautreaux, PhD, D(ABHI)

11:45 am – 12:45 pm Opportunities for Living Donor Transplants: Paired

Donor Exchanges and/or Desensitization

Mary S. Leffell, PhD, D(ABHI), D(ABMLI)

Andrea A. Zachary, PhD, D(ABHI)

12:45 pm – 1:45 pm Lunch on Own

Afternoon Program

1:45 pm – 2:45 pm Stories of Donation

Experience From Donor/Recipient

2:45 pm – 3:30 pm Case Study Presentations

3:30 pm – 3:45 pm Beverage Break

3:45 pm – 4:45 pm Award Case Study Winners (Top 3)

National Faculty

Debate: National vs. Regional Paired Exchange

Michael D. Gautreaux, PhD, D(ABHI)

Mary S. Leffell, PhD, D(ABHI), D(ABMLI)

Andrea A. Zachary, PhD, D(ABHI)

ASHI 2009 Regional Education Workshop Preliminary Program

March 19 - March 21, 2009

Le Pavillon Hotel

833 Poydras Street

New Orleans, LA 70112

National Faculty Members

Michael D. Gautreaux, PhD, D(ABHI)

Mary S. Leffell, PhD, D(ABHI), D(ABMLI)

David Senitzer, PhD, D(ABHI), D(ABMLI)

Anajane Smith, MA

Early Registration Deadline:

Friday, March 6, 2009

Discount ASHI Hotel Rate: $ 159+tax

Hotel Reservation Deadline:

Monday, Feb. 23, 2009

Toll Free Reservations: (800) 535-9095

Hotel Telephone: (504) 581-3111

Hotel Fax: (504) 620-4130

Le Pavillon New Orleans French Quarter Hotel piques theimagination in a way that even the emperor himself wouldapplaud. Located in the heart of downtown New Orleans,Hotel Le Pavillon sits adjacent to the historic French Quarter,only five short blocks to the celebrated music clubs ofBourbon Street, and the famous restaurants and antiqueshops of Royal Street.

Local Transportation Information

Airport Shuttle is the Official Ground Transportation Providerfor the Louis Armstrong New Orleans International Airport.Shared van service for 1 passenger, round trip is $30, oneway is $15. Call (866) 596-2699 or (504) 522-3500 formore details or to make a reservation.

A taxicab ride costs $28 from the airport to the CentralBusiness District (CBD) for one or two persons and $12 (perpassenger) for three or more passengers. Pick-up is on thelower level, outside the baggage claim area. There may bean additional charge for extra baggage. $1 fuel surchargeadded to total fare.

April 23 - April 25, 2009

Westin Bonaventure Hotel & Suites

404 South Figueroa Street

Los Angeles, CA 90071

National Faculty Members

Michael D. Gautreaux, PhD, D(ABHI)

Mary S. Leffell, PhD, D(ABHI), D(ABMLI)

David Senitzer, PhD, D(ABHI), D(ABMLI)

Anajane Smith, MA

Andrea A. Zachary PhD, D(ABHI)

Early Registration Deadline:

Friday, April 10, 2009

Discount ASHI Hotel Rate: $ 159+tax

Hotel Reservation Deadline:

Tuesday, March 24, 2009

Toll Free Reservations: (800) 937-8461

Hotel Telephone: (213) 624-1000

Hotel Fax: (213) 612-4800

ASHI Reservations Web site:

www.starwoodmeeting.com/Book/ashi09

In the heart of Los Angeles’ downtown financial district, thelandmark Westin Bonaventure Hotel & Suites is ideally locat-ed. Guests have easy access to cultural and business cen-ters, as well as nearby beaches, the Los Angeles ConventionCenter, and the Staples Center.

All of your needs can be met in the central atrium, whichhouses 42 restaurants and shops. Take time for your mindand body in the state-of-the-art WestinWorkout® Gym, and

then relax at the revolving cocktail lounge with panoramicviews, BonaVista.

Each of the recently renovated guest rooms was designed tosoothe you with floor-to-ceiling views of Los Angeles, as wellas the signature Heavenly Bed® and Heavenly Bath®.

Local Transportation Information

Thanks to SuperShuttle, getting to and from LAX is easier thanever. For information on service to/from all SouthernCalifornia counties, phone (310) 782-6600 (Reservations).One-way fare using SuperShuttle from LAX to the WestinBonaventure Hotel & Suites is $16.

Taxis can be found curbside on the Lower/Arrival Levelislands in front of each terminal under the yellow sign indicating TAXIS. Passengers will be presented with a ticketstating typical fares to major destinations. A taxi ride usingYellow Cab from LAX to the Westin Bonaventure Hotel &Suites is $46.50 (flat rate).

June 11- June 13, 2009

Sheraton Baltimore City Center

101 West Fayette Street

Baltimore, MD 21201

National Faculty Members

Michael D. Gautreaux, PhD, D(ABHI)

Mary S. Leffell, PhD, D(ABHI), D(ABMLI)

David Senitzer, PhD, D(ABHI), D(ABMLI)

Anajane Smith, MA

Andrea A. Zachary PhD, D(ABHI)

Early Registration Deadline:

Friday, May 29, 2009

Discount ASHI Hotel Rate: $ 159+tax

Hotel Reservation Deadline:

Tuesday, May 12, 2009

Toll Free Reservations: (800) 325-3535

Hotel Telephone: (410) 752-1100

Hotel Fax: (410) 385-6865

ASHI Reservations Web site:

http://www.starwoodmeeting.com/StarGroupsWeb/res?id=0812152980&key=5520B

Sheraton Baltimore City Center Hotel offers a great locationfor business and pleasure. It is directly across from the 1stMariner Arena and Baltimore’s fun, beautiful, historic InnerHarbor is only three blocks away.

You’ll feel right at home in the spacious guest rooms andsuites. A full fitness center and outdoor pool make it easy tounwind. The award-winning Shula’s Steak House and Shula’s2 serve up sizzling fare in a relaxed, comfortable setting.

Ready to see the sights? Enjoy a vibrant neighborhood alive with activities, including the Hippodrome Theatre, CamdenYards, Ravens Stadium, National Aquarium, and MarylandScience Center. You'll find a wide variety of top restaurants and shops to explore.

Local Transportation Information

Thanks to SuperShuttle, getting to and from BWI is easierthan ever. For information on service to/from Baltimore’sInner Harbor Hotel District, Baltimore City, and Baltimore,Prince George, Montgomery, Anne Arundel Counties, andAnnapolis as well as Northern Virginia, phone (800) BLUEVAN (258-3826). One-way fare using SuperShuttle fromBWI to the Sheraton Baltimore City Center is $21.

The BWI taxi stand is located just outside of the baggageclaim area of the Lower Level of the BWI Marshall AirportTerminal. Please note that this service is available from BWIonly. For cab service to BWI, please consult your local cab company. One-way fare from BWI to Baltimore is $32 (estimate as of August 2007). BWI taxicabs are prohibited from charging flat rates.

New Orleans Campus

Los Angeles Campus

Baltimore Campus

HOUSING INFORMATION

ASHI Regional Education Workshops

Registration Form

Please submit your registration form to the ASHI executive office (see address below).

To guarantee obtaining the discounted rate, please note the early registration deadline for each workshop.

Please print clearly: This information will be used to print your badge.

First Name: Last Name:

ASHI Membership Identification Number:

Institution:

Address:

City: State: Zip: Country:

Daytime Phone: Fax:

E-mail address: �� Check here if Meeting Sponsor

Please indicate any special needs:

If you wish to become a member of ASHI, please visit the ASHI Web site, www.ashi-hla.org, to download a membership application.

Please note: An additional $50 will apply to all registrations received after the early registration deadline dates provided.

Method of Payment:

� Check / Money Order � VISA � MasterCard � American Express

Card Number: Expiration Date:

Full Name on Credit Card: Signature of Attendee: (required)

All funds should be in U.S. currency and drawn on a U.S. bank. If you send a check drawn on a non-U.S. bank, enclose $25 additional for processing

fees. Make all checks or money orders out ASHI.

Cancellation Policy: Written cancellation of registration must be received one month prior to the meeting. There will be no refund for can-

cellations made after that or for “no shows.” There will be a $25 processing fee for all cancellation requests. Substitutions of registrants are

permitted. Refunds will be processed after the meeting.

Make all checks payable to:

ASHI • 15000 Commerce Parkway, Suite C • Mount Laurel, NJ 08054

Incomplete registrations or registrations received without payment will not be processed.

For any questions contact ASHI Executive Office Registration Department

Phone: 856-638-0428 • Fax: 856-439-0525

Early Registration Fees:

(refer to the dates provided under each workshop)

� Full Workshop

Member: $250/Non-Member: $275

�Welcome Reception (FREE)

� Single Day: Friday

(March 20th

, April 24th

or June 12th

)

Member: $199/Non-Member: $225

� Single Day: Saturday

(March 21st

, April 25th

or June 13th

)

Member: $199/Non-Member: $225

Late Registration Fees:

� Full Workshop

Member: $300/Non-Member: $325

�Welcome Reception (FREE)

� Single Day: Friday

(March 20th

, April 24th

or June 12th

)

Member: $249/Non-Member: $275

� Single Day: Saturday

(March 21st

, April 25th

or June 13th

)

Member: $249/Non-Member: $275

Total Amount for Registration:

$

Please select the Regional Education Workshop you wish to Attend:

� New Orleans, Louisiana

March 19 - 21, 2009

Early Registration Deadline:

Friday, March 6

� Los Angeles, California

April 23 – 25, 2009

Early Registration Deadline:

Friday, April 10

� Baltimore, Maryland

June 11 - 13, 2009

Early Registration Deadline:

Friday, May 29

Please Check Any Box Which Applies to You:

Didactic Part Week #1

Genomic Medicine for Complex Diseases. Introduction to Immunogenetics . The Human MHC(HLA) Complex: Class I and Class II Regions. Molecular Diagnosis and Prediction of MendelianDiseases and Diagnosis of Congenital Malformations. The MHC in Cellular Interactions: AntigenPresentation and Biosynthesis of MHC Molecules. The MHC and Disease Associations:Molecular Mechanisms of MHC Associations in Autoimmune Diseases. Relevance ofInflammation in the Pathogenesis of Neurocysticercosis. Molecular Mechanisms of HLAAssociated Diseases. Cellular techniques and Their Use to Monitor Solid Organ Transplants.Methods for Isolation of Cell-Subpopulations: HLA Typing by Microlymphocytotoxicity. Overviewon the Aspects of Accreditation of a Laboratory of Immunogenetics in Latin America. Methods forMolecular Typing of Class I and Class II Genes . Immunological Mechanisms of Solid OrganTransplant Rejection. Current Methodology and Clinical Significance of Cross Matching for SolidOrgan Transplants. Mechanisms of Injury of HLA Antibodies on the Transplanted Organ afterImmunization. Identification of the Antibody in Transplanted Patients. Monitoring Tests Used afterTransplantation for Assessing the Immunological Status of the Patient .Clinical Significance of HLAantibodies in Renal Patients Post-Transplantation and in Chronic Rejection. Cellular Monitoring ofSolid Organ Transplants. Impact of the Different Clinical Protocols in Laboratory Testing. Killer-Cell Immunoglobulin-Like Receptors. Genetic Diversity of KIR-HLA Combinations and Relevancein Human Disease. Typing Methods for NK Cell Receptors and HLA ligands. Origin andEvolution of NK Cell Receptors. Antibodies Vs. HLA and TRALI in Transfusion Refractory States.Clinical Assessment of The Patients After Transplanting Mismatched Kidneys, Ethical and LegalAspects of Solid Organ Transplantation. Cell Therapy and Heart Transplantation. Immunology ofAllogeneic Bone Marrow Transplants . Worldwide Impact of Unrelated Bone Marrow DonorRegistries: Current Status of The Mexican Bone Marrow Registry (DONORMO). BiologicalImpact of Genetic Diversity in Populations. Molecular Anthropology: Lessons of Mexican andOther American Indians. Search Strategies to Get an Unrelated Bone Marrow Donor.Characteristics of an Umbilical Cord Blood Bank. Genetic Diversity in the Minorities of The USAand Its Impact in Transplantation.

Laboratory Part Week #1

Mixed Lymphocyte Culture. Methods of Isolating of Lymphocyte Subtypes: Nylon,Monoclonal, Magnetic-Beads, HLA Typing Using Fluorescence . HLA Typing byMicrolymphocytotoxicity. Cross-Matching with & without DTT and Anti-IgG. Antibody Detection usingELISA . Antibody Screening Using Luminex. Antibody Identification using Luminex.

Didactic Part Week #2

From Genetics to Pharmacogenomics in Medicine. Replication, Translation and ProteinBiosynthesis .Molecular Epidemiology: A Tool of Great Impact in Medicine . . Molecular Basis ofAlzheimer’s Disease. Some Important Tools for Genetic Analysis. Genetic Organization of theMHC, Structure, Expression and Function . Polymorphism and Evolution of MHC Genes.Immunobiology of Minor Histocompatibility Antigens. Introduction to KIR Genes. ImmuneResponse Against Pathogens. Technology Used for Human Identification. Real-Time PCR.Application in Immunogenetics. Immunologic Evasion Mechanisms Used by Viruses. PopulationGenetics and Infections. SIV as a Model of Investigation of a Vaccine Against AIDS. Importanceof KIR Genes in Transplantation, in Autoimmune and Viral Diseases. Contribution of DifferentMHC Genes to the Outcome of Bone Marrow Transplantation Survival Rates among UnrelatedIndividuals . Molecular Mechanisms of HLA Association in Psoriasis: MHC and KIR Genes. Non-MHC Factors Affecting Bone Marrow Transplantation. MHC criteria for MHC selection for bonemarrow transplantation. HLA Peptide Binding Prediction as an Important Tool to Design a VaccineAgainst AIDS. Genetics and Functional Genomics in Cancer. New ImmunotherapeuticProcedures for the Treatment Using HSCT. The Future of Umbilical Cord Stem CellsTransplantation; an Alternative for Transplantation . Ethical Aspects, Myths and Reality of its Use.HLA-Epitopes. NK Cells and KIR receptors. Genetics and polymorphism of KIR genes. Their rolein disease and in Transplantation. Immunotherapy. Minor Antigens. Structure and function ofmHA. The role of mHA in bone marrow transplantation. Molecular Mechanisms of HLAAssociated Infectious Diseases: Tuberculosis and Leprosy . Theory and Practical Basis of PCR .Typing of PCR Products; Sequence-Specific Amplification; Dot Blot; Reverse Dot-Blot; PCR-RFLP;Molecular Methods of Class I Typing. Sequence-Based Typing of HLA Genes. Microsatellites,STRs and Minisatellites; Gene-Scan: Uses and Approaches: Gene Identity and Paternity Testing.Basic Concepts of Sequencing . Real-Time PCR. Its use in Immunogenetics.

Laboratory Part Week #2

Extraction and Purification of DNA. Class II Generic PCR. PCR for DRB1. Sequence-BasedTyping (SBT) . PCR-SSOP (Chemiluminescence, Demonstration only); Allele Specific Amplificationfor Class I and Class II Genes (PCR-SSP). Reverse-Dot Blot Using Strips (Demonstration only).Reverse Dot-Blot using Luminex. Real Time PCR. Gene-Scan (STRs).

TEN DIFFERENT TECHNICAL LUNCHES WILL BE OFFERED BY DIFFERENT COMPANIES

2009 Mexico Workshop

28th Current Course on Immunogenetics:

Didactic and Laboratory Parts

Meeting Dates: July 27 – July 31, 2009

24th Current Course on Molecular Genetics.

Didactic and Laboratory Parts

Meeting Dates: August 3 – 7, 2009

The workshop will be presented part in Spanish and part in English. The invited speakers fromabroad will present their lectures in English. Continuing Education Credits will be provided by theAmerican Board of Histocompatibility and Immunogenetics (ABHI) for attendance at this work-shop, with the Academic accreditation of The Faculty of Medicine, UNAM (UniversidadNacional Autonoma de Mexico). It is accepted as an optional subject for PhD programs inMexican and Latinamerican Universities.

Director: Clara Gorodezky, PhD, DSc

E-mail address: [email protected]@fundacioncompartevida.org.mx

Organized by: Department of Immunology and Immunogenetics

of Instituto de Diagnostico y Referencia

Epidemiologicos, Secretary of Health (InDRE),

Mexico City

Under the Auspices of:

The American Society for Histocompatibility and Immunogenetics (ASHI)

The American Board of Histocompatibility and Imunogenetics (ABHI)

Fundacion Comparte Vida, A.C.

Registration Information:

Department of Immunology and Immunogenetics, InDRE

Carpio #470 – 1st Floor

Mexico D.F., 11340 MEXICO

Phone: (+52 55) 5341-4569; 4342-7557

Fax: (+52 55) 5341-4418

Registration fees:

Didactic part only $750.00 each course

Didactic and laboratory parts $950.00 each course

*Please note that currency is listed in US dollar amounts.