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Deep mycosis

 MICETOMA = MADURA MICOSIS = MICETOMA = MADURA MICOSIS =

 M.FOOT  M.FOOT 

CHROMOMYCOSIS =CHROMOMYCOSIS =

CHROMOBLASTOM YCOSIS CHROMOBLASTOM YCOSIS 

 ACTINOMYCOSIS  ACTINOMYCOSIS 

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MICETOMA =MICETOMA =

MADURA MICOSIS =MADURA MICOSIS =

M.FOOT M.FOOT 

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• Chronic localized sub cutisChronic localized sub cutis

infectioninfection fascia, muscle,fascia, muscle,bone destruction.bone destruction.

Caused by :Caused by :

• Genus actinomises, nocardia &Genus actinomises, nocardia &

streptomises; sp. madurello,streptomises; sp. madurello,

fialapora, sefalosporium.fialapora, sefalosporium.

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PredilectionPredilection• Foot, lower leg or hand, althoughFoot, lower leg or hand, although

head and bac may occur head and bac may occur 

Clinical featuresClinical features

• Painless nodul ! papules, drainingPainless nodul ! papules, drainingsinus tract ! local tissue swelling,sinus tract ! local tissue swelling,

chronic sinus formationchronic sinus formation•

"ater!painfull,when sinus tract are"ater!painfull,when sinus tract areemerge to the sin surfaceemerge to the sin surface

#$F.#$F. : sin trauma: sin trauma

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GranulesGranules 

• hite granulehite granule

• -ed granule-ed granule

•

lac granulelac granule

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• $ocardial$ocardial sulfa * //0sulfa * //0

• '.maduromicosis'.maduromicosis widewide

e1cisione1cision

%-)2%')$%%-)2%')$%

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CHROMOMYCOSIS CHROMOMYCOSIS  ==CHROMOBLASTOM YCOSIS CHROMOBLASTOM YCOSIS 

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P-)/#")C%#3$P-)/#")C%#3$

• foot, hand & gluteafoot, hand & glutea

Fungal infection through traumaFungal infection through trauma

mechanism 44 farmer mechanism 44 farmer 

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C"#$#C2" F)2%5-)0C"#$#C2" F)2%5-)0

• $odul$odul connecti6e tissue,connecti6e tissue,

6erucous at surface6erucous at surface

• Chronic, painlessChronic, painless

• FibrosisFibrosis elephantyasis.elephantyasis.

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)%#3"3G7

Fonsasea pedrosoi, F.compacta,Fonsasea pedrosoi, F.compacta,

Cladosporum arioniiCladosporum arionii

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• Potassium #odidePotassium #odide

•

2mfoterisin 2mfoterisin • 8etoconazole8etoconazole

•

#traconazole#traconazole• ide e1cisionide e1cision

%-)2%')$%%-)2%')$%

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ACTINOMYCOSIS

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• Actinomycosis→ chronic fungal infection with

granulomatous supurative lession

Et/ - Actinomyces Israeli

- Actinomyces Bovis

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1. ervico-facial Actinomycosis

!. "horacic Actnomycosis

#. A$%ominal Actinomycosis

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&I'IA& (EA")*E+

• "umor su$cutaneus, har% in consistency

lie $oar%

• &ocalie%

• +lowly progressif 

• ainles

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"*EA"0E'"

• enicillin → %rug of choice

1.12 unit/%ay 1-# %ays

• "etrasiclin

• +ulfa/DD+

• +urgery

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