Cellulaze™ is the only minimally invasive device for cellulite that results in a dramatically improved appearance that lasts after a single treatment.1 The science behind the innovation? Cynosure’s SideLaze™ proprietary fiber delivery system combined with a pulsed Nd:Yag 1440 nm wavelength.

The SideLaze fiber facilitates the most advanced cellulite treatment today. Designed with efficiency and effectiveness in mind, the side- firing SideLaze fiber provides physicians greater control to achieve an unprecedented level of results.

Delivering a Breakthrough in Cellulite Reduction.

Cellulaze incorporates Cynosure’s innovative Intelligent

Delivery Systems; ThermaGuide™ and SmartSense™.

ThermaGuide – integrated temperature sensing capabilities ensure safe temperature endpoints

SmartSense – motion control technology prevents hotspots and results in a more uniform treatment

Specifically target the structural issues underneath the skin that causes cellulite with the SideLaze delivery system.

Proven to increase the dermal layer by effectively stimulating the hypodermal junction to produce collagen – something only achievable with the combination of the SideLaze delivery system and the 1440nm wavelength

Treat even large areas in less than 1 hour with SideLaze efficiency

Due to the 1440nm wavelengths high affinity for water and lipid, it’s the only wavelength which produces a proper side firing effect through the generation of microbubbles at the fibertip.

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A Closer Look at SideLaze Technology

Cellulaze™ Cellulite Reduction Workstation

© 2012 Cynosure, Inc. Cynosure is a registered trademark of Cynosure, Inc. Be transformed, SideLaze, SmartSense, ThermaGuide and Cellulaze are trademarks of Cynosure, Inc. 921-0225-000 Rev.4 04/12

www.cynosure.com

An effective cellulite treatment must address all 3 structural issues: stiffened fibrous septae, bulging fat, and thin skin. Cellulaze is the first minimally invasive laser treatment which uses SideLaze technology to attack all three in just one treatment.

2 Estimated absorption based on main chromophores in tissue: Dermis contains approximately 70% water, Human fatty adipose tissue contains approximately 75% lipid and 20% water (Duck 1990, “Physical properties of tissue”, pp 320-328 London: Acedemic Press).

First laser energy is applied to adipose tissue, creating microbubbles at the tip of the SideLaze fiber to heat and disrupt the bulging pockets of fat. The laser energy is highly absorbed which efficiently breaks up the tissue and quickly disrupts the fat.

Next, the SideLaze fiber is used to thermally subcise the septal bands which pull down on the skin and create the dimpling effect. The release of the septae bands creates smoother looking skin.

Lastly, the SideLaze laser energy is directed upward to gently heat the skin. The heat coagulates the collagen and promotes the growth of new collagen.

Best results can be seen 3 months post procedure after new collagen is created, increasing skin thickness and elasticity.

1 DiBernardo, BE “Treatment of Cellulite with One Year Follow-up using a 1440nm pulse laser” Aesthetic Surgery Journal, March 2011

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The Cellulaze treatment with SideLaze technology allows you to focus your surgical skills on effectively treating the 3 structural issues that cause cellulite

Microbubbles formed at tip of the laser fiber