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Department of General Practice Aarhus University Diagnostic delay in cancer in primary health care Before and after introducing urgent referrals for suspected cancer Mette Bach Larsen 1,2 , Peter Vedsted 1 , Dorte Gilså Hansen 3 , Frede Olesen 1 1. The Research Unit for General Practice, Aarhus University. Bartholins Allé 2, DK-8000 Aarhus C. 2. Department of General Medicine, Aarhus University. Bartholins Allé 2, DK-8000 Aarhus C. 3. The Research Unit for General Practice, University of Southern Denmark. J.B Winsløvsvej 9A, DK- 5000 Odense C.

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Page 1: Department of General Practice Aarhus University Diagnostic delay in cancer in primary health care Before and after introducing urgent referrals for suspected

Department of General PracticeAarhus University

Diagnostic delay in cancer in primary health care

Before and after introducing

urgent referrals for suspected cancer

Mette Bach Larsen1,2, Peter Vedsted1, Dorte Gilså Hansen3, Frede Olesen1

1. The Research Unit for General Practice, Aarhus University. Bartholins Allé 2, DK-8000 Aarhus C.

2. Department of General Medicine, Aarhus University. Bartholins Allé 2, DK-8000 Aarhus C.

3. The Research Unit for General Practice, University of Southern Denmark. J.B Winsløvsvej 9A, DK-5000 Odense C.

Page 2: Department of General Practice Aarhus University Diagnostic delay in cancer in primary health care Before and after introducing urgent referrals for suspected

Department of General PracticeAarhus University

Outline

Background

Methods

Results

Conclusion

Page 3: Department of General Practice Aarhus University Diagnostic delay in cancer in primary health care Before and after introducing urgent referrals for suspected

Department of General PracticeAarhus University

Urgent referrals for suspected cancer Introduced in Denmark 1 April 2008

Head and neck cancer

Colorectal cancer

Lung cancer

Breast cancer

Aim

to reduce processing-times, in particular to reduce referral time, obtain faster diagnosing and quick onset of treatment 

Page 4: Department of General Practice Aarhus University Diagnostic delay in cancer in primary health care Before and after introducing urgent referrals for suspected

Department of General PracticeAarhus University

Reasoned suspicion Colon cancer as an example

Main principle

All patients aged 40 years or older with symptoms of bleeding, longterm change in bowel habits or significant worsening in general condition

High-risk patients

Above mentioned symptoms and disease in first degree relatives

Page 5: Department of General Practice Aarhus University Diagnostic delay in cancer in primary health care Before and after introducing urgent referrals for suspected

Department of General PracticeAarhus University

Fast track diagnosisColon cancer as example

Weekday no. Procedure0 Referral received from GP

Triage and referral letter to patient5 Sigmoidoscopy (and rectoscopy if needed)

Informing the patient about the plan for fast track 7 Chest x-ray and CT scan of the abdomen8 Radiological diagnosis9 Preliminary examination by medical specialist

Information on diagnosis and treatmentInformed consent to treatmentDate of operationPreoperative nurse consult

15 Admission16 Operation

Page 6: Department of General Practice Aarhus University Diagnostic delay in cancer in primary health care Before and after introducing urgent referrals for suspected

Department of General PracticeAarhus University

Aim of this study

First symptom

First contact with the GP

Initiation of investigation of cancer-related

symptoms

Referral to hospital

First in-hospital

visit

Diagnosis / referral to treatment

Initiation of treatment

Patient delay Doctor delay System delay

Diagnostic delay Treatment delay

Diagnostic delay Primary Health Care

Sektor

System delay Secondary Health Care

Page 7: Department of General Practice Aarhus University Diagnostic delay in cancer in primary health care Before and after introducing urgent referrals for suspected

Department of General PracticeAarhus University

Methods

Cross-sectional study of 7,080 incident cancer patients

Questionnaires to the patients’ GPs

Inclusion before and after introduction of urgent referrals for suspected cancer

Patients dichotomised into two groups with or without access to fast track diagnosis

Page 8: Department of General Practice Aarhus University Diagnostic delay in cancer in primary health care Before and after introducing urgent referrals for suspected

Department of General PracticeAarhus University

FlowchartIncident cancer patients

Before GP confirmation: N=8118

Previously cancer diagnosis (n=173)

No cancer (n=131)

Not incident (n=704)

No inclusion diagnosis (n=17)

More than one cancer diagnosis (n=13)

Patients eligible for inclusionAfter GP confirmation: N=7080

Patient refusing to participate (n=20)

GP refusing to participate (n=29)

Non-responders (n=1153)

Completed questionnairesN=5878 (response rate: 83%)

Complete data from first visit to referral n= 4201 (59%)

Page 9: Department of General Practice Aarhus University Diagnostic delay in cancer in primary health care Before and after introducing urgent referrals for suspected

Department of General PracticeAarhus University

ResultsDiagnoses without fast track

Median 75% perc. 90% perc.4 days 23 days 76 days

010

020

030

040

0D

ela

y in

days

0 200 400 600 800 1000Patients

Delay over 1 year is set to 365 days

Before fast track diagnosisDiagnostic delay in primary health care: diagnoses without fast track

Median 75% perc. 90% perc.3 days 20 days 66 days

010

020

030

040

0D

ela

y in

days

0 200 400 600 800 1000Patients

Delay over 1 year is set to 365 days

After fast track diagnosisDiagnostic delay in primary health care: diagnoses without fast track

Page 10: Department of General Practice Aarhus University Diagnostic delay in cancer in primary health care Before and after introducing urgent referrals for suspected

Department of General PracticeAarhus University

ResultsDiagnoses with fast track

Median 75% perc. 90% perc.0 days 13 days 56 days

010

020

030

040

0D

ela

y in

days

0 200 400 600 800 1000Patients

Delay over 1 year is set to 365 days

Before fast track diagnosisDiagnostic delay in primary health care: diagnoses with fast track

Median 75% perc. 90% perc.0 days 12 days 50 days

010

020

030

040

0D

ela

y in

days

0 200 400 600 800 1000Patients

Delay over 1 year is set to 365 days

After fast track diagnosisDiagnostic delay in primary health care: diagnoses with fast track

Page 11: Department of General Practice Aarhus University Diagnostic delay in cancer in primary health care Before and after introducing urgent referrals for suspected

Department of General PracticeAarhus University

ResultsDelay < 30 days

80-85% had a delay less than 30 days

No significant change after introducing fast track

Page 12: Department of General Practice Aarhus University Diagnostic delay in cancer in primary health care Before and after introducing urgent referrals for suspected

Department of General PracticeAarhus University

Conclusion

Overall diagnostic delay in primary health care is short

Significant wait for 15-20% of the patients

No effect of fast track on diagnostic delay in primary health care

Page 13: Department of General Practice Aarhus University Diagnostic delay in cancer in primary health care Before and after introducing urgent referrals for suspected

Department of General PracticeAarhus University

Further research

Further research on why 15-20% of the patients are waiting 1 month or more

Further research on the effects of fast track

Fast track diagnosis vs. conventional diagnosis

How to handle patients with uncharacteristic symptoms

Page 14: Department of General Practice Aarhus University Diagnostic delay in cancer in primary health care Before and after introducing urgent referrals for suspected

Department of General PracticeAarhus University

Thank you for your attention!

[email protected]

The project is financed by the The Novo Nordisk Foundation