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Bachelor of Radiation Therapy Technology Revision. No. 1.3

SYLLABI

OF

BACHELOR OF RADIATION THERAPY TECHNOLOGY (BRTT)

AT

Department of Radiotherapy,Jawaharlal Nehru Medical College,

Aligarh Muslim UniversityAligarh, Uttar Pradesh

Revision HistoryRev No. Date

Document Created 1.0 2011

First revision 1.1 2013

Second revision 1.2 2016

Last Revision 1.3 2017

Aligarh Muslim University


2019-2020DEPARTMENT OF RADIOTHERAPY & CLINICAL ONCOLOGY

BACHELOR OF RADIATION THERAPY TECHNOLOGY (BRTT) 1ST YEAR

Course Title BRTT 1ST (Anatomy & Physiology)

Course Number : RT-101Credits :Course Category : BSCredits :Contact Hours (L-T-D) : 3-2-1 (60 Hrs)Type of Course : TheoryCourse Assessment :

Internal Assessment (1 Hour) (25%)Annual Examination (3 Hour) (75%)

Course Objectives

To impart the knowledge of Applied Anatomy & Physiology in the field of Radiotherapy Technician Course.

Course Outcomes

After completion of the course the students shall be able to understand:

.The basic knowledge of Anatomy and Histology, structure & function of cell, epithelial/muscular/skeletal and other connective tissues.

.Structure & function of bone, various classifications of bones, fractures of bones, and various movements of joints.

.Structure & function of different muscles of body.

.Structure & function of heart and major blood vessels of body, physiology of blood circulation,control of blood pressure and cardiac output.

.Structure & function of various lymphatic organs, lymph nodes and lymph vessels.

.Composition & function of blood, blood coagulation, and haemopoeisis.

.Structure & function of GI Tract, physiology of digestion and absorption of food.

.Structure & function of respiratory tract, physiology of respiration and gas exchange, respiratory disorders.



.Structure & function of Kidney and Urinary bladder, Mechanism of urine formation, disorders of kidneys.

.Structure & function of Endocrine glands, and hormones secreted by them.

.Structure & function of male and female reproductive system.

.Structure & function of Neurons, brain, spinal cord, Autonomic nervous system.

.Structure & function of Skin, sense organs and physiology of vision, hearing and olfaction.

.Surface Marking, Radiographic Anatomy and Topographical relation.

Syllabus

ANATOMYUnit 1: Introduction to Anatomy & Histology, Structure of cell, epithelial tissue, muscular tissue,nervous tissue.Unit 2: Skeletal System, Structure of bones, types of bones, Bones of cranium, face vertebralcolumn, upper and lower limbs, fracture of bones, various movements of joints.Unit 3: Muscular System, Structure and types of muscles in human body, important muscles andtheir group action.Unit 4: Circulation System, Structure of heart, names and position of main blood vessels.Unit 5: Lymphatic System, Lymph vessels, lymph nodes and lymphoid organs, their structure &functions.Unit 6 : Digestive systems. Parts of gastrointestinal tract and associated glands.Unit 7 : Respiratory System. Parts of Respiratory System.Unit 8 : Urinary System. Parts of Urinary System.Unit 9 : Endocrine System. Various endocrine glands. Thyroid. Parathyroid. Adrenal glandspituitary, pancreas, Thymus and sex glands.Unit 10 : Reproductive System. Male & female Reproductive organs.Unit 11 : Skin and sense organs. Eye, Ear, Nose. Taste BudsUnit 12 : Nervous System. Parts of brain, spinal cord, peripheral nerves.Unit 13 : Surface markings and topographical relations; radiography anatomy.

PHYSIOLOGYUnit 1 : Blood. Composition and function of blood, haemopesis, blood coagulation. Blood groups,body fluid.Unit 2 : Cardiovascular Systems. Circulation of blood. function of heart and blood vessels.Control of heart rate, pulse, regulation of blood pressure, blood volume.Unit 3 : Respiratory system. Function of lungs, mechanism of breathing and exchange of gases inthe lungs, regulation of respiration, Respiration disorder like anoxia, dyspnea cyanosis etc., artificialrespiration lung function tests.



Unit 4 : Digestive Systems. Digestion of food in mouth, stomach & small intestines. Absorption offood, function of liver function tests.Unit 5 : Excretory Systems. Structure & function of kidney and urinary bladder. Mechanism ofurine formation. disorders of kidney.Unit 6 : Endocrine Glands Functions of various endocrine glands and hormones secreted by them.Unit 7 : Reproductive Systems. Physiology & female reproductive organs.Unit 8 : Nervous System. Neurone & its function, function of central nervous system,Autonomous nervous system , physiology of vision, hearing & olfaction.

Suggested Readings/Text/References

Anatomy1. William Davis (P) understanding Human Anatomy and Physiology MC Graw Hill2. Chaursia –A Text book of Anatomy T.S. Ranganathan – A text book of Human Anatomy3. Fattana, Human anatomy (Description and applied) Saunder’s & C P Prism Publishers,Bangalore – 19914. ESTER . M. Grishcimer, Physiology & Anatomy with Practical Considerations, J.P. LippinCott.Philadelphia5. Anatomy and Physiology for Radiographers - C.A. Warrick6. Gray's anatomy Descriptive and applied - T.B. Johnstor.7. Foundation of Anatomy and Physiology - Ross and Wilson.8. An Atlas of Normal Radiographic Anatomy - Richard & Alvin9. Essentials of Human Anatomy - Russel

Physiology1. Guyton (Arthur) Text Book of Physiology. Latest Ed. Prism publishers2. Chatterjee(CC) Human Physiology Latest Ed. Vol-1, Medical Allied Agency3. Choudhari (Sujith K) Concise Medical Physiology Latest Ed. New Central Book,4. Ganong (William F) Review of Medical Physiology. Latest Ed . Appleton

Course OutcomesProgram Outcomes (POs)

a b c d e f g h i j k1 x x x2 x x3 x x4 x x5 x x x6 x x



Course Title : Biochemistry, Pathology & Microbiology

Course Code : RT-102

Contact Hours : 3 : 2 : 1 Lecture / Tutorial / Demonstration

Course assessment : sessional test and/or home assignment 25%; Annual exam 75%

Course objective : To understand the basics of Biochemistry, Pathology and Microbiology to first year students of Radiotherapy Technician

Course Outcomes :

After completion of the course the students shall be able to understand:1. The basic concepts of medical biochemistry including the knowledge of carbohydrates,

proteins, lipids, enzymes, vitamins and minerals acids and bases, standard solutions,units of measurement and specimen collection

2. The basics of pathology including the concepts of cell injury and adaptation, acute andchronic inflammation, disorders of vascular flow and shock, response to infection, and thehematopoetic and lymphoid system3. The basics of medical microbiology including introduction to microbiology, principles ofmicrobial control, immunology and virology

Biochemistry

Unit 1 : Carbohydrates : Glucose and Glycogen MetabolismUnit 2 : Proteins: Classification of proteins and functionsUnit 3 : Lipids: Classification of lipids and functionsUnit 4 : Enzymes: Definition – Nomenclature – Classification – Factors affecting enzyme activity– Active site – Coenzyme – Enzyme Inhibition – Units of enzyme – Isoeznzymes – Enzyme pattern in diseases.Unit 5 : Vitamins & Minerals: Fat soluble vitamins(A,D,E,K) – Water soluble vitamins – B-complex vitamins- principal elements(Calcium, Phosphorus, Magnesium, Sodium, Potassium, Chlorine and sulphur)- Trace elements – Calorific value of foods – Basal metabolic rate(BMR) – respiratory quotient(RQ) Specific dynamic action(SDA) – Balanced diet.Unit 6 : Acids and bases: Definition, pH, Henderson – Hasselbalch equation, Buffers, indicators, Normality, Molarity, Molality.Unit 7 : Distilled water : Types of distilled water plants, preparation & storage, Analytical balance: Principal, Working & maintenance ; Preparation of reagents : Formulation and preparationUnit 8 : Standard solutions: Various std. solutions used , their preparation ; storage of chemicals .Unit 9 : Units of measurements: S.I units: Definitions, conversions; Measurement of volume : Strength , Normality.Unit 10 : Specimen collection : Pre-analytical variables , Collection of blood , Collection of CSF & other fluids, Urine collection, Use of preservatives, Anticoagulants

PathologyUnit 1 : Cell Injury And Adaptation: Causes of cell injury. Mechanism of cellinjury,ishaemic &



hypoxic injury, chemical injury, reversible injury, nercosis ,cellular adaptation of growth & differentiation, atrophy, hypertrophy, metaplasia, hyperplasia, classification of tumors , premalignant lesion, diagnosis of cancer.Unit 2 : Acute And Chronic Inflamation: Acute vascular changes. phagocytosis, Chemical mediators of inflammation. Definition and causes of chronic inflammation. Granulomatous inflammation, system manifestations of inflammationUnit 3 : Disorders Of Vascular Flow And Shock: Oedema, hyperemia or congestion, thrombosis,embolism. Infarction shock, Ischemia, Over hydration, dehydration.Unit 4 : The Response To Infection Categories of infectious agents, host barriers to infection, how disease caused, inflammatory response to infectious agentsUnit 5 : The Haematopoietic And Lymphoid System: Haemorrhage. various type of Anaemia, leakopenia, leakocytosis, bleeding disorders coagulation mechanism, maintenance of blood volume. Abnormalities of pH of blood.

MicrobiologyUnit 1 : Introduction To Microbiology: Discovery of micro organisms. Classification and general characteristics of microorganisms, nutritional requirements of Micro-organisms.Unit 2 : Principles Of Microbial Control: Sterilization, importance of sterilization in OT techniques various methods-physical UV radiation, alcohols and heavy metals, Autoclave structurefunctioning control and indicators.Unit 3 : Immunology: Antigen-antibody reaction anaphylaxis hypersensitivityUnit 4 : Virology Imp disease caused by different viruses of mode of infection

Reference BooksBiochemistry

1. Varley – Clinical chemistry2. TEITZ – Clinical chemistry3. Kaplan – Clinical chemistry4. Ramakrishna(S) Prasanna(KG), Rajna ® Text book of Medical Biochemistry Latest Ed Orient longman Bombay –19805. Vasudevan (DM) Sreekumari(S) Text book of Biochemistry for Medical students ,Latest Ed6. DAS(Debajyothi) Biochemistry Latest ED Academic, Publishers, Culcutta – 1992

Pathology1. Culling Histopathology techniques2. Bancroft Histopathology techniques3. Koss – cytology4. Winifred greg – Diagnostic cytopathology5. Orell – Cyto Pathology6. Todd & Sanford Clinical Diagnosis by laboratory method7. Dacie & Lewis – Practical Haematology8. Ramanic Sood, Laboratory Technology (Methods and interpretation) 4th Ed. J.P. Bros,

New Delhi –1996)9. Satish Gupta Short text book of Medical Laboratory for technician J.P. Bros, New Delhi –

199810. Sachdev K.N. Clinical Pathology and Bacteriology 8th Ed, J.P. Bros, New Delhi-1991.11. Krishna - Text book of Pathology, Orient Longman PVT Ltd.Microbiology



1. Anathanarayana & Panikar Medical Microbioloty2. Roberty Cruckshank – Medical Microbiology – The Practice of Medical Mircrobiology3. Chatterjee – Parasitology – Interpretation to Clinical medicine.4. Rippon – Medical Mycology5. Emmons – Medical mycology6. Basic laboratory methods in Parasitology, 1st Ed, J P Bros, New Delhi – 1997. Basic laboratory procedures in clinical bacteriology, 1st Ed, J P Brothers,New Delhi8. Medical Parasitology – Ajit Damle





Course Title : BASIC RADIOLOGICAL PHYSICS & MEDICAL PHYSICS


Course Category : BS

Contact Hours (L:T:D) : 3 : 2 : 1

Type of Course : Theory


Course objective :

To impart the knowledge of Physics applications in Medicine specially to Radiology & Radiotherapy

Course Outcomes :

After completion of the course the students shall be able to understand:1. The basic concepts of physics relevant for radiological physics like electricity, magnetism and

electromagnetic induction and their applications2. The basics of x-ray generators and x-ray production3. Radioactiity, Radioisotopes and their uses in medicine 4. The concepts of Measurement theory relevant for radiation measurements

SYLLABUS

Unit 1 : Basic concepts: Units and measurements -Force, work, power and energy-Temperature and heat-SI units of above parameters. Atomic structure-atom model-Nucleus-electronic configuration-periodic table - Constituents of atoms, atomic and mass numbers, electron shells, atomic energy levels, Nuclear forces, Nuclear energy levels. Isotopes - Ionization – Excitation - Binding energy - electron volt

Unit 2: Electricity and magnetism: Electricity:Electric charges, Coulomb’s law, Unit of charge - Electric potential, unit of potential -resistance, ohm’s law - electric current, unit, electric power, heating effects of current, Joule’s law -capacitance and capacitors, series and parallel connection of resistors, capacitors and inductors. Magnetism : Magnetic induction - magnetic properties – classification of materials, Hysteresis -magnetic effect of currentElectrical instruments : Galvanometer, Voltmeter, Ammeter.



Unit 3 : Electromagnetic Induction: Induced electro motive force, Faradays experiments, laws of electromagnetic induction, inductorcoil, solenoid coil, Self and mutual induction.

Unit 4 : Alternating current :Peak and RMS values, AC circuits with resistance, capacitance and inductance, total resistance in acircuit, Impedance, Choke coil, eddy current. Transformer - theory, design, losses – types oftransformers, auto transformer, high voltage transformer, electric power transmission, ACgenerator, commercial unit of electric energy consumption.

Unit 5 : Electromagnetic radiation : Quantum nature of radiation-mass energy equivalence- Fluorescence-electromagnetic spectrum, Energy quantization, Relationship between wavelengths, Frequency, Energy.

Unit 5 : X-rays : Thermionic Emission, History, Discovery of x-rays, properties-production, x-ray spectrum, bremsstrahlung and characteristic x-rays- X-ray tube; Coolidge tube, tube design, line focus principle, space charge effect, Modern x-ray tubes; stationary anode, rotating anode, grid controlled x-ray tubes, heel effect, off focus radiation, tube insert and housing-Tube rating-Quality and intensity of x-rays, factors influencing them – measurement of kV,mA and time.

Unit 6: X-ray generator circuits: Vacuum tube diodes, Rectifiers, Semi conductor diode, diode as rectifier, half and full wave, selfrectification – X-ray generator; Electrical accessories for x-ray tubes, circuits and components,filament circuit- kilo voltage circuit-single phase generator-three phase generator - constantpotential generator. Fuses, switches and interlocks-Exposure switching and timers-HT cables -earthing.

Half value layers, determination of HVL. Energy absorbed from x-rays, x-ray scattering, x-ray transmission through the medium, linear and mass attenuation coefficient, HVT and TVT.

Unit 7 : Radioactivity: Discovery of radioactivity, natural radioactivity - activity units - Radioactive series, radium,thorium and uranium series- alpha, beta decay and gamma rays - radioactive disintegration-exponential decay, half life period, decay constant. Artificial radioactivity –production ofradioisotopes - nuclear reactor, cyclotron – neutron flux, fission and fusion-chain reaction-atombomb.

Unit 8 : Non-Ionizing Radiation Physics : Role of Non-ionizing radiation in Medicine, Bioacoustics, Ultrasound – Principles, Production,properties and uses in medical diagnostics and therapy. Radiofrequency and Microwave radiation,Infra red and Ultraviolet radiations, lasers and its applications in medicine.

Unit 9 :General concepts of measurements : Fundamental definitions – accuracy and precision, repeatability and reliability of measurements –Different kinds of errors – internal and external estimation of errors in laboratory experiments.



Reference books 1. First year Physics for Radiographers - Hay & Hughes. 2. Basic radiological physics-K.Thayalan, Jaypee publishers (P) Ltd, New Delhi(2001) 3. Fundamental of X-ray and Radium Physics - Joseph Selman 4. Basic Medical Radiation Physics - Stanton. 5. Chrtistensen's Physics of Diagnostic Radiology – Christensen.





Course Title : Hospital Practice, Patient Care & Medical Ethics






Course objective :

To impart the knowledge of Patient Care related to Hospital Practice specially to Radiotherapy patients and the Medical Ethics

Course Outcomes :

After completion of the course the students shall be able to understand:1. The Hospital procedures and care of the patients2. The principles of Infection, First Aid and asepsis.3. Medical Ethics required in the hospital and treatment procedures

SYLLABUS Unit 1 : Hospital procedure: Hospital staffing and organization; records relating to patients and departmental statistics; Radiotherapy Department staffing and organization; professional attitude of the technologist to patients and other members of the staff; medico- legal aspects; accidents in the departments/organization; minimizing waiting time; out-patient and follow-up clinics; stock-taking and stock keeping. Unit 2 : Care of the patient : First contact with patients in the department; management of wheel chair and stretcher patients andaids for this, management of the unconscious patient; elementary hygiene; personal cleanliness; hygiene in relation to patients (for example clean linen and receptacles, nursing care; temperature, pulse and respiration; essential care of the patient who has a tracheostomy; essential care of the patient who has a colostomy; bedpans and urinals; simple application of a sterile dressing. Unit 3 : First aid : Aims and objectives of first aid; wounds and bleeding, dressing and bandages; pressure and splints,supports etc. Shock; insensibility; asphyxia; convulsions; resuscitation, use of suction apparatus, drug reactions; prophylactic measures; administration of oxygen; electric shock; burns; scalds; hemorrhage; pressure points; compression band. Fractures; splints, bandaging; dressing, foreign bodies ; poisons.



Unit 4 : Infection : Bacteria, their nature and appearance ; spread of infections; auto-infection or cross-infection; the inflammatory process; local tissue reaction, general body reaction; ulceration; asepsis and antisepsis. Unit 5: Principles of asepsis:

Sterilization - methods of sterilization; use of central sterile supply department; care of identification of instruments, surgical dressings in common use, including filamented swabs, elementary operating theatre procedure; setting of trays and trolleys in the radiotherapy department

Unit 6 : Drugs in the department :

Storage : classification; labeling and checking, regulations regarding dangerous and other drugs; units of measurement, special drugs, anti-depressive, anti-hypertensive etc.

Medical Ethics:

Unit 1 : Introduction to Medical Ethics:

What is Ethics? What are the values & norms? Relationship between being ethical & human

fulfillment. How to form a value system in one’s personal & professional life? Heteronomous

Ethics & Autonomous Ethics. Freedom & personal Responsibility.

Unit : 2 : Definition of Medical Ethics:

Difference between medical ethics & bio-ethics Major Principles of Medical Ethics

Beneficence=fraternity, Justice=equality, Self determination(autonomy)=liberty

Unit 3 : Perspective of Medical Ethics:

The Hippocratic oath. The Declaration of Helsinki, The WHO Declaration of Geneva International

code of Medical Ethics(1993), MCI Code of Ethics(2002)

Unit 4 : Ethics of the individual:

The patient as a person, The Right to be respected, Truth & confidentiality, The autonomy of

decision, The concept of disease, health & healing, The Right to health, Ethics of Behaviour

modification, The Physician-Patient relationship, Organ donation

Unit 5 : The Ethics of Human life:

What is human life? Criteria for distinguishing the human & the non-human Reasons for respecting

human life, The beginning of human life Conception, contraception, Abortion, Prenatal sex-

determination, IVF,AIH, AID, SIFT, GIFT, ZIFT, genetic Engineering

Unit : 6 : The Family & Society in Medical Ethics:

The Ethics of human sexuality, FP perspectives, Prolongation of life, Advanced life directives-The

Living Will, Euthanasia, Cancer & Terminal Care



Unit : 7 : Death & Dying:

Use of life-support systems, Death awareness, The moment of death, Prolongation of life, Ordinary

& extraordinary life support, Advanced life directives, Euthanasia-passive & active, Suicide-the

ethical outlook, The right to die with dignity.

Unit :8 : Professional Ethics:

Code of conduct, Contract & confidentiality, Charging of fees, Fee-splitting, Prescription of drugs,

Over-investigating the patient, Low-Cost drugs, vitamins & tonics, Allocation of resources in

health care, Malpractice & Negligence.

Unit 9 : Research Ethics:

Animal & experimental research/humanness, Human experimentation, Human volunteer research-

Informed Consent, Drug trials.

Reference books1. Deeley – A guide to Radiotherapy nursing.2. Care of patient in diagnostic Radiography - Chesney & Chesney. 3. Chesney's Care of the patient in Diagnostic Radiography – Pauline J . Culmer. 4. Aid to Tray and Trolley Setting - Marjorie Hougton 5. First Aid - Haugher & Gardner 6. A guide to Oncology nursing (Livingstone) - Deeley 7. Practical nursing and first- aid - Ross and Wilson.8. Capra : Care of the cancer patient9. Sutton P M : Nature of cancer (London, English University press) 10. Sulton and Maurice : Cancer




BACHELOR OF RADIATION THERAPY TECHNOLOGY (BRTT) 2nd YEAR

Course Title : Physics of Radiotherapy & Imaging Techniques





Course assessment : Sessional test and/or home assignment 25%; Annual exam 75%

Course objective :

To impart the knowledge of Physics applications in Radiotherapy and Imaging

Course Outcomes :

After completion of the course the students shall be able to understand:1. The interactions of ionizing radiations with matter2. The dosimetry and dosimeters used in radiation measurements3. Physics of Imaging and Imaging concepts and film processing 4. Basic radiological physics required in radiotherapy

SYLLABUS

Unit 1 : Interaction of Radiation with matter Radiation transmission through matter, Interaction of electromagnetic radiation with matter –Thomson scattering (coherent scattering), Photoelectric and Compton effects – Pair production –relative importance - energy absorption – attenuation co-efficients. law of exponential attenuation,half value layer, linear attenuation coefficient-Interaction of particle radiation with matter –neutrons, heavy ions, nuclear reactions – range and Bragg curve. Interactions of x and gamma raysin the body; fat-soft tissue-bone- contrast media-total attenuation coefficient-relative clinicalimportance

Unit 2 : Radiation and radioactivity units and quantities :

Flux, Fluence, Exposure, Activity, photon fluence, intensity, absorbed dose, KERMA, LET, SIunits of radiation quantities.,

Radiation therapy – beam therapy – particle therapy, History & properties of Radium needles,tubes and its uses, Co-60 and Cs-137, Ir-192 seeds and wires.



Unit 3 : Basic Radiotherapy Physics

Historical developments in Radiotherapy, Physical components of Telecobalt Unit / Linear Accelerator Unit / Remote Afterloading Unit / Gamma Knife Unit / Simulator and their descriptions, Various types of sources used in Radiotherapy and their properties. Physics of Photons, electrons, protons and neutrons in radiotherapy, Build up and dose maximum, Physical parameters of dosimetry such as Percentage Depth Dose, Tissue-Air Ratio, Tissue Maximum Ratio, back scatter factor- Equivalent square field concept, Physics of Bolus and Phantom materials, Compensators, Wedges, Shielding Blocks, Patient immobilization devices. Useof PDD charts for isodose distribution- SSD and SAD technique - rotation technique--Time and dose calculations in SSD,SAD and rotation therapy. Worked examples for cobalt-60 and linac treatments. Electron beam therapy - interactions - energy specification – characteristics of electron beams.

Unit 4 : Physics of Imaging :

Basic principles of radiation imaging techniques. Absorption characteristics of body tissues.Computerised Tomography(CT) – History, CT Generations, geometric generation of tomography– Image reconstruction –basic principles. - Ultrsound imaging – Doppler effect, Piezo ElectricEffect, Scintillation detectors.- Basic principles of Magnetic Resonance Imaging(MRI) - Isotopeimaging techniques – Nuclear Medicine – Rectilinear Scanners and Gamma Cameras – PositronEmission Tomography (PET) & SPECT. Isotopes used in Radioisotope imaging techniques.Isotopes used in Nuclear Medicine, Biological and Effective Half Life, Absorbed dose arising fromRadionuclides within the body. Diagnostic and Therapeutic uses of colloidal Radioactive Isotopes.Digital Image processing – Grey scale, histogram, signal to noise ratio, digital filtering, Dataacquisition, display devices, data storage devices.

Unit 4 : Radiographic Film Processing :

The X-ray Dark Room, lightproofing, ventilation, radiation protection. Film markers, pass throughfilters. Developer, Fixer solution, their chemical composition, preparation and process ofdeveloping a film. The radiographic image, effect of exposure factors on contrast and imagequalities.

Unit 5 : Radiation detection and measurements: Principle of radiation detection - Ionisation of gases, fluorescence and phosphorescence, effect on photographic emulsion. Ionization chamber-proportional counter-GM counters - scintillation detectors - semiconductor detector-Gamma ray spectrometer. free air ionization chamber-thimble ion chamber-condenser chamber - Victoreen electrometer-secondary standard dosimeter – photographic film dosimeter - calorimeter - chemical dosimeter - Thermoluminescent dosimeter, Radiation survey meter-zone monitor-contamination monitor, their function use and maintenance. Advantages and disadvantages of various detectors, appropriateness of different types of detectorsfor different types of radiation measurement.

Reference books



12. The Physics of radiation therapy - Faiz M Khan, Williams and Wilkins(1994) 13. Johns.Harold and Cunningham : Physics of radiology (USA Charles C Thomas) 14. Massey and Meredith – Text book of physics applied to radiotherapy and radio

diagnosis. 15. Joseph Selman – Part II Physics of radiotherapy explained 16. Radiographic Imaging - Chesney & Chesney, Blakwell scientific publications,

oxford(1981) 17. Radiographic imaging-Derrick P.Roberts and Nigel L.Smith.Churchill Livingstone,

Edinburgh (1994) 18. Radiographic Latent image processing - W.E.J. Mckinney 19. Photographic processing, quality control and evaluation of photographic material -

J.E. Gray 20. Physical and photography principles of Medical Radiography -Seeman & Herman.21. Avinash C. Kak, Principles of Computerised Tomographic Imaging. IEEE PRESS22. The Physics of Medical Imaging, S. Webb, Institute of Physics Publishing, 1988.23. Christensen's Physics of Diagnostic Radiology by Thomas S. Iii Curry, James E. Dowdey,

Robert C., Jr Murry, Lea & Febiger Publishing, 4th edition, 1990.24. Introduction to Radiological Physics and Radiation Dosimetry, F. H. Attix, John Wiley and

Sons Publishing, 198625. The Modern Technology of Radiation Oncology, J. Van Dyk, Medical Physics Publishing,

1999.



Course Number and Title :RT-202 - BRTT 2ND (Basic Radiotherapy Equipments and Process, and their applications.)

Credits :Course Category : BSPre-requisite(s) :Contact Hours (L-T-D) : 3-2-1 (60 Hrs)Type of Course : Theory

Course Assessment: Internal Assessment (1 Hour) (25%) Annual Examination (3 Hour) (75%)

Course Objectives

To learn the fundamental concepts of Basic Radiotherapy Equipments and Process, and their applications.

Course OutcomesAfter completing this course the students should be able to:

1. The basic and applied knowledge of Teletherapy Machines including various Kilovoltage and Megavoltage Machines like betatron-microtron, Telecaesium units, Cobalt- 60 units and Linear accelerator.

2. The basic and applied knowledge of Brachytherapy Machine & Sources, Various Dose Rates, Pre and After Loading Techniques, Different types of applicators and templates, Brachytherapy methods-Mould-implant-Intracavitory-Intraluminal, Radiographic verification of implant-Orthogonal verification of intracavitary application-dose calculation methods.

3. The basic and applied knowledge of various Beam Directing and Modification devices like collimators, penumbra trimmers, Front and back pointer-pin and arc, Tissue compensators, Field blocks, Multileaf collimators, Wedges, Compensators, Bolus etc.

4. The basic and applied knowledge of various Immobilization and Positioning Devices.5. The basic and applied knowledge of various Simulators, Treatment verification, Correction

for contour irregularities, Corrections for tissue inhomogeneities etc.

Syllabus

Unit 1 : Teletherapy machines: Kilvoltage units-Grenz ray therapy-contact therapy-superficialtherapy-Deep therapy. Mega voltage therapy - Van de Graff generator - Linear accelerator -betatron-microtron. Radioisotope machines - History – Teleradium and Telecaesium units, Cobalt-



60 units –source housing – various shutter mechanisms, beam collimation and penumbra-Heavyparticle beams.Unit 2 : Treatment planning concepts: Isodose chart-Measurement of isodose curves-parametersof isodose curves. Wedge filters-Wedge field techniques-Combination of radiation fields-Isocentrictechniques-tumor dose specification. Simulator - treatment verification-Correction for contourirregularities-Corrections for tissue inhomogeneities. Treatment planning system-external beamplanning-brachytherapy planning.Unit 3 : Beam directing devices: Different types of collimators- penumbra trimmers-Front andback pointer-pin and arc. Tissue compensation-Field blocks-field shaping-multileaf collimator-IMRT concept-separation of adjacent fields.Unit 4 : Brachytherapy: Radioactive sources - calibration of brachytherapy sources- Afterloading systems - Manual pre loading systems - manual after loading systems - BARC Cs-137 kit-LDR remote after loading system and HDR remote after loading system - different types ofapplicators and templates, Brachytherapy methods-Mould-implant-Intracavitory-Intraluminal-Radiographic verification of implant-Orthogonal verification of intracavitory application-dosecalculation methods.Unit 5 : Radiotherapy simulatorsConventional simulators - CT simulators - cone beam CT simulators (CBCT) – comparison andquality assurance of simulators - different simulation techniques - Orthogonal, Semiorthogonal,Isocentric, Variable angle and Stereo-Shift.

Text Book(s)/Reference Book(s)

1. The Physics of radiation therapy-Faiz M Khan, Williams and wilkins(1994).2. Johns.Harold and Cunningham : Physics of radiology (USA Charles C Thomas).3. Massey and Meredith – Text book of physics applied to radiotherapy and radio diagnosis.4. Joseph Selman – Part II Physics of radiotherapy. Explained.5. Fletcher, Gilbert : Radiation therapy in the management of cancers.6. Barnes and Rees : Concise text book of radiotherapy.7. Walter and Miller : Short text book of radiotherapy.8. Moss: Radiation Oncology – Rationale, technique & results.

Course OutcomesProgram Outcomes (POs)

a b c d e f g h i j k1 x x x2 x x3 x x4 x x x5 x x x x



Course Title : Principles and Practice of Radiotherapy




Course objective and outcome :

SYLLABUS

Unit 1 : Introduction to Clinical Radiotherapy:Cell cycle/structure/function, Tissue structure/types/ features and functions/ Tissue importance in Radiation Therapy. Organs and systems (Structure/function) – Skin/ Central Nervous System/ Autonomic Nervous System / Peripheral Nervous System /Lymphatic System/ Endocrine System/ Urinary/ Respiratory System / Digestive System / Cardiovascular System, Bone and Muscle, Surface Anatomy/ Cross-sectional Anatomy – Brain & Cranial NSSurface Anatomy – Head & Neck/ Lower Limb (Pelvis)/ Chest/ Abdomen and LimbsOrgans and Systems – Skin/ Central Nervous System/ Autonomic Nervous System / PeripheralNervous System /Lymphatic System/ Endocrine System (Diseases encountered in the region)Multidisciplinary approach to cancer diagnosis and management and how the patient arrives in R.T. Treatment Intent : Curative,Palliative, Prophylaxis - Procedure in Radiotherapy department – Treatment Review, Importance of Follow-up – Instructions to Patients

Unit 2: Basic Pathology & staging of malignant tumor: Basic pathology-Carcinoma,Sarcoma-Lympoma,Pattern of Spread, Biopsy/Investigations relatedto malignant tumor-staging work up and TNM.Introduction of different malignant tumor treated inradiotherapy department including TNM. Skin-lip-oral cavity & Para nasal sinus-nasopharynx-orophaynx-hypopharynx-larynx-thyroid-postcricoid—oesophagus-mediastinum- lungs-pancreas-liver-breast- cervix-body of the uterus-vagina-valva-kidney,ureter,bladder,rectum-prostate,penis,testis-lymporeticulam, tissue-bonemarrow - CNS, eye, orbit-soft tissue & bone-pediatric tumor, retinoblastoma, wilm’s tumor,rhobdomyosarcoma

Unit 3 : Care of Cancer PatientsGeneral welfare of the patient during and after the treatment including the care any intercurrentdisease (diabetic, tuberculosis, arthritis). Diet and fluid intake. The observation and reporting anychange in the signs and symptoms of patients receiving treatment. The use of blood count in thecontrol of certain treatment. The care of local and systemic reaction. Local reaction should includethose in the ear, nose, throat and eye and those arising from treatments given to the pelvis. Care ofcancer patients. (Mucositis, Dermatitis, Cystitis, proctitis)

Reference books5. Walter and Miller: Short text book of radiotherapy 6. Meredith W J ( et al) Radiation dosage the Manchester system 7. Smith : Ivan H (et al) Cobalt 60 teletherapy



8. Silver and Solomon : Radioactive isotopes in Med. & Biol. 9. Wachsmann : Felise and Berth Gunther Moving field radiation therapy. 10. Murphy and Walter : Radiation Therapy 11. Sulton and Maurice : Cancer explained 12. Fletcher, Gilbert : Radiation therapy in the management of cancers 13. Moss William : Therapeutic radiology





Course Title : Radiobiology & Radiation Protection






Course objective :

To impart the knowledge of Radiation Biology and Principles of Radiation Protection

Course Outcomes :

After completion of the course the students shall be able to understand:1. The Biological Effects of Ionising radiation 2. The Principles of Fractionation in Radiotherapy3. The principles of Radiation Protection including the Hazards, Evaluation and Control

Measures4. Room Design planning of the Radiation installatiions5. The principles of Protection and monitoring devices 6. The code of practice and Role of monitoring agencies

SYLLABUS

Unit 1 : Biological effects of radiationPhysical Basis of Radiobiology, The Cell, Cell Cycle, cell divisions, Mode of action of ionizingradiation, effect of ionizing radiation on cell, chromosomal aberration, Radiation induced injuriesat cellular level, cell survival after irradiation, Acute Radiation syndrome, Radiobiology of HighLET Radiation, Oxygen effect, RBE, Effect of Ionizing Radiation on different organs & systems ofthe body. Fractionation. Somatic effects and hereditary effects, stochastic and deterministiceffects, Acute exposure and chronic exposure.Unit 2 : Radiation ProtectionPhilosophy of Radiation Protection, Effect of time, Distance and shielding, Calculation of workload, Calculation of weekly dose to the radiation worker and general public, good work practices in diagnostic radiology and radiotherapy practices. Equivalent Dose, Weighting Factors, Effective Dose, Natural Background Radiation, Occupational Exposure limits, Dose limits for public.



Unit 3 : Planning of radiation installationProtection from primary, leakage and scattered radiation. Planning consideration for radiology and radiotherapy installation including workload, use factor & occupancy factor, effect of different shielding material. Barrier design-barrier materials-concrete, brick& lead. Primary & secondary barrier design calculations. Design of doors. Control of radiation-effects of time, distance and shielding.

Unit 4 : Personnel monitoring systems principle and objective- Pocket dosimeters, Film Badges, TLD badges and their use in personnel monitoring. Area monitoring and radiation survey, practical use of survey meter, zone monitors and phantoms. Survey in teletherapy, brachytherapy and simulator units. Advantages and disadvantages of various PM badges. Personnel Monitoring Service.

Unit 5 : Radiation emergenciesEmergency preparedness, safety and prevention. Radiation Emergency Procedures : Safety and security of radiation sources, case histories of emergency situations and preparedness, equipments and tools including role of Gamma Zone monitor & Survey meters. Regulatory requirements and prevention of emergency, Preventive maintenance and Safety Culture, Role of Technicians in handling radiation emergencies.

Unit 6 : Safety code and work PracticesBuilt in safety specification for teletherapy and brachytherapy units-treatment room and control room safety-operational safety-radiation protection program-personnel requirements and responsibilities-regulatory controls Regulatory requirements : National regulatory body, responsibilities, organization, safety standards, codes and guides, responsibilities of licenses, registrants and employers and enforcement of regulatory requirements.

Demonstration :Time, Distance and shielding, measurement of HVT & TVT. Familiarisation of radiation survey meters and their functional performance checks, Radiological Protection Survey of Radiotherapy, Simulator and CT Simulator installations, QA on X-ray, Simulator and Radiotherapy Equipments, Procedures followed for calibration of measuring and monitoring instruments.

Reference books 9. Radiobiology for the Radiologist, Eric J. Hall, Lippincott Williams & Wilkins, 5th edition,

200010. Radiation Protection in Hospitals. Richard F.Mould 11. Basic radiological physics: K.Thayalan Jaypee brothers pvt ltd, New Delhi 12. An Introduction to Radiation Protection. Allen Martin & Samuel 13. Radiation safety in Medical practice. M.M. Rehani. 14. Radiation Protection. Ronald L. Kathren 15. AERB safety code, Mumbai





Course Title : Practicals and Viva-voce - 1

Course Code : RT-2P1


Contact Hours (P:D) : 2 : 1

Type of Course : Practical

Course assessment : Cinical Posting and/or home assignment 25%; Annual exam 75%

Course objective :

To impart the Practical knowledge of Dosimetry and Quality Assurance in Radiotherapy

Course Outcomes :

After completion of the course the students shall be able to understand and perform1. Quality Assurance tests of Radiotherapy equipments2. Radiation Protection Survey of Radiation Installations3. Dosimetric tests of Radiotherapy equipments

SYLLABUS

1. To find out the Timer / Shutter error of cobalt teletherapy unit

2. To Find the Field Size Factors for Theratron-780C cobalt teletherapy unit

3. To find the Tray factor of the Perspex shielding tray using cobalt teletherapy unit

4. Radiation Survey of the Teletherapy installation

5. Radiation Survey of the Brachytherapy installation

6. Congruence between Light and Radiation field for Th-780C cobalt teletherapy unit.

7. To prove Inverse Square Law.

8. To verify Area/Perimeter method

9. To find the HVL / attenuation factors




BACHELOR OF RADIATION THERAPY TECHNOLOGY (BRTT) 3rd YEAR

Course Title : Advanced Radiotherapy Equipments & Process






Course objective :

To impart the knowledge about advanced and latest radiotherapy equipments and processes

Course Outcomes :

After completion of the course the students shall be able to understand:10. Linear accelerators11. Conformal Radiotherapy with Multileaf collimator12. Stereotactic Radiosurgery and Stereotactic Radiotherapy13. Intensity Modulated Radiotherapy14. Image-guided Radiation Therapy

Syllabus

U nit 1 : Linear accelerators - Components of modern linear accelerator-Standing and travelling wave guides,Magnetrons and Klystrons. Bending Magnet, Target, Flattening filter, Collimators. Needfor high quality portal imaging- Fluoroscopic, diode, crystal , Ionization. chamberdetectors and film detectors,-" amorphous silicon- Diagnostic imaging on a linearaccelerator- Telecobalt Vs Linacs

Unit 2 : Conformal Radiot herapy With Multi Leaf Collimato r Introduct ion to CRT with MLC-Modern developments in MLC - Different categoriesof MLC commerciall y available MLC systems - Universal wedge - EnhancedDynamic wedge for Linac- cl i n ical application.

Unit 3 : Stereotactic Radio Surgery And Radiotherapy Introduction to SRS and SRT - SRS with Co-60 sources; the Gamma knife -sterevtactic multiple - arc radiotherapy with a Linac - Cyber knife -Dynamic SRS -Dynamic collimation for SRS with multiple arc- Intra operative radiation therapy



Unit 4 : Intensit y Modulated Radiotherapy Introduction to IMRT -Target and critical structure definitions for IMRT - Static MLCIMRT, Dynamic MLC IMRT, compensator based IMRT - comparison of IMRTdelivery systems, Introduction to serial Tomotherapy and Helical Tomotherapy. VMAT.Arc Therapy

Unit 5 : Image Guided Radiation TherapyConcept of IGRT, uses of imaging modalities, intrafraction and interfractionvariations, dedicated imaging systems for radiotherapy, in- room CT scanners, MVand KV imaging, respiratory gating: methods to manage respiratory motion inradiation treatment – X-ray imaging techniques for guidance in radiation therapysettings- clinical procedures in employing X-ray imaging technologies- effect ofmotion on the total dose distribution- basics of 4D computed tomography imagingand treatment planning

Reference Books11. Linear Accelerators for Radiation Therapy (Peter C. Williams)12. Radiotherapy: Principles to Practice (Griffith)/Basics of Radiotherapy, Technical Aspects

of techniques13. The Physics of radiation therapy-Faiz M Khan, Williams and wilkins(l994)14. Johns.Harold and Cunningham : Physics of radiology (USA Charles C Thomas)15. Massey and Meredith - Text book of physics applied to radiotherapy and radio diagnosis



Course Title : Clinical Radiotherapy




Course objective and outcome :

SYLLABUS

Unit -1 : Principles of Radiotherapy & ChemotherapyTumours from different organs and organ systems. Basic Principles of Radiotherapy and differentRadiotherapeutic technique. Basic Principles, Classification, mechanism of action, Indication &toxicity of Cancer Chemotherapy.

Unit -2 : Patient Treatment setup Mould Room activities, Errors – Immobilization / Positioning Procedures, Positioning Aids – Benefits / Limitations, Care of Patient – Lifting and Moving Techniques for patient and staff safety, Benefits / Limitations of Thermoplastic Mask, Hip and pelvis positioning and immobilization, Breast and Thorax Positioning, Limitations of Breast and Thorax Positioning.

Beam Shielding blocks, preparation, HVL requirements, materials used, Critical organs, doselimits for organs, Styrofoam cutting, shadow trays, Electron filters.Bolus requirements, tissue compensating bolus, bolus materials, Unit – 3: Principles of Professional PracticeProfessional Aspects –, Appearance and Hygiene, Universal Precautions – History and role of radiotherapy in cancer, Human body with typical technical terminology, General Care of the patient, Setup reproducibility, Basic Nursing Procedures for patient care and emergency situations

Procedure in Radiotherapy department – First Visit to include Room Preparation, Equipment andDocumentation and assistance with procedures / examinations, Professional development skillsTreatment preparation, Treatment equipment, Treatment set-up and delivery, Patient care, Care of the Cancer Patient.

Unit – 4 : NutritionNutrition – It’s health aspect and importance in Oncology, Health education, Psychosocial aspect of Oncology, Knowledge of Occupational disease & health aspects of Industries & other Occupations.

Unit – 5 : Environment Science And HealthIntroduction to Environment and Health Sources, health hazards and control of environmental pol-lution, Water, The concept of safe and wholesome water. The requirements of sanitary sources of water. Understanding the methods of purification of water on small scale and large scale. Various biological standards, including WHO guidelines for third world countries. Concept and methods



for assessing quality of water. Domestic refuse, sullage, human excreta and sewage their effects onenvironment and health, methods and issues related to their disposal.

Reference books1. Walter and Miller: Short text book of radiotherapy 2. Meredith W J ( et al) Radiation dosage the Manchester system 3. Smith : Ivan H (et al) Cobalt 60 teletherapy.4. Text Book of Environmental Studies for under gradute courses By Erach Bharucha Reprin-ted in 2006, Orient Longman Private Limited /Universities Press India Pvt. Ltd.5. Silver and Solomon : Radioactive isotopes in Med. & Biol. 6. Wachsmann : Felise and Berth Gunther Moving field radiation therapy. 7. Murphy and Walter : Radiation Therapy 8. Sulton and Maurice : Cancer explained 9. Fletcher, Gilbert : Radiation therapy in the management of cancers 10. Mos William : Therapeutic radiology





Course Title : Biostatistics, Computer Skills & Patient Data Maintenance






Course objective :

To impart the knowledge of applications of Statistical techniqiues, Computers and Patient Data Maintenance relevant to Radiotherapy

Course Outcomes :

After completion of the course the students shall be able to understand:1. The basic statistical techniques applied to medicine and biology2. The applications of Computers including the hardware and softwares3. The softwares useful in data maintenance and radiotherapy 4. The Paper based and Electronic Patient Data maintenance

SYLLABUS

Biostatistics:Unit - 1 : Introduction to BiostatisticsIntroduction and scope of biostatistics, use of statistics in biology. Population and sample. Stages of research, types of data and methods of data collection.

Unit – 2 : Tabulation of DataData arrangement and presentation, formation of tables and charts. Raw data, the array, frequency distribution. Basic principles of graphical representation. Types of diagrams - histograms, fre-quency polygons, smooth frequency polygon,commulative frequency curve, Normal probability curve.

Unit - 3 : Measure of Central TendencyNeed for measures of central tendency, Definition and calculaton of mean - ungrouped and grouped Meaning, interpretation and calculation of median ungrouped and grouped. Meaning and calculation of mode. Comparison of the mean, and mode. Guidelines for the use of various meas-



ures of central tendency.

Unit - 4 : Measure of VariabilityNeed for measure of dispression.The range, the average deviation.The variance and standard devi-ation. Calculation of variance and standard deviation ungrouped and grouped. Properties and uses of variance

Unit -5 : Probability and Standard Distributions.Probability rules. Binomial, poisson and normal distributions. Hypothesis testing: Student ‘t’ test, Chi square test, Analysis of variance. Correlation and regression. Experimental designing, planning of an experiment, replication and randomization.

Computer Skills :Unit -1 : Introduction to computersIntroduction to computer – I/O devices – memories – RAM and ROM – kilobytes. MB, GB their conversions –Operating systems– DOS, Windows, Linux and Unix- Number system – Binary and decimal conversions –– Networking – LAN, WAN.

Unit -2 : WordprocessingTyping text in MS word – Manipulating text – Formatting the text – using different font sizes, bold, italics – Bullets and numbering – Pictures, file insertion – Aligning the text and justify – choosing paper size – adjusting margins – Header and footer, inserting page No’s in a document – Printing a file with options – Using spell check and grammar – Find and replace – Mail merge – inserting tables in a document.

Unit -3 : SpreadsheetsCreating table in MS-Excel – Cell editing – Using formulas and functions – Manipulating data with excel – Using sort function to sort numbers and alphabets – Drawing graphs and charts using data in excel – Auto formatting – Inserting data from other worksheets.

Unit -4 : Slide/Powerpoint presentationsPreparing new slides using MS-POWERPOINT – Inserting slides – slide transition and animation – Using templates – Different text and font sizes – slides with sounds – Inserting clip arts, pictures, tables and graphs – Presentation using wizards.

Unit – 5 : Internet and its usesIntroduction to Internet – Using search engine – Google search – Using Web Browsers – Uploading and Download of files and images – E-mail ID creation – Sending messages – Attaching files in E-mail – Introduction to Software languages – Components of Software languages - Different variables, declaration, usage – Constants – Sub programs – Interpreter & compiler.

Patient Data ManagementUnit - 1 : Medical RecordsRevision : Definition and history of medical record-Values, purposes and uses of medical record-Contents and components of medical record-Responsibilities of Radiotherapy technicians, hospitaladministrators, Doctors, nurses and allied health professionals in relation to medical records.



Unit – 2 : Management of medical recordsNumbering, filing, storing and retrieving medical records-Maintenance of Registers- admission, discharge, MLC registers – Daily treatment/simulation/mouldroom Registers, Radiotherapy registration - Analysis of medical records - Medico legal aspects, Medical confidentiality-Consents– Types of consent (Informed, implied, express, etc.)

Unit – 3 : Use of computers for data managementIntroduction to the design, maintenance and use of data management systems for the collection andanalysis of research data, especially epidemiologic research data on humans. MS Access, MS Excel and other data management & Statistical packages are emphasized. Topics include: database development, data manipulation and cleaning, data summarization, and selected topics in statisticalanalysis programming.

Demonstration/PracticalsIndentification of various parts of the PC, Demonstration of dis-assembly and assembly of PC and interconnection of Input and Output devices to PC, Familiarization with start menu, taskbar icons, windows explorer, Control panel of settingsMS-Word, Basics of Letter writing,tempalates, wizards, formatting documentsCreating Graphics, tables, etc. using MS-Word, Building a sample worksheet using MS-ExcelFormulas for calculations, sorting etc..

Reference BooksB.K. Mahajan & M. Gupta (1995) Text Book of Preventive & Social Medicine, 2002,17th Edition Jaypee Brothers.





Course Title : Practicals and Viva-voce - 1I

Course Code : RT-3P1


Contact Hours (P:D) : 2 : 1

Type of Course : Practical

Course assessment : Clinical Posting 25%; Annual exam 75%

Course objective :

To impart the Practical knowledge of Radiotherapy procedures, Patient Setup

Course Outcomes :

After completion of the course the students shall be able to understand and perform11. Radiotherapy procedures 12. Mould Room Procedures13. Simulation Procedures14. Simple Teletherapy Planning Calculations

SYLLABUS

1. Mould Room 1 : Thermoplastic Immobilisation cast preparation

2. Mould Room 2 : Build up bolus preparation

3. Mould Room 3 : Custom shielding block preparation

4. Teletherapy Simulation of patient using x-ray machine

5. Brachytherapy Simulation for ICRT patients

6. Teletherapy Planning : simple planning calculations

7. Brachytherapy Planning : simple planning calculations



8. Treatment Delivery : Teletherapy – simple parallel opposing fields

9. Treatment Delivery : Teletherapy – multiple fields (more than 2) setup

10. Treatment Delivery : Brachytherapy


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