determining properties of wound dressings for negative pressure wound therapy
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Determining Properties of Wound Dressings for Negative Pressure Wound Therapy. Lora Aboulmouna, Lisa Lewicki, Ryan Frye. What is NPWT?. - PowerPoint PPT PresentationTRANSCRIPT
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Determining Properties of Wound Dressings for Negative
Pressure Wound Therapy
Lora Aboulmouna, Lisa Lewicki, Ryan Frye
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What is NPWT?The application of sub-atmospheric pressure to a sealed wound for the purpose of removing fluid and stimulating a cellular response through the mechanical stretching of wound tissue.
Process: Material inserted into wound bed Sealant drape Fluid drain tube Vacuum Applied
-50 to -120 mmHg
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Pioneer Technology
Aims to discover and create solutions in the healthcare community beginning with advancements in wound care while bridging the gap between healthcare technology and nature Green healthcare Discover the benefits of Sorbact and likelihood of
commercial success
Mentor: Josh Smith, Vice President of Pioneer Technology
Advisor: Dr. Jack Fisher, Associate Clinical Professor of Plastic Surgery at Vanderbilt University
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Wound Dressings
Sorbact
Gauze
KCI Foam
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Project Goals
To determine
Material resistance Flow rate Pressure gradient Saturation points
of the three materials in a negative pressure environment.
Build a model that provides a controlled environment
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Equating the Materials
Procedure: Obtained three materials with equal masses Measured water displacement in a graduated
cylinder of each sample Mass and volume were used to determine the
density of each material
Material Density (g/ml)Gauze 1.48
KCI Foam 0.62Sorbact 1.36
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Preliminary Experiment: Material Behavior in NP Environment Used skin analog in
mold to simulate wound bed
Inserted appropriate material amount
Covered with sealant drape
Applied pressure of 180 mmHg Observed material
compression
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Results of Preliminary Experiment
All materials compressed under negative pressure
Sorbact Gauze KCICompression (mm)
16 19 13
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Design Setup
Clinical Pressure Ranges:
-50 to -120 mm Hg
Bernoulli’s Principle: Height of water Fluid velocity Vacuum
Pressure Density Head losses
Pipe
h
Q
P = -180 mm Hg
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Design Obstacles
Resistance of tubing Flow meter range accuracy (o.4 to 40
mL/min) Small flow rates may cause readings to not
be significantly different All flow travels through materials Varying Pressure
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Future Directions
Obtain accurate flow measurements Awaiting shipment of proper flow meter
Test flow while varying pressure Test saturation
Weigh materials before and after saturation
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References Borgquist O, Ingemansson R, Malmsjö M. Wound edge
microvascular blood flow during negative pressure wound therapy: examining the effects of pressures from -10 to -175 mmHg. Plast Reconstr Surg In press.
Ljungh, A, N Yanagisawa, and T Wadström. "Using the principle of hydrophobic interaction to bind and remove wound bacteria." Journal of Wound Care 15.4 (2006): n. pag. Web. 6 Nov 2010.
Smith, Jan, and Peter Robertsson. Method for Dressing a Wound. , 2010. Web. 27 Oct 2010. <http://www.google.com/patents/about?id=ApHVAAAAEBAJ&dq=sorbact>
"Science Behind the Therapy — KCI." Science Behind The Therapy. Web. <http://www.kci1.com/KCI1/sciencebehindthetherapy>.