DetoxificationAnd Cleansing 

Marianne Marchese N.D.Naturopathic Doctor

7331 E Osborn Rd ste 330Scottsdale AZ 85251

480-990-1111www.drmarchese.com

Introduction

• What is detoxification and cleansing?

• Why do we need detoxification?

• Who should detoxify?

• How do we detoxify?

• What does a detoxification treatment plan look like?

Detoxification and cleansing

•Detoxification involves either clearing toxins from the body or neutralizing or transforming them.

Health and vitalityClear symptomsTreat diseasePrevent future problems

Toxins

• A toxin is any substance that creates an irritating and/or harmful effect in the body.

• Water, food, air, cosmetics, products

• Exposure to chemicals, pesticides, solvents, heavy metals, and molds.

Why do we need detoxification?

• Low dose daily exposure builds up in our bodies over time.

• Air

• Water

• Food

• Products

• Hobbies/lifestyle

Indoor air pollutants

1. Dust mites, molds, pet dander, and microbes 2. Asbestos, lead, radon 3. Synthetic consumer products-solvents 4. Second hand smoke 5. Formaldehyde (foam insulation, wood and carpet

glue, paint preservatives) 6. Pesticides

Water

• Types of water pollutants include:• Soil run-off• Solvents• Pesticides/herbicides• Heavy metals• Nitrates from sewage and fertilizers• Hormones• Chloroform

Food sourcesFish

• Mercury can act as a neurotoxin to the developing fetus and adults

• Mercury concentrations in the blood as a result of fish consumption is linked to infertility in men and women.

Fish high in mercuryWild fish

• Swordfish

• Shark

• King mackerel

• Fresh tuna

• Sea bass

• Canned white tuna(albacore)

Fish high in PCB’s and DioxinFarmed fish

• Fatty fish concentrate PCB’s and Dioxin which may impair memory and learning in adults.

• Although fatty fish are a good source of omega-3 fatty acids so are tofu, soy, canola oils, walnuts, and flax seeds.

Fish low in mercury and fat

• Salmon

• Blue crab

• Haddock

• Pollack

• Flounder

• Trout

Food sourcespesticides

• Pesticides found on foods sitting in the store ready for consumption, may affect the developing nervous system, cause cancer, and interfere with endocrine activity.

Most contaminated foods

• Apples Bell peppers• Celery Cherries(U.S.)• Imported grapes Nectarines• Peaches Pears• Potatoes Spinach• Red raspberries Strawberries

Products at Home

• Cleaning supplies

• Cosmetics and grooming products

• Plastics

• Detergents and soaps

• Carpet

• Pergo

Other sources of toxic compounds

1. Pesticides and herbicides

2. Detergents and household products

3. Plastics (food wraps, soda, baby and water bottles)

4. Industrial and auto exhaust

5. Dental restorations

6. Animal products, hormone injected animals

7. Cosmetics and grooming products

Examples of disrupting compounds

• Dioxins

• Polychlorinated biphenyls (PCB’s)

• Bisphenol-A

• Organochlorine pesticides (DDT)

• Phthalates

• Heavy metals (lead, mercury, cadmium)

Dioxins

• Produced by incineration and combustion• Produced by manufacture of chlorine containing

products such as pesticides and wood preservatives and the bleaching of paper

• Accumulates in human fat tissue and animals high on food chain

• Decreases T4 and T3, and testosterone. Both estrogenic and anti-estrogenic

PCB’s

• Used as coolants, lubricants, insulation for electrical equip, in paints, plastics, dyes and rubber. Made wood and plastics non-flammable

• Accumulates in human fat, food chain and found in rivers and lakes

• Same effects as dioxin plus low birth weight, delayed neuro development, low IQ, weakened immune system and some behave like estrogen

Bisphenol-A

• A compound found in polycarbonate plastics. Used in manufacture of compact disks, plastic bottles, lining of metal food cans, and dental sealants

• Estrogenic influences-binds to ER+ breast cancer cells.

• Decreases sperm count, increases prostate size.

DDT and metabolites

• An insecticide for agricultural use and mosquitoes

• Estrogenic effects-induce cell proliferation in ER+ breast cancer cells, shortened period of lactation, and pre-term births

• DDE(metabolite) is an androgen antagonist and leads to feminization of the male fetus

Phthalates

• Additive to PVC plastics to make them soft, flexible and strong. (toys)

• Carpet backing, paints, glues, insect repellents, hair spray, and nail polish

• Anti-androgenic-prenatal exposure causes hypospadias, undescended testicles

• Suppressed ovulation, estradiol production, and PCOS(rat studies)

Don’t forget

• 1. Solvents

• 2. Parabens

• 3. Formaldehyde

• 4. Names you can’t pronounce-in cleaning supplies, soaps, detergents, lotions, shampoos, cosmetics.

Who needs detoxification?

Asthma/allergies Skin Rash

Anxiety Fatigue

Depression Prostate

Cancer Thyroid

Immune conditions Fertility

Endometriosis Fibroids

Signs and symptoms con’t

Constipation Loose stool

Bad breath Indigestion

Allergies Headaches

Menstrual problems Fatigue

Fibrocystic breasts Neuropathy

Environmental sensitivity

How do we detoxify/cleanse?

• Determine toxic load

• Exposure and health history

• Support our detox organ systems-Functionally, poor digestion, colon dysfunction, decreased liver function and poor elimination all increase toxicity.

• Follow an individualized detoxification plan

Testing for toxic load

• 1. Exposure history

• 2. Heavy metal hair analysis

• 3. Heavy metal urine analysis

• 4. Solvent and pesticide testing

• 5. Liver function testing

Detoxification systems

• 1. Gastrointestinal-liver, gallbladder, and colon• 2. Urinary-kidneys, bladder, and urethra• 3. Respiratory-lungs, throat, sinuses, mouth/nose• 4. Lymphatic-lymph channels and nodes• 5. Skin-sweat and sebaceous glands

• Prior to beginning a detoxification program it is essential that every detox system is functioning properly.

Liver

• The liver excretes hormones such as estrogen, cortisol, aldosterone, and thyroxin.

• The liver detoxifies these and other hormones and excretes them into the bile.

• If the liver malfunctions, toxins and hormones accumulate in the body causing disease.

Intestinal health

• Prolonged toxic irritation to the lining of the GI tract

• Nutritional insufficiencies• Exposure to bacterial endotoxins• All result in unfavorable changes in the

permeability functions of the gastric mucosal lining.

 

Repair the GI tractThe 5R plan

• 1. Rebalance-diet, nutrition, and lifestyle• 2. Remove-any offending pathogen or food antigen

such as Giardia, Candida, H. Pylori, and food allergies• 3. Replace-HCL, digestive enzymes, and fiber• 4. Reinoculate-probiotics and

fructooligosaccharides• 5. Repair-nutritional support including L-glutamine,

pantothenic acid, zinc, anti-oxidants, bioflavinoids, essential fatty acids, and herbs such as aloe, DGL, and comfrey

Elimination

• 1. Kidneys help excrete toxins and breakdown products through the urine.

• 2. The colon eliminates toxins through the bile• 3. The skin and lymph system, through sweating

and circulating toxins to the organs of elimination, assist in detoxification as well.

• 4. It is important all organs of detoxification are functioning properly prior to a detox and are included in the overall detox plan.

. Detoxification Plan Overview

• Avoidance• Diet and Nutrition• Exercise• Hydrotherapy• Bowel support• Supplements• All parts of the plan must be incorporated for

optimal detoxification

Avoidance

• Take off your shoes when you enter the house• Non-toxic cleaning products, detergents, soaps,

grooming products• Don’t use insecticides, herbicides, pesticides in the

home or on the lawn• Use nontoxic dry cleaning or air it out before

bringing it into the home• Remove off-gassing sources-new furniture,

carpeting, upholstery• No new carpeting, paint, pressboard furniture ect.

Diet and Nutrition • 1.      Drink one half your body weight in ounces of filtered

water each day.• 2.      Eat organic only foods.• 3.      Avoids foods high in pesticides and mercury.• 4.      Avoid food allergies/sensitivities.• 5.      Include fruits, vegetables, whole grains, legumes,

nuts, and seeds.• 6.      Avoid red meats, organ meats, refined foods, canned

foods, sugar, saturated fats, hydrogenated oils, coffee, alcohol, and nicotine.

• 7.      Eat a natural seasonal cuisine.

Seasonal suggestions• Winter• Broccoli, cabbage, potato, kale, spinach, chard,

butternut squash, onion, cauliflower, collard greens, Jerusalem artichoke.

• Spring• Asparagus, baby carrots, spring garlic, red chard,

beets, leeks, broccoli, wild greens such as mustard, sorrel, or collard.

Seasonal con’t

• Summer• Zucchini, new potatoes, green beans, carrots,

onion, beets greens, yellow squash, bell pepper, eggplant.

• Autumn• Broccoli, cabbage, potato, celery, spinach,

cauliflower, onion, carrots, chard, sugar peas.

Foods that enhance liver metabolism  

• Cruciferous family vegetables-

• broccoli, brussel sprouts, cauliflower, kale, cabbage

• Beets, dark green leafy veggies

Diet examples

• Morning• Two glasses of filtered water with fresh squeezed

lemon• One piece of fruit such as an apple, pear, banana • One bowl of cooked grain such as millet, brown

rice, amaranth, quinoa, oats, or buckwheat• Healthy nut butter for sweetness• Green tea• Alternative-Detox smoothie

Diet con’t

• Afternoon/dinner

• 1-2 servings of steamed vegetables-see list from above

• Nuts, seeds, legumes (beans)

• One serving of protein

• Water or herbal throughout the day

Exercise/ Bowel support

• 30 minutes a day to get blood and lymph moving and increase perspiration

• Yoga and breathing exercises

• Massage/body

• Psyllium husk powder-2 tsp a day

• Ground flax seeds-2 Tbsp a day

Hydrotherapy

• Epsom salt baths for 10 minutes a day, end with cold rinse

• Alternating hot/cold shower

• Constitutional hydrotherapy

• Sauna (caution) low temp only

• Colonics

SupplementsThese can interact with drugs and herbs and can have side effects

1. Whey protein powder-increases glutathione levels2. N-acetlycysteine-Increases glutathione levels3. Selenium-Increases glutathione levels and an anti-

oxidant4. Vit-E-Required for Cyt P450 reactions and an anti-

oxidant, scavenges free radicals5. Calcium D-glucarate-Increases the net elimination of

toxic phase II conjugate.6. Muti-vitamin and mineral (if not doing formulated detox

powder in a smoothie)

Amino acidsThese can interact with drugs and herbs and can have side effects

a. L-methionine-It is a source of sulfur groups essential to phase II sulfation.

b. Glycine-It is a cofactor in phase I and II pathways

c. Glutamine-Heals the intestinal mucosa and protects it from toxic effects during detox.

d. Taurine-It is a cofactor for phase II reactions.

Liver HerbsThese can interact with drugs and herbs and can have side effects

1. Milk Thistle-Liver protective and an anti-oxidant. It blocks toxin-binding sites

2. Dandelion root-Liver and blood cleanser, diuretic, and filters toxins

3. Licorice-The great detoxifier.4. Burdock root-Improves liver function, antibacterial, skin

and blood cleanser5. Fringe tree-supports liver detoxification. The root is

hepatoprotective6. Greater celandine-Increases bile flow through the liver

Web Sites

• ORCOUNCIL.ORG• NOTTOOPRETTY.ORG• NOHARM.ORG• HEALTHYTOMORROW.ORG• THEGREENGUIDE.COM• EWG.ORG• PESTICIDE.ORG• DRMARCHESE.COM

Books

• Rachel Carson-Silent Spring

• Theo Colburn- Our Stolen Future

• Sandra Steingraber- Living downstream and Having Faith

• Ruth Winters- Consumer’s Dictionary of Cosmetic Ingredients

• Kim Erickson- Drop Dead Gorgeous