diabliss - world's first diabetic friendly cane sugar

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DIABLISS – WORLD’S FIRST DIABETIC FRIENDLY CANE SUGAR: INTRODUCTION & PRODUCT PERFORMANCE

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For the first time in the world we are able to render pure cane diabetic friendly sugar by blending sugar with a proprietary blend of herbal extracts using techniques from Ancient Classical Indian Medicine System. The herbal extract is derived from several herbs and spices (black pepper, turmeric, fenugreek, ginger, pomegranate, gooseberry and cinnamon) using water and no other chemicals or solvents. The herbal extract is colorless, odorless and tasteless and thereby restores the original taste factor of cane sugar & derivative products. Also, by blending the herbal solution with carbohydrates and fruit pulp, we are able to provide an integrated line of foods for carbohydrate and fructose management the first time in the world. These products enable diabetics to consume an unlimited choice of foods without compromising on taste factors and thereby restore serious lifestyle constraints that diabetics face every day with limited food choices. DiaBliss Sugar is coming to the world after 10 years of extensive research and development, with four years of testing among hundreds of diabetics. DiaBliss Sugar has been tested by world class accredited laboratories. The product has been tested in hundreds of people for periods ranging from 3 to 36 months and data to date indicates that the product is safe and in fact lowering long term blood sugar levels as measured by HbA1c. The product has been tested in subjects ranging in age from 7 to 82 and is effective in Type 1 & Type 2 diabetics. DiaBliss products have been launchedin Chennai, India in April 2013. This will now be followed by larger scale launch in India and outside India. With diabetes reaching epidemic levels all over the world, especially in India, China and Middle East, we are hoping DiaBliss can contribute its part in making living happier and healthier for diabetics and pre-diabetics. DiaBliss products can be used by the entire family for health and general wellbeing.

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Page 1: Diabliss - World's First Diabetic Friendly Cane Sugar

DIABLISS – WORLD’S FIRST

DIABETIC FRIENDLY CANE SUGAR:

INTRODUCTION & PRODUCT

PERFORMANCE

Page 2: Diabliss - World's First Diabetic Friendly Cane Sugar

Diabetes Mellitus

Diabetes (diabetes mellitus) is classified as a

metabolism disorder

Types of diabetes – Type 1, Type 2 & Gestational

Diabetes (i.e. during pregnancy). 80% of diabetic

population is type 2.

In diabetics the body either does not produce

enough insulin, produces no insulin (Type 1), or has

cells that do not respond properly to the insulin the

pancreas produces (type 2).

Diabetes effects almost every organ in the body

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Page 3: Diabliss - World's First Diabetic Friendly Cane Sugar

Diabetes – A global Epidemic

India – Diabetic

Capital of the

world!

A global epidemic

with significant

growth rates of

diabetes projected.

Diabetes rates

expected to double

world wide in next

20 years

Asia Diabetics % Diabetic North America Diabetics % Diabetic

India 85,923,733 7.1% United States 38,818,308 12.3%

China 60,931,800 4.5% Mexico 11,345,990 10.1%

Pakistan 13,882,616 7.6% Canada 4,066,503 11.6%

Indonesia 10,931,501 4.6% Puerto Rico 459,630 12.4%

Bangladesh 9,303,599 6.1%

Japan 9,297,280 7.3%

Philippines 6,186,636 6.7% Europe Diabetics % Diabetic

Korea, Republic of 5,354,958 9.0% Germany 9,839,160 12.0%

Thailand 5,076,322 7.7% France 6,166,870 9.4%

Malaysia 3,232,940 10.9% Turkey 5,596,426 7.4%

Viet Nam 2,574,620 2.9% Italy 5,235,959 8.8%

Spain 4,112,083 8.7%

Middle East Diabetics % Diabetic Poland 3,583,642 9.3%

Iran 4,714,873 6.1% United Kingdom 3,095,907 4.9%

Saudi Arabia 3,970,642 13.6% Argentina 2,695,740 6.0%

Iraq 2,599,740 7.8% Romania 1,599,676 8.4%

Morocco 2,497,580 7.6% Portugal 1,309,710 12.4%

Syrian Arab Republic 1,828,988 8.3% Netherlands 1,291,968 7.7%

Afghanistan 1,683,007 6.6% Greece 951,737 8.8%

United Arab Emirates 1,008,217 12.2% Austria 950,713 11.2%

Tunisia 916,088 8.5% Czech Republic 914,903 8.7%

Yemen 613,175 2.5%

Israel 567,510 7.1% South America Diabetics % Diabetic

Jordan 471,068 7.5% Brazil 14,258,480 6.0%

Kuwait 386,862 10.8% Colombia 2,255,424 4.8%

Lebanon 332,948 7.7% Venezuela 1,707,820 5.9%

Oman 307,856 11.1% Peru 1,706,608 5.6%

Qatar 254,976 13.3% Cuba 1,228,033 11.0%

Bahrain 177,778 14.4% Guatemala 1,065,248 6.9%

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Page 4: Diabliss - World's First Diabetic Friendly Cane Sugar

Diabetic Prevalence Rates in India Urban vs. Rural

General belief among leading medical professionals that WHO and other reports are

grossly underestimating the prevalence of diabetes in India due to poor detection and

prediction rates of diabetes from lifestyle factors

Rural India has significantly lower Diabetes prevalence rates due to lifestyle factors &

also due to poor detection

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Page 5: Diabliss - World's First Diabetic Friendly Cane Sugar

Diabetics – Recommended Regimen &

Lifestyle Constraints

Significant lifestyle constraints:

Severe diet restrictions

No Sugar

No Sweets

Diet low in carbohydrates

Limited (poor) food alternatives

Advised to consume 5-6 “mini meals” to manage swings

in blood sugar levels

Need to closely monitor blood sugar levels

Exercise 5 times per week

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Page 6: Diabliss - World's First Diabetic Friendly Cane Sugar

What is DiaBliss?

For the first time in the world we are able to render pure cane sugar diabetic

friendly:

DiaBliss is coming to you after 10 years of R&D and 4 years of product

performance testing among100s of diabetics

A colorless, odorless and tasteless herbal solution is extracted from 7-17 spices

including Turmeric, Black Pepper, Cinnamon, Ginger, Fenugreek, Gooseberry,

Pomegranate by using only water and no other chemicals or solvents .

DiaBliss system has limitless versatility: The herbal solution is blended with sugar

makes sugar diabetic friendly and allows glucose present in the blood stream to be

effectively absorbed by the body at a cellular level. The solution when blended

with rice renders carbohydrates diabetic friendly. Along the same lines, fruit based

foods and beverages have been blended with herbal solution to render them

diabetic friendly.

DiaBliss developed over 20 products which are being launched into retail FMCG

applications in a phased manner.

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Page 7: Diabliss - World's First Diabetic Friendly Cane Sugar

DiaBliss Herbal Solution –

Active Ingredients

Herbal solution contains a variety of active phytochemicals, including the

flavonoids, terpenoids, lignans, sulfides, polyphenolics, carotenoids, coumarins,

saponins, plant sterols, curcumins, and pthalides.

Many of these herbs contain potent antioxidant compounds that provide

significant protection against chronic diseases.

These compounds are known to have variety of health & wellness

characteristics - LDL cholesterol from oxidation, inhibit cyclooxygenase and

lipoxygenase enzymes, improve metabolism, enhance insulin sensitivity, inhibit

lipid peroxidation, or have antiviral or antitumor activity.

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Fenugreek

Turmeric Black Pepper

Ginger Cinnamon

Gooseberry Pomagranate

Page 8: Diabliss - World's First Diabetic Friendly Cane Sugar

Competitive Positioning - Sweeteners

Product Brand Names Composition/

Chemical Name

Manufacturing Process Taste Factors & Cooking Solutions Health Effects Calorific Value

Aspertame Equal, Nutra

Sweet

N-L-aaspartyl-L-

phenylalanine-l-methyl

ester (APM)

Fermentation and sysnthesis with

methanol with metal catalysts

Interacts with some foods and cannot

perfectly replace sugar, not thermally

stable

Aspartame must be avoided by people

with the genetic condition

phenylketonuria(PKU); Recent

packaging indicates not recommended

for children.

4 calories per

gram; 180 times

sweeter than

sugar

Sucralose Splenda,

Sugar Free

4-chloro-4-deoxy-.alpha.-

D-galactopyranosyl 1.6-

dichloro-1.6-dideoxy-

.beta.-D-fructo-

furanoside

Five Step Chemical Process

including chlorination of sucrose,

followed by high temperature, low

pH process for final conversion to

sucralose

There is still a distinct chemical taste

especially when products are used to

make sweets. Thermally stable and can

be used in almost all categories of foods &

beverages.

FDA & WHO evaluated over 100 studies

over 20 years and concluded the product

is generally safe. Recent packaging

indicates not recommended for

children.

No calorific

content

Saccharin Sweet' n Low,

Sweet Twin, and

Necta Sweet

2H-1λ6,2-benzothiazol-

1,1,3-trione

Two chemical synthesis processes Bitter after taste. Not thermally stable. Suspected Carcinogen (bladder cancer). 1 calorie per

gram, 10x

sweeter

Stevia Truvia, PureVia,

SweetLeaf

Sweetening ingredient -

Steviol glycosides. Class

of Compaounds fund in

Stevia plant leaf.

Minimal Processing for dark

colored stevia extracts. Crystalline

forms involves some level of

chemcal processing

Some level of bitter after taste; Can be

used for cooking and baking

Approved by FDA; Banned in some

European countries

4 calories per

gram; 200-400

times sweeter

than sugar

Levulose Dezire D-Frustose Some level of bitter after taste; Can be

used for cooking and baking; Indian

sweets have a distinct after taste

Fructose based products such as corn

syrup have been approved by FDA.

4 calories per

gram; Lower

Glycemic Index

than Sugar

Herbal Cane Sugar DiaBliss Cane Sugar blended with

herbal extracts

A colourless, tasteless and

odourless extract from 7 common

herbs and spices; Only water used

in preparation of herbal solution.

Only product that can claim exact same

taste of sugar; Thermally stable and can be

used in all categories of foods similar to

Sucralose.

HbA1c, Fasting and Post Pradial levels

show decreasing trends; Analysis and

animal studies indicate product is safe

for human consumption

4 calories per

gram; Lower

Glycemic Index

than Sugar

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Page 9: Diabliss - World's First Diabetic Friendly Cane Sugar

DiaBliss – Key Product Attributes

Natural Taste of Pure Cane Sugar with no after taste characteristics of sweeteners

High degree of product versatility in terms of usage in baking, cooking, low and

high temperature, wide pH ranges.

100% Natural - No chemicals in herbal extraction, only uses water in extraction

Only product that provides sugar, carbohydrate and fructose management system

thereby providing a complete and integrated approach to diabetic friendly foods

Content analysis, acute and sub-acute animal studies and histopathology studies on

animals indicate product is safe for human consumption.

Product showing positive efficacy in terms on long term blood sugar control (ie lower

levels of HbA1c, Fasting and Post prandial levels) in type 1 and type 2 diabetics

based on consumption periods from three months to three years.

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Page 10: Diabliss - World's First Diabetic Friendly Cane Sugar

Overall Process

Water based

extraction of

molecular values

Herbs & Spices

Herbal Extract

Herbal

Solution Blending

Ageing/

Drying Packaging

Sugar

(or Salt, Rice)

Primary Products

DiaBliss Sugar

DiaBliss Salt

DiaBliss Rice

Herbal

Solution Blending Processing Packaging

Ingredients

Derivative Products

DiaBliss Beverages(Lemon Tea, Lemon Juice, Instant Tea & Coffee Mix)

DiaBliss Prepared Foods ( Mixed Fruit Jam, Ketchup, Ravva Laddu Mix, Kesari Bath,

Gulab Jamun Mix, etc)

DiaBliss Cereals (Multigrain Porridge)

DiaBliss Chocolates (Dark, Milk & Filled)

DiaBliss Ice Cream Mixes (Vanilla, Mango)

Institutional Products (Bulk Packaging of DiaBliss Sugar & other products)

Sweet Chains

Bakeries

Hotels & Institutional

Food Companies

Beverage Companies

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Page 11: Diabliss - World's First Diabetic Friendly Cane Sugar

Product Performance Summary

Product Characterization @ SGS

labs, Chennai

Trials @ Sugen Life Sciences,

Tirupati

– Acute & Sub-Acute Toxicity studies

Summary of Product Usage &

Customer Testimonials

– Short Term Trials

– Long Term Trials

Product composition is safe for human

consumption based on heavy metals & pesticide

analyses.

No detrimental impact on animals health

parameters. Histopathological studies indicated

no organ impact when subject to accelerated

usage of product

GTT data indicates DiaBliss Sugar can be

classified as low glycemic index product

Extended GTT results with diabetic subjects

indicated excellent blood sugar control even with

high loading of DiaBliss sugar.

Data from diabetics who consumed product for

periods between 3 months to 36 months indicates

product is providing significant health benefits to

diabetics

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Page 12: Diabliss - World's First Diabetic Friendly Cane Sugar

DiaBliss Tackles all Metabolic Pathways

1. Starch to Sugar Conversion

2. Glucose Absorption

3. Glucose Tissue Uptake

4. Fat Reduction

5. Glucose Homeostasis*

6. Insulin Release

7. Insulin Sensitivity

* Glucose Homeostasis: the balance of insulin and glucagon to maintain blood

glucose; Glucagon: a fall in blood glucose increases the release of glucagon from the

pancreas to promote glucose production.

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Page 13: Diabliss - World's First Diabetic Friendly Cane Sugar

Acute Oral Toxicity with Wistar Rats

Page 14: Diabliss - World's First Diabetic Friendly Cane Sugar

Sub-Acute Oral Toxicity with Wistar Rats

Page 15: Diabliss - World's First Diabetic Friendly Cane Sugar

Typical HbA1c Profiles

Effective for Type 1 & Type 2

diabetics

15-50% reduction in HbA1c levels

Subjects report energetic feeling &

improved general wellness

Glycemic Index

Higher rate of metabolism

Low Glycemic Index Food (GI = 53 vs.

60 for normal sugar & 100 for

glucose)

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Page 16: Diabliss - World's First Diabetic Friendly Cane Sugar

Extended Glucose Tolerance Tests Conducted with diabetics

Excellent metabolism of

sugar by diabetics.

Sugar levels of normal

diabetics at or below

fasting levels in three

hours.

Two chronic alcoholics

(subjects 2 & 5) could

not metabolise at

satisfactory rates as

their liver and

pancreatic functions

already impeded.

Blood Sugar levels

dropped below fasting

levels for 70% of the

diabetics tested

indicating excellent

metabolic response

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Page 17: Diabliss - World's First Diabetic Friendly Cane Sugar

Fasting, PP & HbA1c Type 1 Diabetic

Type 1 diabetic, Age 58

9 months on DiaBliss Herbal cane sugar

40% reduction in HbA1c

0

50

100

150

200

250

4/3/2012 14/8/2012 15/9/2012 17/9/2012

Blo

od

Su

gar

Leve

ls, m

g/d

l

Type 1 Diabetic, Female, age 58 - Fasting & PP Profiles

Fasting

PP

Started consuming DiaBliss Herbal Cane Sugarfor Tea & Coffee

6

6.5

7

7.5

8

8.5

9

4/3/2012 6/6/2012 14/8/2012 17/9/2012H

bA

1c

Type 1 Diabetic, Female, age 58 - HbA1c Profile

Started consuming DiaBliss Herbal Cane Sugar for Tea & Coffee

* Blood Sugar levels measured at Mohan Diagnostics, Madurai

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Subject underwent

Fistula Operation

Page 18: Diabliss - World's First Diabetic Friendly Cane Sugar

Fasting, PP & HbA1c Type 2 Diabetic

Type 2 Diabetic, Age 63

18 months on DiaBliss herbal cane sugar

Lowered medication by 50%; Stabilized Fasting, PP & HbA1c swings

* Blood Sugar levels measured at Hi Tech Labs, Vadapalani, Chennai & Precision Labs, Adyar, Chennai

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Page 19: Diabliss - World's First Diabetic Friendly Cane Sugar

Juvenile Diabetic

8 year old juvenile

diabetic

Two years on

DiaBliss Sugar

Major lifestyle

improvement

Able to go to

school full-time

Able to enjoy all

kinds of foods &

sweets

Gaining body

weight without

significant increase

in insulin dosage

45% reduction in

HbA1c levels

* Blood Sugar levels measured at Priya Diagnostics, Besant Nagar, Chennai

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Page 20: Diabliss - World's First Diabetic Friendly Cane Sugar

Summary

For the first time in the world DiaBliss has been successful in making cane sugar

diabetic friendly

DiaBliss system provides unlimited food choices for diabetics, pre-diabetics and

wellness solutions for entire family

DiaBliss Sugar has been extensively tested and found to be safe for human

consumption.

Hundreds of diabetcs ranging in age from 8 to 82 (type 1, type 2) have

consumed DiaBliss Sugar for periods ranging from 3 months to 3+ years;

HbA1c, Fasting and PP levels tending to show lowering trends

DiaBliss has over 20 diabetic friendly and general wellness products spanning

various categories including primary foods, cereals, beverages, prepared foods,

chocolates, ice creams which will be introduced into the market in a sequential

manner.

Page 21: Diabliss - World's First Diabetic Friendly Cane Sugar

THANK YOU Contact:

www.diabliss.com

DiaBliss Consumer Products Pvt Ltd

1/283 ‘Shripuram’

Shripuram Road

Thoraipakkam

Chennai – 60097

Tamil Nadu

VR. Ramanathan, CEO

[email protected]

Tel: +91-9840427966

Siva Vallabhaneni, COO

[email protected]

Tel: +91-7760980631

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