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Diamond Detectors for Medical Dosimetry Jan U. Würfel , PTW-Freiburg, [email protected] CARAT Workshop, 13–15 December 2010

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Page 1: Diamond Detectors for Medical Dosimetry Jan U. Würfel, PTW-Freiburg, jan.wuerfel@ptw.dejan.wuerfel@ptw.de CARAT Workshop, 13–15 December 2010

Diamond Detectors for Medical Dosimetry

Jan U. Würfel, PTW-Freiburg, [email protected]

CARAT Workshop, 13–15 December 2010

Page 2: Diamond Detectors for Medical Dosimetry Jan U. Würfel, PTW-Freiburg, jan.wuerfel@ptw.dejan.wuerfel@ptw.de CARAT Workshop, 13–15 December 2010

Outline

Outline

Quick introduction to PTWQuick introduction to PTW

What a Diamond detector is used for

Some PTW test criteria for diamond dosemeters

Page 3: Diamond Detectors for Medical Dosimetry Jan U. Würfel, PTW-Freiburg, jan.wuerfel@ptw.dejan.wuerfel@ptw.de CARAT Workshop, 13–15 December 2010

Company Profile

Quick introduction to PTW

PTWPTW-Freiburg GmbH (1922) PTW-New York Corporation (1995)PTW-France SARL (2001) PTW-Asia Pacific Limited (2004)PTW-Latin America LTDA (2005)PTW-Beijing Limited (2007)PTW-UK Limited (2008)K&S Associates, Inc. (2009)

Sales, consolidated: 39.6 million €

Employees: approx. 260

More than 60 distributors worldwide

ISO 9001 and ISO 13485 certified

Page 4: Diamond Detectors for Medical Dosimetry Jan U. Würfel, PTW-Freiburg, jan.wuerfel@ptw.dejan.wuerfel@ptw.de CARAT Workshop, 13–15 December 2010

Employees

Quick introduction to PTW

100

120

140

160

180

200

220

Per

man

ent F

reib

urg

Em

ploy

ees

1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009

FreiburgNon-permanent Subsidiaries Total

2059

47

261

Page 5: Diamond Detectors for Medical Dosimetry Jan U. Würfel, PTW-Freiburg, jan.wuerfel@ptw.dejan.wuerfel@ptw.de CARAT Workshop, 13–15 December 2010

Calibration Laboratories

Quick introduction to PTW

PTW-Freiburg Secondary Standard Dosimetry Laboratory (SSDL) Accredited by PTB since 1979 Member of DKD and IAEA network 12,000 Chamber calibrations per year

K&S Associates Accredited Dosimetry Calibration Laboratory (ADCL) Accredited by AAPM since 1982 1,500 Chamber calibrations per year

Page 6: Diamond Detectors for Medical Dosimetry Jan U. Würfel, PTW-Freiburg, jan.wuerfel@ptw.dejan.wuerfel@ptw.de CARAT Workshop, 13–15 December 2010

Consolidated Turnover

Quick introduction to PTW

0,00

5,00

10,00

15,00

20,00

25,00

30,00

35,00

40,00

Mil

lio

n €

1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009

Page 7: Diamond Detectors for Medical Dosimetry Jan U. Würfel, PTW-Freiburg, jan.wuerfel@ptw.dejan.wuerfel@ptw.de CARAT Workshop, 13–15 December 2010

Product Overview

Quick introduction to PTW

Electrometers Ionization Chambers Detector Arrays Water Phantoms

X-Ray Test Tools OEM Components Calibration Benches Application Software

Page 8: Diamond Detectors for Medical Dosimetry Jan U. Würfel, PTW-Freiburg, jan.wuerfel@ptw.dejan.wuerfel@ptw.de CARAT Workshop, 13–15 December 2010

Outline

What a Diamond detector is used for

Quick introduction to PTW

What a Diamond detector is used forWhat a Diamond detector is used for

Some PTW test criteria for diamond dosemeters

Page 9: Diamond Detectors for Medical Dosimetry Jan U. Würfel, PTW-Freiburg, jan.wuerfel@ptw.dejan.wuerfel@ptw.de CARAT Workshop, 13–15 December 2010

Measurements in Water

What a Diamond detector is used for

Propagation and interaction of photons in water is very

similar to human tissue

Measurements in radiation therapy are performed in real

or artificial (plastic) water

The quantity we are looking for is: How much energy

per mass is deposited in water by the radiation?

Name: Absorbed Dose to water, Dw

Unit: 1 J/kg = 1 Gy

Page 10: Diamond Detectors for Medical Dosimetry Jan U. Würfel, PTW-Freiburg, jan.wuerfel@ptw.dejan.wuerfel@ptw.de CARAT Workshop, 13–15 December 2010

What Are We Actually Measuring?

What a Diamond detector is used for

Only very few photon interactions

The interacting photon transfers energy to an electron

The dose is deposited by these (“secondary”) electrons

Processes for this photon energy transfer in radiation therapy beams:

Photoelectric effect Compton effect Pair production

low energy

500 keV

high energy

25 MeV

Page 11: Diamond Detectors for Medical Dosimetry Jan U. Würfel, PTW-Freiburg, jan.wuerfel@ptw.dejan.wuerfel@ptw.de CARAT Workshop, 13–15 December 2010

Unfortunately...

What a Diamond detector is used for

Our detector is not made out of water

Photoelectric effect: mass attenuation coefficient ~ Z³ A detector with Z > Zwater will over-respond to scattered (low-energy) radiation.

This is called (bad) energy response

In large treatment fields (> 10x10 cm²) silicon detectors

(Z = 14) over-respond by several %.

Page 12: Diamond Detectors for Medical Dosimetry Jan U. Würfel, PTW-Freiburg, jan.wuerfel@ptw.dejan.wuerfel@ptw.de CARAT Workshop, 13–15 December 2010

What Happens at High Energies?

What a Diamond detector is used for

At high energies (> 1 MeV), the electron stopping power

ratio (detector / water) is the important quantity

Page 13: Diamond Detectors for Medical Dosimetry Jan U. Würfel, PTW-Freiburg, jan.wuerfel@ptw.dejan.wuerfel@ptw.de CARAT Workshop, 13–15 December 2010

What’s so Special about a Diamond Detector?

What a Diamond detector is used for

Type of detector

Size for same

response

@ Low

energy

@ High

energy

Air filled ionisation chamber

1 excellent

not perfect but

corrections available

Diode1000 x

smallerbad good

Diamond1000 x

smallergood good

The perfect detector is infinitesimally small and made out of water

Page 14: Diamond Detectors for Medical Dosimetry Jan U. Würfel, PTW-Freiburg, jan.wuerfel@ptw.dejan.wuerfel@ptw.de CARAT Workshop, 13–15 December 2010

Only One Type of Diamond on the Market

What a Diamond detector is used for

The PTW diamond detector is the only usable diamond detector

on the market

It’s a natural diamond

Limited resources (smaller than the market need)

Quite expensive

Page 15: Diamond Detectors for Medical Dosimetry Jan U. Würfel, PTW-Freiburg, jan.wuerfel@ptw.dejan.wuerfel@ptw.de CARAT Workshop, 13–15 December 2010

This is what a diamond detector is used for

What a Diamond detector is used for

PDD

Profile

Linac

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-100 -50 0 50 100Pos [mm]

Sig

nal [

%]

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0 50 100 150 200 250 300 350Depth [mm]

Sig

nal [

%]

Page 16: Diamond Detectors for Medical Dosimetry Jan U. Würfel, PTW-Freiburg, jan.wuerfel@ptw.dejan.wuerfel@ptw.de CARAT Workshop, 13–15 December 2010

Diamond “Quality” Depends on its intended Use

What a Diamond detector is used for

A diamond detector may react very fast to a single particle event

but very slow to high-flux radiation therapy photons

(mean flux density roughly 1010 1/(cm²s))

Reaction to 30 keV X-rays can be completely different from

reaction to 1 MeV gamma radiation. This includes response,

priming (= pumping), and speed of response

Page 17: Diamond Detectors for Medical Dosimetry Jan U. Würfel, PTW-Freiburg, jan.wuerfel@ptw.dejan.wuerfel@ptw.de CARAT Workshop, 13–15 December 2010

Outline

Some PTW test criteria for diamond dosemeters

Quick introduction to PTW

What a Diamond detector is used for

Some PTW test criteria for diamond dosemetersSome PTW test criteria for diamond dosemeters

Page 18: Diamond Detectors for Medical Dosimetry Jan U. Würfel, PTW-Freiburg, jan.wuerfel@ptw.dejan.wuerfel@ptw.de CARAT Workshop, 13–15 December 2010

Priming (Pumping)

Some PTW test criteria for diamond dosemeters

0.0

0.1

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0.8

0 200 400 600 800 1000 1200t [s]

I [nA

]

Natural diamond, Co-60, 6.77 mGy/s

Dose for priming: when final signal ±0.5 % is reached

Here: 5 Gy

Page 19: Diamond Detectors for Medical Dosimetry Jan U. Würfel, PTW-Freiburg, jan.wuerfel@ptw.dejan.wuerfel@ptw.de CARAT Workshop, 13–15 December 2010

Speed of Response

Some PTW test criteria for diamond dosemeters

Reaction to beam-on and -off:

Signal rise: 99 % reached within 2 s

Signal drop: 1 % reached within 2 s

0.00

0.20

0.40

0.60

0.80

1.00

1.20

1485 1495 1505 1515 1525 1535 1545 1555 1565 1575 1585t [s]

I [nA

]

Page 20: Diamond Detectors for Medical Dosimetry Jan U. Würfel, PTW-Freiburg, jan.wuerfel@ptw.dejan.wuerfel@ptw.de CARAT Workshop, 13–15 December 2010

Signal to Dark Current Ratio (SDR)

Some PTW test criteria for diamond dosemeters

NOT the same as Signal to noise ratio (SNR)

SDR_2s 100

SDR_1min 1000

0.000

0.001

0.010

0.100

1.000

3030 3040 3050 3060 3070t [s]

I [nA

]

SDR_2s

SDR_1min

Page 21: Diamond Detectors for Medical Dosimetry Jan U. Würfel, PTW-Freiburg, jan.wuerfel@ptw.dejan.wuerfel@ptw.de CARAT Workshop, 13–15 December 2010

Why is the Speed of Response so Important?

Some PTW test criteria for diamond dosemeters

A slow speed can lead to tilted shoulders in profile measurements

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Sig

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scan direction

Page 22: Diamond Detectors for Medical Dosimetry Jan U. Würfel, PTW-Freiburg, jan.wuerfel@ptw.dejan.wuerfel@ptw.de CARAT Workshop, 13–15 December 2010

Radiation Hardness?

Some PTW test criteria for diamond dosemeters

Diamond is less sensitive to radiation damage than silicon

But is it fully radiation resistant to 25 MV Linac radiation?

Page 23: Diamond Detectors for Medical Dosimetry Jan U. Würfel, PTW-Freiburg, jan.wuerfel@ptw.dejan.wuerfel@ptw.de CARAT Workshop, 13–15 December 2010

Re-Priming Effect

Some PTW test criteria for diamond dosemeters

For artificial diamond dosemeters it can happen that after a

break of a few minutes, re-priming is necessary

This can lead to tilted shoulders

Re-priming dose after 3 min pause should be below 100 mGy

Page 24: Diamond Detectors for Medical Dosimetry Jan U. Würfel, PTW-Freiburg, jan.wuerfel@ptw.dejan.wuerfel@ptw.de CARAT Workshop, 13–15 December 2010

Thank You for Your Attention

The End