discontinuity between suicide attempts and completed suicide implications for prediction angus h...
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DISCONTINUITY BETWEEN SUICIDE ATTEMPTS AND
COMPLETED SUICIDEImplications for Prediction
Angus H Thompson
Dept of Public Health, Flinders University
EVIDENCE FOR DISCONTINUITY
• Many Attempters do not wish to die
• Very few attempters take their own lives
• There are some differences between the two groups
SINGLE DIMENSION MODEL
Thoughts of Death
Suicidal Thoughts
Plans/Serious Ideation
Suicide Attempts
Completed Suicide
SINGLE DIMENSION MODEL
• Attempts signify higher risk
• Escalation in lethality if no resolution
• Observed differences between the two may
be due to differences in escalated intensity
PREDICTION OF SUICIDE
Too Rare to be Usefully Predicted?
• About 11 per 100,000 in Australia and Canada currently
(< 1 Ninetieth of one percent)
STUDY 1
Canadian University Students
N = 227
65% Female
STUDY 1Q1 Has there ever been a period when
you felt like you wanted to die?
Q2 Have you ever felt so low you thought of committing suicide?Q3 Have you ever made definite plans to
commit suicide (even though you did
not actually make an attempt)?Q4 Have you ever attempted suicide?
Persons at a particular level who also displayed a “lower” level of suicidal behaviour
“Preceded” by:
Index Level Plan Suic Tht Death Wish
Attempt 91% 100% 100%
Plan 100% 100%
Suic Thought 96%
RESULTS
The frequency of acknowledgement of each level of suicidal behaviour
NoneDeathWish
SuicideWish Plan Attempt
108(48%)
115(51%)
80(35%)
26(12%)
12(5%)
RESULTS
IMPROVING PREDICTION 1
• Annual Rate (then) 0.014%
• Lifetime Ideator rate 1.18%
• Lifetime (40 Yr) rate 0.56%
STUDY 2
COMMUNICATION OF INTENT/ATTEMPTS
• Review: Psychological Autopsy Studies
• Suicides with Prior Communication and Attempts
STUDY 2
Premise:
If an attempt is often a means of communication, then attempts should be considered along with other forms of expression of suicidal intent for the purposes of prediction and understanding.
COMMUNICATION INCLUDES:
• Direct Statements
• Dire Predictions, Allusions to Being Better off Dead, Expressing a Wish to be Dead
PSYCHOLOGICAL AUTOPSY STUDIES
N % Male Age AttemptCommIntent
Attempt &Comm‡
Robins et al. 134 77% Broad 22% - 69%
Wroblenski & McIntosh
112 76% Broad 92%
Rich et al. 283 82% <30/30+ 42/35% - 71/63 %†
Åsgård 104All
female Broad 63% 59% 97%
Runeson 58 72% 15-29 66% 78%
Heila et al. (Schizophrenia)
73 77% Broad 52% 84%
Heila et al. (No Schizophrenia)
1065 77% Broad 55% 70%
† This, assuming that attempts were included (underestimate?).‡ Median = 75%
Thus, on “average” 75% of suicides were preceded by a communication of intent (Range: 63%-97%)• Conservative? All key informants?
• Conservative? Drop low scores?
• Liberal? Retrospective bias?
• Not a predictive value (how many communicators complete?
Studies Lifetime Year 1Post Yr 1(per year)
Sakinofsky (2000) 28 1.61% .47%
Owens et al. (2002) 90 1.80% .47%
Maris (1992) 10-15%
PROPORTION OF ATTEMPTERS WHO COMPLETE
ESTIMATING THE PROPORTION OF COMMUNICATORS WHO COMPLETE
Assume the Ratio of Communicators (Including Attempters) to Attempters Only Among Completed Suicides (1.69) is the Same AmongAll Showing Parasuicidal Behaviour
We Have Estimates of the Interrelationships of:Death Wishes, Ideation, Attempts & Suicides – but Without Communication of Intent…
PREDICTION OF OUTCOMES
PREDICTED VALUES
PREDICTORS Thoughts PlansCommun.
IntentDeath1st-Yr.
DeathLifetime
DEATH WISH 67.0% 22.8% 17.6% 0.32% 1.76%
PREDICTION OF OUTCOMES
PREDICTED VALUES
PREDICTORS Thoughts PlansCommun.
IntentDeath1st-Yr.
DeathLifetime
DEATH WISH 67.0% 22.8% 17.6% 0.32% 1.76%
SUICIDALTHOUGHTS
32.9% 25.4% 0.46% 2.54%
PREDICTION OF OUTCOMES
PREDICTED VALUES
PREDICTORS Thoughts PlansCommun.
IntentDeath1st-Yr.
DeathLifetime
DEATH WISH 67.0% 22.8% 17.6% 0.32% 1.76%
SUICIDALTHOUGHTS
32.9% 25.4% 0.46% 2.54%
PLANS 65.1% 1.17% 6.51%
PREDICTION OF OUTCOMES
PREDICTED VALUES
PREDICTORS Thoughts PlansCommun.
IntentDeath1st-Yr.
DeathLifetime
DEATH WISH 67.0% 22.8% 17.6% 0.32% 1.76%
SUICIDALTHOUGHTS
32.9% 25.4% 0.46% 2.54%
PLANS 65.1% 1.17% 6.51%
COMMUN.OF INTENT
5.14% 28.56%
PREDICTION OF OUTCOMES
PREDICTED VALUES
PREDICTORS Thoughts PlansCommun.
IntentDeath1st-Yr.
DeathLifetime
DEATH WISH 67.0% 22.8% 17.6% 0.32% 1.76%
SUICIDALTHOUGHTS
32.9% 25.4% 0.46% 2.54%
PLANS 65.1% 1.17% 6.51%
COMMUN.OF INTENT
5.14% 28.56%
MORTALITY DUE TO SUICIDE(% of All Deaths)
2000 2001 2002 2003
Canada 1.7 1.7 1.7 1.7
Australia 1.8 1.9 1.7 1.7
ARE THERE RISK FACTORS?
• Most cases are captured in Death Wishes
• We need to identify precursors of the first death wish
• We need to know what prevents movement to the next level of intensity
HONING PREDICTION
• Distal prediction is relatively low because of many false positives. Distal nature and absence of negatives make it ideal for population and health promotion approaches
• Proximal prediction is much higher, but late in the game. Lower false positives. Suited for clinical and individually-based services
IMPROVING PREDICTIONMatching Activity & Predictability
1. Primary Prevention
2.Early Detection/Intervention
3.Crisis Intervention / Rx
IMPROVING PREDICTIONMatching Activity & Predictability
1. Primary Prevention Population Focus 1.7%
2.Early Detection/Intervention
3.Crisis Intervention / Rx
IMPROVING PREDICTIONMatching Activity & Predictability
1. Primary Prevention Population Focus 1.7%
2.Early Detection/InterventionDeath Wish/ Ideation 1.7% - 2.5%
3.Crisis Intervention / Rx
IMPROVING PREDICTIONMatching Activity & Predictability
1. Primary Prevention Population Focus 1.7%
2.Early Detection/InterventionDeath Wish/ Ideation 1.7% - 2.5%
3.Crisis Intervention / RxPlans/Communication 6.5% - 29%
IMPROVING PREDICTIONProblem Synthesis
• Social problems are interrelated: Common base?
• Preventing one will prevent others
• Common Underlying Factors
Childhood Trauma Brain Development
Substance Abuse Secure Attachment
Neglect / Abuse
Heredity (Serotonin)
Optimism / Helplessness
IMPROVING PREDICTIONAdding Risk/Protective Factors
• Focus on PrecursorsChildhood Trauma Brain DevelopmentSecure Attachment Neglect / Abuse
Punishment as Suppressant
• Focus on Trajectory ModifiersCoping Strategies Social SupportGene Action TreatmentRandom Acts Transitions
WHEN I GET TO BE DICTATOR …
For More Information:
Angus H ThompsonDept of Public Health, Flinders University
www.socialproblemindex.com
Many Thanks
Serotonin Transporter GeneExperience in Early Life - Depression
Age 26
No Abuse Moderate Abuse Severe Abuse
.30
.50
.70
A. Caspi, Science, 18 July 2003, Vol 301.
Depression Risk
LL
SS
SL
S = Short Allele L = Long Allele
Founders Network
The frequency of acknowledgement of each level of suicidal behaviour
NoneDeathWish
Ideation Plan Attempt
Total 108 (48%) 115 (51%) 80 (35%) 26 (12%) 12 (5%)
MostSerious
108 (48%) 38 (17%) 52 (23%) 16 (7%) 12 (5%)
RESULTS