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Projections and Realized Results are specific to the institution where they were obtained and may not reflect the results achievable at other institutions.

70%70% reduction in total cleaning time from the standard tray

Savings of 18.8 minutes per 8 hrs

Savings of 56.4 minutes per 24 hrs

Gaining Efficiencies with an Anti-Static Waste Tray on HistoCore Rotary Microtomes• Summary: The cleaning process of a paraffin tray can

add up to a significant amount of time and resources each day. A new anti-static tray was designed to resist the adhesion of paraffin sections to the tray and allow for ease of cleaning.

• Primary Action: Conducted research to measure the different time measurements between the following methods: cleaning a standard paraffin tray; cleaning a standard paraffin tray with wet paper towels; and cleaning the anti-static tray.

• Outcome: Implementation of an anti-static waste tray enabled a 70% reduction in total cleaning time versus a standard waste tray, potentially resulting in a savings of 56.4 minutes per 24 hours, per microtome.

28%Blocks per

Hour

Savings of 1040 hours annually

Optimizing Anatomical Pathology Through Implementation of Specimen Tracking• Summary: The Leica Biosystems Content & Evidence

Team partnered with a major academic medical center to examine ways to optimize their anatomic pathology lab, increase efficiency and drive patient safety.

• Primary Action: Designed an automated solution to help achieve the goals of patient safety and efficiency, while becoming a leader in anatomic pathology through technology and process improvement.

• Outcome: Increased blocks processed per hour by 28%, saved 1040 hours (annual).

67%reduction in hands-on time

Increasing Routine Staining Productivity & Throughout Through Automation• Summary: The Leica Biosystems Content &

Evidence Team partnered with a large province-based hospital to review the impact of automating their routine staining area.

• Primary Action: Replacing linear staining system with detached coverslippers with 2 HistoCore SPECTRA Workstations.

• Outcome: Reduced hands-on time requirements by 67%, in turn, helping to increase laboratory capacity.

85.2%85.2% decrease in mean number of touches per run

14.5%14.5% mean decrease in hands-on time per run

Optimizing Efficiency Through Automation in H&E Staining• Summary: The Leica Biosystems Content & Evidence

Team partnered with Wisconsin Diagnostics to evaluate and optimize routine staining & coverslipping efficiency through automation.

• Primary Action: Complete pre- and post-automation time benchmarks, to determine laboratory savings of transportation, motion, wait time and talent.

• Outcome: Decreased mean number of touches per run by 85.2%. Decreased hands-on time per run by 14.5%.

Addressing Opportunities for Improving Care Cadence by Driving Interdepartmental Collaboration• Summary: The Leica Biosystems Content & Evidence Team partnered

with Southern Ohio Medical Center (SOMC) to analyze and drive the cadence of care processes across radiology, pathology and surgery to reduce patient delays and outmigration.

• Primary Action: Improved coordination through departments by optimizing patient scheduling, identifying and aligning on common goals across departments and providing timely data to drive patient coordination and prioritization.

• Outcome: Reduced days from screening to diagnostic mammogram from 21.8 days (2017) to 6.5 days (2018).

of time

Reduced to

29.8%

Optimization of Staff and Equipment to Boost Throughput• Summary: The Leica Biosystems Content & Evidence Team

has partnered with a major academic facility within an Integrated Network to examine how to optimize staffing and equipment in their immunohistochemistry lab.

• Primary Action: Analyzed client’s needs, aligned ordering patterns to processing requirements and created a “split shift” with two techs.

• Outcome: Enabled distribution of 50% more cases to pathologists.

more cases distributed topathologists

50%

50%increase in

capacity for 8 hour period

Increasing Capacity Through Optimizing the Laboratory Layout• Summary: The Leica Biosystems Content & Evidence Team partnered

with an academic medical center to examine how to optimize their anatomical pathology space and equipment.

• Primary Action: Leica team created a proposal for renovated space, based on clinical and process expertise.

• Outcome: Increased laboratory capacity for 8-hour period by 50%.

70%70% decrease in days for Mammography results

Identifying Process Improvements in Breast Imaging• Summary: The Leica Biosystems Content & Evidence

Team partnered with a customer to evaluate the opportunities for process improvement throughout their breast imaging department.

• Primary Action: Through sharing data on national metrics, reinforced through observational data on internal processes, team was able to implement lasting change.

• Outcome: Realized 70% decrease in days for mammography results.

Gastroenterology Laboratory Reduces TAT by 42% by Eliminating 25% of Touchpoints• Summary: A growing gastroenterology group was looking

to double the number of clinics within its network by the end of 2019, while maintaining quality and turn-around time.

• Primary Action: Working with lab management, the team extended current staffing schedule and aligning processing activities to “just in time” practice.  Aligned the time of day that patient samples are received, accessioned and grossed.

• Outcome: Realized reduction in lab turnaround time by 42% while reducing process steps by 25%.

25%

42%

reduction in process steps

reduction in turnaround time

Reduced time required from

imaging to final

28.7%Expediting Patient Care Through Improved BI-RADS Finalization• Summary: The Leica Biosystems Content & Evidence Team

conducted process assessments to analyze the timely treatment for breast cancer patients with Southern Ohio Medical Center (SOMC).

• Primary Action:  A multi-disciplinary team of process and SOMC clinical experts implemented the following actions:  utilization of lean principles for patient management, coordination of staff and radiologist schedules, standardized process for prior authorizations and confirmation of appropriate metrics.

• Outcome:  Reduced time required from imaging BI-RAD of 0 to a final BI-RAD rating of 0 from average of 26.10 days (2018) to 7.5 days (2019).

Case Base Versus Singe Piece IHC Workflows Evaluated in a Large Reference Laboratory• Summary: The Leica Biosystems Content &

Evidence Team partnered with a high-volume reference laboratory to evaluate the potential impact of case based IHC workflow versus individual slide workflow.

• Primary Action: Observation of IHC protocols, staining instrument utilization and case completion process.

• Outcome: Case base model reduced total hands on time, demonstrating a 69% reduction in hands-on time.

69%reduction in hands-on time

Increasing Staining Capacity Through Optimizing Use of Instrumentation• Summary: The Leica Biosystems Content & Evidence Team

partnered with a Province-based hospital to examine how to optimize IHC department, specifically to accommodate a growing volume of IHC Stains.

• Primary Action: Integrate LIS with IHC instrumentation while creating a split shift, combining responsibilities from two current positions.

• Outcome: Increased IHC capacity by 50%, from 120 to 180 slides daily.

50%Increased

IHC capacity

from 120 to 180 slides daily

Benefits of Implementing a Specimen Tracking System (STS) in Anatomic Pathology• Summary: The Leica Biosystems Content & Evidence

Team partnered with CPA Labs, over a three-year period, to understand the impact of implementing automation of specimen tracking combined with workflow optimization.

• Primary Action: Implemented, optimized and measured impact of automated specimen tracking system.

• Outcome: Reduced hands-on time processing requirements by 76.5%, across entirety of workflow.

Optimizing Microtomy, Case Assembly and IHC Testing Through Implementation of Automated Specimen Tracking• Summary: The Leica Biosystems Content & Evidence

Team partnered with a private, multispecialty clinic to assess the impact of implementing automated specimen tracking.

• Primary Action: Implementation of an automated specimen tracking system to assist with eliminating use of LIS reports while changing labeling and slide creation process to a safer on-demand process.

• Outcome: Implementation of an automated specimen tracking system would enable a 14.1% reduction of hands-on time in microtomy while saving approximately 1432 hours/year through elimination of manual tasks.

14.1%reduction of hands-on time in microtomy

177%Improvement in

Slides Ready for QC

Reducing Batch Size to Improve Slide Turnaround Time• Summary: The Leica Biosystems Content & Evidence Team

partnered with Queen Elizabeth Hospital to examine how to optimize their processes to reduce turnaround time.

• Primary Action: Reduced batch sizes from embedding to case assembly in order to decrease wait times and result in slides being completed earlier.

• Outcome:  Realized 177% improvement in slides ready for QC.

19.3%Reduction

of Outmigration

Potential to Improve Patient Care Through Identifying Inefficiencies• Summary: The Leica Biosystems Content & Evidence Team

partnered with a private teaching hospital to improve surgical timeliness, improve efficiency for breast needle localizations and reduce outmigration.

• Primary Actions: Identified needle localizations as root cause for surgical delays. Alignment of start times for localizations were instituted. Optimization of biopsy procedure.

• Outcome: Projected outcomes include: decrease in number of days from biopsy to initial surgery – currently at 31 days, decrease in number of days from biopsy to adjuvant therapy – currently at 68 – 77 days and reduction of outmigration percentage – currently at 19.3%.

Optimizing Process Workflow Through Layout Redesign• Summary: The Leica Biosystems Content & Evidence

Team partnered with a private, non-profit, integrated health system to optimize their new laboratory layout to ensure efficient process flow.

• Primary Action: Mapped the process flow and redesigned the layout to rearrange the placement of process steps and equipment.

• Outcome: Elimination of crossover process steps and optimization of layout enabled 44.2% reduction in travel.

44.2%reduction intravel

81%Total

Hands-on Time Reduction

40%Hands-onTech TimeReduction

Using Lean Tools to Identify Inefficiencies in IHC Processing• Summary: The Leica Biosystems Content & Evidence

Team partnered with a medical university to examine how to optimize their IHC lab.

• Primary Action: Eliminating hand-writing, paper and relabeling, the complexity of processing slides was reduced.

• Outcome: Reducing hand-writing and paper, along with standardization to a single IHC platform, hands-on tech time was reduced by 40% versus existing processes. By eliminating additional steps, such as multiple labeling, hands-on time further reduced, bringing total hands-on time reduction by 81%.

72%Tech

Maintenance Time Drops

46%Reduction of

Reagent Costs

55%FootprintOptimized

Optimizing Automated Tissue Processing Efficiency to Reduce Cost• Summary: The Leica Biosystems

Content & Evidence Team worked with a world-renowned, large medical center pathology lab to evaluate operating efficiency of automated tissue processing.

• Primary Action: Through benchmarking current practices and performing a capacity analysis, identified opportunity for instrument utilization and maintenance standardization.

• Outcome: Standardization to dual-retort automated processors would help reduce reagent costs by 46%, tech maintenance time by 72% and footprint reduction by 55%.

Through our comprehensive portfolio, our vision is to enable clinicians to efficiently provide patients a highly confident diagnosis within 24-hours from biopsy

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