Diseases of the Urinary System

Dee Dee Schumacher C.V.T.,V.T.S.(ECC), M.Ed.Casey ConwayJeannie Stall R.V.T.Google Images/ClipArtAlleice Summers

Feline Lower Urinary Tract Disease (FLUTD)

• AKA feline cystitis, FUS• Cause : Unknown• Appears to be self-limiting in most cats (according to

book)• Symptoms: Hematuria, > frequent urinations

Dysuria (painful urination),Inappropriate urination

• Dx: U/A, urine culture, x-rays• Tx: Only use abx if necessary, change diet, use anti-

inflammatory meds w/ caution• May be recurring problem, there is no definitive cure

Canine Cystitis

• Bacterial urinary tract infection is the most common cause

• Symptoms: Increased frequency of urination, Hematuria, Dysuria,

Frequent licking of the urethral area

• Dx: U/A , urine culture• Tx: abx based on culture & sensitivity, Acute – tx for 10-14 days Chronic- tx for 4-6 weeks• Relapses are common due to inadequate treatment

Feline UrolithsMulti-crystalline concretions composed of minerals w/ a sm. amt. of

matrix ( mucoprotein )AKA “bladder stones” (may be located anywhere in the urinary tract)• Radiopaque or radiolucent • Obese, older cats appear to be predisposed • Small uroliths can become lodged in the urethra (obstruction)Symptoms depend on degree of trauma, obstruction

– Hematuria– Dysuria– Inappropriate urination – Straining to pass urine– Vomiting– Collapse– Death

• May be asymptomatic

Feline Uroliths

• Dx: x-rays, ultrasound, PE• Tx: diet that alters urine pH and dissolves

uroliths for 4-8 weeks, abx• Surgical treatment – cystotomy, uroliths

Obstruction – must unblock urethra asap, supportive therapy

PU (perineal urethrostomy): If uroliths can’t be removed from urethra

Feline Urethral Plugs

• Consist of small, varying amts. of minerals w/ large amt. of matrix( mucoproteins)

Same factors associated w/ formation of uroliths• Symptoms:

– Straining to urinate– Vomiting– Dehydration– Collapse

• Dx: bladder is enlarged & firm on palpation, hx, x-rays, bloodwork- increased BUN, CREA, Phos. levels

Feline Urethral Plugs

• Must reestablish urethral patency asap!

• In azotemic cats, less anesthesia is necessary

• Do not perform cystocentesis until unblocked!

Urolithiasis - Canine

• Studies indicate prevalence < 1% in dogs

• Uroliths form in urine supersaturated with specific substances – minerals

• After formation – may pass out urinary tract, continue to grow in the tract, dissolve, or become inactive

• Clin.signs: Dysuria, hematuria

Urolithiasis - Canine

• Dx: u/a, x-rays, labwork, stone analysis

• Tx: change diet, abx, surgical removal, urohydropropulsion

Urolithiasis - Canine

Renal Failure

• Filtration & waste management of the body• Reduction in blood flow or damage to the nephron

results in renal failure – acute or chronicNephron unit is damaged & glomerular filtration declines,

resulting in azotemia (build-up of toxins in body)• Clin. Signs: Acute – oliguria, polyuria, fever, kidneys

painful on palpation, v/d, anorexia, dehydration• Dx: Phys. exam, Hx, U/A, blood work• Tx: IV fluids, discontinue nephrotoxic drugs, intestinal

protectants, diuretics• May improve renal function, it may never return to

completely normal levels, prognosis can be guarded

Chronic Renal Failure

Common in older pets, irreversible & progressive decline in renal function, months to years

• Cats more affected than dogs

• Clin.signs: Dullness, lethargy, weakness, wt. loss, anorexia, v/d, polyuria, polydipsia, gait disturbances in cats, sudden blindness

Chronic Renal Failure

• Dx: labwork

• Tx: Supportive care & correction of imbalances-dehydration, electrolytes, GI symptoms

• IV or SQ fluids,

diuretics, consider

euthanasia ???

Urinary Incontinence

• Frequent in older pets• Loss of voluntary control of urination• Multiple causes: Neurologic, obstruction, bladder disease, hormone levels• Clin. Signs: Owner reports pet “leaks” when asleep or exercising, perianal area is always wet• Signs of concurrent UTI are present• Older ,SF, intact males predisposed• Dx: u/a, x-rays, bloodwork• Tx: based on determination of specific cause• Phenypropanolamine (PPA)

Equine

• Cystitis – inflammation of the bladder,

rare, dx same, tx same

• Urinary bladder prolapse – postpartum mares, replace bladder, avoid rupture, abx

• Incontinence – diff to treat, tx is usually symptomatic, urine scald

• Urolithiasis – rarely cause obstruction, if do- male horse, removal

Urolithiasis – Sheep & Goats

• Most commonly seen in wethers, rams, bucks that are on high-concentrate diets

• Common in feedlot & pet animals

• Similar clin. signs

• Dx: clin. signs, u/a, x-rays

• Tx: Amputate urethral process, cystotomy, urinary acidifiers

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