dna and genomes
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DNA and genomes. DNA and genomes. The phosphate groups have pKas of around 2 and around 7. This means DNA is negatively charged in the cell. The phosphate groups and the OH of the deoxyribose make the DNA exterior hydrophilic. - PowerPoint PPT PresentationTRANSCRIPT
![Page 1: DNA and genomes](https://reader036.vdocument.in/reader036/viewer/2022062309/56814627550346895db334a9/html5/thumbnails/1.jpg)
DNA and genomes
![Page 2: DNA and genomes](https://reader036.vdocument.in/reader036/viewer/2022062309/56814627550346895db334a9/html5/thumbnails/2.jpg)
DNA and genomes
The phosphate groups have pKas of around 2 and around 7.
This means DNA is negatively charged in the cell.
The phosphate groups and the OH of the deoxyribose make the DNA exterior hydrophilic.
The bases are almost water insoluble but with the possibility of hydrogen bonds.
![Page 3: DNA and genomes](https://reader036.vdocument.in/reader036/viewer/2022062309/56814627550346895db334a9/html5/thumbnails/3.jpg)
DNA structure
![Page 4: DNA and genomes](https://reader036.vdocument.in/reader036/viewer/2022062309/56814627550346895db334a9/html5/thumbnails/4.jpg)
![Page 5: DNA and genomes](https://reader036.vdocument.in/reader036/viewer/2022062309/56814627550346895db334a9/html5/thumbnails/5.jpg)
![Page 6: DNA and genomes](https://reader036.vdocument.in/reader036/viewer/2022062309/56814627550346895db334a9/html5/thumbnails/6.jpg)
DNA structure
![Page 7: DNA and genomes](https://reader036.vdocument.in/reader036/viewer/2022062309/56814627550346895db334a9/html5/thumbnails/7.jpg)
DNA structure
![Page 8: DNA and genomes](https://reader036.vdocument.in/reader036/viewer/2022062309/56814627550346895db334a9/html5/thumbnails/8.jpg)
chromatin
![Page 9: DNA and genomes](https://reader036.vdocument.in/reader036/viewer/2022062309/56814627550346895db334a9/html5/thumbnails/9.jpg)
Figure 4.11
![Page 10: DNA and genomes](https://reader036.vdocument.in/reader036/viewer/2022062309/56814627550346895db334a9/html5/thumbnails/10.jpg)
Figure 4.12
![Page 11: DNA and genomes](https://reader036.vdocument.in/reader036/viewer/2022062309/56814627550346895db334a9/html5/thumbnails/11.jpg)
Figure 4.13
![Page 12: DNA and genomes](https://reader036.vdocument.in/reader036/viewer/2022062309/56814627550346895db334a9/html5/thumbnails/12.jpg)
Figure 4.20
![Page 13: DNA and genomes](https://reader036.vdocument.in/reader036/viewer/2022062309/56814627550346895db334a9/html5/thumbnails/13.jpg)
Size and organization of genomes
Different organisms have different amounts of haploid DNA and the correlation with complexity of the organism is poor.
Organization of the human genome
• Repetitive DNA makes up over 50% of the human DNA and the protein coding regions only about 2%.