dna structure & function. perspective they knew where genes were (morgan) they knew what...
TRANSCRIPT
DNA Structure & Function
Perspective
They knew where genes were (Morgan)They knew what chromosomes were made of Proteins & nucleic acids
They didn’t know which one was the gene Better case for proteins
The DNA Structure
Watson and Crick Used model
exploration
Rosalind Franklin X-ray crystallography
Chargaff’s rule A-T; G-C
DNA Replication
Life reproduces itself
Genes (DNA) are inherited
How does the structure of DNA make it easy to replicate itself for cell division?
DNA Replication
Cloning
Genes: How they work
Review the flow of information from DNA RNA proteinAll our traits that are expressed (physical, biological, and chemical) is produced by proteins
Genes: How they work
The Genetic Dictionary
Transcription
RNA Processing
Translation
How does the codon on mRNA get translated into an amino acid?
Adapter molecule?
Transfer RNA (tRNA)
Translation
Translation
MutationsKnowing the genetic code help us understand inherited disorders
A single genetic mutation
Mutations
Any change in the nucleotide sequence of DNA
Note: the DNA sequence is not shown here but the RNA and amino acid sequence is represented
Mutations
Base-substitutions can sometimes lead to a beneficial changeIt’s these beneficial changes that can lead to better adaptations and evolution of new species
Mutations
Mutations are the only source of new genetic material
The diversity of life around us is due in large part to random mutations of the DNA nucleotide sequence