DNA structure II

• DNA• Composition of DNA • Evidence for genetic material • Structure • Implications of the structure

DNA & Nucleotides

DNA and RNA nucleotides

Evidence for genetic material: Griffith transformation

Evidence for genetic material:Avery

Hershey- Chase expt

Structure

Base Pairing Rules

Watson-Crick Model

Structure

• The double helix • base pairing rules • anti-parallel strands • bases/turn • major and minor

groove

Models

B= low saltA= high saltZ DNA= left, 12 bases/turn

B-DNA A-DNA Z-DNA

Properties of DNA

Implications of the structure

• DNA replication

• Genetic Information stored in DNA molecule