doe’s genomics:gtl program a protein production and molecular tag facility for california
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DOE’s Genomics:GTL Program A Protein Production and Molecular Tag Facility for California. Briefing to CCST February 1, 2006 Dr. Leonard M. Napolitano, Jr. Sandia National Laboratories Livermore, CA. - PowerPoint PPT PresentationTRANSCRIPT
Briefing to CCSTFebruary 1, 2006
Dr. Leonard M. Napolitano, Jr.Sandia National Laboratories
Livermore, CA
DOE’s Genomics:GTL ProgramA Protein Production and
Molecular Tag Facility for California
California has the opportunity to obtain federal funding for a next-generation biotech facility. Facility would develop new technologies, processes,
and materials to advance proteomics - the next life sciences frontier
Facility products and knowledge would anchor California’s expertise and prestige in this critical area
Because of proximity, California companies and researchers would be ideally positioned to benefit from this user facility
Allies and supporters that help develop the facility will have first-hand access to new knowledge
DOE’s Genomics:GTL Program aims to develop biological solutions to energy problems.
Proteomics is the next frontier in biological understanding and application.
DNA Proteins
the “blueprint” the tools
RNA
Biological pathways/cells:
the assembly lines and factories
DOE wants to build capital facilities to support their mission needs. The first facility’s mission is to produce 1,000s of
different proteins and their associated molecular affinity tags annually in research quantities
The facility will cost $200M and have a $40M annual operating budget
A proposal call is out with team formation, technical approach, and site selection as objectives
Proposal submission date is April 11, 2006
SNL, LLNL, and LBNL are forming a partnership to develop this facility.
Academic Allies
Other AlliesIndustrial Allies
LLNL
The Bay Area/I-80 Corridor is an outstanding location for this bioscience user facility.
SNL
SNL
11
22
3344
55
6677
88
99
Numbers - biotech centers ranked by sizeNumbers - biotech centers ranked by sizeDOE multiprogram national laboratories
LBNL
Industrial and academic partnering is crucial to the breakthroughs required for all phases of production.
Information/Computing/Process Control
Genes/Clones
Clones/Vectors
Reagents/Tags
Proteins
Sequence
Data
GeneSynthesis
ProteinPurification
ProteinProduction
Affinity ReagentProduction
ProteinCharacterization
Knowledge
Partners and users will benefit from both technology development and products. The facility will provide an anchor for California’s
competitive edge in biotechnology The life sciences community will gain new methods,
new products, and increased knowledge about proteins and related materials
The facility will establish standard protocols for making proteins and affinity reagents
Key additional benefits will include education outreach and entrepreneurial opportunities
We’re here to enlist your help.
Dr. Leonard M. Napolitano, Jr.Sandia National Laboratories, Livermore, CA(925) 294-3218, email: [email protected]
Articulation of the importance of bioscience infrastructure to the state
Identification of leveraging opportunities within the state to increase the economic and technological feasibility of the facility
Contact: