Biosketch TrainingBiosketch Training

Brenda MickleyBrenda Mickley

Business Development AssociateBusiness Development Associate

Lead, Federal ProjectsLead, Federal Projects

DCRIDCRI

March 30, 2009March 30, 2009

ObjectiveObjective

Review the reasons the NIH requires a Review the reasons the NIH requires a biosketchbiosketch

Review each section of a biosketchReview each section of a biosketch

Review why it’s important to understand the Review why it’s important to understand the grants focus when creating a biosketch (i.e.-grants focus when creating a biosketch (i.e.-one biosketch does not fit all)one biosketch does not fit all)

Review differences when we are submitting Review differences when we are submitting the grant electronicallythe grant electronically

Why is a Biosketch ImportantWhy is a Biosketch Important

It conveys to the NIH grant reviewer the It conveys to the NIH grant reviewer the experience that the investigator has in his experience that the investigator has in his professional careerprofessional career EducationEducation Positions heldPositions held Peer-reviewed publicationsPeer-reviewed publications Funded research projects over last three Funded research projects over last three

yearsyears

Biosketch is a mini CVBiosketch is a mini CV

Why is the Biosketch so ImportantWhy is the Biosketch so Important

Recent Reviewers Comments when the biosketch isn’t Recent Reviewers Comments when the biosketch isn’t personalized for the opportunity:personalized for the opportunity:

““Why did this investigator not apply for new investigator Why did this investigator not apply for new investigator on this grant”on this grant” Investigator did not list a current R01 in section CInvestigator did not list a current R01 in section C

““This investigator does not have experience in this area”This investigator does not have experience in this area” Investigator did not include publications in research areaInvestigator did not include publications in research area

““This investigator has not published in the last 2 years”This investigator has not published in the last 2 years” Investigator did not update biosketchInvestigator did not update biosketch

Grants have become more competitive and reviewers are looking closely at the biosketchGrants have become more competitive and

reviewers are looking closely at the biosketch

The BasicsThe Basics NIH Form:

http://grants.nih.gov/grants/funding/phs398/phs398.html

One-half inch margins (top, bottom, left, and right) for all

pages, including continuation pages.

eRA Commons ID

NIH requires the use of one of four approved fonts and a font

size of 11 points or larger. The approved font options include Palatino, Georgia, Arial,

and Helvetica. The Biographical Sketch may not exceed four pages.

Starting the BiosketchStarting the Biosketch

Christopher O’connorChristopher O’connor

OCONN002OCONN002 Professor of Medicine Professor of Medicine

University of Maryland, College Park, MD B.S. 1979 Chemistry

University of Maryland, Baltimore, MD M.D. 1983 Medicine

Duke University, Durham, NC Intern 1984 Medicine

Duke University, Durham, NC Resident 1988 Medicine

Duke University, Durham, NC Fellow 1989 Cardiology

University of Maryland, College Park, MD B.S. 1979 Chemistry

University of Maryland, Baltimore, MD M.D. 1983 Medicine

Duke University, Durham, NC Intern 1984 Medicine

Duke University, Durham, NC Resident 1988 Medicine

Duke University, Durham, NC Fellow 1989 Cardiology

Three Additional SectionsThree Additional Sections

A: Positions and HonorsA: Positions and Honors

B: Selected Peer-reviewed PublicationsB: Selected Peer-reviewed Publications

C: Research SupportC: Research Support

A. Positions and HonorsA. Positions and Honors

List in List in chronological orderchronological order previous previous positions, concluding the investigators positions, concluding the investigators present position. present position.

List any honors. List any honors.

Include present membership on any Include present membership on any Federal Government public advisory Federal Government public advisory committee.committee.

Chronological Order DefinitionChronological Order Definition

:: of, relating to, or arranged in of, relating to, or arranged in or according to the order of or according to the order of timetime

Just be consistent!!Just be consistent!!

19771977 Predoctoral Fellow to Jackson Laboratory, National Institutes of HealthPredoctoral Fellow to Jackson Laboratory, National Institutes of Health

1979 - 19811979 - 1981 Biologist, National Institutes of HealthBiologist, National Institutes of Health

1983 - 19841983 - 1984 Intern in Medicine, Duke University Medical CenterIntern in Medicine, Duke University Medical Center

1984 - 19851984 - 1985 Junior Assistant Resident, Duke University Medical CenterJunior Assistant Resident, Duke University Medical Center

1985 - 19861985 - 1986 Senior Assistant Resident, Duke University Medical CenterSenior Assistant Resident, Duke University Medical Center

1986 - 19871986 - 1987 Assistant Medical Resident, Duke University Medical CenterAssistant Medical Resident, Duke University Medical Center

1987 - 19881987 - 1988 Chief Medical Resident, Durham Veterans Administration HospitalChief Medical Resident, Durham Veterans Administration Hospital

1988 - 19891988 - 1989 Fellow, Duke University Medical CenterFellow, Duke University Medical Center

1989 - 19901989 - 1990 Associate in Medicine, Duke University Medical CenterAssociate in Medicine, Duke University Medical Center

1990 - 19911990 - 1991 Co-Director, Coronary Care Unit, Duke University Medical CenterCo-Director, Coronary Care Unit, Duke University Medical Center

1990 - 1996.1990 - 1996. Assistant Professor of Medicine, Duke University Medical CenterAssistant Professor of Medicine, Duke University Medical Center

1996 - Pres. 1996 - Pres. Associate Professor of MedicineAssociate Professor of Medicine

1991 - 19961991 - 1996 Co-Director, DUCCS Organization, Duke University Medical CenterCo-Director, DUCCS Organization, Duke University Medical Center

1996 - 19971996 - 1997 Executive Director, DUCCS Organization, Duke University Medical CenterExecutive Director, DUCCS Organization, Duke University Medical Center

1997-Present1997-Present Associate Director, Duke Clinical Research InstituteAssociate Director, Duke Clinical Research Institute

1999-Present1999-Present Director, Duke University Cooperative Cardiovascular Studies Organization, Duke UniversityDirector, Duke University Cooperative Cardiovascular Studies Organization, Duke University

2000-Present2000-Present Director, Heart Failure Program, Duke University Medical CenterDirector, Heart Failure Program, Duke University Medical Center

2001-Present2001-Present Chief, Division of Clinical Pharmacology, Duke University Medical CenterChief, Division of Clinical Pharmacology, Duke University Medical Center

2003-Present2003-Present Professor of Medicine, Duke University Medical CenterProfessor of Medicine, Duke University Medical Center

2003-Present2003-Present Associate Professor in Psychiatry and Behavioral SciencesAssociate Professor in Psychiatry and Behavioral Sciences

Professional Experience:Professional Experience:

2007-Present Director, Heart Center 2007-Present Director, Heart Center

Honors (selected):Honors (selected):

American College of Cardiology/Bristol Fellow Achievement AwardAmerican College of Cardiology/Bristol Fellow Achievement Award

American College of Physicians Clinical Vignette Award, Marion Labs, 3/4/88American College of Physicians Clinical Vignette Award, Marion Labs, 3/4/88

Alpha Omega Alpha Medical Honor Society, University of Maryland, 1983Alpha Omega Alpha Medical Honor Society, University of Maryland, 1983

Epidemiology Award, University of Maryland School of Medicine, 1983Epidemiology Award, University of Maryland School of Medicine, 1983

Upjohn Achievement Award (Excellence in Preventive Medicine) Univ. of Maryland Upjohn Achievement Award (Excellence in Preventive Medicine) Univ. of Maryland School of Med. 1983School of Med. 1983

Phi Beta Kappa National Honor Society, University of Maryland, 1979Phi Beta Kappa National Honor Society, University of Maryland, 1979

Goodard Medal (Outstanding Male Graduate UMCP), Univ. of Maryland, College Park, Goodard Medal (Outstanding Male Graduate UMCP), Univ. of Maryland, College Park, 19791979

General Honors Program University of Maryland, College Park, 1979Magna Cum General Honors Program University of Maryland, College Park, 1979Magna Cum Laude, University of Maryland, College Park, 1979Laude, University of Maryland, College Park, 1979

Cum Laude, University of Maryland School of Medicine 1983Cum Laude, University of Maryland School of Medicine 1983

Miller Warner Newcomb Scholarship for Cancer ResearchMiller Warner Newcomb Scholarship for Cancer Research

Any new Honors Any new Honors

Honors (selected): What does this tell us?Honors (selected): What does this tell us?

HonorsHonors

1986-88 Varsity letterman, ACC University, football 1986-88 Varsity letterman, ACC University, football

1986-88 Academic All-Atlantic Coast Conference football team1986-88 Academic All-Atlantic Coast Conference football team

1990 Alpha Epsilon Delta (pre-medical honor society), ACC 1990 Alpha Epsilon Delta (pre-medical honor society), ACC UniversityUniversity

1991 Phi Beta Kappa1991 Phi Beta Kappa

1991 Magna cum laude, ACC University 1991 Magna cum laude, ACC University

1992 Senior Scholarship recipient, Duke University School of 1992 Senior Scholarship recipient, Duke University School of MedicineMedicine

1995 Alpha Omega Alpha1995 Alpha Omega Alpha

1998 Drug Company award for excellence in basic scientific 1998 Drug Company award for excellence in basic scientific researchresearch

B: Selected peer-reviewed publicationsB: Selected peer-reviewed publications

Selected peer-reviewed publications or manuscripts Selected peer-reviewed publications or manuscripts in press (in press (in chronological orderin chronological order). ).

Do not include manuscripts submitted or in Do not include manuscripts submitted or in preparation. preparation.

For publicly available citations, URLs or PMC For publicly available citations, URLs or PMC submission identification numbers should submission identification numbers should accompany the full reference. accompany the full reference.

Copies of publicly available publications are not Copies of publicly available publications are not accepted as appendix material.accepted as appendix material.

PebMed Central ID (PMCID)-NOT PMIDPebMed Central ID (PMCID)-NOT PMID

The National Institutes of Health (NIH) Public Access Policy The National Institutes of Health (NIH) Public Access Policy became effective April 7, 2008. became effective April 7, 2008.

Under federal law, NIH now requires that the author’s final Under federal law, NIH now requires that the author’s final version of version of any peer-reviewed journal articleany peer-reviewed journal article resulting from resulting from NIH-funded activitiesNIH-funded activities must be submitted to the PubMed Central must be submitted to the PubMed Central (PMC) repository(PMC) repository

The publication will be made available to the public within 12 The publication will be made available to the public within 12 months after the journal article is published. months after the journal article is published.

This new policy has several compliance issues that Duke This new policy has several compliance issues that Duke authors need to address. authors need to address.

Update (March 12, 2009): President Obama has signed into law Update (March 12, 2009): President Obama has signed into law the 2009 Consolidated Appropriations Act, which includes a the 2009 Consolidated Appropriations Act, which includes a provision making the NIH Public Access Policy permanent.provision making the NIH Public Access Policy permanent.

Pub Med Central (PMC) Helpful LinksPub Med Central (PMC) Helpful Links

Pubmed Central: Pubmed Central: http://http://www.pubmedcentral.nih.govwww.pubmedcentral.nih.gov//

NIH Public Access Policy FAQ: NIH Public Access Policy FAQ: http://http://publicaccess.nih.gov/FAQ.htmpublicaccess.nih.gov/FAQ.htm

Journals that systematically submit articles to PubMed Journals that systematically submit articles to PubMed Central: Central: http://http://publicaccess.nih.gov/submit_process_journals.htmpublicaccess.nih.gov/submit_process_journals.htm

Tutorial on the NIHMS System: Tutorial on the NIHMS System: http://www.nihms.nih.gov/web-help/index.htmlhttp://www.nihms.nih.gov/web-help/index.html

Information and services provided by Duke Medical Information and services provided by Duke Medical Center Library: Center Library: http://http://www.mclibrary.duke.edu/nihpolicywww.mclibrary.duke.edu/nihpolicy

ExampleExample

Podgoreanu MV, White WD, Morris RW, Matthew JP, Stafford-Podgoreanu MV, White WD, Morris RW, Matthew JP, Stafford-Smith M, Welsby IJ, Grocott HP, Milano CA, Newman MF, Smith M, Welsby IJ, Grocott HP, Milano CA, Newman MF, Schwinn DA. “Inflammatory Gene Polymorphisms and Risk of Schwinn DA. “Inflammatory Gene Polymorphisms and Risk of Postoperative Myocardial Infarction after Cardiac Surgery”. Postoperative Myocardial Infarction after Cardiac Surgery”. Circulation 2006;114 (suppl I): I-275-I-281. Circulation 2006;114 (suppl I): I-275-I-281. PMC1945056PMC1945056

B: Selected peer-reviewed publicationsB: Selected peer-reviewed publicationsWhat does the Publications tell you about the investigators career?What does the Publications tell you about the investigators career?

Hlatky MA, Cotugno H, Hlatky MA, Cotugno H, O'Connor C, Mark DB, Pryor DB, Califf RM. Adoption of Mark DB, Pryor DB, Califf RM. Adoption of thrombolytic therapy in the management of acute myocardial infarction. thrombolytic therapy in the management of acute myocardial infarction. Am J CardiolAm J Cardiol 1988;61(8):510-4. 1988;61(8):510-4.

O'Connor CMO'Connor CM,, Califf RM, Massey EW, Mark DB, Kereiakes DJ, Candela RJ, Califf RM, Massey EW, Mark DB, Kereiakes DJ, Candela RJ, Abbottsmith C, George B, Stack RS, Aronson L, et al. Stroke and acute myocardial Abbottsmith C, George B, Stack RS, Aronson L, et al. Stroke and acute myocardial infarction in the thrombolytic era: clinical correlates and long-term prognosis. infarction in the thrombolytic era: clinical correlates and long-term prognosis. J Am J Am Coll CardiolColl Cardiol 1990;16(3):533-40. 1990;16(3):533-40.

Whellan DJ, Shaw LK, Bart BA, Kraus WE, Califf RM, Whellan DJ, Shaw LK, Bart BA, Kraus WE, Califf RM, O'Connor CM.O'Connor CM. Cardiac Cardiac rehabilitation and survival in patients with left ventricular systolic dysfunction. rehabilitation and survival in patients with left ventricular systolic dysfunction. Am Am Heart JHeart J 2001; 2001;142142(1)(1)::160-6.160-6.

Third Author: part of research teamThird Author: part of research team

First Author, his research project, counts towards tenure

First Author, his research project, counts towards tenure

Senior Author, mentored first author, counts towards tenure

Senior Author, mentored first author, counts towards tenure

QUESTION?? QUESTION??

What do you do when you have What do you do when you have over 166 publications and over 166 publications and

only have 2 pages worth of only have 2 pages worth of space?space?

B: Selected peer-reviewed publicationsB: Selected peer-reviewed publications

Grant focusGrant focus

Authorship position Authorship position

NIH funded manuscript NIH funded manuscript

Journal “impact rating”Journal “impact rating”

B: Selected peer-reviewed publicationsB: Selected peer-reviewed publications

Grant focus: Heart Failure Grant focus: Heart Failure 74 Publications74 Publications

AuthorshipAuthorship First Author: 19First Author: 19 Senior Author: 35Senior Author: 35

NIH Funded PublicationNIH Funded Publication 4343

Journal “Impact Factor”Journal “Impact Factor”

Copyright restrictions may apply.

Garfield, E. JAMA 2006;295:90-93.

Selected Biomedical Journals Ranked by Impact Factor

B: Selected peer-reviewed publicationsB: Selected peer-reviewed publications

Journal “Impact Factor”Journal “Impact Factor” JAMA-5 publicationsJAMA-5 publications

– O’Connor is first author on two

Lancet-1 publicationLancet-1 publication– O’Connor is senior author

Ann Intern Med-1 publicationAnn Intern Med-1 publication Arch Intern Med-8 publicationsArch Intern Med-8 publications

– O’Connor is senior author on five

Research SupportResearch Support List both selected ongoing and completed

research projects

Past three years (Federal or non-Federally-

supported). Begin with the projects that are most relevant to

the research proposed in the application.

Briefly indicate the overall goals of the projects and responsibilities of the key person identified on the Biographical Sketch.

Do not include number of person months or direct costs.

Research SupportResearch Support

5U01-HL063747-05 O’Connor (PI) 9/30/02 – 6/30/2009

NHLBI

ACTION: A CHF Trial Investigating Outcomes of Exercise Training

The DCRI is the Coordinating center for this multi-center randomized trial whose goal is to assess if exercise training improves clinical outcomes for heart failure.

Role: PI

Research SupportResearch Support

Do not confuse "Research Support" with "Other Support."

"Research Support" highlights the investigators accomplishments

This information will be used by the reviewers in the assessment of each individual's qualifications for a specific role in the proposed project, as well as to evaluate the overall qualifications of the research team.

"Other Support" information is required for all applications that are selected to receive grant awards and includes detailed financial information

Why a biosketch isn’t a “one size fits all”Why a biosketch isn’t a “one size fits all”

Type of grant: research grant vs. a Type of grant: research grant vs. a mentoring grantmentoring grant

Grant FocusGrant Focus

Role on Grant Role on Grant

NIH Biosketch for Electronic SubmissionNIH Biosketch for Electronic Submission

Just delete the header and Just delete the header and footer!!footer!!

QUESTIONS???QUESTIONS???