ALSPAC clinics
Larisa Duffy – Clinic [email protected]
The beginning
About 14, 500 pregnant womenAbout 12,000 new born babies were measured
Children in Focus (CiF)
Clinic Attendance
Young People @17
Observations
• Blood – Glucose, haemoglobin,lipids & cotinine
samples– DNA samples
• Urine and Hair– Chlamydia/gonorrhoea tests on behalf of the
National Chlamydia Screening Programme
• Blood pressure and pulse rate
Anthropometry
• height, weight, body fat, scoliosis • a whole body scan and a hip DXA scan• A pQCT scan of the lower leg
Computerised questionnaire• mental health (depression)• substance use (tobacco, alcohol & drugs)• Gambling • DCSF
Interviews• PLIKS and CSQ• N Back, Probability and Go No-Go
Questionnaires
• on chronic pain, life events and fractures • dental health questionnaire to take home and
send back by post in ALSPAC packaging• girls are given a questionnaire about their
cycle, the date of the first day of their last period and contraception.
Scans
• carotid artery in the neck• liver• heart
Monitors• activity monitor (G-Force)• blood pressure
Clinic ChartYP 1 YP 2 YP 3 YP 4 YP 5 YP 6 YP 7 YP 8
8:20 Blood Blood Blood
8:40 Blood Blood Blood
9:00 Artery Com Q Intview Blood Blood
9:20 DXA BP Com Q Hair
9:40 DXA Intview BP Com Q Hair Com Q Com Q Artery
10:00 Intview Com Q Hair Com Q Artery DXA
10:20 BP Hair Com Q Artery Intview DXA
10:40 BP Hair Com Q Artery DXA Intview
11:00 Com Q Com Q Artery DXA Intview BP
11:20 Hair Artery DXA Intview Com Q BP
11:40 Com Q DXA Intview BP Hair Com Q
12:00 BP Com Q Artery Hair
12:20 Com Q
Mothers’ Observations
– DXA scan for fat & lean mass and bone density– Carotid intima media thickness– Blood pressure– Height, weight, waist, hip and head circumference– Fasting blood samples (funds to complete assays on
fasting glucose, insulin, pro-insulin, lipids and to store serum)
Mothers’ clinic chart
FW1 FW2 FW3 FW4 FW1 FW2 FW3 FW4
08:000 Blood Blood
08:200 Blood
08:400 DXA A1 Blood
09:000 A1 DXA A2
09:250 DXA A2 Blood Blood
09:500 DXA Blood
10:100 DXA A1 Blood
10:300 A1 DXA A2
10:550 DXA A2
11:200 DXA
Fathers’ Clinic
• Fasting Blood sample• Height, weight, waist and hip circumference• Blood pressure• DXA scan• Life style questionnaires