Transcript
Page 1: Antibodies Newsflash - February 2014 - BBI Solutions

Newsflash February 2014

New Data Available

Dengue NS1

Malaria

Capabilities

Monoclonal Antibodies

Polyclonal Antibodies

Recombinant Fab Antibodies

Quality InnovationResultsPartnership

Page 2: Antibodies Newsflash - February 2014 - BBI Solutions

Be confident in your results when you

choose BBI’s monoclonal antibodies for

your next assay:

Tested in ELISA

Tested in Lateral Flow

Recommended pairings provided

Strong Customer Feedback

We have now introduced highly sensitive

Recombinant Fab antibodies to improve

your next generation assays

Custom development and manufacturing

services to meet your individual

requirements

Why choose BBI ?

Quick Links

Dengue NS1 Antibodies >

Malaria Antibodies >

Monoclonal Antibodies >

Polyclonal Antibodies >

Recombinant Fab

Antibodies >

How to Order >

Page 3: Antibodies Newsflash - February 2014 - BBI Solutions

Antibody Spotlight

NEW DATA – Dengue NS1 Antibodies

We have developed panels of antibodies for detecting the four different Dengue

subtypes. Our Dengue Antibodies can detect the presence of Dengue antigens

down to 0.5ng/ml or lower. The antibodies have been tested in patient samples.

Dengue Subtype 1

Detection of 0.5ng/ml antigen

concentration can be obtained with

our recommended pairings.

Recommended Sandwich Pairings

Capture Antibody Detection Antibody

BM404-K2G4 BM409-V8F1

BM404-K2G4 BM409-G3D1

BM409-P3B4 BM409-P3B4

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Dengue NS1 Subtype 1 Antigen Concentration (ng/ml)

Lateral Flow using BM404-K2G4 as Capture Antibody

BM409-V8F1

BM409-G3D1

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Page 4: Antibodies Newsflash - February 2014 - BBI Solutions

Antibody Spotlight

NEW DATA – Dengue NS1 Antibodies

Dengue Subtype 2

We recommend these pairings for

Dengue Subtype 2 Antibodies for

use in Lateral Flow.

Recommended Sandwich Pairings

Capture Antibody Detection Antibody

BM339-T3H2 BM339-P3D8

BM339-T3H2 BM339-P6D8

Dengue Subtype 3

Recommended Sandwich Pairings

Capture Antibody Detection Antibody

BM405-K9A5 BM406-F2E8

BM406-F2E8 BM405-K9A5

Detection of 0.5ng/ml antigen

concentration can be obtained with

our recommended pairings. 0

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Dengue NS1 Subtype 3 Antigen Concentration (mg/ml)

Dengue Substype 3 Antibodies tested in Lateral Flow

BM405-K9A5 (D), BM406-F3E8 (C)

BM406-F3E8 (D), BM406-K9A5 (C)

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Page 5: Antibodies Newsflash - February 2014 - BBI Solutions

Antibody Spotlight

NEW DATA – Dengue NS1 Antibodies

Dengue Subtype 4

Recommended Sandwich Pairings

Capture Antibody Detection Antibody

BM408-N9G5 BM407-K3A2

BM408-N9G5 BM408-G8E7

BM408-N9G5 BM408-M2B3

BM408-N9G5 BM408-F5F4

BM408-N9G5 BM408-E1D5

Detection of 0.5ng/ml antigen

concentration can be obtained with

our recommended pairings.

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Dengue NS1 Antigen Subtype 4 Concentration (ng/mg)

Lateral Flow using BM408-N9G5 as Capture

BM407-K3A2

BM408-G8E7

BM408-M2B3

BM408-F5F4

BM408-E1D5

Detection Antibodies

Order your evaluation samples today:

[email protected] | USA: 1-800-423-8199 | Intl: +44 (0) 2920 747 232

Return home >

Page 6: Antibodies Newsflash - February 2014 - BBI Solutions

Antibody Spotlight

NEW DATA – Malaria Antibodies

Our antibodies can detect the presence of Malaria antigen down to 0.5ng/ml or

lower. All of our Malaria antibodies have been tested in Lateral Flow using patient

samples.

Malaria HRP 2

Recommended Sandwich Pairings

Capture Antibody Detection Antibody

BM340-F5D2 BM340-F5D2

BM340-F5D2 BM340-Z2D5

BM340-F5D2 BM340-U7D4

BM340-F5D2 BM340-S1F4

Detection of 0.5ng/ml antigen

concentration can be obtained with

our recommended pairings.

Detection

Antibodies

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Malaria HRP2 Concentration (mg/ml)

Lateral Flow using BM340-F5D2 as Capture

Z2D5

F5D2

U7D4

S1F4

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Page 7: Antibodies Newsflash - February 2014 - BBI Solutions

Antibody Spotlight

NEW DATA – Malaria Antibodies

Malaria LDH pan (detects all Plasmodium species)

Recommended Sandwich Pairings

Capture Antibody Detection Antibody

BM355-P2H3 or BM355-P4A2 BM355-P4A2

BM355-P2G3 or BM355-P4A2 BM244-Z8F7

Detection of 0.5ng/ml

antigen concentration can

be obtained with our

recommended pairings.

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pLDH Malaria Antigen Concentration (ng/mg)

Lateral Flow for LDH (pan) Malaria Antibodies

BM355-P4A2 (D), BM355-P2H3 (C)

MB355-P4A2 (D), BM355-P4A2 (C)

BM244-Z8F7 (D), BM355-P2H3 (C)

BM244-Z8F7 (D), BM355-P4A2 (C)

We also have a panel of P.

falciparum – specific LDH

antibodies available.

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Page 8: Antibodies Newsflash - February 2014 - BBI Solutions

Our Capabilities | Monoclonal Antibodies

Cardiac Infectious Disease Norovirus

CK-MB C. difficile Toxin A PBP2a

D-Dimer C. difficile Toxin B TB

Myoglobin Chikungunya

Troponin I Dengue NS1 Pregnancy

H. pylori AFP

Diabetes HAV

Hb HBV Tumour

HbA1c Hepatitis B CA125

HIV p24 CA15-3

Drugs of abuse HIV gp35 CA19-9

THCΔ9 HIV gp41 Calcitonin

Influenza A

Hormones Influenza B Immunoglobulins

DHEA-S Leptospira IgA

Cortisol Listeria IgE

Progesterone Malaria HRP2 IgG

PTH Malaria LHD (pan) IgM

Malaria LHD (Pf)

Malaria LDH (Pf & Pv) Return home >

Page 9: Antibodies Newsflash - February 2014 - BBI Solutions

Our Capabilities | Polyclonal Antibodies

Inflammation Pregnancy Renal

CRP AFP A2M

B2M

Hormones Inflammatory Cystatin C

HCG A1AT

αHCG

Haematology Metabolism

Immunoglobulins Haptoglobin Ceruloplasmin

IgA Ferritin

IgM Haemoglobin

IgG

Albumin

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Page 10: Antibodies Newsflash - February 2014 - BBI Solutions

Our Capabilities | Recombinant Fab Antibodies

* Detection Ranges are assay dependent and optimised for specific

clinical conditions, therefore may be improved with optimisation Return home >

Biomarker Detection Range* Capture Antibody Detection Antibody

HSP60 0.1 - 1200 ng/mL BR100-G2A7 BR100-H4C2

Adiponectin 0.1 - 525 ng/mL BR101-P7E2 BR101-M3H8

Adiponectin 230 - 59118 ng/mL BR101-H2B4 (Competitive ELISA)

Angiopoietin 2 0.001 - 97 ng/mL BR103-P4E8 BR103-V5F2

Big Endothelin 1 0.001 - 1.8 ng/mL BR104-D6A4 BR104-H1A4

Calcitonin 0.006 - 2 ng/mL BR388-G6B1 BR388-D5C4

Cathepsin D 0.03 - 150 ng/mL BR107-F5G2 BR107-K6D3

Eotaxin 0.007 - 2 ng/mL BR108-M7H3 BR108-K2D9

Chondrolectin 0.9 - 21 ng/mL BR111-P8G3 BR111-T6B1

CKBB 0.15 - 33 ng/mL BR112-V6F6 BR112-Z1C4

Proinsulin C-Peptide 0.09 - 38 ng/mL BR143-G5D3 BR143-K7C9

CRP 151 - 231000 ng/mL BR228-D4A3 (Competitive ELISA)

Cystatin C 165 - 9073 ng/mL BR175-G8D9 (Competitive ELISA)

Cystatin C 165 - 9073 ng/mL BR175-H4C8 (Competitive ELISA)

E. histolytica not tested BR116-K9F7 BR116-G3A1

E-selectin 0.05 - 235 ng/mL BR117-K2E7 BR117-H5B6

FABP Intestine 0.65 - 100 ng/mL BR115-F7G7 BR115-G6B9

FABP Liver 0.03 - 90 ng/mL BR106-G5A2 BR106-P9F5

Page 11: Antibodies Newsflash - February 2014 - BBI Solutions

Our Capabilities | Recombinant Fab Antibodies

* Detection Ranges are assay dependent and optimised for specific

clinical conditions, therefore may be improved with optimisation Return home >

Biomarker Detection Range* Capture Antibody Detection Antibody

G. lamblia not tested BR120-P3F2 & BR120-T1G8

Human Fetal Hemoglobin 1.9 - 305 ng/mL BR121-T5H9 BR121-V5A7

Leptin 3.9 - 691 ng/mL BR123-M4D6 BR123-P4G2

MMP7 0.1 - 293 ng/mL BR124-S4E3 BR124-T6G8

MMP9 Active 11 - 183 ng/mL BR125-N5F7 BR125-M6D6

MPO 2 - 1200 ng/mL BR240-N5G6 BR240-D8B4

Neutrophil Elastase 0.008 - 33 ng/mL BR127-H2A4 BR127-G7C2

Free PAPP A 0.3 - 299 ng/mL BR129-M5E3 BR129-F2H4

Pentraxin 3 4.6 - 876 ng/mL BR130-H2C3 BR130-K6D6

PGDS 0.2 - 85 ng/mL BR131-M6H7 BR131-P7F7

PSAP A 0.013 - 123 ng/mL BR132-T5G4 BR132-S6E4

PSAP B 0.3 - 1500 ng/mL BR133-V6B5 BR133-V4D1

RBP 4 350 - 500000 ng/mL BR134-Z7D3 (Competitive ELISA)

S100 Beta 0.04 - 5.6 ng/mL BR332-G4B9 BR332-F5H7

ST2 1.39 - 97 ng/mL BR139-S7B7 BR139-V8D4

ST2 0.08 - 31 ng/mL BR139-T3G5 BR139-V8D4

Tie2 0.8 - 600 ng/mL BR140-Z7A5 BR140-D9D7

Page 12: Antibodies Newsflash - February 2014 - BBI Solutions

How to Order

Please get in touch to arrange a quote for

any of our products.

[email protected]

USA: 1-800-423-8199

Intl: +44 (0) 2920 747 232

Quote on ordering – NF FEB

BBI Solutions

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