Download - Bio Sodium h Yalu Ron Ate
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Bio Sodium Hyaluronate 1
Bio-
Sodium
Hyaluronate
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Bio Sodium Hyaluronate 2
Hyaluronic Acid
# Natural polymer found in nature, particularly in skin
and connective tissues of human and animal.
# Linear polysaccharide built from regularly alternating
units of glucuronic acid and N-acetylglucosamine
(102 to 104 units).
# Molecular weight range from ten thousand to several
Million Daltons.
# The most hydrated biopolymer known.
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Bio Sodium Hyaluronate 3
Functions of Hyaluronic Acid
# The amount of hyaluronic acid, water content, and
elasticity of the skin related to aging.
# Hyaluronic acid forms a viscoelastic, colorless,
transparent and non-occlusive film on skin
-> Moisturizing, increasing elasticity
# Works as a lubricant and shock-absorbing agent for joints.
# Protects body from external infections
# Promotes wound healing.
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Bio Sodium Hyaluronate 4
Cosmetic Applications of HA
# Skin care (Particularly treatment of dry skin)
# Eye contour cream/gel
# Liposome gel
#After-sun lotion
# Body lotion
# Decorative cosmetic, specially for hair care products
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Bio Sodium Hyaluronate 5
Bio Sodium Hyaluronate
# Produced by biotechnology.
# Free of contamination and proteins of animal origin.
# High purity and quality.
# Various molecular weights.
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Bio Sodium Hyaluronate 6
Chemical Structure
OO a
n
A sodium salt of mucopolysaccharide having a straight
chain structure made of repetitious disaccharide units of
Gluccuronic acid and N-Acetylglucosamine.
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Bio Sodium Hyaluronate 7
Bio Sodium Hyaluronate
# Bio Sodium Hyaluronate MMW
# Bio Sodium Hyaluronate LMW
# Bio Sodium Hyaluronate HMW
# Nutra HA
# Standardized Solution (0.5%, 1%)
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Bio Sodium Hyaluronate 8
SPECIFICATIONPRODUCT NAME : Bio Sodium Hyaluronate MMW
White Powder
Colorless, clear and viscous liquid
5.0 ~ 8.0
Max. 20 ppm
Max. 2 ppmMax. 10.0%
45.0 ~ 48.4%
93.0 ~ 100.0%
Max. 0.1%
Max. 10.0%Not Detected
1.3 ~ 1.8 Mda
Less than 1 x 102
cfu/g
Not Detected
Description
Appearance of 0.5% Soln.
pH(0.5%)
Heavy Metals
ArsenicWater Content (KF)
Uronic Acid Content
Sodium Hyaluronate
Protein Content
Residue on IgnitionOther Acidic Mucopolysaccharides
Molecular Weight (GPC)
Total Plate Count
Hemolytic Streptococci
SpecificationsAnalytical Tests
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Bio Sodium Hyaluronate 9
SPECIFICATIONPRODUCT NAME : Bio Sodium Hyaluronate LMW
White Powder
Colorless, clear and viscous liquid
5.0 ~ 8.0
Max. 20 ppm
Max. 2 ppmMax. 10.0%
45.0 ~ 48.4%
93.0 ~ 100.0%
Max. 0.1%
Max. 10.0%Not Detected
0.5 ~ 1.3 Mda
Less than 1 x 102
cfu/g
Not Detected
Description
Appearance of 0.5% Soln.
pH(0.5%)
Heavy Metals
ArsenicWater Content (KF)
Uronic Acid Content
Sodium Hyaluronate
Protein Content
Residue on IgnitionOther Acidic Mucopolysaccharides
Molecular Weight (GPC)
Total Plate Count
Hemolytic Streptococci
SpecificationsAnalytical Tests
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Bio Sodium Hyaluronate 10
SPECIFICATIONPRODUCT NAME : Bio Sodium Hyaluronate HMW
White Powder
Colorless, clear and viscous liquid
5.0 ~ 8.0
Max. 20 ppm
Max. 2 ppmMax. 10.0%
45.0 ~ 48.4%
93.0 ~ 100.0%
Max. 0.1%
Max. 10.0%
Not Detected
1.8 ~ 2.5 Mda
Less than 1 x 102
cfu/g
Not Detected
Description
Appearance of 0.5% Soln.
pH(0.5%)
Heavy Metals
ArsenicWater Content (KF)
Uronic Acid Content
Sodium Hyaluronate
Protein Content
Residue on Ignition
Other Acidic Mucopolysaccharides
Molecular Weight (GPC)
Total Plate Count
Hemolytic Streptococci
SpecificationsAnalytical Tests
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Bio Sodium Hyaluronate 11
SPECIFICATIONPRODUCT NAME : Nutra HA
White Powder
Colorless, clear and viscous liquid
5.0 ~ 8.0
Max. 20 ppm
Max. 2 ppm
Max. 10.0%
45.0 ~ 48.4%
93.0 ~ 100.0%
Max. 0.1%
Max. 10.0%
Not Detected
0.5 ~ 1.1 MdaLess than 1 x 10
2cfu/g
Not Detected
Not Detected
Not Detected
Description
Appearance of 0.5% Soln.
pH(0.5%)
Heavy Metals
Arsenic
Water Content (KF)
Uronic Acid Content
Sodium Hyaluronate
Protein Content
Residue on Ignition
Other Acidic Mucopolysaccharides
Molecular Weight (GPC)Total Plate Count
Hemolytic Streptococci
Coli Form
Salmonella
SpecificationsAnalytical Tests
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Bio Sodium Hyaluronate 12
SPECIFICATIONPRODUCT NAME : Bio Sodium Hyaluronate 1% Soln.
Colorless, clear and viscous liquid
5.0 ~ 8.0
Max. 20 ppm
Max. 2 ppm
Min. 1.0%Max. 0.001%
Not Detected
Min. 10,000cps
Min. 1.0MdaLess than 1 x 10
2cfu/g
Not Detected
Description
pH
Heavy Metals
Arsenic
Sodium HyaluronateProtein Content
Other Acidic Mucopolysaccharides
Viscosity (Brookfield
DVII+, 25, 12rpm, Spin 4)
Molecular Weight (GPC)Total Plate Count
Hemolytic Streptococci
SpecificationsAnalytical Tests
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Bio Sodium Hyaluronate 13
SPECIFICATIONPRODUCT NAME : Bio Sodium Hyaluronate 0.5% Soln.
Colorless, clear and viscous liquid
5.0 ~ 7.0
Max. 20 ppm
Max. 2 ppm
0.45 ~ 0.55%
Max. 0.01%
Not Detected
1,000 ~ 2,000cps
Less than 1 x 102 cfu/g
Not Detected
Description
pH
Heavy Metals
Arsenic
Sodium Hyaluronate
Protein Content
Other Acidic Mucopolysaccharides
Viscosity (Brookfield
DVII+, 25, 12rpm, Spin 4)
Total Plate Count
Hemolytic Streptococci
SpecificationsAnalytical Tests
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Bio Sodium Hyaluronate 14
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