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BioPathwise 2.0BioPathwise 2.0A System for Pathway-Centric
Collaborative Research
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2001-2006 The BioAnalytics Group LLC. All Rights Reserved
OutlineOutline
The BioAnalytics Group
The Problem and Potential of Collaboration
BioPathwise 2.0
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2001-2006 The BioAnalytics Group LLC. All Rights Reserved
The BioAnalytics GroupThe BioAnalytics Group
Offers software-based products and services to biomedical researchers.
Services include custom software development, modeling research, data analysis, and training.
Products include image analysis, optimization and pathway analysis software.
A participant in the Program for Immune Modeling & Experimentation (PRIME), funded by the NIAID.
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2001-2006 The BioAnalytics Group LLC. All Rights Reserved
Multidisciplinary CollaborationMultidisciplinary Collaboration
Biological Researchers
Computational Biologists
Bioinformaticians
How do I communicate my results to other researchers and make use of their hard work in my research?
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2001-2006 The BioAnalytics Group LLC. All Rights Reserved
BioPathwise 2.0BioPathwise 2.0
A computer-based solution designed to organize, view, analyze and share data and knowledge in the form of pathways.
Building & Viewing
Pathways
Simulation, Data Analysis &
Visualization
Data & Pathway Repository
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2001-2006 The BioAnalytics Group LLC. All Rights Reserved
Building Pathways with Building Pathways with BioPathwiseBioPathwise
Import pathways
Pathways constructed by querying Reaction Database
Constructing networks from data
Enhancing existing pathways with your knowledge
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2001-2006 The BioAnalytics Group LLC. All Rights Reserved
The BioPathwise RepositoryThe BioPathwise Repository
Searchable Collection of Pathways
Molecule PagesDynamically formatted Reports
The Rest of Biology
Access to Current Literature
Reaction Database
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2001-2006 The BioAnalytics Group LLC. All Rights Reserved
Annotating PathwaysAnnotating Pathways
Text
Structured Annotations
Attached Documents, Images, and Data
Hyperlinks to any web resource
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2001-2006 The BioAnalytics Group LLC. All Rights Reserved
Pathway-CentricPathway-CentricData VisualizationData Visualization
Importing Data
Visualization of Categorical and Time Series Data
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2001-2006 The BioAnalytics Group LLC. All Rights Reserved
Pre-kinetic Pathway AnalysisPre-kinetic Pathway Analysis
Network analysis to highlightCritical points
Complementary Paths
Shortest Paths
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2001-2006 The BioAnalytics Group LLC. All Rights Reserved
SimulationSimulation
Hypothesis testing
Experimental Design and Automation
Parameter Estimation and Sensitivity
Pathway-Centric Visualization
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2001-2006 The BioAnalytics Group LLC. All Rights Reserved
CollaborationCollaboration
Share Models using the Repository
Export Models to Third-Party Formats
Publish Models to the Web
Export Publication Quality Graphics
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2001-2006 The BioAnalytics Group LLC. All Rights Reserved
BioPathwise BioPathwise Programming InterfaceProgramming Interface
Interfacing with 3rd party products
Algorithm Developers
Application Developers
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2001-2006 The BioAnalytics Group LLC. All Rights Reserved
Availability and PricingAvailability and Pricing
BioPathwise 2.0 Available Mid-July ’06
Pricing:Desktop Application
$3000 commercial
$600 academic
$300 per class for classroom use
Server (includes 5 desktop licenses)Prices start at $25k commercial
Includes hardware, configuration, training
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2001-2006 The BioAnalytics Group LLC. All Rights Reserved
AcknowledgmentsAcknowledgments
Physiome Sciences Team (PathwayPrism v. 3.0)Kam-Chuen Jim, Guanming Wu, Jinpeng Xing, Yi Ge, Jonathan M. Shuali, Haoyu Yu, Robert Tjon, Zhuang Zuo, Jose Fernandez, Ninu Mehta, Stephen Lin, Andrew LeBeau, Fred Livingston, Jian Wang, Ned Haubein, Scott Lett, Haoyu Yu, Guanming Wu, Abram Goykhman, Brett Bu Sha, Katarzyna Stanczewska
BioAnalytics Team (BioPathwise v. 1.0, 2.0)Ned Haubein, Rashmi Gupta, Steven Alfisi
PRIME Team (Hours of use, plenty of feedback)Mount Sinai School of Medicine
Ohio State
Princeton University
NIAID