Download - Blood transfusions
Blood transfusions
• If blood types are not properly matched clumping (agglutination) of the red blood cells can occur.
• Red blood cells have agglutinins on their surface (a type of antigen).
• You blood plasma has antibodies which can react against the agglutinins on your red blood cells
Clotting
• When platelets in blood are exposed to air chemical reaction occurs.
• A soluble protein in your plasma changes to an insoluble fibrin – a scab.
• Vitamin K is important to clotting- made by bacteria in the gut or ingested by eating green veg and cranberries.
Abnormal clotting
• Haemophilia – slow clotting.
• High cholesterol and smoking and drinking alcohol increase your chances of clotting
• Warfarin, aspirin and heparin reduce the bloods ability to clot.
Blood Groups
Rhesus positive and negative
• Rhesus positive if your plasma has a D – protein.
• Blood that is Rh-negative can be transfused into a person who is Rh-positive, but an Rh-negative individual can create antibodies for Rh-positive.
Universal Recipient
• AB+ blood type is referred to as the "universal recipient",
• Anti-B or Anti-A antibodies in its plasma, and can receive both Rh-positive and Rh-negative blood
Universal Donor
• O- blood type is called the ‘’universal donor’’
• It’s red blood cells have no A or B antigens and are Rh-negative, no other blood type will reject it.
Long Leave Prep
• Draw a timeline for the discovery and development of blood transfusions.
• I will take posters in beginning of next term. A4 or A3.
• Go over everything we have done so far – answer the questions in the book if haven’t already!