BookSections(revised1/7/18)
Chem4511&Chem6501
LehningerPrinciplesofBiochemistry,7thEditionProfessorsHudandWilliams
1.TheFoundationsofBiochemistry (40pages,1-40)1.1CellularFoundations1.2ChemicalFoundations1.3PhysicalFoundations1.4GeneticFoundations2.Water(23pages,47-69)2.1WeakInteractionsinAqueousSystems(47-58)2.2IonizationofWater,WeakAcids,andWeakBases(58-63)2.3BufferingagainstpHChangesinBiologicalSystems(63-69)2.4WaterasaReactant(69)2.5TheFitnessofAqueousEnvironmentforLivingOrganisms(69)3.AminoAcids,Peptides,andProteins(35pages,75-109)3.1AminoAcids(75-85)3.2PeptidesandProteins(85-89)3.3WorkingwithProteins(89-96)3.4TheStructureofProteins:PrimaryStructure(96-109)(Useofproteinsequencestoconstructevolutionarytrees).4.TheThree-DimensionalStructureofProteins(37pages,115-151)4.1OverviewofProteinStructure(115-119)4.2ProteinSecondaryStructure(119-125)4.3ProteinTertiaryandQuaternaryStructures(125-142)4.4ProteinDenaturationandFolding(142-151)5.ProteinFunction(27pages,157-183)5.1ReversibleBindingofaProteintoaLigand:Oxygen-BindingProteins(157-174)5.2ComplementaryInteractionsbetweenProteinsandLigands:TheImmuneSystemandImmunoglobulins(174-179)5.3ProteinInteractionsModulatedbyChemicalEnergy:Actin,Myosin,andMolecularMotors(179-183)6.Enzymes(50pages,187-236;27pages187-213)6.1AnIntroductiontoEnzymes(187-189)6.2HowEnzymesWork(190-198)6.3EnzymeKineticsasanApproachtoUnderstandingMechanism(198-213)7.CarbohydratesandGlycobiology(35pages,241-275)7.1MonosaccharidesandDisaccharides(241-252)7.2Polysaccharides(252-261)7.3Glycoconjugates:Proteoglycans,Glycoproteins,andGlycolipids(261-267)
7.4CarbohydratesasInformationalMolecules:TheSugarCode(267-272)7.5WorkingwithCarbohydrates(272-275)8.NucleotidesandNucleicAcids(35pages,279-313)8.1SomeBasics(279-285)8.2NucleicAcidStructure(285-295)8.3NucleicAcidChemistry(295-310)8.4OtherFunctionsofNucleotides(310-313)9.DNA-BasedInformationTechnologies(37pages,319-355)9.1StudyingGenesandTheirProducts(319-335)9.2UsingDNA-BasedMethodstoUnderstandProteinFunction(335-344)9.3GenomicsandtheHumanStory(334-355)10.Lipids(24,pages,361-384)10.1StorageLipids(361-366)10.2StructuralLipidsinMembranes(366-374)10.3LipidsasSignals,Cofactors,andPigments(374-381)10.4WorkingwithLipids(381-384)24.GenesandChromosomes(25pages,957-981)24.1ChromosomalElements(957-963)24.2DNASupercoiling(963-972)24.3TheStructureofChromosomes(972-981)25.DNAMetabolism(43pages,989-1031)25.1DNAReplication(989-1005)25.2DNARepair(1005-1016)25.3DNARecombination(1016-1031)26.RNAMetabolism(40pages,1035-1074)26.1DNA-DependentSynthesisofRNA(1036-1047)26.2RNAProcessing(1047-1063)26.3RNA-DependentSynthesisofRNAandDNA(1063-1074)27.ProteinMetabolism(46pages,1077-1123)27.1TheGeneticCode(1078-1087)27.2ProteinSynthesis(1088-1114)27.3ProteinTargetingandDegradation(1114-1123)28.RegulationofGeneExpression(42pages,1127-1168)28.1PrinciplesofGeneRegulation(1128-1138)28.2RegulationofGeneExpressioninBacteria(1138-1147)28.3RegulationofGeneExpressioninEukaryotes(1147-1168)
