Download - Cardiovascular system pathology lab
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Cardiovascular System-
Pathology Lab
3rd year medical students
Dr. Nisreen Abu Shahin
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Thrombosis
This picture represents a
bisected abdominal
aorta with advanced
atherosclerosis
complicated by
thrombosis. The blue
lines highlight a
characterestic color
pattern in the thrombus.
1- what are these color
changes called?
2- what is the clinical
significance of these
lines?
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Organizing thrombus
slide # BB69:
1- describe the
changes you see in
the vessel wall.
2- what does the
pink material
(black arrows)
represent?
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Atherosclerosis
slide # BB224:
The microscopic
picture shown
summarizes the
features of
advanced
atherosclerotic
lesions, name
those.
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Infarction
These are examples
of lung infarction
(A), and spleen
infarction (B).
1- what is the type of
the lung infarct?
2- what is the type of
the splenic infarct?
3- what are the
differences between
them?
4- describe the
microscopic features
you expect to see in A
and B.
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A 70 year old man
presents to ER with
severe abdominal pain
and rectal bleeding.
Investigations had lead to
a suspicious sudden
mesentric artery
occlusion. This is a
picture of his small
intestines upon surgery.
1- what is your diagnosis?
2- what type of infarcts is
it? Why?
Infarction
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Aortic dissection
This microscopic
picture is from a
whole thickness
section of the
aorta.
What does the
asterisk
represents?
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Aortic dissection
slide # BB17:
1- what is the most common precipitating cause of this disease?
2- name an autosomal dominant connective tissue disease that can be associated with it?
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Myocardial infarct
1- what does the arrow
represent?
2- what does the
arrowhead represent?
3- what does the
asterisk represent?
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Myocardial infarction
slide # BB208:
1- in old myocardial infarcts, what is the type of tissue that replaces the myocytes?
2- name 3 possible complications of MI.
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Please examine the following jars in
pathology lab:
• 22/18 lung infarction
• 32/14 bowel infarction
• 21/17 early atherosclerosis (fatty streaks)
• 27/17 advanced atherosclerosis
• 46/17 aortic dissection
• 25/17 lt ventricular hypertrophy
• 4/17 old myocardial infarction
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Hemangioma
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A, Characteristic coalescent cutaneous red-purple macules and plaques.
B, Histologic view of the nodular stage, demonstrating sheets of plump, proliferating spindle cells and slitlike
vascular spaces
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Abdominal aortic aneurysm
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Aortic dissection
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Morphology of fatty streaks
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Embolus derived from a lower extremity deep venous thrombosis and now impacted in a pulmonary artery branch
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Red and white infarcts.
Alung
Bspleen
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kidney infarct, now replaced by a large fibrotic scar
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A, Hyaline arteriolosclerosis. The arteriolar wall is thickened with the deposition of amorphous proteinaceous material, and the lumen is markedly narrowed. B, Hyperplastic arteriolosclerosis ("onion-skinning") (arrow) causing luminal obliteration
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Microscopic features of myocardial infarction and its repair.