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CROHN’S DISEASE
Alison Cunliffe
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What is Crohn’s Disease?
Chronic inflammatory disease of the intestines Causes ulcerations, breaks in the lining, of
the small and large intestines, but can affect the digestive system anywhere form the mouth to the anus.
Immune system abnormally activated in the absence of any known invader
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Caused by…
The cause is unknown Some scientists suspect that infection
from certain bacteria may cause the disease No convincing evidence that the disease is
caused by infection
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Symptoms
Abdominal pain Diarrhea Weight loss
Less common Poor appetite Fever Night sweats Rectal pain Rectal bleeding
The symptoms all depend of the location, extent and severity of the inflammation.
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Complications
Intestinal Obstruction and perforation of small
intestine (rare and requires surgery) Abscesses Intestinal bleeding
Also involves the skin, joints, spine, eyes, liver, and bile ducts.
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Treatment
Patients with mild or no symptoms may not need treatment Also, patients in remission may not need
treatment No medication can cure Crohn’s disease Doctors prescribe medication to
1) induce remission 2) maintain remission 3) minimize side effects of treatment 4)improve quality of life
Medication Anti inflammatory agents
antibiotics
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Tests
Blood test Barium x-ray Colonoscopy Computerized axial tomography Endoscopy
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Prognosis
Chronic No prevention
Genetic in origin
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