2013/06/10
1
Eating & Swallowing
Deficits in
Individuals with
Dementia
Rebecca Affoo June 11, 2013
Acknowledgements
Co-Author
• Dr. Ruth Martin, Western University
Eating & Swallowing Deficits in
Individuals with Dementia
Acknowledgements
Support • Ontario Ministry of Health and Long-Term Care
Career Scientist Award
• Western University Graduate Thesis Research
Award
• Alzheimer Foundation London and Middlesex
Doctoral Award
Eating & Swallowing Deficits in
Individuals with Dementia
Today’s Agenda
Systematic Review
Eating & Swallowing Deficits in
Individuals with Dementia
Today’s Agenda
What is Dementia?
Eating & Swallowing Deficits in
Individuals with Dementia
2013/06/10
2
Today’s Agenda
What is the prevalence of
dementia in Canada?
Eating & Swallowing Deficits in
Individuals with Dementia
Today’s Agenda
What do we know about
eating and swallowing
deficits in individuals with
dementia?
Eating & Swallowing Deficits in
Individuals with Dementia
Today’s Agenda
What do we know about
eating and swallowing
assessment, management,
and treatment in this
population?
Eating & Swallowing Deficits in
Individuals with Dementia
Today’s Agenda
Conclusions
Eating & Swallowing Deficits in
Individuals with Dementia
Today’s Agenda
Questions
Eating & Swallowing Deficits in
Individuals with Dementia
Systematic Review
Purpose:
• Describe, synthesize, and interpret
literature on dysphagia and/or
autonomic nervous system
dysfunction in dementia
• Identify gaps in the existing literature
Eating & Swallowing Deficits in
Individuals with Dementia
2013/06/10
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Systematic Review
Methodology:
• Systematic searches of the PubMed,
EBSCOhost, PsychINFO, Cochrane,
EMBASE, and Scopus databases
were conducted
Eating & Swallowing Deficits in
Individuals with Dementia
What is Dementia? • A syndrome caused by progressive
disorders that affect:
• Memory
• Thinking
• Behaviour
• Ability to perform activities of daily
living (ADL)
Eating & Swallowing Deficits in
Individuals with Dementia
What is Dementia?
Eating & Swallowing Deficits in
Individuals with Dementia
Dementia
Alzheimer’s disease
Vascular dementia
Frontotemporal lobe dementia
Lewy body dementia
Parkinson’s disease dementia
What is the Prevalence of
Dementia in Canada?
Eating & Swallowing Deficits in
Individuals with Dementia
What do we know about
eating and swallowing
deficits in individuals with
dementia?
Eating & Swallowing Deficits in
Individuals with Dementia
Dysphagia in Alzheimer’s
Disease (AD) • Prevalence of dysphagia in moderate
and severe AD ~ 32% to 93%
Chouinard et al., 1998
Volicer et al., 1989
Horner et al., 1994 Feinberg et al., 1992
Eating & Swallowing Deficits in
Individuals with Dementia
2013/06/10
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Dysphagia in AD • Dysphagia may occur early in AD
Humbert et al., 2010 Priefer and Robbins, 1997
Eating & Swallowing Deficits in
Individuals with Dementia
Dysphagia in AD • Functional changes to the swallow
may be associated with functional
changes in the cortical swallowing
network
Humbert et al., 2010
Humbert et al., 2011
Eating & Swallowing Deficits in
Individuals with Dementia
Dysphagia in AD • The oral and pharyngeal stages may
be affected
Humbert et al., 2010
Garon et al., 2009
Suh et al., 2009
Wada et al., 2001
Priefer and Robbins, 1997 Horner et al., 1994
Eating & Swallowing Deficits in
Individuals with Dementia
Dysphagia in AD • Dysphagia may occur in all stages of
AD and may be a marker of disease
severity
Wada et al., 2001 Horner et al., 1994
Eating & Swallowing Deficits in
Individuals with Dementia
Dysphagia in AD • Eating and swallowing deficits in AD
appear to be less severe compared
with other types of dementia
Shinagawa et al., 2009 Ikeda et al., 2002
Eating & Swallowing Deficits in
Individuals with Dementia
Behavioural Eating Deficits
in AD • Behavioural eating difficulties may
occur in all stages of AD
Edahiro et al., 2012
Priefer and Robbins, 1997
Durnbaugh et al., 1996
Burge, 1994
Morris et al., 1989
Suski and Nelsen, 1989
Eating & Swallowing Deficits in
Individuals with Dementia
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Dysphagia in Vascular
Dementia (VaD) • The oral and pharyngeal stages may
be affected
Suh et al., 2009
Logemann, 1998
Eating & Swallowing Deficits in
Individuals with Dementia
Dysphagia in VaD • Aspiration rates and silent aspiration
rates appear to be higher than those
of AD patients
Suh et al., 2009
Eating & Swallowing Deficits in
Individuals with Dementia
Dysphagia in VaD
Eating & Swallowing Deficits in
Individuals with Dementia
Suh et al., 2009
Dysphagia in Lewy Body
Dementia (LBD) • Aspiration rates in individuals with
LBD have been found to be 35.6%
Yamamoto et al., 2010
Eating & Swallowing Deficits in
Individuals with Dementia
Dysphagia in LBD • Caregivers report:
• Significantly greater swallowing
deficits with solids and liquids
• Increased difficulty with sputum, loss
of appetite, and constipation
Shinagawa et al., 2009
Eating & Swallowing Deficits in
Individuals with Dementia
Dysphagia in Parkinson’s
Disease Dementia (PDD) • Prevalence of dysphagia in PDD ~ 25%
Bine et al., 1995
Eating & Swallowing Deficits in
Individuals with Dementia
2013/06/10
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Dysphagia in PDD • Individuals may demonstrate an
impaired ability to manipulate food in
the oral cavity
Athlin et al., 1989
Eating & Swallowing Deficits in
Individuals with Dementia
Behavioural Eating Deficits
in PDD • Disabilities may occur in the areas of
concentration, communication,
manipulation of food on the plate, and
transporting food to the mouth
Athlin et al., 1989
Eating & Swallowing Deficits in
Individuals with Dementia
Dysphagia in
Frontotemporal Lobe
Dementia (FTD) • Pharyngeal stages may be primarily
affected
Langmore et al., 2007
Eating & Swallowing Deficits in
Individuals with Dementia
Behavioural Eating Deficits
in FTD • Caregivers have reported swallowing
problems, appetite changes, food
preference changes, and abnormal
eating behaviours
Ikeda et al., 2002
Eating & Swallowing Deficits in
Individuals with Dementia
What do we know about
eating and swallowing
assessment, management,
and treatment in this
population?
Eating & Swallowing Deficits in
Individuals with Dementia
Assessment • Best assessment practices are
currently unknown
Feinberg et al. 1992
Leder et al., 2009
Hansen et al., 2011
Eating & Swallowing Deficits in
Individuals with Dementia
2013/06/10
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Treatment/Management • A physiotherapist administered
cervical spine mobilization protocol
may improve “dysphagia limit” in
individuals with severe AD and altered
neck posture
Bautmans et al., 2008
Eating & Swallowing Deficits in
Individuals with Dementia
Treatment/Management • Thickening liquids to a honey-
thickened consistency may eliminate
thin liquid aspiration in individuals with
dementia
Logemann et al., 2008
Robbins et al., 2008
Hines et al., 2010
Eating & Swallowing Deficits in
Individuals with Dementia
Treatment/Management • High calorie supplements and other
oral feeding options may help
individuals with dementia gain weight
Asplund et al., 1991
Hanson et al., 2011
Eating & Swallowing Deficits in
Individuals with Dementia
Treatment/Management • Treatment with dopamine agonists
and angiotensin-converting enzyme
inhibitors (ACEIs) may result in
positive outcomes in swallowing and
feeding
Yamaguchi et al., 2010
Eating & Swallowing Deficits in
Individuals with Dementia
Treatment/Management • Tube feeding vs. hand feeding
VanOrt and Phillips, 1992
VanOrt and Phillips, 1995
Finucane et al., 1999
Garrow et al., 2007
Sampson et al., 2009
Eating & Swallowing Deficits in
Individuals with Dementia
Conclusions • Demographics
• Nature of Dysphagia
• Contribution to Eating Deficits
• Assessment
• Treatment
Eating & Swallowing Deficits in
Individuals with Dementia
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Conclusions • Correlations
• Neural Mechanisms
Eating & Swallowing Deficits in
Individuals with Dementia
Questions
Eating & Swallowing Deficits in
Individuals with Dementia
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Eating & Swallowing Deficits in
Individuals with Dementia
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Eating & Swallowing Deficits in
Individuals with Dementia
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Individuals with Dementia
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Eating & Swallowing Deficits in
Individuals with Dementia
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Eating & Swallowing Deficits in
Individuals with Dementia
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Eating & Swallowing Deficits in
Individuals with Dementia
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Eating & Swallowing Deficits in
Individuals with Dementia