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Evolu&on and development of cor&cal folding
Reza Rajimehr
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Cor&cal folding
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Why is the cortex folded?
• Dispropor&onate cor&cal expansion • Staying thin • Limited wiring
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The effect of brain size
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The effect of body size
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The effect of encephaliza&on?
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The effect of cor&cal thickness
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Ontogeny of cor&cal folding
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Variability of cor&cal folding in humans
• Normal varia&on • Regional differences • Difference between leI and right hemispheres • No correla&on with age, sex, or brain weight • Correla&on between gyrifica&on and cogni&ve func&ons
• Changes in gyral complexity in pathologies • Cor&cal folding in human twins
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Theories about the forma&on of cor&cal folds
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Grey maMer hypothesis
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Compara&ve anatomy of cor&cal folding
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