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Select-eV: Increasing dimensionality in GC××××GC–TOF MS of environmental
contaminants
Laura McGregor
EMSSIG 2014, 9th July; BAT, Southampton
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Outline
• Select-eV: novel ion-source technology
– What, why and how?
• Select-eV for environmental analyses
– GC×GC–TOF MS
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What is the BenchTOF?
• A reflectron time-of-flight mass spectrometer
• Platform-neutral
• Innovative design
Mass spectrometry at Markes
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Historically…
Variable-energy electron ionisation
70 eV mass spectrum of p-cymene 14 eV mass spectrum of p-cymene
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Variable-energy ionisation
Transition of fragmentation pattern aids structural elucidation
70 eV
16 eV
12 eV
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Case study
GC×GC–TOF MS of environmental matrices
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Water Framework Directive (WFD)
• Lower detection limits
• New monitoring methods and analytical
techniques are now necessary
• Focus is on “priority” substances, but what
about those of emerging concern?
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Emerging contaminants
O
O
O
O
O
P
OO
O
CH3
CH3
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Summary
• Hassle-free soft ionisation
• Improved sensitivity and selectivity
• Reduced matrix impact
• Lower detection limits
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Acknowledgements
• Anthony Gravell, Natural Resources Wales (NRW)
• Graham Mills, University of Portsmouth
• Ian Allan, Norwegian Institute for Water Research NIVA
• Helge E. Roald, Colosseum Clinic (Oslo, Norway)
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This is an excerpt from the original presentation.The full presentation can be downloaded from the Markes website:
http://www.markes.com/Resources/Scientific-
publications/Conference-presentations.aspx