Kim WitmerSenior Vice PresidentChief Financial Officer
Michael Nunn, Ph.D.Executive Director
Research Development
EndocrinologyDevelopmental BiologyNeurobiologyMetabolism
Plant BiologyCognitive Neuroscience
Chemical BiologyBiophotonics
Molecular Biology Cancer Aging Immunology
Gene Therapy Stem Cells
Founded by Jonas Salk in 1970Designated as NCI Basic Center in
1973• Center includes 30 Faculty members• 200 Post-doctoral researchers• 50 Graduate research students
Cancer Center Director: Tony Hunter, Ph.D.
Cancer Center is distributed across Salk• 62% of Institute investigators participate in
Center programs
Salk Institute Cancer Center
Institutional:• Philanthropy• Revenue Diversification• Cost Savings & Efficiencies
Research Development:• Strategies• Innovation Grant Program • Advocacy
Responding to the Fiscal Environment-2014
Operating Revenue by Source
Federal43%
State4%
Founda-tions &
Contribu-tions30%
Corpo-rate5%
HHMI10%
Investment & Other8%
FY13 $109M
Federal61%
State0.5%
Founda-tions &
Contribu-tions
17.0%
Corpo-rate1.5%
HHMI10%
Investment & Other10.0%
FY03 $85M
Note: Excludes subcontracts going out
Increased direct support to Investigators• Increased bridge funding• Raised funds for 21 chairs for Cancer
Center Investigators• Provided Developmental chairs for 5 new
Cancer Center members• Found major donors to build new Core
Resources Biophotonics, Next Gen Sequencing and
Bioinformatics
• Target Cancer Center research in Capital Campaign
Philanthropy
Encourage Investigators to pursue all grant application options
Secured large foundation grant for multiple PI’s & Cores
Developed inter-institutional shared resources
Hired Director of Research Development
Revenue Diversification
Major Administrative Costs Savings
Restructure Mailroom & Telecomm
Central Plant Upgrade – requires less maintenance
ARD – restructuring for efficiency
Procurement – savings
Worker’s Compensation Improvements
Renegotiation of Large Contracts
NIH applications, Awards and Success Rates
The Research Development Office
The office provides –
1. Stewardship and Coaching: Individual R01s Managing Change
2. Launching New Projects: Centers and Programs
3. Seed Funding
4. Advise Senior Leadership
Strategies for Success
1. The Right Opportunity
2. The Right Audience
3. Developing Agency Support
Themes:
Strategies for Success
Agency Websites: NIH Guide
Award Search: NIH RePORTER
The Right Opportunity
Challenges for Cancer Research: Success Rates
2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 20120.0%
5.0%
10.0%
15.0%
20.0%
25.0%
30.0%
35.0%
NCINHLBINIDDKNIAIDNINDSNIGMSNEI
The Right Opportunity
Agency websites – become a pro:funding opportunities✪ NIH http://grants.nih.gov/grants/oer.htm✪ NSF http://nsf.gov/funding/✪ CDMRP http://cdmrp.army.mil/funding/prgdefault.shtml✪ Grants.govfunded projects✪ NIH http://projectreporter.nih.gov/reporter.cfm✪ NSF http://nsf.gov/awardsearch/✪ CDMRP http://cdmrp.army.mil/search.aspx
Automated Funding Announcements:Agency or Commercial
The Right Audience
Who will review your grant?
This is ESSENTIAL information to have
BEFORE you start writing …
Click on the grant number
NIH RePORTER:
StudySection
• http://public.csr.nih.gov/StudySections/Pages/default.aspx
Program Official
Developing Agency Support
• The best time to contact a Program Director?– BEFORE YOU START
– required 6 weeks before submission of grants >$500K– NIDDK asks for 3-6 months notice for large programs
Other Topics:• Summary Statements• Etiquette• Negotiating an Award
The Research Development OfficeLeadership: Push vs. Pull
Challenge for developing new projects and building teams • Pull:
– Investigator has a project and/or team already developed
• Push:– Outsider [President?, Chair?, Executive Director?]
identifies collaborative research
opportunities in line with faculty
research interests
The Research Development Office
The Push – Match opportunities to PIs:
• Find Leaders • Collaborators
– Identify experts (preferably local) to build a team
Sell the project:• Know the competition
– Identify similar funding• Timing of Submission… use NIH RePORTER
P30 Program and External Advisory Board Meetings
The Research Development Office
Sample RDEV projects at the Salk Institute:
NCI Cancer Center Renewals in 2008 and 2013
Sanford Consortium: $43M facility award from CIRM
New Centers, complementing the CCSG
NINDS and NEI P30 awards …
CIRM Center of Excellence in Genomic Medicine
Seed Funding
Salk Innovation Grant Program
•Established in 2006 with donor funding
•Average expenditures $1 million/year
•Awards up to $100K direct costs for one year
•Internal peer review with option for outside critiques
•2 rounds/yr, @ 12 applications, 4 awards
Salk Innovation Grants: Leverage
2007 (9 awards)
2008 (11 awards)
2009 (9 awards)
2010 (7 awards)
2011 (7 awards)
$0
$2
$4
$6
$8
$10
$12
$ 0.9M $1.2M $0.97M $0.85M $0.85M
$3.7 M
$11 M
$7.3 M
$30K
Awarded LeverageIn
Mill
ions
Major new projects seeded by SIG funding:• $5 M Industry partnership program• $2 M ARRA Grand Opportunities Award• $4 M Foundation Award • $4 M for two new NIH R01s
Seed Funding
Cancer Center Pilot Grants
• Initiated in 2009
• Uses NCI CCSG Developmental Funds
• Supports Cancer Focus:– Collaborations
both intra- and inter-programmatic– Translational Research
external, orusing C3 resources (current RFA)
Advocacy – Affecting Change
Administrators can serve as liaison to leaders at Federal and State Agencies – NIH, CIRM, etc.
Administrators can join advocacy and lobbying groups– Association of Independent Research Institutes
(AIRI)
Example: Special Council Review of Well-Funded Investigators
H-index Analysis: Investigators from 4 Cancer Centers at AIRI Institutions
1 2 3 4 5 6 7 8 9 10 11 120
1000
2000
3000
4000
5000
6000
7000
8000
NewRenewalTotal
Analysis of NIH Competing Awards, 2002-2013
1 2 3 4 5 6 7 8 9 10 11 121.40
1.50
1.60
1.70
1.80
1.90
2.00
2.10
2.20
2.30
2.40
ratio type 1/2
ratio type 1/2
Management■Human Resources■Infrastructure
Development Portfolio Diversification
Unrestricted funds Foundation & corporations
Grant Development Seed Funding
Advocacy
Summary
What is your state doing to support Cancer Research?
What management strategies have helped you conserve resources?
Are there alternative approaches to funding start-up projects?
Who you gonna call to change Federal or State policy?
Questions