![Page 1: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/1.jpg)
Lawmakers Call on NIH to Reduce Price of Cancer Drug
By Floyd Arthur
![Page 2: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/2.jpg)
In a move that is becoming more common as drug prices in the United States continue
![Page 3: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/3.jpg)
to soar, a group of Democratic lawmakers is urging the National Institute of Health and
![Page 4: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/4.jpg)
Department of Health and Human Services to hold public hearings into the cost of a
![Page 5: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/5.jpg)
recently introduced cancer drug. In a letter to and NIH Director Francis Collins and
![Page 6: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/6.jpg)
HHS director Sylvia Burwell, the legislators called on the agencies to revoke the patent
![Page 7: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/7.jpg)
on the prostate cancer drug enzalutamide (Xtandi) and make it available at a lower price.
![Page 8: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/8.jpg)
Xtandi is marketed in the United states by San Francisco-based Medivation Inc. and the
![Page 9: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/9.jpg)
Japanese pharmaceutical company Astellas Pharma Inc. Medivation’s stock price
![Page 10: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/10.jpg)
dropped 6 percent after the letter was made public last week.
![Page 11: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/11.jpg)
The letter was signed by presidential candidate Sen. Bernie Sanders,Texas Democrat
![Page 12: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/12.jpg)
Rep. Lloyd Doggett and Rep. Peter Welch of Vermont.
![Page 13: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/13.jpg)
Cancer Drug Was Developed with Public Funds
![Page 14: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/14.jpg)
Xtandi was developed with the help of research conducted at the University of California
![Page 15: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/15.jpg)
Los Angeles, which is supported by taxpayer funded grants. “Under current law, NIH
![Page 16: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/16.jpg)
can take this step if federal funds supported a drug's development and the company is
![Page 17: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/17.jpg)
selling it at an unreasonably high price," the lawmakers said.
![Page 18: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/18.jpg)
Xtandi sells for $129,000 for a one year supply in the United States. The price for the
![Page 19: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/19.jpg)
same quantity of the drug in Canada is $39,000. In Sweden and Japan it is $30,000 per year.
![Page 20: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/20.jpg)
"When Americans pay for research that results in a pharmaceutical, that drug should be
![Page 21: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/21.jpg)
available at a reasonable price," said Doggett. "An unaffordable drug is 100 percent
![Page 22: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/22.jpg)
ineffective.” Doggett is co-chair of the House Democratic Caucus Prescription Drug Task Force.
![Page 23: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/23.jpg)
Astellas responded to the letter by saying that most patients with private insurance or
![Page 24: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/24.jpg)
Medicare pay just $25 per month for the prostate cancer drug; insurers or Medicare pick
![Page 25: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/25.jpg)
up the rest. Additionally, Astellas provides the drug free of charge to those who have no
![Page 26: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/26.jpg)
insurance and a combined family income of $100,000 or less.
![Page 27: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/27.jpg)
Drugmakers Under Fire as Drug Prices Soar
![Page 28: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/28.jpg)
Medivation and Astellas are not the first drugmakers to find themselves in Congress’
![Page 29: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/29.jpg)
crosshairs this year. On March 25, J. Michael Pearson, outgoing CEO of Montreal-
![Page 30: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/30.jpg)
based Valeant Pharmaceuticals International Inc., was subpoenaed to appear before the
![Page 31: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/31.jpg)
Senate Aging Committee to answer questions about Valeant’s pricing practices. Under
![Page 32: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/32.jpg)
particular scrutiny are two heart medications, Isuprel and Nitropress (nitroprusside),
![Page 33: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/33.jpg)
which Valeant acquired in 2015. The company subsequently raised the price of the drugs
![Page 34: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/34.jpg)
by 525 percent and 212 percent respectively.
![Page 35: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/35.jpg)
Both Isuprel and Nitropress have been available for years. In 2012, the price of both
![Page 36: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/36.jpg)
drugs was $44.50 per vial. In December, 2013, the drugmaker Marathon
![Page 37: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/37.jpg)
Pharmaceuticals LLC acquired the rights to both drugs and raised the prices to about
![Page 38: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/38.jpg)
$218 each, a hike of nearly 400 percent.
![Page 39: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/39.jpg)
In 2015, Valeant raised the price of the drugs to $1,346.62 and $805.60 respectively.
![Page 40: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/40.jpg)
This and other cases of drugmakers buying up the rights to old drugs and then raising
![Page 41: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/41.jpg)
the prices excessively have been the subject of multiple Congressional hearings since
![Page 42: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/42.jpg)
2014. The issue came to a head last year when Turing Pharmaceuticals, headed by then-
![Page 43: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/43.jpg)
CEO Martin Shkreli, acquired the drug Daraprim. Turing immediately raised the price
![Page 44: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/44.jpg)
of the drug, which is used to treat toxoplasmosis, 5000 percent, from $13.50 to $750 a pill.
![Page 45: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/45.jpg)
Shkreli was vilified in the press and social media, and was later forced to appear before
![Page 46: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/46.jpg)
the House Committee on Oversight and Government Reform. Shkreli, who is now under
![Page 47: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/47.jpg)
federal indictment for securities fraud, invoked his Fifth Amendment right against self-
![Page 48: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/48.jpg)
incrimination and refused to testify.
![Page 49: Lawmakers call on nih to reduce price of cancer drug by Floyd Arthur (PPT)](https://reader035.vdocument.in/reader035/viewer/2022070601/587f34901a28ab121d8b6ab5/html5/thumbnails/49.jpg)
Pearson will appear before the Senate Aging Committee on April 27, 2016.