Lymphatic vessels:Removes extracellular fluid (lymph) from the lamina propria.Absorb fat and transport as chyle. Transport lymphocytes and other cells, such as tumor cells.
Lymphatic tissues:Diffuse lymphatic tissues and cells
Solitary nodulesAggregates of nodules (Peyer’s patches) Tonsils Lymph nodes (filters lymph) Spleen (filters blood) Thymus (T cell differentiation) Bone marrow (source of lymphocytes)
Ross and Pawlina, p.397
Ross and Pawlina, p. 417
#27 Lymph node
Cortex
Medulla
Hilu
s
#26 Lymph Nodealso #142
Subcapsular sinus
Trabecular sinus
Medullary sinuses
Hilus
Efferent lymphatic ducts
Blood vessels
Secondary follicles
Medullary cords
Direction of lymph flow through a
lymph node
Afferent lymphatic vessel
Subcapsular sinus
Trabecular or perinodular sinus
Medullary sinus
Efferent lymphatic vessel
Thoracic duct
Left subclavian vein
General circulation
Ross and Pawlina, p. 419
To lymph nodes
(Left side)
Another lymph node….
#26 Lymph Node: secondary follicle
Germinal center: lymphoblasts
HEV
Subcapsular sinus
#26 Lymph Node: Medullary cords and sinuses (also #142)
M. Cord: lymphocytes plasma cells
M. sinus reticular cells lymphocytes macrophages
#30 Lymph Node
Afferent lymphatic ducts
#30 Lymph Node: deep cortex
High Endothelial Venules
High endothelial venules: longitudinal sections
#142 Lymph Node H&E
#28: silver stain Reticular fibers in medullary sinus
Solitary nodules #161 &157
Aggregates of nodules
#175, UCSF 261, 168
#161
#261
#168 (jejunum) Intraepithelial lymphocytes
Palatine tonsil: covered with stratified squamous epithelium which invaginates to line the surface of the crypts