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Mutant Gene Identified That Causes Abnormal Chromosome Count, Leading to Cancer
Inexpensive Method Detects ALK Rearrangement in Lung Cancer Patients
DANIEL ALEJANDRO SALDARRIAGA
MEDICINE STUDENT
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INTRODUCTION
Some studies have helped humans increasing all the creations they’ve gotten.Using diffferent techniques to look for new solutions, for example, gene mapping.
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• The researchers fouond a gene that is changed in human cancers creating an anueplidy.
• It generates an abnormal number of chromosomes.
MUTANT GENE IDENTIFIED THAT CAUSES ABNORMAL CHROMOSOME COUNT, LEADING TO CANCER. SCIENCEDAILY (AUG. 18, 2011).
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• Usually the part the is missing is called STAG2.
• The main cancers where this gene is mutated are in:
- Glioblastoma multiforme
- Malignant Melanoma
- Ewing's sarcoma
MUTANT GENE IDENTIFIED THAT CAUSES ABNORMAL CHROMOSOME COUNT, LEADING TO CANCER. SCIENCEDAILY (AUG. 18, 2011).
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• The inactivation of this gene doesn’t regulate the cellular division.
• Of that way begins the fight against cancer.
• And every peace un cells starts the dision.
MUTANT GENE IDENTIFIED THAT CAUSES ABNORMAL CHROMOSOME COUNT, LEADING TO CANCER. SCIENCEDAILY (AUG. 18, 2011).
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• When they identify the mutation they used a technique, that perform the mutant genes.
• It makes easier researchers’ life and doctor’s life too.
MUTANT GENE IDENTIFIED THAT CAUSES ABNORMAL CHROMOSOME COUNT, LEADING TO CANCER. SCIENCEDAILY (AUG. 18, 2011).
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OBSERVATION
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• Students discoverded that happiness can be in any place.
• They wanted to make easier lives and they make their dream come true. Only trying and trying.
INEXPENSIVE METHOD DETECTS ALK REARRANGEMENT IN LUNG CANCER PATIENTS. SCIENCEDAILY (AUG. 2, 2011) .
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• Lung cancer patients with ALK rearrangement gave a good response to crizotinib.
• FISH is conseidered the main method for detecting the ilness.
INEXPENSIVE METHOD DETECTS ALK REARRANGEMENT IN LUNG CANCER PATIENTS. SCIENCEDAILY (AUG. 2, 2011) .
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• The researchers created CISH (chromogenic in situ hybridization).
• Comparing it with fish detecting faster a mutatant gene.
INEXPENSIVE METHOD DETECTS ALK REARRANGEMENT IN LUNG CANCER PATIENTS. SCIENCEDAILY (AUG. 2, 2011) .
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• There was a big agreement between FISH and CISH.
• CISH, gave good results, for the study.
• Two international Institutes gave help and trust them.
INEXPENSIVE METHOD DETECTS ALK REARRANGEMENT IN LUNG CANCER PATIENTS. SCIENCEDAILY (AUG. 2, 2011) .
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OBSERVATION
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• These researches are a good entrance for scientific world, increasing the search rate for access to research about different illness.
MEDICINE UTILITY
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• Knowing how to work every gen and the effects that they make if they’re mutated are very importan in the medical practice.
MEDICINE UTILITY
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• Several changes we can make if we know the mechanism of a gene.
• Cancer has shown that is very dificult cutting it off, till today.
MEDICINE UTILITY
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• New treatments get set better every life. For that reason is important help the studies to grow up and trust them to receive the apropiate response.
MEDICINE UTILITY
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BIBLIOGRAPHY• MARTINEZ S. Lina María . Biología molecular . 6 . Ed. Medellín: FACULTAD DE MEDICINA.
Páginas 134-139.
•
• Mutant Gene Identified That Causes Abnormal Chromosome Count, Leading to Cancer. ScienceDaily (Aug. 18, 2011).
•
• Inexpensive Method Detects ALK Rearrangement in Lung Cancer Patients. ScienceDaily (Aug. 2, 2011) .
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GRACIAS