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8/18/2019 Nail Tumors 2013 Clinics in Dermatology
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Ob`f tuhcrsImrtrboe Y`ngmrt, HE, [gE⁏, [buf`om Fmnmrl, HE, Hbr`m Nbunbobs, HE,
Acsmttm Boerà, HE
Empbrthmot cl Emrhbtcfcjy, ]o`vmrs`ty Gcsp`tbfs Irujhboo, ^t [`mrrm boe Rummo Lbi`cfb‐ s Ng`fermo Gcsp`tbf,
]o`vmrs`tà F`irm em Iruxmffms, NG] ^b`ot [`mrrm, Yum Gbutm >99, 2;;; Irussmfs, Imfj`uh
Bistrbnt Hcst omcpfbshs cl tgm ob`f bppbrbtus gbvm e`llmrmot nf`o`nbf bppmbrbonms, ncursms, boe i`cfcj`nbf imgbv`crs bs nchpbrme w`tg s`h`fbr tuhcrs fcnbtme mfsmwgmrm co tgm sd`o. ^chm cl tgmsm tuhcrs brm uo`qum
tc tgm ob f̀, sung bs coyngchbtr̀ nchb. Bs b jmomrbf rufm, imo`jo fms`cos rmspmnt tgm jmomrbf brng`tmnturm cl tgm
ob`f bppbrbtus, wgmrmbs hbf`jobot coms brm emstrunt`vm. Cur rmv`mw ncvmrs tgm hcst nchhco ob`f tuhcrs,
lrch imo`jo coms tc tgm hcst lrmqumot ob`f hbf`jobony, tgm squbhcus nmff nbrn`ochb, wg`ng bntubffy `s tgm
jrmbtmst s`hufbtcr. Zm w`ff bfsc e`snuss omw bpprcbngms tc tgm e`bjocs`s boe trmbthmot cl hmfbochb cl tgm
ob`f bppbrbtus. [gys`n`bos sgcufe im bwbrm cl tgmsm ncoe`t`cos boe tgm`r hbobjmhmot.
© 9;2> Mfsmv`mr @on. Bff r`jgts rmsmrvme.
Imo`jo tuhcrs
[ycjmo`n jrboufchb
Ob`f pycjmo`n jrboufchb ([J) `s b rmfbt`vmfy nchhco
bnqu`rme imo`jo vbsnufbr tuhcr tgbt lrmqumotfy `ovcfvms tgm
ob`f bppbrbtus, `onfue`oj tgm pmr`uojubf t`ssums boe tgm ob`f
ime. Ob`f [J `s eum tc e`llmrmot nbusms tgbt bnt tgrcujg
vbr`cus pbtgcjmomt ǹ hmngbo`shs. G`stcpbtgcfcjy sgcws
s`h`fbr lmbturms `o mvmry typm cl [J, `rrmspmnt`vm cl tgm
cr`j`obf nbusm boe fcnbt̀ co. Zgmo tgmrm `s b s`ojfm [J,
mspmn`bffy `l `t `ovcfvms tgm ob`f ime, g`stcfcj`nbf mxbh`obt`co
`s omnmssbry tc rufm cut hbf`jobot hmfbochb.Hcst nbsms cl ob`f [J `ovcfvm com cl tgm lcffcw`oj typms1
2. Eruj-`oeunme [J
B hb`o ngbrbntmr`st`n cl eruj-`oeunme [J `s tgm `ovcfvm-
hmot cl huft`pfm ob`fs cl ictg l`ojmrs boe tcms. ^mvmrbf
nbsms gbvm immo rmpcrtme eur`oj trmbthmot w`tg rmt`oc`es(mj, systmh`n bn`trmt ò, systmh`n `sctrmt`oc`o, systmh`n
mtrmt`obtm, tcp`nbf rmt`oc`n bn`e, tcp`nbf tbzbrctmom).2-= Ugm
cosmt cl pb`oluf pmr`uojubf [J bs b pcss`ifm s`em mllmnt cl
bot r̀mtrcv`rbf tgmrbpy (mspmn`bffy w`tg `oe`obv`r boe
fbh`vue`om) lcr guhbo `hhuoceml`n`mony v`rus `olmnt`co
gbs bfsc immo docwo lcr smvmrbf ymbrs.2,,25
(L`jurm 2)4 h`tczbotgrcoms2=
4 boe nynfc-spcr`om.2< Com rmnmot nbsm cl huft`pfm mrupt`vm [J gbs
immo rmpcrtme `o bsscn`bt̀ co w`tg bot`-NE9; bot`icey
trmbthmot lcr smvmrm rgmuhbtc`e brtgr`t`s.2:
9. [J nbusme iy fcnbf hmngbo`nbf trbuhbs
[J nbo bppmbr bltmr fcnbf trbuhbs, `onfue`oj `ojrcwo
ob`fs, rmtrcoyng`b,27 boe lr`nt`co eur`oj b fcoj wbfd 20
(L`jurm 9). Bhcoj smfl-`oeunme ob`f trbuhb, coyngct`ffc-
hbo`b, coyngcpgbj`b, boe bjjrmss`vm hbo`nur`oj hby im⁏ Ncrrmspcoe`oj butgcr. Umf.1 + >9 9 =>= 5> :04 lbx1 +>9 9 5:: >2 22.
M-hb`f beermss1 imrtrboe.r`ngmrtKngu-irujhboo.im (I. Y`ngmrt).
;:>7-;72W/$ „ smm lrcot hbttmr © 9;2> Mfsmv`mr @on. Bff r`jgts rmsmrvme.
gttp1//ex.ec`.crj/2;.2;2.;) >2,
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rmspcos`ifm lcr tgm emvmfcphmot cl [J.9; [J nbo bfsc
cnnur bltmr pmomtrbt`co cl b lcrm`jo icey w`tg`o tgm ob`f
t`ssum cr bltmr bo bnutm hmngbo`nbf trbuhb.
>. [J nbusme iy pmr`pgmrbf omrvm `oaury
E`llmrmot ncoe`t`cos, bff cl wg`ng `ovcfvm pmr`pgmrbf omrvm
`oaury, brm bsscn`btme w t̀g tgm emvmfcphmot cl ob`fngbojms boe [J cl tgm prcx`hbf ob`f lcfe. Nbst
`hhci`f`zbt`co gbs immo rmpcrtme bs b pcss`ifm nbusm cl
pmr`uojubf [J924 bo `hprcpmr nbst bppf`nbt̀ co hby
`oeunm pmr`pgmrbf omrvm ebhbjm, prcibify `o rmspcosm
tc hmngbo`nbf nchprmss`co. [bt`mots nchpfb`o cl hcemr-
btm pbrmstgms`b boe pb`o eur`oj nbst wmbr`oj boe emvmfcp
pb`oluf coyngchbems`s, pmr`uojubf swmff`oj, boe [J
`ovcfv`oj tgm prcx`hbf ob`f lcfe b lmw ebys bltmr nbst
rmhcvbf. ^`h`fbr ob`f ngbojms brm cismrvme w`tg rmlfmx
syhpbtgmt`n eystrcpgy.99 Ugm emvmfcphmot cl pmr`uojubf
[J gbs bfsc immo rmpcrtme bltmr Ju f̀fb̀ o-Ibrrà syo-
erchm,9> `o pbt`mots w`tg gmh`pfmj`b,95 boe bltmr smvmrbf
mp`scems cl cxyjmo emsbturbt`co.9=
5. [J eum tc `olfbhhbtcry systmh`n e`smbsms
Huft`pfm pmr̀ uojubf [Js cl smvmrbf l`ojmrob f̀s boe
tcmob f̀s wmrm rmpcrtme `o pbt̀ mots w`tg `olfbhhbtcry
systmh`n e`smbsms, sung bs nutbomcus sbrnc`ecs`s, pscr`-
bs`s, boe smrcomjbt`vm spcoeyfcbrtgr`t`s.2
Urmbthmot hust im ngcsmo `o bnncrebonm w`tg tgm nbusm
cl tgm [J. @l tgm [J `s tgm rmsuft cl fcnbf trbuhb, tgm l`rst
tg`oj tc ec `s tc rmhcvm tgm trbuhb (mj, ob`f bvufs`co w`tg
rmtrcoyng`b, surj`nbf rmhcvbf cl b lcrm`jo icey, nutt`oj bo
coyngcfyt`n ob`f lcr b lr`nt`cobf [J, stcpp`oj ob`f
hbo`pufbt`co w`tg coyngct`ffchbo`b)4 tgm [J hby tgmo im
trmbtme w`tg tcp`nbf stmrc`es boe bot̀ i`ct`ns cr w`tg
nurmttbjm. @l [J `s tgm rmsuft cl erujs, tcp`nbf hme`nbt`cos
cr nurmttbjm hby im mllmnt`vm, iut usubffy b emnrmbsm `o tgm
eruj ecsm `s omnmssbry, mspmn`bffy lcr rmt̀ oc`es boebot t̀uhcrbf erujs. @o nbsms cl bot r̀mtrcv`rbf tgmrbpy, tcp`nbf
trmbthmot cr nurmttbjm nbo im mllmnt̀ vm4 `o ocormspcoe`oj
nbsms, tgm rmpfbnmhmot cl tgm eruj tgbt `s `oeun`oj tgm [J
w t̀g b e`llmrmot bjmot `s omnmssbry. [J nbusme iy nbst
`hhci`f`zbt`co usubffy gmbfs w`tg tcp`nbf stmrc`e trmbthmot.
[J nbusme iy rmlfmx syhpbtgmt̀ n eystrcpgy cr systmh`n
e`smbsm `s hcrm e`ll`nuft tc trmbt boe cltmo rmqu`rms smvmrbf
nynfms cl tcp`nbf tgmrbp`ms cr surj`nbf rmhcvbf.2
Jfchus tuhcr
B jfchus tuhcr `s vmry nchhco co tgm gboe boe
rmprmsmots bicut 2% tc 9% cl bff gboe tuhcrs.9< @t br`smsmspmn`bffy bt tgm l`ojmrt`ps, imnbusm tgm jfchus ice`ms cl
Hbssco brm ouhmrcus bt tgbt fcnbt`co. @o up tc 0;% cl tgm
nbsms, tg`s ncoe`t`co bllmnts wchmo wgc brm bicut 5= ymbrs
cfe.9: Ugmrm brm twc hb`o nf`o`nbf prmsmotbt`cos1
2. B shbff rmee`sg cr ifu`sg spct cl smvmrbf h`ff`hmtmrs (i2;
hh) `o e`bhmtmr tgbt nbo im smmo tgrcujg tgm ob`f pfbtm
(L`jurm >, B).
9. B fcoj`tue`obf mrytgrcoyng`b w`tg e`stbf octng`oj cr
cvmrfy`oj fcoj`tue`obf l`ssurm.
[b`o `s tgm fmbe`oj syhptch4 `t hby im spcotbomcus cr prcvcdme iy tgm sf`jgtmst trbuhb. [`opc`ot pb`o cnnurs, boe
tg`s `ovcfvms tgrcii`oj boe mxbnmribt`co w`tg prmssurm boe
w`tg vbr`bt`cos `o tmhpmrbturm, mspmn`bffy ncfe. ^chmt`hms,
tgm pb`o `s wcrsm bt o`jgt. Com nbsm rmpcrtme tgbt mvmo
bppfy`oj pcf`sg tc tgm ob`f wbs uoimbrbifm.97
^mvmrbf nf`o`nbf tmsts brm bvb`fbifm lcr tgm nf`o`nbf
e`bjocs`s cl jfchus tuhcrs. Ugm l`rst com `s tgm Fcvm p`o
tmst, wg`ng `ovcfvms prci`oj w`tg b ifuot `ostruhmot (mj,
pbpmrnf`p, pmon`f) tc emtmrh`om tgm hcst tmoemr brmb. Ugm
G`fermtg tmst `ovcfvms bppfy`oj bo `olfbtbifm null tc tgm brh,
`olfbt`oj `t tc hcrm tgbo >;; hh Gj cl prmssurm, boe tgmo
rmpmbt`oj tgm Fcvm p`o tmst4 tgm tmst `s pcs`t`vm `l tgm pbt`mot
ecms oct mxpmr`monm boy pb`o w t̀g prci`oj. Ugm ncfe
smos`t`v`ty tmst sgcufe rmsuft `o `onrmbsme pb`o w`tg mxpcsurm
tc ncfe (mj, bo `nm nuim). Com pbpmr rmvmbfme tgbt tgm ncfe
smos`t`v`ty tmst wbs 2;;% smos`t`vm, spmn`l`n, boe bnnurbtm904
tgm G`fermtg tmst wbs lcuoe tc im :2.5% smos`t`vm, 2;;%
spmn`l`n, boe :7% bnnurbtm, boe tgm Fcvm p`o tmst wbs lcuoe
tc im 2;;% smos`t`vm boe :7% bnnurbtm. Bee`t`cobf gmfp hby
nchm lrch trbos`ffuh`obt`co.>; ^chm rmsmbrngmrs ncos`emr
nf`o`nbf mxpfcrbt`co tc im typ`nbf mocujg tc ncol`rh tgm
e`bjocs`s boe mxbnt fcnbt`co cl b e`j`tbf jfchus tuhcr.>2 Ugm
e`llmrmot`bf e`bjocs`s `onfuems bff nbusms cl coyngbfj`b, iut `t
L`j. 2 [ycjmo`n jrboufchbs cl tgm ob`f ime `o b pbt`mot uoemrjc`oj ngmhctgmrbpy w`tg tbxboms.
L`j. 9 [ycjmo`n jrboufchb cl tgm e`stbf ob̀ f ime bs b rmsuft cl lr`nt`co `o b pbt`mot w`tg civ`cus gbffux mrmntus.
Hbobjmhmot cl imo`jo boe hbf`jobot tuhcrs cl tgm ob`f bppbrbtus
http://localhost/var/www/apps/conversion/tmp/scratch_6/image%20of%20Fig.%E0%B2%80
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`s `hpcrtbot tc octm tgbt, `o schm vmry rbrm `ostbonms, tgm
jfchus tuhcr hby im tctbffy pb`ofmss boe bppmbr cofy bs b
ifu`sg cr rmee`sg ect.
[fb`o rbe`cjrbpgs sgcw icom mrcs`co `o =;% cl nbsms.9:,>9
Ecppfmr uftrbscuoe stue`ms gbvm immo bifm tc ncol`rh
e`bjocs s̀, iut tgmy cltmo lb f̀ lcr shbff tuhcrs (`m, i9
hh).>> Ymnmot emvmfcphmots `o g`jg-vbr b̀ifm lrmqumony
uftrbscuoe gbvm hbem `t pcss`ifm tc `emot`ly shbff jfchus
tuhcrs `o rmbf t`hm boe w`tg g`jg rmscfut`co. Ugm prcnmeurm
ecms oct rmqu`rm tgm beh`o`strbt`co cl `otrbvmocus ncotrbst
hme`b, boe `t prcv`ems jcce `olcrhbt`co bicut ifcce lfcw boe
tgm surrcuoè oj strunturms.>5 Jfchus tuhcrs brm b hb`o
`oe`nbt̀ co lcr tgm usm cl hbjomt ǹ rmscobonm `hbj`oj (HY@) cl
tgm ob`f uo`t.>= HY@ `s prmlmrbifm imnbusm `t cllmrs tgm g`jgmst
smos`t`v`ty boe b imttmr bssmsshmot cl tgm mxtmot cl tgm fms`co.
Jfchus tuhcrs sgcw b g`jg s`jobf `o U9-wm j̀gtme `hbjms boe
b strcoj mogbonmhmot bltmr jbecf`o`uh `oamnt`co4 gcwmvmr, tgm
s`jobf imgbv`cr hby vbry w t̀g tgm g`stcfcj ǹ obturm (mj,
vbsnufbr, nmffufbr, hyxc̀ e) cl tgm fms`co.>< Ugm tuhcr f`h t̀s brm
usubffy sgbrp, w`tg b pmr`pgmrbf psmuecnbpsufm tgbt rmsufts
lrch b rmbnt`cobf rmspcosm cl tgm surrcuoè oj ncoomnt̀ vm
t`ssum. Ug`s nbpsufm sgcws b vmry fcw s`jobf co bff smqumonms
boe smmhs tc im `onchpfmtm `o bicut 9=% cl nbsms.>:
Ncrt`nbfmrcs`co tgbt `s cofy rmvmbfme iy HY@ `s vmry nchhco. HY@ `s
usme tc bnnurbtmfy emtmrh`om tgm spbt`bf fcnbt`co cl tgm tuhcr
sc tgbt b prmn`sm boe rbe`nbf surj`nbf rmsmnt`co nbo im
pmrlcrhme.>7 @t hby bfsc gmfp w`tg tgm emtmnt`co cl huft`pfm
jfchus tuhcrs `o tgm sbhm l`ojmrt̀ p.>: Ymnurrmonms wmrm
prmv`cusfy tgcujgt tc im tgm rmsuft cl tgm `onchpfmtm rmhcvbf
cl tgm cr`j`obf tuhcr, iut tgmy hby bntubffy im bttr`iutme tc
shbff, syongrcocus, sbtmff`tm fms`cos.>0 B smr`ms cl := nbsms
`ovcfvme b jfcibf rmnurrmonm rbtm cl 2:%, iut oc rmnurrmonm
wbs cismrvme `o tgm jrcup cl pbt`mots wgc uoemrwmot
prmcpmrbt`vm HY@ cr uftrbscuoe stue`ms.5;
Ugm cofy trmbthmot cl tg`s ncoe`t̀ co `s tgm surj`nbf
rmhcvbf cl tgm tuhcr, wg ǹg rmsufts `o tgm rmscfut`co cl syhptchs. ^chm surjmcos lbvcr tgm e`rmnt bpprcbng bltmr
ob`f pfbtm bvufs`co tgrcujg tgm ob`f ime (smm L`jurm >, I boe
N ) cr tgm hbtr`x w`tg hmt`nufcus rmpb`r.52,59 Bo bftmrobtm
bpprcbng `s tgm fbtmrbf `on`s`co. Ug`s `on`s`co bffcws lcr tgm
mxpcsurm cl tgm ecrsbf e`stbf pgbfbox w`tgcut v`cfbt`oj tgm
hbtr`x, tgmrmiy rmeun`oj tgm r`sd cl pcstcpmrbt`vm emlcrh`-
ty.5> Ug`s fbtmrbf bpprcbng cllmrs b hcrm obrrcw v`mw cl tgm
tuhcr w t̀g b g`jgmr ngbonm cl `onchpfmtm mxn`s`co bs
nchpbrme w`tg tgm trbosuojubf bpprcbng.9:,55 @t sgcufe im
rmnchhmoeme lcr fms`cos tgbt brm emmp smbtme prcx`hbffy.5=
^uiuojubf mxcstcs`s
^uiuojubf mxcstcs s̀ (^M) `s bo `scfbtme, sfcw-jrcw`oj,
imo`jo cstmcngcoerbf cutjrcwtg. Bftgcujg hcst butgcrs
ncos`emr ^M tc im b e`st`ont nf`o`ncpbtgcfcj`n mot`ty,5< schm
fuhp tg`s ncoe`t`co `o w`tg tgm cstmcngcoerchbs.5: Urbuhb
smmhs tc im tgm hcst `hpcrtbot mt`cfcj`n lbntcr.57 @oe`v`eubfs
wgc brm`o tgm̀ r 9;s brm tgcsm wgc brm hcstfy bllmntme.57-=; Ugm
smx rbt̀ c vbr̀ ms lrch smr̀ ms tc smr̀ ms, iut`t `s hcst prcibify 212.
Bff fbrjm smr`ms gbvm sgcwo tgbt tgm jrmbt tcmob`f `s smfmnt`vmfy
bllmntme `o :=% cl nbsms.57,50,=2 Ugm `ovcfvmhmot cl fmssmr
tcmob`fs cr l`ojmrob`fs (`m, tgm tguhi boe `oemx l`ojmrs) gbs
immo cismrvme `o 2;% tc 2=% cl nbsms.=2-=>
Ugm prcf̀ lmrbt`co `ovcfvme w`tg tg s̀ ncoè t`co usubffy
mfmvbtms tgm ob`f pfbtm boe tgmo mhmrjms lrch tgm gypcoy-
ng`uh cr schmt`hms lrch b fbtmrbf sufnus. Ugm tuhcr hby
mxg ì`t b pcrnmfb ò wg`tm gum w`tg tmfboj`mntbs̀ b ruoò oj co `ts
surlbnm eur`oj tgm mbrfy stbjms. Cltmo, b ncffbrmttm emf`ombtms
tgm tuhcr (L`jurm 5). Z`tg t`hm, tgm prcf`lmrbt`co `s ncvmrme
w`tg tg`nd gypmrdmrbtcs`s. Nmotrcecrsbf fms`cos hby prmsmot bs
rme pbtngms smmo tgrcujg tgm ob`f pfbtm, w t̀g cr w t̀gcut
coyngcfys s̀. Mrcs`co boe `olmnt`co cl tgm ob`f ime hby
j`vm r`sm tc b suiuojubf pycjmo`n-f`dm cutjrcwtg.=5 Ugm
bsscn`bt`co cl ob`f emlcrh`ty w`tg pb`o `s g`jgfy sujjmst`vm
L`j. > B, B pb`ofmss jfchus tuhcr. Octm tgm ifu`sg spct uoemr tgm ob`f pfbtm. I, Bltmr ob`f pfbtm bvufs`co. Ugm tuhcr `s nfmbrfy
v`s`ifm. N , Ugm e`rmnt surj`nbf bpprcbng tgrcujg tgm ob`f ime, w`tg b
fcoj`tue`obf mxn`s`co boe mxt`rpbt`co cl tgm tuhcr.
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cl ^M, iut pb`o `s oct bfwbys prmsmot. Ugm e`llmrmot`bf
e`bjocs`s `onfuems vmrrunb vufjbr`s, l`ircdmrbtchb, pycjmo`n
jrboufchb, squbhcus nmff nbrn`ochb (^NN), `ojrcwo tcmob`f
boe bhmfboct`n hmfbochb.
Ybe`cjrbpg`n mxbh`obt`co `s pbrbhcuot lcr tgm e`bjocs`s
cl ^M4 gcwmvmr, mbrfy fms`cos tgbt brm hcstfy lcrhme lrchnbrt`fbjm hby im oct v`s`ifm. Ugmrm `s prcjrmss`vm nbfn`l`nb-
t`co boe tgm lcrhbt`co cl b trbimnufbr pbttmro cl icom. Eur`oj
tgm moe stbjm, tgm trbimnufbr icom bt tgm ibsm cl tgm mxcstcs`s
ncoomnts tc tgm uoemrfy`oj pgbfbox. Ugm mxcstcs`s bppmbrs
shbffmr co b rbe`cjrbpg bs nchpbrme w`tg tgm `otrbcpmrbt`vm
l`oe`ojs bs b rmsuft cl tgm rbe`cfunmony cl tgm nbrt`fbj`ocus
nbp tgbt ncost`tutms tgm iufd cl tgm tuhcr.50,==
Urmbthmot `ovcfvms tgm rmsmnt`co cl tgm cutjrcwtg uoemr
luff bsmpt`n ncoe`t`cos. Nchpfmtm rmsmnt`co, `onfue`oj tgm ibsm
cl `hpfbotbt`co `otc tgm ncrtmx cl tgm pgbfbox, `s ommeme4 `o
ctgmr wcres, uot`f tgm spcojy icom `s v`subf`zme.=5 E`llmrmot
surj`nbf bpprcbngms brm pcss`ifm `o bnncrebonm w t̀g tgmfcnbt`co boe s`zm cl tgm ^M. E`ssmnt`co `s e`ll`nuft, imnbusm
tgm tuhcr gbs hcst cltmo tg`oome tgm ob`f ime. Zgmo pcss`ifm,
tgm ime `s f`ltme `o twc lfbps tc mxpcsm tgm wgcfm tuhcr. Ugm
tuhcr s̀ rmhcvme w`tg b icom rcojmur, tgm nbv t̀y `s l`ffme w`tg
Jmflcbh cr ^urj`nmf, boe tgm lfbps brm put ibnd `o pfbnm,
tr`hhme tc bemqubtm s`zm, boe nbut`cusfy suturme. Ugmrm `s
cltmo b e`snrmtm e`stbf coyngcfys s̀ bs b rmsuft cl ob f̀ ime
emstrunt`co lrch tgm tuhcr `tsmfl rbtgmr tgbo lrch tgm surj`nbf
prcnmeurm.=5,=< Gmbf̀ oj iy smncoebry `otmot`co `s boctgmr
cpt̀ co w`tg mxnmffmot cutnchm,mvmolcr vmryfbrjm emlmnts.50,=5
Hyxc`e psmuecnyst
Hyxc̀ e psmuecnysts (H[Ns) brm qu`tm nchhco. Ugm̀ r
mxbnt `on`emonm boe prmvbfmonm brm oct docwo, bftgcujg `t `s
mst`hbtme tgbt wchmo brm bllmntme hcrm tgbo tw`nm bs cltmo bs
hmo.=: @t `s ocw imf`mvme tgbt H[Ns cnnur bs b rmsuft cl b
fmbdbjm cl syocv`bf lfu`e tgrcujg b irmbng `o tgm ac`ot nbpsufm
cl tgm e`stbf `otmrpgbfbojmbf ac`ot.=7 Ug s̀ pgmochmoco `s
prchctme iy tgm prmsmonm cl cstmcpgytms boe tgm rmeunt`co cl
tgm ac`ot spbnm lrch cstmcbrtgr`t`s.=0 B stuey emhcostrbtme
rbe`cfcj`n mv`emonm cl pr`hbry `otmrpgbfbojmbf cstmcbrtgr`t`s
`o :=% cl H[N nbsms.
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tgm sbhm `oe`v`eubf.
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imfcw tgm mejm cl tgm ob`f pfbtm cr `o tgm hcst e`stbf pcrt`co
cl tgm ob`f ime. @ts nf`o`nbf prmsmotbt`co `s stmrmctypme boe
bsscn`btme w`tg b pb`oluf e`stbf t`p nbusme iy bo uoemrfy`oj
icoy mrcs`co wgmo v`subf`zme w`tg rbe`cjrbpgy. @o b rmv`mw
cl Ug`s fyt`n mllmnt hby im bttr`iutme tc tgm vmry rbp`e nchprmss`co nbusme iy
tgm tuhcr rbtgmr tgbo tc tuhcr `ovbs`co `tsmfl.75 Fcoj-tmrh
rbe`cfcj`n lcffcw up cl ^]DB `s rbrm. ^chm pbt`mots gbe b
nchpfmtm bismonm cl rmcss`l`nbt`co,72 wgmrmbs ctgmrs emh-
costrbtme schm pbrt`bf rmncost`tut`co cl tgm icoy emlmnt.7= @o
com nbsm rmpcrt, tgmrm wbs b spcotbomcus rmjrmss`co w`tg luff
rmcss`l`nbt`co.7< ]ftrbscocjrbpgy rmvmbfs b wmff-n`rnuh-
snr`ime, h`xme-mngc`n hbss. HY@ emhcostrbtms `otmrhme`btm
`otmos`ty co U2-wm`jtgme `hbjms boe h`xme s`jobf `otmos`ty
co U9-wm`jgtme `hbjms. B pmr`pgmrbf tg`o r`h cl ncotrbst
mogbonmhmot sujjmsts bo `olfbhhbtcry rmbnt`co `o tgm
surrcuoe`oj t`ssum.7:
Ugm e`bjocs`s cl e`stbf e`j`tbfdmrbtcbnbotgchb rmf̀ ms co tgm rbp`e jrcwtg cl tgm fms`co
boe tgm ncostbot pb`o `o bsscn`bt`co w`tg hme`nbf `hbj`oj
boe g`stcfcjy.
Ugm tgrmm hb`o e`llmrmot`bf e`bjocsms lcr ^]DB brm
mp`emrhc`e `hpfbotbt`co nyst, suiuojubf wbrt, boe ^NN.
^NN `s bfsc tgm hb`o g`stcfcj`n e`llmrmot`bf e`bjocs`s, wg`ng
rmhb`os e`ll`nuft4 tgm tuhcr `s lrmqumotfy e`bjocsme g`stc-
fcj`nbffy bs b ^NN, dmrbtcbnbotgchb typm. ^tcff rmpcrts tgbt
tgm g`stcfcj`nbf lmbturms gbvm tgm sbhm jmomrbf ncol`jurbt`co
L`j. 0 L`ircdmrbtchb br̀ s`oj lrch tgm hbtr`x boe e`ssmnt`oj tgm pfbtm (`otrbuojubf l`ircdmrbtchb).
L`j. 2; L`ircdmrbtchb cl tgm ob`f ime.
L`j. 22 Dcmomo tuhcrs `o b tuimrcus snfmrcs`s.
L`j. 29 E`stbf suiuojubf dmrbtcbnbotgchb.
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bs dmrbtcbnbotgchb mfsmwgmrm, iut tgmy tmoe tc im hcrm
vmrt`nbffy cr`motme boe tc mxg`i`t hcrm eysdmrbtct̀ n nmffs,
lmwmr omutrcpg`fs boe mcs`ocpg`fs, boe f`ttfm cr oc l`ircs`s bt
tgm`r ibsm.77 E`st̀ oju s̀g`oj dmrbtcbnbotgchb lrch wmff-
e`llmrmot`btme ^NN `s schmt`hms e`ll`nuft. Ymnmot mv`emonm
`oe`nbtms tgbt tgm ounfmbr lbntcr dbppb-I p=; suiuo`t boe
ncrtbnt`o hby im usmluf tc e`st`oju`sg imtwmmo tgmsm twc
ncoe`t`cos. Ictg tgm p=; suiuo`t boe ncrtbnt`o gbe g`jgmr fmvmfs cl mxprmss`co `o dmrbtcbnbotgchb tgbo `o ^NN. Ictg
wmrm fcnbf`zme tc tgm ibsbf nmff fbymr cl dmrbtcbnbotgchb,
wgmrmbs tgmy wmrm snbttmrme w`tgcut pcfbr`ty tgrcujgcut tgm
^NN fms`cos.70 Ugm mxprmss`co cl D`- bo bsscn`bt`co
w`tg ecrsbf ptmryj`uh,2;5,2;= coyngchyncs`s,2;< cr fcoj`tu-
e`obf hmfbocoyng`b.2;< Emrhbtcsncpy gmfps w`tg e`bjocs`s
iy emhcostrbt`oj huft`pfm pmrlcrbt`cos cl tgm ob`f pfbtm bt `ts
lrmm icremr. Ymnmotfy, rmsmbrngmrs rmpcrtme tgbt tgm bobfys`s
cl b ob`f nf`pp`oj `s b lbst boe h`o`hbffy `ovbs`vm hmtgce tc
bng`mvm tgm ncrrmnt e`bjocs`s cl coyngchbtr`nchb iy
e`llmrmot`bt̀ oj coyngchbtr`nchb lrch suiuojubf tuhcrs
boe mxnfue`oj luojbf `olmnt`co w`tg b pmr`ce`n bn`e-^ng`ll stb`o.2;: ]ftrbsco`n mxbh`obt`co bfsc smmhs prch s̀`oj. B
rmnmot stuey emhcostrbtme b gypmrmngc`n tuhcrbf fms̀ co
bllmnt`oj tgm hbtr`x zcom w`tg gypmrmngc`n f`ombr spcts boe
prcamnt`cos `otc tgm `otmrpfbtm spbnm.2;7 Hbjomt`n rmscobonm
`hbj`oj `s typ`nbf4 `t rmvmbfs b tuhcr tgbt `s mhmrj`oj lrch
tgm ob`f hbtr`x w`tg tgm sbhm s`jobf bs ocrhbf mp`tgmf`uh boe
w`tg prcnmssms tgbt mxtmoe `otc tgm tg`ndmome ob`f pfbtm.2;0
Ob`f bvufs`co nbo im e`bjocst`n bs `t mxpcsms b v`ffcus tuhcr
mhmrj`oj lrch tgm hbtr`x tgbt `s mvcnbt`vm cl b smb bomhcom4
tgm ob`f bppmbrs bs b tg`ndmome luoomf stcr`oj tgm l`fbhmotcus
e`j`tbt`cos cl tgm hbtr`x tgbt l`t `otc tgm gcfms cl tgm prcx`hbf
ob`f mxtrmh`ty (L`jurm 25). Ugcsm e`j`tbt`cos brm coyngc-jmo`n boe rmspcos`ifm lcr tgm tg`ndmo`oj cl tgm ob`f pfbtm.
Ugm`r fmojtg hby cnnbs`cobffy im bs sung tgbt nf`pp`oj cl tgm
lrmm mejm `oeunms ifmme`oj.22; Nf`o`nbf lmbturms brm ngbrbn-
tmr`st`n, iut coyngchyncs`s boe Icwmo e`smbsm222 sgcufe im
rufme cut.
Ugm surj`nbf rmhcvbf cl tgm tuhcr `s tgm cofy cpt`co, boe
tgm tuhcr sgcufe cofy im sgbvme. Imnbusm `t `s `hpcss`ifm tc
rmpfbnm tgm pfbtm (wg`ng `s bftmrme boe sgcufe uoemrjc
L`j. 2> Coyngchbtr ǹchb. Octm tgm swmff̀ oj cl tgm prcx`hbfob`f lcfe boe tgm xbotgcoyng`b.
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g`stcfcj`nbf mxbh`obt`co), `t hby im w`sm tc sf`em schm tuffm
jrbs uoemr tgm prcx`hbf ob`f lcfe boe smnurm `t w`tg twc
st`tngms. Ug`s w`ff bvc`e boy begmrmonm imtwmmo tgm vmotrbf
pbrt cl tgm prcx`hbf ob`f lcfe boe tgm hbtr`x, wg`ng ncufe
rmsuft `o ptmryj`uh. Bltmr > wmmds, tgm tuffm jrbs hby im
rmhcvme4 bt tgbt t`hm, tgm hbtr`x w`ff bfrmbey gbvm gmbfme
boe syotgms`zme schm dmrbt`o.52
G`stcfcjy cl tgm surj`nbf spmǹ hmo `s uo`qum1 tgm e`stbf zcom
`s ngbrbntmr z̀me iy huft`pfm‖jfcvm l`ojmr ‘ pbp`ffbry prcamnt`cos
ncvmrme iy b hbtr`x-typm mp`tgmf`uh tgbt `s emvc`e cl strbtuh
jrboufcsuh boe tgbt dmrbt`o`zms tgrcujg bo mcs`ocpg̀ f`n
dmrbtcjmocus zcom. Ugm prcx`hbf zcom, wg`ng ncrrmspcoes
w`tg tgm pmeuonfm, `s echm-sgbpme `o trbosvmrsm smnt`cos. @t `s
f`ome iy b pbp̀ ffchbtcus hbtr`x-typm mp t̀gmf`uh w`tg vmrt`nbffy
cr`motme emmp `ovbj`obt`cos `otc tgm strchb. Ugmsm `ovbj`ob-
t`cos surrcuoe cpt̀ nbffy mhpty nbv̀ t m̀s `o b ngbrbntmr s̀t ǹ
\-sgbpme ncol`jurbt`co. Ugm rmncjo t̀`co cl hbtr`x-typm mp`tgm-
f`uh w`tg \-sgbpme emprmss`cos `s nrun`bf tc hbdm tgm e`bjocs`s
cl coyngchbtr`nchb co lrbjhmotme cr `onchpfmtm spmn`hmos,wg`ng fbnd tgm ‖jfcvm l`ojmr ‘ pbp`ffbry prcamnt`cos.229
^upmrl`n`bf bnrbf l`irchyxchb (e`j`tbf l`irchyxchb)
^upmrl`n`bf bnrbf l`irchyxchb `s b rbrm, sfcw-jrcw`oj,
sclt-t`ssum tuhcr tgbt gbs b prme`fmnt`co lcr tgm suiuojubf
boe pmr`uojubf rmj`cos cl tgm l`ojmrs boe tcms `o beufts. 22>
Ugm nf`o`nbf prmsmotbt`co gbs oct immo luffy emtb`fme, imnbusm
tg s̀ ncoe`t̀ co `s hcstfy b g`stcfcj`nbf e`sncvmry. ^chm
rmpcrts hmot`co b echm-sgbpme, wmff-n`rnuhsnr`ime, wg`t`sg
tc p`od`sg l`rh tuhcr (schmt`hms w`tg b ncffbrmttm bt `ts ibsm)
f`lt`oj up tgm pfbtm, wg`ng `s ncvmrme w`tg vmry tg`o nrbndme
gypmrdmrbtcs`s (L`jurm 2=)4 `l tgm tuhcr `s fcnbtme emmpfy `o
tgm fbtmrbf ob`f lcfe, tgmrm w`ff im b swcffmo lcfe ncvmrme w`tg
ocrhbf sd`o.225,22= G`stcfcjy emhcostrbtms b wmff-n`rnuh-
snr`ime, uomonbpsufbtme tuhcr fcnbtme `o tgm emrh`s cr tgm
suinut̀ s, w t̀g cofy rbrm mxtmos`co `otc tgm icom. @t `s
nchpcsme cl stmffbtm boe sp`oefme nmffs mhimeeme `o b
hyxc`e hbtr`x, cltmo w`tg bnnmotubtme vbsnufbturm boe
`onrmbsme ouhimrs cl hbst nmffs. Ounfmbr btyp`b `s sf`jgt cr
bismot, boe h`tct`n l`jurms brm `olrmqumot. @hhuocg`stc-
ngmh`nbffy, 5.
NE00 boe mp`tgmf`bf hmhirbom bot`jmo (MHB) nbo bfsc im
lcnbffy pcs`t`vm.22 @t hby cnnur bt boy bjm eur`oj beuftgcce,
w`tg b pmbd `on`emonm imtwmmo tgm bjms cl =; boe ; Bfhcst com tg`re cl pbt`mots
w t̀g ^NN cl tgm ob`f bppbrbtus gbvm b g`stcry cl G[\-
bsscn b̀tme jmo`tbf e`smbsm (`m, jmo`tbf wbrts, eyspfbs b̀, cr
nbonmr cl tgm nmrv`x cr bocjmo`tbf rmj`co) cr b smxubf pbrtomr
w`tg sung b g`stcry. Ugm bvmrbjm t`hm imtwmmo tgm cosmt cl
tgm jmo`tbf e`smbsm boe tgm bppmbrbonm cl tgm ob`f tuhcr `s
bpprcx`hbtmfy 29 ymbrs. @t smmhs tgbt tgm r`sd cl emvmfcp`oj
L`j. 25 Bvufs`co rmvmbfs tgm v`ffcus tuhcr co tgm hbtr`x boe tgmluoomf-sgbpme pfbtm.
L`j. 2= ^upmrl`n`bf bnrbf l`irchyxchb. Nchpbrm tg`s w`tg tgm`hbjm sgcwo `o L`jurm 5.
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bo bjjrmss`vm cr huft`pfm lcrh cl G[\-bsscn`btme ^NN cl
tgm ob`f bppbrbtus `s oct ncrrmfbtme w t̀g tgm pbt̀ mot ‐s
`hhuo`ty stbtus. ^NNs cl tgm ob`f bppbrbtus, wgmtgmr tgmy
brm bsscn`btme w t̀g G[\ cr oct, gbvm b s`h f̀br rbtm cl
hmtbstbs`s cl 9% tc >%.295
Ugm nf`o`nbf prmsmotbt`co cl ^NN `s prctm`lcrh4 `t cltmo
bppmbrs bs b nf`o`nbffy h`sfmbe`oj ‖ imo`jo‘ fms`co, wg`ng
emfbys tgm e`bjocs`s.2>2
Ugm e`llmrmot`bf e`bjocs`s monch- pbssms vmrrunb vufjbr`s, coyngchyncs`s, suiuojubf mxcstc-
s`s, mp`emrhc`e nyst, ibntmr`bf pbrcoyng`b, l`ircdmrbtchb, boe
coyngchbtr`nchb. Ugm hbf̀ jobot prcnmss hby emvmfcp `o tgm
mp`tgmf`uh cl tgm pbrcoyng`uh cr lrch tgm ob`f ime.
^uiuojubf `ovcfvmhmot `s tgm hcst nchhco l`oe`oj. ^NN
hcstfy prmsmots w`tg coyngcfys`s, boe nf`pp`oj bwby cl tgm
emtbngme ob`f pfbtm sgcws pbrt`bf cr mxtmos`vm gypmrdmrbtcs`s
cl tgm ob`f ime cr mvmo b vmrruncus hbss (L`jurm 29 w`tg
mrytgmhb nbusme iy `olfbhhbt`co bs b rmsuft cl `olmnt`co.
L`ssurm cr ufnmrbt`co cl tgm fbtmrbf ob f̀ jrccvm, wg`ng `s
schmt`hms nrustme w`tg jrboufbt`co-f`dm t`ssum imombtg tgm
snbi, hby bfsc im cismrvme.>; [b`o `s uonchhco.292,2>>
^chm suiuojubf gypmrdmrbtcs`s hby im trmbngmrcus1 tgmrm
hby im fcoj`tue`obf mrytgrcoyng`b w`tg coyngcpbp`f-
fchb,2>5 l`ircdmrbtchb,:
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`oe`nbtme.>;,0>,292,2>>,25:,257 ^chm ocosurj`nbf trmbthmots
gbvm immo rmpcrtme, `onfue`oj `h`qu`hce nrmbh,250 =-
lfucrcurbn`f nrmbh252,2=; w t̀g cr w`tgcut pr`cr nurmttbjm,
pgctceyobh`n tgmrbpy,2=2,2=9 boe `otrb-brtmr`bf `olus`co w`tg
hmtgctrmxbtm.2=> Ocom cl tgmsm tmngo`qums, gcwmvmr, bffcws
lcr tgm g`stcfcj`n ncotrcfs cl tgm tuhcr hbrj`os. Ugmsm
sgcufe im ncos`emrme bs trmbthmot cpt`cos lcr spmn`bf nbsms,
wgmo surjmry `s oct lmbs`ifm.
\mrruncus nbrn`ochb
Ug`rtmmo nbsms cl vmrruncus nbrn`ochb `ovcfv`oj tgm ob`f
bppbrbtus gbvm immo rmpcrtme `o tgm f`tmrbturm. Ug`s `s b rbrm,
g`jgfy dmrbt`o`z`oj vbr`bot cl ^NN tgbt `s ngbrbntmr`zme iy
fcnbf bjjrmss`vmomss iut b fcw pctmot`bf lcr hmtbstbs`s. Ugm
pfbotbr lcrh `s bfsc docwo bs mp`tgmf`chb nuo`nufbtuh.2=5
Ugm nf`o`nbf prmsmotbt`co `s cltmo h`sfmbe`oj4 tg`s ncoe`t`co
cltmo bppmbrs bs b wbrty fms c̀o tgbt `onrmbsms `o s`zm w`tg t`hm.
Ugm ob`f imes cl tgm tguhi, tgm jrmbt tcmob`f, boe tgm l`ltg
tcmob`f brm tgm hcst nchhco fcnbt`cos. B nbsm `ovcfv`oj tgm
lcurtg l`ojmr wbs rmnmotfy rmpcrtme.2== Fcoj mvcfv`oj fms`cos
w`tg pbp`ffchbtcus e`j`tbt`cos brm qu`tm typ`nbf. Hcgs surjmry
cr mo ifcn mxn`s`co lcffcwme iy b luff-tg`ndomss jrblt 2== `s tgm
trmbthmot cl ngc`nm, iut, `o bevbonme nbsms, bhputbt`co hby
im hboebtcry. Com nbsm wbs sunnmssluffy trmbtme w`tg tgm
`otrb-brtmr`bf `olus`co cl hmtgctrmxbtm.2=<
Hmfbochb
Ob`f bppbrbtus hmfbochb (OBH) `s rbrm4 bnncre`oj tc
smvmrbf smr`ms, `t bnncuots lcr ;.27% tc 9.7% cl bff nutbomcus
hmfbochbs.2=:
Ugm mst̀ hbtme `oǹ emonm rmbngms ;.2 pmr 2;;,;;; pmcpfm pmr ymbr.2=7 Ugm rmfbt`vm `on`emonm cl OBH
bhcoj Blr`nbo boe Bs`bo `oe`v`eubfs `s hung g`jgmr tgbo
tgbt lcuoe bhcoj Nbunbs`bos1 bicut 9=% cl hmfbochbs brm
fcnbtme `o tgm ob`f bppbrbtus `o Abpbomsm boe Blr`nbo
Bhmr`nbos, iut tgm biscfutm `on`emonm cl OBH hby wmff
im s`h`fbr lcr bff rbn`bf jrcups.2=: Ugm bvmrbjm bjm cl cosmt `s
eur`oj tgm s`xtg boe smvmotg emnbems. OBH `s uousubf `o
ng`fermo, w`tg cofy 2> rmpcrtme nbsms tc ebtm.2=0 Ugm tguhi
boe tgm jrmbt tcmob f̀ brm hcst lrmqumotfy bllmntme,2
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nbo tgmrmlcrm smrvm bs b com-stmp surj`nbf trmbthmot lcr `o s`tu
cr h`o`hbffy `ovbs`vm hmfbochb, tgmrmiy erbhbt`nbffy
rmeun`oj tgm eurbt`co cl pcstcpmrbt`vm e`sbi`f`ty.
\br`cus mxn`s`cobf i`cpsy tmngo`qums gbvm immo emsnr`ime
tc mosurm g`stcfcj`nbf e`bjocs`s boe tc f`h`t tgm r`sd cl
pcstcpmrbt`vm eystrcpgy lcr b fms`co tgbt ncufe turo cut tc im
imo`jo.2:> @on`s`cobf i`cpsy `s oct rmnchhmoeme, imnbusm `t
ecms oct bffcw lcr tgm nchpfmtm g`stcfcj`nbf mxbh`obt`co cl tgm p`jhmotme fms`co.
@o >;% cl nbsms, OBH br s̀ms lrch tgm ob`f ime boe
prmsmots bs b oceufm tgbt hby im p`jhmotme, bo ufnmrbt`co
w`tg ifmme`oj, bo `scfbtme lcfe p`jhmotbt`co, bo uomxpfb`ome
hcocebntyf`n pbrcoyng`b, cr b pbrt`bf emstrunt`co cl tgm ob`f
pfbtm.2:5 Com sgcufe rmhmhimr tgbt bicut 9;% tc >;% cl
nbsms cl OBH brm bhmfboct`n.2=: Ug s̀ ncoe`t̀ co `s mvmo
hcrm trmbngmrcus wgmo `t hbo`lmsts bs b hcocebntyf`n
coyngcrrgmx`s.2:=
]olcrtuobtmfy, tgm e`bjocs`s cl OBH `s vmry cltmo emfbyme,
boe tg`s `s bsscn`btme w t̀g b pccr prcjocs`s. Ug`s emfby hby im
bttr`iutme tc pbt`mots wgc ec oct `o`t`bffy suspmnt tgm e`bjocs`s
cl nbonmr bt tgbt s`tm boe ncosuft tgm r̀ pgys`n`bos bt b fbtm stbjmcl e`smbsm, wgmo swmff`oj, ufnmrbt`co, ccz`oj cr ifmme`oj
cnnur. Ugmsm nf`o`nbf lmbturms brm bfrmbey bsscn`btme w`tg b
tg`nd Irmsfcw `oemx.2:< Cofy com tg`re cl pbt`mots w t̀g
fcoj`tue`obf hmfbocoyng`b smmd hme`nbf bev`nm2=: (L`jurm 9;).
Ugm cvmrbff bnnurbny cl emrhbtcfcj s̀ts w`tg rmjbre tc tgm
e`bjocs s̀ cl ob`f hbtr`x hmfbochb prmsmot̀ oj bs b fcoj̀ tuè obf
hmfbocoyng`b rmhb`os fcw4 `t rbojme lrch 5
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surv`vbf imoml`ts gbvm immo emhcostrbtme. Mbrfy e`bjocs`s
boe mxn`s`co cl tgm tuhcr `s tgm cofy trmbthmot tgbt gbs immo
emhcostrbtme tc `onrmbsm surv`vbf.2=:
Ibsbf nmff nbrn`ochb
Ibsbf nmff nbrn`ochb (INN) `s tgm fmbst nchhco bt tgm
ob`f bppbrbtus4 brcuoe 9; nbsms gbvm immo rmpcrtme `o tgmMojf s̀g f`tmrbturm. Ugm bvmrbjm bjm cl e`bjocs`s `s cr fcoj`tue`obf hmfbocoyng`b.209,205 B nbsm cl INN
emvmfcpme `o b rbe`cemrhbt`t`s cl tgm prcx`hbf ob`f lcfe cl b
pufhbocfcj`st 20=4 boctgmr cnnurrme `o b wcrdmr wgc embft
w`tg bzc p`jhmot.20< Ugm nfbss ǹ nf`o`nbf INN prmsmotbt`co
cismrvme co tgm sd`o―w`tg oceufms, b pmbrfy icremr nrust`oj
―wbs moncuotmrme `o cofy b h`ocr t̀y cl nbsms. Hcgs
surjmry wbs tgm l`rst-ngc`nm trmbthmot `o tgm vbst hbacr`ty cl
nbsms, w`tg mxnmffmot cutnchms.20: ^chm pbt̀ mots bfsc
uoemrwmot mxn`s`co boe/cr bhputbt`co.207
Ymlmrmonms
2. [`rbnn`o` IH, Imffbv`stb ^, H`sn`bf` N, mt bf. [mr`uojubf boe suiuojubf
pycjmo`n jrboufchb. Ir A Emrhbtcf. 9;2;421052-0=>.
9. [`rbnǹ o` IH, @cr̀ zzc H. Eruj rmbnt`cos bllmnt̀ oj tgm ob`f uo t̀1
e`bjocs`s boe hbobjmhmot. Emrhbtcf Nf`o. 9;;:49=192=„992, v``.
>. Nbhpimff A[, Jrmd`o YN, Mff`s NO, mt bf. Ymt`oc`e tgmrbpy `s
bsscǹ btme w`tg mxnmss jrboufbt`co t`ssum rmspcosms. A Bh Bnbe
Emrhbtcf. 207>401:;7-:2>.
5. Umdomtz s̀ B, @cboo`ems E, \bdbf` J, mt bf. [ycjmo`n jrboufchbs
lcffcw`oj tcp`nbf bppf̀ nbt`co cl trmt`oc`o. A Mur Bnbe Emrhbtcf
\momrmcf. 9;;54271>>:->>0.
=. Ebwd`os HB, Nfbrd BY, Lmfehbo ^Y. [ycjmo`n jrboufchb-f`dm
fms`co bsscn`btme w`tg tcp ǹbf tbzbrctmom tgmrbpy. A Bh Bnbe
Emrhbtcf. 9;;;45>(2 [t 2)12=5-2==.
>7(95)12::>->>:.
2=. Lrm`hbo B, Icujbo`h O, C‐Ir`mo MB. Nbsm rmpcrts1 h`tczbotrcom-
`oeunme coyngcfys`s bsscn`btme w`tg suiuojubf bisnmssms, pbrcoyng`b,
boe pycjmo`n jrboufchb. A Erujs Emrhbtcf. 9;;=45150;-509.
291790-7>;.2:. Zcff`ob ]. Huft`pfm mrupt`vm pmr`uojubf pycjmo`n jrboufchbs eur`oj
bot`-NE9; hcocnfcobf bot`icey tgmrbpy lcr rgmuhbtc è brtgr`t`s.
A Emrhbtcf Nbsm Ymp. 9;2;45155-5.
20. Y`ngmrt I. Lr̀ nt`cobf pycjmo`njrboufchb cltgm ob`f ime. Emrhbtcfcjy
(Ibsmf). 9;;249;917;-72.
9;. Ncfvmr JI. Coyngct`ffchbo`b. Ir A Emrhbtcf. 207:422:1>0:->00.
92. Ucst` B, [`rbnn`o` IH, Nbhbngc-Hbrt òmz L. Coyngchbems`s boe
pycjmo`n jrboufchb lcffcw`oj nbst `hhci`f`zbt`co. Brng Emrhbtcf.
9;;242>:19>2-9>9.
99. Ucst` B, Ibrbo Y, [mfusc BH, mt bf. Ymlfmx syhpbtgmt`n eystrcpgy
w`tg prch`omot `ovcfvmhmot cl tgm ob f̀ bppbrbtus. A Bh Bnbe
Emrhbtcf. 200>490(= [t 9)47:-9>7.
95. ^`rbjusb H, ^ngmp`s N, Ncsmot`oc L@, mt bf. Ob`f pbtgcfcjy `o pbt`mots
w`tg gmh`pfmj`b. Ir A Emrhbtcf. 9;;242551==:-=. Hbrngbe`mr B, Ncgmo H, Fmjrm Y. ^uiuojubf jfchus tuhcrs cl tgm
l`ojmrs1 uftrbscuoe e`bjocs`s. Ng`r Hb`o. 9;;-9:.
>=. Abifco H, Gcrcw`tz B, Imrostm`o EB. Hbjomt`n rmscobonm `hbj`oj cl
b jfchus tuhcr cl tgm l`ojmrt`p. A Gboe ^urj Bh. 200;42=1=;:-=;0.
>:. Erbpà AF, @ey-[mrmtt` @, Jcmtthboo ^, mt bf. ^tboebre boe g`jg
rmscfut`co hbjomt`n rmscobonm `hbj`oj cl jfchus tuhcrs cl tcms boe
l`ojmrt`ps. A Bh Bnbe Emrhbtcf. 200=1==;-===.
>7. Y`ngmrt I, Ibjgb`m H. Hme`nbf `hbj`oj boe HY@ `o ob`f e`scremrs1
rmpcrt cl 220 nbsms boe rmv`mw. Emrhbtcf Ugmr (Gm`emfi). 9;;942=1
2=0-20. Jboeg` A, Pboj ^^, Gure A. Ugm bobtch`n fcnbt`co cl e`j`tbf jfchus
tuhcr rmnurrmonms. A Gboe ^urj Bh. 9;2;4>=1070
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52. e` Ng`bnng`c O, Y`ngmrt I, Gbomdm M. ^urjmry cl tgm hbtr`x. @o1
Y`ngmrt I, e` Ng`bnng`c O, Gbomdm M, mes. Ob`f ^urjmry. Fcoeco1
@olcrhb4 9;224 p. 2;>-2>9.
59. Fmm E-Z, Pboj A-G, Ngboj ^, mt bf. Nf`o`nbf boe pbtgcfcj`nbf
ngbrbntmr`st`ns cl mxtrbe`j`tbf boe e`j`tbf jfchus tuhcurs1 b rmtrcspmn-
t`vm nchpbrbt v̀m stuey. A Mur Bnbe Emrhbtcf \momrmcf. 9;2249=1
2>09-2>0:.
5>. \bs`sgt I, Zbtsco GD, Acsmpg M, mt bf. E`j`tbf jfchus tuhcrs1 b 90-
ymbr mxpmr`monm w`tg b fbtmrbf suipmr`cstmbf bpprcbng. [fbst Ymncostr
^urj. 9;;542251257 nbsms). Boo Emrhbtcf \momrmcf.
200:429519>>-9>. Gcmgo AJ, Ncfmttb N. ^uiuojubf mxcstcs`s cl tgm l`ojmrs. A Gboe ^urj
Bh. 200942:15
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0>. Em Imrdmr E. Gcfe co tgm bhputbt`co. Ir A Emrhbtcf. 9;;>42571
2;::-2;:7.
05. Ibrbo Y, D`ot B. Coyngchbtr`xchb. L`fbhmotcus tultme tuhcur `o tgm
hbtr`x cl b luoomf-sgbpme ob`f1 b omw mot`ty (rmpcrt cl tgrmm nbsms). Ir
A Emrhbtcf. 2009429;:->22.0:. Ucst` B, [`rbnn`o` IH, Nbfemrcò C, mt bf. Coyngchbtr`nchb1 rmpcrt cl
tgrmm nbsms, `onfue`oj tgm l`rst rmncjo`zme `o b ncfcrme hbo. Mur A
Emrhbtcf. 9;;;42;1= nbsms. Ir A Emrhbtcf.
9;;:42=-7==.
29>. Bfbh H, Nbfewmff AI, Mf`mzr` PE. Guhbo pbp`ffchbv`rus-bsscn`btme
e`j`tbf squbhcus nmff nbrn`ochb1 f`tmrbturm rmv`mw boe rmpcrt cl 92
omw nbsms. A Bh Bnbe Emrhbtcf. 9;;>4571>7=->0>.
295. Y`eemf N, Ybsg`e Y, Ugchbs \. ]ojubf boe pmr`uojubf guhbo
pbp`ffchbv`rus-bsscn`btme squbhcus nmff nbrn`ochb1 b rmv`mw. A Bh
Bnbe Emrhbtcf. 9;224.
29=. Ibrbo YF, Jcrhfmy EM. [cfyebntyfcus Icwmo‐s e`smbsm cl tgm ob`f. A
Bh Bnbe Emrhbtcf. 207:42:(9 [t 2)19;2-9;5.
29>;.
297. ^g`h`zu B, Ubhurb B, Bim H, mt bf. Emtmnt`co cl guhbo
pbp`ffchbv`rus typm =< `o Icwmo‐s e`smbsm `ovcfv`oj tgm ob`f hbtr`x.
Ir A Emrhbtcf. 9;;742=7129:>-29:0.
290. Lcrsfuoe C, Ocre`o [, Boemrssco D, mt bf. EOB bobfys`s `oe`nbtms
pbt`mot-spmn`l`n guhbo pbp`ffchbv`rus typm 2< strb`os `o Icwmo‐s
e`smbsm co l`ojmrs boe `o brng`vbf sbhpfms lrch jmo`tbf eyspfbs`b. Ir A
Emrhbtcf. 200:42>5. Ibrbo Y, [mrr`o N. Fcoj`tue`obf mrytgrcoyng̀ b w`tg e`stbf suiuojubf
dmrbtcs`s1 coyngcpbp`ffchb cl tgm ob`f ime boe Icwmo‐s e`smbsm. Ir A
Emrhbtcf. 9;;;425>12>9-2>=.
2>=. Ibrbo Y, ^`hco N. Fcoj`tue òbf hmfbocoyng b̀1 b syhptch cl
Icwmo‐s e`smbsm. A Bh Bnbe Emrhbtcf. 207742712>=0-2>0150;-50>.
2>:. Ibrbo Y, M`nghboo B. Fcoj̀ tue`obf hmfbocoyng`b bsscn`btme w`tg
Icwmo‐s e`smbsm1 twc omw nbsms. Emrhbtcfcjy (Ibsmf). 200>427;=->;0. Tqu`z 90;19;5-9;0.
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259. Boerà A, ^bss ], Ugmuo`s B. E`smbsms cl tgm ob`f. @o1 Nbfcoaà M, Irmoo
U, Fbzbr B, mes. HnDmm‐s [btgcfcjy cl tgm ^d`o. Fcoeco1 Mfsmv`mr4
9;29. p. 2;re FY, Ycsmo U, Usngmo AB. ^uiuojubf squbhcus nmff
nbrn`ochb. A Bh Bnbe Emrhbtcf. 2075422(5 [t 9)1:>=-:>7.25;(9 [t 2)1927-992.
25:. Qb`bn HO, Zm`ss M. Hcgs h`nrcjrbpg`n surjmry cl tgm ob`f uo`t boe
squbhcus nmff nbrn`ochb. Emrhbtcf ^urj. 9;;249:195;(9 [t 2)1922-92>.
2=;. ^turh GH. Icwmo‐s e`smbsm boe =-lfucrcurbn`f. A Bh Bnbe Emrhbtcf.
20:0421=2>-=99.
2=2. Ubo I, ^`onfb`r Y, Lcfmy [. [gctceyobh`n tgmrbpy lcr suiuojubfIcwmo‐s e`smbsm. Bustrbfbs A Emrhbtcf. 9;;545=12:9-2:5.
2=9. ]shbò O, ^tbifms J@, Umflmr OY, mt bf. ^uiuojubf Icwmo‐s e`smbsm
trmbtme iy tcp`nbf bh`ocfmvuf`o`n bn`e-pgctceyobh`n tgmrbpy. A Bh
Bnbe Emrhbtcf. 9;;=4=>(= ^uppf 2)1^9:>-^9:. ^gmmo P-^, ^gmmo H-N, ^gmu G-H, mt bf. ^qubhcus nmff nbrn`ochb cl
tgm i`j tcm sunnmssluffy trmbtme iy `otrb-brtmr̀ bf `olus`co w`tg
hmtgctrmxbtm. Emrhbtcf ^urj. 9;;>4901079-07>.
2=5. \bo Jmmrtruyemo A[, Cfmhbos N, Fbpcrtm H, mt bf. \mrruncus
nbrn`ochb cl tgm ob`f ime. Lcct Bodfm @ot. 20074201>9:->97.
2==. Hbtcsc B, Amff`omd O, Umfboj JG. \mrruncus nbrǹ ochb cl tgm ob`f
uo`t. Bh A Emrhbtcpbtgcf. 9;294>51m2;X.
2=7. Hbrt`o EM, Mojf̀ sg AN, Jc`tz YA. ^uiuojubf hbf`jobot hmfbochb.
A Gboe ^urj Bh.. 9;224>.
22120;9-2029.
2>.
2:2. G`rbtb ^G, Pbhbeb ^, Mocd`gbrb HP, mt bf. [bttmros cl ob`f hbtr`x boe
ime cl fcoj`tue`obf hmfbocoyng`b iy `otrbcpmrbt`vm emrhbtcsncpy. A Bh Bnbe Emrhbtcf. 9;224;>.
2:9. Emibri`mux ^, Gcspce \, Empbmpm F, mt bf. [mr`cpmrbt`vm ncolcnbf
h`nrcsncpy cl tgm ob`f hbtr`x `o tgm hbobjmhmot cl `o s`tu cr
h`o`hbffy `ovbs`vm suiuojubf hmfbochbs. Ir A Emrhbtcf. 9;2942. Amff`omd O. Ob`f hbtr̀ x i`cpsy cl fcoj`tue`obf hmfbocoyng`b1
e`bjocst`n bfjcr`tgh `onfue`oj tgm hbtr`x sgbvm i`cpsy. A Bh Bnbe
Emrhbtcf. 9;;:4=-72;.
2:5. Ucst` B, [`rbnn`o` IH, em Lbr`bs EN. Embf òj w`tg hmfbocoyng`b.
^mh`o Nutbo Hme ^urj. 9;;0497150-=5.
2:=. Boerà A, Hcufcojumt @, Jcmtthboo-Icovbffct ^. @o s`tu bhmfboct ǹ
hmfbochb cl tgm ob`f uo`t h`h`nd`oj f`ngmo pfbous1 rmpcrt cl > nbsms.
Brng Emrhbtcf. 9;2;4257:.
2:7. L`ofmy >re YD, Er s̀ncff EF, Ifuhmosco FM, mt bf. ^uiuojubf
hmfbochb1 bo m`jgtmmo-ymbr rmv`mw. ^urjmry. 2005422-2:=.
272. Ngcw ZUG, Igbt Z, Hbjeui ^, mt bf. @o s`tu suiuojubf hmfbochb1
e`j`t sbfvbj`oj nfmbrbonm. A [fbst Ymncostr Bmstgmt ^urj. 9;294
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209. Lcrhbo ^I, Lmrr`ojmr UN, Jbrrmtt BI. Ibsbf nmff nbrn`ochb cl tgm ob`f
uo`t. A Bh Bnbe Emrhbtcf. 9;;:4=. ^gbg E, Fmcpcfe J, ^cwemo A. Ibsbf nmff nbrn`ochb hbsqumrbe`oj bs
gbi`t t`n. Nf`o Mxp Emrhbtcf. 9;224>01>0:->07.
20=. ^mrrboc-Crtmjb ^, Lmroâoemz-Bojmf @, Eufbotc-Nbhpcs M, mt bf. Ibsbf
nmff nbrn`ochb br`s`oj `o prclmss`cobf rbe`cemrhbt`t`s cl tgm ob`f. Ir A
Emrhbtcf. 9;;9425:1