![Page 1: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/1.jpg)
2009 H1N1 Influenza in Minnesota Epidemiology
Infectious Disease Epidemiology, Prevention and Control Division PO Box 64975 St. Paul, MN 55164-0975
![Page 2: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/2.jpg)
0
25
50
75
100
125
150
175
200
225
250
275
300
325
350
375
400
425
450
4 0 4 3 4 6 4 9 52 2 5 8 11 14 17 2 0 2 3 2 6 2 9 3 2 3 5 3 8 4 1 4 4 4 7 50 1 4 7 10 13 16
Week of Specimen Collection
Num
ber o
f Hos
pita
lizat
ions
A/B (rapid test only)
B (rapid test only)
A (rapid test only)
Seasonal B
Untypeable A (likely 2009H1N1)2009 H1N1
Seasonal A
2008-2009 Influenza SeasonOctober 1, 2008 –
April 30, 2009
2009-2010 Influenza SeasonSeptember 1, 2009 –
April, 2010
Spring Influenza SurveillanceMay 1, 2009 –
August 31, 2009
1st
H1N1hospitalized case
Number of Hospitalized Cases of Influenza
by Influenza Type, Minnesota, October 2008 –
April 2010
![Page 3: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/3.jpg)
Number of Hospitalized PCR-confirmed 2009 H1N1 Influenza Cases, Minnesota, April 2009 –
April 2010
0
50
100
150
200
250
300
350
400
15 17 19 21 23 25 27 29 31 33 35 37 39 41 43 45 47 49 51 1 3 5 7 9 11 13 15 17
Week of Specimen Collection
Num
ber o
f Hos
pita
lizat
ions
Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb
![Page 4: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/4.jpg)
0
5
10
15
20
25
30
35
40
18 20 22 24 26 28 30 32 34 36 38 40 42 44 46 48 50 52 2 4 6 8 0 12 14 16
Week of Specimen Collection
Hos
pita
lizat
ions
per
100
,000
Per
sons
Cumulative Incidence of Hospitalized PCR-confirmed 2009 H1N1 Influenza Cases, Minnesota, April 2009 -
April 2010
![Page 5: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/5.jpg)
0
1
2
3
4
5
6
7
8
9
10
35 37 39 41 43 45 47 49 51 1 3 5 7 9 11 13 15 17 19 21 23 25 27 29 31 33 35
Week of Clinic Visit
% o
f Out
patie
nt V
isits
for
ILI
07-08 Season 08-09 Season 09-10 Season
Percentage of Outpatient Visits for ILI*, Sentinel Surveillance Sites by Season, Minnesota,
September 2007 –
April 2010
*Influenza-like Illness
Spring Wave
2009
Fall Wave
2009
Normal Flu Surveillance October 1 –
April 30
![Page 6: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/6.jpg)
Number and Percentage of Schools Reporting Outbreaks of ILI*, Minnesota, September 2009 –
April 2010
0
50
100
150
200
250
300
350
35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Week of Outbreak
Num
ber o
f Sch
ools
0%
5%
10%
15%
20%
25%
Number of Schools Reporting ILI
Percent of Eligible Schools Reporting ILI
*Influenza-like Illness
![Page 7: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/7.jpg)
Number and Percentage of Culture-Confirmed Influenza Specimens, Minnesota Virology
Laboratories, September 2007 –
April 2010
0
25
50
75
100
125
150
175
200
35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Week of Specimen Collection
Num
ber o
f Pos
itive
Cul
ture
Tes
ts
0
10
20
30
40
50
60
70
80
90
100
% o
f Pos
itive
Cul
ture
Tes
ts
Flu A/B+Flu B+Flu A+2007-2008 % +2008-2009 % +2009-2010 % +
![Page 8: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/8.jpg)
Number and Percentage of Positive Influenza Rapid Test Results, Minnesota Rapid Testing Sites,
September 2007 –
April 2010
0
250
500
750
1000
1250
1500
35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Week of Specimen Collection
Num
ber o
f Pos
itive
Rap
id T
ests
0
10
20
30
40
50
60
70
80
90
100
% o
f Pos
itive
Rap
id T
ests
Flu B+Flu A/B+Flu A+2007-2008 % +2008-2009 % +2009-2010 % +
![Page 9: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/9.jpg)
Circulating Respiratory Viruses, Laboratory Influenza Surveillance Program, Minnesota, October 2009 –
April 2010
0
20
40
60
80
100
120
140
160
180
200
40 42 44 46 48 50 52 2 4 6 8 10 12 14 16 18Week of Submission
Num
ber o
f Pos
itive
s
Adenovirus Enterovirus
Influenza A Influenza B
Human Metapneumovirus Parainfluenza – 1
Parainfluenza – 2 Parainfluenza – 3
Parainfluenza – 4 Rhinovirus
RSV
![Page 10: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/10.jpg)
0
50
100
150
200
250
300
350
400
450
500
0-4 5-18 19-24 25-49 50-64 65+
Age Group (yrs.)
Num
ber o
f Hos
pita
lizat
ions
0
20
40
60
80
100
120
Hos
pita
lizat
ions
per
100
,000
Per
sons
Number of Hospitalizations
Hospitalizations per 100,000 Persons
Number and Incidence of Hospitalized PCR- confirmed 2009 H1N1 Influenza by Age Group,
Minnesota, April 2009 –
April 2010
![Page 11: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/11.jpg)
Number and Incidence of Hospitalized PCR-confirmed 2009 H1N1 Influenza Cases by Race/Ethnicity,
Minnesota, April 2009 –
April 2010
Number of Cases Incidence per 100,000
White Black AsianHispanicNative American
43.2
73.9
68.0
26.2
104.2
1,179
45
83
140
259
![Page 12: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/12.jpg)
White
Black
Hispanic
Unknown
Asian
Native American
Multi Race
White
Black
Hispanic
Asian
UnknownMulti RaceNative
American
Spring Wave Fall Wave
Proportion of Hospitalized PCR-confirmed 2009 H1N1 Influenza Cases by Race/Ethnicity,
Minnesota, April 2009 –
April 2010
![Page 13: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/13.jpg)
Median Age of Hospitalized PCR-confirmed 2009 H1N1 Influenza Cases by Race/Ethnicity,
Minnesota, April 2009 –
April 2010
Race/Ethnicity Spring Wave Fall Wave
White 16.9 yrs. 30.0 yrs.
Black 12.3 yrs. 20.3 yrs.
Hispanic 5.3 yrs. 8.4 yrs.
Asian 5.4 yrs. 11.7 yrs.
Native American 48.2 yrs. 36.3 yrs.
All Races 11.1 yrs. 26.8 yrs.
![Page 14: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/14.jpg)
Incidence of Hospitalized PCR-confirmed 2009 H1N1 Influenza by Week, Minnesota, April 2009 –
April 2010
0
1
2
3
4
5
6
7
8
9
10
18 20 22 24 26 28 30 32 34 36 38 40 42 44 46 48 50 52 2 4 6 8 10 12 14 16
Week of Specimen Collection
Hos
pita
lizat
ions
per
100
,000
Per
sons
7-County Minneapolis-St. Paul MetroGreater Minnesota
Smoothed lines
“Spring Wave”
“Fall Wave”
![Page 15: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/15.jpg)
Marti
nFaribaul
t
Olmste
dDodg
eSteel
e
Hennepi
n
t
Tod
d
Dougla
sGran
t
71
Northwest18
West Central
57
Southeast156South
Central92
Central 280
Southwest 67
Northeast 129
Metro 1025
Number of Hospitalized PCR-confirmed 2009 H1N1 Cases by District of Residence, April 2009 –
April 2010
![Page 16: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/16.jpg)
Incidence of Hospitalized PCR-confirmed 2009 H1N1 Influenza by District of Residence,
Minnesota, April 2009 –
April 2010
11.7
40.2
24.9
39.136.5
32.1 30.6 32.1
0
10
20
30
40
50
Northwest
Northeas
tWest C
entral
Centra
l
Metro
South Centra
lSouthwest
SoutheastHos
pita
lizat
ions
per
100
,000
Per
sons
![Page 17: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/17.jpg)
Incidence of Hospitalized PCR-confirmed 2009 H1N1 Influenza by District of Residence and Wave,
Minnesota, April 2009 –
April 2010
0
10
20
30
40
50
Northwes
t
Northeas
tWest
Centra
l
Central
Metro
South C
entra
l
Southwest
Southeas
tH
ospi
taliz
atio
ns p
er 1
00,0
00 P
erso
ns
SpringFall
![Page 18: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/18.jpg)
Hospitalized PCR-confirmed 2009 H1N1 Influenza Cases by Age Group and Presence of Underlying Medical
Conditions, Minnesota, April 2009 –
April 2010
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%
Pediatric
Adult
Percent of Cases
Without Underlying Medical Condition
With Underlying Medical Condition(s)
![Page 19: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/19.jpg)
Underlying Medical Conditions of Hospitalized PCR- confirmed 2009 H1N1 Influenza Adult (≥
18 yrs.) Cases,
Minnesota, April 2009 –
April 2010
Underlying Medical Condition Total PercentAsthma 328 32%
Chronic Metabolic Disease 288 28%
Chronic Lung Disease 201 20%
Chronic Cardiovascular Disease 225 22%
Immunosuppressive Condition 108 11%
Cognitive Dysfunction 54 5%
Neuromuscular Disorder 62 6%
Cystic Fibrosis 7 1%
Chronic Renal Disease 92 9%
Cancer 30 3%
![Page 20: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/20.jpg)
Underlying Medical Conditions of Hospitalized PCR- confirmed 2009 H1N1 Influenza Pediatric (<18 yrs.) Cases,
Minnesota, April 2009 –
April 2010
Underlying Medical Conditions Total PercentAsthma 228 28%
Chronic Metabolic Disease 26 3%
Chronic Lung Disease 30 4%
Chronic Cardiovascular Disease 24 3%
Immunosuppressive Condition 32 4%
Developmental Delay 65 8%
Neuromuscular Disorder 37 5%
Cystic Fibrosis 2 <1%
Seizure Disorder 39 5%
![Page 21: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/21.jpg)
Proportion of Hospitalized PCR-confirmed 2009 H1N1 Influenza Cases Admitted to ICU by Age Group and Presence of Underlying Medical
Conditions, Minnesota, April 2009 –
April 2010
0%
10%
20%
30%
40%
50%
Pediatric Adult
% o
f Cas
es A
dmitt
ed to
ICU
Without Underlying Medical Condition
With Underlying Medical Condition(s)
19% All Cases
![Page 22: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/22.jpg)
0%
10%
20%
30%
40%
50%
Pediatric Adult
% o
f Cas
es R
equi
ring
Mec
hani
cal V
entil
atio
n Without Underlying Medical Condition
With Underlying Medical Condition(s)
Proportion of Hospitalized PCR-confirmed 2009 H1N1 Influenza Cases Requiring Mechanical Ventilation by Age Group and Presence of Underlying Medical Conditions,
Minnesota, April 2009 –
April 2010
10% All Cases
![Page 23: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/23.jpg)
0%
10%
20%
30%
40%
50%
Pediatric Adult
% o
f Cas
es w
ith P
neum
onia
Without Underlying Medical Condition With Underlying Medical Condition(s)
Proportion of Hospitalized PCR-confirmed 2009 H1N1 Influenza Cases Diagnosed with Pneumonia by Age Group and Presence of
Underlying Medical Conditions,
Minnesota, April 2009 –
April 2010
37% All Cases
![Page 24: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/24.jpg)
0%
2%
4%
6%
8%
10%
Pediatric Adult
% o
f Cas
es w
ith B
acte
rial C
o-In
fect
ion
Without Underlying Medical Condition
With Underlying Medical Condition(s)
Proportion of Hospitalized PCR-confirmed 2009 H1N1 Influenza Cases with Bacterial Co-Infection* by Age Group and Presence of Underlying
Medical Conditions, Minnesota, April 2009 –
April 2010
1.6% All Cases
*Cultural confirmation of a bacterial pathogen from sterile site
within 3 days of admission.
![Page 25: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/25.jpg)
Number and Percentage of Female Hospitalized PCR- confirmed 2009 H1N1 Influenza Cases Ages 13-49 Who
Were Pregnant, Minnesota, April 2009 –
April 2010
Spring Wave Fall Wave TotalFemales 13-49 Yrs. n=54 n=329 n=383
Pregnant Cases 20 (37%) 46 (14%) 66 (17%)
![Page 26: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/26.jpg)
Hospitalized PCR-confirmed 2009 H1N1 Influenza Cases in Minnesota: Summary
From April 1, 2009 to April 30, 2010: 1,824 hospitalized PCR-
confirmed 2009 H1N1 Influenza cases; 1,564 since September 1, 2009
– In Spring wave:• Median age, 11.8 years• 17% in ICU• 81% Cases from Metro Area
– In Fall wave:• Median age, 26.5 years• 20% in ICU• 52% Cases from Metro Area
– Pregnancy among hospitalized women 13 -
49 years of age:• 17% (of 384)
![Page 27: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/27.jpg)
Number of Deaths Related to Influenza A, Minnesota, April 2009 –
April 2010
67 Deaths Related to Influenza A
• 63 2009 H1N1 Influenza
• 4 Influenza A, Not Subtyped
• 55 Hospitalized
• 12 Non-hospitalized
![Page 28: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/28.jpg)
Deaths Related to Influenza A by Wave and Age Group, Minnesota, April 2009 –
April 2010
Age Group (yrs.) Spring Fall Total
<18 2 6 8
18-64 1 45 46
65+ 1 12 13
Total Deaths 4 63 67
![Page 29: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/29.jpg)
Deaths Related to Influenza A by Race/Ethnicity, Minnesota, April 2009 –
April 2010
(63=2009 H1N1; 4=unspecified Influenza A)
Native American
Black
Hispanic
Asian
White
![Page 30: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/30.jpg)
Influenza A Deaths in Minnesota by Week of Collection, (N=67)Minnesota, April 2009 –
April 2010
South Central
Northwest
Northeast
Metro
Week of Collection
Num
ber o
f Dea
ths
24 2523 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47
Jun Jul Aug Sep Oct DecNov
1
2
3
4
5
6
48 49 50
7
8
9
10
11
12
West Central
Central
Southwest
Southeast
51 52 1 9
MarJan
13
2
![Page 31: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/31.jpg)
Influenza A Crude Death Rates by District of Residence, Minnesota, April 2009 –
April 2010
(63=2009 H1N1; 4=unspecified Influenza A)
District Deaths n=67Crude Death Rate per
100,000 Persons
Northwest 2 1.34
Northeast 11 3.43
West Central 2 0.77
Central 7 0.99
Metro* 30 1.07
South Central 5 1.93
Southwest 2 0.91
Southeast 8 1.65
*All 4 deaths in spring wave occurred in Metro district residents
![Page 32: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/32.jpg)
Deaths Related to Influenza A by Age Group and Presence of Underlying Medical Condition(s), Minnesota, April 2009 –
April 2010
(63=2009 H1N1; 4=unspecified Influenza A)
Age Group (yrs.) Total Deaths % With Underlying Medical Condition(s)
<18 8 75.0%
18-64 46 84.8%
≥65 13 92.3%
All Ages 67 87.7%
![Page 33: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/33.jpg)
Underlying Medical Conditions among Deaths Related to Influenza A, Minnesota, April 2009 –
April 2010
(63=2009 H1N1; 4=unspecified Influenza A)
Underlying Medical Condition Total Percent
Obesity 30 46.9%
Chronic Cardiovascular Disease 27 42.2%
Chronic Metabolic Disease 21 32.8%
Immunosuppressive Condition 15 23.4%
Chronic Lung Disease 11 17.2%
Renal Disease 9 14.1%
Neuromuscular Disorder 7 10.9%
History of Lymphoma/Leukemia 6 9.4%
Cognitive Dysfunction 6 9.4%
Asthma 6 9.4%
Cancer Diagnosis in last 12 months 4 6.3%
Seizure Disorder 4 6.3%
Pregnant 0 0.0%
![Page 34: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/34.jpg)
BMI of Adult Deaths Related to Influenza A, Minnesota, April 2009 –
April 2010
(55=2009 H1N1; 4=unspecified Influenza A)
17%
24%
5%
20%
12%
22%
Underweight:<18.5Normal:18.5–24.9Overweight:25.0–29.9Obese:30.0–39.9Morbidly Obese:≥40Unknown
![Page 35: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/35.jpg)
Clinical Outcomes of Deaths Related to Influenza
A by Age Group, Minnesota, April 2009 –
April 2010
(63=2009 H1N1; 4=unspecified Influenza A)
Clinical OutcomePediatric <18 yrs.
n=8Adult 18+ yrs.
n=59
Hospitalized 5 (62.5%) 50 (84.7%)
ICU 5 (62.5%) 46 (78.0%)
Mechanical Ventilation 6 (75%) 40 (67.8%)
ARDS 1 (12.5%) 16 (27.1%)
Pneumonia 5 (62.5%) 48 (81.4%)Viral 0 10 (16.9%)
Bacterial 1 (12.5%) 3 (5.5%)Both 0 3 (5.5%)
![Page 36: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/36.jpg)
Bacterial Co-Infections in Deaths Related to Influenza A, Minnesota,
April 2009 –
April 2010 (63=2009 H1N1; 4=unspecified Influenza A)
Sterile Non-sterile* Combined
Total (%) Total (%) Total (%)Persons with Bacterial Co-infection(s) 10 (15%) 10 (15%) 20 (30%)
Staphylococcus aureus 5 (7%) 4 (6%) 9 (13%)
MRSA 3 (4%) 2 (3%) 5 (7%)MSSA 0 1 (1%) 1 (1%)Unknown 2 (3%) 1 (1%) 3 (4%)
Streptococcus pneumoniae 3 (4%) 0 3 (4%)
Group B Streptococcus 2 (3%) 4 (6%) 6 (9%)
Pseudomonas aeruginosa 1 (1%) 1 (1%) 2 (3%)Bacterial Other** 2 (3%) 7 (10%) 9 (13%)
*Non-sterile sites include sputum, endotracheal aspirate, lung tissue, and stool **Stenotrophomonas maltophilia, Enterobacter cloacae, Staphylococcus saprophyticus, Staphylococcus coagulase negative, Enterococcal sepsis, Moraxella catarrhalis, Group A Streptococcus, Escherichia coli, VRE
![Page 37: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/37.jpg)
Summary of Deaths Related to Influenza A, Minnesota, April 2009 –
April 2010
In Spring wave• 4 deaths (all PCR-confirmed 2009 H1N1) • 2 in children; 1 in an adult age 65 or older • 1 with no underlying conditions• 100% 7-county MSP area
In Fall wave• 63 deaths (59 2009 H1N1, 4 Influenza A-type
unspecified)• 6 in children; 12 >
65 y• 7 no underlying conditions• 41% (26/63) 7-county MSP area
![Page 38: Novel A H1N1 Influenza in Minnesota › diseases › flu › stats › 2009h1n1.pdf · Flu A+ 2007-2008 % + 2008-2009 % + 2009-2010 % + Circulating Respiratory Viruses, Laboratory](https://reader033.vdocument.in/reader033/viewer/2022060501/5f1b9584c88f793f7a3ec2ef/html5/thumbnails/38.jpg)
For More Information Please Contact:
Minnesota Department of Health Acute Disease Investigation and Control
651-201-54141-877-676-5414
www.health.state.mn.us