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Electroceuticals and Electrodiagnostics
Roger Whittaker (IoN)
Patrick Degenaar (EEE)
OptoNeuro
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• Increasing prevalence of chronic diseases
• Poor compliance with oral medications
• Side effects with polypharmacy
• Lack of efficacy of current drugs
• Correct treatment is predicated on correct diagnosis
The healthcare need
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Electroceuticals
(bioelectronic medicine)
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• Relatively cheap to develop
• Controllability
• Fewer side effects
• Guaranteed compliance
• Tuneable to an individual patient
• Animal models
• Surgical implantation
• Neural interface
• Decoding neural signals
• Power and data transfer
• Longevity of devices
• Safety aspects
Advantages and challenges
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Neuroprosthetics @ Newcastle
Stimulate
Process
Record
http://www.optoneuro.eu
Epilepsy brain prosthesis
Visual prosthesis
Spinal cord injury
Hand/Leg bionics
Multi-EMG recording
Electrodiagnostics
http://www.cando.ac.uk
Closed loop neural
interfaces!!
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Injectable electronic systems
11.5 mm
2.1 mm
2.1 mm
Surgical neuroprosthetics Injectable bioelectronics
CANDO & Visual prosthesis
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Bioelectronic control
1. Nat Rev Endocrinol. 2012 Dec; 8(12): 743–754.
2. J Intern Med. 2011 Jan; 269(1): 45–53.
3. Immunol Rev. 2012 Jul; 248(1): 188–204.
P 𝑓(𝑡) 𝑑𝑓(𝑡)
𝑑𝑡
Can we start thinking applying classical of
methods of control to the human body?
+
𝑓(𝑡)