![Page 1: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/1.jpg)
VI Meeks, DDS, U Md Dental School
ORAL LESIONS ASSOCIATED
WITH HIV DISEASE
DR. VALLI MEEKS
UNIVERSITY OF MARYLAND
BALTIMORE COLLEGE OF
DENTAL SURGERY
![Page 2: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/2.jpg)
Oral Candidiasis (Thrush)
• pseudomembranous -
white or yellow plaques on
mucosa; leaves raw,
bleeding surface upon
wiping plaque away.
ORAL LESIONS ASSOCIATED WITH HIV DISEASE
VI Meeks, DDS, U Md Dental School
![Page 3: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/3.jpg)
Oral Candidiasis (Thrush)
• erythematous - mucosal
erythema (red macules or
patches); cytology smear or
culture is + for Candida/yeast.
VI Meeks, DDS, U Md Dental School
![Page 4: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/4.jpg)
Oral Candidiasis (Thrush)
• hyperplastic - white plaques
which cannot be wiped away.
VI Meeks, DDS, U Md Dental School
![Page 5: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/5.jpg)
Oral Candidiasis (Thrush)
• angular cheilitis - erythema,
fissures at labial commissures.
VI Meeks, DDS, U Md Dental School
![Page 6: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/6.jpg)
Periodontal Disease
• linear gingival erythema -
fiery, red band along free
gingival margin; also
punctate areas of erythema;
spontaneous bleeding may be
present.
VI Meeks, DDS, U Md Dental School
![Page 7: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/7.jpg)
Periodontal Disease
• necrotizing ulcerative
gingivitis (including ANUG) -
psuedomembrane of
interdental papillae (necrosis);
ulceration; fetor oris; pain.
VI Meeks, DDS, U Md Dental School
![Page 8: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/8.jpg)
Periodontal Disease
• necrotizing ulcerative gingivitis
- after 7 days of antibiotics.
VI Meeks, DDS, U Md Dental School
![Page 9: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/9.jpg)
Periodontal Disease
• necrotizing ulcerative
periodontitis - extremely rapid
and progressive destruction of
periodontal attachment and
bone; fetor oris; pain.
VI Meeks, DDS, U Md Dental School
![Page 10: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/10.jpg)
Periodontal Disease
• necrotizing ulcerative
periodontitis
VI Meeks, DDS, U Md Dental School
![Page 11: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/11.jpg)
CASE PRESENTATION:
Acute Necrotizing
Ulcerative
Periodontitis -
psuedomembrane of
interdental papillae
(necrosis); ulceration;
fetor oris; pain.
![Page 12: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/12.jpg)
![Page 13: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/13.jpg)
![Page 14: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/14.jpg)
![Page 15: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/15.jpg)
Healing after periodontal therapy
![Page 16: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/16.jpg)
Kaposi’s Sarcoma
• malignant neoplasm of blood
vessels; a reactive lesion.
VI Meeks, DDS, U Md Dental School
![Page 17: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/17.jpg)
Kaposi’s Sarcoma
VI Meeks, DDS, U Md Dental School
![Page 18: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/18.jpg)
Non-Hodgkin’s Lymphoma
• B-cell lymphoma; can appear
as necrotic, ulcerated mass or
nonulcerated, normal color or
erythematous mucosa; diagnosis
by biopsy.
VI Meeks, DDS, U Md Dental School
![Page 19: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/19.jpg)
Melanotic Pigmentation
• hyperpigmented, macular
lesions; asymptomatic; clinically
can be mistaken for Kaposi’s
Sarcoma.
VI Meeks, DDS, U Md Dental School
![Page 20: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/20.jpg)
Mycobacterium Tuberculosis
• usually pulmonary infection;
extrapulmonary lesions appear as
painful, indurated, nonhealing
ulcerated lesions.
VI Meeks, DDS, U Md Dental School
![Page 21: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/21.jpg)
Necrotizing Stomatitis
• extensive soft tissue necrosis
exposing underlying bone; often
no etiologic agent found.
VI Meeks, DDS, U Md Dental School
![Page 22: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/22.jpg)
Necrotizing Stomatitis
• 10 days after treatment
VI Meeks, DDS, U Md Dental School
![Page 23: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/23.jpg)
Ulceration Not Otherwise
Specified
• ulceration with a predilection for
the pharynx; characteristics of
ulceration is not recognized as any
pattern similar to aphthous
ulceration; may be related to
specific medications like ddC.
VI Meeks, DDS, U Md Dental School
![Page 24: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/24.jpg)
Salivary Gland Enlargement
• unilateral or bilateral
enlargement of salivary (parotid)
gland.
VI Meeks, DDS, U Md Dental School
![Page 25: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/25.jpg)
Thrombocytopenia Purpura
• dramatic decrease in platelet
count
• hemorrhage/spontaneous
bleeding of gingiva; bruises on
extremities.
VI Meeks, DDS, U Md Dental School
![Page 26: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/26.jpg)
Herpes Simplex
• vesicular lesions which rupture
becoming painful, irregular
ulcerations; intraorally, usually
found on tissue bound to bone,
e.g. palate
• herpetic lesion lasting longer
than 30 days is an AIDS defining
lesion
VI Meeks, DDS, U Md Dental School
![Page 27: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/27.jpg)
Papilloma; Focal Epithelial
Hyperplasia (FEH)
•“wart”; clinical appearance may
be flat (FEH) or spiky, cauliflower-
like; human papilloma virus
VI Meeks, DDS, U Md Dental School
![Page 28: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/28.jpg)
Papilloma; Focal Epithelial
Hyperplasia (FEH)
VI Meeks, DDS, U Md Dental School
![Page 29: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/29.jpg)
Papilloma; Focal Epithelial Hyperplasia (FEH)
VI Meeks, DDS, U Md Dental School
![Page 30: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/30.jpg)
Herpes Zoster (Shingles)
• activation of Varicella zoster
virus which has been dormant in
sensory nerve; unilateral, often
vesicular lesions.
VI Meeks, DDS, U Md Dental School
![Page 31: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/31.jpg)
Bacterial Infections
• A. israelii; E. coli; K. pneumoniae etiological agents
cultured from oral ulcerative or granulomatous lesions;
possible cause of slow/poor wound healing.
VI Meeks, DDS, U Md Dental School
![Page 32: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/32.jpg)
Bacillary (epithelioid)
Angiomatosis
• bacterial infection; causative
agent: Bartonella henselae /
Rochalimaea henselae; clinical
appearance can be mistaken for
Kaposi’s sarcoma.
VI Meeks, DDS, U Md Dental School
![Page 33: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/33.jpg)
Erythema Multiforme
• hypersensitivity reaction; acute, self-limiting process affecting skin
(target lesion) or mucous membranes - orally seen as ulcerations or
vesicular/bullous lesions.
VI Meeks, DDS, U Md Dental School
![Page 34: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/34.jpg)
Lichen Planus
• cell mediated immune response;
white keratotic lines (striae);
atrophic or erosive lesion
(desquamative).
VI Meeks, DDS, U Md Dental School
![Page 35: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/35.jpg)
Recurrent Aphthous Stomatitis
• raised, red border with necrotic,
depressed center
• minor
VI Meeks, DDS, U Md Dental School
![Page 36: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/36.jpg)
Recurrent Aphthous Stomatitis
• major
VI Meeks, DDS, U Md Dental School
![Page 37: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/37.jpg)
Recurrent Aphthous Stomatitis
• major, healed with scarring
VI Meeks, DDS, U Md Dental School
![Page 38: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/38.jpg)
Recurrent Aphthous Stomatitis
• herpetiform
VI Meeks, DDS, U Md Dental School
![Page 39: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/39.jpg)
Molluscum Contagiosum
• viral wart; spread via direct
contact
VI Meeks, DDS, U Md Dental School
![Page 40: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/40.jpg)
Cytomegalovirus
• usually causes eye
complications (CMV retinitis);
also can have intraoral ulceration
associated with the
cytomegalovirus; spread via
direct contact
• CMV is found in virtually all
body fluids; crosses
transplacental barrier; caution -
pregnant dental providers.
VI Meeks, DDS, U Md Dental School
![Page 41: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/41.jpg)
Xerostomia (dry mouth)
VI Meeks, DDS, U Md Dental School
![Page 42: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/42.jpg)
Vitamin Deficiency &
Angular Chelitis
VI Meeks, DDS, U Md Dental School
![Page 43: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/43.jpg)
Oral hairy leukoplakia
(OHL) is a viral
infection caused by
Epstein-Barr virus
(EBV).
![Page 44: ORAL LESIONS ASSOCIATED WITH HIV DISEASE - WV …dhhr.wv.gov/oeps/Documents/2012 Symposium Slides... · VI Meeks, DDS, U Md Dental School ORAL LESIONS ASSOCIATED WITH HIV DISEASE](https://reader033.vdocument.in/reader033/viewer/2022042801/5ad30a1d7f8b9abd6c8d611b/html5/thumbnails/44.jpg)
Treat for cosmetic
reasons; otherwise no
treatment is warranted
Use of Acyclovir or
topical Podophyllum
resin has been
reported to provide
relief
Oral Viral LesionsEpstein-Barr Virus (EBV)