MCGILLUNIVERSITY&GENOMEQUEBECINNOVATIONCENTREINVITESYOUTOTHEGUESTSPEAKERSEMINAR

MATHIEULUPIEN,Ph.D.

SeniorScientist,ThePrincessMargaretCancerCentreInvestigator,OntarioInstituteforCancerResearch

AssociateProfessor,DepartmentofMedicalBiophysicsUniversityofToronto

WEDNESDAY,DECEMBER20TH,201711:00am–12:00pm

StrathconaAnatomy&DentistryBuilding,RoomM/48Coffeeandlittlepastrieswillbeserved

TITLE: Metabolomics and cell of origin underlie cancer epigenomes SUMMARY:Cancer development is commonly ascribed to the genetic alterations, whetherinherited or acquired. These commonly promote epigenetic reprogramming toinducetranscriptionalprogramsfavorabletodedifferentiationandlong-termself-renewal.However,cancercanalsoariseindependentlyofgeneticalterations.Forinstance,pediatricependymomasarefreeofrecurrentgeneticalterations.Yet,theyharborepigeneticalterationsthatdrivetumorgrowth.Inthispresentation,wewillexploretheintricaterelationshipbetweengenetics,epigeneticsandmetabolomicsincancer.