Download - Research design & conduct service
NIHR Primary Care Interven1ons call • Broad defini1on of Primary Care
– “health care interven1ons or services delivered in primary care se=ngs”.
• Pa1ent involvement is important • Par1cularly interested in applica1ons that address:
– the management of long‐term condi1ons, the management of mul1ple morbidity or
– interven1ons that prevent acute admission to hospital – the effec1veness of exis1ng or new interven1ons – the benefits of new approaches to the delivery of services – mul1ple health related behaviours
4 eligible funding streams
• Efficacy and Mechanism Evalua1on (EME) • Health Services and Delivery Research (HS&DR)
• Health Technology Assessment (HTA) • Public Health Research (PHR)
Efficacy and Mechanism Evalua1on (EME)
• must evaluate the efficacy of an interven1on and may also include the evalua1on of mechanisms.
• The main clinical study must account for the majority of the costs
• may also include – ini1al stages – development of an interven1on – pilot/feasibility studies
Health Services and Delivery Research (HS&DR)
• research on different models of service delivery and pa1ent experience – new staff roles – compara1ve models of care – pa1ent‐centred care – changes in health systems – organisa1onal studies
Health Technology Assessment (HTA)
• evalua1ons of the clinical and cost effec1veness of interven1ons for the – diagnosis – management – monitoring – treatment or rehabilita1on of pa1ents
Public Health Research (PHR)
• non‐NHS public health interven1ons intended to improve the health of the public and reduce inequali1es in health.
• Seeking applica1ons looking at the role of primary care prac11oners in health promo1on or health protec1on work outside health service se=ngs.
Funding stream EME HS&DR HTA PHR Pre‐clinical No No No No Feasibility Yes Yes Yes Yes Pilot Yes Yes Yes Yes Phase I No Maybe No No Phase II Yes Maybe No No Phase III Yes Maybe Yes Yes Phase IV No Maybe Yes Yes Scoping Yes Yes Yes Yes Diagnos1c Yes Maybe Yes No
Systema1c review No Yes Yes Yes
Timings
• Call opening Thursday last week • Ends 22nd March • Funding decisions March 2014 • h^p://www.nihr.ac.uk/
Sta1s1cally significant?
Sta1s1cally significant
Sta1s1cally discernible
• more accurate • s1ll understandable • avoids confusion between clinical importance
Research Design & Conduct Service (RDCS)
Dr Mark Kelly
RDCS
Funded by NISCHR to formalise exis1ng research rela1onships with healthcare professionals
Covering HBs in SE Wales Consultancy to healthcare professionals for funding applica1ons
RDCS advises on ...
• focusing ideas and refining the research ques1on(s)
• building an appropriate research team • involving pa1ents and carers • choice and applica1on of research methodologies for both qualita1ve and quan1ta1ve approaches
• iden1fying the resources required for a successful project including iden1fying suitable funding opportuni1es
The service aims to provide users with:
• advice and support on all aspects of funding applica1ons
• links to experienced researchers for partner organisa1ons
• Successful funding bids!
RDCS team Mirella Longo Health Economist Dr Claire O’ Neill Qualitative research Vicky Roberts Research administrator
Dr Kirsten McEwan Psychology/Statistics Dr Mark Kelly Statistics
How the service operates
NHS worker thinks of a research idea
They email their R&D office
They email [email protected]
Logged in system ‐ request for support
form returned Request passed onto
RDCS consultant Consultant contacts NHS researcher and provides
support
Funding applica1on submi^ed (RDCS role
ends) Researcher provides feedback on outcome
How the service operates
• help desks
• presenta1ons and a^end conferences
• hos1ng events specifically linked to funding calls
• newsle^er/website
Progress
• To date we have advised on 105 projects • We have supported 15 Research for Public and Pa1ent Benefit funding bids
• All supported studies got through the first stage of RfPPB
• PATCH Art Therapy & Post‐natal Depression
• Topical vs oral gabapen1n for peripheral diabe1c neuropathy
• PLEAD • Phase 2 detox interven1on in prisoners on
remand for alcohol abuse • EDDY ‐ Early Detec1on of type 1 Diabetes
in Youth • RCT crossover trial of prostaglandin
F2alpha in thyroid eye disease • OPTIC: Op1mising Consent Processes in
Trials in Cri1cal Care • Rehabilita1on programme to support ill
military veterans achieve op1mal health and well‐being ‐ Phase 2 randomised controlled trial
• Final development and field tes1ng of scripted consulta1ons for human papillomavirus (HPV) tested women
• A feasibility study of an interven1on to improve the care of pa1ents with tuberous sclerosis in Wales
• Point‐of‐care tests to assist an1bio1c prescribing decisions for diabe1c foot ulcer infec1ons (INDUCE pilot study)
• A feasibility study to inform design of a defini1ve pragma1c randomised controlled trial to evaluate effec1veness and cost‐effec1veness of different methods of providing BRCA1/2 predic1ve test results.
• PROMiSE NHS: Pa1ent Reported Outcome Measures in Service Evalua1on: A pilot study for radical change management in the NHS
• Func1onal Assessments for People with Hun1ngton’s Disease
• Uptake Promo1on for Long Ac1ng Reversible Contracep1on: research to evaluate a simple interven1on in primary care.