SANGUI MEDINAL
MEDICALCOSMETIC
S
CHITOSKIN HEMO-SPRAY
Main OfficeAmman – JordanAbdullah Bin Rawaha St. Building No. 16 ArabiahTel: 55000000 Fax: 55000001www.abu-jabir.com
Jeddah – Saudi Arabia KingdomAl-Hammra – Tel: Fax:
Cairo – EgyptWill start on October 2008
BRANCHES
SANGUI
MEDICAL
CHITOSKIN®
A new universal and bio-active generation of wound-dressing based on Chitosan
Manufacture
By:
Distributed
By:
FUTURE HEALTHPharmacy, Medical Equipments, Dental
Instruments
& Cosmetics
What is chitosan and which are the sources?
Comment:
chitosan is poly-glucosamine
with few acetyl-groups
It is occurring in animals (connective tissue and cartilage) and in mushrooms.
Chitin
(poly-N-acetylglucosamine)
chitosan
de-acetylation
scrab shell
Product Description :
The patented wound dressing CHITOSKIN® consists of chitoskin and gelatin. It is a haemostyptic, very absorbent, absorbable and flexible gel that provides a moist healing environment at the surface of chronic and acute wounds. Tissue-like substances turn CHITOSKIN® into a biocompatible and painlessly removable wound dressing
Requirements for a wound dressing of high efficiencydrainage of exsudate
gas and water exchange
covering protection
template for cell growth
stimulation of cell activity
depot for special drugs
antimicrobic effects
detoxication:adsorption of endotoxin andinflammation mediators
A chronic wound needs many requirements for dressing and healing.
A chronic wound needs many requirements for dressing and healing.
Products Characteristics:
CHITOSKIN®
Absorbs bacteria and their toxins (endotoxin); antibacterial effect.
Forms a natural cell-milie absorbing excess wound fluid
Has a high exudate uptake capacity
Can be tailored in any way and is deformable
As tampon also suitable for deep wounds (i.e. decubital ulcers)
Not adherent to the wound bed.
Porous structure of CHITOSKIN®
CHITOSKIN® delivers a template for 3-dimensional tissue growth.
CHITOSKIN® delivers a template for 3-dimensional tissue growth.
100 µm
100 µm
INDICATIONS :
CHITOSKIN® - wound dressing is highly suitable for medical care of all the following wounds:
Acute wounds (i.e. burns, accidents, bullet wounds, donor sites and graft sites,..)
Chronic wounds (i.e. ulcer cruris (arterial/venous), decubitus ulcer, diabetic wounds, …)
Heavily exuding wounds
Secondary healing wounds
Infected wounds* ( In this case CHITOSKIN® can be applied, potentially additional treatment may be necessary.)
As tampon for deep wounds (decubitus ulcer, diabetic gangrene)
CONTRAINDICATIONS:
Contraindications are not yet known.
CHITOSKIN® was not tested with pregnant and nursing woman.
Influence of CHITOSKIN® on wound healing
The phases of wound healing
and the bio-active effects of CHITOSKIN®
phase I:hemostasisphase I:hemostasis
phase II:inflammationphase II:inflammation
phase III:proliferationphase III:proliferation
phase IV:differentiationphase IV:differentiation
1. anti-inflammatoryeffect
2. macrophage-activation
3. antibacterial effect
1. anti-inflammatoryeffect
2. macrophage-activation
3. antibacterial effect
1. increase ofproliferation
2. regulation by cytokines and growth factors
3. monomers as source for biosynthesis of glycosaminoglucanes
4. antibacterial effect
1. increase ofproliferation
2. regulation by cytokines and growth factors
3. monomers as source for biosynthesis of glycosaminoglucanes
4. antibacterial effect
1. regular deposition ofcollagen
2. stimulation and increase of epithelialisation
1. regular deposition ofcollagen
2. stimulation and increase of epithelialisation
1. hemostatic effect
2. antibacterial effect
1. hemostatic effect
2. antibacterial effect
CHITOSKIN® takes part in all phases of wound healing in bio-active manner and is therefore a universal wound dressing.
CHITOSKIN® takes part in all phases of wound healing in bio-active manner and is therefore a universal wound dressing.
Instruction for use:
Prepare the wound site by cleansing it mechanically or any other suitable way (debridement) and rinse with
Ringer- or isotonic saline solution.
Select a dressing that will allow CHITOSKIN® to cover the wound , if necessary cut into shape of the wound.
In most cases, the application of a dry dressing is sufficient, moisten the dressing only in case of dry or nearly
dry wounds.
To maintain a moist wound milieu CHITOSKIN® should be covered with a foilor a polymer dressing.
CHITOSKIN® needs to be secured with a non adhesive bandage.
This treatment should be continued up to epitheliation.
Tip: Due to potential pain and sensitivity of the skin avoid sticking anything on the wound edges and surroundings. Apply cotton or very soft fleece widely spread over the CHITOSKIN® covered wound area and fix with a gauze bandage. If necessary apply a compress bandage.
67 year old female, diabetic, chronic venous insufficiency, post-thrombotic syndrome
Before
After
Frequency of Change :
During the inflammation phase the dressing should be changed daily. When the wound is free of necroses and infections, CHITOSKIN® can be left in place for several days. As a general rule, the dressing should be replaced after 3 – 4 days.
Remaining wound dressing particles can easily be removed by rinsing with sterile Ringer-solution. Now, a new dressing can be applied as described above.
Single use Products:
CHITOSKIN® is a single use product. In case of damaged sterile package do not use!
Storage :
Keep dry and within the room temperature.
Product is sterilized using Gamma irradiation.
Content sterile unless peel package damged.
Packaging Content:
CHITOSKIN® - wound dressing
REF SIZE
4745 6 x 7,5 cm
10 x 10 cm
© 2005 SanguiBioTech GmbH, Witten, Germany11
Pharmacy, Medical Equipments
Dental Instruments
& Cosmetics
FUTURE HEALTH
Main Office
Jordan - Amman –
Abdullah Bin Rowaha St. Building no. 16
Tel: 00962 – 6 – 5527935 Fax: 00962 – 6 - 5527936
www. Abu-jabir.com
•Kingdom of Saudi Arabia•3220 Hussain Basalamah St. – Al Hamra’a – Unit No. 1
•Jeddah : 23212 – 7486 (Wasel) •Tel: 0092 6692023 – Fax: 0092 2843522
•Email: [email protected]
SanguiBio Tech GmbH Alfred-Herrhausen-Strasse 44
D – 58455 Witten GERMANY
www.sangui.de
•CAIRO – EGYPT
•Start on October 2008
•More about chitskin
© 2005 SanguiBioTech GmbH, Witten, Germany12
Curso de Tecnología Alemana en Pie Diabético y Heridas
Monterrey, N.L. - 23 y 24 de Febrero 2007
Topical Treatment of Chronic Skin
Ulcers with Haemoglobin:
Clinical Cases
W. K. R. Barnikol, H. Poetzschke
Bereich Klinische Physiologie, Universität Witten/Herdecke
58455 Witten (Ruhr), Germany
© 2005 SanguiBioTech GmbH, Witten, Germany13
83 years old female, diabetic, hypertension, pronounced
thrombosis syndrome, tcPO2 = 27 mmHg
Case 1
© 2005 SanguiBioTech GmbH, Witten, Germany14
© 2005 SanguiBioTech GmbH, Witten, Germany15
© 2005 SanguiBioTech GmbH, Witten, Germany16
Apr. 21
71 year old male, superficial non-healing ulcus,
Diagn.: Lymphedema, papillomatosis cutis lymphostatica,
congestion eczema
Case 2
© 2005 SanguiBioTech GmbH, Witten, Germany17
© 2005 SanguiBioTech GmbH, Witten, Germany18
© 2005 SanguiBioTech GmbH, Witten, Germany19
© 2005 SanguiBioTech GmbH, Witten, Germany20
Case 3:
54 year old female, severe chronic venous insufficiency
© 2005 SanguiBioTech GmbH, Witten, Germany21
© 2005 SanguiBioTech GmbH, Witten, Germany22
© 2005 SanguiBioTech GmbH, Witten, Germany23
© 2005 SanguiBioTech GmbH, Witten, Germany24
Case 4
40 year old male,
peripheral arterial
occlusive disease,
state after amputation
of the forefoot
© 2005 SanguiBioTech GmbH, Witten, Germany25
© 2005 SanguiBioTech GmbH, Witten, Germany26
May 24
Case 5
78 year old male, diabetic, arterial occlusive disease Fontaine IV
© 2005 SanguiBioTech GmbH, Witten, Germany27
© 2005 SanguiBioTech GmbH, Witten, Germany28
July 20
© 2005 SanguiBioTech GmbH, Witten, Germany29
Sept. 23
© 2005 SanguiBioTech GmbH, Witten, Germany30
Oct. 20
© 2005 SanguiBioTech GmbH, Witten, Germany31
Case 6
67 year old female, diabetic, chronic venous insufficiency, post-thrombotic syndrome
© 2005 SanguiBioTech GmbH, Witten, Germany32
© 2005 SanguiBioTech GmbH, Witten, Germany33
© 2005 SanguiBioTech GmbH, Witten, Germany34
© 2005 SanguiBioTech GmbH, Witten, Germany35
June 28
Case 7
68 year old female, post thrombotic syndrome, open leg since 4 years
© 2005 SanguiBioTech GmbH, Witten, Germany36
July 30
HemO2spray therapy starting on July 20
© 2005 SanguiBioTech GmbH, Witten, Germany37
Aug. 12
© 2005 SanguiBioTech GmbH, Witten, Germany38
NANO TECHNOLOGY COSMETICS
Very small.Very efficient.Pure MoistureNano TechnologyCosmetics.
© 2005 SanguiBioTech GmbH, Witten, Germany40
THE REVOLUTION IN SKIN CARE
Outstanding improvement of skin elasticity of more than 60%,
less wrinkles and lines,
overall tighter and healthier skin (cellulitis)
suitable for all skin types
© 2005 SanguiBioTech GmbH, Witten, Germany41
COMMITMENT
Sangui BioTech is totally commited to products that really help and
serve people. We believe in reality, not virtuality. Our products must
all stand this test: Do our patients and customers get a real benefit?
Do our products really offer new aspects and alternatives? If the
answer is yes, we proceed. This is true with our wound care medical
products, that have opened new horizons in the treatment of
chronic wounds, this is true with our revolutionary blood additive
project, and this is also true with our cosmetic products. We offer
women all over the world a new and proven concept to thoroughly
regenerate their skin.
We don‘t engage in look-alikes. We engage in innovations.
© 2005 SanguiBioTech GmbH, Witten, Germany42
COMPETENCE
Sangui BioTech is researching and developing in the pharmaceutical, medical and cosmetic fields. Our portfolio comprises of haemoglobin based products, innovative wound pads, and this series of cosmetic products which are radically new and exclusive. Like anything else we do. The underlying technology is patented. It is the result of deep research by scientific experts who combine their expertise to find solutions of both the dermatological and the physical issues involved. We did not copy any existing concepts, but rather chose to start from scratch with just an open mind. That is why it is so radically different, and that is why it works. And we prove: Whilst a boost of skin elasticity of 20% is considered a huge effort, and 25% may well be the pinnacle so far, we achieved an improvement of more than 60%. After all, this is what really counts.
© 2005 SanguiBioTech GmbH, Witten, Germany43
NANO BEAUTY + HYALURON
Intense skin repair with Hyaluronic Acid
Immediate and lasting effect
Boost for radiant skin
© 2005 SanguiBioTech GmbH, Witten, Germany44
NANO BEAUTY + HYALURON
Hyaluronic Acid has become one of the most sought after agents for moisturizing and unwrinkling of the older skin. As the body ages, its own production of hyaluronic Acid fades, and so does the natural elasticity of the skin. It ages.
Hyaluronic acid applied by Sanguis Nano Beauty plus Hyaluron adds to the skin what is missing, without the need of needles and injections or other harmful ways to penetrate the skin. It just finds its natural way where it is needed. This is the way it should be.
© 2005 SanguiBioTech GmbH, Witten, Germany45
NANO BODY CARE
Nano Technology to boost firmness of skin
Anti-cellulite care with proven results of more than 60% improved skin elasticity (Dermatest, Muenster/Germany)
© 2005 SanguiBioTech GmbH, Witten, Germany46
NANO FACE CARE
An oxygen boost to face, neck and décolleté
Revolutionary anti-aging care
Suitable for delicate skin types
See & feel the difference
© 2005 SanguiBioTech GmbH, Witten, Germany47
NANO FACE PURIFIER
Nano Purifier to thoroughly clean delicate skin of face, neck and décolleté, leaving it soft and moisturized at the same time
Ideal preparation for further treatment
© 2005 SanguiBioTech GmbH, Witten, Germany48
FACE CARE DAY CREAM
• Luxury special day care cream to complete the Nano Face Treatment
• High quality nutrition for complete regeneration
© 2005 SanguiBioTech GmbH, Witten, Germany49
YOUNG AND OLDER SKIN Microscopic view through the skin of a 21-and a 66-year old
Change of the structural and bio-chemistry parameter:
• Degeneration of collagen- und elastine fibres, glycoproteins
• Degeneration of the microvascular systems
• Reduction of density of the capillary density
• Reduced capacity of metabolism
• Increase of dryness, caused by degradation of glucosaminoglucans
© 2005 SanguiBioTech GmbH, Witten, Germany50
COLLAGEN SYNTHESIS IS DEPENDENT ON SUBSTRATES
The collagen synthesis is governed amongst others by:
• amino acids• oxygen• ascorbic acid• Fe 2+-Ions
© 2005 SanguiBioTech GmbH, Witten, Germany51
NO SCALPELS OR INJECTIONSREGENERATION INSTEAD
With Pure Moisture Nano cosmetics, we reach naturally were it really counts, at the collagen level. Therefore, no devices such as scapels or hypodermic needles or injections are needed. The skin stays intact, as it should be.
© 2005 SanguiBioTech GmbH, Witten, Germany52
VISIBLE RESULTS
results after 1 week
results after 3 weeks
© 2005 SanguiBioTech GmbH, Witten, Germany53
By RENATE PENTZIEN
Renate Pentzien is the driving force behind developing the Pure Moisture brand.She caught on early onto the benefits to her skin by using Pure Moisture products and has been the ambassador for the Pure Moisture brand ever since. She is constantly looking for improvement of our cosmetic series, and so are we.
© 2005 SanguiBioTech GmbH, Witten, Germany54
WATER AND OXYGEN ARE EXISTENTIAL EVERYWHERE... ON PLANET MARS OR WITHIN THE SKIN
Water
The human body consists of approx. 80% water. Likewise a live cell consists of 90% water.
Oxygen
Without oxygen cells can‘t generate energy
boosts regeneration (collagen- and GAG-synthesis)
activates micro circulation
boosts Angiogenesis
is absorbed by the skin
boosts cell division
© 2005 SanguiBioTech GmbH, Witten, Germany55
PATENTED OXYGEN SUPPLY IN PURE MOISTURE PRODUCTS
US Patent pending
EU granted
© 2005 SanguiBioTech GmbH, Witten, Germany56
CERTIFIED NANO TECHNOLOGY
CAN Nanotechnology Centre, Hamburg/Germany, certifies Pure Moistures liquid nano structures
© 2005 SanguiBioTech GmbH, Witten, Germany57
CAN (CENTRE FOR NANOTECHNOLOGY)
Evaluation and measurement of liquid nano structures in Pure Moisture products
© 2005 SanguiBioTech GmbH, Witten, Germany58
TESTING THE ELASTICITY OF THE SKIN
The 61,66 %
Improvement
Certificate
© 2005 SanguiBioTech GmbH, Witten, Germany59
DIN EN ISO 9001:2000
SanguiBioTech is ISO certified
© 2005 SanguiBioTech GmbH, Witten, Germany60
SanguiBioTech is totally dedicated to product safety. As a certified manufacturer of cosmetic and medical products, we know that product safety is paramount to everything we do. Therefore, all products are thoroughly tested and checked before released into the market. All ingredients come with data sheets and safety analyses , and only material of the highest standards are used in our products. Sangui BioTech also believes in restriction. Therefore, only what is absolutely necessary will find its way into our products. Less is more. Where possible, preservatives are excluded or used at minimum levels. No animals are tested.
SAFETY FIRST
© 2005 SanguiBioTech GmbH, Witten, Germany61
DERMATEST CERTIFIES VERY GOOD QUALITY
Dermatest GmbH Muenster/Germany, certifies Pure Moisture as dermatologically tested – with very good acceptance
no allergic reactions
© 2005 SanguiBioTech GmbH, Witten, Germany62
By RENATE PENTZIEN
A revolutionary cosmetic series developed by
SanguiBioTech GmbH, Germany
© 2005 SanguiBioTech GmbH, Witten, Germany63
Contact
SanguiBioTech GmbH
Alfred-Herrhausen Strasse 44
D-58455 Witten/Herdecke
Tel. 0049 2302 915 200
Fax: 0049 2302 915 191
www.sangui.de
www.puremoisture.de
© 2005 SanguiBioTech GmbH, Witten, Germany64
NANO TECHNOLOGY COSMETICS